百晓学者学者目录

倪建泉

博士生导师、教授，清华大学

精选作品

期刊论文

2026

HP1γ promotes the progression of colorectal cancer through interaction with RBPJ of the Notch signaling pathway

Rui-Bao Zhu, Yi-Jia Xie, Yu-Ting Han, Bo Peng, Wen-Ting Wang, Xin-Yi Lu, Yu-Tong Li, De-Cai Mao, Jin Sun, De-Xin Chen, Qinyun Che, Li Zheng, Dong-Lin Li, Feng-Rui Hou, Meng-Lin Mo, Shi-Yao Gong, Yi-Zhi Dong, Rong-Zhi Fu, Qing-Fei Liu, Fang-Lin Sun, Zhi-Jie Chang, Jian‐Quan Ni, Ming-Yang Li

Cell Biology and Toxicology

DOI

2026

roX1 and roX2 lncRNAs promote heterochromatinization in intestinal stem cells and impair longevity

Kai-Le Li, Chen Wang, Yong-Hao Li, Bo Peng, Li Zheng, Qinyun Che, Xinyi Lu, Donglin Li, Yu-Tong Li, Hui-Min Wei, Jian-Feng Chang, Wenfei Wang, Mengmeng Liu, Xiangnan Li, Fangfang Jin, Kai Liu, Yabin Li, Li-Wei Liu, Mingyang Li, Jian‐Quan Ni, Ting Xie, Fang-Lin Sun

EMBO Reports

DOI

2022

模式动物果蝇的基因调控前沿技术

韩玉婷，许博文，李羽童，卢心怡，董习之，邱雨浩，车沁耘，朱芮葆，郑丽，李孝宸，司绪，倪建泉

《遗传》

2022

基因编辑技术在昆虫中的研究与应用

邱雨浩，贾豫，倪建泉，王冰，王桂荣

《昆虫学报》

2021

HP1c regulates development and gut homeostasis by suppressing Notch signaling through Su(H)

Jin Sun, Xia Wang, Rong‐Gang Xu, Decai Mao, Da Shen, Xin Wang, Yuhao Qiu, Yuting Han, Xinyi Lu, Yutong Li, Qinyun Che, Zheng Li, Ping Peng, Xuan Kang, Ruibao Zhu, Yu Jia, Yinyin Wang, Luping Liu, Zhijie Chang, Jun‐Yuan Ji, Zhao Wang, Qingfei Liu, Shao Li, Fang-Lin Sun, Jian‐Quan Ni

EMBO Reports

DOI

2020

SPATA4 improves aging‐induced metabolic dysfunction through promotion of preadipocyte differentiation and adipose tissue expansion

Zhongchi Li, Kang Xu, Sen Zhao, Yannan Guo, Huiling Chen, Jian‐Quan Ni, Qingfei Liu, Zhao Wang

Aging Cell

DOI

2020

Premature termination codon readthrough in Drosophila varies in a developmental and tissue-specific manner

Yanan Chen, Tianhui Sun, Zhuo Bi, Jian‐Quan Ni, José Carlos Pastor-Pareja, Babak Javid

Scientific Reports

DOI

2020

A high‐fat diet reverses metabolic disorders and premature aging by modulating insulin and IGF1 signaling in SIRT6 knockout mice

Zhongchi Li, Kang Xu, Yannan Guo, Lu Ping, Yuqi Gao, Ying Qiu, Jian‐Quan Ni, Qingfei Liu, Zhao Wang

Aging Cell

DOI

2019

The exocyst functions in niche cells to promote germline stem cell differentiation by directly controlling EGFR membrane trafficking

Ying Mao, Renjun Tu, Yan Huang, Decai Mao, Zhihao Yang, Pik Ki Lau, Jinhui Wang, Jian‐Quan Ni, Yusong Guo, Ting Xie

