谭何新｜河南中医药大学｜学者主页

2025

Single-nucleus transcriptomics reveal the morphogenesis and artemisinin biosynthesis in Artemisia annua glandular trichomes

Minghui Zhang, Mingyu Li, Ya-ling An, Chang Liu, Qiaojuan Zhao, Dan-Feng Zhang, Baiwei Pan, Hexin Tan

Nature Communications

DOI

2025

Regulation of important natural products biosynthesis by WRKY transcription factors in plants

Mingyu Li, Yiming Shao, Baiwei Pan, Chang Liu, Hexin Tan

Journal of Advanced Research

DOI

2025

[Function of flavoprotein monooxygenases in natural product biosynthesis].

Mengya Cheng, Chang Liu, Hexin Tan

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica

DOI

2025

Two Isatis Genomes Reveal the Biosynthesis and Evolutionary Origin of Indigo in Plants.

Jun-Feng Chen, Hexin Tan, Jun Yang, Kai-Jian Zhang, Rongrong Li, Shi Qiu, Dou-Dou Huang, Zong-You Lv, Zhi-Chao Xu, Qing Li, Zhong-Ming Xu, Ping Zhao, Jingxian Feng, Yajing Li, Wei Sun, Fei Yang, Ru-Feng Wang, Lei Zhang, Ying Xiao, Wan-Sheng Chen

Genomics, Proteomics & Bioinformatics

DOI

2024

黄素蛋白单加氧酶在天然产物生物合成中的功能研究

程梦雅，刘畅，谭何新

《中国中药杂志》

2024

Glandular trichomes: the factory of artemisinin biosynthesis

Qiaojuan Zhao, Mingyu Li, Minghui Zhang, Hexin Tan

Medicinal Plant Biology

DOI

2023

Correction: Identification of novel flavin-dependent monooxygenase from Strobilanthes Cusia reveals molecular basis of indoles’ biosynthetic logic

Chang Liu, Mengya Cheng, Chao Ma, Junfeng Chen, Hexin Tan

BMC Plant Biology

DOI

2023

Genome-wide identification and characterisation of bHLH transcription factors in Artemisia annua

Shu-Ying Chang, Qi Li, Bao-Kang Huang, Wan-Sheng Chen, Hexin Tan

BMC Plant Biology

DOI

2023

Identification of novel flavin-dependent monooxygenase from Strobilanthes Cusia reveals molecular basis of indoles’ biosynthetic logic

Chang Liu, Mengya Cheng, Chao Ma, Jun-Feng Chen, Hexin Tan

BMC Plant Biology

DOI

2023

Molecular cloning and functional characterization of BcTSA in the biosynthesis of indole alkaloids in Baphicacanthus cusia

Zhi-Ying Guo, Jun-Feng Chen, Zong-You Lv, Yuxiang Huang, Hexin Tan, Lei Zhang, Yong Diao

Frontiers in Plant Science

DOI

2023

Effects of exogenous indole‐3‐acetic acid on the density of trichomes, expression of artemisinin biosynthetic genes, and artemisinin biosynthesis in Artemisia annua

Zhi-Ying Guo, Q. Zhang, Yitong Zhang, Chang-Yu Wu, Yi Zheng, F. Tong, Linhui Zhang, Ruyu Lu, Xiusong Pan, Hexin Tan, Zong-You Lv

Biotechnology and applied biochemistry

DOI

2022

5E教学模式在中药鉴定学课程教学中的应用——以叶类中药为例

刘畅，王宏瑞，张成中，谭何新

《中医药管理杂志》

2021

黄花蒿R2R3-MYB转录因子全基因组鉴定及生物信息学分析

李琦，王怡超，刘畅，谭何新

《生物技术通报》

DOI

2020

IiWRKY34 positively regulates yield, lignan biosynthesis and stress tolerance in Isatis indigotica

Ying Xiao, Jin Feng, Qing Li, Yang-Yun Zhou, Qitao Bu, Jun-Hui Zhou, Hexin Tan, Yingbo Yang, Lei Zhang, Wan-Sheng Chen

