百晓学者学者目录

焦娜

博士生导师、教授、研究员，复旦大学

精选作品

期刊论文

2026

计算宏基因组学“三链驱动、四维融合”教学模式构建与实践

朱瑞新，焦娜，王寅炤，张国庆，赵国屏

《微生物学通报》

2026

Multi-kingdom profiling reveals altered gut phage-bacteria-metabolite interactions in MASLD

Xiaofeng Zhou, Da Zhou, Yan-Ni Pu, H. Kim, Zhong-Han Sun, Wenhao Qi, Jia-Dong Jin, Wanqin Zhang, Ming-Feng Xia, Cheng-Yan Wang, Shang-Yu Hong, L. Nguyen, Na Jiao, Yan Zheng, Tao-Tao Liu

Nature Communications

DOI

2026

IBDkb: an AI-enhanced integrative knowledge base for inflammatory bowel disease research and drug discovery

Liwen Tao, Shiqing Shi, Rui-Xin Zhu, Zhuo Liu, Bin Yang, Lei Liu, Wan-Ning Chen, Q. Long, Na Jiao, Guoqing Zhang, Ping-Ping Xu, Ding-Feng Wu

bioRxiv

DOI

2026

Mutant KRAS favors a microbe that signals back.

Na Jiao, Li-Xin Zhu, Rui-Xin Zhu

Cell Host and Microbe

DOI

2026

DeepSeMS: revealing the hidden biosynthetic potential of the global ocean microbiome with a large language model

Tingjun Xu, Yuwei Yang, Rui-Xin Zhu, Wei-Li Lin, Jixuan Li, Yan Zheng, Peng Zhang, Guoqing Zhang, Guoping Zhao, Na Jiao

Nature Computational Science

DOI

2026

Integrative multi-cohort analysis identifies urinary microbiota as non-invasive biomarkers of bladder cancer

Liwen Tao, Tingting Zhao, Yi-Yang Xu, Wan-Ning Chen, Xinyue Zhu, Y. Hao, Li-Xin Zhu, Na Jiao, Ming Cao, Xiao-Wen Pu, Rui-Xin Zhu

BMC Microbiology

DOI

2025

STAT1 mediates the pro-inflammatory role of GBP5 in colitis

Yichen Li, Wen-Xia Wang, Rui-Xin Zhu, Xinyue Zhu, Mingwei Sun, Yanlan Huang, Wan-Ning Chen, Sheng Gao, Na Jiao, Xu-Tao Lin, J. Ke, Tao Xu, Lin-Lin Hou, P. Lan, Li-Xin Zhu

Communications Biology

DOI

2025

Disrupted host-microbiota crosstalk promotes nonalcoholic fatty liver disease progression by impaired mitophagy

Wen-Jing Yin, Wen-Xing Gao, Yuwei Yang, Wei-Li Lin, Wan-Ning Chen, Xinyue Zhu, Rui-Xin Zhu, Li-Xin Zhu, Na Jiao

Microbiology spectrum

DOI

2025

Integrative multi-omics reveals microbial genomic variants driving altered host-microbe interactions in autism spectrum disorder

Wan-Ning Chen, Xinjun Wang, Rui-Xin Zhu, Wen-Xing Gao, Liwen Tao, Rong Yang, Qing Wei, Yi-Ming Zhang, Yujiao Gong, Hui Zhong, Linsheng Huang, Xinyue Zhu, Yuwei Yang, Linjuan Zhang, Lin Wan, Guangrui Yang, Yan Li, Na Jiao, Ji-Feng Wang, H. Qin, Li-Xin Zhu

Cell Reports Medicine

DOI

2025

Database resources of the National Genomics Data Center, China National Center for Bioinformation in 2026

