周伟伟｜哈尔滨医科大学｜学者主页

百晓学者学者目录

精选作品

期刊论文

2026

TB-YOLO: Automated tumor budding detection in immunohistochemistry slides of colorectal cancer

Weiwei Zhou, Tong Wang, Huai-Yu Zhu, Zeng Yan, Fengyu Cong, Gui-Yang Jiang, Hongming Xu

Biomedical Signal Processing and Control

DOI

2026

Coordinated cellular programmes distinguish responses to neoadjuvant PD-L1 blockade and potentiate combinatorial immunotherapy in ESCC

Si Li, Jiyu Guo, Jianqun Ma, Jiaxin Yang, Zuxiang Wang, Gang Xu, Yun Miao Yu, Kang Xu, Yueying Gao, Weiwei Zhou, Can Zhang, Qinghua Jiang, Xiaoyuan Wang, Hang Yin, Yongsheng Li

Gut

DOI

2025

Artificial intelligence in ADHD: a global perspective on research hotspots, trends and clinical applications

Xiaofang Wang, Qianfang Jia, Lvyuan Liang, Weiwei Zhou, Weihua Yang, Jingfeng Mu

Frontiers In Human Neuroscience，Vol. 19

DOI

2025

Pan-cancer neural regulation pattern with implications for patient stratification and immunotherapy

Yueying Gao, Jiyu Guo, Wenyi Yang, Kefan Liu, Qingyi Yang, Si Li, Dezhong Lv, Yangyang Cai, Kang Xu, Weiwei Zhou, Qinghua Jiang, Juan Xu, Yongsheng Li, Haoxiu Sun

Molecular Therapy — Nucleic Acids

DOI

2025

CellSNVReg: a multidimensional resource for SNV-mediated regulatory perturbations in single-cell and spatial omics

Jingyi Shi, Shiqian Zhang, Zhenglin Lu, Weiwei Zhou, Weijian Lu, Gengdong Chen, Jianing Li, Wenhui Liu, Jiaqi Huang, Tiantongfei Jiang, Xiyun Jin, Juan Xu, Tingting Shao

Nucleic Acids Research

DOI

2025

LncCE: Landscape of Cellularly-elevated lncRNAs in Single Cells Across Normal and Cancer Tissues

Kang Xu, Yujie Liu, Chongwen Lv, Ya Hong Luo, Jingyi Shi, Haozhe Zou, Weiwei Zhou, Dezhong Lv, Changbo Yang, Yongsheng Li, Juan Xu

Genomics Proteomics & Bioinformatics

DOI

2025

SMTdb: A Comprehensive Spatial Meta-Transcriptome Resource in Cancer

Weiwei Zhou, Qingyi Yang, Jiyu Guo, Si Li, Minghai Su, Feng Leng, Tingyu Rong, Jingyi Shi, Yueying Gao, Tiantongfei Jiang, Juan Xu, Yongsheng Li

Molecular Biology and Evolution

DOI

2024

stSNV: a comprehensive resource of SNVs in spatial transcriptome

Changbo Yang, Yujie Liu, Xiaohua Wang, Qing Jia, Yuqi Fan, Zhenglin Lu, Jingyi Shi, Zhaoxin Liu, Gengdong Chen, Jianing Li, Weijian Lu, Weiwei Zhou, Dezhong Lv, Haozhe Zou, Juan Xu, Yongsheng Li, Qinghua Jiang, Tao Wang, Tingting Shao

Nucleic Acids Research

DOI

2024

Cancer Stemness Online: A Resource for Investigating Cancer Stemness and Associations with Immune Response

Weiwei Zhou, Minghai Su, Tiantongfei Jiang, Yunjin Xie, Jingyi Shi, Yingying Ma, Kang Xu, Gang Xu, Yongsheng Li, Juan Xu

Genomics Proteomics & Bioinformatics

DOI

2024

CardioAtlas: deciphering the single-cell transcriptome landscape in cardiovascular tissues and diseases

Tiantongfei Jiang, Xiaoyan Jin, Yueying Gao, Weiwei Zhou, Jinyang Yu, Yongsheng Li, Juan Xu, Benzhi Cai

Biomarker Research

DOI

2024

CanCellVar: A database for single-cell variants map in human cancer

Changbo Yang, Yujie Liu, Chongwen Lv, Mengjia Xu, Kang Xu, Jingyi Shi, Tingting Tan, Weiwei Zhou, Dezhong Lv, Yongsheng Li, Juan Xu, Tingting Shao

The American Journal of Human Genetics

DOI

2023

SORC: an integrated spatial omics resource in cancer

Weiwei Zhou, Minghai Su, Tiantongfei Jiang, Qingyi Yang, Qisen Sun, Kang Xu, Jingyi Shi, Changbo Yang, Na Ding, Yongsheng Li, Juan Xu

Nucleic Acids Research

DOI

2023

Deep immunophenotyping reveals clinically distinct cellular states and ecosystems in large-scale colorectal cancer

Si Li, Tao Pan, Gang Xu, Yueying Gao, Ya Zhang, Qi Xu, Jiwei Pan, Weiwei Zhou, Juan Xu, Qifu Li, Yongsheng Li

Communications Biology

DOI

2023

Single-cell RNA binding protein regulatory network analyses reveal oncogenic HNRNPK-MYC signalling pathway in cancer

Weiwei Zhou, Qiuling Jie, Tao Pan, Jingyi Shi, Tiantongfei Jiang, Ya Zhang, Na Ding, Juan Xu, Yanlin Ma, Yongsheng Li

Communications Biology

DOI

2023

A global database for modeling tumor-immune cell communication

Yunjin Xie, Weiwei Zhou, Jingyi Shi, Mengjia Xu, Zijing Lin, Donghao Li, Jianing Li, Shujun Cheng, Tingting Shao, Juan Xu

