钱淑文｜复旦大学｜学者主页

2025

Obesity hinders the efficacy of adipose-derived stem cells for knee osteoarthritis by reducing the proportion of DPP4+ stem cells

Yan Tang, Zhenyu Xu, Saisai Song, Yan-Jue Song, Lijie Yang, Lei Wang, Yang Liu, Shuwen Qian, Zhiying Pang, Qi‐Qun Tang, Feng Yin

Stem Cells Translational Medicine

DOI

2024

A single-cell sequence analysis of mouse subcutaneous white adipose tissue reveals dynamic changes during weaning

Shuwen Qian, Chenyang Zhang, Yan Tang, Mengyuan Dai, Zhi‐Hui He, Hong Ma, Linyuan Wang, Qiqi Yang, Yang Liu, Wei Xu, Zhao Zhang, Qi‐Qun Tang

Communications Biology

DOI

2024

Artemisinins ameliorate polycystic ovarian syndrome by mediating LONP1-CYP11A1 interaction

Yang Liu, Jingjing Jiang, Shao-yue Du, Liangshan Mu, Jianjun Fan, Junchi Hu, Ye Yao, Meng Ding, Wei-yu Zhou, Qiuhan Yu, Yi-fan Xia, Hongyu Xu, Yi-jie Shi, Shuwen Qian, Yan Tang, Wei Li, Yongjun Dang, Xi Dong, Xiao-ying Li, Congjian Xu, Qi‐Qun Tang

Science

DOI

2024

NR2F6 is essential for brown adipocyte differentiation and systemic metabolic homeostasis

Weiyu Zhou, Pei‐Shan Liu, Yi-fan Xia, Yi-jie Shi, Hongyu Xu, Meng Ding, Qiqi Yang, Shuwen Qian, Yan Tang, Yan Lü, Qi‐Qun Tang, Yang Liu

Molecular Metabolism

DOI

2024

The secretory function of adipose tissues in metabolic regulation

Yang Liu, Shuwen Qian, Yan Tang, Qi‐Qun Tang

Life Metabolism

DOI

2023

CLCF1 signaling restrains thermogenesis and disrupts metabolic homeostasis by inhibiting mitochondrial biogenesis in brown adipocytes

Meng Ding, Hongyu Xu, Weiyu Zhou, Yi-fan Xia, Baiyu Li, Yi-jie Shi, Xin Dou, Qiqi Yang, Shuwen Qian, Yan Tang, Dongning Pan, Yang Liu, Qi‐Qun Tang

Proceedings of the National Academy of Sciences

DOI

2023

Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis

Yan Tang, Lijie Yang, Hao Liu, Yan-Jue Song, Qi-Qi Yang, Yang Liu, Shuwen Qian, Qi‐Qun Tang

Cell Reports

DOI

2022

Bone morphogenetic protein 4 in perivascular adipose tissue ameliorates hypertension through regulation of angiotensinogen

Wenjuan Mu, Yan-Jue Song, Lijie Yang, Shuwen Qian, Qiqi Yang, Yang Liu, Qi‐Qun Tang, Yan Tang

Frontiers in Cardiovascular Medicine

DOI

2022

GREM2 is associated with human central obesity and inhibits visceral preadipocyte browning

Wen Liu, Danjie Li, Minglan Yang, Long Wang, Yu Xu, Na Chen, Zhiyin Zhang, Juan Shi, Wen Li, Shaoqian Zhao, Aibo Gao, Yufei Chen, Qinyun Ma, Ruizhi Zheng, Shujing Wu, Yifei Zhang, Yuhong Chen, Shuwen Qian, Yufang Bi, Weiqiong Gu, Qi‐Qun Tang, Guang Ning, Ruixin Liu, Weiqing Wang, Jie Hong, Jiqiu Wang

EBioMedicine

DOI

2021

The protease SENP2 controls hepatic gluconeogenesis by regulating the SUMOylation of the fuel sensor AMPKα

Xin Dou, Weiyu Zhou, Meng Ding, Yin-jun Ma, Qiqi Yang, Shuwen Qian, Yan Tang, Qi‐Qun Tang, Yang Liu

Journal of Biological Chemistry

DOI

2021

Slit3 secreted from M2-like macrophages increases sympathetic activity and thermogenesis in adipose tissue

Yina Wang, Yan Tang, Zhi‐Hui He, Hong Ma, Linyuan Wang, Yang Liu, Qiqi Yang, Dongning Pan, Cuiqing Zhu, Shuwen Qian, Qi‐Qun Tang

Nature Metabolism

DOI

2021

Hepatic Small Ubiquitin‐Related Modifier (SUMO)–Specific Protease 2 Controls Systemic Metabolism Through SUMOylation‐Dependent Regulation of Liver–Adipose Tissue Crosstalk

