王韫芳｜清华大学｜学者主页

2026

类器官生物学 = Organoid biology

王韫芳

《科学出版社》

2026

库普弗细胞在对乙酰氨基酚诱导的急性肝损伤中的变化及功能研究

张祥颂，王璇，曹延楠，王韫芳，闫军

《军事医学》

2026

Modern xenotransplantation: rewiring glycan-mediated immunogenicity via genome-glycome convergence

Mingshuo Wang, Qing Wang, Yakun Liu, Jiatong Xu, Yu-Xin Su, Hui Bai, Yunfang Wang, Jiahong Dong

EBioMedicine

DOI

2026

Decoding the pre-malignant niche in cholangiocarcinoma: A single-cell multi-omic atlas from inflammation to invasion.

Siming Kong, Rongyan Yao, Hui Bai, Canhong Xiang, Yunfang Wang

Journal of Clinical Oncology

DOI

2026

THU-323 Integrated proteomic and glycoproteomic landscape of human and pig liver: a cross-species comparative analysis

Yakun Liu, Rongyan Yao, Siming Kong, Mingshuo Wang, Congwen Bian, Bin Wang, Tianzi Luo, Hui Bai, Yunfang Wang, Zhong Zeng, Jiahong Dong

Journal of Hepatology

DOI

2026

Comprehensive Transcriptomic and Proteomic Profiling of CILD40 with Novel Compound Heterozygous Mutations of DNAH9

Siming Kong, Mingshuo Wang, Xue-Dong Wang, Yakun Liu, Pengfei Wang, Wenyan Song, Ziye Chen, Yu-Xin Su, Canhong Xiang, Yunfang Wang, Hui Bai

Phenomics

DOI

2026

THU-077 Systematic drug screening in a patient-derived bile duct organoid biobank deciphers context-dependent bile duct injury mechanisms

Zi-Ye Chen, Tianzi Luo, Mingming Ren, Yadi Geng, Yakun Liu, Mei-Dai Liang, Zi-Xuan Wang, Hui Bai, Yunfang Wang

Journal of Hepatology

DOI

2026

TOP-328 Single-cell and spatial transcriptomic profiling of cross-species livers: evaluating genetically engineered pig livers for clinical xenotransplantation

Siming Kong, Mingshuo Wang, Rongyan Yao, Yakun Liu, Congwen Bian, Bin Wang, Tianzi Luo, Hui Bai, Yunfang Wang, Zhong Zeng, Jiahong Dong

Journal of Hepatology

DOI

2025

分区特异性肝脏类器官的构建与层级功能性肝小叶的制备及其在肝脏疾病建模与药物评价中的应用（英文）

柳娟，王琪，陈虹宇，阴雯臻，刁金美，马文瑞，宿钰鑫，乐银鹏，金葆青，董家鸿，王韫芳

Science Bulletin

2025

类器官研究的创新突破与转化应用：技术、应用与政策的多维视角

白卉，陈子叶，王铭铄，罗天姿，王韫芳

《中国细胞生物学学报》

2025

ARID1A-Deficient and 11q13-Amplified Metastatic Pancreatic Cancer Initially Presenting as Retroperitoneal Fibrosis in a Patient with Familial CHEK2 Variant

Siming Kong, Tongxin Cao, Yakun Liu, Xue-Dong Wang, Mingshuo Wang, Tianzi Luo, Yunfang Wang, Pengfei Wang, Hui Bai

Diagnostics

DOI

2025

Primary Cilia: Hub of Cell Signal Transduction and Emerging Role in Digestive System Tumorigenesis

Wenyan Song, Mingshuo Wang, Siming Kong, Yakun Liu, Xin-Long Yan, Hui Bai, Yunfang Wang

Cell Biochemistry and Function

DOI

2025

Heterotaxy polysplenia syndrome with cholangiopancreatic cancer: a case report and literature review

Ziye Chen, Yu-An Chen, Xue-Dong Wang, Wenyan Song, Yadi Geng, Pengfei Wang, Siming Kong, Jiahong Dong, Hui Bai, Yunfang Wang

Frontiers in Medicine

DOI

2025

Innovative Construction and Application of Bile Duct Organoids: Unraveling the Complexity of Bile Duct Diseases and Potential Therapeutic Strategies.

