杨照罡｜吉林大学｜学者主页

2026

Intradermal Delivery of Catalase via Extracellular Vesicles for Targeted Photoaging Therapy

Pengcheng Zhang, Bo Pan, Jiayi Chen, Hao Jiang, Xinhe Wang, Yi-You Chen, Wei Wang, Ming Li, Qing-Yu Zeng, Zhaogang Yang

Biomaterials Research

DOI

2026

Tumor‐Associated Macrophages as Therapeutic Targets: Deciphering Interaction Networks and Advancing Clinical Translation

Wurihan Bao, Xiao-Jie Qu, Yi-Qi Wang, Dan Huang, Hui-Ling Zhang, Ming-Yuan Dong, Han Sun, Zhaogang Yang, Xue-Feng Li

MedComm

DOI

2026

Rewiring cellular immunotherapy: From CAR evolution to circuit innovations across diseases.

Jiayi Chen, Yaxin Cui, Keyi Du, Jiangshan Liu, Jing Xie, Si-Miao Wang, Zhaogang Yang

Biotechnology Advances

DOI

2026

Skeletal-muscle-targeted non-viral delivery of full-length DMD mRNA for Duchenne muscular dystrophy.

Yu Tian, Yutong Liu, Yuhao Tong, Kristin M. Huntoon, Liqun Yang, Junfeng Shi, Yi-Fan Ma, Shiyan Dong, Seongdong Jeong, Andreanne Poppy Estania, You Yi, K. J. Kwak, Yi-Fan Wang, Annette Wu, Jared L. Edwards, Xiao-Tian Wang, Yen-Tzu Chang, Jianhong Cao, Huan Zhang, Man Sun, Adam J. Grippin, Zhaogang Yang, Wen-jing Lu, L. Lee, Eman Bahrani, Hong-Jia Zhang, Long Bai, Patricia K Nguyen, Wen Jiang, Feng Lan, Betty Y. S. Kim, Andrew S Lee

Nature Biomedical Engineering

DOI

2025

Macrophage-centered therapy strategies: A promising weapon in cancer immunotherapy

Si-Miao Wang, Jiayi Liu, Yaxin Cui, Man Sun, Wei Wang, Jiayi Chen, Jing-Kai Gu, Zhaogang Yang

Asian Journal of Pharmaceutical Sciences

DOI

2025

Multifunctional extracellular vesicles inhibiting autophagy ameliorate immunotherapy in non-small cell lung cancer

Si-Miao Wang, Jiayi Chen, Yaxin Cui, Jian-Ming Xing, Jiayi Liu, Hao Jiang, Hongqun Yang, Huan Zhang, Man Sun, Jialin Li, Wei Liu, Zhou Chen, Wei Sun, Xiao-Bing Wang, Zhaogang Yang

Acta Pharmaceutica Sinica B

DOI

2025

Engineered exosomes for targeted microRNA delivery to reverse liver fibrosis.

Huan Zhang, Jian-Ming Xing, Man Sun, Yaxin Cui, Yu-Lai Li, Siyuan Hu, Xinhe Wang, Hao Jiang, Yun Zhang, Xuan-Jie Jiang, Fang Yang, Betty Y. S. Kim, Wen Jiang, Zhaogang Yang, Le-Sheng Teng

Biomaterials

DOI

2025

Immunological conversion of triple-negative breast cancer by engineered extracellular vesicle-mediated pyroptosis.

Huan Zhang, Man Sun, Jiayi Chen, Si-Miao Wang, Jiayi Liu, Hongqun Yang, Luotong Liu, Siyuan Hu, Fang Yang, Le-Sheng Teng, Zhou Chen, Xiao-Bing Wang, Shiyan Dong, Yi-Fan Ma, Jared L. Edwards, Xiao-Tian Wang, Yen-Tzu Chang, Betty Y. S. Kim, Wen Jiang, Yaxin Cui, Zhaogang Yang

Journal of Controlled Release

DOI

2025

Targeting Immune Checkpoints: Basic Signaling Pathways and Clinical Translation in Cancer Therapeutics

Han Sun, Dan Huang, Hui-Ling Zhang, Ming-Yuan Dong, Si-Miao Wang, Man Sun, Jiayi Liu, Yi-Qi Wang, Xiao-Jie Qu, Xue-Feng Li, Zhaogang Yang

MedComm - Oncology

DOI

2025

Allosteric targeted drug delivery for enhanced blood-brain barrier penetration via mimicking transmembrane domain interactions

Kaicheng Tang, Zhongjie Tang, Miaomiao Niu, Zuyin Kuang, Wei-Wei Xue, Xin-Yu Wang, Xin-Long Liu, Yang Yu, Seongdong Jeong, Yi-Fan Ma, Annette Wu, Betty Y. S. Kim, Wen Jiang, Zhaogang Yang, Chong Li

Nature Communications

DOI

2025

An Integrated Modular Vaccination System for Spatiotemporally Separated Perioperative Cancer Immunotherapy

