李冰｜青岛大学｜学者主页

2026

RBM protein family: Focusing on the occurrence, progression and treatment of cancer

Huhu Zhang, Wenxin Zheng, Lingxi Li, Chenhui Geng, Yuxiang Wang, Jianyu Zhang, 孙玉兰, Xuanyu Zhang, Bing Li

Medical Oncology

DOI

2025

Immune modulation: the key to combat SARS-CoV-2 induced myocardial injury

Zhaoqing Li, Luning Qin, Xiaojian Xu, Ruolan Chen, Guoliang Zhang, Banghui Wang, Bing Li, Xian‐Ming Chu

Frontiers in Immunology

DOI

2025

The peptide from C- Phycocyanin alleviates myocardial ischemia-reperfusion injury by suppressing ferroptosis via upregulating UCHL3

Zhaoqing Li, Ruolan Chen, Luning Qin, Xiaojian Xu, Xuezhe Wang, Guoliang Zhang, Zhijun Liu, Banghui Wang, Bing Li, Xian‐Ming Chu

Free Radical Biology and Medicine

DOI

2025

Three Novel Mutations in TUBB8 Cause Female Infertility Due to Multiple Morphological Abnormalities of the Oocyte and Early Embryo

Duan Li, Guanghui Yuan, Xiaoxiao Wang, Jiao Zhuang, Lie Wang, Yingxue Liu, Xiaowen Liu, Linfang Han, Huaiqian Dou, Bing Li, Cuifang Hao

Reproductive Sciences

DOI

2024

METTL protein family: focusing on the occurrence, progression and treatment of cancer

Huhu Zhang, Fulin Sun, Shuyao Jiang, Fanghao Yang, Xiaolei Dong, Guoxiang Liu, Mengjun Wang, Ya Li, Mohan Su, Ziyuan Wen, Chunjuan Yu, Chenkai Fan, Xiaoxia Li, Zhe Zhang, Lina Yang, Bing Li

Biomarker Research

DOI

2024

MiR ‐10b‐5p alleviates Th2 inflammatory response by targeting SHP2 phosphatase in allergic rhinitis

Yumei Li, Xiangkun Zhao, Zhen Liu, Congxian Lu, Yaqi Wang, Jiahui Liu, Yakui Mou, Yu Zhang, Bing Li, Xicheng Song

Allergy

DOI

2024

USP32 facilitates non-small cell lung cancer progression via deubiquitinating BAG3 and activating RAF-MEK-ERK signaling pathway

Shuang Li, Lina Yang, Xiaoyan Ding, Hongxiao Sun, Xiaolei Dong, Fanghao Yang, Mengjun Wang, Huhu Zhang, Ya Li, Bing Li, Chunyan Liu

Oncogenesis

DOI

2024

RGS20 promotes non-small cell lung carcinoma proliferation via autophagy activation and inhibition of the PKA-Hippo signaling pathway

Xiaoyan Ding, Xiaoxia Li, Yanxia Jiang, Yujun Li, Hong Li, Lipeng Shang, Guilin Feng, Huhu Zhang, Ziyuan Xu, Lina Yang, Bing Li, Robert Chunhua Zhao

Cancer Cell International

DOI

2023

STAT3 as a therapeutic target in the metformin-related treatment

Weiran Zhang, Daisong Li, Bing Li, Xian‐Ming Chu, Bin Kong

International Immunopharmacology

DOI

2023

Bufalin targeting CAMKK2 inhibits the occurrence and development of intrahepatic cholangiocarcinoma through Wnt/β-catenin signal pathway

Huhu Zhang, Xiaolei Dong, Xiaoyan Ding, Guoxiang Liu, Fanghao Yang, Qinghang Song, Hongxiao Sun, Guang Chen, Shuang Li, Ya Li, Mengjun Wang, Tingting Guo, Zhe Zhang, Bing Li, Lina Yang

Journal of Translational Medicine

DOI

2023

Bufalin targeting BFAR inhibits the occurrence and metastasis of gastric cancer through PI3K/AKT/mTOR signal pathway

Guang Chen, Huhu Zhang, Hongxiao Sun, Xiaoyan Ding, Guoxiang Liu, Fanghao Yang, Guilin Feng, Xiaolei Dong, Yunfan Zhu, Xiaotong Wang, Yafei Wang, Bing Li, Lina Yang

APOPTOSIS

DOI

2023

P2X7 receptor of microglia in olfactory bulb mediates the pathogenesis of olfactory dysfunction in a mouse model of allergic rhinitis

Chao Ren, Yakui Mou, Xiao‐Yu Song, Xiao‐Yu Song, Shizhuang Wei, Hanrui Wang, Yao Wang, Wen‐Bin Zhang, Bing Li, Xicheng Song, Xicheng Song

The FASEB Journal

DOI

2023

Chitosan oligosaccharides attenuate programmed necrosis induced by oxidative stress in spermatogonia cells

Sudan Zhang, Xiaolei Dong, Jiane Liu, Chaozhong Yang, Baoqin Han, Bing Li, Zheng Wang