Yadi Geng, Ziye Chen, Tianzi Luo, Yakun Liu, Siming Kong, Xin-Long Yan, Hui Bai, Yunfang Wang

Cancer Letters

DOI

2025

A Scalable Human Liver-on-a-Chip Platform for Predictive Safety Assessment.

Gauri Kulkarni, Lizao Chen, Jing Sang, Ji Hye Seo, R. Grall, Yunfang Wang, Paige Gilbride, Yu-Chieh Yuan, Matthew Albaum-Getzen, Jenna McCormack, Jingzhe Ma, Alyssa Fanelli, L. Meng, Bei-Bei Xu, Xuhai Huang, Thomas Marshall, Hardeep Singh, Xiaohua Qian, Zhiyong Xie, Hui Bai, Longlong Si, Chun-Mei Ding, G. Ouedraogo, R. Kuang, Xin Xie, H. Bai

Toxicology

DOI

2024

3D‐Bioprinting for Precision Microtissue Engineering: Advances, Applications, and Prospects

Jinrun Liu, Jinrun Liu, Qi Wang, Yinpeng Le, Min Hu, Li Chen, Ni An, Qingru Song, Wenzhen Yin, Wenrui Ma, Mingyue Pan, Yutian Feng, Yunfang Wang, Lu Han, Juan Liu, Juan Liu

Advanced Healthcare Materials

DOI

2024

Bioactive scaffolds for tissue engineering: A review of decellularized extracellular matrix applications and innovations

Juan Liu, Qingru Song, Wenzhen Yin, Chen Li, Ni An, Yinpeng Le, Qi Wang, Yutian Feng, Yuelei Hu, Yunfang Wang

Exploration

DOI

2024

Region-specific cellular and molecular basis of liver regeneration after acute pericentral injury

Shuyong Wang, Xuan Wang, Yiran Shan, Zuolong Tan, Yuxin Su, Yannan Cao, Shuang Wang, Jiahong Dong, Jin Gu, Yunfang Wang

Cell stem cell

DOI

2023

The role of altered lipid composition and distribution in liver fibrosis revealed by multimodal nonlinear optical microscopy

Hao Jia, Juan Liu, T. Fang, Zhen Zhou, Ruihong Li, Wenzhen Yin, Yao Qian, Qi Wang, Wan-Hui Zhou, Chang Liu, Ding-Cheng Sun, Xun Chen, Zheng Ouyang, Jia-Hong Dong, Yunfang Wang, Shuhua Yue

Science Advances

DOI

2023

Non-invasive preeclampsia prediction using plasma cell-free RNA signatures.

Si Zhou, Jie Li, Wenzhi Yang, Peng Xue, Yan-Ning Yin, Yunfang Wang, Peirun Tian, Huanhuan Peng, Huiyan Jiang, Wenqiu Xu, Shang Huang, Shu-ying Li, Rui Zhang, Feng-Xiang Wei, Haixi Sun, Jianguo Zhang, Li-Jian Zhao

American Journal of Obstetrics and Gynecology

DOI

2023

Hepatic mitochondrial NAD+ transporter SLC25A47 activates AMPKα mediating lipid metabolism and tumorigenesis

Lili Cheng, R. N. V. Krishna Deepak, Guoqiang Wang, Ziyi Meng, Lei Tao, Mengqing Xie, Wenna Chi, Yuming Zhang, Mingming Yang, Yilie Liao, Rui-Qun Chen, Yu Liang, Junyu Zhang, Yuedong Huang, Weihua Wang, Zhiying Guo, Yunfang Wang, Jian-Die D. Lin, Hao Fan, Li-Gong Chen

Hepatology

DOI

2023

Mobility-Modulated Sequential Dissociation Analysis Enables Structural Lipidomics in Mass Spectrometry Imaging.