Feiyan Gao, Xin-Long Liu, Zhongyi Ma, Mei Tang, Zhongjie Tang, Jin Wu, Min Luo, Yaqin Tang, Xiaoyou Wang, Bo-Chu Wang, Betty Y. S. Kim, Zhaogang Yang, Wen Jiang, Peng Tang, Chong Li

Advances in Materials

DOI

2025

In Situ Programming of the Tumor Microenvironment to Alleviate Immunosuppression for Pancreatic Cancer Immunotherapy

Man Sun, Huan Zhang, Ya-Rui Ma, Si-Miao Wang, Jiayi Chen, Yaxin Cui, Yun Zhang, Siyuan Hu, Dan Zhou, Pengcheng Zhang, Yahui Liu, Betty Y. S. Kim, Wen Jiang, Xiao-Bing Wang, Zhaogang Yang

Advancement of science

DOI

2025

Exosomes: a double‐edged sword in cancer immunotherapy

Jiayi Chen, Siyuan Hu, Jiayi Liu, Hao Jiang, Si-Miao Wang, Zhaogang Yang

MedComm

DOI

2025

LPAR4-targeted dual-loaded liposome for synergistic lung cancer therapy.

Si-Miao Wang, Hao Jiang, Jiayi Liu, Jiayi Chen, Siyuan Hu, Yaxin Cui, Xinhe Wang, Shaohan Sun, Jialin Li, Le-Sheng Teng, Jianan Shi, Wei Liu, Zhaogang Yang

European Journal of Pharmaceutical Sciences

DOI

2024

New avenues for cancer immunotherapy: Cell-mediated drug delivery systems.

Huan Zhang, Adam J. Grippin, Man Sun, Yi-Fan Ma, Betty Y. S. Kim, Le-Sheng Teng, Wen Jiang, Zhaogang Yang

Journal of Controlled Release

DOI

2024

Recent advances and clinical translation of liposomal delivery systems in cancer therapy.

Jiayi Chen, Siyuan Hu, Man Sun, Jianan Shi, Huan Zhang, Hong-Mei Yu, Zhaogang Yang

European Journal of Pharmaceutical Sciences

DOI

2024

Transdermal Delivery of Recombinant Human Growth Hormone by Liposomal Gel for Skin Photoaging Therapy.

Jiayi Chen, Siyuan Hu, Jingjing Zhang, Jiaxin Li, Jian-Ming Xing, Zhaogang Yang, Lesheng Teng

ACS Applied Bio Materials

DOI

2024

Regulation of cerebral blood flow boosts precise brain targeting of vinpocetine-derived ionizable-lipidoid nanoparticles

Xufei Bian, Ling Yang, Dingxi Jiang, Adam J. Grippin, Yi-Fan Ma, Shuang Wu, Lin-Ping Wu, Xiaoyou Wang, Zhongjie Tang, Kaicheng Tang, Weidong Pan, Shiyan Dong, Betty Y. S. Kim, Wen Jiang, Zhaogang Yang, Chong Li

Nature Communications

DOI

2024

Extracellular vesicles for breast cancer diagnosis and therapy

Jianan Shi, Huan Zhang, Yaxin Cui, Jian-Ming Xing, Wei Wang, Jiayi Chen, Si-Cong Wang, Zhaogang Yang

Extracellular Vesicle

DOI

2024

Extracellular Vesicles: A New Star for Gene Drug Delivery

Man Sun, Huan Zhang, Jiayi Liu, Jiayi Chen, Yaxin Cui, Simiao Wang, Xiangyu Zhang, Zhaogang Yang

International Journal of Nanomedicine

DOI

2023

Microfluidics for nano-drug delivery systems: From fundamentals to industrialization

Huan Zhang, Jie Yang, Rongze Sun, Songren Han, Zhaogang Yang, Lesheng Teng

Acta Pharmaceutica Sinica B

DOI

2023

Age-associated disparity in phagocytic clearance affects the efficacy of cancer nanotherapeutics

Yifan Wang, W. Deng, DaeYong Lee, Long Yan, Yi-Fei Lu, Shiyan Dong, Kristin M. Huntoon, A. Antony, Xue-Feng Li, R. Ye, Yan Zhao, Feiyan Zhao, B. Schrank, Jonghoon Ha, M. Kang, Mingming Yang, Ping Gong, P. Lorenzi, Lin Tan, Thomas D Gallup, Sarah K Tang, Zhaogang Yang, Jing Li, N. Sanford, Hong-Mei Wang, Betty Y. S. Kim, Wen Jiang

Nature Nanotechnology

DOI

2023

MiR-124-3p impedes the metastasis of non-small cell lung cancer via extracellular exosome transport and intracellular PI3K/AKT signaling

Qing Zhu, Yi-Xuan Zhang, Mo Li, Ying Zhang, Huan Zhang, Jiayi Chen, Zhao-Yang Liu, Peng Yuan, Zhaogang Yang, Xiaobing Wang

