乔亮｜复旦大学｜学者主页

2026

“101计划”《化学测量学实验动态电子教案》数字化教材的设计与建设

张来英，吴伟泰，袁汝明，淳远，乔亮，方宁，雷杰，徐伟高，许新华，张志敏，郑成斌，朱平平，颜佳伟，任斌

《大学化学》

2026

Deep Understanding of Vaginal Microbiota in HPV‐Related Diseases From a Multi‐Omics Perspective

Jianxujie Zheng, Qing Cong, L Lin, Liang Qiao

VIEW Medicine

DOI

2026

Response to “Comment on ‘Unsupervised Machine Learning for Differential Analysis in Proteomics’ ”

Guanyang Xu, Liang Qiao

Analytical Chemistry

DOI

2026

Deep Learning Prediction of O‐Glycopeptide Tandem Mass Spectra Enhances O‐Glycoproteomics

Yu Zong, Yu-Xin Wang, Liang Qiao

Advancement of science

DOI

2026

AI-driven precise proteomics

Guanyang Xu, Liang Qiao

Chinese Science Bulletin

DOI

2026

Minimally Invasive Single-Cell Metabolomics Analysis to Unveil Different Trajectories of Individual Cells in Ferroptosis.

Dandan Xia, Rong Jin, Le Tong, Wei Han, Liang Qiao, De-Chen Jiang

Analytical Chemistry

DOI

2026

Fusing serum peptidome profiles with clinical variables via machine learning for pulmonary embolism risk assessment.

Jia Yi, Tian Lan, Hai-Su Lu, Yini Song, Dan Zhao, Zi-Chen Xie, Liang Qiao, Keyu Sun

Talanta: The International Journal of Pure and Applied Analytical Chemistry

DOI

2026

AI proteomics: from protein identification to virtual cells

Yingying Sun, A. Jun, Zhi-Wei Liu, R. Sun, Liujia Qian, Samuel H. Payne, Wout Bittremieux, M. Ralser, Chen Li, Yi Chen, Zhen Dong, Yasset Pérez-Riverol, Asif Khan, Chris Sander, R. Aebersold, J. Vizcaíno, Jonathan R. Krieger, Jian-Hua Yao, Wenxiang Han, Lin-Feng Zhang, Yunping Zhu, Y. Xuan, Benjamin B. Sun, Liang Qiao, H. Hermjakob, Haixu Tang, Huanhuan Gao, Ya-Min Deng, Qing Zhong, Cheng Chang, Nuno Bandeira, Ming Li, W. E, Si-Qi Sun, Yue-Dong Yang, G. Omenn, Yue Zhang, Ping Xu, Yan Fu, Xiaowen Liu, Christopher M. Overall, Yu Wang, Eric W. Deutsch, Luonan Chen, J. Cox, Vadim Demichev, Fu-Chu He, Jia-Xing Huang, Hui-Lin Jin, Chao Liu, Nan Li, Zhong-Zhi Luan, Jiang-Ning Song, Kaicheng Yu, Wang-Gen Wan, Tai Wang, Kang Zhang, Le Zhang, Peter A. Bell, Matthias Mann, Bing Zhang, Tian-Nan Guo

Nature Methods

DOI

2026

Mass spectrometry-based single-cell metabolomics and metabolic tracing analysis

Xin-ying Zhu, Jia Yi, Liang Qiao

Trends in Analytical Chemistry (TrAC)

DOI

2026

Mitochondrial Omics in Macrophage Foam Cell Formation and Atherosclerosis.

