百晓学者学者目录

尹莉芳

教授、研究员，中国药科大学

精选作品

期刊论文

2026

盐酸伊伐布雷定缓释制剂中两特定杂质的检测方法探究

季萌，姚彦蓉，李佳荣，朱琼，郑忠辉，冀新雨，付晓哲，王宜运，杭太俊，尹莉芳

《药学与临床研究》

2026

Baiting-enhanced extravasation of lipid nanoparticles for targeted co-delivery of decitabine and siTNF-α to the bone marrow niche in leukemia therapy.

Ying Zhu, Qiushi Li, Yong Zhou, Di Wu, Huanyu Qin, Jinyu Dai, Yifu Lyu, Lei Yang, X. Xin, Lifang Yin

Journal of Controlled Release

DOI

2026

Blood-Brain Barrier-Permeable siRNA Nanodrugs With Dual-Gene Knockdown for Alzheimer's Disease Therapy.

Feng Su, Sheng Lu, Yao-Yao Zhang, Yu Zhang, Lingxuan Cheng, Jing Li, Jun-Lin Zhang, Ying Li, Yun-Gen Xu, Guang-Wei He, Lifang Yin

Clinical and Experimental Pharmacology and Physiology

DOI

2026

A mucin-integrated probiotic hydrogel microsphere for prophylactic gut modulation and Sepsis mitigation

Taiyu Liu, Jing-Jing Li, Wenqing Li, Yue Du, Wenyan Zhang, Fanyu Qian, Ziyue Wang, Xiao-Ning Wang, Lisha Liu, Lifang Yin

Chemical Engineering Journal

DOI

2026

The PAH-AM-PEG-ApoE@siRNA Nanocarrier Delivery System for Polo-like Kinase 1 Inhibition Suppresses Glioma Progression

Feng Su, Shengnan Lu, Jun-Li Zhang, Yu Zhang, Yao-Yao Zhang, Ling Cheng, Jing Li, Ying Li, Guang-Wei He, Lifang Yin

AAPS PharmSciTech

DOI

2026

Co-delivery of a STING agonist and indoleamine 2,3-dioxygenase 1 blockade activates type I dendritic cells in cancer.

Yan-Ming Xia, Li-Xin Hu, Yuhan Hu, Shihao Wang, Qingqing Xiong, Xiao-Hu Wang, Yi-Qun Li, Lifang Yin, Jian Wang, Su-Xin Li

Journal of Controlled Release

DOI

2026

Intranasal biomimetic vesicle platform reprograms the glioblastoma microenvironment for enhanced immunotherapy

Shuo Li, Chao Qin, F. Qian, Jin-Hao Wang, Xianggui Wu, Wen-Qing Li, Tai-Yu Liu, Zhaojie Chen, Beiyuan Zhang, Qi-Yue Liu, Li-Sha Liu, Lifang Yin

Chemical Engineering Journal

DOI

2026

Nanoengineering of STING-IDO1 feedback machinery potentiates antitumor immunity

Yan-Ming Xia, Li-Xin Hu, Xiao-Hu Wang, Mingxi Li, Bo Shi, Siqi Zhu, Yutong Wu, Shu-Ting Xiang, Lifang Yin, Su-Xin Li

Chemical Engineering Journal

DOI

2026

A Dual Glutathione-Depleting Nanoparticle Loaded with Porcine Pancreatic Elastase for Neoadjuvant Chemotherapy of Triple Negative Breast Cancer.

Yan-Ming Xia, Shuxian Xu, Yutong Wu, Xiao-Chen Ma, Linxiu Peng, Yan Lu, Xiaopeng Han, Chao Qin, Lifang Yin

ACS Nano

DOI

2026

Structure-Activity-Driven Multicompartment Lipid Nanoparticles for Synergistic mRNA and siRNA Codelivery in Acute Myeloid Leukemia.

X. Xin, Yifu Lyu, Huanyu Qin, Jinyu Dai, Di Wu, Yu Ding, Qiang Tian, Chao Qin, Na Li, Lifang Yin

Journal of the American Chemical Society

DOI

2026

In situ formation of chylomicron-incorporated lipid nanoparticle via muramyl dipeptide conjugation potentiates lymphatic transport of chemoimmunotherapeutic for leukemia therapy

Pengbo Zhao, Yu Ding, Yinyin Yuan, Huanyu Qin, Jinyu Dai, Di Wu, Zhenduo Duan, Lihui Xin, Luojuan Hu, Sifei Han, X. Xin, Lifang Yin

Chemical Engineering Journal

DOI

2025

还原响应型纳米粒通过双重机制逆转非小细胞肺癌多药耐药性的研究

朱峰，傅超婷，王亚洲，匡正，尹莉芳

《中国药科大学学报》

2025

盐酸伊伐布雷定有关物质的二维液相色谱-质谱联用分析

金雅文，朱琼，郑忠辉，钞瑞瑞，练洵羽，李福享，王宜运，杭太俊，尹莉芳

《药物分析杂志》

DOI

2025

还原响应型载药纳米粒的处方筛选及质量评价研究

朱峰，傅超婷，叶香伶，尹莉芳

《中南药学》

2025

癌相关成纤维细胞和肿瘤细胞之间代谢串扰机制及其在肿瘤治疗中的研究进展

魏琴，尹莉芳，秦超

《中南药学》

2025

长效注射剂的改良与创新：现状与未来

张汶彦，胡鑫蕾，刘莉莎，杨磊，尹莉芳

《药学进展》

DOI

2025

Novel Small-Molecule Treatment and Emerging Biological Therapy for Psoriasis

Yuanyuan Li, Yiheng Cheng, Yuchen Cai, Zhenduo Duan, Hong Xu, Yunan Huang, Xiaonan Ma, X. Xin, Lifang Yin

Biomedicines

DOI

2025

Catch-to-Amplify Nanoparticles with Bacteria Surface for Sequential Mucosal Immune Activation for Acute Myeloid Leukemia Therapy.