Biomarker Research

DOI

2023

Intradermally delivered mRNA-encapsulating extracellular vesicles for collagen-replacement therapy

Yi You, Yu Tian, Zhaogang Yang, Junfeng Shi, K. Kwak, Yuhao Tong, Andreanne Poppy Estania, Jianhong Cao, Wei-Hsiang Hsu, Yutong Liu, Chi-Ling Chiang, B. Schrank, Kristin M. Huntoon, DaeYong Lee, Ziwei Li, Yarong Zhao, Huan Zhang, Thomas D Gallup, Jonghoon Ha, Shiyan Dong, Xue-Feng Li, Yifan Wang, Wen-jing Lu, Eman Bahrani, L. Lee, Lesheng Teng, Wen Jiang, Feng Lan, Betty Y. S. Kim, Andrew S. Lee

Nature Biomedical Engineering

DOI

2023

Exosomes as smart drug delivery vehicles for cancer immunotherapy

Huan Zhang, Simiao Wang, Man Sun, Yaxin Cui, Jian-Min Xing, Lesheng Teng, Zhifang Xi, Zhaogang Yang

Frontiers in Immunology

DOI

2023

Adaptive design of mRNA-loaded extracellular vesicles for targeted immunotherapy of cancer

Shiyan Dong, Xuan Liu, Ye Bi, Yifan Wang, A. Antony, DaeYong Lee, Kristin M. Huntoon, Seongdong Jeong, Yifan Ma, Xue-Feng Li, W. Deng, B. Schrank, Adam J. Grippin, Jonghoon Ha, M. Kang, Mengyu Chang, Yarong Zhao, Rong-Ze Sun, Xiangshi Sun, Jie Yang, Jiayi Chen, Sarah K Tang, L. Lee, Andrew S Lee, Li-Rong Teng, Shengnian Wang, Le-Sheng Teng, Betty Y. S. Kim, Zhaogang Yang, Wen Jiang

Nature Communications

DOI

2022

Immunological conversion of solid tumours using a bispecific nanobioconjugate for cancer immunotherapy

Yi-Fei Lu, Kristin M. Huntoon, DaeYong Lee, Yifan Wang, Jonghoon Ha, Yaqing Qie, Xue-Feng Li, B. Schrank, Shiyan Dong, Thomas D Gallup, M. Kang, Haifeng Zhao, Y. An, Zhaogang Yang, Jing Li, Betty Y. S. Kim, Wen Jiang

Nature Nanotechnology

DOI

2022

Strategies of Perturbing Ion Homeostasis for Cancer Therapy

DaeYong Lee, Jonghoon Ha, M. Kang, Zhaogang Yang, Wen Jiang, Betty Y. S. Kim

Advances in Therapy

DOI

2022

Dual-Loaded Liposomes Tagged with Hyaluronic Acid Have Synergistic Effects in Triple-Negative Breast Cancer

Shiyan Dong, Ye Bi, Xiangshi Sun, Yarong Zhao, Rongze Sun, Fei Hao, Yating Sun, Yifan Wang, Xue-Feng Li, W. Deng, Xuan Liu, Jonghoon Ha, Li-Rong Teng, Ping Gong, Jing Xie, Betty Y. S. Kim, Zhaogang Yang, Wen Jiang, Le-Sheng Teng

Small

DOI

2022

Editorial: From Chronic Inflammation to Cancer: How Far Can Immunotherapy Go?

Xue-Feng Li, Lesheng Teng, Zhaogang Yang

Frontiers in Pharmacology

DOI

2021

Intelligent photothermal dendritic cells restart the cancer immunity cycle through enhanced immunogenic cell death.

Zhi-Hong Sun, Guan-Jun Deng, Xing-Hua Peng, Xiu-li Xu, Lanlan Liu, Jiaofeng Peng, Yi-Fan Ma, Pengfei Zhang, Austin Wen, Yifan Wang, Zhaogang Yang, P. Gong, Wen Jiang, Lin-Tao Cai

Biomaterials

DOI

2021

Advanced Immunotherapy Approaches for Glioblastoma

Yifan Ma, Zhaogang Yang, Kristin M. Huntoon, Wen Jiang, Betty Y. S. Kim

DOI

2021

Extracellular Vesicles in the Treatment of Parkinson's Disease: A Review.

Xiaoxia Yang, Yifan Ma, Haotian Xie, Shiyan Dong, G. Rao, Zhaogang Yang, Jingjing Zhang, Qingqing Wu

Current Medicinal Chemistry

DOI

2021

Self-Assembled pH-Sensitive Polymeric Nanoparticles for the Inflammation-Targeted Delivery of Cu/Zn-Superoxide Dismutase.

