罗孟成｜武汉大学｜学者主页

2026

DAXX governs the silencing of LINE1 during spermatogenesis in mice

Zejia Li, Chaoyang Xiong, Jin Shen, C. Tan, Dupeng Ma, Jun Chen, Rong Liu, Qi Sun, Weihao Gong, Wenming Yuan, Mengya Huang, Li Huang, Yueqiu Tan, Guo-Hong Li, Mengcheng Luo

Nucleic Acids Research

DOI

2025

Ubap2基因敲除对小鼠精子发生及生育能力的影响

段超群，邓星，孙齐，刘勺志，罗孟成，周俊，彭伟，吕丹，韩艳

《武汉大学学报(医学版)》

DOI

2025

Loss of TEX30 leads to male subfertility in mice.

Qi Sun, Zejia Li, Binyi Wang, Muyang Cheng, Jin Shen, Mengcheng Luo, Rong Liu

Biology of Reproduction

DOI

2025

New feature of hMEIOB and hSPATA22 binding to ssDNA from a single-molecule perspective

Yating Xu, Wei Qu, Erchi Zhou, Qi Sun, Weihao Gong, Lei Xu, Yaoke Lei, Zhangying Jia, Hanqing Shi, Xinghua Zhang, Mengcheng Luo

Acta Biochimica et Biophysica Sinica

DOI

2024

Microfluidic thermotaxic selection of highly motile sperm and in vitro fertilization

Sihan Chen, Jiemin Chen, Zihan Qin, Jibo Wang, Yuwen Wang, Rong Liu, Wen Zhao, Ming Zhang, Yuan-Zhen Zhang, Mengcheng Luo, Pu Chen

Bio-Design and Manufacturing

DOI

2024

PWWP3A deficiency accelerates testicular senescence in aged mice

Zhen Chen, Cong Liu, Wei Qu, Yan Han, Xiaoyu Zhu, Zejia Li, Dupeng Ma, Mengya Huang, Weihao Gong, Qi Sun, Junhao Lei, Rui Guo, Mengcheng Luo

Andrology

DOI

2024

Berberine alters the gut microbiota metabolism and impairs spermatogenesis

Wei Qu, Yu-Min Xu, Jing Yang, Hanqing Shi, Junli Wang, Xinnai Yu, Jiemin Chen, Binyi Wang, Deqing Zhuoga, Mengcheng Luo, Rong Liu

Acta Biochimica et Biophysica Sinica

DOI

2024

Editorial: Mammalian spermatogenesis: genetic and environmental factors

Wei Qu, Xinnai Yu, Hanqing Shi, Zhiyi Chen, Mengcheng Luo

Frontiers in Cell and Developmental Biology

DOI

2023

The DOT1L-MLLT10 complex regulates male fertility and promotes histone removal during spermiogenesis.

Huijuan Lin, Isabella G Cossu, N. Leu, A. Deshpande, K. Bernt, Mengcheng Luo, P. Wang

Development

DOI

2022

MicroRNA‐202 safeguards meiotic progression by preventing premature SEPARASE‐mediated REC8 cleavage

Jian Chen, Chenxu Gao, Mengcheng Luo, Chunwei Zheng, Xiwen Lin, Yan Ning, Longfei Ma, Wei He, Dan Xie, Kui Liu, Kai Hong, Chunsheng Han

EMBO Reports

DOI

2022

Identification and characterization of BEND2 as a key regulator of meiosis during mouse spermatogenesis

Longfei Ma, Danning Xie, Mengcheng Luo, Xiwen Lin, Hengyu Nie, Jian Chen, Chenxu Gao, Shu-Guang Duo, Chun-Sheng Han

Science Advances

DOI

2022

Fbxw17 is dispensable for viability and fertility in mice

Zhen Chen, Dupeng Ma, Ting-Yu Jin, Ziqi Yu, Jiong Li, Qi Sun, Zejia Li, Ziye Du, Rong Liu, Yi Li, Mengcheng Luo

Molecular Biology Reports

DOI

2022

Editorial: Reproductive genomics

Rong Liu, Y. Yun, Wen-Jie Shu, Xi Wang, Mengcheng Luo

Frontiers in Genetics

DOI

2022

SCF ubiquitin E3 ligase regulates DNA double-strand breaks in early meiotic recombination

Yong-Juan Guan, Huijuan Lin, N. Leu, G. Ruthel, S. Fuchs, L. Busino, Mengcheng Luo, P. Wang

Nucleic Acids Research

DOI

2022

Histone methyltransferase DOT1L is essential for self-renewal of germline stem cells

Hui-Juan Lin, K. Cheng, H. Kubota, Y. Lan, Simone S. Riedel, Kazue Kakiuchi, Kotaro Sasaki, K. Bernt, M. Bartolomei, Mengcheng Luo, P. Wang

Genes & Development

DOI

2022

Bi-allelic variants in SHOC1 cause non-obstructive azoospermia with meiosis arrest in humans and mice.