Yao Qian, Xiangyu Guo, Yunfang Wang, Zheng Ouyang, Xiao-Xiao Ma

Angewandte Chemie

DOI

2022

基于类器官活库的肝胆精准诊疗新范式

王韫芳

《中国医学前沿杂志(电子版)》

2022

Hepatic Organoid-Based High-Content Imaging Boosts Evaluation of Stereoisomerism-Dependent Hepatotoxicity of Stilbenes in Herbal Medicines

Juan Liu, Tingting Li, Ruihong Li, Jie Wang, Pengyan Li, Ming Niu, Le Zhang, Chun-yu Li, Tao Wang, Xiaohe Xiao, Jia-Bo Wang, Yunfang Wang

Frontiers in Pharmacology

DOI

2022

Lapatinib Suppresses HER2-Overexpressed Cholangiocarcinoma and Overcomes ABCB1– Mediated Gemcitabine Chemoresistance

Zhiqing Bai, Zhi-Ying Guo, Jia-Xing Liu, Yu-An Chen, Q. Lu, Ping Zhang, Lili Hong, Yunfang Wang, Jia-Hong Dong

Frontiers in Oncology

DOI

2022

Tandem Mass Spectrometry Imaging Enables High Definition for Mapping Lipids in Tissues.

Xiang-Yu Guo, Wenbo Cao, Xiao-Min Fan, Zhiying Guo, Dong-Hui Zhang, H. Zhang, Xiaoxiao Ma, Jiahong Dong, Yunfang Wang, Wenpeng Zhang, Z. Ouyang

Angewandte Chemie

DOI

2022

Generation of multicellular tumor spheroids with micro-well array for anticancer drug combination screening based on a valuable biomarker of hepatocellular carcinoma

Qi Wang, Juan Liu, Wenzhen Yin, Dawei Sun, Zhongsong Man, Shan-Shan Jiang, Xiu-Fang Ran, Yuxin Su, Yunfang Wang, Jia-Hong Dong

Frontiers in Bioengineering and Biotechnology

DOI

2022

In-Vivo Monitoring of Liver Regeneration by Ultrasound Localization Microscopy: A Feasibility Study

Rui Wang, Yuelei Hu, Li-Jie Huang, Qiong He, Yunfang Wang, Lin Zhang, Jian-Wen Luo

IUS

DOI

2022

sn-1 Specificity of Lysophosphatidylcholine Acyltransferase-1 Revealed by a Mass Spectrometry-Based Assay.

Xue Zhao, Jiaqi Liang, Ziye Chen, Rui-Jun Jian, Yao Qian, Yunfang Wang, Zhiying Guo, Wenpeng Zhang, Y. Zhang, H. Yin, Yu Xia

Angewandte Chemie

DOI

2022

High-content imaging of human hepatic spheroids for researching the mechanism of duloxetine-induced hepatotoxicity

Juan Liu, Ruihong Li, Ting-Ting Zhang, Rui Xue, Ting-Ting Li, Zheng Li, Xiao-Mei Zhuang, Qi Wang, Yu Chen, Jia-Hong Dong, Youzhi Zhang, Yunfang Wang

Cell Death and Disease

DOI

2022

Co-administration of MDR1 and BCRP or EGFR/PI3K inhibitors overcomes lenvatinib resistance in hepatocellular carcinoma

Dawei Sun, Juan Liu, Yunfang Wang, Jia-Hong Dong

Frontiers in Oncology

DOI

2021

Human primary epidermal organoids enable modeling of dermatophyte infections

Xuan Wang, Shuyong Wang, Baolin Guo, Yuxin Su, Zuolong Tan, Ming-Yang Chang, Jin-Mei Diao, Yi Zhao, Yunfang Wang

