百晓学者学者目录

邹志鹏

副教授、博士生导师、教授、讲师，南方医科大学

精选作品

期刊论文

2026

Acetyl-CoA synthase 1 mediates metabolic reprogramming to promote proliferation and metastasis of osteosarcoma

Xiuming He, Mengliang Luo, Chenyang Wang, Lingkai Kong, Jianglong Li, Jianye Tan, Junhao Chen, Yi Nie, Hantao Chen, Zhipeng Zou, Zexin Su, Lin Li

Journal of Orthopaedic Translation

DOI

2025

Gut symbiont-derived ursodeoxycholic acid promotes fatty acid oxidation to protect against renal ischemia-reperfusion injury

Ming Xie, Jun Zheng, Yu Yao, Qishen Yang, Zhipeng Zhou, Jingwen Xue, Benlin Wang, Yifeng Qiu, Zhangrui Zhu, Qi Sun, Xinhang Shi, Wentai Shangguan, Leqian Li, Zhipeng Zou, Jie Zhao, Peng Wu

Cell Reports Medicine

DOI

2025

Author Correction: Damaged brain accelerates bone healing by releasing small extracellular vesicles that target osteoprogenitors

Wei Xia, Jing Xie, Zhiqing Cai, Xuhua Liu, Jing Wen, Zhong‐Kai Cui, Run Zhao, Xiaomei Zhou, Jiahui Chen, Xinru Mao, Zhengtao Gu, Zhimin Zou, Zhipeng Zou, Yue Zhang, Ming Fei Zhao, Maegele Mac, Qiancheng Song, Xiaochun Bai

Nature Communications

DOI

2025

Brown adipose tissue secretes OLFM4 to coordinate sensory and sympathetic innervation via Schwann cells

Mingqiang Lai, Wu Zhou, Wenchong Zou, Lianlian Qiu, Zhaoyu Liang, Wanyi Chen, Yiqing Wang, Bin Guo, Chaoran Zhao, Zhisheng Zhang, Pinglin Lai, Le Hu, Xiaolin Liu, Yu Jiang, Yinghua Chen, Minjun Huang, Xiaochun Bai, Zhipeng Zou

Nature Communications

DOI

2024

A RANKL-UCHL1-sCD13 negative feedback loop limits osteoclastogenesis in subchondral bone to prevent osteoarthritis progression

Wenquan Liang, Ru Feng, Xiaojia Li, Xingwei Duan, Shourui Feng, Jun Chen, Yicheng Li, Junqi Chen, Zezheng Liu, Xiaogang Wang, Guangfeng Ruan, Su’an Tang, Changhai Ding, Bin Huang, Zhipeng Zou, Tianyu Chen

Nature Communications

DOI

2024

A human organoid drug screen identifies α2-adrenergic receptor signaling as a therapeutic target for cartilage regeneration

Xiaocui Wei, Jingyang Qiu, Ruijun Lai, Tiantian Wei, Zhijie Lin, Shijiang Huang, Yuanjun Jiang, Zhanpeng Kuang, Hao Zeng, Yan Meng Gong, Xiaoling Xie, Jun Jie Yang, Yue Zhang, Sheng Zhang, Zhipeng Zou, Xuefei Gao, Xiaochun Bai

Cell stem cell

DOI

2024

An integrated multi-omics analysis reveals osteokines involved in global regulation

Wenquan Liang, Tiantian Wei, Le Hu, Meijun Chen, Liping Tong, Zhou Wu, Xingwei Duan, Xiaoyang Zhao, Weijie Zhou, Qing Yan Jiang, Guozhi Xiao, Weiguo Zou, Di Chen, Zhipeng Zou, Xiaochun Bai

Cell Metabolism

DOI

2024

Whitening of brown adipose tissue inhibits osteogenic differentiation via secretion of S100A8/A9

Ting Wang, Chaoran Zhao, Jiahuan Zhang, Shengfa Li, Youming Zhang, Yan Gong, Yingyue Zhou, Lei Yan, Sheng Zhang, Zhongmin Zhang, Hongling Hu, Anling Liu, Xiaochun Bai, Zhipeng Zou

iScience

DOI

2023

ANGPTL4 binds to the leptin receptor to regulate ectopic bone formation

Hongling Hu, Sheng Luo, Pinglin Lai, Mingqiang Lai, Linlin Mao, Sheng Zhang, Yuanjun Jiang, Jiaxin Wen, Zhou Wu, Xiaolin Liu, Liang Wang, Minjun Huang, Yanjun Hu, Xiaoyang Zhao, Laixin Xia, Weijie Zhou, Yu Jiang, Zhipeng Zou, Anling Liu, Bin Guo, Xiaochun Bai

