陈文华｜五邑大学｜学者主页

2026

Structure-Based Discovery of JN210 as a Potent Dual DCN1/HDAC Inhibitor for the Treatment of Nonsmall Cell Lung Cancer

Tao Zheng, Yigui Li, Yunyuan Huang, Linchong He, Xiaojie Huang, Cong Fan, Juqi Wen, Jun Xu, Ping-Hua Sun, Wen‐Hua Chen, Xin Chen

Journal of Medicinal Chemistry

DOI

2026

Development of Glycosylated and Dimeric FAP-Targeted Radiotracers for Preclinical Evaluation in FAP-Positive Glioblastoma Models

Tian Jin, L Y H Sun, Chaoquan Lai, Boyu Tan, H B Wu, Longyong Ding, C W, Shimei Jin, Hangzheng Zhou, Guo Q, Yeshan Qin, Chunrong Qu, Wen‐Hua Chen, Zhen Cheng

Journal of Medicinal Chemistry

DOI

2026

A bis(benzimidazolyl)-based anion transporter triggers chloride-initiated pyroptosis of MDA-MB-468 and 4T1 triple-negative breast cancer cells in vitro and in vivo

Li Chen, Haodong Yang, Jinhui Hu, Lanqing Li, Pinghua Sun, Wen‐Hua Chen

Biochemical Pharmacology

DOI

2026

Molecularly engineered solvatochromic fluorescent probes for the recognition of nonalcoholic steatohepatitis and inflammation by the detection of lipid droplet polarity

Jingjie Liang, Lanqing Li, Le Chen, Wen‐Hua Chen

Dyes and Pigments

DOI

2025

Dual Induction of Ferroptosis and Apoptosis by Triazolopyrimidinyl Derivatives: Design, Synthesis, and Biological Evaluation for Their Anticancer Efficacy via Calcium/Calmodulin Signaling and Mitochondrial Impairment

Lian Chen, Zhonghui Lu, Yunfei Hu, Lanqing Li, Jia‐Qiang Wu, Wen‐Hua Chen, Jinhui Hu

Journal of Medicinal Chemistry

DOI

2025

Environmentally sensitive fluorescent probes for the visualization of selective proteins: Recent progress and biomedical applications

Jinhui Hu, Lulu Jiang, Lanqing Li, Wen‐Hua Chen

European Journal of Medicinal Chemistry

DOI

2025

Ferroptosis of Cancer Cells via Tubulin Degradation and Mitochondrial Dysfunction: A Novel Mechanism of Anticancer Effect for Small-Molecule Anion Transporters

Xiao-Qiao Hong, Li Chen, Xi-Hui Yu, Lanqing Li, Jia‐Qiang Wu, Jinhui Hu, Qin-Chao Mao, Wen‐Hua Chen

Journal of Medicinal Chemistry

DOI

2025

Design, synthesis and biological evaluation of Golgi-targeting anion transporters as inducers of Golgiphagy and apoptosis in cancer cells

Haodong Yang, Li Chen, Li Chen, Zixing Jiang, Lanqing Li, Jinhui Hu, Wen‐Hua Chen

European Journal of Medicinal Chemistry

DOI

2025

A novel multi-site and mitochondrial-targeting fluorescent probe for selective recognition of cancer cells and sensing of hypochlorous acid in vivo

Wantao Liao, Chunzheng Wang, Meng Wu, Ruiya Wang, Lanqing Li, Pengjie Chao, Xuanjun Zhang, Jinhui Hu, Wen‐Hua Chen

Microchemical Journal

DOI

2025

Radiosynthesis and Biological Evaluation of a Small-Molecule Probe for Thyroid-Stimulating Hormone Receptor

Yuanyuan Zhou, Ji Tao, Yuanpeng Jiang, Aiyan Ji, Xiangning Luo, Jin Fan Tian, Xuanyan Zhao, Kun Qian, Chunrong Qu, Renfei Wang, Wen‐Hua Chen, Zhen Cheng

