张旭敏｜复旦大学｜学者主页

2026

Integrative Quantitative Proteomics and N‐Glycoproteomics Reveal Age‐Processing of N‐Glycosylation in Caenorhabditis elegans

Xiaoyu Hu, Wei Xiang, Suideng Qin, Xumin Zhang, Zhi-Xin Tian

Proteomics

2026

An extensive forward genetic screen identifies the HWS-AGO1 axis as pivotal for target mimicry-mediated miRNA degradation in Arabidopsis.

Lin Yang, Mengyuan Liu, Mengwei Guo, You-Hong Fan, Youchao Wang, Ning Fang, Guiting Kang, Ning Li, Yixiao Fang, Jun Mei, Xumin Zhang, Jixi Li, Jinxiao Yang, Guo-Dong Ren

The Plant Journal

DOI

2026

Integrated Multi-omics Analysis Reveals that Hybrid Rice Reprograms Carbon Metabolism to Confer Drought Resistance.

Wei-Jia Ding, Jun-Guo Bi, Shoujun Chen, Zhen Wu, Zhi-Gang Liao, Lin Huang, Li-Jun Luo, Liang Chen, Xumin Zhang

Plant Communications

DOI

2026

The secreted elastase SjCE2b drives host skin penetration by Schistosoma japonicum

Bingkuan Zhu, Yi Shen, F. Luo, C. Su, Hong You, Xumin Zhang, Wei Hu

bioRxiv

DOI

2026

Gut microbial fucosidase unlocks the immunotherapy-enhancing potential of polysaccharides

Zhan-Ming Li, Chao-Yue Kong, Jia-Ting Huang, Hui-ling Chen, Bing Han, Xumin Zhang, Yu-Qin Mao, Li-Shun Wang

Microbiome

DOI

2026

SP3-PELSA: A rapid and sensitive approach for studying protein-ligand interaction with small-amount samples.

Jiaqin Chen, Guangxu Hu, Jie Song, Lin Huang, Xumin Zhang

Analytica Chimica Acta

DOI

2025

Quantitative Proteome and Phosphoproteome Profiling across Three Cell Lines Revealed Potential Proteins Relevant to Nasopharyngeal Carcinoma Metastasis.

Jie Song, Yi Shen, Zhen Wu, Lin Huang, Yun Deng, Wei Yu, Xiaoshen Wang, Xumin Zhang

Journal of Proteome Research

DOI

2024

102-Plex Approach for Accurate and Multiplexed Proteome Quantification.

Zhen Wu, Xi-Ru Huang, Lin Huang, Xumin Zhang

Analytical Chemistry

DOI

2024

Hydrophilic Peptide and Glycopeptide as Immobilized Sorbents for Glycosylation Analysis.

Zhaoliang Liu, Zhen Wu, Yufeng Zhou, Jun Xia, Wen-Qi Zhang, Song Gao, Shuwei Li, Zhaohui Lu, Xumin Zhang, Shuang Yang

Analytical Chemistry

DOI

2024

Annonaceous acetogenins mimic AA005 targets mitochondrial trifunctional enzyme alpha subunit to treat obesity in male mice

Bing Han, Zhan-Ming Li, Xu-Yun Zhao, K. Liang, Yu-Qin Mao, Shi-Long Zhang, Li-Ying Huang, Chao-Yue Kong, Xin Peng, Hui-ling Chen, Jia-Ting Huang, Zhao-xia Wu, Jin-Qing Yao, Pei-Ran Cai, Zheng-Yan Zhang, Xumin Zhang, Zhu-Jun Yao, Guoqiang Chen, Li-Shun Wang

Nature Communications

DOI

2024

Mass spectrometry analysis of intact protein N-glycosylation signatures of cells and sera in pancreatic adenocarcinomas

Mingming Xu, Zhaoliang Liu, Wenhua Hu, Ying Han, Zhen Wu, Sufeng Chen, Peng Xia, Jing Du, Xumin Zhang, Piliang Hao, Jun Xia, Shuang Yang

Journal of Zhejiang University SCIENCE B

DOI

2024

Aspirin‐Mediated Acetylation of SIRT1 Maintains Intestinal Immune Homeostasis

Li Xie, Chao-Qun Li, Chao Wang, Zhen Wu, Changchun Wang, Chunyu Chen, Xiaojian Chen, Dejian Zhou, Qiang Zhou, Ping Lu, C. Ding, Chen-Ying Liu, Jin-Zhong Lin, Xumin Zhang, Xiao-Fei Yu, Wei Yu

Advancement of science

DOI

2023

Hyperplexing Approaches for up to 45-Plex Quantitative Proteomic Analysis.