Enhui Wu, Zengyu Wang, Yiwen Wang, Liang Qiao, Dong Xie

Proteomics

DOI

2025

Machine Learning-Driven Extracellular Vesicles Peptidomics Powers Precision Classification of Endometrial Cancer

Yunhan Yang, Dandan Li, Pengfei Wu, Haonan Yang, Jia Yi, Dan Zhao, Jiawei Yu, Ji Ji, Xiaojun Chen, Liang Qiao

Analytical Chemistry

DOI

2025

Integrated multi‐omics analysis reveals metabolic reprogramming as a key driver of angiotensin II‐induced vascular remodeling

Yiwei Hu, Dan Zhao, Lingyan Zhong, Jianxujie Zheng, Dongxue Zhang, Enhui Wu, Qian Shi, Liang Qiao, Ling Lin

Open Research (University of Surrey)

DOI

2025

Unsupervised Machine Learning for Differential Analysis in Proteomics

Guanyang Xu, Enhui Wu, Yuxiang Lin, Ling Lin, Liang Qiao

Analytical Chemistry

DOI

2025

DeepSecMS Advances DIA‐Based Selenoproteome Profiling Through Cys‐to‐Sec Proxy Training

Chenfang Si, Yamei Yuan, Yu Zong, Liang Qiao, Wen‐Feng Zeng, Yaoyang Zhang

Advanced Science

DOI

2025

Vessel‐On‐A‐Chip Coupled Proteomics Reveal Pressure‐Overload‐Induced Vascular Remodeling

Y. Liu, Jianxujie Zheng, Lingyan Zhong, Zeng-Yu Wang, Dan Zhao, Honghui Lin, Xiaoxue Zhang, Ke Meng, Xiaoxia Yang, Dongxue Zhang, Ling Lin, Liang Qiao

Advanced Science

DOI

2024

微生物宏蛋白质组——从样品处理、数据采集到数据分析

Enhui Wu, Liang Qiao

Se pu = Chinese journal of chromatography

DOI

2024

生物质谱在生物制品宿主细胞蛋白残留分析中的应用

谢力琦，王静，朱添怡，王佳馨，黄懿，乔亮

《质谱学报》

2024

蛋白质组学专刊

龙亿涛，乔亮，万晶晶

《高等学校化学学报》

2024

非靶向脂质组学揭示巨噬细胞泡沫化进程脂质代谢功能失调

汪增钰，刘宝红，乔亮，林灵

《高等学校化学学报》

2024

Efficient serum lipids profiling by TiO2-dopamin-assisted MALDI-TOF MS for breast cancer detection

Xinyue Han, Yunhan Yang, Jiayin Lu, Yu-Xiang Lin, Dongxue Zhang, Ling Lin, Liang Qiao

Chinese Chemical Letters

DOI

2024

化学“101计划”化学测量学实验课程设计

吴伟泰，张来英，淳远，乔亮，任斌

《大学化学》

2024

Diagnosis and Biomarker Screening of Endometrial Cancer Enabled by a Versatile Exosome Metabolic Fingerprint Platform

Haonan Yang, Pengfei Wu, Binxiao Li, Xuedong Huang, Qian Shi, Liang Qiao, Baohong Liu, Xiaojun Chen, Xiaoni Fang

Analytical Chemistry

DOI

2024

MALDI‐TOF MS analysis of nasal swabs for the characterization of patients infected with SARS‐CoV‐2 Omicron

Rui Song, Dandan Li, Xiaohua Hao, Qian Lyu, Qingwei Ma, Xiaoyou Chen, Liang Qiao

Open Research (University of Surrey)

DOI

2024

MazF-rolling circle amplification combined MALDI-TOF MS for site-specific detection of N6-methyladenosine RNA.

Guo-Bin Han, Qiu-Yuan Lin, Jia Yi, Qian Lyu, Qing-Wei Ma, Liang Qiao

Analytica Chimica Acta

DOI

2024

Multiplexed discrimination of SARS-CoV-2 variants via duplex-specific nuclease combined MALDI-TOF MS

Guo-Bin Han, Wen-Chan Deng, Qian Lyu, Qing-Wei Ma, Liang Qiao

Analytical and Bioanalytical Chemistry

DOI

2024

Single-Cell Time-Resolved Metabolomics and Lipidomics Reveal Apoptotic and Ferroptotic Heterogeneity during Foam Cell Formation.