X. Xin, Di Wu, Pengbo Zhao, Yuanyuan Li, Huanyu Qin, Jinyu Dai, Yong Zhou, Yifu Lyu, Yang Yang, Ying Zhu, Hang Shi, Lei Yang, Lifang Yin

ACS Nano

DOI

2025

Notch1 siRNA and AMD3100 Ameliorate Metabolic Dysfunction-Associated Steatotic Liver Disease

Chun-Li Zhu, Yiheng Cheng, Lei Yang, Yifu Lyu, Jing-Jing Li, Pengbo Zhao, Ying Zhu, X. Xin, Lifang Yin

Biomedicines

DOI

2025

Hybrid prodrug nanoassembly for hypoxia-triggered immunogenic chemotherapy and immune modulation.

Beiyuan Zhang, Chao Qin, Xue Wang, Chuanhong Shen, Shuo Li, Taiyu Liu, Wenqing Li, Zhaojie Chen, Yawen Wang, Lisha Liu, Lifang Yin

Journal of Controlled Release

DOI

2025

Lipoprotein-mimicking nanodiscs for precise glioblastoma therapy and immune microenvironment modulation

Taiyu Liu, Lisha Liu, Dandan Gao, Wenqing Li, Xianggui Wu, Shuo Li, Beiyuan Zhang, Yaohua Liu, Shan Qiao, Meiqing Lou, Lifang Yin, Yunke Bi

Chemical Engineering Journal

DOI

2025

ROS-sensitive dihydroartemisinin prodrug amplify chemo-immunotherapy efficacy of doxorubicin by coordinating robust tumor cell immunogenic cell death and PD-L1 blockade

Xiaopeng Han, Jiayin Li, Fei Li, Zhongyue Yuan, Hao Li, Lei Yang, Yan-ming Xia, Chao Teng, Chao Qin, Lifang Yin

Chinese Chemical Letters

DOI

2025

MOF-Engineered Platelet-Mimicking Nanocarrier-Encapsulated Cascade Enzymes for ROS Scavenging and Anti-Inflammation in Cerebral Ischemia–Reperfusion Injury

Hao Li, Xiaowei Xie, Yu Zhang, Xiaopeng Han, Ting Shi, Jiayin Li, Wan-Yu Chen, Qin Wei, H. Pan, Shuxian Xu, Qiuyu Chen, Lifang Yin, Chao Qin

Pharmaceutics

DOI

2025

Trapping effect of surface deficient cocrystal synergizes with bimetallic nanoparticles against bacterial infection in wounds.

Yan-Ming Xia, Lei Yang, Shuxian Xu, Yun-han Xia, Linxiu Peng, Yutong Wu, Xiaopeng Han, Chao Qin, Su-Xin Li, Lifang Yin

Journal of Colloid and Interface Science

DOI

2025

Self-amplifying tumor-targeting nanoreactor for enhanced Immuno-Ferroptosis therapy in triple-negative breast cancer

Jiayin Li, Ya-Zhou Wang, Hao Li, Zhongyue Yuan, Qin Wei, Lei Yang, Yan-ming Xia, X. Xin, Lisha Liu, Chao Teng, Chao Qin, Xiaopeng Han, Lifang Yin

Chemical Engineering Journal

DOI

2025

Corrigendum to “Doxorubicin delivered by redox-responsive Hyaluronic Acid–Ibuprofen prodrug micelles for treatment of metastatic breast cancer” [Carbohydrate Polymers 245 (2020) 116527]

Zhuodong Chai, Chao Teng, Lei Yang, Lianjie Ren, Zhongyue Yuan, Siyuan Xu, Manman Cheng, Yanmei Wang, Zhen Yan, Chao Qin, Xiaopeng Han, Lifang Yin

Carbohydrate Polymers

DOI

2024

注射用原位凝胶的分类与基质材料

蒋元，严真，杨磊，尹莉芳

《药学研究》

2024

基于穿透血脑屏障的siRNA纳米递药系统研究进展

苏峰，熊峰，曹俊如，储晓琴，何广卫，尹莉芳

《中国药学杂志》

2024

黄体酮混悬注射剂药动学及体内外相关性研究

刘兰岚，蔡其霖，张汶彦，严真，尹莉芳

《中国药科大学学报》

2024

基因介导的精准免疫疗法在急性髓系白血病治疗中的进展

赵鹏博，朱滢，尹莉芳，辛晓斐

《中国药科大学学报》

2024

Enhanced Antitumor Efficacy of Cytarabine and Idarubicin in Acute Myeloid Leukemia Using Liposomal Formulation: In Vitro and In Vivo Studies

Chun-xia Zhu, Yang Liu, Xiaojun Ji, Yaxuan Si, Xianhao Tao, Xiaohua Zhang, Lifang Yin

Pharmaceutics

DOI

2024

Tenascin C-Guided Nanosystem for Precision Delivery of Obeticholic Acid in Liver Fibrosis Therapy

Yawen Wang, Lei Yang, Qing Xu, Taiyu Liu, Hongliang He, Lisha Liu, Lifang Yin

Pharmaceutics

DOI

2024

A trinity STING-activating nanoparticle harnesses cancer cell STING machinery for enhanced immunotherapy.