Zhanghua Wu, Wei Xiang, Lin Huang, Shuwei Li, Xumin Zhang

Analytical Chemistry

DOI

2023

Novel Approach to Enriching Glycosylated RNAs: Specific Capture of GlycoRNAs via Solid-Phase Chemistry.

Jiajia Li, Shuang-Fen Yue, Ziyuan Gao, P. H. Hopchev, Zhaoliang Liu, Guoqiang Xu, Zhen Wu, Xumin Zhang, Guo-Lin Zhang, Fuliang Qian, Jun-Hong Jiang, Shuang Yang

Analytical Chemistry

DOI

2023

Diagnostic Potential of Serum Glycome Analysis in Lung Cancer: A Glycopattern Study.

Wenhua Hu, Wei Ge, Peng Xia, Yan Chen, Jing Du, Guangxu Hu, Zhen Wu, Xumin Zhang, Chuanlai Yang, Jun-Hong Jiang, Shuang Yang, Jun Xia

Journal of Proteome Research

DOI

2023

Mass Spectrometric Analysis of Urinary N-Glycosylation Changes in Patients with Parkinson's Disease.

Mingming Xu, Hong Jin, Wei Ge, Ling-Bo Zhao, Zhaoliang Liu, Zeyu Guo, Zhen Wu, J. Chen, Cheng-Jie Mao, Xumin Zhang, Chun-Feng Liu, Shuang Yang

ACS Chemical Neuroscience

DOI

2023

Quantitative analysis of fucosylated glycoproteins by immobilized lectin-affinity fluorescent labeling

Ziyuan Gao, Sufeng Chen, Jing Du, Zhen Wu, Wei Ge, Song Gao, Zeyang Zhou, Xiaodong Yang, Yu-Fei Xing, M. Shi, Yunyun Hu, Wen Tang, Jun Xia, Xumin Zhang, Jun-Hong Jiang, Shuang Yang

RSC Advances

DOI

2023

Isolation of biofluids from tissues using a vacuum-assisted filtration biomedical device.

Arthur Z Yang, Yufeng Zhou, J. Hardy, Shiqing Fu, Yuan-jie Wang, Li Zhang, Zhen Wu, Xumin Zhang, Ci Wu, Jun-Feng Ma, Zeyang Zhou, Xiaodong Yang, Shuang Yang

Analytical Methods

DOI

2023

SCFRMF mediates degradation of the meiosis-specific recombinase DMC1

Wanyue Xu, Yue Yu, Juli Jing, Zhanghua Wu, Xumin Zhang, C. You, Hong Ma, G. Copenhaver, Yan He, Yingxiang Wang

Nature Communications

DOI

2023

Insight of novel biomarkers for papillary thyroid carcinoma through multiomics

W. Liu, Jun Zhu, Zhanghua Wu, Yong-Xiang Yin, Qiao Wu, Yiming Wu, Jiaojiao Zheng, Cong Wang, Hong-Yan Chen, T. J. Qazi, Jun Wu, Yuqing Zhang, Hou-Bao Liu, Jing-Min Yang, D. Lu, Xumin Zhang, Zhilong Ai

Frontiers in Oncology

DOI

2022

20℃和25℃条件下秀丽隐杆线虫衰老过程中磷酸化蛋白质组学的研究

李佳淇，吴真，张旭敏

《复旦学报(自然科学版)》

2022

重组LysargiNase蛋白酶的表达纯化及其在蛋白质组学层面的分析

岳柠柠，吴真，张旭敏

《复旦学报(自然科学版)》

2022

转录组和蛋白质组整合分析揭示组蛋白H2A去泛素化酶USP16的功能调控网络

华杰，吴真，张旭敏

《复旦学报(自然科学版)》

2022

TAG-TMTpro, a Hyperplexing Quantitative Approach for High-Throughput Proteomic Studies.

