刘宝辉｜广州大学｜学者主页

2026

大豆GmbHLH119和GmbHLH120基因生物信息学及表达模式分析

魏瑾，廖春梅，高丽诗，张莹，杨慧，岳琳，刘宝辉，陈丽玉

《作物学报》

2026

杨家慧，黄乐香，刘郅贤，苏伯鸿，赵苗羽，邢程顺，刘宝辉，赵晓晖

《植物遗传资源学报》

2025

矮秆基因在大豆育种中的研究进展

赵晓晖，赵苗羽，何佳薇，黄乐香，刘宝辉

《广东农业科学》

DOI

2025

The Crop Journal

DOI

2023

杨璧泽，刘宝辉，汤杨

《大豆科学》

2022

黎永力，杜浩，李泰，甘卓然，侯智红，董利东，刘宝辉，程群

《植物遗传资源学报》

DOI

2021

大豆BBX32基因生物信息学分析及基因编辑靶点设计

李泰，杜浩，黎永力，程玉汉，南海洋，侯智红，程群，刘宝辉

《大豆科学》

2021

大豆phyA下游基因预测和表达分析及敲除载体构建

张婷，马丽欣，刘俊，林晓雅，刘宝辉

《大豆科学》

2021

Oncology Report

DOI

2019

田志喜，刘宝辉，杨艳萍，李明，姚远，任小波，薛勇彪

《中国科学院院刊》，Vol. 33, No. 9

下载原文

2018

Molecular mechanisms involved in angiogenesis and potential target of antiangiogenesis in human glioblastomas

Yang Xu, Fan'en Yuan, Qianxue Chen, Bao-Hui Liu

DOI

2018

脑脊液 MGMT 启动子甲基化在胶质瘤诊断中的应用

Long Wang, Cai-Fei Huang, Jian Ge, Zhi-Biao Chen, Q. Cai, Bao-Hui Liu, Qianxue Chen

DOI

2018

PI3Kβ inhibitor AZD6482 exerts antiproliferative activity and induces apoptosis in human glioblastoma cells

Peng-Fei Xu, Ji-An Yang, Jun-Hui Liu, Xue Yang, Jianming Liao, Fan'en Yuan, Bao-Hui Liu, Qian-Xue Chen

Oncology Report

DOI

2018

Expression of Ferritin Light Chain (FTL) Is Elevated in Glioblastoma, and FTL Silencing Inhibits Glioblastoma Cell Proliferation via the GADD45/JNK Pathway

Ting-Feng Wu, Yun-Tao Li, Bao-Hui Liu, Shen-Qi Zhang, Li-Quan Wu, Xiao-Nan Zhu, Qianxue Chen

PLoS ONE

DOI

Long Wang, Qianxue Chen, Zhi-Biao Chen, Daofeng Tian, Haitao Xu, Q. Cai, Bao-Hui Liu, G. Deng

International Journal of Clinical and Experimental Pathology

2015

Association between X-ray repair cross-complementing group 1 gene polymorphisms and glioma risk: a systematic review and meta-analysis based on 22 case-control studies.

Ji-Qiang Li, Qianxue Chen, Bao-Hui Liu, Ji'an Yang, L. Shao, Ting-Feng Wu

International Journal of Clinical and Experimental Medicine

2015

Puerarin inhibits proliferation and induces apoptosis in human glioblastoma cell lines.

Ji-An Yang, Ji-Qiang Li, L. Shao, Qian Yang, Bao-Hui Liu, Ting-Feng Wu, Peng Wu, W. Yi, Qian-Xue Chen

International Journal of Clinical and Experimental Medicine

2015

人 Smad 4 基因在胶质瘤细胞中的作用研究

Qiang Cai, Qianxue Chen, Daofeng Tian, Bao-Hui Liu, Ming-Chang Li, Jun-Min Wang, Hui-Min Dong, Shen-Qi Zhang

DOI

2015

LRIG1, human EGFR inhibitor, reverses multidrug resistance through modulation of ABCB1 and ABCG2.

