徐焕｜延安大学｜学者主页

2026

Puerarin inhibits Benign prostatic hyperplasia through regulating HIF-1α-HIF-1β/ AKT1/AP-1.

Meng Gu, Tianye Yang, Qi Chen, Yan-Bo Chen, Chong Liu, Zhong Wang, Huan Xu, Bin Xu

Translational research : the journal of laboratory and clinical medicine

DOI

2025

基于卫星跟踪钳嘴鹳空间运动规律初报

徐焕，杨旭，雷宇，刘慧，刘强

《动物学杂志》

2025

不同磁场强度对白蚁运动行为和磁感应受体基因表达量的影响

高勇勇，徐焕，王文靖，雷忻，张延亿，邓刚，黄求应

《林业科学》

2025

社会性昆虫表型可塑性调控机制的研究进展

高勇勇，雷忻，徐焕

《延安大学学报(自然科学版)》

DOI

2025

菲对泥鳅运动活性及焦虑、社交行为的胁迫影响

张子焜，徐焕，高勇勇，高小鸽，唐绪，雷忻

《水产学报》

2025

Fibroblasts promote the progression of benign prostatic hyperplasia through colony-stimulating factor 1 receptor-mediated RTK signaling in prostatic epithelial cells

Ming Zhan, Rui-Feng Yang, Yue Gu, Jun Zhu, Miaomiao Guo, G. Pupwe, Xiaohua Huang, Huan Xu, Zhilian Jia, Kyle Takehiro, Chong Liu, Bingyu Li, Yi-Wei Wang, Yan-Bo Chen, Xian-Jin Wang, Qi Chen, Bin Xu

Molecular Biomedicine

DOI

2025

Integrating spatial transcriptomics and single-cell RNA-sequencing reveals epithelial cell alterations in benign prostatic hyperplasia following finasteride treatment

Yan-Ting Shen, Xia-Wei Fei, Liyang Dai, Ting-Shao Zhu, Ji-Can Liu, Zhen-Qi Wu, Huan Xu, Hui-Feng Li, Zhong Wang

Genes and Diseases

DOI

2025

Arctigenin inhibits high glucose-induced EMT and cell proliferation to alleviate benign prostatic hyperplasia companied with type 2 diabetes mellitus through MBOAT4/ acylated Ghrelin/GHS-R.

Meng Gu, Jianchao Ge, Huan Xu, Yan-Bo Chen, Qi Chen, Zhong Wang, Bin Xu

Chemico-Biological Interactions

DOI

2025

PD35-08 SHORT-CHAIN FATTY ACIDS METABOLISM REWIRING: A PROMOTION FOR NEUROENDOCRINE DIFFERENTIATION INDUCED HORMONE THERAPY RESISTANCE IN PROSTATE CANCER

Huan Xu

Journal of Urology

DOI

2024

动物磁定向行为与磁感应机制研究进展

高勇勇，徐焕，雷忻，黄求应

《生态学报》，Vol. 44, No. 24

下载原文

2024

Androgen receptor deficiency-induced TUG1 in suppressing ferroptosis to promote benign prostatic hyperplasia through the miR-188-3p/GPX4 signal pathway

Ming Zhan, Huan Xu, Guo-Peng Yu, Qi Chen, Rui-Feng Yang, Yan-Bo Chen, Jianchao Ge, Zhong Wang, Rui-Meng Yang, Bin Xu

Redox Biology

DOI

2024

Acetate utilization promotes hormone therapy resistance in prostate cancer through neuroendocrine differentiation.

Dajun Gao, Yanting Shen, Lingfan Xu, Yi Sun, Hailiang Hu, Bin Xu, Zhong Wang, Huan Xu

Drug resistance updates

DOI

2024

Low-dose polystyrene microplastics exposure impairs fertility in male mice with high-fat diet-induced obesity by affecting prostate function.