Zhanghua Wu, Yi Shen, Xumin Zhang

Analytical Chemistry

DOI

2022

One-day thermal regime extends the lifespan in Caenorhabditis elegans

Jichang Huang, Kai Wang, Meng-Qing Wang, Zhanghua Wu, Guang-Jie Xie, Yuling Peng, Yan Zhang, Xumin Zhang, Zhi-Yong Shao

Computational and Structural Biotechnology Journal

DOI

2022

TOX4 facilitates promoter-proximal pausing and C-terminal domain dephosphorylation of RNA polymerase II in human cells

Ziling Liu, Aiwei Wu, Zhen Wu, Talang Wang, Yi Pan, Bing Li, Xumin Zhang, Min Yu

Communications Biology

DOI

2022

Mass Spectrometry-Based Analysis of Serum N-Glycosylation Changes in Patients with Parkinson's Disease.

Mingming Xu, Hong Jin, Zhen Wu, Ying Han, Jing Chen, C. Mao, P. Hao, Xumin Zhang, Chun-Feng Liu, Shuang Yang

ACS Chemical Neuroscience

DOI

2022

Multi-Omics Analysis in β-Thalassemia Using an HBB Gene-Knockout Human Erythroid Progenitor Cell Model

Guoqiang Zhou, Hao-Kun Zhang, A. Lin, Zhanghua Wu, Tingxuan Li, Xumin Zhang, Hong-Yan Chen, Da-Ru Lu

International Journal of Molecular Sciences

DOI

2021

Aberrant Fucosylation of Saliva Glycoprotein Defining Lung Adenocarcinomas Malignancy

Ziyuan Gao, Zhen Wu, Ying Han, Xumin Zhang, P. Hao, Mingming Xu, Shangyu Huang, Shuwei Li, Jun Xia, Jun-Hong Jiang, Shuang Yang

bioRxiv

DOI

2021

Basic pH reversed-phase liquid chromatography (bRPLC) in combination with tip-based strong cation exchange (SCX-Tip), ReST, an efficient approach for large-scale cross-linked peptide analysis.

Zhen Wu, Jiaqi Li, Lin Huang, Xumin Zhang

Analytica Chimica Acta

DOI

2021

TOX4 Promotes Promoter Proximal Pause of RNA Polymerase Ii by Facilitating the Recruitment of DSIF and NELF

Zi-Ling Liu, Aiwei Wu, Zhen Wu, Talang Wang, Xumin Zhang, Ming Yu

DOI

2020

Author response: A muscle-epidermis-glia signaling axis sustains synaptic specificity during allometric growth in Caenorhabditis elegans

Jiale Fan, Tingting Ji, Kai Wang, Jichang Huang, Meng-Qing Wang, Laura Manning, Xiaohua Dong, Yan-Jun Shi, Xumin Zhang, Zhi-Yong Shao, D. Colón-Ramos

DOI

2020

Tyrosine-EDC Conjugation, an Undesirable Side Effect of the EDC-Catalyzed Carboxyl Labeling Approach.

Qingqing Li, Yang Zhang, Zhanghua Wu, Jingnan Huang, Ningning Yue, Lin Huang, Xumin Zhang

Analytical Chemistry

DOI

2020

Formaldehyde Derivatization, an Unexpected Side Reaction During Filter-Aided Sample Preparation.

Lang-Lang Tang, Zhanghua Wu, Jie Wang, Xumin Zhang

Analytical Chemistry

DOI

2020

Basic Strong Cation Exchange Chromatography, BaSCX, a Highly Efficient Approach for C-Terminomic Studies Using LysargiNase Digestion.

Qingqing Li, Yang Zhang, Jingnan Huang, Zhanghua Wu, Lang-Lang Tang, Lin Huang, Xumin Zhang

Analytical Chemistry

DOI

2020

A muscle-epidermis-glia signaling axis sustains synaptic specificity during allometric growth in Caenorhabditis elegans

Jiale Fan, Tingting Ji, Kai Wang, Jichang Huang, Meng-Qing Wang, Laura Manning, Xiaohua Dong, Yan-Jun Shi, Xumin Zhang, Zhi-Yong Shao, D. Colón-Ramos

eLife

DOI

2020

Global Quantitative Proteomics Studies Revealed Tissue-Preferential Expression and Phosphorylation of Regulatory Proteins in Arabidopsis