CyTA - Journal of Food

DOI

2023

Annexin A protein family: Focusing on the occurrence, progression and treatment of cancer

Huhu Zhang, Zhe Zhang, Tingting Guo, Guang Chen, Guoxiang Liu, Qinghang Song, Guichun Li, Fenghua Xu, Xiaolei Dong, Fanghao Yang, Can Cao, Di Zhong, Shuang Li, Ya Li, Mengjun Wang, Bing Li, Lina Yang

Frontiers in Cell and Developmental Biology

DOI

2023

The molecular mechanism of three novel peptides from C-phycocyanin alleviates MPTP-induced Parkinson's disease-like pathology in zebrafish

Fenghua Xu, Yuezi Qiu, Yun Zhang, Fanghao Yang, Min-min Ji, Kechun Liu, Meng Jin, Shanshan Zhang, Bing Li

Food & Function

DOI

2022

Three novel antioxidant peptides isolated from C-phycocyanin against H2O2-induced oxidative stress in zebrafish via Nrf2 signaling pathway

Fenghua Xu, Yun Liang Zhang, Yuezi Qiu, Fanghao Yang, Guoxiang Liu, Xiaolei Dong, Guang Chen, Can Cao, Qian Zhang, Shanshan Zhang, Bing Li

Frontiers in Marine Science

DOI

2022

Spatial separation of phosphatase and kinase activity within the Bub complex is required for proper mitosis

Lei Wang, Thomas Kruse, Blanca Lopez Mendez, Yuqing Zhang, Chunlin Song, Lei Zhu, Bing Li, Jing Fang, Zhimin Lü, Jakob Nilsson, Gang Zhang

Journal of Molecular Cell Biology

DOI

2022

Research progress in protein microarrays: Focussing on cancer research

Guang Chen, Lina Yang, Guoxiang Liu, Yunfan Zhu, Fanghao Yang, Xiaolei Dong, Fenghua Xu, Feng Zhu, Can Cao, Di Zhong, Shuang Li, Huhu Zhang, Bing Li

PROTEOMICS - CLINICAL APPLICATIONS

DOI

2022

Protective effect of C‐phycocyanin and apo‐phycocyanin subunit on programmed necrosis of GC ‐1 spg cells induced by H2O2

Xiaolei Dong, Fanghao Yang, Xiaohui Xu, Feng Zhu, Guoxiang Liu, Fenghua Xu, Guang Chen, Can Cao, Lei Teng, Xiaoxia Li, Lin Wang, Bing Li

Environmental Toxicology

DOI

2022

The protective effect of C-phycocyanin in male mouse reproductive system

Fanghao Yang, Xiaolei Dong, Guoxiang Liu, Lei Teng, Lin Wang, Feng Zhu, Fenghua Xu, Yifan Yang, Can Cao, Guang Chen, Bing Li

Food & Function

DOI

2021

A Review on Drug Delivery System for Tumor Therapy

Guoxiang Liu, Lina Yang, Guang Chen, Fenghua Xu, Fanghao Yang, Huaxin Yu, Lingne Li, Xiaolei Dong, Jingjing Han, Can Cao, Jingyu Qi, Junzhe Su, Xiaohui Xu, Xiaoxia Li, Bing Li

Frontiers in Pharmacology

DOI

2021

The Molecular Mechanisms of Cardiotoxicity Induced by HER2, VEGF, and Tyrosine Kinase Inhibitors: an Updated Review

Qinchao Wu, Baochen Bai, Chao Tian, Daisong Li, Haichu Yu, Bingxue Song, Bing Li, Xian‐Ming Chu

Cardiovascular Drugs and Therapy

DOI

2020

Targeted Antitumor Mechanism of C-PC/CMC-CD55sp Nanospheres in HeLa Cervical Cancer Cells

Guoxiang Liu, Xiaohui Xu, Liangqian Jiang, Huanhuan Ji, Feng Zhu, Bingnan Jin, Jingjing Han, Xiaolei Dong, Fanghao Yang, Bing Li

Frontiers in Pharmacology

DOI

2018

C-Phycocyanin exerts anti-cancer effects via the MAPK signaling pathway in MDA-MB-231 cells

Liangqian Jiang, Yujuan Wang, Guoxiang Liu, Huihui Liu, Feng Zhu, Huanhuan Ji, Bing Li

Cancer Cell International

DOI

2018

Molecular Mechanism of Anti-Cancer Activity of the Nano-Drug C-PC/CMC-CD59sp NPs in Cervical Cancer

Liangqian Jiang, Yujuan Wang, Feng Zhu, Guoxiang Liu, Huihui Liu, Huanhuan Ji, Shuhua Zheng, Bing Li

Journal of Cancer

DOI

2017

Phycocyanin: A Potential Drug for Cancer Treatment

Liangqian Jiang, Yujuan Wang, Qi-Feng Yin, Guoxiang Liu, Huihui Liu, Yajing Huang, Bing Li