Acta Pharmaceutica Sinica B

DOI

2020

Author Correction: SmMYC2a and SmMYC2b played similar but irreplaceable roles in regulating the biosynthesis of tanshinones and phenolic acids in Salvia miltiorrhiza

Yang-Yun Zhou, Wei Sun, Jun-Feng Chen, Hexin Tan, Ying Xiao, Qing Li, Q. Ji, Shou-Hong Gao, Li Chen, Shilin Chen, Lei Zhang, Wan-Sheng Chen

Scientific Reports

DOI

2020

ICHOME AND ARTEMISININ REGULATOR 2 positively regulates trichome development and artemisinin biosynthesis in Artemisia annua.

Zheng Zhou, Hexin Tan, Qi Li, Qing Li, Yun Wang, Qitao Bu, Yao Li, Yu Wu, Wan-Sheng Chen, Lei Zhang

New Phytologist

DOI

2019

PBL教学法在药学专业中医药学基础课程中的应用探索

陈啸飞，季倩，谭何新，卜其涛，张磊

《卫生职业教育》

2019

西红花MADS-box基因家族的生物信息学分析

张一菡，李卿，张磊，谭何新，陈祥慧

《基因组学与应用生物学》

DOI

2019

Molecular cloning and metabolomic characterization of the 5-enolpyruvylshikimate-3-phosphate synthase gene from Baphicacanthus cusia

Jian Yu, Yi-Han Zhang, Shu-Ju Ning, Qi Ye, Hexin Tan, Ruibing Chen, Qitao Bu, Rui Zhang, Peimin Gong, Xiaoli Ma, Lei Zhang, Dao-Zhi Wei

BMC Plant Biology

DOI

2019

Transcriptome analysis reveals novel enzymes for apo-carotenoid biosynthesis in saffron and allows construction for crocetin synthesis in yeast.

Hexin Tan, Xianghui Chen, Nan Liang, Ruibing Chen, Jun-Feng Chen, Chao-Yang Hu, Qi Li, Qing Li, Wei-Zhong Pei, Wen-hui Xiao, Ying-Jin Yuan, Wan-Sheng Chen, Lei Zhang

Journal of Experimental Botany

DOI

2019

Molecular Mechanisms and Gene Regulation for Biosynthesis of Medicinal Plant Active Ingredients

Lei Zhang, Hexin Tan, P. Zerbe

Molecular Pharmacognosy

DOI

2019

Genome-Wide Identification and Characterization of Salvia miltiorrhiza Laccases Reveal Potential Targets for Salvianolic Acid B Biosynthesis

Qing Li, Jin Feng, Liang Chen, Zhichao Xu, Ying-Jie Zhu, Yun Wang, Ying Xiao, Jun-Feng Chen, Yang-Yun Zhou, Hexin Tan, Lei Zhang, Wan-Sheng Chen

Frontiers in Plant Science

DOI

2018

西红花中类胡萝卜素生物合成途径研究进展

陈祥慧，谭何新，张磊

《中草药》

2018

Targeted expression of Vitreoscilla hemoglobin improves the production of tropane alkaloids in Hyoscyamus niger hairy roots

Zhi-Ying Guo, Hexin Tan, Zong-You Lv, Q. Ji, Yuxiang Huang, Jing-Jing Liu, Donghong Chen, Y. Diao, J. Si, Lei Zhang

Scientific Reports

DOI

2018

[Bioinformation analysis of chorismate synthase in Baphicacantus cusia and other 78 species of plants].

Jian Yu, Qi Ye, Shu-Ju Ning, Qing Li, Hexin Tan, Jingzhang Feng, Ruibing Chen, Xiaoli Ma, Peimin Gong, Xuanxuan Zhao, Lei Zhang, Dao-Zhi Wei

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica

DOI

2018

CRISPR/Cas9-mediated efficient targeted mutagenesis of RAS in Salvia miltiorrhiza.

