百晓学者学者目录

徐萌

助理教授、博士生导师、教授，清华大学

精选作品

期刊论文

2025

Retraction: Methylation-mediated repression of microRNA-129-2 suppresses cell aggressiveness by inhibiting high mobility group box 1 in human hepatocellular carcinoma

Zhi-Kui Liu, Chang-Wei Dou, B. Yao, Meng Xu, Ling-Long Ding, Yu-Feng Wang, Yu-Li Jia, Qing Li, Hong-Yong Zhang, K. Tu, Tao Song, Qing-Guang Liu

OncoTarget

DOI

2025

Retraction: Ftx non coding RNA-derived miR-545 promotes cell proliferation by targeting RIG-I in hepatocellular carcinoma

Zhi-Kui Liu, Chang-Wei Dou, B. Yao, Meng Xu, Ling-Long Ding, Yu-Feng Wang, Yu-Li Jia, Qing Li, Hong-Yong Zhang, K. Tu, Tao Song, Qing-Guang Liu

OncoTarget

DOI

2022

BCL-3 promotes the tumor growth of hepatocellular carcinoma by regulating cell proliferation and the cell cycle through cyclin D1

K. Tu, Zhi-Kui Liu, B. Yao, Yu-Mo Xue, Meng Xu, Chang-Wei Dou, Guozhi Yin, Jun Wang

Oncology Report

DOI

2021

A role for intestinal alkaline phosphatase in preventing liver fibrosis

Yang Liu, P. Cavallaro, Byeong-Moo Kim, Tao Liu, Hong-Yan Wang, F. Kühn, Fatemeh Adiliaghdam, Enyu Liu, Robin Vasan, Ehsan Samarbafzadeh, Matthew Z. Farber, Junhui Li, Meng Xu, Vidisha Mohad, M. Choi, R. Hodin

Theranostics

DOI

2021

Focal Adhesion Kinase (FAK) promotes cholangiocarcinoma development and progression via YAP activation

Xinhua Song, Hong-Wei Xu, Pan Wang, Jing-Xiao Wang, S. Affò, Haichuan Wang, Meng Xu, Bin-yong Liang, L. Che, W. Qiu, R. Schwabe, Tammy T. Chang, Marion Vogl, G. Pes, S. Ribback, M. Evert, Xin Chen, D. Calvisi

Journal of Hepatology

DOI

2021

Distinct functions of transforming growth factor-β signaling in c-MYC driven hepatocellular carcinoma initiation and progression

Haichuan Wang, Pan Wang, Meng Xu, Xinhua Song, Hong Wu, M. Evert, D. Calvisi, Yong Zeng, Xin Chen

Cell Death and Disease

DOI

2021

Efficacy and Treatment Strategies in Advanced Cancers with Liver Metastasis Receiving Atezolizumab Therapy

wen-Jing Yin, Si-Cong Ma, Zhong-Yi Dong, Meng Xu, Wu Mao

Cancer Management and Research

DOI

2020

mTORC2 Signaling is Required for Liver Regeneration in a Cholestatic Liver Injury Murine Model.

Yi Zhou, Meng Xu, Pin Liu, Bin-yong Liang, Manning Qian, Haichuan Wang, Xinhua Song, Pranavanand Nyshadham, L. Che, D. Calvisi, Feng Li, Shu-Mei Lin, Xin Chen

American Journal of Pathology

DOI

2020

Single nucleotide polymorphisms in telomere length-related genes are associated with hepatocellular carcinoma risk in the Chinese Han population

Peng Huang, Rong Li, L. Shen, Weizhou He, Shuo Chen, Yu Dong, Jian-Cang Ma, Xi Chen, Meng Xu

Therapeutic Advances in Medical Oncology

DOI

2020

Cabozantinib-based combination therapy for the treatment of hepatocellular carcinoma

R. Shang, Xinhua Song, Pan Wang, Yi Zhou, Xin-Jun Lu, Jing-Xiao Wang, Meng Xu, Xin-Yan Chen, K. Utpatel, L. Che, Bin-yong Liang, A. Cigliano, M. Evert, D. Calvisi, Xin Chen

Gut

DOI

2020

Hyperactivation of IL-6/STAT3 pathway leaded to the poor prognosis of post-TACE HCCs by HIF-1α/SNAI1 axis-induced epithelial to mesenchymal transition

