百晓学者学者目录

董波

副教授、教授、研究员、讲师,中国海洋大学

精选作品

期刊论文

2026

“组织者”百年研究:分子机制、起源演化与未来展望

杨雪灵,隗健凯,董波

《遗传》

2026

Neuron-originated Dachshund regulates tracheal tubulogenesis via Lola-Slit axis in Drosophila.

Jun-Zhi Zhu, Wenshuo Zhang, Bo Dong

Developmental Biology

2026

Identification of protein precursor for thyroid hormone synthesis in basal chordate ascidian Styela clava

Jin Zhang, Likun Yang, Brice Beinsteiner, Yun Ma, Jian-Kai Wei, Haiyan Yu, Vincent Laudet, Bo Dong

Nature Communications

2026

Mts/PP2AC Induces Cell Migration via Rho1‐Slpr‐Mediated JNK Pathway

Wenshuo Zhang, Jun-Zhi Zhu, Xiuke Ouyang, Bo Dong

The FASEB Journal

2026

A combined approach of multi-factor assessment for three ascidians invasion

Hailiang Qi, Di Liu, Bo Dong, Haiyan Yu

Biological Invasions

2026

The endoderm cell trajectory of urochordate Styela clava reveals the dual developmental origin and evolution of digestive tract

Yonghang Ge, Wei Zhang, Penghui Liu, Jianqing Bi, Haiyan Yu, Bo Dong, Jian-Kai Wei

bioRxiv

2026

Author response: Bidirectional redistribution of actomyosin drives epithelial invagination in ascidian siphon tube morphogenesis

Jinghan Qiao, Pengyu Yu, Hongzhe Peng, Wenjie Shi, Bo Li, Bo Dong

2026

Taurine-driven chemotaxis and metamorphosis in ascidian tadpole larvae

Li-Kun Yang, Qishu Qin, Jin Zhang, Ziyu Zhang, Haiyan Yu, Chengtian Zhao, Bo Dong

Science Advances

2026

Asymmetrical microtubule-organizing centers drive posterior positioning of nuclei in Ciona notochord development

Hongzhe Peng, Runyu Qiao, Jinghan Qiao, Yujie Gao, Bo Dong

Journal of Cell Science

2025

海洋无脊椎动物幼虫附着变态的化学感知研究进展

秦琪姝,董波,杨立昆

《海洋科学》

2025

萨氏海鞘早期胚胎发育的DNA 5mC甲基化特征及功能分析

孙琦,李英瑞,隗健凯,董波

《中国海洋大学学报(自然科学版)》

2025

Widespread presence of bone marrow–like hematopoietic stem cell niche in invertebrate skeletons

Shan-Shan Lian, Nai-Na Hu, Xiao-Mei Chen, Xiaoting Dai, Xuan Zhu, Runyu Qiao, Sinuo Liu, Yuan Lu, Fengmei Zhang, Feng-Zhi Sun, Zhongqi Pu, Zu-Jing Yang, Runjia Xu, Hao Wang, Liang Zhao, Qiang Xing, Shou-Jie Li, Wei Wang, Bo Dong, Ling-Ling Zhang, Jing-Jie Hu, Jing Wang, Zhen-Min Bao, Shi Wang

Science Advances

2025

Physics of notochord tube expansion in ascidians

Wen-Jie Shi, C. Duclut, Yan Xu, Yuanting Ma, Jing-Han Qiao, Boyan Lin, Dongyu Yang, Jacques Prost, Bo Dong

Proceedings of the National Academy of Sciences of the United States of America

2025

Transcriptome Analysis Reveals the Requirement of the TGFβ Pathway in Ascidian Tail Regression

Wen-Jie Shi, Penghui Liu, Dongyu Yang, Yuan Zhuang, Boyan Lin, Bo Dong

Cells

2025

Integrin‐Alpha‐6+ Cells Are Responsible for Blastema Formation During Oral Siphon Regeneration in Ciona robusta

Shuo Yan, Wenjing Xu, Yuping Fan, Penghui Liu, Wei Wang, Bo Dong, Xiuxia Yang

The FASEB Journal

2025

Halorotetin B, A Novel Terpenoid Compound Derived from Marine Ascidian, Suppresses Tumor Growth by Targeting the Cell Cycle Regulator UBE2C