Jia-Nan Lu, Ying Fu, Mengyu Li, Shuang-Shuang Wang, Jing-Ya Wang, Qi Yang, Juanying Ye, Xumin Zhang, Hong Ma, F. Chang

International Journal of Molecular Sciences

DOI

2020

Short-Term Mild Temperature-Stress-Induced Alterations in the C. elegans Phosphoproteome

Jichang Huang, Zhanghua Wu, Xumin Zhang

International Journal of Molecular Sciences

DOI

2020

Phosphorylation of Msx1 promotes cell proliferation through the Fgf9/18-MAPK signaling pathway during embryonic limb development

Yenan Yang, Xiaoli Zhu, Xiang Jia, Wanwan Hou, Guoqiang Zhou, Zhangjing Ma, Bin Yu, Y. Pi, Xumin Zhang, Jingqiang Wang, Gang Wang

Nucleic Acids Research

DOI

2020

Msx1 cooperates with Runx1 for inhibiting myoblast differentiation.

Guoqiang Zhou, Yenan Yang, Xumin Zhang, Jingqiang Wang

Protein Expression and Purification

DOI

2019

基于质谱的蛋白质N末端乙酰化程度定量方法的研究

王洁，张旭敏

《基因组学与应用生物学》

DOI

2019

ADAMTS-family protease MIG-17 regulates synaptic allometry by modifying the extracellular matrix and modulating glia morphology during growth

Tingting Ji, Kai Wang, Jiale Fan, Jichang Huang, Meng-Qing Wang, Xiaohua Dong, Yan-Jun Shi, Laura Manning, Xumin Zhang, Zhi-Yong Shao, D. Colón-Ramos

bioRxiv

DOI

2019

Ubiquitylome study identifies increased histone 2A ubiquitylation as an evolutionarily conserved aging biomarker

Lu Yang, Zai-Jun Ma, Han Wang, Kong-Yan Niu, Ye Cao, Le Sun, Yang Geng, Bosen Yang, F. Gao, Zuo-Long Chen, Zhen Wu, Qingqing Li, Yong Shen, Xumin Zhang, Hong Jiang, Ye-Lin Chen, Rui Liu, Nan Liu, Yao-Yang Zhang

Nature Communications

DOI

2018

蛋白质组学样品消化条件的优化

黄竞男，张旭敏

《基因组学与应用生物学》

2018

Enzyme and Chemical Assisted N-Terminal Blocked Peptides Analysis, ENCHANT, as a Selective Proteomics Approach Complementary to Conventional Shotgun Approach.

Jingnan Huang, Jie Wang, Qingqing Li, Yang Zhang, Xumin Zhang

Journal of Proteome Research

DOI

2018

Revealing A-Raf functions through its interactome.

Xin-Yi Zhang, Hui Guo, B. Han, Xumin Zhang, Ying Huang, Yang Yang, Ying Liu, Xiao-Xi Guo, Qian Hao, Su An, Tian-Rui Xu

Biochimica et Biophysica Acta - Proteins and Proteomics

DOI

2018

Lys-C/Arg-C, a More Specific and Efficient Digestion Approach for Proteomics Studies.

Zhen Wu, Jichang Huang, Jingnan Huang, Qingqing Li, Xumin Zhang

Analytical Chemistry

DOI

2018

An Approach to Incorporate Multi‐Enzyme Digestion into C‐TAILS for C‐Terminomics Studies

Yang Zhang, Qingqing Li, Jingnan Huang, Zhen Wu, Jichang Huang, Lin Huang, Yanhong Li, Juanying Ye, Xumin Zhang

Proteomics

DOI

2018

Reversible Lysine Derivatization Enabling Improved Arg-C Digestion, a Highly Specific Arg-C Digestion Using Trypsin.

Zhen Wu, Jichang Huang, Jia-Nan Lu, Xumin Zhang

Analytical Chemistry

DOI

2018

Quantitative phosphoproteomics reveals GTBP-1 regulating C.elegans lifespan at different environmental temperatures.