Journal of Cancer

DOI

2017

The Targeted Antitumor Effects of C- PC/CMC-CD59sp Nanoparticles on HeLa Cells in Vitro and in Vivo

Yujuan Wang, Liangqian Jiang, Qi-Feng Yin, Huihui Liu, Guoxiang Liu, Guoteng Zhu, Bing Li

Journal of Cancer

DOI

2015

Study of the synergistic effects of all-transretinoic acid and C-phycocyanin on the growth and apoptosis of A549 cells

Bing Li, Meihua Gao, Cong-Yi Lv, Peng Yang, Qi-Feng Yin

European Journal of Cancer Prevention

DOI

2014

藻蓝蛋白联合全反式维甲酸诱导HeLa细胞凋亡的分子机制研究

李冰，杨帆，吕丛仪，杨鹏

《中国海洋药物》

2014

Molecular mechanism of inhibitory effects of C-phycocyanin combined with all-trans-retinoic acid on the growth of HeLa cells in vitro

Fan Yang, Bing Li, Xian‐Ming Chu, Cong-Yi Lv, Yingjie Xu, Peng Yang

Tumor Biology

DOI

2012

Identification of a novel short peptide seal specific to CD59 and its effect on HeLa cell growth and apoptosis

Bing Li, Meihua Gao, Xian‐Ming Chu, Yingjie Xu, Fan Yang

Cellular Oncology

DOI

李冰

精选作品

期刊论文

RBM protein family: Focusing on the occurrence, progression and treatment of cancer

Immune modulation: the key to combat SARS-CoV-2 induced myocardial injury

The peptide from C- Phycocyanin alleviates myocardial ischemia-reperfusion injury by suppressing ferroptosis via upregulating UCHL3

Three Novel Mutations in TUBB8 Cause Female Infertility Due to Multiple Morphological Abnormalities of the Oocyte and Early Embryo

METTL protein family: focusing on the occurrence, progression and treatment of cancer

MiR ‐10b‐5p alleviates Th2 inflammatory response by targeting SHP2 phosphatase in allergic rhinitis

USP32 facilitates non-small cell lung cancer progression via deubiquitinating BAG3 and activating RAF-MEK-ERK signaling pathway

RGS20 promotes non-small cell lung carcinoma proliferation via autophagy activation and inhibition of the PKA-Hippo signaling pathway

STAT3 as a therapeutic target in the metformin-related treatment

Bufalin targeting CAMKK2 inhibits the occurrence and development of intrahepatic cholangiocarcinoma through Wnt/β-catenin signal pathway

Bufalin targeting BFAR inhibits the occurrence and metastasis of gastric cancer through PI3K/AKT/mTOR signal pathway

P2X7 receptor of microglia in olfactory bulb mediates the pathogenesis of olfactory dysfunction in a mouse model of allergic rhinitis

Chitosan oligosaccharides attenuate programmed necrosis induced by oxidative stress in spermatogonia cells

Annexin A protein family: Focusing on the occurrence, progression and treatment of cancer

The molecular mechanism of three novel peptides from C-phycocyanin alleviates MPTP-induced Parkinson's disease-like pathology in zebrafish

Three novel antioxidant peptides isolated from C-phycocyanin against H2O2-induced oxidative stress in zebrafish via Nrf2 signaling pathway

Spatial separation of phosphatase and kinase activity within the Bub complex is required for proper mitosis

Research progress in protein microarrays: Focussing on cancer research

Protective effect of C‐phycocyanin and apo‐phycocyanin subunit on programmed necrosis of GC ‐1 spg cells induced by H2O2

The protective effect of C-phycocyanin in male mouse reproductive system

A Review on Drug Delivery System for Tumor Therapy

The Molecular Mechanisms of Cardiotoxicity Induced by HER2, VEGF, and Tyrosine Kinase Inhibitors: an Updated Review

Targeted Antitumor Mechanism of C-PC/CMC-CD55sp Nanospheres in HeLa Cervical Cancer Cells

C-Phycocyanin exerts anti-cancer effects via the MAPK signaling pathway in MDA-MB-231 cells

Molecular Mechanism of Anti-Cancer Activity of the Nano-Drug C-PC/CMC-CD59sp NPs in Cervical Cancer

Phycocyanin: A Potential Drug for Cancer Treatment

The Targeted Antitumor Effects of C- PC/CMC-CD59sp Nanoparticles on HeLa Cells in Vitro and in Vivo

Study of the synergistic effects of all-transretinoic acid and C-phycocyanin on the growth and apoptosis of A549 cells

藻蓝蛋白联合全反式维甲酸诱导HeLa细胞凋亡的分子机制研究

Molecular mechanism of inhibitory effects of C-phycocyanin combined with all-trans-retinoic acid on the growth of HeLa cells in vitro

Identification of a novel short peptide seal specific to CD59 and its effect on HeLa cell growth and apoptosis

预印本

S-adenosyl-L-methionine alleviates the senescence of ADSCs through the PI3K/AKT/FOXO3a signaling pathway

研究方向