Yiming Zhang Wenming Jingfa Shuhui Shunmin Guoqing Yixue Bao Zhang Zhao Xiao Song He Zhang Li Zhao Chen Wan, Yi-Ming Bao, Zhang Zhang, Wen-Ming Zhao, Jing-Fa Xiao, Shu-Hui Song, Shunmin He, Guo-Qing Zhang, Yi-Xue Li, Guo-Ping Zhao, Run-Sheng Chen, Yi-Bo Wang, Wei-Jie Zhang, Xiao-Ning Chen, Yanling Sun, Bixia Tang, Yu Zhang, Kai Liu, Bing Su, Yao-Xi He, Tingrui Song, Yirong Shi, Yan-Yan Li, Di Hao, Kaixin Zhan, Tao Xu, Wenyan Lei, Cui-Dan Li, Heng-Yu Zhou, Zhi Nie, Anke Wang, Pan Li, Pei-Han Wang, Zhuo-Jing Fan, Rong-Xi Zhu, Haoyu Cheng, Yu-Xian Guo, L. Yue, Xiao-Yuan Jiang, Renjun Gao, Yongjie Sheng, Haitao Niu, Tuohetaerbaike Bahetibieke, Wen-Bao Zhang, Fei Chen, Jia-Yue Meng, Meng-Yao Han, Yu-Wei Huang, Liyun Yuan, Ruikun Xue, Jing-Yao Zeng, Xi-Ni Meng, Qifei Wang, Yi-Wen Hu, Yulan Deng, Na Ai, Zheng Huang, Yun Li, Yang Yuan, Guo-Chao Li, Lan Jiang, Ting Li, L. Zuo, Jianxin Chen, Qianqian Peng, Si Wang, Si-Cheng Wu, Hao Jiang, Hai-Long Kang, Jia-Wei Shi, Nian-Guo Dong, Xi-Miao He, Fei Yang, Shuai Jiang, Zhen-Xian Han, X. Bai, Dong Zou, Si-Si Zhang, Yi Wang, Zhi-Jian Duan, Lun Li, Wenjing Sun, Si-Jia Zhang, Quan Luo, Jin-Ying Han, Hairong Huang, Adong Shen, Jing Wang, Hao Wen, Cong-Fan Bu, X. Ji, Qi-Heng Qian, Hao Zhang, Qingyun Cai, Kai-Wen Zhang, Xiao-Qing Jiang, Mingkun Li, Hong Luo, Zishan Wu, Siwei Ren, Haixia Xie, Zhixiang Yuan, Dongmei Tian, De-Mian Kong, Shao-Qi Bei, Yueyue Wu, Lei Liu, Su-Qi Cao, Weilin Lin, Rui-Xin Zhu, Dingfeng Wu, Yuyan Meng, Wan Liu, Ping-Ping Wang, Xin-Hao Zhuang, Xing Yan, Zhi-Hua Zhou, Wen-Xing Gao, Qiang Li, Na Jiao, Yi-Yun Liu, Lili Tian, Wei Zhao, Wenting Zong, Xinchang Zheng, Xu Chen, Tingting Chen, Xiao-Long Zhang, Yu-Bo Zhou, Jun-Wei Zhu, Bing Xu, Li-Li Dong, Cai-Xia Yu, Wenjie Li, S. Zhai, Yubin Sun, Qian Chen, Yan-Qing Wang, Xuetong Zhao, Shao-Sen Zhang, Jin-Biao Wang, Yuhao Zeng, Zheng Luo, Y. Zhan, Zi-Han Wang, Xi Zhao, Yu-Xin Liu, Lina Ma, Yingke Ma, Mei-Li Chen, Tong-Tong Zhu, Wenzhuo Cheng, Y. Chu, Ming Chen, Tian-Yi Xu, Hao Gao, Si Zheng, Jialin Mai, Jin-Bei Wang, R. Tang, Jiao Li, Yue Qi, Zhaohua Li, Zhuang Xiong, Xu-Peng Chen, Yaoke Wei, Xiangyu Yu, Rujiao Li, Mochen Zhang, Huiying Chen, Guo-Liang Wang, Song Wu, H. Qu, Xiang-Dong Fang, En-Hui Jin, Dongli Zhao, Gangao Wu, Zhong-Huang Wang, Zhiyao Wei, Zhe Zhang, Yuan-Guang Meng, Yong-Rong Cao, Xuemei Lu, Ya-Nan Wang, Wei Liu, Jinyan Huang, Yan-Fang Jiang, Guoyue Lv, Xin-Yu Liu, Guo-Wang Xu, Xu-Min Wang, Jiang-Yong Qu, Baisheng Li, Chang Zhang, Xiao-Feng Zou, Guo-Xi Zhang, You Guo, Wei-Wei Jin, J. Gong, Xiaohui Niu, Wen-Kang Shen, An-Yuan Guo, Zhixiang Zuo, Jian Ren, Xin-Xin Zhang, Yun Xiao, Xia Li, Dan Liu, Yu Xue, Zheng Zhao, Tao Jiang, Wanying Wu, Fangqing Zhao, Jin-Yang Zhang, Xian-Wen Meng, Bowen Song, Jia Meng, Yujie Gou, Miao-Miao Chen, Di Peng, Hao Luo, Feng Gao, Jie Jiang, Kun-Qi Chen, Xin-He Huang, Chi Zhang, Chun-Jie Liu, Guiyan Xie, Hao Yuan, Tian-Han Su, Yong E. Zhang, Chenfen Zhou, Yincong Zhou, Guo Guo, Qiong Zhang, Shanshan Fu, Miao-Ying Zhao, Tong Chen, Yuan Yuan, Dachao Tang, Ming Lei, M. Luo, Yubin Xie, Ya-Ru Miao, Jiongming Ma, Haokai Ye, Dai-Yun Huang, Yu-xin Zhang, Di Zhang, Jianzhen Peng, Xingyu Liao, Xin-Xin Gao, Jian-Xin Wang, Jiang Li, Chunhui Yuan, Dechang Yang, Feng Tian, Ge Gao, Wenyi Wu, Cheng Han, Juntian Qi, Ni A. An, Chuan-Yu Li, Xuan Wang, Zhen Wei, Xiao Luo, Jiaxing Yue, Zepu Miao, Qing Tang, Zihao Feng, Bo Liu, Jian Yang, Chen-Yu Yang, Leming Xiao