X. Gai, Peng Zhou, Meng Xu, Zhi-Kui Liu, Xin Zheng, Qing-Guang Liu

Journal of Cancer

DOI

2019

MEK inhibition suppresses cholangiocarcinoma growth by restraining tumor cell proliferation and modulating tumor microenvironment

K. Utpatel, Pan Wang, Xinhua Song, R. Shang, Meng Xu, L. Che, J. Gordan, X. Hu, X. Chen, Matthias Evert, D. Calvisi

Zeitschrift für Gastroenterologie - German Journal of Gastroenterology

DOI

2019

MEK inhibition suppresses K-Ras wild-type cholangiocarcinoma in vitro and in vivo via inhibiting cell proliferation and modulating tumor microenvironment

Pan Wang, Xinhua Song, K. Utpatel, R. Shang, Yoon Mee Yang, Meng Xu, Jie Zhang, L. Che, J. Gordan, A. Cigliano, E. Seki, M. Evert, D. Calvisi, Xiao-Song Hu, Xin Chen

Cell Death and Disease

DOI

2019

The mTORC2-Akt1 Cascade Is Crucial for c-Myc to Promote Hepatocarcinogenesis in Mice and Humans

Zhong Xu, Meng Xu, Pin Liu, Shu Zhang, R. Shang, Y. Qiao, L. Che, S. Ribback, A. Cigliano, K. Evert, R. Pascale, F. Dombrowski, M. Evert, Xi Chen, D. Calvisi, Xin Chen

Hepatology

DOI

2019

Axis inhibition protein 1 (Axin1) Deletion–Induced Hepatocarcinogenesis Requires Intact β-Catenin but Not Notch Cascade in Mice

Y. Qiao, Jing-Xiao Wang, E. Karagoz, Bin-yong Liang, Xinhua Song, R. Shang, K. Evert, Meng Xu, L. Che, M. Evert, D. Calvisi, Junyan Tao, Bruce Wang, Satdarshan P. S. Monga, Xin Chen

Hepatology

DOI

2019

SNAI1 Promotes the Cholangiocellular Phenotype, but not Epithelial–Mesenchymal Transition, in a Murine Hepatocellular Carcinoma Model

Meng Xu, Jing-Xiao Wang, Zhong Xu, Rong Li, Pan Wang, R. Shang, A. Cigliano, S. Ribback, A. Solinas, G. Pes, K. Evert, Haichuan Wang, Xinhua Song, Shu Zhang, L. Che, R. Pascale, D. Calvisi, Qing-Guang Liu, Xin Chen

Cancer Research

DOI

2019

A novel preclinical model of cholangiocarcinoma based on human aberrant FBXW7 expression.

Jing-Xiao Wang, Haichuan Wang, Michele Peters, Ning Ding, S. Ribback, K. Utpatel, M. Evert, A. Cigliano, F. Dombrowski, Xinhua Song, A. Cossu, Meng Xu, L. Che, J. Gordan, D. Calvisi, Xin Chen

Journal of Clinical Oncology

DOI

2019

Combined Treatment with MEK and mTOR Inhibitors is Effective in In Vitro and In Vivo Models of Hepatocellular Carcinoma

Xian-Qiong Liu, Jun-Jie Hu, Xinhua Song, K. Utpatel, Yi Zhang, Pan Wang, Xin-Jun Lu, Jie Zhang, Meng Xu, Tao Su, L. Che, Jing-Xiao Wang, M. Evert, D. Calvisi, Xin Chen

Cancers

DOI

2019

Inhibiting glutamine-dependent mTORC1 activation ameliorates liver cancers driven by β-catenin mutations

Adeola O. Adebayo Michael, Sungjin Ko, Junyan Tao, A. Moghe, Hong Yang, Meng Xu, Jacquelyn O. Russell, T. Pradhan-Sundd, Silvia Liu, Sucha Singh, M. Poddar, Jayvir S Monga, Pin Liu, M. Oertel, S. Ranganathan, A. Singhi, S. Rebouissou, J. Zucman-Rossi, S. Ribback, D. Calvisi, Natalia Qvartskhava, B. Görg, D. Häussinger, Xin Chen, Satdarshan P. S. Monga