Yan-Ming Xia, Bo Shi, Ke-Ke Wang, Li-Xin Hu, Qiran Wang, Shuxian Xu, Xiao-Hu Wang, Pengcheng Xu, Yuan-Bin She, Haitang Xie, Su-Xin Li, Lifang Yin

Journal of Controlled Release

DOI

2024

Lipid nanoparticle-mediated hepatocyte delivery of siRNA and silibinin in metabolic dysfunction-associated steatotic liver disease.

Yifu Lyu, Xiuyi Yang, Lei Yang, Jinyu Dai, Huanyu Qin, Yun-Long Zhou, Yunan Huang, Yanmei Wang, Di Wu, Qindai Shuai, Qilong Li, X. Xin, Lifang Yin

Journal of Controlled Release

DOI

2024

Immune cell-derived extracellular vesicles for precision therapy of inflammatory-related diseases.

Shuo Li, Wenqing Li, Xianggui Wu, Beiyuan Zhang, Lisha Liu, Lifang Yin

Journal of Controlled Release

DOI

2024

Bioresponsive nanocomplex integrating cancer-associated fibroblast deactivation and immunogenic chemotherapy for rebuilding immune-excluded tumors.

Lisha Liu, Beiyuan Zhang, Xianggui Wu, Gang Cheng, Xiao-Peng Han, X. Xin, Chao Qin, Lei Yang, Mei-Rong Huo, Lifang Yin

Nanomedicine: Nanotechnology, Biology and Medicine

DOI

2023

注射用环糊精包合物研究进展

严家瑞，严真，尹莉芳

《药学研究》

DOI

2023

药物纳米晶的制备及其口服转运机制研究进展

吴帅聪，秦超，韩晓鹏，尹莉芳

《药学进展》

2023

调控T细胞代谢在肿瘤免疫治疗中的研究进展

褚欣宇，尹莉芳，秦超

《中南药学》

2023

Disease-specific corona mediated co-delivery of MTX and siRNA-TNFα by a polypeptide nanoplatform with antigen-scavenging functions in psoriasis

X. Xin, Yong Zhou, Yifu Lyu, Ying Zhu, Di Wu, Jing-Jing Li, Chao Qin, Lifang Yin

Journal of Controlled Release

DOI

2023

Synchronous targeted delivery of TGF-β siRNA to stromal and tumor cells elicits robust antitumor immunity against triple-negative breast cancer by comprehensively remodeling the tumor microenvironment

Mengmeng Yang, Chao Qin, Linlin Tao, Gang Cheng, Jingjing Li, Fangnan Lv, Nan Yang, Zuhang Xing, Xinyu Chu, Xiaopeng Han, Meirong Huo, Lifang Yin

Biomaterials

DOI

2023

Topical Delivery of ROS-Responsive Methotrexate Prodrug Nanoassemblies by a Dissolvable Microneedle Patch for Psoriasis Therapy

Yong Zhou, Lei Yang, Yifu Lyu, Di Wu, Ying Zhu, Jingjing Li, Dabo Jiang, Xiaofei Xin, Lifang Yin

International Journal of Nanomedicine

DOI

2023

Self-assembled thioether-bridged paclitaxel-dihydroartemisinin prodrug for amplified antitumor efficacy-based cancer ferroptotic-chemotherapy

Yifei Zheng, Chao Qin, Fei Li, Jingxin Qi, Xinyu Chu, Hao Li, Ting Shi, Zhen Yan, Lei Yang, Xiaofei Xin, Lisha Liu, Xiaopeng Han, Lifang Yin

Biomaterials Science

DOI

2023

ROS-scavenging nanomedicine for “multiple crosstalk” modulation in non-alcoholic fatty liver disease

Xiaofei Xin, Jingjing Li, Wantao Wu, Pengbo Zhao, Yang Yang, Ying Jie Zhu, Lianjie Ren, Chao Qin, Lifang Yin

Biomaterials Science

DOI

2022

非酒精性脂肪性肝病的联合疗法和递送策略

王燕梅，杨磊，辛晓斐，尹莉芳

《中国药科大学学报》

2022

生物药剂学与药物动力学

尹莉芳

《人民卫生出版社》

2022

微球与原位凝胶植入剂长效策略与控制突释的研究进展

肖丽蒙，严真，尹莉芳

《中国药科大学学报》

2022

肿瘤微环境的靶向和重塑策略

杨蒙蒙，韩晓鹏，秦超，杨磊，尹莉芳

《药学学报》

2022

纳米制剂克服肿瘤多药耐药的研究进展

匡正，秦超，杨磊，尹莉芳，韩晓鹏

《药学研究》

2022

基于PBPK模型预测不同晶型利福平的生物等效性

蔡其霖，黎文星，严真，尹莉芳

《中国药科大学学报》

2022

咀嚼片的研发要点及研究进展

孙秉喆，邢嘉萌，严真，尹莉芳

《中南药学》

2022

药物递释系统用于肝纤维化的开发与思考

许青，刘莉莎，杨磊，尹莉芳

《中南药学》

2022

The application of elastin-like peptides in cancer, tissue engineering and ocular disease

Dabo Jiang, Yang Yang, Yang Xiu-yi, Boxuan Wang, Wenxuan Fan, Yuchen Liu, Xiaofei Xin, Lifang Yin

OpenNano

DOI

2022

CXCL10-coronated thermosensitive “stealth” liposomes for sequential chemoimmunotherapy in melanoma