ACS Medicinal Chemistry Letters

DOI

2025

A lipid droplets-targeting near-infrared fluorescent probe for the specific imaging of hepatoma cells and the detection of H2S in biological systems

Hu Jingxin, Ruiya Wang, Wantao Liao, Chunzheng Wang, Lanqing Li, Jinhui Hu, Pengjie Chao, Xuanjun Zhang, Wen‐Hua Chen

Microchemical Journal

DOI

2025

A reversible smartphone-based fluorescent probe for the rapid detection of ammonia in biofluids

Ruiya Wang, Chunzheng Wang, Jingxin Hu, Wantao Liao, Lanqing Li, Jinhui Hu, Wen‐Hua Chen

Microchemical Journal

DOI

2025

Extraction Optimization and Bioactivity of Polysaccharides from Ganoderma leucocontextum Spores

Siying Peng, Yanghui Ou, Yali Zhang, Hongliang Yao, Wen‐Hua Chen

Pharmaceuticals

DOI

2024

Design, synthesis and biological evaluation of a 1,2,3-triazolyl-bearing betulinic acid derivatives as α-glucosidase inhibitors

Yufei Zhang, Jingjing Liu, Jiangyi Li, Jinping Sun, Bingwen Liang, Xiaofeng Min, Zhuang Xiong, Wen‐Hua Chen, Xuetao Xu

Journal of Molecular Structure

DOI

2024

An activatable “AIE + ESIPT” fluorescent probe for dual-imaging of lipid droplets and hydrogen peroxide in drug-induced liver injury model

Wantao Liao, Chunzheng Wang, Ruiya Wang, Meng Wu, Lanqing Li, Pengjie Chao, Jinhui Hu, Wen‐Hua Chen

Analytica Chimica Acta

DOI

2024

Rh(III)-Catalyzed, Redox-Neutral, C–H Multifluoroalkenylation of Benzamides

Wen‐Hua Chen, Jun Xu, Jia‐Qiang Wu, Wei Lin, Yifei Qu, Huixuan Zhu, Mei Xie, Jinhui Hu, Zhuang Xiong

Synthesis

DOI

2024

Design, synthesis and biological evaluation of novel betulinic acid derivatives containing 1,2,4-triazole-derived schiff bases as α-glucosidase inhibitors

Yufei Zhang, Xiaoyan Yu, Jiangyi Li, Bingwen Liang, Jinping Sun, Xiaofeng Min, Zhuang Xiong, Wen‐Hua Chen, Xuetao Xu

Journal of Molecular Structure

DOI

2024

Chemical Composition of Essential Oil from Citrus reticulata Blanco cv. Chachiensis (Chachi) and Its Anti-Mosquito Activity against Pyrethroid-Resistant Aedes albopictus

Jifan Cao, Wende Zheng, Baizhong Chen, Zhenping Yan, Xiaowen Tang, Jiahao Li, Zhen Zhang, Song Ang, Chen Li, Rihui Wu, Panpan Wu, Wen‐Hua Chen

Insects

DOI

2024

Anticancer efficacy triggered by synergistically modulating the homeostasis of anions and iron: Design, synthesis and biological evaluation of dual-functional squaramide-hydroxamic acid conjugates

Hai-Tao Zhi, Zhonghui Lu, Li Chen, Jia‐Qiang Wu, Lanqing Li, Jinhui Hu, Wen‐Hua Chen

Bioorganic Chemistry

DOI

2024

1,2,3-Triazole-based betulinic acid derivatives as α-glucosidase inhibitors: Synthesis and in vitro and in vivo biological evaluation

Yufei Zhang, Jiangyi Li, Xiaofeng Min, Bingwen Liang, Jinping Sun, Keyin Lin, Zhuang Xiong, Xuetao Xu, Wen‐Hua Chen

Journal of Molecular Structure

DOI

2024

Study of the Structure and Bioactivity of Polysaccharides from Different Parts of Stemona tuberosa Lour