Proceedings of the National Academy of Sciences

DOI

2023

Loss of RanGAP1 drives chromosome instability and rapid tumorigenesis of osteosarcoma

Yan Gong, Shitian Zou, Daizhao Deng, Liang Wang, Hongling Hu, Zeyou Qiu, Tiantian Wei, Panpan Yang, Jielong Zhou, Yu Zhang, Weiliang Zhu, Xiaoling Xie, Zhengquan Liao, Jun J.J. Yang, Sheng Zhang, Anling Liu, Yu Jiang, Zhipeng Zou, Xiaochun Bai

Developmental Cell

DOI

2023

Exosome Release Delays Senescence by Disposing of Obsolete Biomolecules

Wenchong Zou, Mingqiang Lai, Yuanjun Jiang, Linlin Mao, Zhou Wu, Sheng Zhang, Pinglin Lai, Bin Guo, Tiantian Wei, Chengtao Nie, Lei Zheng, Jiahuan Zhang, Xuefei Gao, Xiaoyang Zhao, Laixin Xia, Zhipeng Zou, Anling Liu, Shiming Liu, Zhong‐Kai Cui, Xiaochun Bai

Advanced Science

DOI

2022

Deletion of Rheb1 in Osteocytes Leads to Osteopenia Characterized by Reduced Bone Formation and Enhanced Bone Resorption

Jun Yang, Wuju Zhang, Eryong Lai, Wen Liu, Pinglin Lai, Zhipeng Zou, Weidong Wang, Xiaochun Bai

DNA and Cell Biology

DOI

2022

DNMT1 is a negative regulator of osteogenesis

Tao Chen, Jia Liu, Ziqi Li, Pinglin Lai, Sheng Zhang, Jiankun Qu, Yujin Tang, Anling Liu, Zhipeng Zou, Xiaochun Bai, Jianwei Li

Biology Open

DOI

2021

Damaged brain accelerates bone healing by releasing small extracellular vesicles that target osteoprogenitors

Wei Xia, Jing Xie, Zhiqing Cai, Xuhua Liu, Jing Wen, Zhong‐Kai Cui, Run Zhao, Xiaomei Zhou, Jiahui Chen, Xinru Mao, Zhengtao Gu, Zhimin Zou, Zhipeng Zou, Yue Zhang, Ming Fei Zhao, Maegele Mac, Qiancheng Song, Xiaochun Bai

Nature Communications

DOI

2021

Tsc1 regulates tight junction independent of mTORC1

Mingqiang Lai, Wenchong Zou, Zelong Han, Ling Zhou, Zeyou Qiu, Juan Chen, Sheng Zhang, Pinglin Lai, Kai Li, Yue Zhang, Li Liang, Yu Jiang, Zhipeng Zou, Xiaochun Bai

Proceedings of the National Academy of Sciences

DOI

2021

Vangl2 limits chaperone-mediated autophagy to balance osteogenic differentiation in mesenchymal stem cells

Yan Gong, Ziqi Li, Shitian Zou, Daizhao Deng, Pinglin Lai, Hongling Hu, Yongzhou Yao, Le Hu, Sheng Zhang, Kai Li, Tiantian Wei, Xiaoyang Zhao, Guozhi Xiao, Zifeng Chen, Yu Jiang, Xiaochun Bai, Zhipeng Zou

Developmental Cell

DOI

2021

Analysis of the mTOR Interactome using SILAC technology revealed NICE-4 as a novel regulator of mTORC1 activity

Yun Wang, Zhenguo Chen, Chunhong Jia, Xiaochun Bai, Yu Jiang, Zhipeng Zou

Life Sciences

DOI

2021

Osteocytes regulate neutrophil development through IL-19: A potent cytokine for neutropenia treatment.