Xiangshi Sun, Kongtong Yu, Yulin Zhou, Shiyan Dong, Wen-Ji Hu, Yating Sun, Yu-Huan Li, Jing Xie, Robert J. Lee, Feng-Ying Sun, Yifan Ma, Shengnian Wang, Betty Y. S. Kim, Yifan Wang, Zhaogang Yang, Wen Jiang, You-Xin Li, Lesheng Teng

ACS Applied Materials and Interfaces

DOI

2021

Biomimetic Nanostructure Platform for Cancer Diagnosis Based on Tumor Biomarkers

Xi-Ping He, Yifan Ma, Haotian Xie, G. Rao, Zhaogang Yang, Jingjing Zhang, Zhong Feng

Frontiers in Bioengineering and Biotechnology

DOI

2021

Robust three-dimensional nanotube-in-micropillar array electrodes to facilitate size independent electroporation in blood cell therapy.

Xuan Liu, An-Yi Chang, Yifan Ma, Liping Hua, Zhaogang Yang, Shengnian Wang

Lab on a Chip

DOI

2021

Author Correction: Large-scale generation of functional mRNA-encapsulating exosomes via cellular nanoporation

Zhaogang Yang, Junfeng Shi, Jing Xie, Yifan Wang, Jing-Yao Sun, Tongzheng Liu, Yarong Zhao, Xiuting Zhao, Xin-Mei Wang, Yifan Ma, V. Malkoc, Chi-Ling Chiang, W. Deng, Yuanxin Chen, Yuan Fu, K. Kwak, Yamin Fan, Chen Kang, Chang-Cheng Yin, J. Rhee, P. Bertani, J. Otero, Wu Lu, Kyuson Yun, Andrew S. Lee, Wen Jiang, Lesheng Teng, Betty Y. S. Kim, L. Lee

Nature Biomedical Engineering

DOI

2021

Extracellular Vesicles: An Emerging Nanoplatform for Cancer Therapy

Yifan Ma, Shiyan Dong, Xue-Feng Li, Betty Y. S. Kim, Zhaogang Yang, Wen Jiang

Frontiers in Oncology

DOI

2020

Immunocyte Membrane-Coated Nanoparticles for Cancer Immunotherapy

P. Gong, Yifan Wang, Pengfei Zhang, Zhaogang Yang, W. Deng, Zhi-Hong Sun, Mingming Yang, Xue-Feng Li, Gongcheng Ma, Guan-Jun Deng, Shiyan Dong, Lin-Tao Cai, Wen Jiang

Cancers

DOI

2020

Nanotechnology and Microtechnology in Drug Delivery Systems

Jing-Yao Sun, Zhaogang Yang, Lesheng Teng

Dose-Response

DOI

2020

Core/shell PEGS/HA Hybrid Nanoparticle via Micelle-coordinated Mineralization for Tumor-specific Therapy.

Zihan Wu, Xiao-Yue Ma, Yifan Ma, Zhaogang Yang, Yuan Yuan, Chang-Sheng Liu

ACS Applied Materials and Interfaces

DOI

2020

Cell-Penetrating Peptides in Diagnosis and Treatment of Human Diseases: From Preclinical Research to Clinical Application

Jing Xie, Ye Bi, Huan Zhang, Shiyan Dong, Lesheng Teng, Robert J. Lee, Zhaogang Yang

Frontiers in Pharmacology

DOI

2020

Therapeutic modulation of phagocytosis in glioblastoma can activate both innate and adaptive antitumour immunity

Christina A. von Roemeling, Yifan Wang, Yaqing Qie, Hengfeng Yuan, Hai Zhao, Xiujie Liu, Zhaogang Yang, Mingming Yang, W. Deng, K. A. Bruno, Charles K. F. Chan, Andrew S. Lee, S. Rosenfeld, Kyuson Yun, Aaron J. Johnson, D. Mitchell, Wen Jiang, Betty Y. S. Kim

Nature Communications

DOI

2020

Microfluidic Electroporation Coupling Pulses of Nanoseconds and Milliseconds to Facilitate Rapid Uptake and Enhanced Expression of DNA in Cell Therapy

An-Yi Chang, Xuan Liu, Hong Tian, Liping Hua, Zhaogang Yang, Shengnian Wang

Scientific Reports

DOI

2019

Nanotechnology platforms for cancer immunotherapy.

Zhaogang Yang, Yifan Ma, Hai Zhao, Yuan Yuan, Betty Y. S. Kim

Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology

DOI

2019

Large-scale generation of functional mRNA-encapsulating exosomes via cellular nanoporation

Zhaogang Yang, Junfeng Shi, Jing Xie, Yifan Wang, Jing-Yao Sun, Tongzheng Liu, Yarong Zhao, Xiuting Zhao, Xin-Mei Wang, Yifan Ma, V. Malkoc, Chi-Ling Chiang, W. Deng, Yuanxin Chen, Yuan Fu, K. Kwak, Yamin Fan, Chen Kang, C. Yin, J. Rhee, P. Bertani, J. Otero, Wu Lu, Kyuson Yun, Andrew S. Lee, Wen Jiang, Lesheng Teng, Betty Y. S. Kim, L. Lee

Nature Biomedical Engineering

DOI

2019

Polyethylenimine-based formulations for delivery of oligonucleotides.