Weili Wang, L. Meng, Jiaxin He, Lilan Su, Yong Li, C. Tan, Xi-Lin Xu, H. Nie, Huan Zhang, Juan Du, G. Lu, Mengcheng Luo, G. Lin, C. Tu, Yue-Qiu Tan

Molecular human reproduction

DOI

2021

代谢组学预测人卵母细胞质量与胚胎体外发育潜能的研究现状

曹羽明，张元珍，罗孟成

《生殖医学杂志》

2021

YTHDF1 promotes mRNA degradation via YTHDF1‐AGO2 interaction and phase separation

Jiong Li, Ke Chen, Xin Dong, Yating Xu, Qi Sun, Honghong Wang, Zhen Chen, Cong Liu, Rong Liu, Zhe Yang, Xiangfei Mei, Rongyu Zhang, Liuping Chang, Zongwen Tian, Jianjun Chen, Kaiwei Liang, Chunjiang He, Mengcheng Luo

Cell Proliferation

DOI

2021

Chromatin-Associated Protein Sugp2 Involved in mRNA Alternative Splicing During Mouse Spermatogenesis

Junfeng Zhan, Jianbo Li, Yuerong Wu, Panfeng Wu, Ziqi Yu, Peng Lei Cui, Mofan Zhou, Yumin Xu, Tingyu Jin, Ziye Du, Mengcheng Luo, Cong Liu

Frontiers in Veterinary Science

DOI

2021

SYMPK Is Required for Meiosis and Involved in Alternative Splicing in Male Germ Cells

Rui Wu, Junfeng Zhan, Bo Jian Zheng, Zhen Chen, Jianbo Li, Changrong Li, Rong Liu, Xinhua Zhang, Xiaoyan Huang, Mengcheng Luo

Frontiers in Cell and Developmental Biology

DOI

2021

Paternal USP26 mutations raise Klinefelter syndrome risk in the offspring of mice and humans

Chao Liu, Hongbin Liu, Haobo Zhang, Lina Wang, Mengjing Li, Feifei Cai, Xiuge Wang, Li Wang, Ruidan Zhang, Sijie Yang, Wenwen Liu, Yu Liang, Liying Wang, Xiaohui Song, Shizhen Su, Hui Gao, Jing Jiang, Jinsong Li, Mengcheng Luo, Fei Gao, Qi Chen, Wei Li, Zi‐Jiang Chen

The EMBO Journal

DOI

2021

YTHDC2 is essential for pachytene progression and prevents aberrant microtubule-driven telomere clustering in male meiosis

Rong Liu, Seth D. Kasowitz, D. Homolka, N. Leu, Jordan T. Shaked, G. Ruthel, D. Jain, Huijuan Lin, S. Keeney, Mengcheng Luo, R. Pillai, P. Wang

bioRxiv

DOI

2021

SDX on the X chromosome is required for male sex determination

Junfeng Zhan, Peng Cui, Ziqi Yu, Wei Qu, Mengcheng Luo

Cell Research

DOI

2020

mRBPome capture identifies the RNA-binding protein TRIM71, an essential regulator of spermatogonial differentiation

Guihua Du, Xinrui Wang, Mengcheng Luo, Weiya Xu, Tao Zhou, Mei Wang, Luping Yu, Lufan Li, Li'e Cai, P. Jeremy Wang, John Zhong Li, Jon M. Oatley, Xin Wu

Development

DOI

2020

SKP1 drives the prophase I to metaphase I transition during male meiosis

Yong-Juan Guan, N. Leu, Jun Ma, Lukáš Chmátal, G. Ruthel, Jordana C. Bloom, M. Lampson, J. Schimenti, Mengcheng Luo, P. Wang

Science Advances

DOI

2019

UHRF1 suppresses retrotransposons and cooperates with PRMT5 and PIWI proteins in male germ cells

Juan Dong, Xiaoli Wang, Congcong Cao, Yujiao Wen, Akihiko Sakashita, Si Chen, Jin Zhang, Yue Zhang, Liquan Zhou, Mengcheng Luo, Mingxi Liu, Aihua Liao, Satoshi H. Namekawa, Shuiqiao Yuan