Shanhao Han, Jianhui Li, Yuting Zhu, Penghui Liu, Yao-Yao Zheng, Mu-Chun He, Bo Dong

Advancement of science

2025

Development of cell labeling and gene editing tools in urochordate Ciona

Xiang Li, Lu Mu, Hongzhe Peng, Sun Nyunt Wai, Longjun Pu, Bo Dong

Marine Life Science & Technology

2025

Integrated multi-omics identify key signalling pathways for notochord lumenogenesis in ascidian Ciona savignyi

Jin Zhang, Zicheng Tan, Qishu Qin, Hongzhe Peng, Wenjie Shi, Haiyan Yu, Bo Dong

Open Biology

2024

Spatially resolved single-cell atlas of ascidian endostyle provides insight into the origin of vertebrate pharyngeal organs

An Jiang, Kai Han, Jian-Kai Wei, Xiao-Shan Su, Rui Wang, Wei Zhang, Xia-Wei Liu, Jing-Han Qiao, Penghui Liu, Qun Liu, Jin Zhang, Nannan Zhang, Yonghang Ge, Yuan Zhuang, Haiyan Yu, Shi Wang, Kai Chen, Wan-Ge Lu, Xun Xu, Huan-Ming Yang, Guang-Yi Fan, Bo Dong

Science Advances

2024

Snail Transcriptionally Represses Brachyury to Promote the Mesenchymal-Epithelial Transition in Ascidian Notochord Cells

Bingtong Wu, Xiuke Ouyang, Xiuxia Yang, Bo Dong

International Journal of Molecular Sciences

2024

Dynamics of Chromatin Opening across Larval Development in the Urochordate Ascidian Ciona savignyi

Mu-Chun He, Yu-Ting Li, Ya-Juan Li, Bo Dong, Haiyan Yu

International Journal of Molecular Sciences

2024

Temporospatial hierarchy and allele-specific expression of zygotic genome activation revealed by distant interspecific urochordate hybrids

Jian-Kai Wei, Wei Zhang, An Jiang, Hong-Zhe Peng, Quanyong Zhang, Yu-Ting Li, Jianqing Bi, Linting Wang, Penghui Liu, Jing Wang, Yonghang Ge, Liya Zhang, Haiyan Yu, Lei M. Li, Shi Wang, L. Leng, Kai Chen, Bo Dong

Nature Communications

2024

Matrix metalloproteinase Nas15 regulates the lumen formation and expansion in Ciona notochord

Jianqing Bi, Yonghang Ge, Zhuqing Wang, Hongzhe Peng, Bo Dong

Frontiers in Ecology and Evolution

2024

Non-canonical signaling initiated by hormone-responsive G protein-coupled receptors from subcellular compartments

Li-Kun Yang, Wei Wang, Dong-Yu Guo, Bo Dong

Pharmacology & Therapeutics

2023

海鞘细胞核骨架与细胞质骨架连接复合体相关基因的克隆及表达分析

乔润雨,彭鸿哲,董波

《中国海洋大学学报(自然科学版)》

2023

真海鞘根索和被囊乙醇提取物抑癌活性成分的分离及其作用机制研究

韩善浩,李建辉,祝玉婷,高宏伟,董波

《中国海洋大学学报(自然科学版)》

2023

Transcriptional Analysis of the Endostyle Reveals Pharyngeal Organ Functions in Ascidian

An Jiang, Wei Zhang, Jian-Kai Wei, Penghui Liu, Bo Dong

Biology

2023

The Conserved Transcriptional Activation Activity Identified in Dual-Specificity Tyrosine-(Y)-Phosphorylation-Regulated Kinase 1

Xiuke Ouyang, Zhuqing Wang, Bingtong Wu, Xiuxia Yang, Bo Dong

Biomolecules

2023

A collagen-rich arch in the urochordate notochord coordinates cell shaping and multi-tissue elongation.