Dajun Gao, Caoxu Zhang, Huaqi Guo, Huan Xu, Hui Liu, Zhong Wang, Bin Xu, Wei Gang

Environmental Pollution

DOI

2023

堤坝白蚁习性规律及其生物防治技术研究进展

黄求应，李刚华，刘龙，高勇勇，徐焕，孙鹏东，贾豹，张峰，陈龙佳，李明伟，向亚红，雷朝亮

《中国水利》

2023

Circadian Rhythms of Locomotor Activity Mediated by Cryptochrome 2 and Period 1 Genes in the Termites Reticulitermes chinensis and Odontotermes formosanus

Yongyong Gao, Huan Xu, Bao Jia, Yutong Liu, Ali Hassan, Qiuying Huang

Insects

DOI

2022

ELK1-mediated YTHDF1 drives prostate cancer progression by facilitating the translation of Polo-like kinase 1 in an m6A dependent manner

Peizhang Li, Yuan-Ping Shi, Dajun Gao, Huan Xu, Yun Zou, Zhong Wang, Wenzhi Li

International Journal on Biological Sciences

DOI

2022

A prospective randomized controlled trial comparing the effect and safety of Piranha and VersaCut morcellation devices in transurethral holmium laser enucleation of the prostate

Yan-Bo Chen, Huan Xu, Dajun Gao, Meng Gu, Chong Liu, M. Zhan, Zhi-Kang Cai, Qi Chen, Zhong Wang

International Urology and Nephrology

DOI

2022

E2F transcription factor 2-activated DLEU2 contributes to prostate tumorigenesis by upregulating serum and glucocorticoid-induced protein kinase 1

Peizhang Li, Huan Xu, Liu Yang, Ming Zhan, Yuan-Ping Shi, Cao-xu Zhang, Dajun Gao, Meng Gu, Yan-Bo Chen, Zhong Wang

Cell Death and Disease

DOI

2022

Glycolytic potential enhanced by blockade of pyruvate influx into mitochondria sensitizes prostate cancer to detection and radiotherapy

Huan Xu, Jun-Yi Chen, Zhi Cao, Xi Chen, Caihong Huang, Jin Ji, Yalong Xu, Jun-Feng Jiang, Yue Wang, Guo-Wang Xu, Li-Na Zhou, Jingyi He, Xue-Dong Wei, J. Wu, Zhong Wang, S. Ren, Fu-Bo Wang

Cancer Biology and Medicine

DOI

2022

Reprogramming hormone-sensitive prostate cancer to a lethal neuroendocrine cancer lineage by mitochondrial pyruvate carrier (MPC)

Huan Xu, Zhixiao Liu, Dajun Gao, Peizhang Li, Yan-Ting Shen, Yi Sun, Lingfan Xu, Nan Song, Yue Wang, Ming Zhan, Xuecai Gao, Zhong Wang

Molecular Metabolism

DOI

2022

METTL3-Mediated m6A Modification of lncRNA MALAT1 Facilitates Prostate Cancer Growth by Activation of PI3K/AKT Signaling

Y. Mao, Wen-Feng Li, Yiming Weng, Bao Hua, Xin Gu, Chao Lu, Bin Xu, Huan Xu, Zhong Wang

Cell Transplantation

DOI

2022

MAFG-AS1 is a prognostic biomarker and facilitates prostate cancer progression

Peizhang Li, Yuan-Ping Shi, Miaomiao Guo, Huan Xu, Ming Zhan, Zhong Wang, Yan-Bo Chen

Frontiers in Oncology

DOI

2022

Interaction between ELAVL1 and M6A Regulators in Prostate Cancer

Zhonglin Cai, Huan Xu, G. Bai, Hanjing Hu, Di Wang, Hong-Jun Li, Zhong Wang

Social Science Research Network

DOI

2022

ELAVL1 promotes prostate cancer progression by interacting with other m6A regulators

Zhonglin Cai, Huan Xu, G. Bai, Hanjing Hu, Di Wang, Hongjun Li, Zhong Wang

Frontiers in Oncology

DOI

2021

Screening to Identify an Immune Landscape-Based Prognostic Predictor and Therapeutic Target for Prostate Cancer

Yan-Ting Shen, Huan Xu, Manmei Long, Miaomiao Guo, Peizhang Li, Ming Zhan, Zhong Wang

Frontiers in Oncology

DOI

2021

Fatty Acid Metabolism Reprogramming in Advanced Prostate Cancer

Huan Xu, Yan-Bo Chen, Meng Gu, Chong Liu, Qi Chen, Ming Zhan, Zhong Wang

Metabolites

DOI

2021

CCBE1 is a Prognostic Biomarker and Contributes to Prostate Cancer Cell Progression.

Peizhang Li, Huan Xu, Ming Zhan, Yan-Bo Chen, Da-Chao Zheng, Meng Gu, Zi-wei Wei, Yu-Cheng Tao, Qi Chen, Miaomiao Guo, Zhong Wang

DOI

2020

Hypoxia-preconditioned adipose-derived stem cells combined with scaffold promote urethral reconstruction by upregulation of angiogenesis and glycolysis

Xiang Wan, M. Xie, Huan Xu, Zi-wei Wei, Hai-Jun Yao, Zhong Wang, Da-Chao Zheng

Stem cell research & therapeutics

DOI

2019

Hypoxia-inducible factor 1α (HIF-1α) mediates the epithelial-mesenchymal transition in benign prostatic hyperplasia.