Xiang Qiu, Yanghui Ou, Shengjia Lu, Yibin Liang, Yali Zhang, Mengjie Li, Gang Li, Hongwei Ma, Yanting Wu, Zhaoyu He, Zhensheng Zhang, Hongliang Yao, Wen‐Hua Chen

Molecules

DOI

2024

A novel donor-acceptor fluorescent probe for the fluorogenic/ chromogenic detection and bioimaging of nitric oxide

Jingxin Hu, Ruiya Wang, Wantao Liao, Jinhui Hu, Lanqing Li, Zhen Cheng, Wen‐Hua Chen

Analytica Chimica Acta

DOI

2024

Identification of sedative-hypnotic compounds shared by five medicinal Polyporales mushrooms using UPLC-Q-TOF-MS/MS-based untargeted metabolomics

Wei Chen, Jun-Wen Yu, Yu-Yi Deng, Lut Yi Wong, Chen Wang, Yu-Ling Liang, Yuk-Tung Leung, Jia-Yi Tian, Ying Wu, Kelvin Sze‐Yin Leung, Jinhui Hu, Wen‐Hua Chen, Xiaobing Dou, Zhi‐Ling Yu, Ying‐Jie Chen, Zhi‐Ling Yu

Phytomedicine

DOI

2024

Recent progress in organelle-targeting fluorescent probes for the detection of peroxynitrite

Lanqing Li, Chunzheng Wang, Jinhui Hu, Wen‐Hua Chen

Chemical Communications

DOI

2023

Design, Synthesis, and Antitumor Efficacy of Substituted 2-Amino[1,2,4]triazolopyrimidines and Related Heterocycles as Dual Inhibitors for Microtubule Polymerization and Janus Kinase 2

Li Chen, Yunfei Hu, Zhonghui Lu, Zeyin Lin, Lanqing Li, Jia‐Qiang Wu, Zhi‐Ling Yu, Chunye Wang, Wen‐Hua Chen, Jinhui Hu

Journal of Medicinal Chemistry

DOI

2023

Identification of 1,3,4-oxadiazolyl-containing β-carboline derivatives as novel α-glucosidase inhibitors with antidiabetic activity

Di Xiao, Li Lu, Bingwen Liang, Zhuang Xiong, Xuetao Xu, Wen‐Hua Chen

European Journal of Medicinal Chemistry

DOI

2023

Divergent synthesis of difluoromethylated indole-3-carbinols, bisindolylmethanes and indole-3-methanamines

Yifei Qu, Xiaojia Cai, Yuzhuang Guan, Jiamin Tan, Zhangping Cai, Minyun Liu, Ya-Si Huang, Jinhui Hu, Wen‐Hua Chen, Jia‐Qiang Wu

Organic & Biomolecular Chemistry

DOI

2023

Combined inhibition of pyruvate dehydrogenase kinase 1 and hexokinase 2 induces apoptsis in non-small cell lung cancer cell models

Yizhen Guo, Xianchen Lu, Yan Zhou, Wen‐Hua Chen, Kin Yip Tam

Experimental Cell Research

DOI

2023

Epigallocatechin gallate circumvents drug‐induced resistance in non‐small‐cell lung cancer by modulating glucose metabolism and AMPK/AKT/MAPK axis

Yan Zhou, Shiqi Huang, Yizhen Guo, Maoxin Ran, Wenying Shan, Wen‐Hua Chen, Kin Yip Tam

Phytotherapy Research

DOI

2023

Carboxymethyl Chitosan/Sodium Alginate/Chitosan Quaternary Ammonium Salt Composite Hydrogel Supported 3J for the Treatment of Oral Ulcer

Tao Lin, Dandan Chen, Yan Geng, Jiayu Li, Yanghui Ou, Zhijun Zeng, Canqiang Yin, Xudong Qian, Xiang Qiu, Gang Li, Yali Zhang, Wen Guan, Mengjie Li, Xiaojia Cai, Jiaqiang Wu, Wen‐Hua Chen, Yan‐Qing Guan, Hongliang Yao

Gels

DOI

2023

Fibroblast Activation Protein Targeting Probe with Gly–Pro Sequence for PET of Glioblastoma