Hong-Zhe Peng, Jing-Han Qiao, Gui-Lin Wang, Wen-Jie Shi, Fan Xia, Runyu Qiao, Bo Dong

Current Biology

2023

Proteomic identification of intracellular vesicle trafficking and protein glycosylation requirements for lumen inflation in Ciona notochord

Zhuqing Wang, Zicheng Tan, Jianqing Bi, Amei Liu, An Jiang, Bo Dong

Proteomics

2023

Editorial: Cell polarity in a complex environment

Yi Wu, Bo Dong, Benjamin C. Lin

Frontiers in Cell and Developmental Biology

2023

Halorotetin A: A Novel Terpenoid Compound Isolated from Ascidian Halocynthia rotetzi Exhibits the Inhibition Activity on Tumor Cell Proliferation

Jianhui Li, Shanhao Han, Yuting Zhu, Bo Dong

Marine Drugs

2023

Establishment of a developmental atlas and transgenetic tools in the ascidian Styela clava

Boyan Lin, Wenjie Shi, Qiongxuan Lu, Takumi T. Shito, Haiyan Yu, Bo Dong

Marine Life Science & Technology

2023

Special topic on EvoDevo: emerging models and perspectives

Hongan Long, Bo Dong

Marine Life Science & Technology

2023

Comparative Transcriptomic Analysis Reveals the Functionally Segmented Intestine in Tunicate Ascidian

Wei Zhang, An Jiang, Haiyan Yu, Bo Dong

International Journal of Molecular Sciences

2023

Development and Application of an Optogenetic Manipulation System to Suppress Actomyosin Activity in Ciona Epidermis

Jinghan Qiao, Hongzhe Peng, Bo Dong

International Journal of Molecular Sciences

2023

Quantitative Phosphoproteomics Reveals the Requirement of DYRK1-Mediated Phosphorylation of Ion Transport- and Cell Junction-Related Proteins for Notochord Lumenogenesis in Ascidian

Zhuqing Wang, Xiuke Ouyang, Zicheng Tan, Likun Yang, Bo Dong

Cells

2023

DYRK1-mediated phosphorylation of endocytic components is required for extracellular lumen expansion in ascidian notochord

Xiuke Ouyang, Bingtong Wu, Haiyan Yu, Bo Dong

Biological Research

2023

ELMOD3-Rab1A-Flotillin2 cascade regulates lumen formation via vesicle trafficking in Ciona notochord

Amei Liu, Xiuke Ouyang, Zhuqing Wang, Bo Dong

Open Biology

2022

A microRNA Cluster-Lefty Pathway is Required for Cellulose Synthesis During Ascidian Larval Metamorphosis

Xue-Ping Sun, Xiaoming Zhang, Likun Yang, Bo Dong

Frontiers in Cell and Developmental Biology

2022

EDomics: a comprehensive and comparative multi-omics database for animal evo-devo

Jian-Kai Wei, Penghui Liu, Fu-Yun Liu, An Jiang, Jing-Han Qiao, Zhongqi Pu, Bing-Rou Wang, Jin Zhang, Dongning Jia, Yu-Li Li, Shi Wang, Bo Dong

Nucleic Acids Res.

2022

High abundance of CDC45 inhibits cell proliferation through elevation of HSPA6

Yuanyuan Fu, Zhi-Yi Lv, D. Kong, Yuping Fan, Bo Dong

Cell Proliferation

2022

Nuclear Factor of Activated T Cells-5 Regulates Notochord Lumenogenesis in Chordate Larval Development

Mu-Chun He, Jian-Kai Wei, Yu-Ting Li, Bo Dong

International Journal of Molecular Sciences

2022

Molecular Characterization and Expression Analysis of Putative Class C (Glutamate Family) G Protein-Coupled Receptors in Ascidian Styela clava

Jin Zhang, Bo Dong, Likun Yang

Biology

2022

Aqueous Extract of Sea Squirt (Halocynthia roretzi) with Potent Activity against Human Cancer Cells Acts Synergistically with Doxorubicin

Yuting Zhu, Shanhao Han, Jianhui Li, Hongwei Gao, Bo Dong

Marine Drugs

2022

Ancestral glycoprotein hormone and its cognate receptor present in primitive chordate ascidian: Molecular identification and functional characterization