Bao-Hui Liu, Zhen-Tao Guo, Hui-Min Dong, Daofeng Tian, Qiang Cai, Bao-Wei Ji, Shen-Qi Zhang, Li-Quan Wu, Jun-Min Wang, Long Wang, Xiao-Nan Zhu, Yue Liu, Qianxue Chen

Brain Research

DOI

2015

Telomerase reverse transcriptase (TERT) rs2736100 polymorphism contributes to increased risk of glioma: evidence from a meta-analysis.

Ze-Sheng Peng, Daofeng Tian, Qianxue Chen, Shen-Qi Zhang, Bao-Hui Liu, Bao-Wei Ji

International Journal of Clinical and Experimental Medicine

2015

LRIG1 enhances the radiosensitivity of radioresistant human glioblastoma U251 cells via attenuation of the EGFR/Akt signaling pathway.

Ji-An Yang, Bao-Hui Liu, L. Shao, Zhen-Tao Guo, Qian Yang, Li-Quan Wu, Bao-Wei Ji, Xiao-Nan Zhu, Shen-Qi Zhang, Cheng-Jun Li, Qian-Xue Chen

International Journal of Clinical and Experimental Pathology

2015

Effect of radix actinidiae chinensis on human glioma cells and its mechanism

Wei Chen, Qianxue Chen, Bao-Hui Liu, Zhen-Tao Guo, Daofeng Tian

DOI

2015

Downregulation of RND3/RhoE in glioblastoma patients promotes tumorigenesis through augmentation of notch transcriptional complex activity

Bao-Hui Liu, Xi Lin, Xiang-Sheng Yang, Hui-Min Dong, Xiaojing Yue, Kelsey C. Andrade, Zhen-Tao Guo, Ji'an Yang, Li-Quan Wu, Xiao-Nan Zhu, Shen-Qi Zhang, Daofeng Tian, Jun-Min Wang, Qiang Cai, Qi-Zuan Chen, Shan-Ping Mao, Qian-Xue Chen, Jiang Chang

Cancer Medicine

DOI

2015

Original Article Puerarin inhibits proliferation and induces apoptosis in human glioblastoma cell lines

Ji-An Yang, Ji-Qiang Li, L. Shao, Qian Yang, Bao-Hui Liu, Ting-Feng Wu, Peng Wu, W. Yi, Qianxue Chen

2014

LRIG1 Enhances Chemosensitivity by Modulating BCL-2 Expression and Receptor Tyrosine Kinase Signaling in Glioma Cells

Zhen-Tao Guo, Qianxue Chen, Bao-Hui Liu, Daofeng Tian, Shen-Qi Zhang, Ming-Chang Li

Yonsei medical journal

DOI

2014

Construction of plasmid of B lymphocytes/leukemia-2 and its expression and function in U251 cells

Yue Liu, Qianxue Chen, Daofeng Tian, Bao-Hui Liu, Li-Quan Wu

DOI

2014

LRIG1 Improves Chemosensitivity Through Inhibition of BCL-2 and MnSOD in Glioblastoma

Jianjun Ding, Bao-Hui Liu, Yi He, Xian-Hou Yuan, Daofeng Tian, Bao-Wei Ji, Long Wang, Li-Quan Wu, Hui-Min Dong, Jun-Min Wang, Xiao-Nan Zhu, Q. Cai, Shen-Qi Zhang, Qianxue Chen

Cell Biochemistry and Biophysics

DOI

2014

骨形态发生蛋白4/Smad通路在胶质瘤耐药细胞U251/TMZ耐药逆转中的作用

Li-Quan Wu, Zhen-Tao Guo, Bao-Hui Liu, Daofeng Tian, Ji-An Yang, Shen-Qi Zhang, Qianxue Chen

DOI

2013

Effect of RhoE on apoptosis of human glioma U251 cells and the mechanism

Qi-Zuan Chen, Zhen-Tao Guo, Bao-Hui Liu, Jun-Hua Yu, Shen-Qi Zhang, Xiao-Nan Zhu, Ji'an Yang, G. Deng, Daofeng Tian, Qian-Xue Chen