Chaoquan Lai, Rui Cao, Renda Li, Chunfeng He, Xiao Wang, Hui Shi, Chunrong Qu, Kun Qian, Shaoli Song, Wen‐Hua Chen, Zhen Cheng

Molecular Pharmaceutics

DOI

2023

Selenadiazolesbenzothiadiazole‐Based Small Donor–Acceptor–Donor Dye for Photothermal Therapy in NIR‐II Window

Yibin Wu, Aiyan Ji, Hongyue Lou, Ruihu Song, Zhen Cheng, Wen‐Hua Chen, Chunrong Qu

Advanced Therapeutics

DOI

2023

A tri-herb formulation protects against ethanol-induced mouse liver injury and downregulates mitogen-activated protein kinase phosphatase 1

Wei Chen, Yu-Yi Deng, Jun-Wen Yu, Jun-Wen Yu, Yuk-Tung Leung, Jing‐Xuan Bai, Ying‐Jie Chen, Ying Wu, Li Wang, Xiaoqi Wang, Xiao-Qi Wang, Jinhui Hu, Wen‐Hua Chen, Xiaobing Dou, Kelvin Sze‐Yin Leung, Zhi‐Ling Yu, Zhi‐Ling Yu

Phytomedicine

DOI

2023

Ultrasonic assisted extraction, characterization and gut microbiota-dependent anti-obesity effect of polysaccharide from Pericarpium Citri Reticulatae 'Chachiensis'

Yapeng Li, Zi Li, Baizhong Chen, Ya‐Jun Hou, Yilin Wen, Li‐She Gan, Jingwei Jin, Chen Li, Panpan Wu, Dongli Li, Wen‐Hua Chen, Rihui Wu

Ultrasonics Sonochemistry

DOI

2023

Evaluations of the neuroprotective effects of a dual-target isoquinoline inhibitor in the triple transgenic mouse model of Alzheimer's disease

Rong Wei, Junqiu He, Wen‐Hua Chen, Kin Yip Tam

Neuroscience Letters

DOI

2023

Design, Synthesis and Antitumor Activity of Novel Selenium-Containing Tepotinib Derivatives as Dual Inhibitors of c-Met and TrxR

Jinhui Hu, Li Chen, Zhonghui Lu, Han Yao, Yunfei Hu, Luanqi Feng, Yanqing Pang, Jia‐Qiang Wu, Zhi‐Ling Yu, Wen‐Hua Chen

Molecules

DOI

2023

Synthesis of a Golgi-targeting fluorescent probe for the selective detection of chloride anions

Min Yuan, Jinhui Hu, Wen‐Hua Chen

Organic & Biomolecular Chemistry

DOI

2023

Rh( iii )-catalyzed redox-neutral C–H alkenylation of benzamides with gem -difluorohomoallylic silyl ethers via β-H elimination

Xueli Cui, Jing Qu, Jianfeng Yi, Weiqiang Sun, Jinhui Hu, Suqin Guo, Jingwei Jin, Wen‐Hua Chen, Wing‐Leung Wong, Jia‐Qiang Wu

Chemical Communications

DOI

2023

Facile access to 2-hydroxy-2-substituted indole-3-ones via a copper-catalyzed oxidative cyclization of 2-arylethynylanilines

Weiqiang Sun, Xueli Cui, Jing Qu, Xiaojia Cai, Jinhui Hu, Zhuang Xiong, Suqin Guo, Jun Xu, Wen‐Hua Chen, Jia‐Qiang Wu

Chemical Communications

DOI

2022

Recent Advance in the biological activity of synephrine in Citri Reticulatae Pericarpium

Yuechang Huang, Jiamin Li, Baizhong Chen, Xingmin Zhang, Rihui Wu, Panpan Wu, Chen Li, Wen‐Hua Chen

European Journal of Medicinal Chemistry Reports

DOI

2022

Synthesis and mechanism of biological action of morpholinyl-bearing arylsquaramides as small-molecule lysosomal pH modulators

