侯炜｜武汉大学｜学者主页

2026

血-组织屏障与病毒感染相互作用的研究进展

向淼，刘媛媛，侯炜

《巴楚医学》

2026

NPC1 promotes HTNV replication by controlling innate immune response

Hansong Qi, Yuechun Wu, Rong Wei, Shengyao Chen, Jumin Zhou, Wei Hou, Yang Xinglou

Frontiers in Immunology

DOI

2026

Persistent IFN-I signaling inhibits mitochondrial oxidative metabolism in CD8+ T cells during HIV-1 infection under cART

Liang Cheng, G. Li, Fei Luo, Wenwen Bi, Mengji Lu, Na Liu, Qiuchen Zhao, Runpeng Han, Hongyu Wang, Hao Yang, Jianping Ma, Wenjia Hu, Haisheng Yu, Wei Hou, Yong Xiong, Nilu P Goonetilleke, Richard Brad Jones, Lishan Su

Cellular and Molecular Immunology

DOI

2026

Metatranscriptomics reveals urbanization-driven divergence in rodent viromes and zoonotic risks in Chinese megacities

Zhou-Fu Xiang, Hui Wang, Fan Yang, S. Chen, Huang Ting-sheng, Si‐Qi Wang, Zi-hao Jiang, Yu Hu, Miao Xiang, Kexin Wang, Yu-zhu Wang, Yalan Huang, Yirong Li, Mǎng Shī, Wei Hou, Liangjun Chen

Communications Biology

DOI

2026

N6-methyladenosine modification of FZR1 mRNA positively regulates antiviral innate immunity by targeting the MAVS–TRAF3/6 axis

K. Dou, Yiyi Hu, Mingyang Li, Jiale Xu, Weihao Zhang, Hui Wang, Qi Cheng, Zihao Jiang, Liangjun Chen, Shi Liu, Ke Chen, Yuanyuan Liu, Hairong Xiong, Fan Luo, Wei Hou, Shuliang Chen

Proceedings of the National Academy of Sciences

DOI

2025

Phloroglucinol Oligomers from Callistemon rigidus as Novel Anti-Hantavirus Replication Agents

Jinxuan Yang, E-E Luo, Yue-Chun Wu, Kai Zhao, Wei Hou, Mu‐Yuan Yu, Xu‐Jie Qin, Xing‐Lou Yang

Viruses

DOI

2025

LncRNA MALAT1 Facilitates HIV-1 Replication by Upregulation of CHCHD2 and Downregulation of IFN-I Expression

Meirong Wang, Cheng-Si Bai, Jianwei Dai, Lan Yang, Fang-Yi Quan, Jie Ma, Xing-Yuan Chen, Shaowei Zhu, Yingqi Xu, Zhou-Fu Xiang, Ya-le Jiang, Qi Cheng, Weihao Zhang, Ke-han Chen, Jian‐Hua Wang, Yong Feng, Xiaoping Chen, Yong Xiong, Shuliang Chen, Wei Hou, Hairong Xiong

Molecular & Cellular Proteomics

DOI

2025

Hantaan virus glycoprotein Gc induces NEDD4‐dependent PTEN ubiquitination and degradation to escape the restriction of autophagosomes and facilitate viral propagation

Shuang Lu, Shuliang Chen, Yuqing Zhang, Xiaoli Mou, Mingyang Li, Shaowei Zhu, Xingyuan Chen, Tomas M. Strandin, Yale Jiang, Zhou-Fu Xiang, Yuanyuan Liu, Hairong Xiong, Deyin Guo, Liangjun Chen, Yirong Li, Wei Hou, Luo Fan

The FASEB Journal

DOI

2025

Aglycone Polyether Ionophores Affecting Actin Filaments as Broad-Spectrum Antiviral Agents

Minjian Huang, Jiaqi Li, Jing Li, Ben Hu, Ran Liu, Lianghao Huang, Caiqian Wang, Rong Hua, Chuanjian Wu, Zhu-Li Li, Zherui Zhang, Yanan Zhang, Yingjun Wu, Qiu-Yan Zhang, Yong Wang, Jing Liu, Zixin Deng, Wei Wang, Wei Hou, Ling Zhao, Yucheng Xia, Xiao‐Lian Zhang, Longfei Wang, Bo Zhang, Tiangang Liu

ACS Pharmacology & Translational Science

DOI

2024

MicroRNA let-7a regulation of Hantaan virus replication by Targeting FAS Signaling Pathways

Yuanyuan Liu, Ning Li, Xingyuan Chen, Hui Wang, Shaowei Zhu, Lan Yang, Fang-Yi Quan, Jian-Chun Ma, Jianwei Dai, Ya-le Jiang, Zhou-Fu Xiang, Qi Cheng, Weihao Zhang, Ke-Han Chen, Wei Hou, Hairong Xiong

Virology

DOI

2024

Discovery and genetic characterization of novel paramyxoviruses from small mammals in Hubei Province, Central China

Jia-le Xu, Jin-tao Chen, Bing Hu, Guo Wei-wei, Jingjing Guo, Chao-rui Xiong, Ling-xin Qin, Xin-nai Yu, Xiao-min Chen, Kun Cai, Yirong Li, Man‐Qing Liu, Liangjun Chen, Wei Hou

Microbial Genomics

DOI

2023

Pathogenicity of novel hantavirus isolate and antigenicity and immunogenicity of novel strain-based inactivated vaccine