Yan-Bo Chen, Huan Xu, Qiling Shi, Meng Gu, Xiang Wan, Qi Chen, Zhong Wang

International Journal of Clinical and Experimental Pathology

2018

Benign prostatic hyperplasia surgical scoring (BPHSS): an novel scoring system for the perioperative outcomes of holmium laser enucleation of the prostate

Huan Xu, Zhi-Kang Cai, Yan-Bo Chen, Meng Gu, Qi Chen, Zhong Wang

Lasers in Medical Science

DOI

2018

Surgical Treatment for Benign Prostatic Hyperplasia: Holmium Laser Enucleation of the Prostate (HoLEP).

Huan Xu, Xiang Wan, Meng Gu, Yan-Bo Chen, Qiling Shi, Qi Chen, Zhong Wang

Journal of Visualized Experiments

DOI

2018

A Comparative study of two types of organ-sparing surgeries for early stage penile cancer: Wide local excision vs partial penectomy.

Xiang Wan, Da-Chao Zheng, Chong Liu, Huan Xu, M. Xie, Juan Zhou, Hai-Jun Yao, Zhong Wang

European Journal of Surgical Oncology

DOI

2018

Comparison of Vela and holmium laser enucleation of the prostate: a retrospective clinical trial with a 12-month follow-up

Meng Gu, Chong Liu, Yan-Bo Chen, Huan Xu, Shi Fu, Qi Chen, Zhong Wang

International Urology and Nephrology

DOI

2017

DNMT1 Regulates IL-6- and TGF-β1-Induced Epithelial Mesenchymal Transition in Prostate Epithelial Cells

Hui Xu, Yan-Bo Chen, Qi Chen, Huan Xu, Yanxia Wang, Jiao Yu, Juan Zhou, Zhong Wang, Bing Xu

European Journal of Histochemistry

DOI

2017

Lack of adiponectin and adiponectin receptor 1 contributes to benign prostatic hyperplasia

Shi Fu, Huan Xu, Meng Gu, Chong Liu, Xiang Wan, Yan-Bo Chen, Qi Chen, Juan Zhou, Zhong Wang

OncoTarget

DOI

2017

Surgical treatment of advanced penile cancer

Ke Zhang, Xiang Wan, Huan Xu, Wenzhi Li, Juan Zhou, Ming-Xi Xu, Hai-Jun Yao, Zhong Wang

Journal of Cancer Research and Clinical Oncology

DOI

2017

Evaluation of noise hazard during the holmium laser enucleation of prostate

Huan Xu, Yan-Bo Chen, Meng Gu, Qi Chen, Zhong Wang

BMC Urology

DOI

2017

[Role of adiponectin in prostate cancer: A preliminary study].

Shi Fu, Huan Xu, Chong Liu, Meng Gu, Qiong Wang, Juan Zhou, Zhong Wang

Zhonghua nan ke xue = National journal of andrology

2017

The function of oxytocin: a potential biomarker for prostate cancer diagnosis and promoter of prostate cancer

Huan Xu, Shi Fu, Qi Chen, Meng Gu, Juan Zhou, Chong Liu, Yan-Bo Chen, Zhong Wang

OncoTarget

DOI

2017

Adiponectin deficiency contributes to the development and progression of benign prostatic hyperplasia in obesity

Shi Fu, Huan Xu, Meng Gu, Chong Liu, Qiong Wang, Xiang Wan, Yan-Bo Chen, Qi Chen, Yu-Bing Peng, Zhi-Kang Cai, Juan Zhou, Zhong Wang

Scientific Reports

DOI

2017

["3+1" bladder function restoration combined with holmium laser enucleation of the prostate for benign prostatic hyperplasia with acontractile detrusor].

Xiang Wan, Chong Liu, Huan Xu, Meng Gu, Yan-Bo Chen, Yu-Bing Peng, Qi Chen, Zhi-Kang Cai, Zhong Wang

Zhonghua nan ke xue = National journal of andrology

2017

Oxytocin: its role in benign prostatic hyperplasia via the ERK pathway.