Tao Zhang, Xiao-Qiao Hong, Hai-Tao Zhi, Jinhui Hu, Wen‐Hua Chen

RSC Advances

DOI

2022

Chemical compositions and anti-mosquito activity of essential oils from Pericarpium Citri Reticulataes of different aging years

Jiahao Li, Xiaowen Tang, Baizhong Chen, Wende Zheng, Zhenping Yan, Zhen Zhang, Jinxuan Li, Kaize Su, Song Ang, Rihui Wu, Kun Zhang, Chen Li, Wen‐Hua Chen, Panpan Wu

Industrial Crops and Products

DOI

2022

Access to 3-Amino-[1,2,4]-triazolo Pyridines and Related Heterocycles via Electrochemically Induced Desulfurative Cyclization

Yunfei Hu, Li Chen, Canlin Zou, Jiangtao He, Luanqi Feng, Jia‐Qiang Wu, Wen‐Hua Chen, Jinhui Hu

Organic Letters

DOI

2022

Larvicidal Activity of Two Rutaceae Plant Essential Oils and Their Constituents Against Aedes albopictus (Diptera: Culicidae) in Multiple Formulations

Rongchao Jian, Yuan Lin, Yuling Li, Weifeng Wu, Xiaofei Ren, Zhanyuan Liang, Lingjia Kong, Jinglin Cai, Canyao Lao, Min Wu, Wen‐Hua Chen, Jing Chen, Weiqian David Hong, Zhaojun Sheng

Journal of Medical Entomology

DOI

2022

AIE-based gold nanostar-berberine dimer nanocomposites for PDT and PTT combination therapy toward breast cancer

Rong-Tian Li, Ming Chen, Zi-Chuan Yang, Yongjian Chen, Nai-Han Huang, Wen‐Hua Chen, Jun Chen, Jin-Xiang Chen

Nanoscale

DOI

2022

Synthesis of difluoromethyl carbinols from the Friedel–Crafts reaction of electron-rich arenes with difluorovinyl arylsulfonates

Xiaojia Cai, Jinyuan Xu, Xueli Cui, Jing Qu, Weiqiang Sun, Jinhui Hu, Shuwen Zhao, Wen‐Hua Chen, Hongliang Li, Jia‐Qiang Wu

Organic Chemistry Frontiers

DOI

2021

Design, synthesis and biological evaluation of indole-based [1,2,4]triazolo[4,3-a] pyridine derivatives as novel microtubule polymerization inhibitors

Chengjun Wu, Jia‐Qiang Wu, Yunfei Hu, Suyun Pu, Yuying Lin, Zimai Zeng, Jinhui Hu, Wen‐Hua Chen

European Journal of Medicinal Chemistry

DOI

2021

Synthesis and biological activity of squaramido-tethered bisbenzimidazoles as synthetic anion transporters

Zhong‐Kun Wang, Xiao-Qiao Hong, Jinhui Hu, Yuan-Yuan Xing, Wen‐Hua Chen

RSC Advances

DOI

2021

Anion-Responsive Manganese Porphyrin Facilitates Chloride Transport and Induces Immunogenic Cell Death

Fang‐Xin Wang, Jiewei Liu, Xiao-Qiao Hong, Cai‐Ping Tan, Li Zhang, Wen‐Hua Chen, Peter John Sadler, Zong‐Wan Mao

CCS Chemistry

DOI

2021

Curvature-regulated transmembrane anion transport by a trifluoromethylated bisbenzimidazole

Xiao-Qiao Hong, Yuan-Yuan Xing, Zhong‐Kun Wang, Qin-Chao Mao, Wen‐Hua Chen

Chinese Chemical Letters

DOI

2021

Discovery of benthol A and its challenging stereochemical assignment: opening up a new window for skeletal diversity of super-carbon-chain compounds

Zhongping Jiang, Shi-Hao Sun, Yi Qiang Yu, Attila Mándi, Jiaoyang Luo, Meihua Yang, Tibor Kurtán, Wen‐Hua Chen, Li Ru Shen, Jun Wu