Cell Death and Disease

DOI

2021

Fibrinogen improves liver function via promoting cell aggregation and fibronectin assembly in hepatic spheroids

Ruihong Li, Juan Liu, Jie Ma, Xuer Sun, Yi Wang, Yi Wang, Jiexin Yan, Qunfang Yu, Jinmei Diao, Chun Yang, Lola McAdams Reid, Yunfang Wang, Yunfang Wang

Biomaterials

DOI

2020

药物肝毒性评价体外细胞模型的相关研究进展

李瑞红，柳娟，孙旭尔，王韫芳

《生命科学仪器》

2020

三维HepaRG细胞模型的建立及对曲格列酮肝毒性评价

张弛，李凤祥，彭辉，王韫芳，赵君，郭家彬，彭双清

《毒理学杂志》

DOI

2020

Clinical characteristics of the recovered COVID-19 patients with re-detectable positive RNA test

Jiang-Hong An, Xue-Jiao Liao, Tong Xiao, Shen Qian, Jing Yuan, Haocheng Ye, Furong Qi, Chengguang Shen, Yang Liu, Lifei Wang, Xiao Cheng, Na Li, Qing-Xian Cai, Fang Wang, Jun Chen, Ying-Xia Liu, Yunfang Wang, Feng Zhang, Yang Fu, Xiao-Hua Tan, Lei Liu, Zheng Zhang

medRxiv

DOI

2020

The lncRNA XIST promotes proliferation, migration and invasion of gastric cancer cells by targeting miR-337.

Wen-Qi Zheng, Juan Li, Xue Zhou, L. Cui, Yunfang Wang

Arab Journal of Gastroenterology

DOI

2020

Auto Micro Atomization Delivery of Human Epidermal Organoids Improves Therapeutic Effects for Skin Wound Healing

Mingyang Chang, Juan Liu, Baolin Guo, Xin De Fang, Yi Wang, Yi Wang, Shuyong Wang, Xiaofang Liu, Lola McAdams Reid, Yunfang Wang, Yunfang Wang

Frontiers in Bioengineering and Biotechnology

DOI

2019

构建三阴性乳腺癌的三维体外培养模型用于抗肿瘤药物的活性评价

王杰，李婷婷，李瑞红，陈志强，周元园，王韫芳，柳娟，张宏艳

《安徽医科大学学报》

DOI

2019

肝细胞外基质促进人胚胎干细胞肝向诱导分化的实验研究

孙旭尔，颜洁心，余群芳，李瑞红，柳娟，王韫芳

《军事医学》

2018

小鼠胎肝细胞透明质酸3D培养体系的建立

颜洁心，王怡，王韫芳

《生物化学与生物物理进展》

2018

异种(猪)脱细胞真皮基质粉对表皮细胞和成纤维细胞的促进作用

常铭洋，陈志强，柳娟，闫舫，季守平，王韫芳

《中华损伤与修复杂志(电子版)》

2018

猪皮细胞外基质促进创伤小鼠再表皮化的实验研究

郭宝林，陈志强，王术勇，闫舫，王韫芳

《军事医学》

2017

基于类器官3D培养和高内涵成像的药物肝毒性评价模型研究

李朋彦，李春雨，陆小华，石伟，高源，崔鹤蓉，李婷婷，柏兆方，肖小河，王韫芳，王伽伯

《药学学报》

DOI

2017

基于类器官3D培养的何首乌易感物质肝毒性评价

李婷婷，李瑞红，刘振兴，张乐，王杰，常乐，陈志强，施艳霞，李朋彦，李春雨，刘建红，柏兆方，王伽伯，王韫芳，柳娟，肖小河

《药学学报》

2017

小分子化合物诱导人胃上皮细胞直接转化为内胚层多潜能祖细胞

王韫芳，Jinhua Qin，Shuyong Wang，Wencheng Zhang，Jialei Duan，Jing Zhang，Xin Wang，Fang Yan，Mingyang Chang，Xiaofang Liu，Bo Feng，Jiang Liu，裴雪涛