Li-Kun Yang, Jin Zhang, Di Liu, Tong-Ye Han, Qishu Qin, Anqi Wang, Bo Dong

International Journal of Biological Macromolecules

2022

Antidiabetic activity and metabolite profiles of ascidian Halocynthia roretzi

Yuting Zhu, Hongwei Gao, Shanhao Han, Jianhui Li, Qiqin Wen, Bo Dong

Journal of Functional Foods

2022

Cultivation of gut microorganisms of the marine ascidian Halocynthia roretzi reveals their potential roles in the environmental adaptation of their host

Yang Yang, Yuting Zhu, Haiming Liu, Jiankai Wei, Haiyan Yu, Bo Dong

Marine Life Science & Technology

2021

MiR-92 Family Members Form a Cluster Required for Notochord Tubulogenesis in Urochordate Ciona savignyi

Li-Bo Yang, Xiaoming Zhang, Cheng-Zhang Liu, Jin Zhang, Bo Dong

Genes

2021

Development of a miRNA Sensor by an Inducible CRISPR-Cas9 Construct in Ciona Embryogenesis

Zhuqing Wang, Xue-Ping Sun, Xiaoming Zhang, Bo Dong, Hai-Yang Yu

Molecular Biotechnology

2021

Genome-Wide Identification, Comparison, and Expression Analysis of Transcription Factors in Ascidian Styela clava

Jin Zhang, Jian-Kai Wei, Hai-Yang Yu, Bo Dong

International Journal of Molecular Sciences

2021

Biodiversity-based development and evolution: the emerging research systems in model and non-model organisms

Long Zhao, Feng Gao, Shan Gao, Yujun Liang, Hongan Long, Zhi-Yi Lv, Ying Su, Nai-Hao Ye, Liusuo Zhang, Chengtian Zhao, Xiaoyu Wang, Wei-Bo Song, Shi-Cui Zhang, Bo Dong

Science China Life Sciences

2021

Origin of the Chordate Notochord

Zihao Sui, Zhihan Zhao, Bo Dong

Diversity

2020

Evolutionary transcriptomics of metazoan biphasic life cycle supports a single intercalation origin of metazoan larvae (vol 17, pg 351, 2020)

Jing Wang, Lingling Zhang, Shanshan Lian, Zhenkui Qin, Xuan Zhu, Xiaoting Dai, Zekun Huang, Caihuan Ke, Zunchun Zhou, Jiankai Wei, Pingping Liu, Naina Hu, Qifan Zeng, Bo Dong, Ying Dong, Dexu Kong, Zhifeng Zhang, Sinuo Liu, Yu Xia, Yangping Li, Liang Zhao, Qiang Xing, Xiaoting Huang, Xiaoli Hu, Zhenmin Bao, Shi Wang

Nature Ecology & Evolution,Vol. 40, No. 50

2020

Evolutionary transcriptomics of metazoan biphasic life cycle supports a single intercalation origin of metazoan larvae

Jing Wang, Lingling Zhang, Shanshan Lian, Zhenkui Qin, Xuan Zhu, Xiaoting Dai, Zekun Huang, Caihuan Ke, Zunchun Zhou, Jiankai Wei, Pingping Liu, Naina Hu, Qifan Zeng, Bo Dong, Ying Dong, Dexu Kong, Zhifeng Zhang, Sinuo Liu, Yu Xia, Yangping Li, Liang Zhao, Qiang Xing, Xiaoting Huang, Xiaoli Hu, Zhenmin Bao, Shi Wang

Nature Ecology & Evolution,Vol. 40, No. 50

2020

Identification and population genetic comparison of three ascidian species based on mtDNA sequences

Punit Bhattachan, Runyu Qiao, Bo Dong

Ecology And Evolution,Vol. 10, No. 8

2020

Polarity Establishment and Maintenance in Ascidian Notochord

Hong-Zhe Peng, Runyu Qiao, Bo Dong

Frontiers in Cell and Developmental Biology

2020

Ciona embryonic tail bending is driven by asymmetrical notochord contractility and coordinated by epithelial proliferation

Qiong-Xuan Lu, Yuan Gao, Yuanyuan Fu, Hong-Zhe Peng, Wenjie Shi, Bo Li, Zhi-Yi Lv, Xi-Qiao Feng, Bo Dong

Development

2020

A single-cell analysis of the molecular lineage of chordate embryogenesis

Teng-Jiao Zhang, Yi-Chi Xu, K. Imai, T. Fei, Gui-Lin Wang, Bo Dong, Tian-Wei Yu, Y. Satou, Wei-Yang Shi, Zhi-Rong Bao

Science Advances

2020

Seasonal dynamics and starvation impact on the gut microbiome of urochordate ascidian Halocynthia roretzi

Jian-Kai Wei, Hong-Wei Gao, Yang Yang, Haiming Liu, Hai-Yang Yu, Zigui Chen, Bo Dong

Animal Microbiome

2019

Identification and functional characterization of solute carrier family 6 genes in Ciona savignyi.