Chemical Science

DOI

2020

Synthesis and biological effect of lysosome-targeting fluorescent anion transporters with enhanced anionophoric activity

Xiao-Qiao Hong, Xiangyu He, Kin Yip Tam, Wen‐Hua Chen

Bioorganic & Medicinal Chemistry Letters

DOI

2020

Design, synthesis and α-glucosidase inhibition study of novel embelin derivatives

Xiaole Chen, Min Gao, Rongchao Jian, Weiqian David Hong, Xiaowen Tang, Yuling Li, Deng‐Gao Zhao, Kun Zhang, Wen‐Hua Chen, Xi Zheng, Zhaojun Sheng, Panpan Wu

Journal of Enzyme Inhibition and Medicinal Chemistry

DOI

2020

Facile and recyclable dopamine sensing by a label-free terbium(III) metal−organic framework

Ke-Yang Wu, Ming Chen, Nai-Hai Huang, Rong-Tian Li, Weilun Pan, Wen‐Hua Zhang, Wen‐Hua Chen, Jin-Xiang Chen

Talanta

DOI

2020

NIRF Nanoprobes for Cancer Molecular Imaging: Approaching Clinic

Zhenhua Hu, Wen‐Hua Chen, Jie Tian, Zhen Cheng

Trends in Molecular Medicine

DOI

2020

Screening of larvicidal activity of 53 essential oils and their synergistic effect for the improvement of deltamethrin efficacy against Aedes albopictus

Zhaojun Sheng, Rongchao Jian, Fangying Xie, Bin Chen, Kun Zhang, Dongli Li, Wen‐Hua Chen, Chiguang Huang, Yan Zhang, Litao Hu, Deng‐Gao Zhao, Xi Zheng, Panpan Wu, Weiqian David Hong

Industrial Crops and Products

DOI

2019

Synthesis and biological evaluation of coumarin derivatives as α-glucosidase inhibitors

Xuetao Xu, Xu-Yang Deng, Jie Chen, Qi-Ming Liang, Kun Zhang, Dongli Li, Panpan Wu, Xi Zheng, Renping Zhou, Zhengyun Jiang, Ai‐Jun Ma, Wen‐Hua Chen, Shao‐Hua Wang

European Journal of Medicinal Chemistry

DOI

2019

Biological effects and activity optimization of small-molecule, drug-like synthetic anion transporters

Xi-Hui Yu, Xiao-Qiao Hong, Qin-Chao Mao, Wen‐Hua Chen

European Journal of Medicinal Chemistry

DOI

2019

New Applications of Oleanolic Acid and its Derivatives as Cardioprotective Agents: A Review of their Therapeutic Perspectives

Ning Sun, Dongli Li, Xiaoqing Chen, Panpan Wu, Yu‐Jing Lu, Ning Hou, Wen‐Hua Chen, Wing‐Leung Wong

Current Pharmaceutical Design

DOI

2019

Synthesis and Biological Activity of Embelin and its Derivatives: An Overview

Zhaojun Sheng, Si-Yuan Ge, Min Gao, Rongchao Jian, Xiaole Chen, Xuetao Xu, Dongli Li, Kun Zhang, Wen‐Hua Chen

Mini-Reviews in Medicinal Chemistry

DOI

2019

Sequential and recyclable sensing of Fe 3+ and ascorbic acid in water with a terbium( iii )-based metal–organic framework

Ke-Yang Wu, Liang Qin, Cheng Fan, Shao-Lan Cai, Tingting Zhang, Wen‐Hua Chen, Xiao‐Yan Tang, Jin-Xiang Chen

Dalton Transactions

DOI

精选作品

期刊论文

Structure-Based Discovery of JN210 as a Potent Dual DCN1/HDAC Inhibitor for the Treatment of Nonsmall Cell Lung Cancer

Development of Glycosylated and Dimeric FAP-Targeted Radiotracers for Preclinical Evaluation in FAP-Positive Glioblastoma Models

A bis(benzimidazolyl)-based anion transporter triggers chloride-initiated pyroptosis of MDA-MB-468 and 4T1 triple-negative breast cancer cells in vitro and in vivo