Yuan-yuan Liu, Yingqi Xu, Yan Zhong, Fei Wei, Jiaxin Ling, Jinlin Li, Lan Yang, Fang-Yi Quan, Shuliang Chen, Fan Luo, Wei Hou, Zhanqiu Yang, Liangjun Chen, Hairong Xiong

Vaccine

DOI

2023

Direct blue 53, a biological dye, inhibits SARS-CoV-2 infection by blocking ACE2 and spike interaction in vitro and in vivo

Xiao Yu, Ling Wang, Shi-song Fang, Fan Luo, Shu-liang Chen, Lin Ye, Wei Hou

Virology

DOI

2023

Diversity and genetic characterization of orthohantavirus from small mammals and humans during 2012–2022 in Hubei Province, Central China

Jin-tao Chen, Jianbo Zhan, Ming-chao Zhu, Kaiji Li, Man‐Qing Liu, Bin Hu, Kun Cai, Hairong Xiong, Shuliang Chen, Weilong Tan, Liangjun Chen, Wei Hou

Acta Tropica

DOI

2023

Extensive genetic diversity of severe fever with thrombocytopenia syndrome virus circulating in Hubei Province, China, 2018–2022

Yu-ting Ren, Hongpan Tian, Jia-le Xu, Man‐Qing Liu, Kun Cai, Shuliang Chen, Xue-Bing Ni, Yirong Li, Wei Hou, Liangjun Chen

PLoS neglected tropical diseases

DOI

2023

Incidence of Orthohantavirus infection in humans follows observed changes in rodent reservoirs, Hubei Province, China (1984–2010)

Yuan-Yuan Liu, Yang An, Yingqi Xu, Yihui Zhang, Cheng-Si Bai, Yuqing Zhang, Xiao-Li Mou, Fan Luo, Shuliang Chen, Wei Hou, Zhanqiu Yang, Liangjun Chen, Hairong Xiong

American Journal of Veterinary Research

DOI

2022

Updates on CRISPR-based gene editing in HIV-1/AIDS therapy

Zhihao Zhang, Wei Hou, Shuliang Chen

Virologica Sinica

DOI

2022

Fentanyl enhances HIV infection in vitro

Jie Yan, Dong-hang Nie, Cheng-Si Bai, Abdul Rehman, An Yang, Xiao-Li Mou, Yuqing Zhang, Yingqi Xu, Qingqing Xiang, Yu-ting Ren, Jia-le Xu, Meirong Wang, Yong Feng, Xiaoping Chen, Yong Xiong, Hai-tao Hu, Hairong Xiong, Wei Hou

Virology

DOI

2021

TLR7 Activation of Macrophages by Imiquimod Inhibits HIV Infection through Modulation of Viral Entry Cellular Factors

Fengzhen Meng, Jinbiao Liu, Xu Wang, Peng Wang, Wenhui Hu, Wei Hou, Wen‐Zhe Ho

Biology

DOI

2021

Poly(dA:dT) Suppresses HSV-2 Infection of Human Cervical Epithelial Cells Through RIG-I Activation

Dandan Shao, Fengzhen Meng, Yu Liu, Xi-Qiu Xu, Xu Wang, Wenhui Hu, Wei Hou, Wen‐Zhe Ho

Frontiers in Immunology

DOI

2021

Type I Interferon Promotes Humoral Immunity in Viral Vector Vaccination

Chaojie Zhong, Feng‐Liang Liu, Renee L. Hajnik, Yao Lei, Kangjing Chen, Meirong Wang, Yuejin Liang, Jiaren Sun, Lynn Soong, Wei Hou, Haitao Hu

Journal of Virology

DOI

2021

Novel function of SART1 in HNF4α transcriptional regulation contributes to its antiviral role during HBV infection

Yan Teng, Zaichao Xu, Kaitao Zhao, Youquan Zhong, Jingjing Wang, Li Zhao, Zhixin Zheng, Wei Hou, Chengliang Zhu, Xinwen Chen, Ulrike Protzer, Yong Li, Yuchen Xia

Journal of Hepatology

DOI

2021

Epidemic Trend and Molecular Evolution of HV Family in the Main Hantavirus Epidemic Areas From 2004 to 2016, in P.R. China

Qiuwei Wang, Ming Yue, Pingping Yao, Changqiang Zhu, Lele Ai, Dan Hu, Bin Zhang, Zhangnv Yang, Xiaohong Yang, Fan Luo, Chunhui Wang, Wei Hou, Weilong Tan

Frontiers in Cellular and Infection Microbiology

DOI

2020

GTPase Activity of MxB Contributes to Its Nuclear Location, Interaction with Nucleoporins and Anti-HIV-1 Activity

Linlin Xie, Zhao Ju, Chaojie Zhong, Yingjun Wu, Yuxing Zan, Wei Hou, Yong Feng

Virologica Sinica

DOI

2020

Suppression of HIV-1 Integration by Targeting HIV-1 Integrase for Degradation with A Chimeric Ubiquitin Ligase

Zuopeng Zhang, Sen Yuan, Shuting Xu, Deyin Guo, Lang Chen, Wei Hou, Min Wang

Virologica Sinica

DOI

2020

Cathepsin L plays a key role in SARS-CoV-2 infection in humans and humanized mice and is a promising target for new drug development

Miao-Miao Zhao, Weili Yang, Fang-Yuan Yang, Li Zhang, Wei-Jing Huang, Wei Hou, Changfa Fan, R. Jin, Yingmei Feng, You-Chun Wang, Jin-Kui Yang