Min Xiao, Wu-Ju Zhang, Wen Li, Linlin Mao, Jin-Cheng Yang, Le Hu, Sheng Zhang, Ya-Ling Zheng, Anling Liu, Q. Song, Yu-Hua Li, G. Xiao, Zhipeng Zou, Xiao-Chun Bai

Blood

DOI

2020

DEPTOR Prevents Osteoarthritis Development Via Interplay With TRC8 to Reduce Endoplasmic Reticulum Stress in Chondrocytes

Kai Li, Panpan Yang, Yuwei Zhang, Yue Zhang, He Cao, Peilin Liu, Bin Huang, Song Xu, Pinglin Lai, Guanghua Lei, Jia Liu, Yujin Tang, Xiaochun Bai, Zhipeng Zou

Journal of Bone and Mineral Research

DOI

2019

Osteocyte TSC1 promotes sclerostin secretion to restrain osteogenesis in mice

Wen Liu, Zhenyu Wang, Jun Yang, Yongkui Wang, Kai Li, Bin Huang, Bo Yan, Ting Wang, Mangmang Li, Zhipeng Zou, Jian Yang, Guozhi Xiao, Zhong‐Kai Cui, Anling Liu, Xiaochun Bai

Open Biology

DOI

2019

N‐(3‐methoxybenzyl)‐(9Z,12Z,15Z)‐octadecatrienamide promotes bone formation via the canonical Wnt/β‐catenin signaling pathway

Ting Wang, Chunhan Sun, Haobo Zhong, Yan Gong, Zhong‐Kai Cui, Jing Xie, Yan‐peng Wang, Chuang Liang, He‐he Cao, Xiaorui Chen, Zhipeng Zou, Shengfa Li, Xiaochun Bai

Phytotherapy Research

DOI

2018

Exosome Release Is Regulated by mTORC1

Wenchong Zou, Mingqiang Lai, Yue Zhang, Lei Zheng, Zhe Xing, Ting Li, Zhipeng Zou, Qiancheng Song, Xiaoyang Zhao, Laixin Xia, Jian Yang, Anling Liu, Han Zhang, Zhong‐Kai Cui, Yu Jiang, Xiaochun Bai

Advanced Science

DOI

2018

Colonic epithelial mTORC1 promotes ulcerative colitis through COX-2-mediated Th17 responses

Xiaojun Lin, Qiuyi Sun, Ling Zhou, Minhong He, Xiaoying Dong, Mingqiang Lai, Miao Liu, Yongchun Su, Chunhong Jia, Zelong Han, Side Liu, Hang Zheng, Yu Jiang, Hui Yvonne Ling, Mangmang Li, Juan Chen, Zhipeng Zou, Xiaochun Bai

Mucosal Immunology

DOI

2018

Raptor directs Sertoli cell cytoskeletal organization and polarity in the mouse testis†

Zhi Qiang Xiong, Caixia Wang, Zilong Wang, Huaiqian Dai, Qiancheng Song, Zhipeng Zou, Bo Xiao, Allen Zijian Zhao, Xiaochun Bai, Zhenguo Chen

Biology of Reproduction

DOI

2018

Loss of DEPTOR in renal tubules protects against cisplatin-induced acute kidney injury

Caixia Wang, Huaiqian Dai, Zhi Qiang Xiong, Qiancheng Song, Zhipeng Zou, Mangmang Li, Jing Nie, Xiaochun Bai, Zhenguo Chen

Cell Death and Disease

DOI

2017

Inactivation of mTORC1 Signaling in Osterix-Expressing Cells Impairs B-cell Differentiation

Yongkui Wang, Min Xiao, Tao Chen, Jing Chen, Zhenyu Wang, Jun Yang, Zhenguo Chen, Zhipeng Zou, Anling Liu, Daozhang Cai, Yu Jiang, Changhai Ding, Mangmang Li, Xiaochun Bai

Journal of Bone and Mineral Research

DOI

2017

Osteoblasts support megakaryopoiesis through production of interleukin-9.

Min Xiao, Yong-Kui Wang, Chen Tao, Zhenyu Wang, Jun Yang, Zhen-Guo Chen, Zhipeng Zou, Mang-Mang Li, Anling Liu, Chunhong Jia, Bin Huang, B. Yan, Ping-Lin Lai, C. Ding, D. Cai, G. Xiao, Yu Jiang, Xiao-Chun Bai

Blood

DOI

2016

Neuronal mTORC1 Is Required for Maintaining the Nonreactive State of Astrocytes

Yue Zhang, Song Xu, Kangyan Liang, Kai Li, Zhipeng Zou, Cuilan Yang, Kang Tan, Xiong Cao, Yu Jiang, Tianming Gao, Xiaochun Bai

Journal of Biological Chemistry

DOI

2016

Elevation of n-3/n-6 PUFAs ratio suppresses mTORC1 and prevents colorectal carcinogenesis associated with APC mutation

Miao Liu, Ling Zhou, Baiyu Zhang, Minhong He, Xiaoying Dong, Xiaojun Lin, Chunhong Jia, Xiaochun Bai, Yifan Dai, Yongchun Su, Zhipeng Zou, Hang Zheng