《科学新闻》

2014

间充质干细胞无异源/无血清培养基研发的现状和前景

张文成，常铭洋，王韫芳，裴雪涛

《中国医药生物技术》

2013

干细胞治疗糖尿病的研究现状及展望

刘晓芳，王韫芳，李亚里，裴雪涛

《中国科学:生命科学》

2013

Lgr5和CD44在肠息肉和结直肠癌中的表达及意义

柴宁莉，张文成，王艳敏，周昭涛，张艳娥，刘红艳，万军，覃金华，王术勇，王韫芳，裴雪涛，吴本俨，令狐恩强

《南方医科大学学报》

2012

无血清培养基SYL-SF对间充质干细胞的培养和扩增作用

张文成，王韫芳，常铭洋，池木根，孔维霞，裴雪涛，吴祖泽

《中国医药生物技术》

2012

临床研究用间充质干细胞的体外制备策略

张文成，王韫芳，常铭洋，池木根，王华，刘银霞，覃金华，闫舫，裴雪涛，吴祖泽

《中国医药生物技术》

2010

不同浓度葡萄糖对人血管内皮细胞的影响

李伟娟，刘秀玲，王韫芳，南雪，尚小明，刘阁玲

《山东医药》

2010

经体外预处理人胎儿骨髓间充质干细胞的潜在自身成瘤性

胡洁，杨丽娟，王韫芳，周慧敏，魏林，王润田，裴雪涛

《军事医学》

2009

单克隆来源的小鼠胎肝HPP-CFC肝上皮分化潜能的研究

周军年，王韫芳，要晖宇，贺文艳，陈海旭，李思霆，史岩，施双双，南雪，白慈贤，刘兵，岳文，毛宁，裴雪涛

《生物化学与生物物理进展》

2009

人羊水来源MSC的分离培养鉴定及其免疫抑制特性的初步研究

胡洁，杨丽娟，刘慧，王韫芳，岳文，魏林，王润田，裴雪涛

《军事医学》

2008

用慢病毒转染RNAi技术沉默胆固醇7α羟化酶的基因表达,降低肝细胞中胆汁酸的分泌

郑吉春，裴海云，杨印祥，姚海雷，罗海英，王婧，陈琳，南雪，白慈贤，王韫芳，岳文，裴雪涛

《生物物理学报》

2008

生物支架材料胶原膜交联前后的特性分析

陈琳，吕洋，管利东，王韫芳，何丽娟，李艳华，白慈贤，刘大庆，裴雪涛

《中国修复重建外科杂志》

2008

大鼠肝移植急性排斥反应模型的建立与评价

罗海英，翟树森，张玉君，白慈贤，尉承泽，孔维，王韫芳，裴雪涛

《生物技术通讯》

2008

腺病毒介导CTLA4Ig及CTLA4双基因在骨髓间充质干细胞中的表达

罗海英，王韫芳，南雪，白慈贤，施双双，尉承泽，孔维，裴雪涛

《解放军医学杂志》

2008

CTLA4基因修饰骨髓间充质干细胞向肝细胞诱导分化及其免疫抑制功能研究

罗海英，王韫芳，翟树森，张玉君，南雪，白慈贤，施双双，尉承泽，岳文，孔维，裴雪涛

《生物化学与生物物理进展》

2008

静态单轴拉伸应变刺激对细胞有丝分裂方向的影响

王婧，胡青华，米强，赵磊，周军年，秦立蓬，杨春，王韫芳，庄逢源

《生物化学与生物物理进展》

2008

siRNA沉默socs3对红系发育的影响

刘雨潇，吉蕾，袁红丰，陈琳，薛郡，管兆轩，南雪，白慈贤，王韫芳，岳文，裴雪涛

《生物化学与生物物理进展》

2007

自体骨髓间充质干细胞为种子细胞构建组织工程化全层皮肤

何丽娟，南雪，王韫芳，管利东，白慈贤，施双双，袁红丰，陈琳，刘大庆，裴雪涛

《中国科学:生命科学》

2007

慢病毒介导的稳定表达bFGF的胎儿肝脏基质细胞株的建立

习佳飞，王韫芳，张鹏，袁红丰，施双双，闫舫，陈琳，白慈贤，南雪，裴雪涛

《生物化学与生物物理进展》

2007

胚胎干细胞：从基础到临床有多远

裴海云，王韫芳，裴雪涛

《中华实验外科杂志》

2007

胆汁酸代谢对肝细胞功能的影响

郑吉春，王韫芳，裴雪涛

《肝脏》

2007

胚胎干细胞自我复制及亚全能分化特性维持的分子机制

刘雨潇，吉蕾，王韫芳，裴雪涛

《中国科学:生命科学》

2007

同种异体骨髓间充质干细胞心内膜移植治疗小型猪急性心肌梗死

程芮，王士雯，张友荣，徐勇，孟玲，王韫芳，李艳华，裴雪涛

《临床心血管病杂志》

2007

肝细胞微囊化移植——肝病细胞治疗的新希望

滕越，王韫芳，裴雪涛

《自然科学进展》

2007

人脂肪来源干细胞在模拟微重力环境中的生长特性

管利东，王韫芳，刘大庆，岳慧敏，张鹏，白慈贤，闫舫，南雪，施双双，裴雪涛

《自然科学进展》

2007

siRNA沉默HIF-1α对胎肝基质细胞SDF-1α表达的影响

吉蕾，习佳飞，袁红丰，张鹏，刘雨潇，王韫芳，施双双，陈琳，南雪，白慈贤，裴雪涛

《生物化学与生物物理进展》

2007

神经元限制性沉默因子对人胰岛素基因转录调控作用的研究

