百晓学者学者目录

刘武昆

副教授、副研究员、博士生导师、教授、研究员，南京中医药大学

精选作品

期刊论文

2026

科研思维与实验技能融合的“医学细胞生物学”教学改革

徐忠仁，温振帆，刘武昆

《科技风》

2026

Discovery and development of the preclinical candidate (SH-1092), a potent third generation EGFR inhibitor for the treatment of NSCLC.

Ke-Jun Liu, Feiwan Zou, He Zhang, Qi Liu, Luwei Han, Jing-Song Ye, Xiao-Ping Zhang, Xiao-Meng Zhang, Yunlong Lu, Wukun Liu

Bioorganic chemistry (Print)

DOI

2026

Spatial Au + Mapping Reveals a Self‐Amplifying Anti‐Tumor Immunity Loop Driven by Au(I) Complexes

Zhongren Xu, Zhiyue Fan, Lin Lv, Wei Lü, Zhenfan Wen, Wukun Liu

Advanced Science

DOI

2026

Au(III) Complexes as Pyroptosis Inducers by Targeting Mitochondrial DNA for Tumor Immunity

Lin Lv, Jing Shi, Zhenfan Wen, Ying Sun, Zhaoran Wang, Qiong Chen, Wukun Liu

Angewandte Chemie

DOI

2026

Drug-Conjugated Tam-NHC-Gold(I) Complexes Overcome ESR1 Mutant Breast Cancer Resistance and Downregulate the RAMP3/CALCR Signaling Pathway

Yunlong Lu, Lijuan Liu, Zhenlin Liang, Wayne A. Schroder, Zhenfan Wen, Tianpeng Zheng, Ben Niu, Chunqi Xie, Haitao Zhang, Jian Min, Qianming Du, Wukun Liu

Journal of Medicinal Chemistry

DOI

2026

Gold(I)-Loaded Nanomedicine for Liver Cancer: A Closed-Loop Strategy Integrating Ferritinophagy-Driven Ferroptosis and Immunotherapy

Yejin Zhu, Li Y, Yuming Jiang, Zhiyue Fan, Wukun Liu

Journal of Medicinal Chemistry

DOI

2026

Inhibitors of Ectonucleotidase CD39 for Immunotherapy of Cancer and Infections─Recent Developments and Future Perspectives

Chunyang Bi, Florian Schwermer, Lu Tang, Christa Elisabeth Müller, Wukun Liu

Journal of Medicinal Chemistry

DOI

2026

Novel Dual-Pharmacophore TrxR Inhibitors Integrating Ferroptosis and Antitumor Immunity: A Closed-Loop Strategy for TIME Remodeling

Zhongren Xu, Zhibin Yang, Lin Lv, Jiaqi Yang, Wukun Liu

Journal of Medicinal Chemistry

DOI

2026

Drug Discovery Targeting Carbonic Anhydrase

Weina Zhong, Xueying Li, Wei Zhang, Wukun Liu

DOI

2025

以“顺铂的抗癌功能发现”为载体的药事管理专业药物化学课程思政实践

于小轩，刘武昆

《大学化学》

2025

A dinuclear gold(I) complex with bis(N-heterocyclic carbene) ligands potentiated immune responses against liver cancer via ROS-driven endoplasmic reticulum stress and ferroptosis

Qiuyue Lu, Min Shan, Jiaqi Yang, Zhongren Xu, Yueyue Lei, Wukun Liu

Chinese Chemical Letters

DOI

2025

Advances in combination therapy for the treatment of estrogen receptor positive breast cancer

Lijuan Liu, Zhihao Zhao, Feiwan Zou, Wukun Liu, Yunlong Lu

Chinese Chemical Letters

2025

Isoalantolactone induces AML pyroptosis and potentiates α-PD-1 efficacy by targeting selenoprotein TXNRD1

