汪澜

2025

Development and validation of a reporter gene assay for the bioactivity determination of anti-TSLP monoclonal antibodies.

Journal of Pharmaceutical and Biomedical Analysis

DOI

2023

Establishing a novel and sensitive assay for bioactivity determination of anti-CD25 antibodies

Heliyon

DOI

2023

Method validation of a bridging immunoassay in combination with acid-dissociation and bead treatment for detection of anti-drug antibody

Heliyon

DOI

2023

Mass Spectrometry-Based Charge Heterogeneity Characterization of Therapeutic mAbs with Imaged Capillary Isoelectric Focusing and Ion-Exchange Chromatography as Separation Techniques.

Analytical Chemistry

DOI

2023

Development of a novel bispecific antibody GR1801 for rabies

Journal of Medical Virology

DOI

2023

Biparatopic antibody BA7208/7125 effectively neutralizes SARS-CoV-2 variants including Omicron BA.1-BA.5

Cell Discovery

DOI

2023

Comparability strategy and demonstration for post-approval production cell line change of a bevacizumab biosimilar IBI305

Antibody Therapeutics

DOI

2023

To determine the bioactivity of IL‐1β monoclonal antibodies: Introduction of a reliable reporter gene assay

Analytical Science Advances

DOI

2023

Validation of an HPLC-CAD Method for Determination of Lipid Content in LNP-Encapsulated COVID-19 mRNA Vaccines

Vaccines

DOI

2023

Pseudotyped Viruses for Lyssavirus.

Advances in Experimental Medicine and Biology

DOI

2022

Charge Variants Analysis of a Bispecific Antibody Using a Fully Automated One-step Capillary Isoelectric Focusing – Mass Spectrometry Method

Current Pharmaceutical Analysis

DOI

2022

Identification of a monoclonal antibody clipping variant by cross-validation using capillary electrophoresis - sodium dodecyl sulfate, capillary zone electrophoresis - mass spectrometry and capillary isoelectric focusing - mass spectrometry.

Journal of Chromatography A

DOI

2022

Development of a reporter gene assay for antibody dependent cellular cytotoxicity activity determination of anti‐rabies virus glycoprotein antibodies

Microbiology and immunology

DOI

2022

Interlaboratory Co-validation of a UPLC-ToF MS MAM Method for truncations of a Fc Fusion Protein.

Current Pharmaceutical Biotechnology

DOI

2022

Antibody-dependent enhancement (ADE) of SARS-CoV-2 pseudoviral infection requires FcγRIIB and virus-antibody complex with bivalent interaction

Communications Biology

DOI

2022

Fingerprinting trimeric SARS-CoV-2 RBD by capillary isoelectric focusing with whole-column imaging detection

Analytical Biochemistry

DOI

2022

Finger printing human norovirus-like particles by capillary isoelectric focusing with whole column imaging detection.

Virus Research

DOI

2021

Development of a robust bioassay of monoclonal antibodies and biosimilars against TNF-α by NF-κB-inducible lentiviral reporter gene.

International Immunopharmacology

DOI

2021

A robust reporter assay for the determination of the bioactivity of IL-4R-targeted therapeutic antibodies.

Journal of Pharmaceutical and Biomedical Analysis

DOI

2021

Development of a novel reporter gene assay to evaluate antibody-dependent cellular phagocytosis for anti-CD20 therapeutic antibodies.

International Immunopharmacology

DOI

2021

Interlaboratory method validation of capillary electrophoresis sodium dodecyl sulfate (CE‐SDS) methodology for analysis of mAbs

Electrophoresis

DOI

2021

Quality comparability assessment of a SARS-CoV-2-neutralizing antibody across transient, mini-pool-derived and single-clone CHO cells

mAbs

DOI

2021

Development and validation of a reporter gene assay for bioactivity determination of Anti-CGRP monoclonal antibodies.

Analytical Biochemistry

DOI

2021

Structure and function analysis of a potent human neutralizing antibody CA521FALA against SARS-CoV-2

Communications Biology

DOI

2021

A platform method for charge heterogeneity characterization of fusion proteins by icIEF.

Analytical Biochemistry

DOI

2021

A reporter gene assay for determining the biological activity of therapeutic antibodies targeting TIGIT

Acta Pharmaceutica Sinica B

DOI

2021

Development of novel-nanobody-based lateral-flow immunochromatographic strip test for rapid detection of recombinant human interferon α2b

Journal of Pharmaceutical Analysis

DOI

2021

Subvisible Particle Analysis of 17 Monoclonal Antibodies Approved in China Using Flow Imaging and Light Obscuration.

Journal of Pharmacy and Science

DOI

2021

Development and validation of a reporter gene assay to determine the bioactivity of anti-CTLA-4 monoclonal antibodies.

International Immunopharmacology

DOI

2021

Lentil lectin derived from Lens culinaris exhibit broad antiviral activities against SARS-CoV-2 variants

Emerging Microbes and Infections

DOI

2021

Back Cover: Interlaboratory method validation of capillary electrophoresis sodium dodecyl sulfate (CE‐SDS) methodology for analysis of mAbs

Electrophoresis

DOI

2020

Development of an antibody-dependent cellular cytotoxicity reporter assay for measuring anti-Middle East Respiratory Syndrome antibody bioactivity

Scientific Reports

DOI

2020

Analytical Similarity of a Proposed Biosimilar BVZ-BC to Bevacizumab.