刘庆斌，李艳华，杨印祥，袁红丰，张锐，秦立蓬，吕洋，张赛男，孙迪金，陈琳，白慈贤，南雪，王韫芳，裴雪涛

《生物化学与生物物理进展》

2007

表皮形态发生素(Epimorphin)与表皮形态发生

周军年，王韫芳，裴雪涛

《中国生物化学与分子生物学报》

2006

成体干细胞及其在再生医学中的应用

习佳飞，王韫芳，裴雪涛

《生命科学》

2006

Wnt 3a在神经干细胞向多巴胺能神经元分化过程中作用的研究

韩姝，师伟，李艳华，姚海雷，谢小燕，陈琳，施双双，白慈贤，南雪，闫舫，王韫芳，裴雪涛

《生物化学与生物物理进展》

2006

一种改良帕金森大鼠模型的制作

苏平，李艳华，郑敏，管利东，王韫芳，陆兵勋，裴雪涛

《广东医学》

2005

组织工程血管研究现状

岳慧敏，梁峰，王韫芳，裴雪涛

《自然科学进展》

2005

混合细胞共微囊化对肝细胞功能的支持作用

王韫芳，薛毅珑，南雪，梁峰，罗芸，李雁凌，高宇红，岳文，裴雪涛

《中华医学杂志》

2005

治疗性克隆与造血干细胞移植

裴雪涛，习佳飞，王韫芳

《中华医学杂志》

2005

3种不同途径移植自体骨髓间充质干细胞治疗急性心肌梗死效果比较

程芮，王士雯，张友荣，孟玲，曹丰，徐勇，王韫芳，裴雪涛

《中华实验外科杂志》

2005

应用自制心内膜注射导管移植自体骨髓间充质干细胞治疗急性心肌梗死

程芮，王士雯，曹丰，张友荣，徐勇，孟玲，王韫芳，李艳华，卢才义，裴雪涛

《中华老年心脑血管病杂志》

2005

肝干细胞及其在肝再生医学中的应用

南雪，王韫芳，裴雪涛

《自然科学进展》

2004

干细胞治疗及其临床应用:科学性、有效性、安全性、可控性

裴雪涛，王韫芳

《中华老年多器官疾病杂志》

2004

成体干细胞:从基础到临床

王韫芳，裴雪涛

《中华医学杂志》

2004

脑源性神经营养因子基因转导对骨髓间充质干细胞向神经细胞分化的影响

赵连旭，张杰，孟玲，曹丰，王冬梅，南雪，李艳华，王韫芳，徐小虎，裴雪涛

《中华医学杂志》

精选作品

期刊论文

类器官生物学 = Organoid biology

库普弗细胞在对乙酰氨基酚诱导的急性肝损伤中的变化及功能研究

Modern xenotransplantation: rewiring glycan-mediated immunogenicity via genome-glycome convergence

Decoding the pre-malignant niche in cholangiocarcinoma: A single-cell multi-omic atlas from inflammation to invasion.

THU-323 Integrated proteomic and glycoproteomic landscape of human and pig liver: a cross-species comparative analysis

Comprehensive Transcriptomic and Proteomic Profiling of CILD40 with Novel Compound Heterozygous Mutations of DNAH9

THU-077 Systematic drug screening in a patient-derived bile duct organoid biobank deciphers context-dependent bile duct injury mechanisms

TOP-328 Single-cell and spatial transcriptomic profiling of cross-species livers: evaluating genetically engineered pig livers for clinical xenotransplantation

分区特异性肝脏类器官的构建与层级功能性肝小叶的制备及其在肝脏疾病建模与药物评价中的应用（英文）

类器官研究的创新突破与转化应用：技术、应用与政策的多维视角

ARID1A-Deficient and 11q13-Amplified Metastatic Pancreatic Cancer Initially Presenting as Retroperitoneal Fibrosis in a Patient with Familial CHEK2 Variant