Xiaofei Xin, Yong Zhou, Jingjing Li, Kai Zhang, Chao Qin, Lifang Yin

Nanomedicine Nanotechnology Biology and Medicine

DOI

2021

盐酸伊伐布雷定单层渗透泵控释片的制备与体外释药行为

施沁青，王菁华，程曼曼，尹莉芳，秦超

《中国药科大学学报》

2021

肺动脉高压的药物治疗及药物递送策略

蒋小宏，邢续扬，王孝春，尹莉芳，何伟

《药学学报》

DOI

2021

他克莫司胶囊在健康人体内药动学一致性的预评估

付晓婷，姜净，霍怡彤，宋敏，尹莉芳，杭太俊

《药物分析杂志》

DOI

2021

美沙拉嗪肠溶缓释片的制备与体外释放度考察

赵世娟，严家瑞，史婷，严真，尹莉芳

《药学研究》

DOI

2021

一致性评价中部分品种BCS分类不明确问题的解决方案

张宁，尹莉芳

《药物评价研究》

2021

吸入用瑞德西韦脂质体的制备及其体外评价

赵笛，李菁菁，张凯，秦超，杨磊，尹莉芳

《中国药科大学学报》

2021

Delivery strategies of amphotericin B for invasive fungal infections

Xiaochun Wang, Imran Shair Mohammad, Lifang Fan, Zongmin Zhao, Md Nurunnabi, Marwa A.Sallam, Jun Wu, Zhongjian Chen, Lifang Yin, Wei He

Acta Pharmaceutica Sinica B

2021

Cytosolic delivery of the immunological adjuvant Poly I:C and cytotoxic drug crystals via a carrier-free strategy significantly amplifies immune response

Xiaoqing Du, Yuqi Hou, Jia Huang, Yan Pang, Chenlu Ruan, Wei Wu, Chenjie Xu, Hongwei Zhang, Lifang Yin, Wei He

Acta Pharmaceutica Sinica B

DOI

2021

沙库巴曲缬沙坦钠缓释片的制备与释药机制研究

程曼曼，施沁青，王菁华，尹莉芳，秦超，韩晓鹏

《中南药学》

2021

大分子药物透皮递送策略研究进展

王菁华，程曼曼，施沁青，尹莉芳，秦超

《中南药学》

2021

Dual Targeting of Cancer Cells and MMPs with Self-Assembly Hybrid Nanoparticles for Combination Therapy in Combating Cancer

Kai Zhang, Jingjing Li, Xiaofei Xin, Xiaoqing Du, Di Zhao, Chao Qin, Xiaopeng Han, Meirong Huo, Lei Yang, Lifang Yin

Pharmaceutics

DOI

2021

Cocrystallization-like strategy for the codelivery of hydrophobic and hydrophilic drugs in a single carrier material formulation

Yi Li, Chao Teng, Helena S. Azevedo, Lifang Yin, Wei He

Chinese Chemical Letters

DOI

2021

Resolving hepatic fibrosis via suppressing oxidative stress and an inflammatory response using a novel hyaluronic acid modified nanocomplex

Lianjie Ren, Jingjing Li, Lisha Liu, Wantao Wu, Di Zhao, Kai Zhang, Xiaofei Xin, Lei Yang, Lifang Yin

Biomaterials Science

DOI

2020

动脉粥样硬化疫苗的研究进展

林宸诗，陈玉红，尹莉芳

《中国药科大学学报》

2020

siRNA吸入给药系统的研究进展

周勇，赵笛，杨磊，尹莉芳

《中国医药工业杂志》

DOI

2020

无机纳米材料在药物递送中的研究进展

周叶舒，王燕梅，张倍源，吴帅聪，杨磊，尹莉芳

《中国药科大学学报》

2020

布洛芬速释-缓释双层片的制备及体内药动学研究

贾璐瑶，赵世娟，时云龙，蒋小宏，杨磊，尹莉芳

《中国新药杂志》

2020

Doxorubicin delivered by redox-responsive Hyaluronic Acid–Ibuprofen prodrug micelles for treatment of metastatic breast cancer

Zhuodong Chai, Chao Teng, Lei Yang, Lianjie Ren, Zhongyue Yuan, Siyuan Xu, Manman Cheng, Yanmei Wang, Zhen Yan, Chao Qin, Xiaopeng Han, Lifang Yin

Carbohydrate Polymers

DOI

2020

Fibroblast activation protein-α-adaptive micelles deliver anti-cancer drugs and reprogram stroma fibrosis

Chao Teng, Beiyuan Zhang, Zhongyue Yuan, Zheng Kuang, Zhuodong Chai, Lianjie Ren, Chao Qin, Lei Yang, Xiaopeng Han, Lifang Yin

Nanoscale

DOI

2020

Insight on Multidrug Resistance and Nanomedicine Approaches to Overcome MDR

Imran Shair Mohammad, Wei He, Lifang Yin

Critical Reviews in Therapeutic Drug Carrier Systems

DOI

2019

普瑞巴林微孔渗透泵片的制备及体外评价

祝玲，秦超，吴金莲，陈玉红，尹莉芳

《中国药科大学学报》

2019

硝苯地平骨架缓释片的处方研究

余波，赵笛，严真，阮晨露，赵世娟，尹莉芳

《海峡药学》

2019

Desirable PEGylation for improving tumor selectivity of hyaluronic acid-based nanoparticles via low hepatic captured, long circulation times and CD44 receptor-mediated tumor targeting

Chao Teng, Zhuodong Chai, Zhongyue Yuan, Lianjie Ren, Chenshi Lin, Zhen Yan, Wei He, Chao Qin, Lei Yang, Xiaopeng Han, Lifang Yin

