李建华｜湖北工程学院｜学者主页

2025

Effect of structural changes of Rehmannia glutinosa polysaccharide before and after processing on anti-aging activity.

Ruixiang Shi, Si-Min Yang, Shu-Ting Zeng, Jia-Zi Lin, Xiao Wang, Jiamin Yu, Yefang Liang, Jianhua Li, Tong Zhou, Yong-An Deng, Xiao-Dong Duan, Cheng-Kai Chen, Miao Yu, Guibo Sun, Junzi Dong, Zun-Peng Shu

International Journal of Biological Macromolecules

DOI

2025

Research progress on the anti‐aging effect of polysaccharides of traditional Chinese medicine: Using Caenorhabditis elegans as an animal model

Jia-Zi Lin, Jiamin Yu, Xiao Wang, Ruixiang Shi, Yefang Liang, Jianhua Li, Tong Zhou, Cheng-Kai Chen, Xiao-Dong Duan, Yong-An Deng, Si-Min Yang, Shu-Ting Zeng, Xuejuan Shen, Xiang-Yu Chen, Yi Wang, Guibo Sun, Zun-Peng Shu

The FASEB Journal

DOI

2025

Novel insights into immune mechanisms in acute lung injury: Focusing on gut microbiota and its metabolites.

Cheng-Kai Chen, Jia-Zi Lin, Xiao Wang, Si-Min Yang, Xiao-Dong Duan, Yong-An Deng, Shu-Ting Zeng, Tong Zhou, Jianhua Li, Jiamin Yu, Yefang Liang, Xuejuan Shen, Ruixiang Shi, Yi Wang, Zun-Peng Shu

Microbiology Research

DOI

2025

Elucidation of the Potential Molecular Mechanisms of Buyang Huanwu Decoction in Delaying Cardiac Aging: Based on Network Pharmacology, Bioinformatics, and In Vivo/In Vitro Experimental Validation.

Xiao-Dong Duan, Yong-An Deng, Minghao Feng, Cheng-Kai Chen, Si-Min Yang, Shu-Ting Zeng, Xiao-Die Chen, Nan Xiao, Xiang-Yu Chen, Jianhua Li, Yi-Xuan Huang, Yu-Tong Yang, Min Yu, Guangwei Wang, Wenrong Yu, Li Zhang, Yi Wang, Zun-Peng Shu

Journal of Ethnopharmacology

DOI

2024

Research on the Mechanism of Buyang Huanwu Decoction in the Amelioration of Age-Associated Memory Impairment Based on the "Co-occurrence Network Regulation of Intestinal Microecology-Host Metabolism-Immune Function".

Caiyan Liu, Jie Du, Ji Yang, Jianhua Li, Tong Zhou, Jiamin Yu, Xiao Wang, Jia-Zi Lin, Yefang Liang, Ruixiang Shi, Rongfeng Luo, Xuejuan Shen, Yi Wang, Li Zhang, Zun-Peng Shu

Journal of Ethnopharmacology

DOI

2024

Multi-metabolomics and intestine microbiome analysis: YZC extract ameliorates septic-ALI by modulating intestine microbiota to reduce TMAO/NLRP3 signaling.

Xia Cao, Mantong Zhao, Xiao Wang, Jia-Zi Lin, Mengru Yang, Luyang Zhong, Lanyuan Liang, Yi-Nan Yue, Jie Du, Jianhua Li, Tong Zhou, Jiamin Yu, Yefang Liang, Ruixiang Shi, Rongfeng Luo, Xuejuan Shen, Ying Chen, Yi Wang, Zun-Peng Shu

Phytomedicine

DOI

2024

Gegen Qinlian Decoction improves H1N1-induced viral pneumonia by modulating the "gut microbiota-metabolomics-immune/inflammation" axis.

Tong Zhou, Jianhua Li, Wei Li, Jiamin Yu, Yong-An Deng, Xiao-Dong Duan, Jia-Zi Lin, Xiao Wang, Yefang Liang, Chongyang Zhang, Miao Yu, Ruixiang Shi, Cheng-Kai Chen, Si-Min Yang, Shu-Ting Zeng, Xuejuan Shen, Yi Wang, Jing Sun, Zun-Peng Shu

International Immunopharmacology

DOI

2024

Multi-immunometabolomics mining: NP prevents hyperimmune in ALI by inhibiting Leucine/PI3K/Akt/mTOR signaling pathway.

Mantong Zhao, Jia-Zi Lin, Xiao Wang, Cheng-Kai Chen, Jianhua Li, Jiamin Yu, Tong Zhou, Yefang Liang, Xuejuan Shen, Ruixiang Shi, Si-Min Yang, Shu-Ting Zeng, Yong-An Deng, Xiao-Dong Duan, Li-Chang Zhou, Xiao-Bo Sun, Yi Wang, Zun-Peng Shu

Free Radical Biology & Medicine

DOI

2024

Research on Traditional Chinese Medicine as an effective drug for promoting wound healing.

Tong Zhou, Chongyang Zhang, Xiao Wang, Jia-Zi Lin, Jiamin Yu, Yefang Liang, Huilin Guo, Mengru Yang, Xuejuan Shen, Jianhua Li, Ruixiang Shi, Yi Wang, Ji Yang, Zun-Peng Shu

Journal of Ethnopharmacology

DOI

2024

利用酵母细胞工厂合成丁二酸的研究进展

钟驭涛，尚长宇，王言东，李建华，刘成才，崔志勇，祁庆生

《生物工程学报》

2023

Anemarrhena asphodeloides Bunge total saponins ameliorate diabetic cardiomyopathy by modifying the PI3K/AKT/HIF-1α pathway to restore glycolytic metabolism.