Nucleic Acids Research

DOI

2025

Multimodal Metagenomic Analysis Reveals Microbial InDels as Superior Biomarkers for Pediatric Crohn's Disease.

Mengping Shen, Sheng Gao, Rui-Xin Zhu, Wei Wang, Wen-Xing Gao, Liwen Tao, Wan-Ning Chen, Xinyue Zhu, Yuwei Yang, Ting-Jun Xu, Tingting Zhao, Na Jiao, M. Zhi, Li-Xin Zhu

Journal of Crohn's & Colitis

DOI

2024

Mo1775 MICROBIAL MULTI-DIMENSIONAL ANALYSES REVEAL BOTH BACTERIAL ABUNDANCE AND INDELS AS PROMISING NON-INVASIVE BIOMARKERS FOR PEDIATRIC CROHN'S DISEASE

Mengping Shen, Sheng Gao, Rui-Xin Zhu, Wan-Ning Chen, Li-Xin Zhu, Na Jiao

Gastroenterology

DOI

2024

Mo1776 FECAL METAPROTEOMICS-DERIVED HOST AND MICROBIAL PROTEINS SERVE AS SUPERIOR DIAGNOSTIC MARKERS FOR CROHN'S DISEASE

Sheng Gao, Liwen Tao, Rui-Xin Zhu, Tingting Zhao, Wan-Ning Chen, Mengping Shen, Na Jiao, Li-Xin Zhu

Gastroenterology

DOI

2024

Sa1866 ENHANCED MICROBIOTA PROFILING IN PATIENTS WITH QUIESCENT CROHN'S DISEASE THROUGH COMPARISON WITH PAIRED HEALTHY FIRST-DEGREE RELATIVES USING FECAL METAGENOMICS AND METABOLOMICS

Wan-Ning Chen, Yichen Li, Wen-Xia Wang, Sheng Gao, Ding-Feng Wu, Na Jiao, Ping Lan, M. Zhi, Li-Xin Zhu, Rui-Xin Zhu

Gastroenterology

DOI

2024

Mo1905 INTRATUMORAL MICROBIOME AS NOVEL INDICATORS AND THERAPEUTIC TARGETS IN GASTROINTESTINAL CANCER METASTASIS

Wen-Xing Gao, Liwen Tao, Rui-Xin Zhu, Tingting Zhao, Xinyue Zhu, Yuwei Yang, Li-Xin Zhu, Na Jiao

Gastroenterology

DOI

2024

Multi-kingdom microbial signatures in excess body weight colorectal cancer based on global metagenomic analysis