Nanomedicine Nanotechnology Biology and Medicine

DOI

2019

Preparation and evaluation of orally disintegrating film containing donepezil for Alzheimer disease

Xiaopeng Han, Jia-Chen Yan, Lianjie Ren, Minli Xue, Zhongyue Yuan, Tingting Wang, Zhen Yan, Lifang Yin, Lei Yang, Chao Qin

Journal of Drug Delivery Science and Technology

DOI

2019

Drug Nanorod-Mediated Intracellular Delivery of microRNA-101 for Self-sensitization via Autophagy Inhibition

Xiaofei Xin, Xiaoqing Du, Qingqing Xiao, Helena S. Azevedo, Wei He, Lifang Yin

Nano-Micro Letters

DOI

2019

Potent delivery of an MMP inhibitor to the tumor microenvironment with thermosensitive liposomes for the suppression of metastasis and angiogenesis

Yaqi Lyu, Qingqing Xiao, Lifang Yin, Lei Yang, Wei He

Signal Transduction and Targeted Therapy

DOI

2019

“Locked” cancer cells are more sensitive to chemotherapy

Yaqi Lyu, Qingqing Xiao, Yi Li, Yubing Wu, Wei He, Lifang Yin

Bioengineering & Translational Medicine

DOI

2019

ROS-Responsive Polymeric Micelles for Triggered Simultaneous Delivery of PLK1 Inhibitor/miR-34a and Effective Synergistic Therapy in Pancreatic Cancer

Xiaofei Xin, Feng Lin, Qiyue Wang, Lifang Yin, Ram I. Mahato

ACS Applied Materials & Interfaces

DOI

2019

Drug nanocrystals: Fabrication methods and promising therapeutic applications

Imran Shair Mohammad, Haiyan Hu, Lifang Yin, Wei He

International Journal of Pharmaceutics

DOI

2019

Sustained Release Bilayer Tablet of Ibuprofen and Phenylephrine Hydrochloride: Preparation and Pharmacokinetics in Beagle Dogs

Chunli Zhu, Siyuan Xu, Xiaopeng Han, Wei Wang, Wei He, Lifang Yin, Lei Yang, Chao Qin

AAPS PharmSciTech

DOI

2018

聚维酮和共聚维酮为载体的硝苯地平渗透泵片的制备

张继睿，董阳雨，韩清，秦超，尹莉芳

《药学研究》

2018

枸橼酸西地那非掩味树脂复合物的制备及评价

张珊，董阳雨，韩晓鹏，秦超，尹莉芳

《中国新药杂志》

2018

硝苯地平控释包芯片的制备与体外释放度考察

何昀，贾璐瑶，周勇，严真，杨磊，尹莉芳，YU Bo

《海峡药学》

2018

普瑞巴林胃滞留缓释片的制备及体外释药机理研究

史雯星，尹莉芳，祝玲，陈玉红，石心红

《海峡药学》

2018

Drug-delivering-drug approach-based codelivery of paclitaxel and disulfiram for treating multidrug-resistant cancer

Imran Shair Mohammad, Chao Teng, Birendra Chaurasiya, Lifang Yin, Chunyong Wu, Wei He

International Journal of Pharmaceutics

DOI

2018

In vitro and in vivo evaluation of the taste-masking efficiency of Amberlite IRP88 as drug carries in chewable tablets

Xiaopeng Han, Shan Zhang, Zhuodong Chai, Yangyun Dong, Wei He, Lifang Yin, Lei Yang, Chao Qin

Journal of Drug Delivery Science and Technology

DOI

2018

Lipid-bilayer-coated nanogels allow for sustained release and enhanced internalization

Chao Qin, Yaqi Lv, Chaoran Xu, Jingjing Li, Lifang Yin, Wei He

International Journal of Pharmaceutics

DOI

2018

Matrix metalloproteinases sensitive multifunctional micelles for inhibition of metastatic tumor growth and metastasis

Chao Qin, Xin Yang, Yubing Wu, Yaqi Lv, Li Zhang, Xiaofei Xin, Lei Yang, Wei He, Xiaopeng Han, Lifang Yin, Chunyong Wu

Powder Technology

DOI

2018

Amorphous Nanosuspensions Aggregated from Paclitaxel–Hemoglobulin Complexes with Enhanced Cytotoxicity

Chao Qin, Xiaofei Xin, Xue Pei, Lifang Yin, Wei He

Pharmaceutics

DOI

2018

A drug-delivering-drug strategy for combined treatment of metastatic breast cancer

Qingqing Xiao, Xiao Guang Zhu, Yuting Yuan, Lifang Yin, Wei He

Nanomedicine Nanotechnology Biology and Medicine

DOI

2018

Design and optimization of gastro-floating sustained-release tablet of pregabalin: In vitro and in vivo evaluation

Chao Qin, Mengmeng Wu, Siyuan Xu, Xiaowei Wang, Wenxing Shi, Yangyu Dong, Lei Yang, Wei He, Xiaopeng Han, Lifang Yin

International Journal of Pharmaceutics

DOI

2018

A Smart Paclitaxel-Disulfiram Nanococrystals for Efficient MDR Reversal and Enhanced Apoptosis

Imran Shair Mohammad, Wei He, Lifang Yin

Pharmaceutical Research

DOI

2018

Understanding of human ATP binding cassette superfamily and novel multidrug resistance modulators to overcome MDR

Imran Shair Mohammad, Wei He, Lifang Yin

Biomedicine & Pharmacotherapy

DOI

2018

Nanoplatform Assembled from a CD44-Targeted Prodrug and Smart Liposomes for Dual Targeting of Tumor Microenvironment and Cancer Cells