Molecularly engineered solvatochromic fluorescent probes for the recognition of nonalcoholic steatohepatitis and inflammation by the detection of lipid droplet polarity

Dual Induction of Ferroptosis and Apoptosis by Triazolopyrimidinyl Derivatives: Design, Synthesis, and Biological Evaluation for Their Anticancer Efficacy via Calcium/Calmodulin Signaling and Mitochondrial Impairment

Environmentally sensitive fluorescent probes for the visualization of selective proteins: Recent progress and biomedical applications

Ferroptosis of Cancer Cells via Tubulin Degradation and Mitochondrial Dysfunction: A Novel Mechanism of Anticancer Effect for Small-Molecule Anion Transporters

Design, synthesis and biological evaluation of Golgi-targeting anion transporters as inducers of Golgiphagy and apoptosis in cancer cells

A novel multi-site and mitochondrial-targeting fluorescent probe for selective recognition of cancer cells and sensing of hypochlorous acid in vivo

Radiosynthesis and Biological Evaluation of a Small-Molecule Probe for Thyroid-Stimulating Hormone Receptor

A lipid droplets-targeting near-infrared fluorescent probe for the specific imaging of hepatoma cells and the detection of H2S in biological systems

A reversible smartphone-based fluorescent probe for the rapid detection of ammonia in biofluids

Extraction Optimization and Bioactivity of Polysaccharides from Ganoderma leucocontextum Spores

Design, synthesis and biological evaluation of a 1,2,3-triazolyl-bearing betulinic acid derivatives as α-glucosidase inhibitors

An activatable “AIE + ESIPT” fluorescent probe for dual-imaging of lipid droplets and hydrogen peroxide in drug-induced liver injury model

Rh(III)-Catalyzed, Redox-Neutral, C–H Multifluoroalkenylation of Benzamides

Design, synthesis and biological evaluation of novel betulinic acid derivatives containing 1,2,4-triazole-derived schiff bases as α-glucosidase inhibitors

Chemical Composition of Essential Oil from Citrus reticulata Blanco cv. Chachiensis (Chachi) and Its Anti-Mosquito Activity against Pyrethroid-Resistant Aedes albopictus

Anticancer efficacy triggered by synergistically modulating the homeostasis of anions and iron: Design, synthesis and biological evaluation of dual-functional squaramide-hydroxamic acid conjugates

1,2,3-Triazole-based betulinic acid derivatives as α-glucosidase inhibitors: Synthesis and in vitro and in vivo biological evaluation

Study of the Structure and Bioactivity of Polysaccharides from Different Parts of Stemona tuberosa Lour

A novel donor-acceptor fluorescent probe for the fluorogenic/ chromogenic detection and bioimaging of nitric oxide

Identification of sedative-hypnotic compounds shared by five medicinal Polyporales mushrooms using UPLC-Q-TOF-MS/MS-based untargeted metabolomics

Recent progress in organelle-targeting fluorescent probes for the detection of peroxynitrite

Design, Synthesis, and Antitumor Efficacy of Substituted 2-Amino[1,2,4]triazolopyrimidines and Related Heterocycles as Dual Inhibitors for Microtubule Polymerization and Janus Kinase 2

Identification of 1,3,4-oxadiazolyl-containing β-carboline derivatives as novel α-glucosidase inhibitors with antidiabetic activity

Divergent synthesis of difluoromethylated indole-3-carbinols, bisindolylmethanes and indole-3-methanamines

Combined inhibition of pyruvate dehydrogenase kinase 1 and hexokinase 2 induces apoptsis in non-small cell lung cancer cell models

Epigallocatechin gallate circumvents drug‐induced resistance in non‐small‐cell lung cancer by modulating glucose metabolism and AMPK/AKT/MAPK axis

Carboxymethyl Chitosan/Sodium Alginate/Chitosan Quaternary Ammonium Salt Composite Hydrogel Supported 3J for the Treatment of Oral Ulcer