Signal Transduction and Targeted Therapy

DOI

2020

MxB impedes the NUP358-mediated HIV-1 pre-integration complex nuclear import and viral replication cooperatively with CPSF6

Linlin Xie, Lang Chen, Chaojie Zhong, Ting Yu, Zhao Ju, Meirong Wang, Hairong Xiong, Yan Zeng, Jian‐Hua Wang, Haitao Hu, Wei Hou, Yong Feng

Retrovirology

DOI

2020

HTNV Sensitizes Host Toward TRAIL-Mediated Apoptosis—A Pivotal Anti-hantaviral Role of TRAIL

Qing-Zhou Chen, Xin Wang, Fan Luo, Ning Li, Ni Zhu, Shuang Lu, Yu-xing Zan, Chao-Jie Zhong, Mei-Rong Wang, Hai-Tao Hu, Yǒng-Zhèn Zhāng, Hai-Rong Xiong, Wei Hou

Frontiers in Immunology

DOI

2020

Methadone Inhibits Viral Restriction Factors and Facilitates HIV Infection in Macrophages

Mei-Rong Wang, Di-Di Wu, Fan Luo, Chao-Jie Zhong, Xin Wang, Ni Zhu, Ying-Jun Wu, Hai-Tao Hu, Yong Feng, Xu Wang, Hai-Rong Xiong, Wei Hou

Frontiers in Immunology

DOI

2020

Diversity and circulation of Jingmen tick virus in ticks and mammals

Jingjing Guo, Xian‐Dan Lin, Yanmei Chen, Zong-yu Hao, Zhao-Xiao Wang, Zhu-Mei Yu, Miao Lu, Kun Li, Xin-Cheng Qin, Wen Wang, Edward Charles Holmes, Wei Hou, Yong‐Zhen Zhang

Virus Evolution

DOI

2020

Molecular Epidemiology and Vaccine Compatibility Analysis of Seasonal Influenza Viruses in Wuhan, 2016–2019

Liangjun Chen, Jingjing Guo, Weiwei Guo, E-Xiang Shen, Xin Wang, Kaiji Li, Jie Yan, Mǎng Shī, Yirong Li, Wei Hou

Virologica Sinica

DOI

2020

Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records

Huijun Chen, Juanjuan Guo, Chen Wang, Fan Luo, Xuechen B. Yu, Wei Zhang, Jiafu Li, Dongchi Zhao, Dan Xu, Qing Gong, Jing Liao, Huixia Yang, Wei Hou, Yuanzhen Zhang

The Lancet

DOI

2020

Genetic Variation on TNF/LTA and TNFRSF1A Genes is Associated with Outcomes of Hepatitis C Virus Infection

Ming Yue, Peng Huang, Chunhui Wang, Haozhi Fan, Ting Tian, Jingjing Wu, Fan Luo, Zuqiang Fu, Xueshan Xia, Ping Zhu, Jun Li, Yaping Han, Yun Zhang, Wei Hou

Immunological Investigations

DOI

2019

CCR5 editing by Staphylococcus aureus Cas9 in human primary CD4+ T cells and hematopoietic stem/progenitor cells promotes HIV-1 resistance and CD4+ T cell enrichment in humanized mice

Qiaoqiao Xiao, Shuliang Chen, Qiankun Wang, Zhepeng Liu, Shuai Liu, Huan Deng, Wei Hou, Dongcheng Wu, Yong Xiong, Jiafu Li, Deyin Guo

Retrovirology

DOI

2019

Correction to: CCR5 editing by Staphylococcus aureus Cas9 in human primary CD4+ T cells and hematopoietic stem/progenitor cells promotes HIV-1 resistance and CD4+ T cell enrichment in humanized mice

Qiaoqiao Xiao, Shuliang Chen, Qiankun Wang, Zhepeng Liu, Shuai Liu, Huan Deng, Wei Hou, Dongcheng Wu, Yong Xiong, Jiafu Li, Deyin Guo

Retrovirology

DOI

2019

Long noncoding RNA MALAT1 releases epigenetic silencing of HIV-1 replication by displacing the polycomb repressive complex 2 from binding to the LTR promoter

Di Qu, Weiwei Sun, Li Li, Li Ma, Li Xian Sun, Xia Jin, Taisheng Li, Wei Hou, Jian‐Hua Wang

Nucleic Acids Research

DOI

2019

Antiviral Properties of R. tanguticum Nanoparticles on Herpes Simplex Virus Type I In Vitro and In Vivo

Meng-xin Shen, Nian Ma, Minke Li, Yuan-yuan Liu, Tian Chen, Fei Wei, Dongying Liu, Wei Hou, Hairong Xiong, Yang Zhan-qiu

Frontiers in Pharmacology

DOI

2019

Assessment of a new arbidol derivative against herpes simplex virus II in human cervical epithelial cells and in BALB/c mice

Nian Ma, Meng-xin Shen, Tian Chen, Yuanyuan Liu, Yidong Mao, Liangjun Chen, Hairong Xiong, Wei Hou, Dongying Liu, Yang Zhan-qiu

Biomedicine & Pharmacotherapy

DOI

2019

Identification and characterization of a novel subtype of Tula virus in Microtus arvalis obscurus voles sampled from Xinjiang, China

Jintao Chen, Jing Qin, Kun Li, Qi-Yi Xu, Xiaoping Wang, Alexander Plyusnin, Wei Hou, Yǒng-Zhèn Zhāng