Ping Ren, Jian-Kai Wei, Hai-Yang Yu, Bo Dong

Gene

2019

Origins and Bioactivities of Natural Compounds Derived from Marine Ascidians and Their Symbionts

Xiao-Ju Dou, Bo Dong

Marine Drugs

2019

Ascidian notochord elongation.

Qiong-Xuan Lu, Punit Bhattachan, Bo Dong

Developmental Biology

2019

Multivariate analysis of genomic variables, effective population size, and mutation rate

Punit Bhattachan, Bo Dong

BMC Research Notes

2019

Ascidian caveolin induces membrane curvature and protects tissue integrity and morphology during embryogenesis

Punit Bhattachan, James Rae, Hai-Yang Yu, WooRam Jung, Jian-Kai Wei, R. Parton, Bo Dong

The FASEB Journal

2019

Identification and functional characterization of lactadherin, an agglutinating glycoprotein from the chordate Styela clava

Xin Hua Guo, Xiaoju Dou, Bo Dong

In Vitro Cellular & Developmental Biology - Animal

2019

Morphogenesis: a focus on marine invertebrates

Zhiyi Lv, Qiongxuan Lu, Bo Dong

Marine Life Science & Technology

2018

海洋动物microRNAs研究进展与展望

刘小卓,张晓明,董波

《海洋科学》

2018

Identification and characterization of microRNAs involved in ascidian larval metamorphosis

Xiaoming Zhang, Xiao-Zhuo Liu, Cheng-Zhang Liu, Jian-Kai Wei, Hai-Yang Yu, Bo Dong

BMC Genomics

2018

Dual Roles of Ascidian Chondromodulin-1: Promoting Cell Proliferation Whilst Suppressing the Growth of Tumor Cells

Xiao-Ju Dou, Xiang Li, Hai-Yang Yu, Bo Dong

Marine Drugs

2018

The discovered chimeric protein plays the cohesive role to maintain scallop byssal root structural integrity

Pingping Xu, Xiaoting Dai, Dandan Wang, Y. Miao, Xiaokang Zhang, Shuo-Shuo Wang, Luyao Teng, Bo Dong, Z. Bao, Shi Wang, Qianqian Lyu, Wei-Zhi Liu

Scientific Reports

2018

The impact of acute thermal stress on green mussel Perna viridis: Oxidative damage and responses.

Jing Wang, Bo Dong, Zhen-Xing Yu, Cui-Luan Yao

Comparative biochemistry and physiology. Part A, Molecular & integrative physiology

2018

Characterization of an Atypical Metalloproteinase Inhibitors Like Protein (Sbp8-1) From Scallop Byssus

Xiaokang Zhang, Xiaoting Dai, Lu-Lu Wang, Y. Miao, Pingping Xu, Pengyu Liang, Bo Dong, Z. Bao, Shi Wang, Qianqian Lyu, Wei-Zhi Liu

Frontiers in Physiology

2018

Identification and expression analysis of long noncoding RNAs in embryogenesis and larval metamorphosis of Ciona savignyi.