Fei Hao, Yu-Huan Li, Jing Zhu, Jing-Yao Sun, B. Marshall, Robert J. Lee, Lesheng Teng, Zhaogang Yang, Jing Xie

Current Medicinal Chemistry

DOI

2019

Folate Receptor-Targeted Albumin Nanoparticles Based on Microfluidic Technology to Deliver Cabazitaxel

Fanchao Meng, Yating Sun, Robert J. Lee, Guiyuan Wang, Xiaolong Zheng, Huan Zhang, Yige Fu, Guo-Jun Yan, Yifan Wang, W. Deng, Emily Parks, Betty Y. S. Kim, Zhaogang Yang, Wen Jiang, Lesheng Teng

Cancers

DOI

2019

Membrane TLR9 Positive Neutrophil Mediated MPLA Protects Against Fatal Bacterial Sepsis

Zhaogang Yang, Luo-Wei Wang, Hong-Mei Yu, Ruo-Nan Wang, Y. Gou, Mingming Zhang, Chen Kang, Tongzheng Liu, Yu Lan, Xiao-Bing Wang, Ji-Wei Liu, Merideth A. Cooper, Xin Li, K. Yue, Yongli Yu, Li-Ying Wang, Betty Y. S. Kim, Wen Jiang, Wei Sun

Theranostics

DOI

2019

Therapeutic Remodeling of the Tumor Microenvironment Enhances Nanoparticle Delivery

Yuanxin Chen, Xiujie Liu, Hengfeng Yuan, Zhaogang Yang, Christina A. von Roemeling, Yaqing Qie, Hai Zhao, Yifan Wang, Wen Jiang, Betty Y. S. Kim

Advancement of science

DOI

2018

Recent Progress in Metal-Based Nanoparticles Mediated Photodynamic Therapy

Jing-Yao Sun, S. Kormakov, Ying Liu, Yao Huang, Daming Wu, Zhaogang Yang

Molecules

DOI

2018

Extracellular mRNA detected by molecular beacons in tethered lipoplex nanoparticles for diagnosis of human hepatocellular carcinoma

Xin-Mei Wang, Kwang Joo Kwak, Zhaogang Yang, Ai-Li Zhang, Xiao-Li Zhang, Rachael Sullivan, D. Lin, R. Lee, Carlos E. Castro, K. Ghoshal, Carl Schmidt, L. Lee

PLoS ONE

DOI

2018

The Effect of Photothermal Therapy on Osteosarcoma With Polyacrylic Acid–Coated Gold Nanorods

Su Pan, Hong-Cun Xing, Xuqi Fu, Hong-Mei Yu, Zhaogang Yang, Yu-Dan Yang, Wei Sun

Dose-Response

DOI

2018

Nanocrystals: The Preparation, Precise Control and Application Toward the Pharmaceutics and Food Industry.

Cao Wu, Zhou Chen, Ya Hu, Zhiyuan Rao, Wangping Wu, Zhaogang Yang

Current pharmaceutical design

DOI

2018

A Review on Electroporation-Based Intracellular Delivery

Junfeng Shi, Yifan Ma, Jing Zhu, Yuanxin Chen, Yating Sun, Yicheng Yao, Zhaogang Yang, Jing Xie

Molecules

DOI

2017

The Advances of Carbon Nanotubes in Cancer Diagnostics and Therapeutics

Zhou Chen, Ai-Li Zhang, Xiao-Bing Wang, Jing Zhu, Yamin Fan, Hong-bo Yu, Zhaogang Yang

DOI

2017

Integration of Novel Materials and Advanced Genomic Technologies into New Vaccine Design.

W. Liao, Tian-Tian Zhang, Li-Qian Gao, Su Seong Lee, Jie Xu, Han Zhang, Zhaogang Yang, Zhao-Yu Liu, Wen Li

Current Topics in Medicinal Chemistry

DOI

2016

Electrospun nanofibers for cancer diagnosis and therapy.

Zhou Chen, Zhaofeng Chen, Ai-Li Zhang, Jia-Ming Hu, Xin-Mei Wang, Zhaogang Yang

Biomaterials Science

DOI

2016

Functional exosome-mimic for delivery of siRNA to cancer: in vitro and in vivo evaluation.

Zhaogang Yang, Jing Xie, Jing Zhu, Chen Kang, Chi-Ling Chiang, Xin-Mei Wang, Xiao-Bing Wang, Tai-Rong Kuang, Feng Chen, Zhou Chen, Ai-Li Zhang, Bo Yu, Robert J. Lee, Lesheng Teng, L. Lee

Journal of Controlled Release

DOI

2016

Delivery of Nanoparticles for Treatment of Brain Tumor.

Chen Kang, Yuan Sun, Jing Zhu, Wen Li, Ai-Li Zhang, Tai-Rong Kuang, Jing Xie, Zhaogang Yang

Current drug metabolism

DOI

2016

3D nanochannel electroporation for high-throughput cell transfection with high uniformity and dosage control.