Xiaoxuan Yu, Yanyu Zhou, Shibo Sun, Lu Tang, Wan Zhang, Jianqiang Xu, Wukun Liu

Acta Pharmaceutica Sinica B

DOI

2025

Au–Mn Bond Formal Metathesis with Ar–F via Synergistic Bimetallic Activation

Siyu Xia, Weina Zhong, Tingrui Li, Zhongren Xu, Jie Han, Wukun Liu, Weipeng Li, Chengjian Zhu, Jin Xie

Journal of the American Chemical Society

DOI

2025

Glabridin‐Gold(I) Complex as a Novel Immunomodulatory Agent Targeting TrxR and MAPK Pathways for Synergistic Enhancement of Antitumor Immunity

Zhaoran Wang, Meiyu Wang, Qiong Chen, Mengshi Wang, Fuwei Li, Lin Lv, Zhenfan Wen, Zhongren Xu, Yixia Yang, Chunyang Bi, Wukun Liu

Advanced Science

DOI

2025

Au(III) Schiff base complexes as oxidoreductase inhibitors against carbapenem- and colistin-resistant Gram-negative bacteria via targeting redox active motifs

Xiuli Chen, Lin Lv, Jianqiang Xu, Jingxin Shi, Xi Chen, Guisha Zi, Yuxuan Wu, Shibo Sun, Yufan Pang, Qian Song, Ling Ma, Shuang Wei, Tonghui Ma, Wukun Liu

Redox Biology

DOI

2025

Evaluating indole‑gold(I) based complexes as potential anti lymphoma agents by disrupting the thioredoxin reductase/glutathione peroxidase axis

Sicong Wang, Min Shan, Zhongren Xu, Guizhi Jiang, Mengshi Wang, Yanyu Zhou, Xiao Yan Zhao, Kathryn Fay Tonissen, Wukun Liu, Giovanna Di Trapani

Journal of Inorganic Biochemistry

DOI

2025

Dual-Targeting TrxR-EGFR Alkynyl-Au(I) Gefitinib Complex Induces Ferroptosis in Gefitinib-Resistant Lung Cancer via Degradation of GPX4

Lingling Wang, Xiaoyan Ma, Ling De Zhou, Miao Luo, Yunlong Lu, Yawen Wang, Pengdou Zheng, Huiguo Liu, Xiansheng Liu, Wukun Liu, Shuang Wei

Journal of Medicinal Chemistry

DOI

2025

The antimicrobial activity of auranofin and other gold complexes

Xiuli Chen, Lin Lv, Shuang Wei, Wukun Liu

Future Medicinal Chemistry

DOI

2025

Targeting KAT6A/B as a New Therapeutic Strategy for Cancer Therapy

Tianpeng Zheng, Shanglong Wang, Wukun Liu, Yunlong Lu

Journal of Medicinal Chemistry

DOI

2025

Synthesis and discovery of simplified pleurotin analogs bearing tricyclic core as novel thioredoxin reductase inhibitors

Bin Huang, Zhongren Xu, Dezhong Liao, Yuxia Zhang, Mengze Ruan, Zhiyue Fan, Wukun Liu, Ya‐Qiu Long

European Journal of Medicinal Chemistry

DOI

2024

Metal complexes bearing EGFR‐inhibiting ligands as promising anticancer agents

Xiaoyan Ma, Zhao-Ran Wang, Yifei Li, Yawen Wang, Wukun Liu

Medicinal research reviews (Print)

DOI

2024

A terbium(III) complex-based time-resolved luminescent probe for selenocysteine as an inhibitor of selenoproteins.

Jie-Fang Chen, Furong Gao, Zhong-Ren Xu, Yuan-Hao Liu, Ming Hu, Chengyi Yuan, Yun-Hua Zhang, Wukun Liu, Xiaohui Wang

Chemical Communications

DOI

2024

Simultaneous Activation of Immunogenic Cell Death and cGAS-STING Pathway by Liver- and Mitochondria-Targeted Gold(I) Complexes for Chemoimmunotherapy of Hepatocellular Carcinoma.