Jian-Kai Wei, Bo Dong

Marine Genomics

2017

Scallop genome provides insights into evolution of bilaterian karyotype and development

Shi Wang, Jinbo Zhang, Wenqian Jiao, Ji Li, Xiaogang Xun, Yan Sun, Ximing Guo, Pin Huan, Bo Dong, Lingling Zhang, Xiaoli Hu, Xiaoqing Sun, Jing Wang, Chengtian Zhao, Yangfan Wang, Dawei Wang, Xiaoting Huang, Ruijia Wang, Jia Lv, Yuli Li, Zhifeng Zhang, Baozhong Liu, Wei Lu, Yuanyuan Hui, Jun Liang, Zunchun Zhou, Rui Hou, Xue Li, Yunchao Liu, Hengde Li, Xianhui Ning, Yu Lin, Liang Zhao, Qiang Xing, Jinzhuang Dou, Yangping Li, Junxia Mao, Haobing Guo, Huaiqian Dou, Tianqi Li, Chuang Mu, Wenkai Jiang, Qiang Fu, Xiaoteng Fu, Yan Miao, Jian Liu, Qian Yu, Ruojiao Li, Huan Liao, Xuan Li, Yifan Kong, Zhi Jiang, Daniel Chourrout, Ruiqiang Li, Zhenmin Bao

Nature Ecology & Evolution,Vol. 10, No. 50

2017

Architectural delineation and molecular identification of extracellular matrix in ascidian embryos and larvae

Jian-Kai Wei, Gui-Lin Wang, Xiang Li, Ping Ren, Hai-Yang Yu, Bo Dong

Biology Open

2017

Origin and evolutionary implications of introns from analysis of cellulose synthase gene

Punit Bhattachan, Bo Dong

2017

Shape and geometry control of the Drosophila tracheal tubule

Shigeo Hayashi, Bo Dong

Development Growth & Differentiation

2015

Cortical instability drives periodic supracellular actin pattern formation in epithelial tubes

É. Hannezo, Bo Dong, P. Recho, J. Joanny, S. Hayashi

Proceedings of the National Academy of Sciences of the United States of America

2015

Regulation by a TGFβ-ROCK-actomyosin axis secures a non-linear lumen expansion that is essential for tubulogenesis

Elsa Denker, Ivonne M. Sehring, Bo Dong, Julien Audisso, Birthe Mathiesen, Di Jiang

Development

2015

Assembly and positioning of actomyosin rings by contractility and planar cell polarity

Ivonne M. Sehring, Pierre Recho, Elsa Denker, Matthew J. Kourakis, Birthe Mathiesen, Édouard Hannezo, Bo Dong, Di Jiang

eLife

2015

Author response: Assembly and positioning of actomyosin rings by contractility and planar cell polarity

Ivonne M. Sehring, Pierre Recho, Elsa Denker, Matthew J. Kourakis, Birthe Mathiesen, Édouard Hannezo, Bo Dong, Di Jiang

2015

Shaping of biological tubes by mechanical interaction of cell and extracellular matrix

Bo Dong, Shigeo Hayashi

Current Opinion in Genetics & Development

2013

基于中国明对虾不同组织EST数据的基因表达差异分析

隗健凯,柳承璋,张晓军,王兵,董波,李富花,相建海

《水产学报》

2013

Differential gene expression analysis based on expressed sequence tags(EST) from different tissues of Fenneropenaeus chinensis

Jian-Kai Wei, Cheng-Zhang Liu, Xiaojun Zhang, Bing Wang, Bo Dong, Fuhua Li, J. Xiang

2004

养殖期中国对虾抗菌肽的表达

郭振宇,董波,焦传珍,相建海

《海洋科学》

2004

生物信息学现状及我国海洋生物信息学应用展望

董波,相建海

《海洋科学》

2000

滤食性贝类摄食生理的研究进展

董波,薛钦昭,李军

《海洋科学》

1999

海洋滤食性贝类摄食率的研究现状

董波,薛钦昭,李军

《海洋科学》

会议论文

2017

miR-4055通过AKT-MAPK信号通路调控海鞘幼虫感觉器官的形态发生和功能

刘小卓,张晓明,董波

《2017年中国水产学会学术年会》

2001

贝类生物能量学的研究

董波

《中国科学院海洋科学青年学术研讨会暨2001年海洋湖沼科学青年学者论坛论文摘要集》

预印本

2022

Spatiotemporal dynamics of zygotic genome activation in basal chordates revealed by interspecific hybrids

Jiankai Wei, Wei Zhang, Liang Leng, An Jiang, Yuting Li, Yonghang Ge, Quanyong Zhang, Liya Zhang, Haiyan Yu, Kai Chen, Bo Dong

bioRxiv (Cold Spring Harbor Laboratory)

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