Yiwen Wang, Zengyu Wang, Yun-Zeng Zou, Ling Lin, Liang Qiao

Analytical Chemistry

DOI

2024

Data-independent acquisition in metaproteomics

Enhui Wu, Guanyang Xu, Dong-Qing Xie, Liang Qiao

Espert Review of Proteomics

DOI

2024

Quantitative Site-Specific Glycoproteomics Reveals Glyco-Signatures for Breast Cancer Diagnosis.

Yi Yang, Dan Zhao, Ji Luo, Ling Lin, Yu-Xiang Lin, Baozhen Shan, Hong-Xu Chen, Liang Qiao

Analytical Chemistry

DOI

2024

High-Abundance Protein-Guided Hybrid Spectral Library for Data-Independent Acquisition Metaproteomics.

Enhui Wu, Yi Yang, Jinzhi Zhao, J. Zheng, Xiaoqing Wang, Chengpin Shen, Liang Qiao

Analytical Chemistry

DOI

2024

Metabolomics and proteomics reveal the inhibitory effect of Lactobacillus crispatus on cervical cancer.

Lingyan Zhong, J. Zheng, Zengyu Wang, Ling Lin, Q. Cong, Liang Qiao

Talanta: The International Journal of Pure and Applied Analytical Chemistry

DOI

2024

Deep Learning Powers Protein Identification from Precursor MS Information.

Ya-Meng Dai, Yi Yang, Enhui Wu, Chengpin Shen, Liang Qiao

Journal of Proteome Research

DOI

2024

Integrative Proteomic and Metabolomic Elucidation of Cardiomyopathy with in vivo, in vitro Models and Clinical Samples.

Yi-Wei Hu, Yun-Zeng Zou, Liang Qiao, Ling Lin

Molecular Therapy

DOI

2024

Deep Learning Prediction of Glycopeptide Tandem Mass Spectra Powers Glycoproteomics

Yu Zong, Yu-Xin Wang, Xi-Peng Qiu, Xuanjing Huang, Liang Qiao

bioRxiv

DOI

2023

微流控芯片技术及质谱技术用于细菌耐药性检测及耐药机制研究

张冬雪，乔亮

《中国药科大学学报》

2023

Exponential isothermal amplification coupled MALDI-TOF MS for microRNAs detection

Guobin Han, Dandan Li, Qiuyuan Lin, Jia Yi, Qian Lyu, Qingwei Ma, Liang Qiao

Chinese Chemical Letters

2023

Recent developments in organ-on-a-chip technology for cardiovascular disease research

Yanjun Liu, Ling Lin, Liang Qiao

Analytical and Bioanalytical Chemistry

DOI

2023

Microfluidics Coupled Mass Spectrometry for Single Cell Multi‐Omics

Dongxue Zhang, Liang Qiao

Small Methods

DOI

2022

Data‐independent acquisition proteomics methods for analyzing post‐translational modifications

Yi Yang, Liang Qiao

PROTEOMICS

DOI

2022

Microfluidic Free‐Flow Paper Electrochromatography for Continuous Separation of Glycans

Yingchao Liu, Yuanyu Huang, Mengxi Wu, Siyuan Kong, Weiqian Cao, Shunxiang Li, Guoquan Yan, Baohong Liu, Pengyuan Yang, Quanqing Zhang, Liang Qiao, Huali Shen

ChemElectroChem

DOI

2022

Isothermal gene amplification coupled MALDI-TOF MS for SARS-CoV-2 detection

Guo-Bin Han, Qiu-Yuan Lin, Jia Yi, Qian Lyu, Qing-Wei Ma, Liang Qiao

Talanta: The International Journal of Pure and Applied Analytical Chemistry

DOI

2022

Ultrasensitive Analysis of Exosomes Using a 3D Self-Assembled Nanostructured SiO2 Microfluidic Chip.

