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2026

Decoding antibody response to MERS-CoV in wild dromedary camels

F. Idoudi, Ruoke Wang, L. Tian, Ziqing Yang, K. Chik, Peng Chen, R. Benabderrazek, L. Fu, Ruijie Tan, Sayda Dhaouadi, Z. Benlasfar, M. Somia, Qi Zhang, Xuan-Ling Shi, Jasper Fuk-Woo Chan, Kwok-Yung Yuen, Xinquan Wang, B. Bouhaouala-Zahar, Lin-Qi Zhang

Proceedings of the National Academy of Sciences of the United States of America

精选作品

期刊论文

Decoding antibody response to MERS-CoV in wild dromedary camels

Structures of clinical antibodies bound to IL-33 uncover two distinct epitopes underlying differential efficacy

On-virion structural dynamics reveal temperature- and receptor-coordinated activation of an alphacoronavirus spike

Structural basis for human DPP4 receptor recognition by MERS-like coronaviruses 2014-422 and GX2012

Identification and characterization of bone marrow plasma cells producing IFN-γ-neutralizing autoantibodies in adult-onset immunodeficiency

Decoding antibody response to MERS-CoV in wild dromedary camels

Generation and characterization of neutralizing antibodies against M1R and B6R proteins of monkeypox virus

IgG‐Bridging–Seeded Synergistic Aggregation of SARS‐CoV‐2 Spikes Underlies Potent Neutralization by a Low‐Affinity Antibody

Exploring distinct modes of inter-spike cross-linking for enhanced neutralization by SARS-CoV-2 antibodies

Super broad and protective nanobodies against Sarbecoviruses including SARS-CoV-1 and the divergent SARS-CoV-2 subvariant KP.3.1.1

Dissecting the intricacies of human antibody responses to SARS-CoV-1 and SARS-CoV-2 infection

Inactivated vaccine-elicited potent antibodies can broadly neutralize SARS-CoV-2 circulating variants

Infection with wild-type SARS-CoV-2 elicits broadly neutralizing and protective antibodies against omicron subvariants

SARS-CoV-2 hijacks neutralizing dimeric IgA for nasal infection and injury in Syrian hamsters 1

Development of neutralizing antibodies against SARS-CoV-2, using a high-throughput single-B-cell cloning method

Broadly neutralizing and protective nanobodies against SARS-CoV-2 Omicron subvariants BA.1, BA.2, and BA.4/5 and diverse sarbecoviruses

Structural insights into the binding of SARS-CoV-2, SARS-CoV, and hCoV-NL63 spike receptor-binding domain to horse ACE2

Structural insights into the SARS-CoV-2 Omicron RBD-ACE2 interaction

Loss of Spike N370 glycosylation as an important evolutionary event for the enhanced infectivity of SARS-CoV-2

Cross-species binding spectrum of ACE2 to SARS-CoV-2 RBD

Cryoelectron microscopy structures of a human neutralizing antibody bound to MERS-CoV spike glycoprotein

Preclinical characterization of amubarvimab and romlusevimab, a pair of non-competing neutralizing monoclonal antibody cocktail, against SARS-CoV-2

Structural basis of a two-antibody cocktail exhibiting highly potent and broadly neutralizing activities against SARS-CoV-2 variants including diverse Omicron sublineages

The spike glycoprotein of highly pathogenic human coronaviruses: structural insights for understanding infection, evolution and inhibition

Structural basis of the IL-1 receptor TIR domain-mediated IL-1 signaling

RBD trimer mRNA vaccine elicits broad and protective immune responses against SARS-CoV-2 variants

CEBIT screening for inhibitors of the interaction between SARS-CoV-2 spike and ACE2

Susceptibilities of Human ACE2 Genetic Variants in Coronavirus Infection.

蝙蝠中菊头ACE2蛋白和多个动物ACE2是蝙蝠病毒RaTG13和新冠病毒的功能受体（英文）

A potent and protective human neutralizing antibody targeting a novel vulnerable site of Epstein-Barr virus

Characterization and structural basis of a lethal mouse-adapted SARS-CoV-2

Potent and protective IGHV3-53/3-66 public antibodies and their shared escape mutant on the spike of SARS-CoV-2

Analysis of SARS-CoV-2 variant mutations reveals neutralization escape mechanisms and the ability to use ACE2 receptors from additional species

Interleukin-17D regulates group 3 innate lymphoid cell function through its receptor CD93

Structural basis for bivalent binding and inhibition of SARS-CoV-2 infection by human potent neutralizing antibodies

Functional and genetic analysis of viral receptor ACE2 orthologs reveals a broad potential host range of SARS-CoV-2