Yaqi Lv, Chaoran Xu, Xiangmei Zhao, Chenshi Lin, Xin Yang, Xiaofei Xin, Li Zhang, Chao Qin, Xiaopeng Han, Lei Yang, Wei He, Lifang Yin

ACS Nano

DOI

2018

Targeting intracellular MMPs efficiently inhibits tumor metastasis and angiogenesis

Yaqi Lv, Xiangmei Zhao, Lidan Zhu, Sijia Li, Qingqing Xiao, Wei He, Lifang Yin

Theranostics

DOI

2018

Drug-delivering-drug platform-mediated potent protein therapeutics via a non-endo-lysosomal route

Xiaofei Xin, Chao Teng, Xiaoqing Du, Yaiqi Lv, Qingqing Xiao, Yubing Wu, Wei He, Lifang Yin

Theranostics

DOI

2017

口腔膜剂的研发与评价

任连杰，刘涓，马骏威，闫佳辰，尹莉芳

《中国中药杂志》

2017

国内外口腔膜剂申报上市进展及其药学评价探讨

任连杰，刘涓，马骏威，闫佳辰，尹莉芳

《药品评价》

2017

[Research & development and evaluation of oral films].

Lianjie Ren, Juan Liu, Jun-Wei Ma, Jia-Chen Yan, Lifang Yin

PubMed

DOI

2017

Rod‐Shaped Active Drug Particles Enable Efficient and Safe Gene Delivery

Xiaofei Xin, Xue Pei, Xin Yang, Yaqi Lv, Li Zhang, Wei He, Lifang Yin

Advanced Science

DOI

2017

Rod‐Shaped Drug Particles for Cancer Therapy: The Importance of Particle Size and Participation of Caveolae Pathway

Wei He, Xiaofei Xin, Yongji Li, Xiaopeng Han, Chao Qin, Lifang Yin

Particle & Particle Systems Characterization

DOI

2017

Cytosolic co-delivery of miRNA-34a and docetaxel with core-shell nanocarriers via caveolae-mediated pathway for the treatment of metastatic breast cancer

Li Zhang, Xin Yang, Yaqi Lv, Xiaofei Xin, Chao Qin, Xiaopeng Han, Lei Yang, Wei He, Lifang Yin

Scientific Reports

DOI

2017

Denatured protein-coated docetaxel nanoparticles: Alterable drug state and cytosolic delivery

Li Zhang, Qingqing Xiao, Yiran Wang, Chenshuang Zhang, Wei He, Lifang Yin

International Journal of Pharmaceutics

DOI

2017

Lactobionic acid-conjugated TPGS nanoparticles for enhancing therapeutic efficacy of etoposide against hepatocellular carcinoma

Altansukh Tsend-Ayush, Xiumei Zhu, Yu Jie Ding, Jianxu Yao, Lifang Yin, Jianping Zhou, Jing Yao

Nanotechnology

DOI

2017

Preparation and evaluation of celecoxib nanosuspensions for bioavailability enhancement

Jia-Li He, Yue Han, Gujun Xu, Lifang Yin, M Ngandeu Neubi, Jianping Zhou, Yang Ding

RSC Advances

DOI

2016

艾拉莫德缓释微丸的研制

施必伟，林巧平，李晓强，许向阳，尹莉芳

《中国医药工业杂志》

2016

高效液相色谱-串联质谱法测定犬血浆中的普瑞巴林及在药代动力学中的应用

王瑜，仲云熙，金孝亮，谷世寅，彭英，尹莉芳，贾元威，孙建国，王广基

《中国临床药理学与治疗学》

2016

他克莫司固体分散体的制备及肠吸收研究

顾念，沈昕怡，秦超，陈金脱，徐思远，尹莉芳

《中国药科大学学报》

2016

药物溶出度仪机械验证标准操作规程

严全鸿，梁超峰，苏朝芬，高玉成，LEE Luke，王晓波，李铮，赵宇，刘鸽，陈日星，章伟光，高建胜，郑如文，左联，陈亭亭，丁梅，罗军，郑兆广，何广卫，朱少璇，陈燕忠，尹莉芳，茅向军，陈悦，周立春，张玉英，王霆

《药学进展》

2016

Denatured protein stabilized drug nanoparticles: tunable drug state and penetration across the intestinal barrier

Wei He, Yiao Wang, Yaqi Lv, Qingqing Xiao, Ling Ye, Bo Cai, Chao Qin, Xiaopeng Han, Ting Cai, Lifang Yin

Journal of Materials Chemistry B

DOI

2016

Core-shell nanocarriers with high paclitaxel loading for passive and active targeting

Jin Zhu, Yaqi Lv, Hui Cao, Jing Yao, Jianping Zhou, Wei He, Lifang Yin

Scientific Reports

DOI

2016

Core–shell nanocarriers with direct cytosolic delivery for tumor targeting

Jin Zhu, Wei He, Yaqi Lv, Hui Cao, Jing Yao, Jianping Zhou, Lifang Yin

Nanomedicine Nanotechnology Biology and Medicine

DOI

2016

Tumor-targeted docetaxel-loaded hyaluronic acid-quercetin polymeric micelles with p-gp inhibitory property for hepatic cancer therapy