Qiaoyu Li, Yan-Lin Wang, Yuyan Xue, Liang Qiao, Guo-Peng Yu, Yushan Liu, Shao-Ning Yu

ACS Applied Materials and Interfaces

DOI

2021

Highly efficient enrichment and identification of pathogens using a herringbone microfluidic chip and by MALDI-TOF mass spectrometry

Yueqing Shen, Jia Yi, Minghui Song, Dandan Li, Yi Wu, Yan‐Jun Liu, Meicheng Yang, Liang Qiao

The Analyst

DOI

2021

Rapid Detection of COVID-19 Using MALDI-TOF-Based Serum Peptidome Profiling

Ling Yan, Jia Yi, Changwu Huang, Jian Zhang, S. Fu, Zhi-Jie Li, Qian Lyu, Yuan Xu, Kun Wang, Huanzhen Yang, Qing-wei Ma, Xiao-Ping Cui, Liang Qiao, Wei Sun, P. Liao

Analytical Chemistry

DOI

2021

Urinary Proteomics of Simulated Firefighting Tasks and Its Relation to Fitness Parameters

T. Zhu, Yuxian Hu, Jooyeon Hwang, Dan Zhao, Libin Huang, Liang Qiao, An-Kui Wei, Xin Xu

International Journal of Environmental Research and Public Health

DOI

2020

Microfluidic filter device coupled mass spectrometry for rapid bacterial antimicrobial resistance analysis

Dongxue Zhang, Yijie Zhang, Fan Yin, Qin Qin, Hongyan Bi, Baohong Liu, Liang Qiao

The Analyst

DOI

2020

Microfluidic Raman biochip detection of exosomes: a promising tool for prostate cancer diagnosis

Yanlin Wang, Qiaoyu Li, Haimei Shi, Keqi Tang, Liang Qiao, Guopeng Yu, Chuan‐Fan Ding, Shaoning Yu

Lab on a Chip

DOI

2019

Differentiation and authentication of fishes at the species level through analysis of fish skin by matrix‐assisted laser desorption/ionization time‐of‐flight mass spectrometry

Hongyan Bi, Chunyi Zhong, Mingke Shao, Chengyu Wang, Jia Yi, Liang Qiao, Junbo Zhang

Rapid Communications in Mass Spectrometry

DOI

2018

Electrostatic Spray Ionization-Mass Spectrometry for Direct and Fast Wine Characterization

Hongyan Bi, Minjie Xi, Rutan Zhang, Chengyu Wang, Liang Qiao, Jing Xie

ACS Omega

DOI

2018

The Competitive Dynamic Binding of Some Blood Proteins Adsorbed on Gold Nanoparticles

Xiaoning Zhang, Haimei Shi, Rutan Zhang, Junting Zhang, Fuxing Xu, Liang Qiao, Shaoning Yu

Particle & Particle Systems Characterization

DOI

2018

Toward Spectral Library-Free Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry Bacterial Identification

Ding Cheng, Liang Qiao, Peter L. Horvatovich

Journal of Proteome Research

DOI

2018

Detection of antimicrobial resistance-associated proteins by titanium dioxide-facilitated intact bacteria mass spectrometry

Yingdi Zhu, Natalia Gasilova, Milica Jović, Liang Qiao, Baohong Liu, Lysiane Tissières Lovey, Horst Matthias Pick, Hubert H. Girault

Chemical Science

DOI

2018

Ultrasensitive profiling of multiple biomarkers from single cells by signal amplification mass spectrometry

Yuning Wang, Ruijun Du, Liang Qiao, Baohong Liu

Chemical Communications

DOI

2017

Bacterial Whole Cell Typing by Mass Spectra Pattern Matching with Bootstrapping Assessment

Yi Yang, Yu Lin, Zhuoxin Chen, Tianqi Gong, Pengyuan Yang, Hubert H. Girault, Baohong Liu, Liang Qiao

Analytical Chemistry

DOI

2017

Electrochemistry-mass spectrometry for mechanism study of oxygen reduction at water/oil interface