Zheng Zhou, Hexin Tan, Qing Li, Jun-Feng Chen, Shou-Hong Gao, Yun Wang, Wansheng Chen, Lei Zhang

Phytochemistry

DOI

2018

Integrated Transcript and Metabolite Profiles Reveal That EbCHI Plays an Important Role in Scutellarin Accumulation in Erigeron breviscapus Hairy Roots

Ruibing Chen, Xianghui Chen, Tingting Zhu, Jianghua Liu, Xing Xiang, Jian Yu, Hexin Tan, Shou-Hong Gao, Qing Li, Yi Fang, Wan-Sheng Chen, Lei Zhang, Bao-Kang Huang

Frontiers in Plant Science

DOI

2017

有效成分生源途径解析与调控技术在中药材生产实践中具有广阔应用前景

张磊，陈军峰，肖莹，谭何新，李卿，陈万生

《世界科学技术-中医药现代化》

2017

高通量代谢组学在药用植物研究中的应用

郭志英，周正，谭何新，张磊，刁勇

《药学实践与服务》

2017

马蓝种质资源研究进展

周正，郭志英，谭何新，刘佳颖，刁勇，张磊

《药学实践与服务》

2017

HPPR encodes the hydroxyphenylpyruvate reductase required for the biosynthesis of hydrophilic phenolic acids in Salvia miltiorrhiza.

Guo-Quan Wang, Jun-feng Chen, B. Yi, Hexin Tan, Lei Zhang, Wan-Sheng Chen

Chinese Journal of Natural Medicines

DOI

2017

[Molecular mechanism of artemisinin biosynthesis and regulation in Artemisia annua].

Hexin Tan, Ling Xiao, Zheng Zhou, Lei Zhang, Wan-Sheng Chen

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica

DOI

2017

AP2/ERF Transcription Factor, Ii049, Positively Regulates Lignan Biosynthesis in Isatis indigotica through Activating Salicylic Acid Signaling and Lignan/Lignin Pathway Genes

Rui-Fang Ma, Ying Xiao, Zong-You Lv, Hexin Tan, Ruibing Chen, Qing Li, Jun-Feng Chen, Yun Wang, Jun Yin, Lei Zhang, Wan-Sheng Chen

Frontiers in Plant Science

DOI

2017

Stable Internal Reference Genes for Normalizing Real-Time Quantitative PCR in Baphicacanthus cusia under Hormonal Stimuli and UV Irradiation, and in Different Plant Organs

Yuxiang Huang, Hexin Tan, Jian Yu, Yue Chen, Zhi-Ying Guo, Guo-Quan Wang, Qinglei Zhang, Jun-Feng Chen, Lei Zhang, Y. Diao

Frontiers in Plant Science

DOI

2016

吲哚生物碱生物合成研究进展

陈越，张青磊，黄玉香，谭何新，刁勇，张磊

《世界科学技术-中医药现代化》

2016

药用植物学理论教学策略探讨

谭何新，季倩，陈啸飞，张汉明，李红方，张磊

《基础医学教育》

2016

药用植物学天目山野外实习教学探讨

谭何新，陈啸飞，季倩，张汉明，李红方，张磊

《基础医学教育》

2016

Artemisia annua glandular secretory trichomes: the biofactory of antimalarial agent artemisinin

Ling Xiao, Hexin Tan, Lei Zhang

DOI

2016

The biosynthesis and genetic engineering of bioactive indole alkaloids in plants

Yuxiang Huang, Hexin Tan, Zhi-Ying Guo, Xunxun Wu, Qinglei Zhang, Lei Zhang, Y. Diao

Journal of Plant Biology

DOI

2016

Dynamic metabolic and transcriptomic profiling of methyl jasmonate‐treated hairy roots reveals synthetic characters and regulators of lignan biosynthesis in Isatis indigotica Fort

Lei Zhang, Jun-Feng Chen, Xun Zhou, Xiao-Fei Chen, Qing Li, Hexin Tan, Xin Dong, Ying Xiao, Lang-Dong Chen, Wan-Sheng Chen