Infection Genetics and Evolution

DOI

2018

Bowman‒Birk Inhibitor Suppresses Herpes Simplex Virus Type 2 Infection of Human Cervical Epithelial Cells

Yu Liu, Xi-Qiu Xu, Biao Zhang, Jun Gu, Fengzhen Meng, Hang Liu, Li Zhou, Xu Wang, Wei Hou, Wen‐Zhe Ho

Viruses

DOI

2018

CRISPR/Cas9-mediated deletion of miR-146a enhances antiviral response in HIV-1 infected cells

Yan Teng, Mingqi Luo, Ting Yu, Lang Chen, Qiuling Huang, Shuliang Chen, Linlin Xie, Yan Zeng, Luo Fan, Hairong Xiong, Yuanyuan Liu, Wei Hou, Yong Feng

Genes and Immunity

DOI

2018

Distinct susceptibility of HIV vaccine vector-induced CD4 T cells to HIV infection

Sarah Auclair, Feng‐Liang Liu, Qingli Niu, Wei Hou, Gavin Churchyard, Cecilia A. Morgan, Nicole Frahm, Sorachai Nitayaphan, Punnee Pitisutthithum, Supachai Rerks‐Ngarm, Jason T. Kimata, Lynn Soong, Genoveffa Franchini, Merlin Lee Robb, Jérôme H. Kim, Nelson L. Michael, Haitao Hu

PLoS Pathogens

DOI

2018

HIV-1 inhibition in cells with CXCR4 mutant genome created by CRISPR-Cas9 and piggyBac recombinant technologies

Shuai Liu, Qiankun Wang, Xiao Yu, Yilin Li, Yandan Guo, Zhepeng Liu, Fuyun Sun, Wei Hou, Chunmei Li, Li Juan Wu, Deyin Guo, Shuliang Chen

Scientific Reports

DOI

2018

IFN-λs inhibit Hantaan virus infection through the JAK-STAT pathway and expression of Mx2 protein

Ning Li, Fan Luo, Qingzhou Chen, Ni Zhu, Hui Wang, Linlin Xie, Hairong Xiong, Ming Yue, Yun Zhang, Yong Feng, Wei Hou

Genes and Immunity

DOI

2018

Evaluation of Antibody-Dependent Enhancement of SARS-CoV Infection in Rhesus Macaques Immunized with an Inactivated SARS-CoV Vaccine

Fan Luo, Fan‐Lu Liao, Hui Wang, Hong-Bin Tang, Zhan-Qiu Yang, Wei Hou

Virologica Sinica

DOI

2017

Lack of association between integrin αvβ3 gene polymorphisms and hemorrhagic fever with renal syndrome in Han Chinese from Hubei, China

Xiaoping Chen, Hairong Xiong, Ni Zhu, Qingzhou Chen, Hui Wang, Chaojie Zhong, Meirong Wang, Shuang Lu, Fan Luo, Wei Hou

Virologica Sinica

DOI

2017

Molecular diagnosis of central nervous system opportunistic infections and mortality in HIV-infected adults in Central China

Rongrong Yang, Hong Zhang, Yong Xiong, Xien Gui, Yongxi Zhang, Liping Deng, Shicheng Gao, Mingqi Luo, Wei Hou, Deyin Guo

AIDS Research and Therapy

DOI

2017

Genome modification of CXCR4 by Staphylococcus aureus Cas9 renders cells resistance to HIV-1 infection

Qiankun Wang, Shuliang Chen, Qiaoqiao Xiao, Zhepeng Liu, Shuai Liu, Panpan Hou, Li Zhou, Wei Hou, Wen‐Zhe Ho, Chunmei Li, Li Juan Wu, Deyin Guo

Retrovirology

DOI

2017

Soybean-derived Bowman-Birk inhibitor (BBI) blocks HIV entry into macrophages

Tongcui Ma, Le Guo, Runhong Zhou, Xu Wang, Jin-Biao Liu, Jieliang Li, Yu Zhou, Wei Hou, Wen‐Zhe Ho

Virology

DOI

2017

Genome editing of the HIV co-receptors CCR5 and CXCR4 by CRISPR-Cas9 protects CD4+ T cells from HIV-1 infection

Zhepeng Liu, Shuliang Chen, Xu Jin, Qiankun Wang, Kongxiang Yang, Chenlin Li, Qiaoqiao Xiao, Panpan Hou, Shuai Liu, Shaoshuai Wu, Wei Hou, Yong Xiong, Chun‐Yan Kong, Xixian Zhao, Li Juan Wu, Chunmei Li, Guihong Sun, Deyin Guo

Cell & Bioscience

DOI

2017

Priming and Activation of Inflammasome by Canarypox Virus Vector ALVAC via the cGAS/IFI16–STING–Type I IFN Pathway and AIM2 Sensor

Feng‐Liang Liu, Qingli Niu, Xiuzhen Fan, Connie Liu, Jie Zhang, Zhi Wei, Wei Hou, Thirumala‐Devi Kanneganti, Merlin Lee Robb, Jérôme H. Kim, Nelson L. Michael, Jiaren Sun, Lynn Soong, Haitao Hu

The Journal of Immunology

DOI

2017

Antiviral activity of arbidol hydrochloride against herpes simplex virus I in vitro and in vivo