Jichang Huang, Zhen Wu, Jie Wang, Xumin Zhang

Biochemical and Biophysical Research Communications - BBRC

DOI

2017

末端蛋白质组学研究进展

黄竞男，李青青，黄继昌，王洁，周国强，叶娟英，张旭敏

《生命的化学》

DOI

2017

Comparative Analysis of Proteome-Wide Lysine Acetylation in Juvenile and Adult Schistosoma japonicum

Qing Li, Nan Zhao, Mu Liu, Hai-Mo Shen, Lin Huang, X. Mo, Bin Xu, Xumin Zhang, Wei Hu

Frontiers in Microbiology

DOI

2017

Decoding the full picture of Raf1 function based on its interacting proteins

Ying Huang, Xiao-Xi Guo, B. Han, Xumin Zhang, Su An, Xin-Yi Zhang, Yang Yang, Ying Liu, Qian Hao, Tian-Rui Xu

OncoTarget

DOI

2016

An optimized guanidination method for large‐scale proteomic studies

Juanying Ye, Yang Zhang, Lin Huang, Qingqing Li, Jingnan Huang, Jia-Nan Lu, Yanhong Li, Xumin Zhang

Proteomics

DOI

2016

Abundant protein phosphorylation potentially regulates Arabidopsis anther development

Juanying Ye, Zai-Bao Zhang, C. You, Xumin Zhang, Jia-Nan Lu, Hong Ma

Journal of Experimental Botany

DOI

2015

Systematic Optimization of C-Terminal Amine-Based Isotope Labeling of Substrates Approach for Deep Screening of C-Terminome.

Yang Zhang, Quanze He, Juanying Ye, Yanhong Li, Lin Huang, Qingqing Li, Jingnan Huang, Jia-Nan Lu, Xumin Zhang

Analytical Chemistry

DOI

2015

Proteomic Analysis on Cercariae and Schistosomula in Reference to Potential Proteases Involved in Host Invasion of Schistosoma japonicum Larvae.

Mu Liu, C. Ju, Xiaodong Du, Hai-Mo Shen, Ji-Peng Wang, Jian Li, Xumin Zhang, Zheng Feng, Wei Hu

Journal of Proteome Research

DOI

2015

Proteomic and phosphoproteomic analyses reveal extensive phosphorylation of regulatory proteins in developing rice anthers.

Juanying Ye, Zai-Bao Zhang, Haifei Long, Zhi-Min Zhang, Yue Hong, Xumin Zhang, C. You, Wan-Qi Liang, Hong Ma, Pingli Lu

The Plant Journal

DOI

2013

Towards the N-terminal acetylome: an N-terminal acetylated peptide enrichment method using CNBr-activated sepharose resin.

Xumin Zhang, P. Højrup

Methods in molecular biology

DOI

2012

An on-target desalting and concentration sample preparation protocol for MALDI-MS and MS/MS analysis.

Xumin Zhang, Quanhui Wang, Xiaomin Lou, Hai-Dan Sun, P. Roepstorff, Siqi Liu

Methods in molecular biology

DOI

2011

A proteome‐scale study on in vivo protein Nα‐acetylation using an optimized method

Xumin Zhang, Juanying Ye, Kasper Engholm-Keller, P. Højrup

Proteomics

DOI

2010

Cyclization of the N-terminal X-Asn-Gly motif during sample preparation for bottom-up proteomics.

Xumin Zhang, P. Højrup

Analytical Chemistry

DOI

2010

Optimized IMAC-IMAC protocol for phosphopeptide recovery from complex biological samples.

Juanying Ye, Xumin Zhang, Clifford Young, Xiaolu Zhao, Qin Hao, Lei Cheng, O. Jensen

Journal of Proteome Research

DOI

2009

A proteomics approach to study in vivo protein N(alpha)-modifications.

Xumin Zhang, Juanying Ye, P. Højrup

Journal of Proteomics

DOI

2008

Optimization of immobilized metal ion affinity chromatography for phosphopeptide enrichment prior to mass spectrometry

Juanying Ye, Xumin Zhang, Clifford Young, E. Rudashevskaya, A. Nawrocki, M. Palmgren, A. Fuglsang, O. Jensen

2008

On-target sample preparation of 4-sulfophenyl isothiocyanate-derivatized peptides using AnchorChip Targets.