Xinyue Zhu, Ping-Ping Xu, Rui-Xin Zhu, Wen-Xing Gao, Wen-Jing Yin, Ping Lan, Li-Xin Zhu, Na Jiao

Communications Biology

DOI

2024

The search for authentic microbiome–disease relationships

Na Jiao, Li-Xin Zhu, Rui-Xin Zhu

Nature Medicine

DOI

2024

Sa1897 GBP5 INDUCES PRO-INFLAMMATORY INNATE LYMPHOID CELLS BY STIMULATING STAT1 ACTIVITY AND EXPRESSION

Yichen Li, Wen-Xia Wang, Rui-Xin Zhu, Xinyue Zhu, Sheng Gao, Na Jiao, Tao Xu, Lin-Lin Hou, Ping Lan, Li-Xin Zhu

Gastroenterology

DOI

2024

Identification and validation of microbial biomarkers from cross-cohort datasets using xMarkerFinder

Wen-Xing Gao, Wei-Li Lin, Qiang Li, Wan-Ning Chen, Wen-Jing Yin, Xinyue Zhu, Sheng Gao, Lei Liu, Wenjie Li, Ding-Feng Wu, Guoqing Zhang, Rui-Xin Zhu, Na Jiao

Nature Protocols

DOI

2024

Systematic identification of secondary bile acid production genes in global microbiome

Yuwei Yang, Wen-Xing Gao, Rui-Xin Zhu, Liwen Tao, Wan-Ning Chen, Xinyue Zhu, Mengping Shen, Ting-Jun Xu, Tingting Zhao, Xiao-Bo Zhang, Li-Xin Zhu, Na Jiao

bioRxiv

DOI

2023

Multimodal metagenomic analysis reveals microbial single nucleotide variants as superior biomarkers for early detection of colorectal cancer

Wen-Xing Gao, Xiang Gao, Li-Xin Zhu, Sheng Gao, Rui-Cong Sun, Zhong Feng, Ding-Feng Wu, Zhan-Cong Liu, Rui-Xin Zhu, Na Jiao

Gut microbes

DOI

2023

NAFLDkb: A Knowledge Base and Platform for Drug Development against Nonalcoholic Fatty Liver Disease

Tingjun Xu, Wen-Xing Gao, Li-Xin Zhu, Wan-Ning Chen, Chao-Qun Niu, Wen-Jing Yin, Liangxiao Ma, Xinyue Zhu, Yun-Chao Ling, Sheng Gao, Lei Liu, Na Jiao, Wei-Ming Chen, Guo-Qing Zhang, Rui-Xin Zhu, Ding-Feng Wu

Journal of Chemical Information and Modeling

DOI

2023

Integrative multi-omics deciphers the spatial characteristics of host-gut microbiota interactions in Crohn’s disease

Xiang Gao, Rui-Cong Sun, Na Jiao, Xiao Liang, Gengfeng Li, Han Gao, Xiaohan Wu, Mu-qing Yang, Chun-Qiu Chen, Xiao-Min Sun, Liang Chen, Wei Wu, Y. Cong, Rui-Xin Zhu, Tian-Nan Guo, Zhanju Liu

Cell Reports Medicine

DOI

2023

Microbial genes outperform species and SNVs as diagnostic markers for Crohn’s disease on multicohort fecal metagenomes empowered by artificial intelligence

Sheng Gao, Xiang Gao, Rui-Xin Zhu, Ding-Feng Wu, Zhong Feng, Na Jiao, Rui-Cong Sun, Wen-Xing Gao, Qing He, Zhan-Cong Liu, Li-Xin Zhu

Gut microbes

DOI

2023

Host-microbiota interactions contributing to the heterogeneous tumor microenvironment in colorectal cancer