Analytical Chemistry

DOI

2020

A robust and stable reporter gene bioassay for anti-IgE antibodies

Analytical and Bioanalytical Chemistry

DOI

2020

A human neutralizing antibody targets the receptor-binding site of SARS-CoV-2

Nature

DOI

2020

Characterization of neutralizing antibody with prophylactic and therapeutic efficacy against SARS-CoV-2 in rhesus monkeys

Nature Communications

DOI

2020

Characterization of a reliable cell-based reporter gene assay for measuring bioactivities of therapeutic anti-interleukin-23 monoclonal antibodies.

International Immunopharmacology

DOI

2020

A Reporter Gene Assay for Measuring the Bioactivity of Anti-LAG-3 Therapeutic Antibodies.

Luminescence (Chichester, England Print)

DOI

2020

Development of a robust reporter gene assay for measuring the bioactivity of OX40-targeted therapeutic antibodies.

Luminescence (Chichester, England Print)

DOI

2019

Antigenic variations of recent street rabies virus

Emerging Microbes and Infections

DOI

2019

均相时间分辨荧光法测定抗PD-1/PD-L1单抗药物活性

DOI

2019

Production of monoclonal antibodies for measuring Avastin and its biosimilar by Sandwich ELISA.

JIM - Journal of Immunological Methods

DOI

2019

A simple and robust reporter gene assay for measuring the bioactivity of anti-RANKL therapeutic antibodies

RSC Advances

DOI

2019

Development of reporter gene assays to determine the bioactivity of biopharmaceuticals.

Biotechnology Advances

DOI

2018

A simple and cost-effective assay for measuring anti-drug antibody in human patients treated with Adalimumab.

JIM - Journal of Immunological Methods

DOI

2018

Front Cover: Interlaboratory method validation of icIEF methodology for analysis of monoclonal antibodies

Electrophoresis

DOI

2018

Development of a robust reporter gene based assay for the bioactivity determination of IL‐5‐targeted therapeutic antibodies

Journal of Pharmaceutical and Biomedical Analysis

DOI

2018

Interlaboratory method validation of icIEF methodology for analysis of monoclonal antibodies

Electrophoresis

DOI

2018

Measuring the bioactivity of anti-IL-6/anti-IL-6R therapeutic antibodies: presentation of a robust reporter gene assay

Analytical and Bioanalytical Chemistry

DOI

2018

LC-MS法对抗PD-1信迪利单抗药物分子铰链区序列改构稳定性的研究

DOI

2017

Erratum: At least two Fc Neu5Gc residues of monoclonal antibodies are required for binding to anti-Neu5Gc antibody

Scientific Reports

DOI

2017

Development of a robust reporter gene assay to measure the bioactivity of anti‐PD‐1/anti‐PD‐L1 therapeutic antibodies

Journal of Pharmaceutical and Biomedical Analysis

DOI

2016

抗体偶联药物抗HER2单抗-MCC-DM1质控方法的建立

2016

At least two Fc Neu5Gc residues of monoclonal antibodies are required for binding to anti-Neu5Gc antibody

Scientific Reports

DOI

2016

3種類のチャイニーズハムスター卵巣細胞蛋白質残基型量検試験キットの比較研究【JST・京大機械翻訳】

2016

組換えウイルス品質管理方法の確立をモノクローナル抗体抗埃博拉【JST・京大機械翻訳】

2016

生物膜干渉技術を応用して治療性モノクローナル抗体と新生児FC受容体の親和力を測定する。【JST・京大機械翻訳】

2016

1種のモノクローナル抗体の理論的消光係数と実験結果の比較を行った。【JST・京大機械翻訳】

2016

ヒト抗血管内皮増殖因子モノクローナル抗体の品質管理法の確立【JST・京大機械翻訳】

2016

脂質組換え型スーパーオキシドジスムターゼの品質研究【JST・京大機械翻訳】

2016

In-depth structural characterization of Kadcyla® (ado-trastuzumab emtansine) and its biosimilar candidate

mAbs

DOI

2016

Development of a robust reporter-based assay for the bioactivity determination of anti-VEGF therapeutic antibodies.

Journal of Pharmaceutical and Biomedical Analysis

DOI

2015

[Development of a novel reporter gene method for determination of ADCC potency of anti-CD20 monoclonal antibody].

Yao xue xue bao = Acta pharmaceutica Sinica

2014

抗体偶联药物抗HER2单抗-MCC-DM1细胞毒活性检测方法的建立及其检测效果评价

2014

Comparative study of size and charge heterogeneities of anti-TNF-αantibodies by high performance liquid chromatography

DOI

2014

[N terminal sequencing for practical detection of monoclonal antibody].

Sheng wu gong cheng xue bao = Chinese journal of biotechnology

2014

Size heterogeneity analysis of monoclonal antibody products

2014

Novaferon, a novel recombinant protein produced by DNA-shuffling of IFN-α, shows antitumor effect in vitro and in vivo

Cancer Cell International

DOI

2014

[Determination of drug antibody ratio in an antibody-drug conjugate].

Yao xue xue bao = Acta pharmaceutica Sinica

2013

Development of a Reference Standard of Escherichia coli DNA for Residual DNA Determination in China

PLoS ONE

DOI

2013

Results of PicoGreen assay for E. coli DNA reference.

DOI

2012

Development and calibration of a standard for the protein content of granulocyte colony-stimulating factor products.

Biologicals (Print)

DOI

2012

Rga exendin assay the biological activity of fusion proteins

2012

RGA (Report Gene Assay) method for detecting biological activity of exendin-4-HAS Byetalog

2012

重组人粒细胞集落刺激因子-Fc融合蛋白（rhG—CSF—Fc）的质量研究

2011

Combined analysis of the association between p73 G4C14-to-A4T14 polymorphisms and cancer risk

Molecular Biology Reports

DOI

2023

Deep learning radiomics for assessment of gastroesophageal varices in people with compensated advanced chronic liver disease

arXiv preprint