Fuwei Li, Zhen-Fan Wen, Chuanxing Wu, Zhibin Yang, Zhao-Ran Wang, Wenjing Diao, Da-Hong Chen, Zhong-Ren Xu, Yunlong Lu, Wukun Liu

Journal of Medicinal Chemistry

DOI

2024

Recent Advances of Metal Complexes in the Treatment of Hepatocellular Carcinoma

Zhongren Xu, Yu Liu, Jiaqi Yang, Fuwei Li, Wukun Liu

Journal of Medicinal Chemistry

DOI

2024

Erlotinib-Gold(I) Complex Induces Leukemia Cell DC Differentiation and Remodels the Immunosuppressive Microenvironment

Xiaoxuan Yu, Yanyu Zhou, Xiaoyan Ma, Wan Zhang, Fuwei Li, Fengyu Jiang, Yawen Wang, Qin Zhang, Wukun Liu

Journal of Medicinal Chemistry

DOI

2024

Gold(I) complexes bearing EGFR-inhibiting ligands as anti-HCC agents through dual targeting of EGFR and TrxR

Yawen Wang, Xiaoyan Ma, Xuejie Chen, Zhenfan Wen, Chunyang Bi, Zhongren Xu, Wukun Liu

European Journal of Medicinal Chemistry

DOI

2024

Recent advances of Schiff base metal complexes as potential anticancer agents

Lin Li Lv, Tianpeng Zheng, Lu Tang, Zhaoran Wang, Wukun Liu

Coordination Chemistry Reviews

DOI

2024

More than just DNA damage: Pt(ΙΙ)-NHC complexes derived from 4,5-diarylimidazoles augment immunogenic cell death

Lu Tang, Xingyu Chang, Jing Shi, Zhenfan Wen, Chunyang Bi, Wukun Liu

European Journal of Medicinal Chemistry

DOI

2024

Research progress of natural product-conjugated platinum and gold complexes as potential antitumor agents

Meiyu Wang, Fuwei Li, Zhaoran Wang, Lin Li Lv, Wukun Liu

European Journal of Medicinal Chemistry

DOI

2024

Discovery of non-antiproliferative selective estrogen receptor degraders (SERDs) based on scaffold optimization of elacestrant

Yunlong Lu, Zhihao Zhao, Shanglong Wang, Tianpeng Zheng, Xuejie Chen, Lijuan Liu, Lijuan Liu, Yuqing Zhu, Wukun Liu

European Journal of Medicinal Chemistry

DOI

2024

Discovery of novel quinoline scaffold selective estrogen receptor degraders (SERDs) for treatment of ER positive breast cancer with enhanced antiproliferative bioactivity through immunogenic cell death (ICD) effects

Yunlong Lu, Zhenlin Liang, Lijuan Liu, Lijuan Liu, Yanyu Zhou, Chao Liu, Chao Liu, Zhihao Zhao, Tianpeng Zheng, Qianming Du, Wukun Liu

European Journal of Medicinal Chemistry

DOI

2024

Synthesis, characterization and anti-ovarian cancer activities of novel biphenyl-NHC-gold(I) complexes

Meiyu Wang, Yifei Li, Guizhi Jiang, Fuwei Li, Yunlong Lu, Wukun Liu

Journal of Organometallic Chemistry

DOI

2024

Drug conjugates for the treatment of lung cancer: from drug discovery to clinical practice

Ling Zhou, Yunlong Lu, Wei Liu, Shanglong Wang, Lingling Wang, Pengdou Zheng, Guisha Zi, Huiguo Liu, Wukun Liu, Shuang Wei

Experimental Hematology and Oncology

DOI

2023

NHC-gold(I)-alkyne complexes induced hepatocellular carcinoma cell death through bioorthogonal activation by palladium complex in living system