Ling-Qian Chang, P. Bertani, D. Gallego-Perez, Zhaogang Yang, Feng Chen, Chi-Ling Chiang, V. Malkoc, Tai-Rong Kuang, Keliang Gao, L. Lee, Wu Lu

Nanoscale

DOI

2016

Extracellular mRNA Detected by Tethered Lipoplex Nanoparticle Biochip for Lung Adenocarcinoma Detection.

L. Lee, Zhaogang Yang, Mohammad A. Rahman, Junyu Ma, Kwang Joo Kwak, J. McElroy, K. Shilo, C. Goparaju, Lianbo Yu, W. Rom, Taek-Kyun Kim, Xiaogang Wu, Yu-Qing He, Kai Wang, H. Pass, S. Patrick Nana-Sinkam

American Journal of Respiratory and Critical Care Medicine

DOI

2016

癌治療における植物化学物質のデリバリーのためのナノテクノロジー【Powered by NICT】

Jing Xie, Zhaogang Yang, Chenguang Zhou, Jing Zhu, J. Robert, Lesheng Teng

2016

Delivery System of CpG Oligodeoxynucleotides through Eliciting an Effective T cell Immune Response against Melanoma in Mice

Wei Sun, Ming-Li Fang, Yajing Chen, Zhaogang Yang, Yue Xiao, M. Wan, Hua Wang, Yongli Yu, Li-Ying Wang

Journal of Cancer

DOI

2016

Nanoscale bio-platforms for living cell interrogation: current status and future perspectives.

Ling-Qian Chang, Jia-Ming Hu, Feng Chen, Zhou Chen, Jun-Feng Shi, Zhaogang Yang, Yi-Wen Li, L. Lee

Nanoscale

DOI

2016

Application of DODMA and Derivatives in Cationic Nanocarriers for Gene Delivery

Zhou Chen, Ai-Li Zhang, Zhaogang Yang, Xin-Mei Wang, Ling-Qian Chang, Zhao-Feng Chen, L. Lee

DOI

2016

Recent Progress in Dendrimer-based Gene Delivery Systems

Tai-Rong Kuang, Da-Jiong Fu, Ling-Qian Chang, Zhaogang Yang, Zhou Chen, Liliang Jin, Feng Chen, Xiang-Fang Peng

DOI

2016

Nanotechnology for the delivery of phytochemicals in cancer therapy.

Jing Xie, Zhaogang Yang, Chenguang Zhou, Jing Zhu, Robert J. Lee, Lesheng Teng

Biotechnology Advances

DOI

2016

癌へのsiRNAのデリバリーに対する機能的エクソソーム類似物:in vitroとin vivoでの評価

Zhaogang Yang, Jing Xie, Jing Zhu, Chen Kang, Chi-Ling Chiang, Xin-Mei Wang, Xiao-Bing Wang, Tai-Rong Kuang, Feng Chen, Zhou Chen, Ai-Li Zhang, Bo Yu, J. Robert, Lesheng Teng, L. L. James

2015

A Novel Isoquinoline Derivative Anticancer Agent and Its Targeted Delivery to Tumor Cells Using Transferrin-Conjugated Liposomes

Xue-Wei Yang, Shuang Yang, Hong-Yu Chai, Zhaogang Yang, Robert J. Lee, Weiwei Liao, Lesheng Teng

PLoS ONE

DOI

2015

Synthesis and drug delivery of mesoporous silica nanoparticles for cancer therapy

Zhou Chen, Cao Wu, Yong Yang, Jun-Feng Shi, Jia-Ming Hu, Zhaogang Yang, Zhaofeng Chen

DOI

2015

Micro-/nano-electroporation for active gene delivery.

Zhaogang Yang, Ling-Qian Chang, Chi-Ling Chiang, L. Lee

Current pharmaceutical design

DOI

2015

Magnetic Tweezers-based 3D Microchannel Electroporation for Efficient Cell Manipulation and High-Throughput Gene Transfection

J. Byrd, Zhaogang Yang, Wei-Ching Liao, N. Muthusamy, L. Lee, Chi-Ling Chiang, D. Gallego-Perez, M. Howdyshell, Wu Lu, Ling-Qian Chang

2015

Dielectrophoresis-assisted 3D nanoelectroporation for non-viral cell transfection in adoptive immunotherapy.

Ling-Qian Chang, D. Gallego-Perez, Xi Zhao, P. Bertani, Zhaogang Yang, Chi-Ling Chiang, V. Malkoc, Junfeng Shi, C. Sen, Lynn Odonnell, Jian-Hua Yu, Wu Lu, L. Lee

Lab on a Chip

DOI

2015

Novel biomaterials and biotechnology for nanomedicine

Zhaogang Yang, Ling-Qian Chang, Wenliang Li, Jin-Bing Xie

DOI

2015

Recent Organic and Inorganic Nanoparticles as Carriers for Drug Delivery

Jia-Ming Hu, Sanjun Fan, Zhou Chen, Ling-Qian Chang, Ai-Li Zhang, Xin-Mei Wang, Yushen Huang, Zhaogang Yang, Christopher J. Easley

DOI

2014

Insight into Mechanisms of Cellular Uptake of Lipid Nanoparticles and Intracellular Release of Small RNAs

Bo Yu, Xin-Mei Wang, Chenguang Zhou, Lesheng Teng, Wei Ren, Zhaogang Yang, Chih-Hsin Shih, Tianyou Wang, Robert J. Lee, Suoqin Tang, L. Lee

Pharmaceutical Research

DOI

2014

Targeted delivery of tumor suppressor microRNA-1 by transferrin-conjugated lipopolyplex nanoparticles to patient-derived glioblastoma stem cells.