Xiaoyi Li, Ding-Feng Wu, Qiuyu Li, Jinglan Gu, Wen-Xing Gao, Xinyue Zhu, Wen-Jing Yin, Rui-Xin Zhu, Li-Xin Zhu, Na Jiao

bioRxiv

DOI

2023

EP22 UNIQUE MICROBIAL ALTERATIONS AND SPECIFIC MULTI-KINGDOM BIOMARKERS OF OVERWEIGHT COLORECTAL CANCER

Xinyue Zhu, Rui-Xin Zhu, Wen-Xing Gao, Wen-Jing Yin, Li-Xin Zhu, Na Jiao

Gastroenterology

DOI

2023

EP114 DISTINCT PATTERNS OF HOST-MICROBE CROSSTALK IN THE PROGRESSION OF NONALCOHOLIC FATTY LIVER DISEASE

Wen-Jing Yin, Rui-Xin Zhu, Wen-Xing Gao, Xinyue Zhu, Li-Xin Zhu, Na Jiao

Gastroenterology

DOI

2023

EP165 UNIQUENESS OF HOST-MICROBIOTA MEDIATED HETEROGENEOUS TUMOR MICROENVIRONMENT AMONG CONSENSUS MOLECULAR SUBTYPES IN COLORECTAL CANCER

Xiaoyi Li, Ding-Feng Wu, Jianyu Lin, Wen-Xing Gao, Xinyue Zhu, Wen-Jing Yin, Rui-Xin Zhu, Li-Xin Zhu, Na Jiao

Gastroenterology

DOI

2023

EP166 THE PREDICTIVE ABILITY OF INTRATUMORAL MICROBIOME FOR COLORECTAL CANCER METASTASIS AND ITS ROLE IN TUMOR MICROENVIRONMENT

Wen-Xing Gao, Rui-Xin Zhu, Xinyue Zhu, Wen-Jing Yin, Li-Xin Zhu, Na Jiao

Gastroenterology

DOI

2023

Systematic Microbiome Dysbiosis Is Associated with IgA Nephropathy

Fengtao Cai, Chenfen Zhou, Na Jiao, Xin-Ling Liang, Zhi-Ming Ye, Wei Chen, Qiong-Qiong Yang, Hui Peng, Ying Tang, Chao-Qun Niu, Guo-Ping Zhao, Ze-Feng Wang, Guo-Qing Zhang, Xue-Qing Yu

Microbiology spectrum

DOI

2023

Erratum for Cai et al., “Systematic Microbiome Dysbiosis Is Associated with IgA Nephropathy”

Fengtao Cai, Chenfen Zhou, Na Jiao, Xin-Ling Liang, Zhiming Ye, Wei Chen, Qiong-Qiong Yang, Huie Peng, Ying Tang, Chaoqun Niu, Guoping Zhao, Zefeng Wang, Guoqing Zhang, Xue-Qing Yu

Microbiology spectrum

DOI

2022

Targeting keystone species helps restore the dysbiosis of butyrate‐producing bacteria in nonalcoholic fatty liver disease

Ding-Feng Wu, Lei Liu, Na Jiao, Yi-Da Zhang, Li Yang, Chuan Tian, P. Lan, Li-Xin Zhu, R. Loomba, Rui-Xin Zhu

iMeta

DOI

2022

Evidence challenging the causal role of gut microbiota in inflammatory bowel diseases

Na Jiao, Xiao Ke, Li-Xin Zhu, Rui-Xin Zhu

Gastroenterology Report

DOI

2022

1094: ARTIFICIAL INTELLIGENCE NON-INVASIVE DIAGNOSTIC TOOLS BASED ON MICROBIAL GENES ACHIEVE SUPERIOR DIAGNOSTIC ACCURACY FOR CROHN'S DISEASE

Sheng Gao, Xiang Gao, Rui-Xin Zhu, Ding-Feng Wu, Zhong Feng, Na Jiao, Rui-Cong Sun, Wen-Xing Gao, R. Zhao, Zhanju Liu, Li-Xin Zhu

Gastroenterology

DOI

2022

IBD Subtype-Regulators IFNG and GBP5 Identified by Causal Inference Drive More Intense Innate Immunity and Inflammatory Responses in CD Than Those in UC

Sheng Gao, Yichen Li, Ding-Feng Wu, Na Jiao, Li Yang, Rui Zhao, Zhifeng Xu, Wan-Ning Chen, Xu-Tao Lin, Sijing Cheng, Li-Xin Zhu, Ping Lan, Rui-Xin Zhu

Frontiers in Pharmacology

DOI

2022

Multi-kingdom microbiota analyses identify bacterial–fungal interactions and biomarkers of colorectal cancer across cohorts