Plant Biotechnology Journal

DOI

2016

薬用植物アルカロイドの二次代謝工学研究の進展【JST・京大機械翻訳】

Yuxiang Huang, Hexin Tan, Jian Yu, Qinglei Zhang, Zhi-Ying Guo, Yue Chen, Y. Diao, Lei Zhang

2016

SmMYC2a and SmMYC2b played similar but irreplaceable roles in regulating the biosynthesis of tanshinones and phenolic acids in Salvia miltiorrhiza

Yang-Yun Zhou, Wei Sun, Jun-Feng Chen, Hexin Tan, Ying Xiao, Qing Li, Q. Ji, Shou-Hong Gao, Li Chen, Shilin Chen, Lei Zhang, Wan-Sheng Chen

Scientific Reports

DOI

2015

Gene-to-metabolite network for biosynthesis of lignans in MeJA-elicited Isatis indigotica hairy root cultures

Ruibing Chen, Qing Li, Hexin Tan, Jun-Feng Chen, Ying Xiao, Rui-Fang Ma, Shou-Hong Gao, P. Zerbe, Wan-Sheng Chen, Lei Zhang

Frontiers in Plant Science

DOI

2015

Deep Sequencing Reveals the Effect of MeJA on Scutellarin Biosynthesis in Erigeron breviscapus

Rui-Bing Chen, Jiang-Hua Liu, Ying Xiao, Feng Zhang, Jun-feng Chen, Q. Ji, Hexin Tan, Xin Huang, Hao Feng, Bao-Kang Huang, Wan-Sheng Chen, Lei Zhang

PLoS ONE

DOI

2015

Combined transcriptome and metabolite profiling reveals that IiPLR1 plays an important role in lariciresinol accumulation in Isatis indigotica

Ying Xiao, Q. Ji, Shou-Hong Gao, Hexin Tan, Ruibing Chen, Qing Li, Jun-Feng Chen, Yingbo Yang, Lei Zhang, Zheng-Tao Wang, Wan-Sheng Chen, Zhibi Hu

Journal of Experimental Botany

DOI

2015

TRICHOME AND ARTEMISININ REGULATOR 1 Is Required for Trichome Development and Artemisinin Biosynthesis in Artemisia annua.

Hexin Tan, Ling Xiao, Shou-Hong Gao, Qing Li, Jun-Feng Chen, Ying Xiao, Q. Ji, Ruibing Chen, Wan-Sheng Chen, Lei Zhang

Molecular Plant

DOI

2014

丹参果糖磷酸酶基因的克隆和功能研究(英文)

谭何新，刘颖，张磊

《药学实践与服务》

2013

¹³C tracer reveals phenolic acids biosynthesis in hairy root cultures of Salvia miltiorrhiza.

Peng Di, Lei Zhang, Jun-Feng Chen, Hexin Tan, Ying Xiao, Xin Dong, Xun Zhou, Wan-Sheng Chen

ACS Chemical Biology

DOI

精选作品

期刊论文

Single-nucleus transcriptomics reveal the morphogenesis and artemisinin biosynthesis in Artemisia annua glandular trichomes

Regulation of important natural products biosynthesis by WRKY transcription factors in plants

[Function of flavoprotein monooxygenases in natural product biosynthesis].

Two Isatis Genomes Reveal the Biosynthesis and Evolutionary Origin of Indigo in Plants.

黄素蛋白单加氧酶在天然产物生物合成中的功能研究

Glandular trichomes: the factory of artemisinin biosynthesis

Correction: Identification of novel flavin-dependent monooxygenase from Strobilanthes Cusia reveals molecular basis of indoles’ biosynthetic logic

Genome-wide identification and characterisation of bHLH transcription factors in Artemisia annua

Identification of novel flavin-dependent monooxygenase from Strobilanthes Cusia reveals molecular basis of indoles’ biosynthetic logic

Molecular cloning and functional characterization of BcTSA in the biosynthesis of indole alkaloids in Baphicacanthus cusia

Effects of exogenous indole‐3‐acetic acid on the density of trichomes, expression of artemisinin biosynthetic genes, and artemisinin biosynthesis in Artemisia annua

5E教学模式在中药鉴定学课程教学中的应用——以叶类中药为例

黄花蒿R2R3-MYB转录因子全基因组鉴定及生物信息学分析

IiWRKY34 positively regulates yield, lignan biosynthesis and stress tolerance in Isatis indigotica

Author Correction: SmMYC2a and SmMYC2b played similar but irreplaceable roles in regulating the biosynthesis of tanshinones and phenolic acids in Salvia miltiorrhiza

ICHOME AND ARTEMISININ REGULATOR 2 positively regulates trichome development and artemisinin biosynthesis in Artemisia annua.