Huan Xu, Shi Fu, Yan-Bo Chen, Qi Chen, Meng Gu, Chong Liu, Zhi-Guang Qiao, Juan Zhou, Zhong Wang

Clinical science

DOI

2016

SPOCK1 promotes tumor growth and metastasis in human prostate cancer

Qi Chen, Yuanchun Yao, Huan Xu, Yan-Bo Chen, Meng Gu, Zhi-Kang Cai, Zhong Wang

Drug Design, Development and Therapy

DOI

2016

Precise Transurethral Enucleation of Prostate: New Surgery Treatment for Benign Prostate Hyperplasia

Huan Xu, Meng Gu, Qi Chen, Yan-Bo Chen, Zhi-Kang Cai, Zhong Wang

DOI

2016

Retrospective comparison of the modified and traditional holmium laser transurethral prostatectomy based on a 1-year follow-up

Meng Gu, Huan Xu, Yan-Bo Chen, Zhi-Kang Cai, Yu-Bing Peng, Qi Chen, Zhong Wang

2016

Smoking habits and benign prostatic hyperplasia

Huan Xu, Shi Fu, Yan-Bo Chen, Qi Chen, Meng Gu, Zhong Wang

Medicine

DOI

2016

Prostatic vascular damage induced by cigarette smoking as a risk factor for recovery after holmium laser enucleation of the prostate (HoLEP)

Huan Xu, Chong Liu, Meng Gu, Yan-Bo Chen, Zhi-Kang Cai, Qi Chen, Zhong Wang

OncoTarget

DOI

2016

Efficacy and safety of an improved technique of holmium laser enucleation of the prostate versus open prostatectomy in treating enlarged prostates combined with multiple bladder stones : one-year of followup

Huan Xu, Yan-Bo Chen, Meng Gu, Zhi-Kang Cai, Zhong Wang, Qi Chen

2016

[Modified morcellation procedure in holmium laser enucleation of the prostate].

Huan Xu, Meng Gu, Qi Chen, Yan-Bo Chen, Zhong Wang

Zhonghua nan ke xue = National journal of andrology

2016

Comparison of plasmakinetic enucleation of the prostate with holmium laser enucleation of the prostate in the treatment of benign prostate hyperplasia

Yan-Bo Chen, Huan Xu, Hui Xu, Meng Gu, Juan Zhou, Zhi-Kang Cai, Zhong Wang, Qi Chen

2016

Sulforaphane Ameliorates Bladder Dysfunction through Activation of the Nrf2-ARE Pathway in a Rat Model of Partial Bladder Outlet Obstruction

Chong Liu, Huan Xu, Shi Fu, Yan-Bo Chen, Qi Chen, Zhi-Kang Cai, Juan Zhou, Zhong Wang

Oxidative Medicine and Cellular Longevity

DOI

2015

Vela激光——能否胜任剜除治疗前列腺增生新领袖的角色？（附光盘）

Zhong Wang, Meng Gu, Qi Chen, Huan Xu

精选作品

期刊论文

Puerarin inhibits Benign prostatic hyperplasia through regulating HIF-1α-HIF-1β/ AKT1/AP-1.

基于卫星跟踪钳嘴鹳空间运动规律初报

不同磁场强度对白蚁运动行为和磁感应受体基因表达量的影响

社会性昆虫表型可塑性调控机制的研究进展

菲对泥鳅运动活性及焦虑、社交行为的胁迫影响

Fibroblasts promote the progression of benign prostatic hyperplasia through colony-stimulating factor 1 receptor-mediated RTK signaling in prostatic epithelial cells

Integrating spatial transcriptomics and single-cell RNA-sequencing reveals epithelial cell alterations in benign prostatic hyperplasia following finasteride treatment

Arctigenin inhibits high glucose-induced EMT and cell proliferation to alleviate benign prostatic hyperplasia companied with type 2 diabetes mellitus through MBOAT4/ acylated Ghrelin/GHS-R.

PD35-08 SHORT-CHAIN FATTY ACIDS METABOLISM REWIRING: A PROMOTION FOR NEUROENDOCRINE DIFFERENTIATION INDUCED HORMONE THERAPY RESISTANCE IN PROSTATE CANCER

动物磁定向行为与磁感应机制研究进展

Androgen receptor deficiency-induced TUG1 in suppressing ferroptosis to promote benign prostatic hyperplasia through the miR-188-3p/GPX4 signal pathway

Acetate utilization promotes hormone therapy resistance in prostate cancer through neuroendocrine differentiation.