Ning-Ning Liu, Na Jiao, Jingcong Tan, Zi-Liang Wang, Ding-Feng Wu, An-Jun Wang, Jie Chen, Liwen Tao, Chenfen Zhou, W. Fang, I. Cheong, W. Pan, W. Liao, Z. Kozlakidis, C. Heeschen, G. Moore, Li-Xin Zhu, Xingdong Chen, Guo-Qing Zhang, Rui-Xin Zhu, Hui Wang

Nature Microbiology

DOI

2022

Microbial multidimensional signature assessment reveals microbial SNVs as the superior non‐invasive biomarkers for early detection of colorectal cancer

Wen-Xing Gao, Rui-Cong Sun, Li-Xin Zhu, Sheng Gao, Zhong Feng, Ding-Feng Wu, Xiang Gao, R. Zhao, Ye Yao, Zhan-Ju Liu, Rui-Xin Zhu, Na Jiao

The FASEB Journal

DOI

2021

Microbiota in mesenteric adipose tissue from Crohn’s disease promote colitis in mice

Zhen He, Jinjie Wu, Junli Gong, J. Ke, Tao Ding, Wen-Jing Zhao, Wai-Ming Cheng, Zhan-peng Luo, Qilang He, Wanyi Zeng, Jing Yu, Na Jiao, Yanmin Liu, Bin Zheng, Lei Dai, M. Zhi, Xiao-Jian Wu, C. Jobin, P. Lan

Microbiome

DOI

2021

Altered gut microbiome in FUT2 loss-of-function mutants in support of personalized medicine for inflammatory bowel diseases.

Sijing Cheng, Jun-Qing Hu, Xian-Rui Wu, Ji-An Pan, Na Jiao, Yichen Li, Yi-Bo Huang, Xu-Tao Lin, Yi-Feng Zou, Yuan Chen, Li-Xin Zhu, M. Zhi, P. Lan

Journal of genetics and genomics = Yi chuan xue bao

DOI

2021

605 THE IMPACT OF FUT2 LOSS-OF-FUNCTION MUTATION ON THE PATHOGENESIS OF INFLAMMATORY BOWEL DISEASES MEDIATED BY THE GUT MICROBIOME

Sijing Cheng, Jun-Qing Hu, Xian-Rui Wu, Na Jiao, Yichen Li, Yi-Bo Huang, Xu-Tao Lin, Yi-Feng Zou, Li-Xin Zhu, M. Zhi, P. Lan

DOI

2021

Su492 GBP5 MEDIATES AN EARLY STEP OF INFLAMMATORY REACTIONS IN INFLAMMATORY BOWEL DISEASES

Yichen Li, Sijing Cheng, Yi-Bo Huang, Na Jiao, Xu-Tao Lin, Yi-Feng Zou, Li-Xin Zhu, Ping Lan

DOI

2021

Role of Guanylate‐binding Protein 5 in Colonic Inflammation

Yichen Li, Sijing Cheng, Yi-Bo Huang, Na Jiao, Xu-Tao Lin, Yi-Feng Zou, Li-Xin Zhu, P. Lan

The FASEB Journal

DOI

2021

Comprehensive microbiota alterations in IBD and improved diagnostic accuracy for IBD using multi‐kingdom microbial features

Sheng Gao, Na Jiao, Ding-Feng Wu, Rui-Xin Zhu, Li-Xin Zhu

The FASEB Journal

DOI

2021

Fusobacterium nucleatum, a reproducible microbial marker for CRC prescreening

Na Jiao, Rui-Xin Zhu, Ding-Feng Wu, P. Lan, Li-Xin Zhu

The FASEB Journal

DOI

2021

Unbalanced dietary patterns contribute to the pathogenesis of precocious puberty by affecting gut microbiota and host metabolites

Ying Wang, Ding-Feng Wu, Hongying Li, Xian-quan Liang, Na Jiao, Wen-Xing Gao, Lu Zhao, Han Yu, Qian Wang, Yongsheng Ge, Changying Zhao, Mei-Ling Huo, Ruifang Cao, Sheng Gao, Liwen Tao, Yun-Chao Ling, Ling-Nan Zhao, X. Lv, Yi Liu, Le-Hai Zhang, Hao-Kui Zhou, Guo-Qing Zhang, Guo-Ping Zhao, Lei Zhang, Rui-Xin Zhu, Z. Gai

bioRxiv

DOI

2021

Putative Familial Transmissible Bacteria of Various Body Niches Link with Home Environment and Children’s Immune Health