Primary Cilia: Hub of Cell Signal Transduction and Emerging Role in Digestive System Tumorigenesis

Heterotaxy polysplenia syndrome with cholangiopancreatic cancer: a case report and literature review

Innovative Construction and Application of Bile Duct Organoids: Unraveling the Complexity of Bile Duct Diseases and Potential Therapeutic Strategies.

A Scalable Human Liver-on-a-Chip Platform for Predictive Safety Assessment.

3D‐Bioprinting for Precision Microtissue Engineering: Advances, Applications, and Prospects

Bioactive scaffolds for tissue engineering: A review of decellularized extracellular matrix applications and innovations

Region-specific cellular and molecular basis of liver regeneration after acute pericentral injury

The role of altered lipid composition and distribution in liver fibrosis revealed by multimodal nonlinear optical microscopy

Non-invasive preeclampsia prediction using plasma cell-free RNA signatures.

Hepatic mitochondrial NAD+ transporter SLC25A47 activates AMPKα mediating lipid metabolism and tumorigenesis

Mobility-Modulated Sequential Dissociation Analysis Enables Structural Lipidomics in Mass Spectrometry Imaging.

基于类器官活库的肝胆精准诊疗新范式

Hepatic Organoid-Based High-Content Imaging Boosts Evaluation of Stereoisomerism-Dependent Hepatotoxicity of Stilbenes in Herbal Medicines

Lapatinib Suppresses HER2-Overexpressed Cholangiocarcinoma and Overcomes ABCB1– Mediated Gemcitabine Chemoresistance

Tandem Mass Spectrometry Imaging Enables High Definition for Mapping Lipids in Tissues.

Generation of multicellular tumor spheroids with micro-well array for anticancer drug combination screening based on a valuable biomarker of hepatocellular carcinoma

In-Vivo Monitoring of Liver Regeneration by Ultrasound Localization Microscopy: A Feasibility Study

sn-1 Specificity of Lysophosphatidylcholine Acyltransferase-1 Revealed by a Mass Spectrometry-Based Assay.