Minke Li, Yuan-yuan Liu, Fei Wei, Meng-xin Shen, Yan Zhong, Shan Li, Liangjun Chen, Nian Ma, Bingyu Liu, Yidong Mao, Ning Li, Wei Hou, Hairong Xiong, Yang Zhan-qiu

International Journal of Antimicrobial Agents

DOI

2017

HTNV-induced upregulation of miR-146a in HUVECs promotes viral infection by modulating pro-inflammatory cytokine release

Qingzhou Chen, Fan Luo, Ming-Xiang Lu, Ning Li, Yan Teng, Qiuling Huang, Ni Zhu, Guan-Yi Wang, Ming Yue, Yun Zhang, Yong Feng, Hairong Xiong, Wei Hou

Biochemical and Biophysical Research Communications

DOI

2017

Phylogenetic analysis based on mitochondrial DNA sequences of wild rats, and the relationship with Seoul virus infection in Hubei, China

Dongying Liu, Jing Liu, Bingyu Liu, Yuan-Yuan Liu, Hairong Xiong, Wei Hou, Zhanqiu Yang

Virologica Sinica

DOI

2016

Sequential Dysfunction and Progressive Depletion of Candida albicans-Specific CD4 T Cell Response in HIV-1 Infection

Feng‐Liang Liu, Xiuzhen Fan, Sarah Auclair, Monique R. Ferguson, Jiaren Sun, Lynn Soong, Wei Hou, Robert Redfield, Deborah L. Birx, Silvia Ratto‐Kim, Merlin Lee Robb, Jérôme H. Kim, Nelson L. Michael, Haitao Hu

PLoS Pathogens

DOI

2016

Soybean-derived Bowman-Birk Inhibitor (BBI) Inhibits HIV Replication in Macrophages

Tongcui Ma, Runhong Zhou, Xu Wang, Jieliang Li, Ming Sang, Li Zhou, Ke Zhuang, Wei Hou, Deyin Guo, Wen‐Zhe Ho

Scientific Reports

DOI

2016

pH-dependent conformational changes of a Thogoto virus matrix protein reveal mechanisms of viral assembly and uncoating

Mingrui Yang, Feng Feng, Yingfang Liu, Hui Wang, Zhanqiu Yang, Wei Hou, Huanhuan Liang

Journal of General Virology

DOI

2016

Specific interference shRNA-expressing plasmids inhibit Hantaan virus infection in vitro and in vivo

Yuan-yuan Liu, Liangjun Chen, Yan Zhong, Meng-xin Shen, Nian Ma, Bingyu Liu, Fan Luo, Wei Hou, Zhanqiu Yang, Hairong Xiong

Acta Pharmacologica Sinica

DOI

2015

PLGA-PEG Nanoparticles Coated with Anti-CD45RO and Loaded with HDAC Plus Protease Inhibitors Activate Latent HIV and Inhibit Viral Spread

Xiaolong Tang, Yong Liang, Xinkuang Liu, Shuping Zhou, Liang Liu, Fujina Zhang, Chunmei Xie, Shuyu Cai, Jia Wei, Yongqiang Zhu, Wei Hou

Nanoscale Research Letters

DOI

2015

Genome editing of CXCR4 by CRISPR/cas9 confers cells resistant to HIV-1 infection

Panpan Hou, Shuliang Chen, Shilei Wang, Xiao Yu, Yu Zheng Chen, Meng Jiang, Ke Zhuang, Wen‐Zhe Ho, Wei Hou, Jian Yuan Huang, Deyin Guo

Scientific Reports

DOI

2014

Influence of HLA-DRB alleles on haemorrhagic fever with renal syndrome in a Chinese Han population in Hubei Province, China

Ni Zhu, Fangyu Luo, Q. Chen, N. Li, Hairong Xiong, Yong Feng, Zhanqiu Yang, Wei Hou

European Journal of Clinical Microbiology & Infectious Diseases

DOI

2014

The Epidemic Characteristics and Changing Trend of Hemorrhagic Fever with Renal Syndrome in Hubei Province, China

Yihui Zhang, Liang Ge, Li Liu, Xixiang Huo, Hairong Xiong, Yuan-Yuan Liu, Dongying Liu, Fan Luo, Jinlin Li, Jiaxin Ling, Wen Chen, Jing Liu, Wei Hou, Yun Zhang, Hong Mei Fan, Zhanqiu Yang

PLoS ONE

DOI

2013

The association of HLA-DRB1 alleles and drug use with HIV infection in a Chinese Han Cohort

Bo Diao, Juan Du, Ying Liu, Luo Fan, Wei Hou

The Brazilian Journal of Infectious Diseases

DOI

2013

In Vitro and in Vivo Studies of the Inhibitory Effects of Emodin Isolated from Polygonum cuspidatum on Coxsakievirus B4

Zhao Liu, Fei Wei, Liang-Jun Chen, Hairong Xiong, Yuan Yuan Liu, Fan Luo, Wei Hou, Hong Xiao, Yang Zhan-qiu

Molecules

DOI

2013

Jiawei-Yupingfeng-Tang, a Chinese herbal formula, inhibits respiratory viral infections in vitro and in vivo

Qiang Liu, Li Lü, Moli Hua, Yu Fu Xu, Hairong Xiong, Wei Hou, Yang Zhan-qiu

Journal of Ethnopharmacology

DOI

2013

Antiviral and anti-inflammatory activity of arbidol hydrochloride in influenza A (H1N1) virus infection

