百晓学者学者目录

康亮

副教授、教授，上海第二工业大学

精选作品

期刊论文

2026

基于Transformer-BILSTM耦合模型的TBM掘进速度预测研究

康亮，唐明阳，郝俊锁，宁赋岩

《铁道建筑技术》

2026

A Multi-omic atlas identifies osteopontin-expressing macrophages as drivers of intervertebral disc degeneration

Qiuwei Li, Liang Kang, Kai-Da Bo, Pei-Lin Jin, Chenhao Zhao, Renjie Zhang, Cai-Liang Shen

Genes & Diseases

DOI

2026

Hounsfield unit measurements from different regions of interest in lumbar spine CT: correlation with DEXA-derived bone mineral density and fracture status

Zeng-Kai Zhou, Jia-Qi Wang, Lu-Ping Zhou, Yu Chen, Pei-Lin Jin, Xin-Yu Dong, Hua-Qing Zhang, Chong-Yu Jia, Liang Kang, Hui-Ya Ma, Cai-Liang Shen, Ren-Jie Zhang

BMC Musculoskeletal Disorders

DOI

2026

MANF safeguards mitochondria-associated endoplasmic reticulum membrane integrity in nucleus pulposus-derived mesenchymal stem cells to maintain homeostasis of the intervertebral disc

Chen-Hao Zhao, Liang Kang, Jia-Qi Wang, Yan-Xin Wang, Yu Chen, Lu-Ping Zhou, Chong-Yu Jia, Hua-Qing Zhang, Jing-Yu Zhang, Zhi-Wei Chen, Ren-Jie Zhang, Cai-Liang Shen

Cell Biology and Toxicology

DOI

2026

Which vertebral levels provide practical HU-based assessment for osteoporosis screening? A comparative analysis from T1 to S2

Zeng-Kai Zhou, Yan-Yan Hou, Xin-Yu Dong, Jia-Qi Wang, Lu-Ping Zhou, Yu Chen, Pei-Lin Jin, Hua-Qing Zhang, Chong-Yu Jia, Liang Kang, Hui-Ya Ma, Cai-Liang Shen, Ren-Jie Zhang

Journal of Orthopaedic Surgery and Research

DOI

2026

Acid-sensing ion channel 1a contributes to the calcium/calmodulin-dependent ferroptosis and aggravates intervertebral disc degeneration

Lu-Ping Zhou, Jia-Qi Wang, Liang Kang, Yan-Yan Hou, Xu Yan, Chen-Hao Zhao, Chong-Yu Jia, Hua-Qing Zhang, Ren-Jie Zhang, Cai-Liang Shen

Redox Report

DOI

2026

Single-cell and spatial transcriptomics characterisation of RSPO2+ nucleus pulposus cells reveals a WNT/FN1–CD44 degenerative axis and therapeutic targets in IVDD

Qiu-Wei Li, Guoyan Liang, Kai-Da Bo, Liang Kang, Pei-Lin Jin, Chen-Hao Zhao, Ren-Jie Zhang, Feng-Juan Lyu, Cai-Liang Shen

Journal of Orthopaedic Translation

DOI

2026

DangGui NianTong Decoction attenuates intervertebral disc degeneration by mitigating nucleus pulposus cell senescence and apoptosis through autophagy induction.

Xu Yan, Ren-Jie Zhang, Yi-Bo Zhou, Hua-Qing Zhang, Rick F. Thorne, Xu-Dong Zhang, Chong-Yu Jia, Liang Kang, Lu-Ping Zhou, Xiao-Ying Liu, Cai-Liang Shen

Phytomedicine

DOI

2025

工业机器人数字孪生系统研究

蔡宝，康亮，顾鸿良

《自动化与仪表》

DOI

2025

复杂电子系统保障效能评估方法研究

王柔溪，刘书元，周委璇，康亮

《中国电子科学研究院学报》

2025

RBX1 mitigates ferroptosis by inhibiting NCOA4-mediated ferritinophagy and contributes to the attenuation of intervertebral disc degeneration

Lu-Ping Zhou, Liang Kang, Zhi-Gang Zhang, Chong-Yu Jia, Chen-Hao Zhao, Xian-Liang Zhang, Hua-Qing Zhang, Ren-Jie Zhang, Cai-Liang Shen