Yunlong Lu, Yuan-Hao Liu, Zhenlin Liang, Xiaoyan Ma, Lijuan Liu, Zhen-Fan Wen, Iogann Tolbatov, A. Marrone, Wukun Liu

Chinese Chemical Letters

DOI

2023

Gold(I) selenium N-heterocyclic carbene complexes as potent antibacterial agents against multidrug-resistant gram-negative bacteria via inhibiting thioredoxin reductase

Xiuli Chen, Shi-Bo Sun, Sheng Huang, Han Yang, Qing Ye, Lin Lv, Yanshan Liang, Jinjun Shan, Jian-Qiang Xu, Wukun Liu, Tong-Hui Ma

Redox Biology

DOI

2023

Research Progress on Bioactive Metal Complexes against ER-Positive Advanced Breast Cancer.

Zhenlin Liang, Lijuan Liu, Yanyu Zhou, Wukun Liu, Yunlong Lu

Journal of Medicinal Chemistry

DOI

2023

Design, synthesis and biological evaluation of fluorinated selective estrogen receptor degraders (FSERDs) --- A promising strategy for advanced ER positive breast cancer.

Yunlong Lu, Chao Liu, Xin Wang, Lijuan Liu, Zhi-Hao Zhao, Zhenlin Liang, Yuan-Hao Liu, Zhen-Fan Wen, Qian-Ming Du, Wukun Liu

European journal of medicinal chemistry

DOI

2023

SERD-NHC-Au(I) complexes for dual targeting ER and TrxR to induce ICD in breast cancer.

Yunlong Lu, Xi Sheng, Chao Liu, Zhenlin Liang, Xin Wang, Lijuan Liu, Zhen-Fan Wen, Zhibin Yang, Qian-Ming Du, Wukun Liu

Pharmacological Research

DOI

2023

NSAID-Au(I) Complexes Induce ROS-Driven DAMPs and Interpose Inflammation to Stimulate the Immune Response against Ovarian Cancer.

Zhong-Ren Xu, Qiuyue Lu, Shan Min, Guizhi Jiang, Yuan-Hao Liu, Zhibin Yang, Yunlong Lu, Wukun Liu

Journal of Medicinal Chemistry

DOI

2023

Tumor-Targeting NHC-Au(I) Complex Induces Immunogenic Cell Death in Hepatocellular Carcinoma.

Zhibin Yang, Mian-Li Bian, Lin Lv, Xingyu Chang, Zhen-Fan Wen, Fuwei Li, Yunlong Lu, Wukun Liu

Journal of Medicinal Chemistry

DOI

2022

Mecheliolide elicits ROS-mediated ERS driven immunogenic cell death in hepatocellular carcinoma

Zhong-Ren Xu, Jian-Qiang Xu, Shi-Bo Sun, Wei Lin, Yongming Li, Qiuyue Lu, Fu‐Jian Li, Zhibin Yang, Yunlong Lu, Wukun Liu

Redox Biology

DOI

2022

Biotin-Targeted Au(I) Radiosensitizer for Cancer Synergistic Therapy by Intervening with Redox Homeostasis and Inducing Ferroptosis.

Zhibin Yang, Sheng Huang, Yu Liu, Xingyu Chang, Yanshan Liang, Xi Li, Zhong-Ren Xu, Shi-Yu Wang, Yunlong Lu, Yuan Liu, Wukun Liu

Journal of Medicinal Chemistry

DOI

2022

Repurposing of the gold drug auranofin and a review of its derivatives as antibacterial therapeutics.

Yuan-Hao Liu, Yunlong Lu, Zhong-Ren Xu, Xiaoyan Ma, Xiuli Chen, Wukun Liu

Drug Discovery Today

DOI

2022

Induction of Immunogenic Cell Death by Novel Platinum-Based Anticancer Agents.

Xingyu Chang, Mian-Li Bian, Lijuan Liu, Jiaqi Yang, Zhibin Yang, Zhao-Ran Wang, Yunlong Lu, Wukun Liu

Pharmacological Research

DOI

2022

Heteroleptic Gold(I)-bisNHC complex with excellent activity in vitro, ex vivo and in vivo against endometrial cancer.