DOI

2013

Zhen-Tao Guo, Bao-Hui Liu, Jun-Hua Yu, Bao-Wei Ji, Zhen-Gang Ji, Li-Quan Wu, Daofeng Tian, Qianxue Chen

DOI

2012

Xiao-Nan Zhu, Qianxue Chen, Bao-Hui Liu, Bao-Wei Ji, Daofeng Tian, Li-Quan Wu

DOI

2012

Schisandrin B protects PC12 cells by decreasing the expression of amyloid precursor protein and vacuolar protein sorting 35

Mingmin Yan, Shan-Ping Mao, Hui-Min Dong, Bao-Hui Liu, Qian Zhang, Gao-Feng Pan, Z. Fu

Neural Regeneration Research

DOI

2012

Experimental study on the mechanism of immunotherapy in human brain malignant gliomas with dendritic cell vaccine targeting of cancer stem cell in vitro

Bao-Wei Ji, Qianxue Chen, Bao-Hui Liu, Li-Quan Wu, Daofeng Tian, Zhen-Tao Guo, Zhen-Gang Ji

DOI

2012

The relationship of bone morhogenetic proteins 4 and chemotherapy sensitivity in glioma

Bao-Hui Liu, Qianxue Chen, Zhen-Gang Ji, Zhen-Tao Guo, Bao-Wei Ji, Xiao-Nan Zhu, Hui-Min Dong, Li-Quan Wu, Daofeng Tian, Q. Cai

DOI

2011

树突细胞肿瘤疫苗对U251细胞的作用

Bao-Hui Liu, Heng-Jia Shen, Qianxue Chen, Bao-Wei Ji, Zhen-Tao Guo, Li-Quan Wu

DOI

2011

Effects of adriamycin and bone morhogenetic proteins 4 in human brain glioma cell line U251 and probable signal pathway

Bao-Hui Liu, Daofeng Tian, Li-Quan Wu, Jun-Min Wang, W. Yi, Bao-Wei Ji, Hui-Min Dong, Qianxue Chen

DOI

2011

Effect of histone deacetylase inhibitor,MS-275 on proliferation of brain glioma cells

Bao-Hui Liu

2011

Indution of apoptosis of U251 cells by blocking STAT3 signaling pathways with MS-275

Bao-Wei Ji, Qianxue Chen, Daofeng Tian, Li-Quan Wu, Bao-Hui Liu, Zhen-Tao Guo, Zhen-Gang Ji, Xiao-Nan Zhu

DOI

2011

LRIG1与MnSOD、bcl-2在人脑星形胶质细胞瘤组织芯片中的表达

Zhen-Gang Ji, Bao-Hui Liu, Bao-Wei Ji, Zhen-Tao Guo, Li-Quan Wu, Daofeng Tian, Qianxue Chen

DOI

2010

Role of bone morhogenetic proteins 4 in the human brain glioma cell line U251

Bao-Hui Liu, Qianxue Chen, Daofeng Tian, Li-Quan Wu, Hui-Min Dong, Shen-Qi Zhang

DOI

2010

Effect of Bone Morphogenetic Protein 4 in the Human Brain Glioma Cell Line U251

Bao-Hui Liu, Daofeng Tian, W. Yi, Li-Quan Wu, Q. Cai, Hui-Min Dong, Heng-Jia Shen, Bao-Wei Ji, Long Wang, Shen-Qi Zhang, Dong Ruan, Qianxue Chen

Cell Biochemistry and Biophysics

DOI

2010

Gene therapy of rat intracranial glioma by Mesenchymal Stem Cells (MSCs) transfected with the beta-interferon gene

Daofeng Tian, Qianxue Chen, Li-Quan Wu, Bao-Wei Ji, Shen-Qi Zhang, Bao-Hui Liu, Long Wang, Zhi-Biao Chen, Q. Cai