Journal of Translational Medicine

DOI

2025

PACS‐2 Mitigates NPSC Apoptosis and Intervertebral Disc Degeneration by Preserving MAM Integrity via the SP1/LRRK2/Mfn2 Axis

Liang Kang, Jiaqi Wang, Chenhao Zhao, Qiuwei Li, Zhigang Zhang, Hua-Qing Zhang, Chong-Yu Jia, Luping Zhou, Yan-Xin Wang, Yu Chen, Kaixuan Li, Xu Yan, Jie Fang, Haibao Wang, Dandan Wang, Pingping Su, Jing-Yu Zhang, Zhi-Wei Chen, Renjie Zhang, Cai-Liang Shen

Advancement of science

DOI

2025

FSTL1 accelerates nucleus pulposus-derived mesenchymal stem cell apoptosis in intervertebral disc degeneration by activating TGF-β-mediated Smad2/3 phosphorylation

Xu Yan, Jing-Yu Ding, Ren-Jie Zhang, Yan-Xin Wang, Lu-Ping Zhou, Hua-Qing Zhang, Liang Kang, Chong-Yu Jia, Xiao-Ying Liu, Cai-Liang Shen

Journal of Translational Medicine

DOI

2025

Vertebral bone quality score as a novel tool for bone mineral density assessment: which measurement approach is more accurate?

Zeng-Kai Zhou, Jia-Qi Wang, Kiyimba Daniel Mwesigwa, Yu Chen, Pei-Lin Jin, Xin-Yu Dong, Hua-Qing Zhang, Lu-Ping Zhou, Chong-Yu Jia, Liang Kang, Hui-Ya Ma, Cai-Liang Shen, Ren-Jie Zhang

European spine journal

DOI

2025

ASIC1a Promotes nucleus pulposus derived stem cells apoptosis through modulation of SIRT3-dependent mitochondrial redox homeostasis in intervertebral disc degeneration

Zhi-Gang Zhang, Liang Kang, Lu-Ping Zhou, Yan-Xin Wang, Chong-Yu Jia, Chen-Hao Zhao, Bo Zhang, Jia-Qi Wang, Hua-Qing Zhang, Ren-Jie Zhang, Cai-Liang Shen

Redox Report

DOI

2025

Design and radiological confirmation of three-column cortical bone trajectory in the lower thoracic vertebrae

Ren-Jie Zhang, Jiaqi Wang, Lu-Ping Zhou, Chong-Yu Jia, Hua-Qing Zhang, Liang Kang, Cai-Liang Shen

European spine journal

DOI

2024

Comparison of robotic or computer-assisted navigation versus fluoroscopic freehand techniques in the accuracy of posterior cervical screw placement during cervical spine surgery: a meta-analysis.

Lu-Ping Zhou, Ren-Jie Zhang, Yi Shang, Chen-Hao Zhao, Liang Kang, Chong-Yu Jia, Jia-Qi Wang, Hua-Qing Zhang, Cai-Liang Shen

Journal of Neurosurgery : Spine

DOI

2024

Diagnostic value of serum COMP and ADAMTS7 for intervertebral disc degeneration

Jing-Yu Ding, Xu Yan, Ren-Jie Zhang, Hua-Qing Zhang, Liang Kang, Chong-Yu Jia, Rick F. Thorne, Xiao-Ying Liu, Cai-Liang Shen

European Journal of Medical Research

DOI

2024

FSTL1 Accelerates Nucleus Pulposus Cell Senescence and Intervertebral Disc Degeneration Through TLR4/NF-κB Pathway

Xu Yan, Jing-Yu Ding, Ren-Jie Zhang, Hua-Qing Zhang, Liang Kang, Chong-Yu Jia, Xiao-Ying Liu, Cai-Liang Shen

Inflammation

DOI

2024

Letter to the Editor Regarding "A Comparison of Percutaneous Pedicle Screw Accuracy Between Robotic Navigation and Novel Fluoroscopy-Based Instrument Tracking for Patients Undergoing Instrumented Thoracolumbar Surgery".