Qimeng Xiao, Yuan-Hao Liu, Gui-Ji Jiang, Yuan Liu, Yan-fei Huang, Wukun Liu, Zhen-Bo Zhang

European journal of medicinal chemistry

DOI

2022

Recent development of gold(I) and gold(III) complexes as therapeutic agents for cancer diseases.

Yunlong Lu, Xiaoyan Ma, Xingyu Chang, Zhenlin Liang, Lin Lv, Shan Min, Qiuyue Lu, Zhen-Fan Wen, R. Gust, Wukun Liu

Chemical Society Reviews

DOI

2022

Novel phosphanegold(I) thiolate complexes suppress de novo lipid synthesis in human lung cancer.

Miao Luo, Xiaoyan Ma, Wei-Ling Jiang, Jun Zhang, Wukun Liu, Shuang Wei, Hui-Guo Liu

European journal of medicinal chemistry

DOI

2022

Pt(II)-NHC Complex Induces ROS-ERS-Related DAMP Balance to Harness Immunogenic Cell Death in Hepatocellular Carcinoma.

Mian-Li Bian, Rong Fan, Zhibin Yang, Ya-Nan Chen, Zhong-Ren Xu, Yunlong Lu, Wukun Liu

Journal of Medicinal Chemistry

DOI

2021

An overview of anticancer platinum N-heterocyclic carbene complexes

Sai Zhao, Zhibin Yang, Gui-Ji Jiang, Sheng Huang, Mian-Li Bian, Yunlong Lu, Wukun Liu

Coordination chemistry reviews

DOI

2021

Synthesis and in vitro anticancer activities of selenium N‐heterocyclic carbene compounds

Sheng Huang, Xin-Yu Sheng, Mian-Li Bian, Zhibin Yang, Yunlong Lu, Wukun Liu

Chemical Biology and Drug Design

DOI

2021

Editorial: Frontiers in Chemistry-Rising Stars: Asia

Lei Guo, J. Mohanty, Wukun Liu, T. Yonar, Hong-Yan Sun, T. Minami, Jafar Soleymani, B. Moosa, Qian-Xiong Zhou

Frontiers in Chemistry

DOI

2021

Editorial: The Golden Future in Medicinal Chemistry: Perspectives and Resources From Old and New Gold-Based Drug Candidates

L. Massai, S. Grgurić‐Šipka, Wukun Liu, B. Bertrand, A. Pratesi

Frontiers in Chemistry

DOI

2020

金属氮杂环卡宾配合物的抗肿瘤活性研究进展

樊荣，杨志斌，卞勉励，刘武昆

《化学通报(中英文)》

DOI

2020

Halo and Pseudohalo Gold(I)-NHC Complexes Derived from 4,5-Diarylimidazoles with Excellent in Vitro and in Vivo Anticancer Activity Against HCC.

Mian-Li Bian, Rong Fan, Gui-Ji Jiang, Ying-Xia Wang, Yunlong Lu, Wukun Liu

Journal of Medicinal Chemistry

DOI

2020

A Gold(I) Complex Containing an Oleanolic Acid Derivative as a Potential Anti-ovarian Cancer Agent via Inhibiting TrxR and Activating ROS-mediated ERS.

Mian-Li Bian, Ying Sun, Yuan-Hao Liu, Zhong-Ren Xu, Rong Fan, Zi-Wen Liu, Wukun Liu

Chemistry

DOI

2020

Selective Estrogen Receptor Degraders (SERDs): A Promising Strategy for Estrogen Receptor Positive Endocrine-Resistant Breast Cancer.

Yunlong Lu, Wukun Liu

Journal of Medicinal Chemistry

DOI

2020

Synthesis and biological evaluation of gold(III) Schiff base complexes for the treatment of hepatocellular carcinoma through attenuating TrxR activity.