Qiang Liu, Hairong Xiong, Li Lü, Yuan-Yuan Liu, Fan Luo, Wei Hou, Yang Zhan-qiu

Acta Pharmacologica Sinica

DOI

2012

CD56+ T cells inhibit HIV-1 infection of macrophages

Wei Hou, Li Ye, Wen‐Zhe Ho

Journal of Leukocyte Biology

DOI

2012

Establishment of SYBR green-based qPCR assay for rapid evaluation and quantification for anti-Hantaan virus compounds in vitro and in suckling mice

Fei Wei, Jinlin Li, Jiaxin Ling, Liangjun Chen, Ning Li, Yuan-Yuan Liu, Fan Luo, Hairong Xiong, Wei Hou, Yang Zhan-qiu

Virus Genes

DOI

2012

Amelioration of influenza virus-induced reactive oxygen species formation by epigallocatechin gallate derived from green tea

Jiaxin Ling, Fei Wei, Ning Li, Jinlin Li, Liangjun Chen, Yuan-yuan Liu, Fan Luo, Hairong Xiong, Wei Hou, Zhanqiu Yang

Acta Pharmacologica Sinica

DOI

2012

Genetic characterization of a new subtype of Hantaan virus isolated from a hemorrhagic fever with renal syndrome (HFRS) epidemic area in Hubei Province, China

Jinlin Li, Jiaxin Ling, Dongying Liu, Jing Liu, Yuan-yuan Liu, Fei Wei, Fan Luo, Wen Chen, Yihui Zhang, Hairong Xiong, Wei Hou, Zhanqiu Yang

Archives of Virology

DOI

2012

L-Ficolin Binds to the Glycoproteins Hemagglutinin and Neuraminidase and Inhibits Influenza A Virus Infection Both in vitro and in vivo

Qin Pan, Haidan Chen, Feng Wang, Victor Tunje Jeza, Wei Hou, Yinglan Zhao, Xiang Tian, Ying Zhu, Yuchi Endo, Teizo Fujita, Xiao‐Lian Zhang

Journal of Innate Immunity

DOI

2012

The Inhibitory Effect of Rheum palmatum Against Coxsackievirus B3in Vitro and in Vivo

Hairong Xiong, Shen Yuan-ying, Li Lü, Wei Hou, Fan Luo, Hong Xiao, Zhanqiu Yang

The American Journal of Chinese Medicine

DOI

2011

CTLA-4基因单倍型与吸毒合并HIV感染的相关性研究

刘莹，刁波，申元英，周芳，冯勇，罗凡，侯炜

《联勤军事医学》

2011

细胞毒T淋巴细胞相关抗原4基因多态性与吸毒并HIV感染相关

刘莹，刁波，申元英，周芳，冯勇，罗凡，侯炜

《基础医学与临床》

2011

吸毒合并HIV感染与HLA-DRB1*1301/1302等位基因的相关性

刁波，刘莹，申元英，周芳，冯勇，罗凡，侯炜

《联勤军事医学》

2011

HLA-DRB1基因多态性与吸毒合并HIV感染的相关性

刁波，刘莹，申元英，周芳，冯勇，罗凡，侯炜

《解放军预防医学杂志》

2011

Genetic analysis of hantaviruses and their rodent hosts in central-south China

Jing Liu, Dongying Liu, Wen Chen, Jinlin Li, Fan Luo, Qing Li, Jiaxin Ling, Yuan-Yuan Liu, Hairong Xiong, Xiaohua Ding, Wei Hou, Yun Zhang, Shiyue Li, Jie Wang, Zhanqiu Yang

Virus Research

DOI

2010

Toll样受体与HIV-1病毒感染

孙黎，侯炜

《武汉大学学报(医学版)》

2010

The effect of emodin, an anthraquinone derivative extracted from the roots of Rheum tanguticum, against herpes simplex virus in vitro and in vivo

Hairong Xiong, Jun Luo, Wei Hou, Hong Xiao, Yang Zhan-qiu

Journal of Ethnopharmacology

DOI

2009

L-ficolin对A型H1N1流感病毒感染小鼠的保护作用

潘勤，侯炜，Victor Tunje Jeza，章晓联

《武汉大学学报(医学版)》

2009

NKT细胞和HIV感染

黄孝军，侯炜

《武汉大学学报(医学版)》

2009

Toll样受体3抑制人类巨噬细胞感染HIV的机制研究

周玉，王旭，侯炜，胡权，刘满清，周敦金，霍文哲

《激光生物学报》

2009

An important role for type III interferon(IFN-lambda) in anti-HIV activity

Yinglan Zhao, Li Sun, Wei Hou

Zhonghua weishengwuxue he mianyixue zazhi

DOI

2009

Lambda Interferon Inhibits Human Immunodeficiency Virus Type 1 Infection of Macrophages

Wei Hou, Xu Wang, Li Ye, Lin Zhou, Zhanqiu Yang, Eric Riedel, Wen‐Zhe Ho

Journal of Virology

DOI

2007

Antiviral activity of arbidol against influenza A virus, respiratory syncytial virus, rhinovirus, coxsackie virus and adenovirus in vitro and in vivo

Lang Shi, Hairong Xiong, Jing He, H. Deng, Qijie Li, Q. Zhong, Wei Hou, L. Cheng, Hong Xiao, Z. Yang

Archives of Virology

DOI

2007

Intratracheal inoculation of severe acute respiratory syndrome coronavirus in monkeys Macaca rhesus.