Shujuan Liu, Zhengwei Yu, Liang Qiao, Baohong Liu

Scientific Reports

DOI

2016

Microfluidic Air Sampler for Highly Efficient Bacterial Aerosol Collection and Identification

Xiaojun Bian, Ying Lan, Bing Wang, Yu Shrike Zhang, Baohong Liu, Pengyuan Yang, Weijia Zhang, Liang Qiao

Analytical Chemistry

DOI

2016

Sensitive and fast beverage/fruit antioxidant evaluation by TiO 2 ‐Au/graphene nanocomposites coupled with MALDI‐MS

Xiaoni Fang, Kun Zhang, Pengyuan Yang, Liang Qiao, Baohong Liu

Rapid Communications in Mass Spectrometry

DOI

2016

Ultrasensitive Detection of Low-Abundance Protein Biomarkers by Mass Spectrometry Signal Amplification Assay

Ruijun Du, Li‐Na Zhu, Jinrui Gan, Yuning Wang, Liang Qiao, Baohong Liu

Analytical Chemistry

DOI

2009

基质辅助激光解析离子化研究及其在蛋白质组学中的应用

乔亮

《复旦大学》

精选作品

期刊论文

质谱：微观世界的一杆秤

“101计划”《化学测量学实验动态电子教案》数字化教材的设计与建设

Deep Understanding of Vaginal Microbiota in HPV‐Related Diseases From a Multi‐Omics Perspective

Response to “Comment on ‘Unsupervised Machine Learning for Differential Analysis in Proteomics’ ”

Deep Learning Prediction of O‐Glycopeptide Tandem Mass Spectra Enhances O‐Glycoproteomics

AI-driven precise proteomics

Minimally Invasive Single-Cell Metabolomics Analysis to Unveil Different Trajectories of Individual Cells in Ferroptosis.

Fusing serum peptidome profiles with clinical variables via machine learning for pulmonary embolism risk assessment.

AI proteomics: from protein identification to virtual cells

Mass spectrometry-based single-cell metabolomics and metabolic tracing analysis

Mitochondrial Omics in Macrophage Foam Cell Formation and Atherosclerosis.

Machine Learning-Driven Extracellular Vesicles Peptidomics Powers Precision Classification of Endometrial Cancer

Integrated multi‐omics analysis reveals metabolic reprogramming as a key driver of angiotensin II‐induced vascular remodeling

Unsupervised Machine Learning for Differential Analysis in Proteomics

DeepSecMS Advances DIA‐Based Selenoproteome Profiling Through Cys‐to‐Sec Proxy Training

Vessel‐On‐A‐Chip Coupled Proteomics Reveal Pressure‐Overload‐Induced Vascular Remodeling

微生物宏蛋白质组——从样品处理、数据采集到数据分析

生物质谱在生物制品宿主细胞蛋白残留分析中的应用

蛋白质组学专刊

非靶向脂质组学揭示巨噬细胞泡沫化进程脂质代谢功能失调

Efficient serum lipids profiling by TiO2-dopamin-assisted MALDI-TOF MS for breast cancer detection

化学“101计划”化学测量学实验课程设计

Diagnosis and Biomarker Screening of Endometrial Cancer Enabled by a Versatile Exosome Metabolic Fingerprint Platform

MALDI‐TOF MS analysis of nasal swabs for the characterization of patients infected with SARS‐CoV‐2 Omicron

MazF-rolling circle amplification combined MALDI-TOF MS for site-specific detection of N6-methyladenosine RNA.

Multiplexed discrimination of SARS-CoV-2 variants via duplex-specific nuclease combined MALDI-TOF MS

Single-Cell Time-Resolved Metabolomics and Lipidomics Reveal Apoptotic and Ferroptotic Heterogeneity during Foam Cell Formation.

Data-independent acquisition in metaproteomics

Quantitative Site-Specific Glycoproteomics Reveals Glyco-Signatures for Breast Cancer Diagnosis.