Zhi-Gang Zhang, Lu-Ping Zhou, Liang Kang, Cailiang Shen

World Neurosurgery

DOI

2023

SLSL-QPSO: Quantum-behaved particle swarm optimization with short-lived swarm layers

Kang Liang, Zhang Xiukai, Олег Крахмалев

SoftwareX

DOI

2023

Which Indicator Among Lumbar Vertebral Hounsfield Unit, Vertebral Bone Quality, or Dual-Energy X-Ray Absorptiometry-Measured Bone Mineral Density Is More Efficacious in Predicting Thoracolumbar Fragility Fractures?

Bo Zhang, Lu-Ping Zhou, Xian-Liang Zhang, Dui Li, Jia-Qi Wang, Chong-Yu Jia, Hua-Qing Zhang, Liang Kang, Ren-Jie Zhang, Cai-Liang Shen

Neurospine

DOI

2023

Clinical application of spinal robot in cervical spine surgery: safety and accuracy of posterior pedicle screw placement in comparison with conventional freehand methods

Lu-Ping Zhou, Ren-Jie Zhang, Wen-Kui Zhang, Liang Kang, Kai-xuan Li, Hua-Qing Zhang, Chong-Yu Jia, Yin-Shun Zhang, Cai-Liang Shen

Neurosurgical review

DOI

2023

Comparative effectiveness of nonpharmacological interventions in reducing psychological symptoms among patients with chronic low back pain

Lu-Ping Zhou, Ren-Jie Zhang, Jin Shang, Liang Kang, Zhi-Gang Zhang, Bo Zhang, Jia-Qi Wang, Chong-Yu Jia, Chen-Hao Zhao, Huan Zhang, Xian-Liang Zhang, Cai-Liang Shen

International Journal of Surgery

DOI

2023

Biomechanical Study of 3 Osteoconductive Materials Applied in Pedicle Augmentation and Revision for Osteoporotic Vertebrae: Allograft Bone Particles, Calcium Phosphate Cement, Demineralized Bone Matrix

Chong-Yu Jia, Ren-Jie Zhang, Jia-Qi Wang, Bo Zhang, Hua-Qing Zhang, Liang Kang, Lu-Ping Zhou, Cai-Liang Shen

Neurospine

DOI

2023

Epigenetic Modifications of Inflammation in Intervertebral Disc Degeneration.

Liang Kang, Hua-Qing Zhang, Chong-Yu Jia, Renjie Zhang, Cai-Liang Shen

Ageing Research Reviews

DOI

2022

喷码机器人字符库的设计及应用

谭晓杰，郝晓东，康亮，边岩

《冶金自动化》

2022

Ferroptosis: A potential target for the intervention of intervertebral disc degeneration

Lu-Ping Zhou, Ren-Jie Zhang, Chong-Yu Jia, Liang Kang, Zhi-Gang Zhang, Hua-Qing Zhang, Jiaqui Wang, Bo Zhang, Cai-Liang Shen

Frontiers in Endocrinology

DOI

2022

Targeting Oxidative Stress and Inflammation in Intervertebral Disc Degeneration: Therapeutic Perspectives of Phytochemicals

Liang Kang, Hua-Qing Zhang, Chong-Yu Jia, Ren-Jie Zhang, Cai-Liang Shen

Frontiers in Pharmacology

DOI

2020

基于ARM Cortex-M7内核的配电自动化终端设计

郑贵林，康亮

《仪表技术与传感器》

2020

CircCOG8 Downregulation Contributes to the Compression-Induced Intervertebral Disk Degeneration by Targeting miR-182-5p and FOXO3

Q. Xiang, Liang Kang, K. Zhao, Jun-Tan Wang, Wen-Bin Hua, Yu Song, Xiao-Bo Feng, Gao-Cai Li, Saideng Lu, Kun Wang, Cao Yang, Yu-Kun Zhang

Frontiers in Cell and Developmental Biology

DOI

2020

CircRNA-CIDN mitigated compression loading-induced damage in human nucleus pulposus cells via miR-34a-5p/SIRT1 axis