Mian-Li Bian, Xin Wang, Ying Sun, Wukun Liu

European journal of medicinal chemistry

DOI

2020

Discovery of Potential Flavonoid Inhibitors Against COVID-19 3CL Proteinase Based on Virtual Screening Strategy

Zhong-Ren Xu, Lixiang Yang, Xinghao Zhang, Qi-Ling Zhang, Zhibin Yang, Yuan-Hao Liu, Shuang Wei, Wukun Liu

Frontiers in Molecular Biosciences

DOI

2020

Gold(I) complexes containing pentacyclic triterpene derivatives as potential anti-ovarian cancer agents via inhibiting TrxR and activating ROS-mediated ERS

Wukun Liu

DOI

2020

A novel fermented Yi traditional medicine efficiently suppresses the replication of SARS-CoV-2 in vitro

S. Fang, Ben-Hong Xu, Xiang-Rong Song, Wukun Liu, Yong-Mei Xie, Xi-Fei Yang

bioRxiv

DOI

2020

Pt(II) and Au(III) complexes containing Schiff-base ligands: A promising source for antitumor treatment.

Ying Sun, Yunlong Lu, Mian-Li Bian, Zhibin Yang, Xiao-Yan Ma, Wukun Liu

European journal of medicinal chemistry

DOI

2020

Advances in alkynyl gold complexes for use as potential anticancer agents

Zhibin Yang, Gui-Ji Jiang, Zhong-Ren Xu, Sai Zhao, Wukun Liu

Coordination chemistry reviews

DOI

2020

Design and Synthesis of Tetrazole- and Pyridine-Containing Itraconazole Analogs as Potent Angiogenesis Inhibitors.

Ying-Jun Li, K. Pasunooti, Han-Jing Peng, Ruo-Jing Li, Wei Q. Shi, Wukun Liu, Zhiqiang Cheng, Sarah A. Head, Jun O. Liu

ACS Medicinal Chemistry Letters

DOI

2019

Methods for Brominations at Benzylic Positions

Sai Zhao, Wukun Liu

Current organic chemistry

DOI

2019

A new rhodium(I) NHC complex inhibits TrxR: In vitro cytotoxicity and in vivo hepatocellular carcinoma suppression.

Rong Fan, Mian-Li Bian, Li-Hong Hu, Wukun Liu

European journal of medicinal chemistry

DOI

2019

Discovery of a potent GLUT inhibitor using rapafucin 3D microarrays

Zu-Feng Guo, Zhiqiang Cheng, Jingxin Wang, Wukun Liu, Han-Jing Peng, Yuefan Wang, A. V. Subbarao, Ruo-Jing Li, X. Ying, P. Korangath, Maria Liberti, Ying-Jun Li, Yong-Mei Xie, Sam Y. Hong, C. Schiene-Fischer, G. Fischer, J. Locasale, S. Sukumar, Heng Zhu, Jun O. Liu

Angewandte Chemie

DOI

2019

Targeting the Thioredoxin System as a Strategy for Cancer Therapy.

Mian-Li Bian, Rong Fan, Sai Zhao, Wukun Liu

Journal of Medicinal Chemistry

DOI

2018

Novel Tetrazole-Containing Analogues of Itraconazole as Potent Antiangiogenic Agents with Reduced Cytochrome P450 3A4 Inhibition.