The Rhinolophus affinis bat ACE2 and multiple animal orthologs are functional receptors for bat coronavirus RaTG13 and SARS-CoV-2

Antibody neutralization of SARS-CoV-2 through ACE2 receptor mimicry

From Crystal Structures of RgIA4 in Complex with Ac-AChBP to Molecular Determinants of Its High Potency of α9α10 nAChR

A Potent and Protective Human Neutralizing Antibody Against SARS-CoV-2 Variants

Mutation Y453F in the spike protein of SARS-CoV-2 enhances interaction with the mink ACE2 receptor for host adaption

Structural basis of tetanus toxin neutralization by native human monoclonal antibodies

Comparative analysis reveals the species-specific genetic determinants of ACE2 required for SARS-CoV-2 entry

Reduced graphene oxide membrane as supporting film for high-resolution cryo-EM

Structural basis of severe acute respiratory syndrome coronavirus 2 infection

Cryo-EM structures of HKU2 and SADS-CoV spike glycoproteins provide insights into coronavirus evolution

Targeted inhibition of activated protein C by a non-active-site inhibitory antibody to treat hemophilia

Human neutralizing antibodies elicited by SARS-CoV-2 infection

Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor

High Selectivity of an α-Conotoxin LvIA Analogue for α3β2 Nicotinic Acetylcholine Receptors Is Mediated by β2 Functionally Important Residues

A shedding soluble form of interleukin-17 receptor D exacerbates collagen-induced arthritis through facilitating TNF-α-dependent receptor clustering

Structural definition of a neutralization epitope on the N-terminal domain of MERS-CoV spike glycoprotein

Functional Relevance of Interleukin-1 Receptor Inter-domain Flexibility for Cytokine Binding and Signaling

Structural and functional definition of a vulnerable site on the hemagglutinin of highly pathogenic avian influenza A virus H5N1

Antibodies and vaccines against Middle East respiratory syndrome coronavirus

Single intranasal immunization with chimpanzee adenovirus-based vaccine induces sustained and protective immunity against MERS-CoV infection

Author Correction: Cryo-EM structure of the exocyst complex

Complementary recognition of the receptor-binding site of highly pathogenic H5N1 influenza viruses by two human neutralizing antibodies

Structural and functional characterization of HIV-1 cell fusion inhibitor T20

Structural Insights into the Mechanisms of Action of Short-Peptide HIV-1 Fusion Inhibitors Targeting the Gp41 Pocket

Exceptional potency and structural basis of a T1249-derived lipopeptide fusion inhibitor against HIV-1, HIV-2, and simian immunodeficiency virus

Cryo-EM structure of the exocyst complex

Structural insights into the species preference of the influenza B virus NS1 protein in ISG15 binding

Structural Definition of a Unique Neutralization Epitope on the Receptor-Binding Domain of MERS-CoV Spike Glycoprotein

Ultrapotent Human Neutralizing Antibody Repertoires Against Middle East Respiratory Syndrome Coronavirus From a Recovered Patient

Enfuvirtide (T20)-Based Lipopeptide Is a Potent HIV-1 Cell Fusion Inhibitor: Implications for Viral Entry and Inhibition

Erratum to: The crystal structure of Ac-AChBP in complex with α-conotoxin LvIA reveals the mechanism of its selectivity towards different nAChR subtypes

The crystal structure of Ac-AChBP in complex with α-conotoxin LvIA reveals the mechanism of its selectivity towards different nAChR subtypes

Structural Insights on PHA Binding Protein PhaP from Aeromonas hydrophila

From crystal structure of α-conotoxin GIC in complex with Ac-AChBP to molecular determinants of its high selectivity for α3β2 nAChR

Conformational Sampling and Binding Site Assessment of Suppression of Tumorigenicity 2 Ectodomain

Cryo-electron microscopy structures of the SARS-CoV spike glycoprotein reveal a prerequisite conformational state for receptor binding

Structural basis for the neutralization of MERS-CoV by a human monoclonal antibody MERS-27

Comprehensive analysis of antibody recognition in convalescent humans from highly pathogenic avian influenza H5N1 infection

Structural basis for the specific recognition of IL‐18 by its alpha receptor

Potent Neutralization of MERS-CoV by Human Neutralizing Monoclonal Antibodies to the Viral Spike Glycoprotein

Structural basis for the recognition of RNA polymerase II C-terminal domain by CREPT and p15RS

Tumor Necrosis Factor Receptor 2 (TNFR2)·Interleukin-17 Receptor D (IL-17RD) Heteromerization Reveals a Novel Mechanism for NF-κB Activation