Q. Xiang, Liang Kang, Jun-Tan Wang, Zhi-Wei Liao, Yu Song, K. Zhao, Kun Wang, Cao Yang, Yu-Kun Zhang

EBioMedicine

DOI

2019

Restoration of Autophagic Flux Rescues Oxidative Damage and Mitochondrial Dysfunction to Protect against Intervertebral Disc Degeneration

Liang Kang, Q. Xiang, Shengfeng Zhan, Yu Song, Kun Wang, K. Zhao, Shuai Li, Zengwu Shao, Cao Yang, Yu-Kun Zhang

Oxidative Medicine and Cellular Longevity

DOI

2019

Emerging Roles of Circular RNA in Compression Loading-Induced Damage in Human Nucleus Pulposus Cells

Q. Xiang, Liang Kang, Jun-Tan Wang, Zhi-Wei Liao, Yu Song, K. Zhao, Kun Wang, Cao Yang, Yu-Kun Zhang

Social Science Research Network

DOI

2018

Autophagy attenuates compression‐induced apoptosis of human nucleus pulposus cells via MEK/ERK/NRF1/Atg7 signaling pathways during intervertebral disc degeneration

Shuai Li, Wen-Bin Hua, Kun Wang, Yong Gao, Songfeng Chen, Wei Liu, Yu Song, Xing-Huo Wu, Ji Tu, Liang Kang, K. Zhao, Liming Xiong, Yu-Kun Zhang, Cao Yang

Experimental Cell Research

DOI

2018

Sirtuin 3-dependent mitochondrial redox homeostasis protects against AGEs-induced intervertebral disc degeneration

Yu Song, Shuai Li, Wen Geng, Rongjin Luo, W. Liu, Ji Tu, Kun Wang, Liang Kang, Huipeng Yin, Xing-Huo Wu, Yong Gao, Yu-Kun Zhang, Cao Yang

Redox Biology

DOI

2018

Sestrin-Mediated Inhibition of Stress-Induced Intervertebral Disc Degradation Through the Enhancement of Autophagy

Ji Tu, Wen-Tian Li, Shuai Li, Wei Liu, Yu-Kun Zhang, Xing-Huo Wu, Rongjin Luo, Wen-Bin Hua, Kun Wang, Yu Song, Liang Kang, Wen Yang, Shu-hua Yang, Cao Yang

Cellular Physiology and Biochemistry

DOI

2018

The involvement of regulated in development and DNA damage response 1 (REDD1) in the pathogenesis of intervertebral disc degeneration

Huipeng Yin, Yu-Kun Zhang, Kun Wang, Yu Song, Ji Tu, Liang Kang, K. Zhao, Xing-Huo Wu, Rongjin Luo, Cao Yang

Experimental Cell Research

DOI

2018

Short-term effects of minimally invasive dynamic neutralization system for the treatment of lumbar spinal stenosis

Ji Tu, Wen-Bin Hua, Wen-Tian Li, Wei Liu, Rongjin Luo, Shuai Li, Yu-Kun Zhang, Liang Kang, Kun Wang, Yu Song, Shuahua Yang, Cao Yang

Medicine

DOI

2018

Angiopoietin-2 promotes extracellular matrix degradation in human degenerative nucleus pulposus cells.

Kun Wang, Liang Kang, Wei Liu, Yu Song, Xing-Huo Wu, Yu-Kun Zhang, Wen-Bin Hua, K. Zhao, Shuai Li, Ji Tu, Rongjin Luo, Cao Yang

International Journal of Molecular Medicine

DOI

2017

Dysregulated miR-127-5p contributes to type II collagen degradation by targeting matrix metalloproteinase-13 in human intervertebral disc degeneration.

Wen-Bin Hua, Xing-Huo Wu, Yu-Kun Zhang, Yu Song, Ji Tu, Liang Kang, K. Zhao, Shuai Li, Kun Wang, Wei Liu, Zeng-Wu Shao, Shu-hua Yang, Cao Yang

Biochimie

DOI

2017

The noncoding RNA linc-ADAMTS5 cooperates with RREB1 to protect from intervertebral disc degeneration through inhibiting ADAMTS5 expression.