Yang Liu, Xin Dou, Weiyu Zhou, Meng Ding, Ling Liu, Ruo‐qi Du, Liang Guo, Shuwen Qian, Yan Tang, Qi‐qi Yang, Dongning Pan, Xiao‐ying Li, Yan Lü, Jinke Cheng, Qi‐Qun Tang

Hepatology

DOI

2021

BMP4-mediated browning of perivascular adipose tissue governs an anti-inflammatory program and prevents atherosclerosis

Wenjuan Mu, Shuwen Qian, Yan-Jue Song, Lijie Yang, Saisai Song, Qiqi Yang, Hao Liu, Yang Liu, Dongning Pan, Yan Tang, Qi‐Qun Tang

Redox Biology

DOI

2021

Adipose tissue plasticity and the pleiotropic roles of BMP signaling

Shuwen Qian, Yan Tang, Qi‐Qun Tang

Journal of Biological Chemistry

DOI

2020

脂肪组织的神经调控概况

王艺娜，汤其群，钱淑文

《生命科学》

DOI

2020

SCD1 promotes lipid mobilization in subcutaneous white adipose tissue

Ying Zou, Yina Wang, Hong Ma, Zhi‐Hui He, Yan Tang, Liang Guo, Yang Liu, Meng Ding, Shuwen Qian, Qi‐Qun Tang

Journal of Lipid Research

DOI

2020

BMPR2 promotes fatty acid oxidation and protects white adipocytes from cell death in mice

Shuwen Qian, Jiabao Pan, Yan A. Su, Yan Tang, Yina Wang, Ying Zou, Yaxin Zhao, Hong Ma, Youyou Zhang, Yang Liu, Liang Guo, Qi‐Qun Tang

Communications Biology

DOI

2019

Stimulation of histamine H4 receptor participates in cold-induced browning of subcutaneous white adipose tissue

Yaxin Zhao, Jiabao Pan, Yina Wang, Ying Zou, Liang Guo, Qi‐Qun Tang, Shuwen Qian

American Journal of Physiology-Endocrinology and Metabolism

DOI

2018

RPS3A positively regulates the mitochondrial function of human periaortic adipose tissue and is associated with coronary artery diseases

Yan Tang, Yi He, Chen Li, Wenjuan Mu, Ying Zou, Conghui Liu, Shuwen Qian, Fuchuang Zhang, Jiabao Pan, Yina Wang, Haiyan Huang, Dongning Pan, Pengyuan Yang, Ju Mei, Rong Zeng, Qi‐Qun Tang

Cell Discovery

DOI

2018

Hepatocyte toll-like receptor 4 deficiency protects against alcohol-induced fatty liver disease

Lin Jia, Xiuli Chang, Shuwen Qian, Chen Liu, Caleb C. Lord, Newaz I. Ahmed, Charlotte E. Lee, Syann Lee, Laurent Gautron, Mack C. Mitchell, Jay D. Horton, Philipp E. Scherer, Joel Keith Elmquist

Molecular Metabolism

DOI

2018

BMP4 facilitates beige fat biogenesis via regulating adipose tissue macrophages

Shuwen Qian, Mengyuan Wu, Yina Wang, Yaxin Zhao, Ying Zou, Jiabao Pan, Yan Tang, Yang Liu, Liang Guo, Qi‐Qun Tang

Journal of Molecular Cell Biology

DOI

2017

Synthesis of cytochrome c oxidase 1 (SCO1) inhibits insulin sensitivity by decreasing copper levels in adipocytes

Xiangbo Wei, Liang Guo, Yang Liu, Shui-Rong Zhou, Yuan Liu, Xin Dou, Shao-yue Du, Meng Ding, Wan-Qiu Peng, Shuwen Qian, Haiyan Huang, Qi‐Qun Tang

Biochemical and Biophysical Research Communications

DOI

2017

The BMP4-Smad signaling pathway regulates hyperandrogenism development in a female mouse model

Yang Liu, Shao-yue Du, Meng Ding, Xin Dou, Feifei Zhang, Zhiyong Wu, Shuwen Qian, Wei Zhang, Qi‐Qun Tang, Congjian Xu

Journal of Biological Chemistry

DOI

2017

Acetylation of Cavin-1 Promotes Lipolysis in White Adipose Tissue

Shui-Rong Zhou, Liang Guo, Xu Wang, Yang Liu, Wan-Qiu Peng, Yuan Liu, Xiangbo Wei, Xin Dou, Meng Ding, Qun‐Ying Lei, Shuwen Qian, Xi Li, Qi‐Qun Tang

Molecular and Cellular Biology

DOI

2016

BMP4 mediates the interplay between adipogenesis and angiogenesis during expansion of subcutaneous white adipose tissue

Yan Tang, Shuwen Qian, Mengyuan Wu, Jue Wang, Ping Lü, Xi Li, Haiyan Huang, Liang Guo, Xia Sun, Congjian Xu, Qi‐Qun Tang