DOI

2009

Expression of bone morphogenetic protein 4 in Adriamycin-induced inhibition in U251 cells

Bao-Hui Liu, Qianxue Chen, W. Yi, Li-Quan Wu, Hui-Min Dong, Shen-Qi Zhang

DOI

2005

玉米蔗糖磷酸合成酶(SPS)基因的克隆及表达载体的构建

李莹，刘宝辉，张中男，程大友，鲁兆新

《生物信息学》

精选作品

期刊论文

大豆GmbHLH119和GmbHLH120基因生物信息学及表达模式分析

大豆顶芽和腋芽酵母双杂交cDNA文库构建及SOC1a互作蛋白筛选

Recurrent Glioblastoma with Turcot Syndrome.

Research progress on the functions of NUCLEAR FACTOR-Y family in legumes

A GmWRKY20–GmbZIP9 transcriptional module synergistically activates GmANKTM21 to confer drought tolerance in soybean

Pyramiding nn16 and rin1 alleles to balance plant height and node number at high latitudes

Research advances on SOC1 genes in crop plants: from molecular insights to trait improvement

Phytochrome B modulates high-temperature-induced flowering in soybean by promoting degradation of PSEUDO-RESPONSE REGULATOR 5 proteins

Preferential induction of the Dt2 gene in the absence of E1 function enhances semi-determinate stem growth in soybean

Stepwise selection of Tof11/12 and GmRVE1 facilitates soybean adaptation to high-latitude regions

大豆GmBRI1基因家族的鉴定及其对根瘤菌侵染的响应

矮秆基因在大豆育种中的研究进展

大豆TPS基因家族在盐胁迫下的表达变化及单倍型选择规律分析

SLC10A3 regulates ferroptosis of glioblastoma through the STAT3/GPX4 pathway

Self-assembled genistein nanoparticles suppress the epithelial-mesenchymal transition in glioblastoma by targeting MMP9

Inflammatory signaling attenuates spliceosome function and cognitive ability

BBX32a and BBX32b Regulate Flowering Time in Soybean Under Long‐Day Conditions

Toward a Green Revolution in soybean: The role of ultra‐high‐density planting

Phloem Development and Function in Plants: Implications for Flowering, Nitrogen Fixation, and Crop Yield

Domestication‐medicated erect growth confines soybean basal branching by upregulating GmBRC1a and GmBRC1b

Natural allelic variation in SW14 determines seed weight and quality in soybean

Subfunctionalization, neofunctionalization, and nonfunctionalization of the four soybean phytochrome A genes

Carbon–nitrogen bottlenecks: A perfect storm to face in soybean yield improvement

Strategies for Balancing Growth and Defence Against Biotic Stress in Legumes

Genome-Wide Identification and Comprehensive Analysis of Ubiquitin-Specific Protease Gene Family in Soybean (Glycine max)

Multifaceted roles of FD gene family in flowering, plant architecture, and adaptation

The clock component LHY1b negatively regulates alkaline stress by repressing AOX1-mediated oxidative responses in soybean

Dt1 interacts with HB40 to affect lateral root primordium development by regulating CDC48 in soybean

Molecular Regulatory Network of Soybean Responses to Abiotic Stress

The LUX–SWI3C module regulates photoperiod sensitivity in Arabidopsis thaliana

Evening complex component ELF3 interacts with LUX proteins to repress soybean root nodulation

Genome-Wide Analysis of AGC Genes Related to Salt Stress in Soybeans (Glycine max)

Erratum to “Development of PmCDA1-based high-efficiency cytidine base editors (ChyCBEs) incorporating a GmRad51 DNA-binding domain in soybean” [New Crops 1 (2024) 100001]

Identification and Expression Analysis of the Soybean Serine Acetyltransferase (SAT) Gene Family Under Salt Stress

生育期基因E1～E4不同突变组合对大豆纬度适应性的影响

Use of circulating tumor cells and microemboli to predict diagnosis and prognosis in diffuse glioma.