Development

DOI

2018

高效特异的CRISPR/dCas9转录激活系统——flySAM系统

贾豫，徐荣刚，孙锦，倪建泉

《遗传》

2018

果蝇研究技术与资源的开发

徐荣刚，王霞，王芳，孙锦，毛德才，乔欢欢，贾豫，朱芮葆，彭娉，刘鲁萍，倪建泉

《中国实验动物学报》

2018

Dimerization of p15RS mediated by a leucine zipper–like motif is critical for its inhibitory role on Wnt signaling

Xuanzi Fan, Juan Zhao, F. Ren, Yin-Yin Wang, Yarui Feng, Lidan Ding, Lin-Peng Zhao, Y. Shang, Jun Li, Jianquan Ni, B. Jia, Yu-Le Liu, Zhi-Jie Chang

Journal of Biological Chemistry

DOI

2018

An efficient and multiple target transgenic RNAi technique with low toxicity in Drosophila

Huanhuan Qiao, Fang Wang, Rong‐Gang Xu, Jin Sun, Ruibao Zhu, Decai Mao, Xingjie Ren, Xia Wang, Yu Jia, Ping Peng, Da Shen, Luping Liu, Zhijie Chang, Guirong Wang, Shao Li, Jun‐Yuan Ji, Qingfei Liu, Jian‐Quan Ni

Nature Communications

DOI

2016

果蝇新品系开发与种质资源保存

王霞，乔欢欢，潘丽霞，任兴杰，孙锦，徐荣刚，刘鲁萍，贺争鸣，倪建泉

《实验动物科学》

2016

DNA damage-induced Lok/CHK2 activation compromises germline stem cell self-renewal and lineage differentiation

Xing Ma, Yingying Han, Xiaoqing Song, Trieu Do, Zhihao Yang, Jian‐Quan Ni, Ting Xie

Development

DOI

2015

COP9-Hedgehog axis regulates the function of the germline stem cell progeny differentiation niche in the Drosophila ovary

Tinglin Lu, Su Wang, Yuan Gao, Ying Mao, Zhihao Yang, Luping Liu, Xiaoqing Song, Jian‐Quan Ni, Ting Xie

Development

DOI

2015

Twin Promotes the Maintenance and Differentiation of Germline Stem Cell Lineage through Modulation of Multiple Pathways

Ziwen Fu, Cuiyun Geng, Hui Wang, Zhihao Yang, Changjiang Weng, Hua Li, Lamei Deng, Luping Liu, Nan Liu, Jian‐Quan Ni, Ting Xie

Cell Reports

DOI

2015

Wnt signaling-mediated redox regulation maintains the germ line stem cell differentiation niche

Su Wang, Yuan Gao, Xiaoqing Song, Xing Ma, Xiujuan Zhu, Ying Mao, Zhihao Yang, Jian‐Quan Ni, Hua Li, Kathryn E Malanowski, Anoja G. Perera, Jungeun Park, Jeff Haug, Ting Xie

eLife

DOI

2015

Author response: Wnt signaling-mediated redox regulation maintains the germ line stem cell differentiation niche

Su Wang, Yuan Gao, Xiaoqing Song, Xing Ma, Xiujuan Zhu, Ying Mao, Zhihao Yang, Jian‐Quan Ni, Hua Li, Kathryn E Malanowski, Anoja G. Perera, Jungeun Park, Jeff Haug, Ting Xie

DOI

2014

Protein competition switches the function of COP9 from self-renewal to differentiation

Lei Pan, Su Wang, Tinglin Lu, Changjiang Weng, Xiaoqing Song, Joseph K. Park, Jin Sun, Zhihao Yang, Junjing Yu, Hong Tang, Dennis M. Mckearin, Daniel Chamovitz, Jian‐Quan Ni, Ting Xie

Nature

DOI

会议论文

2023

全基因组深度测序分析CRISPR/Cas9基因编辑导致果蝇基因组的意外突变

朱筱，伍颖，张星，李芝卉，张秋宇，胡彩姣，李长龙，陈振文，倪建泉，霍学云，杜小燕

《第十六届中国实验动物科学年会论文集》

DOI

研究方向

在动物个体水平上探究表观遗传因子与信号通路在干细胞行为中的交互作用

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