Kun Wang, Yu Song, Wei Liu, Xing-Huo Wu, Yu-Kun Zhang, Shuai Li, Liang Kang, Ji Tu, K. Zhao, Wen-Bin Hua, Cao Yang

Clinical science

DOI

2017

MicroRNA-15b silencing inhibits IL-1β-induced extracellular matrix degradation by targeting SMAD3 in human nucleus pulposus cells

Liang Kang, Cao Yang, Huipeng Yin, K. Zhao, Wei Liu, Wen-Bin Hua, Kun Wang, Yu Song, Ji Tu, Shuai Li, Rongjin Luo, Yu-Kun Zhang

Biotechnology Letters

DOI

2017

Epigenetic silencing of miRNA-143 regulates apoptosis by targeting BCL2 in human intervertebral disc degeneration.

K. Zhao, Yu-Kun Zhang, Liang Kang, Yu Song, Kun Wang, Shuai Li, Xing-Huo Wu, Wen-Bin Hua, Zengwu Shao, Shu-hua Yang, Cao Yang

Gene

DOI

2017

Sirtuin 6 prevents matrix degradation through inhibition of the NF‐&kgr;B pathway in intervertebral disc degeneration

Liang Kang, Jia Hu, Yu-xiong Weng, J. Jia, Yu-Kun Zhang

Experimental Cell Research

DOI

2017

MicroRNA‐132 upregulation promotes matrix degradation in intervertebral disc degeneration

Wei Liu, Ping Xia, Jing Feng, Liang Kang, Mi Huang, Kun Wang, Yu Song, Shuai Li, Xing-Huo Wu, Shu-hua Yang, Cao Yang

Experimental Cell Research

DOI

2017

Methylation of microRNA-129-5P modulates nucleus pulposus cell autophagy by targeting Beclin-1 in intervertebral disc degeneration

K. Zhao, Yu-Kun Zhang, Liang Kang, Yu Song, Kun Wang, Shuai Li, Xing-Huo Wu, Wen-Bin Hua, Zengwu Shao, Shu-hua Yang, Cao Yang

OncoTarget

DOI

2017

Advanced glycation end products regulate anabolic and catabolic activities via NLRP3‐inflammasome activation in human nucleus pulposus cells

Yu Song, Yan Wang, Yu-Kun Zhang, Wen Geng, Wei Liu, Yong Gao, Shuai Li, Kun Wang, Xing-Huo Wu, Liang Kang, Cao Yang

Journal of Cellular and Molecular Medicine

DOI

2017

Icariin Attenuates Interleukin-1β-Induced Inflammatory Response in Human Nucleus Pulposus Cells.

Wen-Bin Hua, Yu-Kun Zhang, Xing-Huo Wu, Liang Kang, Ji Tu, K. Zhao, Shuai Li, Kun Wang, Yu Song, Rongjin Luo, Zengwu Shao, Shu-hua Yang, Cao Yang

Current pharmaceutical design

DOI

2017

Simvastatin Inhibits IL-1β-Induced Apoptosis and Extracellular Matrix Degradation by Suppressing the NF-kB and MAPK Pathways in Nucleus Pulposus Cells

Ji Tu, Wen-Tian Li, Yu-Kun Zhang, Xing-Huo Wu, Yu Song, Liang Kang, Wei Liu, Kun Wang, Shuai Li, Wen-Bin Hua, Cao Yang

Inflammation

DOI

2017

MicroRNA-494 promotes apoptosis and extracellular matrix degradation in degenerative human nucleus pulposus cells

Liang Kang, Cao Yang, Yu Song, K. Zhao, Wei Liu, Wen-Bin Hua, Kun Wang, Ji Tu, Shuai Li, Huipeng Yin, Yu-Kun Zhang

OncoTarget

DOI

2016

MicroRNA-23a-3p promotes the development of osteoarthritis by directly targeting SMAD3 in chondrocytes.

Liang Kang, Cao Yang, Yu Song, Wei Liu, Kun Wang, Shuai Li, Yu-Kun Zhang

Biochemical and Biophysical Research Communications - BBRC

DOI

2011

自动化立体仓库的应用与物流发展的灰色关联分析

康亮，杨坚争，康明

《现代科学仪器》

2009

未知环境下改进的基于RRT算法的移动机器人路径规划

康亮，赵春霞，郭剑辉

《模式识别与人工智能》

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