Xin-Mei Wang, Xiaomeng Huang, Zhaogang Yang, D. Gallego-Perez, Junyu Ma, Xi Zhao, Jing Xie, I. Nakano, L. Lee

Current Pharmaceutical Biotechnology

DOI

2014

Nanomedicine based on nucleic acids: pharmacokinetic and pharmacodynamic perspectives.

Chenguang Zhou, Zhaogang Yang, Lesheng Teng

Current Pharmaceutical Biotechnology

DOI

2014

A microfluidic method for synthesis of transferrin-lipid nanoparticles loaded with siRNA LOR-1284 for therapy of acute myeloid leukemia

Zhaogang Yang, Bo Yu, Jing Zhu, Xiaomeng Huang, Jing Xie, Songlin Xu, Xiaojuan Yang, Xin-Mei Wang, Bryant C. Yung, L. Lee, Robert J. Lee, Lesheng Teng

Nanoscale

DOI

2014

Magnetic Tweezers-based 3D Microchannel Electroporation for High-Throughput Gene Transfection in Living Cells

Ling-Qian Chang, M. Howdyshell, Wei-Ching Liao, Chi-Ling Chiang, D. Gallego-Perez, Zhaogang Yang, Wu Lu, John C. Byrd, N. Muthusamy, L. Lee, R. Sooryakumar

Small

DOI

2013

A Polyethylenimine-Linoleic Acid Conjugate for Antisense Oligonucleotide Delivery

Jing Xie, Lesheng Teng, Zhaogang Yang, Chenguang Zhou, Yang Liu, Bryant C. Yung, Robert J. Lee

BioMed Research International

DOI

精选作品

期刊论文

Intradermal Delivery of Catalase via Extracellular Vesicles for Targeted Photoaging Therapy

Tumor‐Associated Macrophages as Therapeutic Targets: Deciphering Interaction Networks and Advancing Clinical Translation

Rewiring cellular immunotherapy: From CAR evolution to circuit innovations across diseases.

Skeletal-muscle-targeted non-viral delivery of full-length DMD mRNA for Duchenne muscular dystrophy.

Macrophage-centered therapy strategies: A promising weapon in cancer immunotherapy

Multifunctional extracellular vesicles inhibiting autophagy ameliorate immunotherapy in non-small cell lung cancer

Engineered exosomes for targeted microRNA delivery to reverse liver fibrosis.

Immunological conversion of triple-negative breast cancer by engineered extracellular vesicle-mediated pyroptosis.

Targeting Immune Checkpoints: Basic Signaling Pathways and Clinical Translation in Cancer Therapeutics

Allosteric targeted drug delivery for enhanced blood-brain barrier penetration via mimicking transmembrane domain interactions

An Integrated Modular Vaccination System for Spatiotemporally Separated Perioperative Cancer Immunotherapy

In Situ Programming of the Tumor Microenvironment to Alleviate Immunosuppression for Pancreatic Cancer Immunotherapy

Exosomes: a double‐edged sword in cancer immunotherapy

LPAR4-targeted dual-loaded liposome for synergistic lung cancer therapy.

New avenues for cancer immunotherapy: Cell-mediated drug delivery systems.

Recent advances and clinical translation of liposomal delivery systems in cancer therapy.

Transdermal Delivery of Recombinant Human Growth Hormone by Liposomal Gel for Skin Photoaging Therapy.

Regulation of cerebral blood flow boosts precise brain targeting of vinpocetine-derived ionizable-lipidoid nanoparticles

Extracellular vesicles for breast cancer diagnosis and therapy

Extracellular Vesicles: A New Star for Gene Drug Delivery

Microfluidics for nano-drug delivery systems: From fundamentals to industrialization

Age-associated disparity in phagocytic clearance affects the efficacy of cancer nanotherapeutics

MiR-124-3p impedes the metastasis of non-small cell lung cancer via extracellular exosome transport and intracellular PI3K/AKT signaling

Intradermally delivered mRNA-encapsulating extracellular vesicles for collagen-replacement therapy

Exosomes as smart drug delivery vehicles for cancer immunotherapy

Adaptive design of mRNA-loaded extracellular vesicles for targeted immunotherapy of cancer

Immunological conversion of solid tumours using a bispecific nanobioconjugate for cancer immunotherapy

Strategies of Perturbing Ion Homeostasis for Cancer Therapy

Dual-Loaded Liposomes Tagged with Hyaluronic Acid Have Synergistic Effects in Triple-Negative Breast Cancer

Editorial: From Chronic Inflammation to Cancer: How Far Can Immunotherapy Go?