Chenfeng Xu, Yu Ding, Ni Jiang, Lifang Yin, Jianping Zhou, Jing Yao

RSC Advances

DOI

2015

致孔剂对拉莫三嗪肠溶缓释片酸介质中释放度的影响

梁福萍，尹莉芳

《中国新药杂志》

2015

一种全新合成的抗抑郁药物的自微乳化载药系统(SMEDDS)理化性质和体外释药行为研究

乌兰，何伟，赵锦花，王国成，尹莉芳

《药学研究》

2015

穿膜肽介导紫杉醇脂质体对肿瘤的治疗作用

赵海伟，何伟，尹莉芳

《药学研究》

2015

Denatured globular protein and bile salt-coated nanoparticles for poorly water-soluble drugs: Penetration across the intestinal epithelial barrier into the circulation system and enhanced oral bioavailability

Wei He, Ke Yang, Lifang Fan, Yaqi Lv, Jin Zhu, Shumin Zhu, Chao Qin, Yiao Wang, Lifang Yin

International Journal of Pharmaceutics

DOI

2015

Self-assembled nanoparticles from hyaluronic acid–paclitaxel prodrugs for direct cytosolic delivery and enhanced antitumor activity

Chaoran Xu, Wei He, Yaqi Lv, Chao Qin, Lingjia Shen, Lifang Yin

International Journal of Pharmaceutics

DOI

2015

Novel drug delivery liposomes targeted with a fully human anti-VEGF165 monoclonal antibody show superior antitumor efficacy in vivo

Chenyang Shi, Hui Cao, Wei He, Fei Gao, Yu Liu, Lifang Yin

Biomedicine & Pharmacotherapy

DOI

2015

Globular Protein-Coated Paclitaxel Nanosuspensions: Interaction Mechanism, Direct Cytosolic Delivery, and Significant Improvement in Pharmacokinetics

Yongji Li, Zhannan Wu, Wei He, Chao Qin, Jing Yao, Jianping Zhou, Lifang Yin

Molecular Pharmaceutics

DOI

2015

Core–shell structured gel-nanocarriers for sustained drug release and enhanced antitumor effect

Wei He, Yaqi Lv, Yaping Zhao, Chaoran Xu, Jin Zhu, Chao Qin, Lifang Yin

International Journal of Pharmaceutics

DOI

2015

A Self-microemulsifying Drug Delivery System (SMEDDS) for a Novel Medicative Compound Against Depression: a Preparation and Bioavailability Study in Rats

Lan Wu, Yanli Qiao, Lina Wang, Jiahua Guo, Guocheng Wang, Wei He, Lifang Yin, Jinhua Zhao

AAPS PharmSciTech

DOI

2015

Redox-sensitive hyaluronic acid–paclitaxel conjugate micelles with high physical drug loading for efficient tumor therapy

Tingjie Yin, Jing Wang, Lifang Yin, Linjia Shen, Jianping Zhou, Meirong Huo

Polymer Chemistry

DOI

2014

Shell-crosslinked hybrid nanoparticles for direct cytosolic delivery for tumor therapy

Wei He, Jin Zhu, Yaqi Lv, Hui Cao, Jing Yao, Jianping Zhou, Lifang Yin

International Journal of Pharmaceutics

DOI

2014

Matrix tablets for sustained release of repaglinide: Preparation, pharmacokinetics and hypoglycemic activity in beagle dogs

Wei He, Mengmeng Wu, Shiqing Huang, Lifang Yin

International Journal of Pharmaceutics

DOI

2014

Bilayer Matrix Tablets for Prolonged Actions of Metformin Hydrochloride and Repaglinide

Wei He, Shi-Jing Huang, Chun-Yan Zhou, Lin Cao, Jing Yao, Jianping Zhou, Guangji Wang, Lifang Yin

AAPS PharmSciTech

DOI

2014

Gastro-floating bilayer tablets for the sustained release of metformin and immediate release of pioglitazone: Preparation and in vitro/in vivo evaluation

Wei He, Yongji Li, Rao Zhang, Zhannan Wu, Lifang Yin

International Journal of Pharmaceutics

DOI

2014

The impact of a chlorotoxin-modified liposome system on receptor MMP-2 and the receptor-associated protein ClC-3

Chao Qin, Bing He, Wenbing Dai, Zhiqiang Lin, Hua Zhang, Xueqing Wang, Jiancheng Wang, Xuan Zhang, Guangji Wang, Lifang Yin, Qiang Zhang

Biomaterials

DOI

2014

Controlled release of metformin hydrochloride and repaglinide from sandwiched osmotic pump tablet

Chao Qin, Wei He, Chunli Zhu, Mengmeng Wu, Jin Zhu, Qiang Zhang, Guangji Wang, Lifang Yin

International Journal of Pharmaceutics

DOI

2014

Inhibition of Metastatic Tumor Growth and Metastasis via Targeting Metastatic Breast Cancer by Chlorotoxin-Modified Liposomes

Chao Qin, Bing He, Wenbing Dai, Hua Zhang, Xueqing Wang, Jiancheng Wang, Xuan Zhang, Guangji Wang, Lifang Yin, Qiang Zhang

Molecular Pharmaceutics

DOI

2013

使用亲水性聚合物调节硝苯地平从缓释骨架片中的释放(英文)

达第，吕雅琪，赵海伟，武占楠，尹莉芳，唐鹤松

《药学研究》

2013

复方盐酸吡格列酮/盐酸二甲双胍控释片的制备及体外释放考察

张尧，李永吉，刘平，武占楠，尹莉芳

《药学与临床研究》

2013

Gastro-floating tablets of cephalexin: Preparation and in vitro/in vivo evaluation

Lifang Yin, Chao Qin, Kaisheng Chen, Chunli Zhu, Hui Cao, Jianping Zhou, Wei He, Qiang Zhang