Cell Metabolism

DOI

2019

Loss of Axin1 induced hepatocarcinogenesis requires intact β-Catenin but not Notch cascade in mice

K. Evert, Y. Qiao, Jing-Xiao Wang, E. Karagoz, Xinhua Song, Meng Xu, L. Che, Junyan Tao, Bruce Wang, Satdarshan P. S. Monga, X. Chen, M. Evert, D. Calvisi

Zeitschrift für Gastroenterologie - German Journal of Gastroenterology

DOI

2018

Loss of Pten synergizes with c-Met to promote hepatocellular carcinoma development via mTORC2 pathway

Zhong Xu, Jun-Jie Hu, Hui Cao, M. G. Pilo, A. Cigliano, Zi-Xuan Shao, Meng Xu, S. Ribback, F. Dombrowski, D. Calvisi, Xin Chen

Experimental and Molecular Medicine

DOI

2018

Hypoxia-induced up-regulation of VASP promotes invasiveness and metastasis of hepatocellular carcinoma

Zhi-Kui Liu, Yu-Feng Wang, Chang-Wei Dou, Meng Xu, Lian-Kang Sun, Liang Wang, B. Yao, Qing Li, Wei Yang, K. Tu, Qing-Guang Liu

Theranostics

DOI

2018

Oncogenic potential of N-terminal deletion and S45Y mutant β-catenin in promoting hepatocellular carcinoma development in mice

Y. Qiao, Meng Xu, Junyan Tao, L. Che, A. Cigliano, S. Monga, D. Calvisi, Xin Chen

BMC Cancer

DOI

2017

Long non-coding RNA CASC2 suppresses epithelial-mesenchymal transition of hepatocellular carcinoma cells through CASC2/miR-367/FBXW7 axis

Yu-Feng Wang, Zhi-Kui Liu, B. Yao, Qing Li, Liang Wang, Cong-Xia Wang, Chang-Wei Dou, Meng Xu, Qing-Guang Liu, K. Tu

Molecular Cancer

DOI

2017

EDG2 enhanced the progression of hepatocellular carcinoma by LPA/PI3K/AKT/ mTOR signaling

Meng Xu, Zhi-Kui Liu, Cong-Xia Wang, B. Yao, Xin Zheng

OncoTarget

DOI

2017

FSTL1 contributes to tumor progression via attenuating apoptosis in a AKT/GSK-3 β – dependent manner in hepatocellular carcinoma

Wei Yang, Yaqi Wu, Cong-Xia Wang, Zhi-Kui Liu, Meng Xu, Xin Zheng

Cancer Biomarkers

DOI

2016

(125)I-labeled anti-bFGF monoclonal antibody inhibits growth of hepatocellular carcinoma.

P. Hu, Lan-Hong Pan, Patrick Ting-Yat Wong, Wen-Hui Chen, Yan-Qing Yang, Hong Wang, Jun-Jian Xiang, Meng Xu

World Journal of Gastroenterology

DOI

2016

miR-141的过表达抑制MHCC-97H肝癌细胞的增殖和侵袭迁移

B. Yao, Yu-Mo Xue, Zhi-Kui Liu, Meng Xu, K. Tu, Jun Wang

2016

RIP1 upregulation promoted tumor progression by activating AKT/Bcl-2/BAX signaling and predicted poor postsurgical prognosis in HCC

Cong-Xia Wang, B. Yao, Meng Xu, Xin Zheng

Tumor Biology

DOI

2016

[Over-expression of miR-141 inhibits the proliferation, invasion and migration of hepatocellular carcinoma MHCC-97H cells].

B. Yao, Yu-Mo Xue, Zhi-Kui Liu, Meng Xu, K. Tu, Jun Wang

Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology

2016

Clinical significance of microRNA-155 expression in hepatocellular carcinoma.