Xumin Zhang, A. Rogowska-Wrzesińska, P. Roepstorff

Journal of Mass Spectrometry

DOI

2007

Highly Efficient Phosphopeptide Enrichment by Calcium Phosphate Precipitation Combined with Subsequent IMAC Enrichment*S

Xumin Zhang, Juanying Ye, O. Jensen, P. Roepstorff

Molecular & Cellular Proteomics

DOI

2007

An improved method of sample preparation on AnchorChip™ targets for MALDI‐MS and MS/MS and its application in the liver proteome project

Xumin Zhang, Liang Shi, S. Shu, Yuan Wang, K. Zhao, Ning-Zhi Xu, Siqi Liu, P. Roepstorff

Proteomics

DOI

2007

Phosphorylation sites of Arabidopsis MAP kinase substrate 1 (MKS1).

M. Caspersen, Jin-Long Qiu, Xumin Zhang, E. Andreasson, H. Naested, J. Mundy, B. Svensson

Biochimica et Biophysica Acta

DOI

精选作品

期刊论文

Integrative Quantitative Proteomics and N‐Glycoproteomics Reveal Age‐Processing of N‐Glycosylation in Caenorhabditis elegans

An extensive forward genetic screen identifies the HWS-AGO1 axis as pivotal for target mimicry-mediated miRNA degradation in Arabidopsis.

Integrated Multi-omics Analysis Reveals that Hybrid Rice Reprograms Carbon Metabolism to Confer Drought Resistance.

The secreted elastase SjCE2b drives host skin penetration by Schistosoma japonicum

Gut microbial fucosidase unlocks the immunotherapy-enhancing potential of polysaccharides

SP3-PELSA: A rapid and sensitive approach for studying protein-ligand interaction with small-amount samples.

Quantitative Proteome and Phosphoproteome Profiling across Three Cell Lines Revealed Potential Proteins Relevant to Nasopharyngeal Carcinoma Metastasis.

102-Plex Approach for Accurate and Multiplexed Proteome Quantification.

Hydrophilic Peptide and Glycopeptide as Immobilized Sorbents for Glycosylation Analysis.

Annonaceous acetogenins mimic AA005 targets mitochondrial trifunctional enzyme alpha subunit to treat obesity in male mice

Mass spectrometry analysis of intact protein N-glycosylation signatures of cells and sera in pancreatic adenocarcinomas

Aspirin‐Mediated Acetylation of SIRT1 Maintains Intestinal Immune Homeostasis

Hyperplexing Approaches for up to 45-Plex Quantitative Proteomic Analysis.

Novel Approach to Enriching Glycosylated RNAs: Specific Capture of GlycoRNAs via Solid-Phase Chemistry.

Diagnostic Potential of Serum Glycome Analysis in Lung Cancer: A Glycopattern Study.

Mass Spectrometric Analysis of Urinary N-Glycosylation Changes in Patients with Parkinson's Disease.

Quantitative analysis of fucosylated glycoproteins by immobilized lectin-affinity fluorescent labeling

Isolation of biofluids from tissues using a vacuum-assisted filtration biomedical device.

SCFRMF mediates degradation of the meiosis-specific recombinase DMC1

Insight of novel biomarkers for papillary thyroid carcinoma through multiomics

20℃和25℃条件下秀丽隐杆线虫衰老过程中磷酸化蛋白质组学的研究

重组LysargiNase蛋白酶的表达纯化及其在蛋白质组学层面的分析

转录组和蛋白质组整合分析揭示组蛋白H2A去泛素化酶USP16的功能调控网络

TAG-TMTpro, a Hyperplexing Quantitative Approach for High-Throughput Proteomic Studies.

One-day thermal regime extends the lifespan in Caenorhabditis elegans

TOX4 facilitates promoter-proximal pausing and C-terminal domain dephosphorylation of RNA polymerase II in human cells

Mass Spectrometry-Based Analysis of Serum N-Glycosylation Changes in Patients with Parkinson's Disease.

Multi-Omics Analysis in β-Thalassemia Using an HBB Gene-Knockout Human Erythroid Progenitor Cell Model

Aberrant Fucosylation of Saliva Glycoprotein Defining Lung Adenocarcinomas Malignancy

Basic pH reversed-phase liquid chromatography (bRPLC) in combination with tip-based strong cation exchange (SCX-Tip), ReST, an efficient approach for large-scale cross-linked peptide analysis.