Fibroblast Activation Protein Targeting Probe with Gly–Pro Sequence for PET of Glioblastoma

Selenadiazolesbenzothiadiazole‐Based Small Donor–Acceptor–Donor Dye for Photothermal Therapy in NIR‐II Window

A tri-herb formulation protects against ethanol-induced mouse liver injury and downregulates mitogen-activated protein kinase phosphatase 1

Ultrasonic assisted extraction, characterization and gut microbiota-dependent anti-obesity effect of polysaccharide from Pericarpium Citri Reticulatae 'Chachiensis'

Evaluations of the neuroprotective effects of a dual-target isoquinoline inhibitor in the triple transgenic mouse model of Alzheimer's disease

Design, Synthesis and Antitumor Activity of Novel Selenium-Containing Tepotinib Derivatives as Dual Inhibitors of c-Met and TrxR

Synthesis of a Golgi-targeting fluorescent probe for the selective detection of chloride anions

Rh( iii )-catalyzed redox-neutral C–H alkenylation of benzamides with gem -difluorohomoallylic silyl ethers via β-H elimination

Facile access to 2-hydroxy-2-substituted indole-3-ones via a copper-catalyzed oxidative cyclization of 2-arylethynylanilines

Recent Advance in the biological activity of synephrine in Citri Reticulatae Pericarpium

Synthesis and mechanism of biological action of morpholinyl-bearing arylsquaramides as small-molecule lysosomal pH modulators

Chemical compositions and anti-mosquito activity of essential oils from Pericarpium Citri Reticulataes of different aging years

Access to 3-Amino-[1,2,4]-triazolo Pyridines and Related Heterocycles via Electrochemically Induced Desulfurative Cyclization

Larvicidal Activity of Two Rutaceae Plant Essential Oils and Their Constituents Against Aedes albopictus (Diptera: Culicidae) in Multiple Formulations

AIE-based gold nanostar-berberine dimer nanocomposites for PDT and PTT combination therapy toward breast cancer

Synthesis of difluoromethyl carbinols from the Friedel–Crafts reaction of electron-rich arenes with difluorovinyl arylsulfonates

Design, synthesis and biological evaluation of indole-based [1,2,4]triazolo[4,3-a] pyridine derivatives as novel microtubule polymerization inhibitors

Synthesis and biological activity of squaramido-tethered bisbenzimidazoles as synthetic anion transporters

Anion-Responsive Manganese Porphyrin Facilitates Chloride Transport and Induces Immunogenic Cell Death

Curvature-regulated transmembrane anion transport by a trifluoromethylated bisbenzimidazole

Discovery of benthol A and its challenging stereochemical assignment: opening up a new window for skeletal diversity of super-carbon-chain compounds

Synthesis and biological effect of lysosome-targeting fluorescent anion transporters with enhanced anionophoric activity

Design, synthesis and α-glucosidase inhibition study of novel embelin derivatives

Facile and recyclable dopamine sensing by a label-free terbium(III) metal−organic framework

NIRF Nanoprobes for Cancer Molecular Imaging: Approaching Clinic

Screening of larvicidal activity of 53 essential oils and their synergistic effect for the improvement of deltamethrin efficacy against Aedes albopictus

Synthesis and biological evaluation of coumarin derivatives as α-glucosidase inhibitors

Biological effects and activity optimization of small-molecule, drug-like synthetic anion transporters

New Applications of Oleanolic Acid and its Derivatives as Cardioprotective Agents: A Review of their Therapeutic Perspectives

Synthesis and Biological Activity of Embelin and its Derivatives: An Overview

Sequential and recyclable sensing of Fe 3+ and ascorbic acid in water with a terbium( iii )-based metal–organic framework

会议论文

Synthesis,cytotoxicity and mechanism of biological action of aza-crown ether-squaramide conjugates as anion/cation symporters

新型3-芳基黄酮乙酸类衍生物的合成及抗肿瘤活性研究

聚醚连接的吡咯-聚酰胺二聚物的合成及其金属配合物的DNA切割活性研究

研究方向