Luyang Zhong, Jianhua Li, Jiamin Yu, Xia Cao, Jie Du, Lanyuan Liang, Mengru Yang, Yi-Nan Yue, Mantong Zhao, Tong Zhou, Jia-Zi Lin, Xiao Wang, Xuejuan Shen, Yanmei Zhong, Yi Wang, Zun-Peng Shu

Journal of Ethnopharmacology

DOI

2021

发酵食品微生物多样性分析方法研究进展

夏傲喃，李建华，林祥娜，汤晓娟，刘云国

《食品研究与开发》

2019

工矿复垦区大豆根际微生物多样性对施肥制度的响应

张变华，靳东升，郜春花，郜雅静，李建华

《江苏农业科学》

DOI

2019

不同方法分析工矿复垦区不同植物根际微生物多样性的比较

张变华，靳东升，郜春花，郜雅静，李建华

《江苏农业科学》

DOI

2016

蔬菜废弃物资源化利用—生产乳牛混合饲料

陈静静，李建华，TAKAHASHI JUNICHI，陈郡楠

《中国科技信息》

2016

响应曲面法优化石榴皮总黄酮提取工艺

邓婷婷，李建华，肖本胜，郑琦锴，宋阳

《湖北工程学院学报》

2014

复合酶法提取黄秋葵嫩果多酚的工艺优化

汪殿蓓，李建华

《天然产物研究与开发》

2014

响应曲面法优化桑椹黄酮的超声提取工艺

袁玲，李建华

《湖北工程学院学报》

2014

烟草连作对土壤微生物多样性及酶活性的影响

焦永吉，程功，马永健，王伟超，李建华，乔保明，蒋士君

《土壤与作物》

2013

桑椹原花青素提取的响应曲面优化分析

袁玲，李建华

《湖北工程学院学报》

2011

化学处理方法对木质纤维素降解效率的影响评述

李建华，张越，刘仲齐

《生物技术进展》

2010

矿区土壤微生物多样性研究概述

范继香，郜春花，卢朝东，张强，靳东升，李建华

《山西农业科学》

2008

石灰华扇(Tufa Fan)沉积物中的微型生物多样性

王智慧，张朝晖，李建华

《沉积学报》

2007

广西西部石灰岩地区生物多样性保护意义与持续利用设想

李建华，王献溥，许立明，覃海宁

《广西植物》

2006

农业循环经济与废弃物资源化利用策略

李伟伟，刘荣章，李建华

《台湾农业探索》

1997

膜反应器及其在生物催化过程中的应用与前景

李建华

《长春师范大学学报》

李建华

精选作品

期刊论文

Effect of structural changes of Rehmannia glutinosa polysaccharide before and after processing on anti-aging activity.

Research progress on the anti‐aging effect of polysaccharides of traditional Chinese medicine: Using Caenorhabditis elegans as an animal model

Novel insights into immune mechanisms in acute lung injury: Focusing on gut microbiota and its metabolites.

Elucidation of the Potential Molecular Mechanisms of Buyang Huanwu Decoction in Delaying Cardiac Aging: Based on Network Pharmacology, Bioinformatics, and In Vivo/In Vitro Experimental Validation.

Research on the Mechanism of Buyang Huanwu Decoction in the Amelioration of Age-Associated Memory Impairment Based on the "Co-occurrence Network Regulation of Intestinal Microecology-Host Metabolism-Immune Function".

Multi-metabolomics and intestine microbiome analysis: YZC extract ameliorates septic-ALI by modulating intestine microbiota to reduce TMAO/NLRP3 signaling.

Gegen Qinlian Decoction improves H1N1-induced viral pneumonia by modulating the "gut microbiota-metabolomics-immune/inflammation" axis.

Multi-immunometabolomics mining: NP prevents hyperimmune in ALI by inhibiting Leucine/PI3K/Akt/mTOR signaling pathway.

Research on Traditional Chinese Medicine as an effective drug for promoting wound healing.

利用酵母细胞工厂合成丁二酸的研究进展

Anemarrhena asphodeloides Bunge total saponins ameliorate diabetic cardiomyopathy by modifying the PI3K/AKT/HIF-1α pathway to restore glycolytic metabolism.

发酵食品微生物多样性分析方法研究进展

工矿复垦区大豆根际微生物多样性对施肥制度的响应

不同方法分析工矿复垦区不同植物根际微生物多样性的比较

蔬菜废弃物资源化利用—生产乳牛混合饲料

响应曲面法优化石榴皮总黄酮提取工艺

复合酶法提取黄秋葵嫩果多酚的工艺优化

响应曲面法优化桑椹黄酮的超声提取工艺

烟草连作对土壤微生物多样性及酶活性的影响

桑椹原花青素提取的响应曲面优化分析

化学处理方法对木质纤维素降解效率的影响评述

矿区土壤微生物多样性研究概述

石灰华扇(Tufa Fan)沉积物中的微型生物多样性

广西西部石灰岩地区生物多样性保护意义与持续利用设想

农业循环经济与废弃物资源化利用策略

膜反应器及其在生物催化过程中的应用与前景

研究方向