Ying-Jun Li, K. Pasunooti, Ruo-Jing Li, Wukun Liu, Sarah A. Head, Wei Q. Shi, Jun O. Liu

Journal of Medicinal Chemistry

DOI

2018

Rapamycin-inspired macrocycles with new target specificity

Zu-Feng Guo, Sam Y. Hong, Jingxin Wang, Shahid Rehan, Wukun Liu, Han-Jing Peng, Manisha Das, Wei Li, S. Bhat, Brandon Peiffer, B. Ullman, C. Tse, Zlatina Tarmakova, C. Schiene-Fischer, G. Fischer, I. Coe, Ville O. Paavilainen, Zhao-Li Sun, Jun O. Liu

Nature Chemistry

DOI

2016

Update on metal N-heterocyclic carbene complexes as potential anti-tumor metallodrugs

Wukun Liu, R. Gust

DOI

2014

Design, Synthesis and Biological Evaluation of 5-Amino-1H-pyrazole-4- carboxamide Derivatives as Potential Antitumor Agents

Bao-Wei Yang, Wukun Liu, Yi-Cheng Mei, Dan-Dan Huang, Hai Qian, Wenlong Huang, R. Gust

DOI

2014

Synthesis, Characterization, and in vitro Antiproliferative Activity of [Salophene]platinum(II) Complexes

Maria T. Proetto, Wukun Liu, A. Molchanov, W. Sheldrick, A. Hagenbach, U. Abram, R. Gust

ChemMedChem

DOI

2013

Metal N-heterocyclic carbene complexes as potential antitumor metallodrugs.

Wukun Liu, R. Gust

Chemical Society Reviews

DOI

2012

Design and synthesis of thiourea derivatives containing a benzo[5,6]cyclohepta[1,2-b]pyridine moiety as potential antitumor and anti-inflammatory agents.

Wukun Liu, Jinpei Zhou, Tong-Tian Zhang, Haiyang Zhu, Hai Qian, Hui-Bin Zhang, Wenlong Huang, R. Gust

Bioorganic & Medicinal Chemistry Letters

DOI

2012

Synthesis, characterization and in vitro antitumour activity of a series of novel platinum(II) complexes bearing Schiff base ligands.

Maria T. Proetto, Wukun Liu, A. Hagenbach, U. Abram, R. Gust

European journal of medicinal chemistry

DOI

2012

Synthesis, characterization, and biological studies of silver and gold N-heterocyclic carbene complexes derived from 4,5-diarylimidazoles

Wukun Liu

2012

Synthesis, Antitumor, and Antibacterial Activity of Bis[4,5‐diarylimidazol‐2‐ylidene]methane Derivatives

Wukun Liu, Xiaohua Chen, R. Gust

Archiv der Pharmazie

DOI

2012

Synthesis and in vitro antitumor activity of novel scopoletin derivatives.

Wukun Liu, J. Hua, Jinpei Zhou, Hui-Bin Zhang, Haiyang Zhu, Yan-Hua Cheng, R. Gust

Bioorganic & Medicinal Chemistry Letters

DOI

2012

Synthesis and biological evaluation of cyanoguanidine derivatives of loratadine.

Wukun Liu, Jinpei Zhou, Tong-Tian Zhang, Hui-Bin Zhang, Haiyang Zhu, Yan-Hua Cheng, R. Gust

Bioorganic & Medicinal Chemistry Letters

DOI

2012

Synthesis, characterization, and in vitro studies of bis[1,3-diethyl-4,5-diarylimidazol-2-ylidene]gold(I/III) complexes.

Wukun Liu, Kerstin Bensdorf, Maria T. Proetto, A. Hagenbach, U. Abram, R. Gust

Journal of Medicinal Chemistry

DOI

2012

Design, synthesis and antiproliferative activity of 2-acetamidothiazole-5-carboxamide derivatives.

Wukun Liu, Jinpei Zhou, Yu Zheng, F. Qi, Hui-Bin Zhang, Hai Qian, Jing Wang, Yan-Hua Cheng, R. Gust

Medicinal chemistry

DOI

2012

CCDC 875153: Experimental Crystal Structure Determination

Wukun Liu, Kerstin Bensdorf, Maria T. Proetto, U. Abram, A. Hagenbach, R. Gus

DOI

2011

Synthesis and Biological Evaluation of Licofelone Derivatives as Anticancer and Anti-inflammatory Agents

Wukun Liu, Jinpei Zhou, Hui-Bin Zhang, Hai Qian, Ji-hong Yin, Kerstin Bensdorf, R. Gust

DOI

2011

Investigations on cytotoxicity and anti-inflammatory potency of licofelone derivatives.