C. Guan, Feng-Chun Yang, Xi-Chun He, Tu-Hua Li, Qingmei Yang, Hui-Ping He, Meng Xu

Oncology Letters

DOI

2016

BCAT1 promotes tumor cell migration and invasion in hepatocellular carcinoma

Meng Xu, Qing-Quan Liu, Yu-Li Jia, K. Tu, Ying-Min Yao, Qing-Guang Liu, Cheng Guo

Oncology Letters

DOI

2016

Lymphocyte‐specific protein 1 inhibits the growth of hepatocellular carcinoma by suppressing ERK1/2 phosphorylation

Hong-Yong Zhang, Yu-Feng Wang, Zhi-Kui Liu, B. Yao, Chang-Wei Dou, Meng Xu, Qing Li, Yu-Li Jia, Sheng-Li Wu, K. Tu, Qing-Guang Liu

FEBS Open Bio

DOI

2016

Chromatin assembly factor 1, subunit A (P150) facilitates cell proliferation in human hepatocellular carcinoma

Meng Xu, Yu-Li Jia, Zhi-Kui Liu, Ling-Long Ding, Run Tian, Hua Gu, Yu-Feng Wang, Hong-Yong Zhang, K. Tu, Qing-Guang Liu

OncoTargets and Therapy

DOI

2016

Methylation-mediated repression of microRNA-129-2 suppresses cell aggressiveness by inhibiting high mobility group box 1 in human hepatocellular carcinoma

Zhi-Kui Liu, Chang-Wei Dou, B. Yao, Meng Xu, Ling-Long Ding, Yu-Feng Wang, Yu-Li Jia, Qing Li, Hong-Yong Zhang, K. Tu, Tao Song, Qing-Guang Liu

OncoTarget

DOI

2016

PCAF inhibits hepatocellular carcinoma metastasis by inhibition of epithelial-mesenchymal transition by targeting Gli-1.

Qing Li, Zhi-Kui Liu, Meng Xu, Yu-Mo Xue, B. Yao, Chang-Wei Dou, Yu-Li Jia, Yu-Feng Wang, K. Tu, Xin Zheng, Ying-Min Yao

Cancer Letters

DOI

2016

Ftx non coding RNA-derived miR-545 promotes cell proliferation by targeting RIG-I in hepatocellular carcinoma

Zhi-Kui Liu, Chang-Wei Dou, B. Yao, Meng Xu, Ling-Long Ding, Yu-Feng Wang, Yu-Li Jia, Qing Li, Hong-Yong Zhang, K. Tu, Tao Song, Qing-Guang Liu

OncoTarget

DOI

2016

miR-187-3p inhibits the metastasis and epithelial-mesenchymal transition of hepatocellular carcinoma by targeting S100A4.

Chang-Wei Dou, Zhi-Kui Liu, Meng Xu, Yu-Li Jia, Yu-Feng Wang, Qing Li, Wei Yang, Xin Zheng, K. Tu, Qing-Guang Liu

Cancer Letters

DOI

2016

P300/CBP-associated factor (PCAF) inhibits the growth of hepatocellular carcinoma by promoting cell autophagy

Yu-Li Jia, Meng Xu, Chang-Wei Dou, Zhi-Kui Liu, Yu-Mo Xue, B. Yao, Ling-Long Ding, K. Tu, Xin Zheng, Qing-Guang Liu

Cell Death and Disease

DOI

2016

MIR-141の過剰発現は,MHCC-97H細胞の増殖と浸潤を阻害した。【JST・京大機械翻訳】

B. Yao, Yu-Mo Xue, Zhi-Kui Liu, Meng Xu, K. Tu, Jun Wang

2016

Long non-coding RNA TUSC7 acts a molecular sponge for miR-10a and suppresses EMT in hepatocellular carcinoma

Yu-Feng Wang, Zhi-Kui Liu, B. Yao, Chang-Wei Dou, Meng Xu, Yu-Mo Xue, Ling-Long Ding, Yu-Li Jia, Hong-Yong Zhang, Qing Li, K. Tu, Y. Jiao, Qing-Guang Liu, Cheng Guo

Tumor Biology

DOI

2016

肝細胞癌におけるNANOGの発現と意義【JST・京大機械翻訳】

Yu-Mo Xue, B. Yao, Zhi-Kui Liu, Meng Xu, K. Tu, Jun Wang

2016

IL-6/STAT3 axis initiated CAFs via up-regulating TIMP-1 which was attenuated by acetylation of STAT3 induced by PCAF in HCC microenvironment.

Xin Zheng, Meng Xu, B. Yao, Cong-Xia Wang, Yu-Li Jia, Qing-Guang Liu

Cellular Signalling

DOI

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