Low-dose polystyrene microplastics exposure impairs fertility in male mice with high-fat diet-induced obesity by affecting prostate function.

堤坝白蚁习性规律及其生物防治技术研究进展

Circadian Rhythms of Locomotor Activity Mediated by Cryptochrome 2 and Period 1 Genes in the Termites Reticulitermes chinensis and Odontotermes formosanus

ELK1-mediated YTHDF1 drives prostate cancer progression by facilitating the translation of Polo-like kinase 1 in an m6A dependent manner

A prospective randomized controlled trial comparing the effect and safety of Piranha and VersaCut morcellation devices in transurethral holmium laser enucleation of the prostate

E2F transcription factor 2-activated DLEU2 contributes to prostate tumorigenesis by upregulating serum and glucocorticoid-induced protein kinase 1

Glycolytic potential enhanced by blockade of pyruvate influx into mitochondria sensitizes prostate cancer to detection and radiotherapy

Reprogramming hormone-sensitive prostate cancer to a lethal neuroendocrine cancer lineage by mitochondrial pyruvate carrier (MPC)

METTL3-Mediated m6A Modification of lncRNA MALAT1 Facilitates Prostate Cancer Growth by Activation of PI3K/AKT Signaling

MAFG-AS1 is a prognostic biomarker and facilitates prostate cancer progression

Interaction between ELAVL1 and M6A Regulators in Prostate Cancer

ELAVL1 promotes prostate cancer progression by interacting with other m6A regulators

Screening to Identify an Immune Landscape-Based Prognostic Predictor and Therapeutic Target for Prostate Cancer

Fatty Acid Metabolism Reprogramming in Advanced Prostate Cancer

CCBE1 is a Prognostic Biomarker and Contributes to Prostate Cancer Cell Progression.

Hypoxia-preconditioned adipose-derived stem cells combined with scaffold promote urethral reconstruction by upregulation of angiogenesis and glycolysis

Hypoxia-inducible factor 1α (HIF-1α) mediates the epithelial-mesenchymal transition in benign prostatic hyperplasia.

Benign prostatic hyperplasia surgical scoring (BPHSS): an novel scoring system for the perioperative outcomes of holmium laser enucleation of the prostate

Surgical Treatment for Benign Prostatic Hyperplasia: Holmium Laser Enucleation of the Prostate (HoLEP).

A Comparative study of two types of organ-sparing surgeries for early stage penile cancer: Wide local excision vs partial penectomy.

Comparison of Vela and holmium laser enucleation of the prostate: a retrospective clinical trial with a 12-month follow-up

DNMT1 Regulates IL-6- and TGF-β1-Induced Epithelial Mesenchymal Transition in Prostate Epithelial Cells

Lack of adiponectin and adiponectin receptor 1 contributes to benign prostatic hyperplasia

Surgical treatment of advanced penile cancer

Evaluation of noise hazard during the holmium laser enucleation of prostate

[Role of adiponectin in prostate cancer: A preliminary study].

The function of oxytocin: a potential biomarker for prostate cancer diagnosis and promoter of prostate cancer

Adiponectin deficiency contributes to the development and progression of benign prostatic hyperplasia in obesity

["3+1" bladder function restoration combined with holmium laser enucleation of the prostate for benign prostatic hyperplasia with acontractile detrusor].

Oxytocin: its role in benign prostatic hyperplasia via the ERK pathway.

SPOCK1 promotes tumor growth and metastasis in human prostate cancer

Precise Transurethral Enucleation of Prostate: New Surgery Treatment for Benign Prostate Hyperplasia

Retrospective comparison of the modified and traditional holmium laser transurethral prostatectomy based on a 1-year follow-up

Smoking habits and benign prostatic hyperplasia

Prostatic vascular damage induced by cigarette smoking as a risk factor for recovery after holmium laser enucleation of the prostate (HoLEP)

Efficacy and safety of an improved technique of holmium laser enucleation of the prostate versus open prostatectomy in treating enlarged prostates combined with multiple bladder stones : one-year of followup

[Modified morcellation procedure in holmium laser enucleation of the prostate].

Comparison of plasmakinetic enucleation of the prostate with holmium laser enucleation of the prostate in the treatment of benign prostate hyperplasia

Sulforaphane Ameliorates Bladder Dysfunction through Activation of the Nrf2-ARE Pathway in a Rat Model of Partial Bladder Outlet Obstruction

Vela激光——能否胜任剜除治疗前列腺增生新领袖的角色？（附光盘）