Scientific Data

DOI

2023

Prioritizing exhausted T cell marker genes highlights immune subtypes in pan-cancer

Chunlong Zhang, Qi Sheng, Xue Zhang, Kang Xu, Xiaoyan Jin, Weiwei Zhou, Mengying Zhang, Dezhong Lv, Changbo Yang, Yongsheng Li, Juan Xu, Xia Li

iScience

DOI

2022

ImmCluster: an ensemble resource for immunology cell type clustering and annotations in normal and cancerous tissues

Tiantongfei Jiang, Weiwei Zhou, Qi Sheng, Jiaxin Yu, Yunjin Xie, Na Ding, Yunpeng Zhang, Juan Xu, Yongsheng Li

Nucleic Acids Research

DOI

2022

PRES: a webserver for decoding the functional perturbations of RNA editing sites

Dezhong Lv, Kang Xu, Changbo Yang, Yujie Liu, Ya Hong Luo, Weiwei Zhou, Haozhe Zou, Yangyang Cai, Na Ding, Xia Li, Tingting Shao, Yongsheng Li, Juan Xu

Briefings in Bioinformatics

DOI

2022

Shedding light on the hidden human proteome expands immunopeptidome in cancer

Yongsheng Li, Yunpeng Zhang, Tao Pan, Ping Zhou, Weiwei Zhou, Yueying Gao, Shaojiang Zheng, Juan Xu

Briefings in Bioinformatics

DOI

2022

Data analysis guidelines for single-cell RNA-seq in biomedical studies and clinical applications

Min‐Ying Su, Tao Pan, Qiu-Zhen Chen, Weiwei Zhou, Yi Gong, Gang Xu, Huan-Yu Yan, Si Li, Qiao-Zhen Shi, Ya Zhang, Xiao Chun He, Chunjie Jiang, Shicai Fan, Xia Li, Murray J. Cairns, Xi Wang, Yongsheng Li

Military Medical Research

DOI

2022

Long noncoding RNA LINC01132 enhances immunosuppression and therapy resistance via NRF1/DPP4 axis in hepatocellular carcinoma

Jiwei Zhang, Tao Pan, Weiwei Zhou, Ya Zhang, Gang Xu, Qi Xu, Si Li, Yueying Gao, Zhengtao Wang, Juan Xu, Yongsheng Li

Journal of Experimental & Clinical Cancer Research

DOI

2022

Comprehensive characterization of human–virus protein-protein interactions reveals disease comorbidities and potential antiviral drugs

Si Li, Weiwei Zhou, Donghao Li, Tao Pan, Jing Guo, Haozhe Zou, Zhanyu Tian, Kongning Li, Juan Xu, Xia Li, Yongsheng Li

Computational and Structural Biotechnology Journal

DOI

2021

ImmReg: the regulon atlas of immune-related pathways across cancer types

Tiantongfei Jiang, Weiwei Zhou, Zhenghong Chang, Haozhe Zou, Jing Bai, Qisen Sun, Tao Pan, Juan Xu, Yongsheng Li, Xia Li

Nucleic Acids Research

DOI

2021

Alternative splicing perturbation landscape identifies RNA binding proteins as potential therapeutic targets in cancer

Junyi Li, Tao Pan, Liuxin Chen, Qi Wang, Zhenghong Chang, Weiwei Zhou, Xia Li, Xinhui Li, Gang Xu, Yongsheng Li, Xia Li, Yongsheng Li, Yunpeng Zhang

Molecular Therapy — Nucleic Acids

DOI

2020

SurvivalMeth: a web server to investigate the effect of DNA methylation-related functional elements on prognosis

Chunlong Zhang, Ning Zhao, Xue Zhang, Jun Ying Xiao, Junyi Li, Dezhong Lv, Weiwei Zhou, Yongsheng Li, Juan Xu, Xia Li

Briefings in Bioinformatics

DOI

2020

Pan-cancer characterization of immune-related lncRNAs identifies potential oncogenic biomarkers

Yongsheng Li, Tiantongfei Jiang, Weiwei Zhou, Junyi Li, Xia Li, Xinhui Li, Qi Wang, Jiaqi Yin, Jiaqi Yin, Liuxin Chen, Yunpeng Zhang, Juan Xu, Xia Li, Xia Li

Nature Communications

DOI

2020

Complex impact of DNA methylation on transcriptional dysregulation across 22 human cancer types

Zishan Wang, Jiaqi Yin, Weiwei Zhou, Jing Bai, Yunjin Xie, Kang Xu, Xiangyi Zheng, Jun Ying Xiao, Li Zhou, Xiaolin Qi, Yongsheng Li, Xia Li, Juan Xu

Nucleic Acids Research

DOI

预印本

2026

CIGTSurv: Clinical Information Guided Tri-modal Survival Prediction with Local Prototype Association and Global Feature Alignment

Jing Dai, Qibin Zhang, Weiwei Zhou, Mingde Xu, Jingsong Liu, Jingdong Zhang, Hongming Xu

arXiv preprint

2025

Towards Cellular-Scale Interpretability in Pathology Foundation Models for Biomarker Assessment

Jingsong Liu, Han Li, Zhengyang Xu, Franz-Leonard Klaus, Fabian Stögbauer, Shihui Zu, Weiwei Zhou, Atsuko Kasajima, Felix Schicktanz, Alexander Muckenhuber, Julius Shakhtour, Jiale Yu, Tiannan Zheng, Xun Ma, Maggie Wang, Christian Grashei, Bao Li, Guiyang Jiang, Hongming Xu, Shaohua Kevin Zhou, Nassir Navab, Peter J. Schüffler

arXiv preprint

研究方向

生物医学信息学免疫信息学

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