Fangyu Luo, Wei Hou, Zhanqiu Yang, Zhidong Tang, Y Wang, Qingyun Xian, Lihua Sun

PubMed

2006

草血竭抗流感病毒的研究

罗凡，侯炜，杨占秋，郝建新，锡谷达夫，森修一

《武汉大学学报(医学版)》

2005

实验性SARS-CoV灭活疫苗对恒河猴的免疫原性与安全性研究

钟琼，杨占秋，周俊，王薇，侯炜，朱润庆，唐志娇，王勇，鲜巧阳

《中华微生物学和免疫学杂志》

2005

Immunogenicity, safety, and protective efficacy of an inactivated SARS-associated coronavirus vaccine in rhesus monkeys

Jun Zhou, Wei Wang, Qiong Zhong, Wei Hou, Zhanqiu Yang, Shu‐Yuan Xiao, Zhu Runqing, Zhijiao Tang, Yong Wang, Qiaoyang Xian, Hongbing Tang, Li Wen

Vaccine

DOI

2003

汉滩病毒M片段的核苷酸序列变异和系统发生树分析

丁晓华，杨占秋，肖红，陈晓湘，徐芳玲，侯炜，文利

《病毒学报》

2003

RT-PCR扩增汉滩病毒及其核苷酸序列的发生树分析

丁晓华，杨占秋，肖红，陈晓湘，徐芳玲，侯炜，文利

《中华微生物学和免疫学杂志》

2002

人巨细胞病毒感染与自然流产关系的研究

毛琳，李向群，侯炜，申元英，邓子琴，李宗山，杨占秋

《中国公共卫生》

2002

湖北省不同地区汉坦病毒的基因型研究

侯炜，杨占秋，杨继江，赵旻，刘汉燕，曲虹，刘东瀛，丁晓华

《中国公共卫生》

精选作品

期刊论文

血-组织屏障与病毒感染相互作用的研究进展

NPC1 promotes HTNV replication by controlling innate immune response

Persistent IFN-I signaling inhibits mitochondrial oxidative metabolism in CD8+ T cells during HIV-1 infection under cART

Metatranscriptomics reveals urbanization-driven divergence in rodent viromes and zoonotic risks in Chinese megacities

N6-methyladenosine modification of FZR1 mRNA positively regulates antiviral innate immunity by targeting the MAVS–TRAF3/6 axis

Phloroglucinol Oligomers from Callistemon rigidus as Novel Anti-Hantavirus Replication Agents

LncRNA MALAT1 Facilitates HIV-1 Replication by Upregulation of CHCHD2 and Downregulation of IFN-I Expression

Hantaan virus glycoprotein Gc induces NEDD4‐dependent PTEN ubiquitination and degradation to escape the restriction of autophagosomes and facilitate viral propagation

Aglycone Polyether Ionophores Affecting Actin Filaments as Broad-Spectrum Antiviral Agents

MicroRNA let-7a regulation of Hantaan virus replication by Targeting FAS Signaling Pathways

Discovery and genetic characterization of novel paramyxoviruses from small mammals in Hubei Province, Central China

Pathogenicity of novel hantavirus isolate and antigenicity and immunogenicity of novel strain-based inactivated vaccine

Direct blue 53, a biological dye, inhibits SARS-CoV-2 infection by blocking ACE2 and spike interaction in vitro and in vivo

Diversity and genetic characterization of orthohantavirus from small mammals and humans during 2012–2022 in Hubei Province, Central China

Extensive genetic diversity of severe fever with thrombocytopenia syndrome virus circulating in Hubei Province, China, 2018–2022

Incidence of Orthohantavirus infection in humans follows observed changes in rodent reservoirs, Hubei Province, China (1984–2010)

Updates on CRISPR-based gene editing in HIV-1/AIDS therapy

Fentanyl enhances HIV infection in vitro

TLR7 Activation of Macrophages by Imiquimod Inhibits HIV Infection through Modulation of Viral Entry Cellular Factors

Poly(dA:dT) Suppresses HSV-2 Infection of Human Cervical Epithelial Cells Through RIG-I Activation

Type I Interferon Promotes Humoral Immunity in Viral Vector Vaccination

Novel function of SART1 in HNF4α transcriptional regulation contributes to its antiviral role during HBV infection

Epidemic Trend and Molecular Evolution of HV Family in the Main Hantavirus Epidemic Areas From 2004 to 2016, in P.R. China

GTPase Activity of MxB Contributes to Its Nuclear Location, Interaction with Nucleoporins and Anti-HIV-1 Activity

Suppression of HIV-1 Integration by Targeting HIV-1 Integrase for Degradation with A Chimeric Ubiquitin Ligase

Cathepsin L plays a key role in SARS-CoV-2 infection in humans and humanized mice and is a promising target for new drug development

MxB impedes the NUP358-mediated HIV-1 pre-integration complex nuclear import and viral replication cooperatively with CPSF6

HTNV Sensitizes Host Toward TRAIL-Mediated Apoptosis—A Pivotal Anti-hantaviral Role of TRAIL

Methadone Inhibits Viral Restriction Factors and Facilitates HIV Infection in Macrophages

Diversity and circulation of Jingmen tick virus in ticks and mammals

Molecular Epidemiology and Vaccine Compatibility Analysis of Seasonal Influenza Viruses in Wuhan, 2016–2019

Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records

Genetic Variation on TNF/LTA and TNFRSF1A Genes is Associated with Outcomes of Hepatitis C Virus Infection