TOX4 Promotes Promoter Proximal Pause of RNA Polymerase Ii by Facilitating the Recruitment of DSIF and NELF

Author response: A muscle-epidermis-glia signaling axis sustains synaptic specificity during allometric growth in Caenorhabditis elegans

Tyrosine-EDC Conjugation, an Undesirable Side Effect of the EDC-Catalyzed Carboxyl Labeling Approach.

Formaldehyde Derivatization, an Unexpected Side Reaction During Filter-Aided Sample Preparation.

Basic Strong Cation Exchange Chromatography, BaSCX, a Highly Efficient Approach for C-Terminomic Studies Using LysargiNase Digestion.

A muscle-epidermis-glia signaling axis sustains synaptic specificity during allometric growth in Caenorhabditis elegans

Global Quantitative Proteomics Studies Revealed Tissue-Preferential Expression and Phosphorylation of Regulatory Proteins in Arabidopsis

Short-Term Mild Temperature-Stress-Induced Alterations in the C. elegans Phosphoproteome

Phosphorylation of Msx1 promotes cell proliferation through the Fgf9/18-MAPK signaling pathway during embryonic limb development

Msx1 cooperates with Runx1 for inhibiting myoblast differentiation.

基于质谱的蛋白质N末端乙酰化程度定量方法的研究

ADAMTS-family protease MIG-17 regulates synaptic allometry by modifying the extracellular matrix and modulating glia morphology during growth

Ubiquitylome study identifies increased histone 2A ubiquitylation as an evolutionarily conserved aging biomarker

蛋白质组学样品消化条件的优化

Enzyme and Chemical Assisted N-Terminal Blocked Peptides Analysis, ENCHANT, as a Selective Proteomics Approach Complementary to Conventional Shotgun Approach.

Revealing A-Raf functions through its interactome.

Lys-C/Arg-C, a More Specific and Efficient Digestion Approach for Proteomics Studies.

An Approach to Incorporate Multi‐Enzyme Digestion into C‐TAILS for C‐Terminomics Studies

Reversible Lysine Derivatization Enabling Improved Arg-C Digestion, a Highly Specific Arg-C Digestion Using Trypsin.

Quantitative phosphoproteomics reveals GTBP-1 regulating C.elegans lifespan at different environmental temperatures.

末端蛋白质组学研究进展

Comparative Analysis of Proteome-Wide Lysine Acetylation in Juvenile and Adult Schistosoma japonicum

Decoding the full picture of Raf1 function based on its interacting proteins

An optimized guanidination method for large‐scale proteomic studies

Abundant protein phosphorylation potentially regulates Arabidopsis anther development

Systematic Optimization of C-Terminal Amine-Based Isotope Labeling of Substrates Approach for Deep Screening of C-Terminome.

Proteomic Analysis on Cercariae and Schistosomula in Reference to Potential Proteases Involved in Host Invasion of Schistosoma japonicum Larvae.

Proteomic and phosphoproteomic analyses reveal extensive phosphorylation of regulatory proteins in developing rice anthers.

Towards the N-terminal acetylome: an N-terminal acetylated peptide enrichment method using CNBr-activated sepharose resin.

An on-target desalting and concentration sample preparation protocol for MALDI-MS and MS/MS analysis.

A proteome‐scale study on in vivo protein Nα‐acetylation using an optimized method

Cyclization of the N-terminal X-Asn-Gly motif during sample preparation for bottom-up proteomics.

Optimized IMAC-IMAC protocol for phosphopeptide recovery from complex biological samples.

A proteomics approach to study in vivo protein N(alpha)-modifications.

Optimization of immobilized metal ion affinity chromatography for phosphopeptide enrichment prior to mass spectrometry

On-target sample preparation of 4-sulfophenyl isothiocyanate-derivatized peptides using AnchorChip Targets.

Highly Efficient Phosphopeptide Enrichment by Calcium Phosphate Precipitation Combined with Subsequent IMAC Enrichment*S

An improved method of sample preparation on AnchorChip™ targets for MALDI‐MS and MS/MS and its application in the liver proteome project

Phosphorylation sites of Arabidopsis MAP kinase substrate 1 (MKS1).

会议论文

Schistosoma japonicum cathepsin B2(SjCB2) facilitates parasite invasion through the skin

预印本

eaFASP, Enhancing Filter-Aided Sample Preparation via Efficient Ethanol-Assisted Surfactant Removal

研究方向