Oncotarget

DOI

2016

mTORC1 Activation Promotes Spermatogonial Differentiation and Causes Subfertility in Mice1

Caixia Wang, Zilong Wang, Zhi Xiong, Huaiqian Dai, Zhipeng Zou, Chunhong Jia, Xiao-Chun Bai, Zhen-Guo Chen

Biology of Reproduction

DOI

2016

Pinoresinol Diglucoside Alleviates oxLDL-Induced Dysfunction in Human Umbilical Vein Endothelial Cells

Jin-Peng Yao, Zhipeng Zou, Xiangfen Wang, Xiao-Ping Ji, Jun Yang

Evidence-Based Complementary and Alternative Medicine

DOI

2016

Targeted Inhibition of Rictor/mTORC2 in Cancer Treatment: A New Era after Rapamycin.

Zhipeng Zou, Juan Chen, Jun Yang, Xiao-Chun Bai

Current Cancer Drug Targets

DOI

2015

mTORC2 promotes cell survival through c-Myc–dependent up-regulation of E2F1

Zhipeng Zou, Juan Chen, Anling Liu, Xuan Zhou, Qiancheng Song, Chunhong Jia, Zhenguo Chen, Jun Lin, Cuilan Yang, Ming Li, Yu Jiang, Xiaochun Bai

The Journal of Cell Biology

DOI

2015

A phosphoproteomic study reveals shp-1 cleavage reprograms LPS signaling via a PI-3K/NF-κB and mTORC1 related mechanism

Enwu Xu, Juan Chen, Yu Wang, Zhiyong Ke, Shen-qiu Luo, Zhipeng Zou

Journal of Proteomics

DOI

2015

Diagnostic and Prognostic Applications of MicroRNA-Abundant Circulating Exosomes

B. Arnone, Xiaoqi Zhao, Zhipeng Zou, Gangjian Qin, M. Cheng

DOI

2013

TGF-β1诱导的肿瘤细胞CSRNP1/AXUD1基因的表达及转录调节机制

邓凡，李松玉，许万福，邹志鹏，柯志勇，曾方银

《南方医科大学学报》

2013

[AXIN1-related CSRNP1 mRNA expression and its transcriptional regulation in TGF-β1-induced tumor cells].

F. Deng, Song-Yu Li, Wan-Fu Xu, Zhipeng Zou, Zhi-Yong Ke, Fangyin Zeng

Nan fang yi ke da xue xue bao = Journal of Southern Medical University

2012

PKD2 and PKD3 Promote Prostate Cancer Cell Invasion via uPA by Shifting Balance Between NF-κB and HDAC1

Zhipeng Zou, Fangyin Zeng, Wanfu Xu, Chunxia Wang, Zhiyong Ke, Qiming Jane Wang, Fan Deng

Journal of Cell Science

DOI

2011

二甲双胍对肾癌细胞凋亡的影响及机制

李明，刘俊，胡卫列，贾春宏，李海燕，温芝华，邹志鹏，白晓春，罗深秋

《南方医科大学学报》

2011

[Effect of metformin on apoptosis of renal cell carcinoma cells in vitro and its mechanisms].

Ming Li, Jun Liu, Wei-lie Hu, Chun-Hong Jia, Haiyuan Li, Zhi-Hua Wen, Zhipeng Zou, Xiao-Chun Bai, Shen-qiu Luo

Nan fang yi ke da xue xue bao = Journal of Southern Medical University

2010

蛋白激酶D3对前列腺癌细胞中基质金属蛋白酶7的负调控作用

邹志鹏，冯丽，许万福，柯志勇，Wang Q.Jane，邓凡

《南方医科大学学报》

2010

PKD3上调前列腺癌细胞中PSA表达及机制

邓凡，王春霞，许万福，冯丽，柯志勇，Wang Q.Jane，邹志鹏

《南方医科大学学报》

2010

[PKD3 contributes to up-regulation of prostate-specific antigen in prostate cancer cells].

F. Deng, Chun-Xia Wang, Wan-Fu Xu, Li Feng, Zhi-Yong Ke, Q. J. Wang, Zhipeng Zou

Nan fang yi ke da xue xue bao = Journal of Southern Medical University

2010

[Protein kinase D3 is involved in negative regulation of MMP-7 in prostate cancer cells].