Lu Zhao, Wan-Ning Chen, Yongsheng Ge, X. Lv, Ying Wang, Han Yu, Yi Liu, Ding-Feng Wu, Na Jiao, Yuanqi Wu, Daqing Lv, Guo-Qing Zhang, Fu-Zhong Xue, Xiaohong Xu, Z. Gai, Rui-Xin Zhu, Lei Zhang, Guo-Ping Zhao

Microbiology spectrum

DOI

2020

Identification of microbial markers across populations in early detection of colorectal cancer

Yuanqi Wu, Na Jiao, Rui-Xin Zhu, Yi-Da Zhang, Ding-Feng Wu, An-Jun Wang, Sa Fang, Liwen Tao, Yichen Li, Sijing Cheng, Xiao-Sheng He, P. Lan, Chuan Tian, Ning-Ning Liu, Li-Xin Zhu

Nature Communications

DOI

2020

Tu1257 THE IMPACT OF FUT2 DEFICIENCY ON THE GUT MICROBIOME IN INFLAMMATORY BOWEL DISEASES

Sijing Cheng, Jun-Qing Hu, Xian-Rui Wu, Na Jiao, Yichen Li, Yi-Bo Huang, Rui-Xin Zhu, M. Zhi, Li-Xin Zhu, P. Lan

DOI

2020

Tu1252 DAMP MOLECULES NMI AND IFP35 MAY MEDIATE EARLY INFLAMMATORY EVENTS IN THE PATHOGENESIS OF INFLAMMATORY BOWEL DISEASES

Sijing Cheng, Na Jiao, Xu-Tao Lin, Yichen Li, Yi-Bo Huang, Yi-Feng Zou, Rui-Xin Zhu, Huan-Huan Liang, Ying-Fang Liu, Li-Xin Zhu, P. Lan

DOI

2020

FUT2 deficiency may influence the pathogenesis of inflammatory bowel diseases through gut microbiome

Sijing Cheng, Jun-Qing Hu, Xian-Rui Wu, Na Jiao, Yichen Li, Yi-Bo Huang, Rui-Xin Zhu, M. Zhi, Li-Xin Zhu, P. Lan

The FASEB Journal

DOI

2020

Su1092 CAUSAL INFERENCE ANALYSIS OF THE TRANSCRIPTOME IDENTIFIED DIFFERENTIAL INNATE IMMUNITY AND INFLAMMATORY PATHWAY BETWEEN CROHN'S DISEASE AND ULCERATIVE COLITIS

Sheng Gao, Na Jiao, Ding-Feng Wu, Wen-Xing Gao, Li-Xin Zhu, Rui-Xin Zhu, P. Lan

DOI

2020

Alterations in bile acid metabolizing gut microbiota and specific bile acid genes as a precision medicine to subclassify NAFLD

Na Jiao, R. Loomba, Zi-Huan Yang, Ding-Feng Wu, Sa Fang, R. Bettencourt, P. Lan, Rui-Xin Zhu, Li-Xin Zhu

bioRxiv

DOI

2020

Mo1463 ANALYSIS AND APPLICATION OF KEYSTONE SPECIES IN NONALCOHOLIC FATTY LIVER DISEASE BASED ON CAUSAL INFERENCE AND DYNAMIC INTERVENTION MODELING

Ding-Feng Wu, Sa Fang, Zi-Huan Yang, Na Jiao, Wen-Xing Gao, P. Lan, Rui-Xin Zhu, R. Loomba, Li-Xin Zhu

DOI

2020

NMI and IFP35 are key DAMP molecules in inflammatory bowel diseases

Sijing Cheng, Na Jiao, Xu-Tao Lin, Yichen Li, Yi-Bo Huang, S. Vermeire, Yi-Feng Zou, Rui-Xin Zhu, Huan-Huan Liang, Ying-Fang Liu, Li-Xin Zhu, P. Lan