Nature Communications

DOI

2019

Dual functions for the ssDNA-binding protein RPA in meiotic recombination

Bao-Lu Shi, Jiang-Yang Xue, Hao Yin, Rui Guo, Mengcheng Luo, Lan Ye, Qing-Hua Shi, Xiao-Yan Huang, Mingxi Liu, J. Sha, P. Wang

PLoS Genetics

DOI

2019

Biological and RNA regulatory function of MOV10 in mammalian germ cells

Kaiqiang Fu, Suwen Tian, Huanhuan Tan, Caifeng Wang, Hanben Wang, Min Wang, Yuan-Yuan Wang, Zhen Chen, Yan-Feng Wang, Qiuling Yue, Qiushi Xu, Shuya Zhang, Haixin Li, Jie Xie, Mingyan Lin, Mengcheng Luo, F. Chen, Lan Ye, Ke Zheng

BMC Biology

DOI

2017

Embryonic lethality and defective male germ cell development in mice lacking UTF1

Seth D. Kasowitz, Mengcheng Luo, Jun Ma, N. Leu, P. J. Wang

Scientific Reports

DOI

2015

Polycomb Protein SCML2 Associates with USP7 and Counteracts Histone H2A Ubiquitination in the XY Chromatin during Male Meiosis

Mengcheng Luo, Jian Zhou, N. Leu, Carla M. C. Abreu, Jianle Wang, Montserrat C. Anguera, D. de Rooij, M. Jasin, P. Wang

PLoS Genetics

DOI

2013

MEIOB exhibits single-stranded DNA-binding and exonuclease activities and is essential for meiotic recombination

Mengcheng Luo, Fang Yang, N. Leu, Jessica Landaiche, M. Handel, R. Benavente, S. La Salle, P. Wang

Nature Communications

DOI

罗孟成

精选作品

期刊论文

DAXX governs the silencing of LINE1 during spermatogenesis in mice

Ubap2基因敲除对小鼠精子发生及生育能力的影响

Loss of TEX30 leads to male subfertility in mice.

New feature of hMEIOB and hSPATA22 binding to ssDNA from a single-molecule perspective

Microfluidic thermotaxic selection of highly motile sperm and in vitro fertilization

PWWP3A deficiency accelerates testicular senescence in aged mice

Berberine alters the gut microbiota metabolism and impairs spermatogenesis

Editorial: Mammalian spermatogenesis: genetic and environmental factors

The DOT1L-MLLT10 complex regulates male fertility and promotes histone removal during spermiogenesis.

MicroRNA‐202 safeguards meiotic progression by preventing premature SEPARASE‐mediated REC8 cleavage

Identification and characterization of BEND2 as a key regulator of meiosis during mouse spermatogenesis

Fbxw17 is dispensable for viability and fertility in mice

Editorial: Reproductive genomics

SCF ubiquitin E3 ligase regulates DNA double-strand breaks in early meiotic recombination

Histone methyltransferase DOT1L is essential for self-renewal of germline stem cells

Bi-allelic variants in SHOC1 cause non-obstructive azoospermia with meiosis arrest in humans and mice.

代谢组学预测人卵母细胞质量与胚胎体外发育潜能的研究现状

YTHDF1 promotes mRNA degradation via YTHDF1‐AGO2 interaction and phase separation

Chromatin-Associated Protein Sugp2 Involved in mRNA Alternative Splicing During Mouse Spermatogenesis

SYMPK Is Required for Meiosis and Involved in Alternative Splicing in Male Germ Cells

Paternal USP26 mutations raise Klinefelter syndrome risk in the offspring of mice and humans

YTHDC2 is essential for pachytene progression and prevents aberrant microtubule-driven telomere clustering in male meiosis

SDX on the X chromosome is required for male sex determination

mRBPome capture identifies the RNA-binding protein TRIM71, an essential regulator of spermatogonial differentiation

SKP1 drives the prophase I to metaphase I transition during male meiosis

UHRF1 suppresses retrotransposons and cooperates with PRMT5 and PIWI proteins in male germ cells

Dual functions for the ssDNA-binding protein RPA in meiotic recombination

Biological and RNA regulatory function of MOV10 in mammalian germ cells

Embryonic lethality and defective male germ cell development in mice lacking UTF1

Polycomb Protein SCML2 Associates with USP7 and Counteracts Histone H2A Ubiquitination in the XY Chromatin during Male Meiosis

MEIOB exhibits single-stranded DNA-binding and exonuclease activities and is essential for meiotic recombination

会议论文

Skp1在小鼠生殖细胞减数分裂过程中的功能研究

预印本

A commensal anellovirus is associated with asthenozoospermia and induces testicular inflammation in mice

研究方向