International Journal of Pharmaceutics

DOI

2013

Simultaneous Determination and Pharmacokinetic Study of Metformin and Pioglitazone in Dog Plasma by LC-MS-MS

Xiaolan Zhang, Yue Peng, P. Wan, Lifang Yin, G. Wang, Jianguo Sun

Journal of Chromatographic Science

DOI

2012

烟酸缓释微丸的制备及体外释放度考察

陈金脱，尹莉芳，周建平

《中国新药杂志》

2012

复方烟酸辛伐他汀双层缓释片的制备及Beagle犬体内药代动力学

周莉，黎洪，尹莉芳，王莎，陈西敬

《中国药科大学学报》

2012

抗体介导的免疫脂质体的研究进展

宋婷，李伟硕，黄维，钱康，包围，尹莉芳

《药学与临床研究》

2012

烟酸缓释胶囊在Beagle犬体内的药动学及生物等效性

王宇成，尹莉芳，陈金脱，陈西敬，周建平

《安徽医药》

2012

In vitroandin vivostudies on a novel solid dispersion of repaglinide using polyvinylpyrrolidone as the carrier

Lifang Yin, Shi-Jing Huang, Chunli Zhu, Shu-Hui Zhang, Qiang Zhang, Xijing Chen, Qing-Wang Liu

Drug Development and Industrial Pharmacy

DOI

2011

盐酸二甲双胍缓释微丸的制备及体外释放度考察

秦超，尹莉芳，王广基，许红，周建平

《中国新药杂志》

2010

水飞蓟素缓释片的制备与处方优化

尹莉芳，黄师婧，王霄旸，张陆勇

《中国药科大学学报》

2010

盐酸普罗帕酮β-CD包合物缓释片的制备及体外释放度的研究

尹莉芳，耿文君，周建平，朱春莉，张陆勇

《中国新药杂志》

2010

热敏脂质体的研究进展

孙飞，尹莉芳，周建平

《药学进展》

2010

In vitro and in vivo evaluation of levofloxacin sustained-release capsules

Lifang Yin, Shi-Jing Huang, Shuguang Jiang, Chunjie Zhao, Zhi-Qiang Pei, Qiang Zhang

Drug Development and Industrial Pharmacy

DOI

2009

盐酸普罗帕酮包合物的制备及其性质研究

耿文君，尹莉芳，周建平，张陆勇

《中国新药杂志》

2009

头孢氨苄生物黏附缓释片的制备及体外评价

张银龙，尹莉芳，周建平，张陆勇

《药学进展》

2008

氧氟沙星缓释微丸的研制

裴志强，尹莉芳，周建平，赵存婕

《中国医院药学杂志》

2008

氧化苦参碱生物黏附缓释片在Beagle犬体内的药动学

尹莉芳，王广基，张陆勇，赵存婕，周建平

《中国药科大学学报》

2008

Box-Behnken中心组合设计优化甘草酸二铵缓释片的处方

马伟，尹莉芳，周建平，赵存婕

《中草药》

2008

薄膜包衣对头孢氨苄胃内漂浮片的影响

尹莉芳，程开生，王广基，张陆勇，臧洪梅，周建平

《中国药科大学学报》

2008

没食子结肠定位胶囊体内靶向性研究

薛梅，高晓黎，斯拉甫，尚靖，尹莉芳，程开生

《亚太传统医药》

2007

中心复合设计法优化氧化苦参碱生物黏附缓释片处方

赵存婕，尹莉芳，周建平，马伟

《中国医院药学杂志》

2007

盐酸左氧氟沙星缓释片的体外释放度及其在犬体内的药动学

李文平，尹莉芳，赵存婕，江振洲，张陆勇，陈矛，叶放，方毓新

《中国新药杂志》

2007

盐酸达克罗宁胶浆剂的制备及含量测定

方少琳，尹莉芳

《海峡药学》

2005

苦参素胃内滞留缓释片的研制及犬体内生物利用度研究

尹莉芳，贺敦伟，王霄旸，张陆勇，江振洲

《中国新药杂志》

2005

苦参素注射液在犬体内的药动学过程

贺敦伟，尹莉芳，张陆勇，江振洲

《中国医院药学杂志》

2005

头孢克洛缓释片的研制及人体药物动力学研究

尹莉芳，屠锡德，徐伟

《中国医药工业杂志》

2005

泮托拉唑肠溶胶囊在犬体内的药动学及生物利用度研究

贺敦伟，尹莉芳，张陆勇，江振洲

《中国药学杂志》

2005

美洛昔康凝胶剂的制备

尹莉芳，徐伟，陈光

《中国医院药学杂志》

会议论文

2018

口服固体制剂一致性评价研究经验分享

尹莉芳

《2018年第十二届中国药物制剂大会》

2018

药物新剂型的研发思路（英文）

尹莉芳

《第十四届中国药学会青年药学论坛》

2017

纳米给药制剂研究进展

尹莉芳

《2017年中国药学大会暨第十七届中国药师周资料汇编》

2015

口服缓释制剂的开发及产业化研究（英文）

尹莉芳

《2015年中国药物制剂大会暨中国药学会药剂专业委员会2015年学术年会暨国际释控协会中国分会2015年学术年会会议论文集》

2013

口服缓释制剂的处方设计及其体内外相关性研究

尹莉芳

Proceedings of BIT's 3rd Annual Symposium of Drug Delivery Systems 2013

2010

盐酸普罗帕酮包合物缓释片的制备及体外释放度的研究

尹莉芳，耿文君，周建平，张陆勇

《2010年中国药学大会暨第十届中国药师周论文集》

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