The FASEB Journal

DOI

2020

Meta‐Analysis Reveals Gut Microbial Signatures in Colorectal Adenoma and A Link with Secondary Bile Acid Conversion

Yuanqi Wu, Na Jiao, Ding-Feng Wu, Sa Fang, Wen-Xing Gao, Xiao-Sheng He, Li-Xin Zhu, Rui-Xin Zhu

The FASEB Journal

DOI

2019

Gut microbiota contributes to the distinction between two traditional Chinese medicine syndromes of ulcerative colitis

Ya-Li Zhang, Liting Cai, Junyi Qi, Yunzheng Lin, Yan-Cheng Dai, Na Jiao, You-Lan Chen, Lie Zheng, Bei-Bei Wang, Li-Xin Zhu, Zhi-Peng Tang, Rui-Xin Zhu

World Journal of Gastroenterology

DOI

2019

Gut bacteria contributes to NAFLD pathogenesis by promoting secondary bile acids biosynthesis

Na Jiao, Ding-Feng Wu, Zi-Huan Yang, Sa Fang, Xiaoyi Li, Meifei Yuan, Rui-Xin Zhu, Li-Xin Zhu

The FASEB Journal

DOI

2019

Su1554 – Causal Inference Reveals that Clostridiales Species are Keystone Species in Nafld Pathogenesis

Ding-Feng Wu, Sa Fang, Zi-Huan Yang, Na Jiao, Yunzheng Lin, Xiaoyi Li, Jing Xiao, Meifei Yuan, Rui-Xin Zhu, Li-Xin Zhu

Gastroenterology

DOI

2019

317 – Gut Microbiota Contributes to Promoting Secondary Bile Acid Biosynthesis in Nafld Pathogenesis

Na Jiao, Ding-Feng Wu, Zi-Huan Yang, Sa Fang, Xiaoyi Li, Meifei Yuan, Rui-Xin Zhu, Li-Xin Zhu

Gastroenterology

DOI

2019

Keystone Species in the Pathogenic Process of NAFLD

Sa Fang, Ding-Feng Wu, Zi-Huan Yang, Na Jiao, Yunzheng Lin, Xiaoyi Li, Jing Xiao, Meifei Yuan, Rui-Xin Zhu, Li-Xin Zhu

The FASEB Journal

DOI

2019

Su1542 – Keystone Species in the Pathogenesis of Non-Alcoholic Fatty Liver Disease

Sa Fang, Ding-Feng Wu, Zi-Huan Yang, Na Jiao, Yunzheng Lin, Xiaoyi Li, Jing Xiao, Meifei Yuan, Rui-Xin Zhu, Li-Xin Zhu

Gastroenterology

DOI

2018

Gut microbiome may contribute to insulin resistance and systemic inflammation in obese rodents: a meta-analysis.

Na Jiao, S. Baker, C. Nugent, M. Tsompana, Liting Cai, Yong Wang, Michael J. Buck, R. Genco, R. Baker, Rui-Xin Zhu, Lixin Zhu

Physiological Genomics

DOI

2017

Suppressed hepatic bile acid signalling despite elevated production of primary and secondary bile acids in NAFLD

Na Jiao, S. Baker, A. Chapa‐Rodríguez, Wensheng Liu, C. Nugent, M. Tsompana, L. Mastrandrea, Michael J. Buck, R. Baker, R. Genco, Rui-Xin Zhu, Lixin Zhu

Gut

DOI

2017

AASLD Abstracts745 - Suppressed Hepatic Bile Acid Signaling Despite Elevated Production of Primary and Secondary Bile Acids in NAFLD

Na Jiao, S. Baker, A. Chapa‐Rodríguez, Wensheng Liu, C. Nugent, M. Tsompana, L. Mastrandrea, Michael J. Buck, R. Baker, R. Genco, Rui-Xin Zhu, Li-Xin Zhu

DOI

2017

High‐fat diet increases Clostridium clusters XIVa in obese rodents

Na Jiao, S. Baker, C. Nugent, M. Tsompana, Lingyu Guan, Yong Wang, Michael J. Buck, R. Genco, R. Baker, Rui-Xin Zhu, Lixin Zhu

The FASEB Journal

DOI

研究方向

微生物与宿主互作微生物资源挖掘微生物组学分析方法及平台开发

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