Zhipeng Zou, Li Feng, Wan-Fu Xu, Zhi-Yong Ke, Q. J. Wang, F. Deng

Nan fang yi ke da xue xue bao = Journal of Southern Medical University

2008

Mechanism underlying the epidermal growth factor-mediated nuclear translocation of NF-κB in glioblastoma U-87MG cells

Ting Pan, Zhipeng Zou, Jun Lin, Shen-qiu Luo

DOI

2007

亲和磷酸蛋白组学——筛选LPS信号通路中调节蛋白的新方法

邹志鹏，李煜生，陈娟，姜勇

《南方医科大学学报》

2007

应用亲和磷酸蛋白质组学筛选氧化应激重塑型LPS通路的侯选信号分子

邹志鹏，潘婷，李煜生，刘炜，朱振宇，姜勇

《中国病理生理杂志》

2007

Antitumour effects on human colorectal carcinomas cells by stable silencing of phospholipase C-gamma 1 with lentivirus-delivered siRNA

Li TAN, Bingxiang Xiao, Weisen Zeng, Jun Lin, Zhipeng Zou, Aimin Xu, Shen-qiu Luo

Chinese Medical Journal

DOI

2007

[Phosphoprotein affinity profiling--a novel method for screening regulators of lipopolysaccharide signaling pathway].

Zhipeng Zou, Yu-sheng Li, Juan Chen, Yong Jiang

Nan fang yi ke da xue xue bao = Journal of Southern Medical University

2007

[Effects of blocking phospholipase C-gamma1 signaling pathway on proliferation and apoptosis of human colorectal cancer cell line LoVo].

Jun Liu, Ming Li, B. Cheng, Wei-Sen Zeng, Zhipeng Zou, Shen-qiu Luo

Ai zheng = Aizheng = Chinese journal of cancer

2007

慢病毒导入的PLC-γ1 siRNA对人大肠癌细胞运动的影响

谭丽，邹志鹏，林骏，罗深秋

《中华肿瘤防治杂志》

2006

苯巴比妥钠对新生大鼠离体延髓脑片节律性呼吸的影响

陈娟，邹志鹏，吴中海

《南方医科大学学报》

2006

[Effects of pentobarbital sodium on rhythmical respiration of neonatal rat medullary preparations].

Juan Chen, Zhipeng Zou, Zhong-Hai Wu

Nan fang yi ke da xue xue bao = Journal of Southern Medical University

2005

Reactive Oxygen Species Stimulates Receptor Activator of NF-κB Ligand Expression in Osteoblast*

Xiao-Chun Bai, Di Lu, An-Ling Liu, Zhong Zhang, Xiu-mei Li, Zhipeng Zou, Wei-Sen Zeng, B. Cheng, Shen-qiu Luo

Journal of Biological Chemistry

DOI

2003

EGFR反义RNA的转染对人类鼻咽癌CNE-2细胞EGFR的表达下调及恶性表型的抑制(英文)

邓凡，王瑜，曾方银，邹志鹏，白晓春，陆地，柯志勇，罗深秋

《南方医科大学学报》

2003

Antisense epidermal growth factor receptor (EGFR) transfection down-regulates EGFR expression and suppresses the malignant phenotype of human nasopharyngeal carcinoma CNE-2 cell line.

F. Deng, Yu Wang, Fangyin Zeng, Zhipeng Zou, Xiao-Chun Bai, Di Lu, Zhi-Yong Ke, Shen-qiu Luo

Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA

2002

Phospholipase C-gamma1 is required for cell survival in oxidative stress by protein kinase C.

Xiao-Chun Bai, F. Deng, An-Ling Liu, Zhipeng Zou, Yu Wang, Zhi-Yong Ke, Q. Ji, Shen-qiu Luo

Biochemical Journal

DOI

2002

Phospholipase C-γI Is Required for Survival in Heat Stress: Involvement of Protein Kinase C-Depertment Bel-2 Phosphorylation

Xiao-Chun Bai, An-Ling Liu, F. Deng, Zhipeng Zou, J. Bai, Q. Ji, Shen-qiu Luo

DOI

2002

Phospholipase C-gamma1 is required for survival in heat stress: involvement of protein kinase C-dependent Bcl-2 phosphorylation.

Xiao-Chun Bai, An-Ling Liu, F. Deng, Zhipeng Zou, J. Bai, Q. Ji, Shen-qiu Luo

Journal of Biochemistry (Tokyo)

预印本

2025

Association of Skeletal Health with Major Chronic Diseases: A Prospective Cohort Study of the UK Biobank

Meijun Chen, Xiaoqing Yan, Zhipeng Zou, Wenquan Liang, Xiaochun Bai

SSRN Electronic Journal

DOI

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