Journal of Molecular Cell Biology

DOI

2015

Large adipocytes function as antigen-presenting cells to activate CD4+ T cells via upregulating MHCII in obesity

Liuling Xiao, Xuguang Yang, Yuli Lin, S Li, Jingjing Jiang, Shuwen Qian, Qi‐Qun Tang, Rui He, Xiangwen Li

International Journal of Obesity

DOI

2015

Brown and beige fat: the metabolic function, induction, and therapeutic potential

Shuwen Qian, Haiyan Huang, Qi‐Qun Tang

Frontiers of Medicine

DOI

2013

诱导性产热脂肪的性质、诱导因素及潜在临床应用

黄海艳，钱淑文，汤其群

《中国细胞生物学学报》

2013

BMP4-mediated brown fat-like changes in white adipose tissue alter glucose and energy homeostasis

Shuwen Qian, Yan Tang, Xi Li, Yuan Liu, You-You Zhang, Hai-Yan Huang, Rui-Dan Xue, Hao-Yong Yu, Liang Guo, Hui-Di Gao, Yan Liu, Xia Sun, Yi-Ming Li, Weiping Jia, Qi-Qun Tang

Proceedings of the National Academy of Sciences

DOI

2009

人骨髓间充质干细胞分化为脂肪细胞过程中的基本特征及机制研究

钱淑文

《复旦大学》

钱淑文

精选作品

期刊论文

Obesity hinders the efficacy of adipose-derived stem cells for knee osteoarthritis by reducing the proportion of DPP4+ stem cells

A single-cell sequence analysis of mouse subcutaneous white adipose tissue reveals dynamic changes during weaning

Artemisinins ameliorate polycystic ovarian syndrome by mediating LONP1-CYP11A1 interaction

NR2F6 is essential for brown adipocyte differentiation and systemic metabolic homeostasis

The secretory function of adipose tissues in metabolic regulation

CLCF1 signaling restrains thermogenesis and disrupts metabolic homeostasis by inhibiting mitochondrial biogenesis in brown adipocytes

Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis

Bone morphogenetic protein 4 in perivascular adipose tissue ameliorates hypertension through regulation of angiotensinogen

GREM2 is associated with human central obesity and inhibits visceral preadipocyte browning

The protease SENP2 controls hepatic gluconeogenesis by regulating the SUMOylation of the fuel sensor AMPKα

Slit3 secreted from M2-like macrophages increases sympathetic activity and thermogenesis in adipose tissue

Hepatic Small Ubiquitin‐Related Modifier (SUMO)–Specific Protease 2 Controls Systemic Metabolism Through SUMOylation‐Dependent Regulation of Liver–Adipose Tissue Crosstalk

BMP4-mediated browning of perivascular adipose tissue governs an anti-inflammatory program and prevents atherosclerosis

Adipose tissue plasticity and the pleiotropic roles of BMP signaling

脂肪组织的神经调控概况

SCD1 promotes lipid mobilization in subcutaneous white adipose tissue

BMPR2 promotes fatty acid oxidation and protects white adipocytes from cell death in mice

Stimulation of histamine H4 receptor participates in cold-induced browning of subcutaneous white adipose tissue

RPS3A positively regulates the mitochondrial function of human periaortic adipose tissue and is associated with coronary artery diseases

Hepatocyte toll-like receptor 4 deficiency protects against alcohol-induced fatty liver disease

BMP4 facilitates beige fat biogenesis via regulating adipose tissue macrophages

Synthesis of cytochrome c oxidase 1 (SCO1) inhibits insulin sensitivity by decreasing copper levels in adipocytes

The BMP4-Smad signaling pathway regulates hyperandrogenism development in a female mouse model

Acetylation of Cavin-1 Promotes Lipolysis in White Adipose Tissue

BMP4 mediates the interplay between adipogenesis and angiogenesis during expansion of subcutaneous white adipose tissue

Large adipocytes function as antigen-presenting cells to activate CD4+ T cells via upregulating MHCII in obesity

Brown and beige fat: the metabolic function, induction, and therapeutic potential

诱导性产热脂肪的性质、诱导因素及潜在临床应用

BMP4-mediated brown fat-like changes in white adipose tissue alter glucose and energy homeostasis

人骨髓间充质干细胞分化为脂肪细胞过程中的基本特征及机制研究

会议论文

BMP4通过激活M2型巨噬细胞调控米色脂肪的生成

BMP4诱导白色脂肪棕色化并影响糖和能量代谢

预印本

BMPR2 Deficiency Inhibits Fatty Acid Oxidation and Renders White Adipocytes Vulnerable to TNFα-Induced Apoptosis

书籍章节

Lipids in the transcriptional regulation of adipocyte differentiation and metabolism