CCR5 editing by Staphylococcus aureus Cas9 in human primary CD4+ T cells and hematopoietic stem/progenitor cells promotes HIV-1 resistance and CD4+ T cell enrichment in humanized mice

Correction to: CCR5 editing by Staphylococcus aureus Cas9 in human primary CD4+ T cells and hematopoietic stem/progenitor cells promotes HIV-1 resistance and CD4+ T cell enrichment in humanized mice

Long noncoding RNA MALAT1 releases epigenetic silencing of HIV-1 replication by displacing the polycomb repressive complex 2 from binding to the LTR promoter

Antiviral Properties of R. tanguticum Nanoparticles on Herpes Simplex Virus Type I In Vitro and In Vivo

Assessment of a new arbidol derivative against herpes simplex virus II in human cervical epithelial cells and in BALB/c mice

Identification and characterization of a novel subtype of Tula virus in Microtus arvalis obscurus voles sampled from Xinjiang, China

Bowman‒Birk Inhibitor Suppresses Herpes Simplex Virus Type 2 Infection of Human Cervical Epithelial Cells

CRISPR/Cas9-mediated deletion of miR-146a enhances antiviral response in HIV-1 infected cells

Distinct susceptibility of HIV vaccine vector-induced CD4 T cells to HIV infection

HIV-1 inhibition in cells with CXCR4 mutant genome created by CRISPR-Cas9 and piggyBac recombinant technologies

IFN-λs inhibit Hantaan virus infection through the JAK-STAT pathway and expression of Mx2 protein

Evaluation of Antibody-Dependent Enhancement of SARS-CoV Infection in Rhesus Macaques Immunized with an Inactivated SARS-CoV Vaccine

Lack of association between integrin αvβ3 gene polymorphisms and hemorrhagic fever with renal syndrome in Han Chinese from Hubei, China

Molecular diagnosis of central nervous system opportunistic infections and mortality in HIV-infected adults in Central China

Genome modification of CXCR4 by Staphylococcus aureus Cas9 renders cells resistance to HIV-1 infection

Soybean-derived Bowman-Birk inhibitor (BBI) blocks HIV entry into macrophages

Genome editing of the HIV co-receptors CCR5 and CXCR4 by CRISPR-Cas9 protects CD4+ T cells from HIV-1 infection

Priming and Activation of Inflammasome by Canarypox Virus Vector ALVAC via the cGAS/IFI16–STING–Type I IFN Pathway and AIM2 Sensor

Antiviral activity of arbidol hydrochloride against herpes simplex virus I in vitro and in vivo

HTNV-induced upregulation of miR-146a in HUVECs promotes viral infection by modulating pro-inflammatory cytokine release

Phylogenetic analysis based on mitochondrial DNA sequences of wild rats, and the relationship with Seoul virus infection in Hubei, China

Sequential Dysfunction and Progressive Depletion of Candida albicans-Specific CD4 T Cell Response in HIV-1 Infection

Soybean-derived Bowman-Birk Inhibitor (BBI) Inhibits HIV Replication in Macrophages

pH-dependent conformational changes of a Thogoto virus matrix protein reveal mechanisms of viral assembly and uncoating

Specific interference shRNA-expressing plasmids inhibit Hantaan virus infection in vitro and in vivo

PLGA-PEG Nanoparticles Coated with Anti-CD45RO and Loaded with HDAC Plus Protease Inhibitors Activate Latent HIV and Inhibit Viral Spread

Genome editing of CXCR4 by CRISPR/cas9 confers cells resistant to HIV-1 infection

Influence of HLA-DRB alleles on haemorrhagic fever with renal syndrome in a Chinese Han population in Hubei Province, China

The Epidemic Characteristics and Changing Trend of Hemorrhagic Fever with Renal Syndrome in Hubei Province, China

The association of HLA-DRB1 alleles and drug use with HIV infection in a Chinese Han Cohort

In Vitro and in Vivo Studies of the Inhibitory Effects of Emodin Isolated from Polygonum cuspidatum on Coxsakievirus B4

Jiawei-Yupingfeng-Tang, a Chinese herbal formula, inhibits respiratory viral infections in vitro and in vivo

Antiviral and anti-inflammatory activity of arbidol hydrochloride in influenza A (H1N1) virus infection

CD56+ T cells inhibit HIV-1 infection of macrophages

Establishment of SYBR green-based qPCR assay for rapid evaluation and quantification for anti-Hantaan virus compounds in vitro and in suckling mice

Amelioration of influenza virus-induced reactive oxygen species formation by epigallocatechin gallate derived from green tea

Genetic characterization of a new subtype of Hantaan virus isolated from a hemorrhagic fever with renal syndrome (HFRS) epidemic area in Hubei Province, China

L-Ficolin Binds to the Glycoproteins Hemagglutinin and Neuraminidase and Inhibits Influenza A Virus Infection Both in vitro and in vivo

The Inhibitory Effect of Rheum palmatum Against Coxsackievirus B3in Vitro and in Vivo

CTLA-4基因单倍型与吸毒合并HIV感染的相关性研究

细胞毒T淋巴细胞相关抗原4基因多态性与吸毒并HIV感染相关

吸毒合并HIV感染与HLA-DRB1*1301/1302等位基因的相关性

HLA-DRB1基因多态性与吸毒合并HIV感染的相关性

Genetic analysis of hantaviruses and their rodent hosts in central-south China

Toll样受体与HIV-1病毒感染