RND1 inhibits epithelial-mesenchymal transition and temozolomide resistance of glioblastoma via AKT/GSK3-β pathway

Single-cell multi-omics sequencing uncovers region-specific plasticity of glioblastoma for complementary therapeutic targeting

Brain-targeted ursolic acid nanoparticles for anti-ferroptosis therapy in subarachnoid hemorrhage

LEAFY1 and 2 are required for floral organ development in soybean

Effects of decapitation on yield-related traits of total node number per plant in soybean

Artificial selection of two antagonistic E3 ubiquitin ligases finetunes soybean photoperiod adaptation and grain yield

The Critical Roles of Phosphatidylethanolamine‐Binding Proteins in Legumes

Post-Flowering Photoperiod Sensitivity of Soybean in Pod-Setting Responses

COL3a simultaneously regulates flowering and branching to improve grain yield in soybean

AP1c and SOC1 Form a Regulatory Feedback Loop to Regulate Flowering Time in Soybean

Molecular Regulation of Shoot Architecture in Soybean

Subfunctionalisation and self-repression of duplicated E1 homologues finetunes soybean flowering and adaptation

Soybean hypocotyl elongation is regulated by a MYB33 ‐ SWEET11 /21‐ GA2ox8c module involving long‐distance sucrose transport

J-family genes redundantly regulate flowering time and increase yield in soybean

Correction: Current overview on the genetic basis of key genes involved in soybean domestication

A critical suppression feedback loop determines soybean photoperiod sensitivity

Significance of Raffinose Family Oligosaccharides (RFOs) metabolism in plants

RETINOBLASTOMA RELATED 1 switches mitosis to meiosis in rice

Dt1 inhibits SWEET-mediated sucrose transport to regulate photoperiod-dependent seed weight in soybean

Genome-wide identification and expression analysis of the WNK kinase gene family in soybean

Corrigendum to “GmTOC1b negatively regulates resistance to Soybean mosaic virus”. [Crop J. 11 (2023) 1762–1773]

大豆NIN和NLP基因生物信息学分析及敲除载体构建

Ursolic acid nanoparticles for glioblastoma therapy.

Self‐Assembled nanoparticles of natural bioactive molecules enhance the delivery and efficacy of paclitaxel in glioblastoma

BZW1 as an oncogene is associated with patient prognosis and the immune microenvironment in glioma.

Decoding key cell sub-populations and molecular alterations in glioblastoma at recurrence by single-cell analysis

Soybean reduced internode 1 determines internode length and improves grain yield at dense planting

Genome-wide association study and RNA-seq identifies GmWRI1-like transcription factor related to the seed weight in soybean

SoyMD: a platform combining multi-omics data with various tools for soybean research and breeding

UV-B irradiation-activated E3 ligase GmILPA1 modulates gibberellin catabolism to increase plant height in soybean

Mechanisms underlying key agronomic traits and implications for molecular breeding in soybean

Regulation of soybean stem growth habit: A ten-year progress report

4kSoyGVP provides a referenced variation map for genetic research in soybean

GmTOC1b negatively regulates resistance to Soybean mosaic virus

Development of PmCDA1-based high-efficiency cytidine base editors (ChyCBEs) incorporating a GmRad51 DNA-binding domain in soybean

Natural variation of MS2 confers male fertility and drives hybrid breeding in soybean

The AP2 / ERF transcription factor TOE4b regulates photoperiodic flowering and grain yield per plant in soybean

Origin, variation, and selection of natural alleles controlling flowering and adaptation in wild and cultivated soybean

Genome-Wide Identification and Characterization of the Soybean Snf2 Gene Family and Expression Response to Rhizobia

Two soybean homologues of TERMINAL FLOWER 1 control flowering time under long day conditions

Natural variation of FKF1 controls flowering and adaptation during soybean domestication and improvement

A novel soybean malectin-like receptor kinase-encoding gene, GmMLRK1, provides resistance to soybean mosaic virus