High-Abundance Protein-Guided Hybrid Spectral Library for Data-Independent Acquisition Metaproteomics.

Metabolomics and proteomics reveal the inhibitory effect of Lactobacillus crispatus on cervical cancer.

Deep Learning Powers Protein Identification from Precursor MS Information.

Integrative Proteomic and Metabolomic Elucidation of Cardiomyopathy with in vivo, in vitro Models and Clinical Samples.

Deep Learning Prediction of Glycopeptide Tandem Mass Spectra Powers Glycoproteomics

微流控芯片技术及质谱技术用于细菌耐药性检测及耐药机制研究

Exponential isothermal amplification coupled MALDI-TOF MS for microRNAs detection

Recent developments in organ-on-a-chip technology for cardiovascular disease research

Microfluidics Coupled Mass Spectrometry for Single Cell Multi‐Omics

Data‐independent acquisition proteomics methods for analyzing post‐translational modifications

Microfluidic Free‐Flow Paper Electrochromatography for Continuous Separation of Glycans

Isothermal gene amplification coupled MALDI-TOF MS for SARS-CoV-2 detection

Ultrasensitive Analysis of Exosomes Using a 3D Self-Assembled Nanostructured SiO2 Microfluidic Chip.

Highly efficient enrichment and identification of pathogens using a herringbone microfluidic chip and by MALDI-TOF mass spectrometry

Rapid Detection of COVID-19 Using MALDI-TOF-Based Serum Peptidome Profiling

Urinary Proteomics of Simulated Firefighting Tasks and Its Relation to Fitness Parameters

Microfluidic filter device coupled mass spectrometry for rapid bacterial antimicrobial resistance analysis

Microfluidic Raman biochip detection of exosomes: a promising tool for prostate cancer diagnosis

Differentiation and authentication of fishes at the species level through analysis of fish skin by matrix‐assisted laser desorption/ionization time‐of‐flight mass spectrometry

Electrostatic Spray Ionization-Mass Spectrometry for Direct and Fast Wine Characterization

The Competitive Dynamic Binding of Some Blood Proteins Adsorbed on Gold Nanoparticles

Toward Spectral Library-Free Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry Bacterial Identification

Detection of antimicrobial resistance-associated proteins by titanium dioxide-facilitated intact bacteria mass spectrometry

Ultrasensitive profiling of multiple biomarkers from single cells by signal amplification mass spectrometry

Bacterial Whole Cell Typing by Mass Spectra Pattern Matching with Bootstrapping Assessment

Electrochemistry-mass spectrometry for mechanism study of oxygen reduction at water/oil interface

Microfluidic Air Sampler for Highly Efficient Bacterial Aerosol Collection and Identification

Sensitive and fast beverage/fruit antioxidant evaluation by TiO 2 ‐Au/graphene nanocomposites coupled with MALDI‐MS

Ultrasensitive Detection of Low-Abundance Protein Biomarkers by Mass Spectrometry Signal Amplification Assay

基质辅助激光解析离子化研究及其在蛋白质组学中的应用

会议论文

基于微流控芯片-质谱联用的细菌耐药分析

微纳分析系统用于单细胞生物分子高灵敏度检测

基于质谱技术的非靶向检测微生物新算法、新技术

New Algorithm for MALDI-TOF MS Fingerprinting Based Bacterial Identification

Identification of pathogenic bacteria from human blood using IgG modified Fe 3 O 4 magnetic beads as a sorbent and MALDI-TOF MS for profiling

TiO 2 -LDI-TOF快速检测细菌代谢物及用于细菌耐药性识别研究

一种快速的高分辨质谱信号处理方法用于定量蛋白质组学

基于光电氧化还原的离子源内蛋白质分析研究

预印本

MALDI-TOF Mass Spectrometry Profiling of Plasma Exosomes Evaluates Osteosarcoma Metastasis

研究方向