PBL教学法在药学专业中医药学基础课程中的应用探索

西红花MADS-box基因家族的生物信息学分析

Molecular cloning and metabolomic characterization of the 5-enolpyruvylshikimate-3-phosphate synthase gene from Baphicacanthus cusia

Transcriptome analysis reveals novel enzymes for apo-carotenoid biosynthesis in saffron and allows construction for crocetin synthesis in yeast.

Molecular Mechanisms and Gene Regulation for Biosynthesis of Medicinal Plant Active Ingredients

Genome-Wide Identification and Characterization of Salvia miltiorrhiza Laccases Reveal Potential Targets for Salvianolic Acid B Biosynthesis

西红花中类胡萝卜素生物合成途径研究进展

Targeted expression of Vitreoscilla hemoglobin improves the production of tropane alkaloids in Hyoscyamus niger hairy roots

[Bioinformation analysis of chorismate synthase in Baphicacantus cusia and other 78 species of plants].

CRISPR/Cas9-mediated efficient targeted mutagenesis of RAS in Salvia miltiorrhiza.

Integrated Transcript and Metabolite Profiles Reveal That EbCHI Plays an Important Role in Scutellarin Accumulation in Erigeron breviscapus Hairy Roots

有效成分生源途径解析与调控技术在中药材生产实践中具有广阔应用前景

高通量代谢组学在药用植物研究中的应用

马蓝种质资源研究进展

HPPR encodes the hydroxyphenylpyruvate reductase required for the biosynthesis of hydrophilic phenolic acids in Salvia miltiorrhiza.

[Molecular mechanism of artemisinin biosynthesis and regulation in Artemisia annua].

AP2/ERF Transcription Factor, Ii049, Positively Regulates Lignan Biosynthesis in Isatis indigotica through Activating Salicylic Acid Signaling and Lignan/Lignin Pathway Genes

Stable Internal Reference Genes for Normalizing Real-Time Quantitative PCR in Baphicacanthus cusia under Hormonal Stimuli and UV Irradiation, and in Different Plant Organs

吲哚生物碱生物合成研究进展

药用植物学理论教学策略探讨

药用植物学天目山野外实习教学探讨

Artemisia annua glandular secretory trichomes: the biofactory of antimalarial agent artemisinin

The biosynthesis and genetic engineering of bioactive indole alkaloids in plants

Dynamic metabolic and transcriptomic profiling of methyl jasmonate‐treated hairy roots reveals synthetic characters and regulators of lignan biosynthesis in Isatis indigotica Fort

薬用植物アルカロイドの二次代謝工学研究の進展【JST・京大機械翻訳】

SmMYC2a and SmMYC2b played similar but irreplaceable roles in regulating the biosynthesis of tanshinones and phenolic acids in Salvia miltiorrhiza

Gene-to-metabolite network for biosynthesis of lignans in MeJA-elicited Isatis indigotica hairy root cultures

Deep Sequencing Reveals the Effect of MeJA on Scutellarin Biosynthesis in Erigeron breviscapus

Combined transcriptome and metabolite profiling reveals that IiPLR1 plays an important role in lariciresinol accumulation in Isatis indigotica

TRICHOME AND ARTEMISININ REGULATOR 1 Is Required for Trichome Development and Artemisinin Biosynthesis in Artemisia annua.

丹参果糖磷酸酶基因的克隆和功能研究(英文)

¹³C tracer reveals phenolic acids biosynthesis in hairy root cultures of Salvia miltiorrhiza.