Intelligent photothermal dendritic cells restart the cancer immunity cycle through enhanced immunogenic cell death.

Advanced Immunotherapy Approaches for Glioblastoma

Extracellular Vesicles in the Treatment of Parkinson's Disease: A Review.

Self-Assembled pH-Sensitive Polymeric Nanoparticles for the Inflammation-Targeted Delivery of Cu/Zn-Superoxide Dismutase.

Biomimetic Nanostructure Platform for Cancer Diagnosis Based on Tumor Biomarkers

Robust three-dimensional nanotube-in-micropillar array electrodes to facilitate size independent electroporation in blood cell therapy.

Author Correction: Large-scale generation of functional mRNA-encapsulating exosomes via cellular nanoporation

Extracellular Vesicles: An Emerging Nanoplatform for Cancer Therapy

Immunocyte Membrane-Coated Nanoparticles for Cancer Immunotherapy

Nanotechnology and Microtechnology in Drug Delivery Systems

Core/shell PEGS/HA Hybrid Nanoparticle via Micelle-coordinated Mineralization for Tumor-specific Therapy.

Cell-Penetrating Peptides in Diagnosis and Treatment of Human Diseases: From Preclinical Research to Clinical Application

Therapeutic modulation of phagocytosis in glioblastoma can activate both innate and adaptive antitumour immunity

Microfluidic Electroporation Coupling Pulses of Nanoseconds and Milliseconds to Facilitate Rapid Uptake and Enhanced Expression of DNA in Cell Therapy

Nanotechnology platforms for cancer immunotherapy.

Large-scale generation of functional mRNA-encapsulating exosomes via cellular nanoporation

Polyethylenimine-based formulations for delivery of oligonucleotides.

Folate Receptor-Targeted Albumin Nanoparticles Based on Microfluidic Technology to Deliver Cabazitaxel

Membrane TLR9 Positive Neutrophil Mediated MPLA Protects Against Fatal Bacterial Sepsis

Therapeutic Remodeling of the Tumor Microenvironment Enhances Nanoparticle Delivery

Recent Progress in Metal-Based Nanoparticles Mediated Photodynamic Therapy

Extracellular mRNA detected by molecular beacons in tethered lipoplex nanoparticles for diagnosis of human hepatocellular carcinoma

The Effect of Photothermal Therapy on Osteosarcoma With Polyacrylic Acid–Coated Gold Nanorods

Nanocrystals: The Preparation, Precise Control and Application Toward the Pharmaceutics and Food Industry.

A Review on Electroporation-Based Intracellular Delivery

The Advances of Carbon Nanotubes in Cancer Diagnostics and Therapeutics

Integration of Novel Materials and Advanced Genomic Technologies into New Vaccine Design.

Electrospun nanofibers for cancer diagnosis and therapy.

Functional exosome-mimic for delivery of siRNA to cancer: in vitro and in vivo evaluation.

Delivery of Nanoparticles for Treatment of Brain Tumor.

3D nanochannel electroporation for high-throughput cell transfection with high uniformity and dosage control.

Extracellular mRNA Detected by Tethered Lipoplex Nanoparticle Biochip for Lung Adenocarcinoma Detection.

癌治療における植物化学物質のデリバリーのためのナノテクノロジー【Powered by NICT】

Delivery System of CpG Oligodeoxynucleotides through Eliciting an Effective T cell Immune Response against Melanoma in Mice

Nanoscale bio-platforms for living cell interrogation: current status and future perspectives.

Application of DODMA and Derivatives in Cationic Nanocarriers for Gene Delivery

Recent Progress in Dendrimer-based Gene Delivery Systems

Nanotechnology for the delivery of phytochemicals in cancer therapy.

癌へのsiRNAのデリバリーに対する機能的エクソソーム類似物:in vitroとin vivoでの評価

A Novel Isoquinoline Derivative Anticancer Agent and Its Targeted Delivery to Tumor Cells Using Transferrin-Conjugated Liposomes

Synthesis and drug delivery of mesoporous silica nanoparticles for cancer therapy

Micro-/nano-electroporation for active gene delivery.

Magnetic Tweezers-based 3D Microchannel Electroporation for Efficient Cell Manipulation and High-Throughput Gene Transfection

Dielectrophoresis-assisted 3D nanoelectroporation for non-viral cell transfection in adoptive immunotherapy.

Novel biomaterials and biotechnology for nanomedicine

Recent Organic and Inorganic Nanoparticles as Carriers for Drug Delivery

Insight into Mechanisms of Cellular Uptake of Lipid Nanoparticles and Intracellular Release of Small RNAs

Targeted delivery of tumor suppressor microRNA-1 by transferrin-conjugated lipopolyplex nanoparticles to patient-derived glioblastoma stem cells.