High-content imaging of human hepatic spheroids for researching the mechanism of duloxetine-induced hepatotoxicity

Co-administration of MDR1 and BCRP or EGFR/PI3K inhibitors overcomes lenvatinib resistance in hepatocellular carcinoma

Human primary epidermal organoids enable modeling of dermatophyte infections

Fibrinogen improves liver function via promoting cell aggregation and fibronectin assembly in hepatic spheroids

药物肝毒性评价体外细胞模型的相关研究进展

三维HepaRG细胞模型的建立及对曲格列酮肝毒性评价

Clinical characteristics of the recovered COVID-19 patients with re-detectable positive RNA test

The lncRNA XIST promotes proliferation, migration and invasion of gastric cancer cells by targeting miR-337.

Auto Micro Atomization Delivery of Human Epidermal Organoids Improves Therapeutic Effects for Skin Wound Healing

构建三阴性乳腺癌的三维体外培养模型用于抗肿瘤药物的活性评价

肝细胞外基质促进人胚胎干细胞肝向诱导分化的实验研究

小鼠胎肝细胞透明质酸3D培养体系的建立

异种(猪)脱细胞真皮基质粉对表皮细胞和成纤维细胞的促进作用

猪皮细胞外基质促进创伤小鼠再表皮化的实验研究

基于类器官3D培养和高内涵成像的药物肝毒性评价模型研究

基于类器官3D培养的何首乌易感物质肝毒性评价

小分子化合物诱导人胃上皮细胞直接转化为内胚层多潜能祖细胞

间充质干细胞无异源/无血清培养基研发的现状和前景

干细胞治疗糖尿病的研究现状及展望

Lgr5和CD44在肠息肉和结直肠癌中的表达及意义

无血清培养基SYL-SF对间充质干细胞的培养和扩增作用

临床研究用间充质干细胞的体外制备策略

不同浓度葡萄糖对人血管内皮细胞的影响

经体外预处理人胎儿骨髓间充质干细胞的潜在自身成瘤性

单克隆来源的小鼠胎肝HPP-CFC肝上皮分化潜能的研究

人羊水来源MSC的分离培养鉴定及其免疫抑制特性的初步研究

用慢病毒转染RNAi技术沉默胆固醇7α羟化酶的基因表达,降低肝细胞中胆汁酸的分泌

生物支架材料胶原膜交联前后的特性分析

大鼠肝移植急性排斥反应模型的建立与评价

腺病毒介导CTLA4Ig及CTLA4双基因在骨髓间充质干细胞中的表达

CTLA4基因修饰骨髓间充质干细胞向肝细胞诱导分化及其免疫抑制功能研究

静态单轴拉伸应变刺激对细胞有丝分裂方向的影响

siRNA沉默socs3对红系发育的影响

自体骨髓间充质干细胞为种子细胞构建组织工程化全层皮肤

慢病毒介导的稳定表达bFGF的胎儿肝脏基质细胞株的建立

胚胎干细胞：从基础到临床有多远

胆汁酸代谢对肝细胞功能的影响

胚胎干细胞自我复制及亚全能分化特性维持的分子机制

同种异体骨髓间充质干细胞心内膜移植治疗小型猪急性心肌梗死

肝细胞微囊化移植——肝病细胞治疗的新希望

人脂肪来源干细胞在模拟微重力环境中的生长特性

siRNA沉默HIF-1α对胎肝基质细胞SDF-1α表达的影响

神经元限制性沉默因子对人胰岛素基因转录调控作用的研究

表皮形态发生素(Epimorphin)与表皮形态发生

成体干细胞及其在再生医学中的应用

Wnt 3a在神经干细胞向多巴胺能神经元分化过程中作用的研究

一种改良帕金森大鼠模型的制作

组织工程血管研究现状

混合细胞共微囊化对肝细胞功能的支持作用