Wukun Liu, Jinpei Zhou, Kerstin Bensdorf, Hui-Bin Zhang, Hao-Ran Liu, Yu-Bin Wang, Hai Qian, Yan-Chun Zhang, A. Wellner, Gerhard Rubner, Wenlong Huang, Can-Cheng Guo, R. Gust

European journal of medicinal chemistry

DOI

2011

Licofelone–Nitric Oxide Donors as Anticancer Agents

Wukun Liu, Jinpei Zhou, Ying-Lin Liu, Hao-Ran Liu, Kerstin Bensdorf, Can-Cheng Guo, R. Gust

Archiv der Pharmazie

DOI

2011

NHC gold halide complexes derived from 4,5-diarylimidazoles: synthesis, structural analysis, and pharmacological investigations as potential antitumor agents.

Wukun Liu, Kerstin Bensdorf, Maria T. Proetto, U. Abram, A. Hagenbach, R. Gust

Journal of Medicinal Chemistry

DOI

2011

Synthesis and Biological Activities of 2‐Amino‐thiazole‐5‐carboxylic Acid Phenylamide Derivatives

Wukun Liu, Jinpei Zhou, F. Qi, Kerstin Bensdorf, Zhi-Yu Li, Hui-Bin Zhang, Hai Qian, Wenlong Huang, Xue-Ting Cai, P. Cao, A. Wellner, R. Gust

Archiv der Pharmazie

DOI

2011

Synthesis and biological studies of silver N-heterocyclic carbene complexes derived from 4,5-diarylimidazole.

Wukun Liu, Kerstin Bensdorf, A. Hagenbach, U. Abram, Ben Niu, Aruljothi Mariappan, R. Gust

European journal of medicinal chemistry

DOI

2010

Selective synthesis and biological activity of triazine-porphyrins as potential anti-cancer agents

Shen Xiao, Chao-Zhou Liu, Wukun Liu, Wenwei Xie, Wei-Ying Lin, G. Jiang, Can-Cheng Guo

DOI

2009

非甾体抗炎药Licofelone的合成研究

魏丽娟，周金培，刘武昆，王玉斌，黄文龙

《药学进展》

2009

Porphyrins containing nitric oxide donors: Synthesis and cancer cell-oriented NO release.

Wukun Liu, Chao-Zhou Liu, Changjun Gong, Weiying Lin, Can-Cheng Guo

Bioorganic & Medicinal Chemistry Letters

DOI

2007

非甾体抗炎药环氧化酶/5-脂氧化酶双重抑制剂的研究进展

刘武昆，周金培

《药学进展》

会议论文

2019

TrxR抑制剂铑(Ⅰ)氮杂环卡宾配合物的抗肝癌活性研究

樊荣，卞勉励，蒋桂枝，黄胜，孙颖，刘武昆

《第十一届全国化学生物学学术会议论文摘要（第一卷）》

DOI

2018

氮杂环卡宾金属配合物的设计、合成及生物活性研究

刘武昆，樊荣，卞勉励，蒋桂枝，黄胜，孙颖，Ronald Gust

《中国化学会第十四届全国生物无机化学学术会议》

DOI

2018

Design,synthesis,and biological studies of metal n-heterocyclic carbene complexes as potential antitumor metallodrugs

Wukun Liu, Rong Fan, Mianli Biao, Guizhi Jiang, Bajee Shaik, Sheng Huang, Yin Sun, Ronald Gust

《第11届世界华人药物化学研讨会（ISCMC 2018）》

书籍章节

2023

N-Heterocyclic carbene as privileged scaffold in medicinal inorganic chemistry

Yunlong Lu, Wan Zhang, Jing Cheng Shi, Yawen Wang, Wukun Liu

Elsevier eBooks

DOI

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