刘洋｜复旦大学｜学者主页

2026

病毒膜融合蛋白构象转变机制与稳定策略

解宸一，董翔歌，战久宇，朱洪伟，于馨，刘洋，于佳玉，张兴晓

《生物化学与生物物理进展》

2026

融合靶向递送与免疫调控的卒中仿生纳米治疗策略（英文）

刘洋

《生物化学与生物物理进展》

DOI

2026

碱基编辑技术及其在斑马鱼中的开发应用

郑少辉，刘洋，夏新欣，刘彦梅

《遗传》

DOI

2026

IL-17信号通路调控机制及其在炎症性疾病中的干预策略研究

刘洋，陈荧荧，魏子茹，张肖林，赵洪春

《细胞与分子免疫学杂志》

DOI

2025

BMP9通过Wnt/β-catenin和VEGFa信号诱导前脂肪细胞成骨分化

王景江，刘洋

《中国细胞生物学学报》

2025

实现精准癌症免疫疗法的工程化脂质体纳米平台:推进生物医学创新（英文）

刘洋，武照雅，王子熙，汗穆罕默德·卡姆兰，吴富根

Science China Materials

2024

蛋白质翻译重编程在肿瘤中的研究进展

范颖，刘洋，刘雁勇

《基础医学与临床》

2024

HAX1的生物学特性及其与临床疾病关系

刘洋，张新宇，荣琼，亓明月，郭慧

《中国细胞生物学学报》

2024

脑靶向寡核苷酸药物策略用于衰老相关脑部疾病治疗

杨灏颖，刘润涵，房梦珂，刘洋，郑蒙

《生物化学与生物物理进展》

2022

碱基编辑器在基因治疗中的潜在安全性风险及解决方案研究进展

刘洋，吴运琴，彭晓华，邹庆剑，赖良学

《生命科学》

2022

m6A demethylase ALKBH5 is required for antibacterial innate defense by intrinsic motivation of neutrophil migration

Yang Liu, R. Song, Lu Zhao, Zhi-Ke Lu, Yi-Ni Li, Xinyi Zhan, Fengjiao Lu, Jiang Yang, Ya-Zhou Niu, Xue-Tao Cao

Signal Transduction and Targeted Therapy

DOI

2022

RNA 2’-O-Methyltransferase Fibrillarin Facilitates Virus Entry Into Macrophages Through Inhibiting Type I Interferon Response

Panpan Li, Yang Liu, R. Song, Lu Zhao, Jiang Yang, Fengjiao Lu, Xue-Tao Cao

Frontiers in Immunology

DOI

2022

IL‐27 signaling negatively regulates FcɛRI‐mediated mast cell activation and allergic response

Xiao-Peng Wan, Yuanyuan Zhang, Huayang Tang, Meng-Yao Li, Tianqi Jiang, Jia He, Chunjing Bao, Jun-Kai Wang, Yinjing Song, P. Xiao, Yang Liu, Li-Hua Lai, Qing-Qing Wang

Journal of Leukocyte Biology

DOI

2020

Correction to: Adenovirus-mediated LIGHT gene modification in murine B-cell lymphoma elicits a potent antitumor effect

Gui-Li Hu, Yang Liu, Hong Li, Dekuang Zhao, Liuqing Yang, Jian-gen Shen, Xue-Jun Hong, Xue-Tao Cao, Qing-Qing Wang

Cellular & Molecular Immunology

DOI

2020

Author Correction: Inducible degradation of lncRNA Sros1 promotes IFN-γ-mediated activation of innate immune responses by stabilizing Stat1 mRNA

He-Nan Xu, Yan Jiang, Xiao-Qing Xu, Xiao-Ping Su, Yang Liu, Yuanwu Ma, Yong Zhao, Zhongyang Shen, Bo Huang, Xue-Tao Cao

Nature Immunology

DOI

2020

Methylation of WWOX gene promotes proliferation of osteosarcoma cells.

Yang Liu, Qingqing Wang, Pengjie Yu, W. Miao, Chuanchuan Liu, Yongqiang Pu, Cheng-Wu Zhang

Journal of B.U.ON. : official journal of the Balkan Union of Oncology

2019

Inducible degradation of lncRNA Sros1 promotes IFN-γ-mediated activation of innate immune responses by stabilizing Stat1 mRNA

He-Nan Xu, Yan Jiang, Xiao-Qing Xu, Xiao-Ping Su, Yang Liu, Yuanwu Ma, Yong Zhao, Zhongyang Shen, Bo Huang, Xue-Tao Cao

Nature Immunology

DOI

2019

MicroRNA-33/33* inhibit the activation of MAVS through AMPK in antiviral innate immunity

Danhui Liu, Qinchun Tan, Jie Zhu, Yuanyuan Zhang, Yue Xue, Yinjing Song, Yang Liu, Qing-Qing Wang, Li-Hua Lai

Cellular & Molecular Immunology

DOI

2019

Fbxw7 increases CCL2/7 in CX3CR1hi macrophages to promote intestinal inflammation.

Jia He, Yinjing Song, Gao-Peng Li, P. Xiao, Yang Liu, Yue Xue, Q. Cao, Xintao Tu, Ting Pan, Zhi-Nong Jiang, Xue-Tao Cao, Li-Hua Lai, Qing-Qing Wang

Journal of Clinical Investigation

DOI

2019

N6-methyladenosine RNA modification–mediated cellular metabolism rewiring inhibits viral replication

Yang Liu, Yuling You, Zhi-Ke Lu, Jiang Yang, Panpan Li, Lun Liu, He-Nan Xu, Ya-Zhou Niu, Xue-Tao Cao

Science

DOI

2018

聚肌胞苷酸及地塞米松诱导的胸腺萎缩及胸腺RLR信号通路表达的比较研究

刘洋，陈颂，龚盛强，葛金文，朱惠斌

《中国免疫学杂志》

2018

干扰素刺激基因及临床意义研究进展

刘洋，刘永亮，葛胜祥

《中国免疫学杂志》

2018

E3 ligase FBXW7 aggravates TMPD-induced systemic lupus erythematosus by promoting cell apoptosis

Zhen-Lu Chong, Chunjing Bao, Jia He, Tian Chen, Lijia Zhong, Gao-Peng Li, Huanle Li, Lutong Fang, Yinjing Song, G. Fu, Xuyan Yang, Li-Hua Lai, Yang Liu, Qing-Qing Wang

Cellular & Molecular Immunology

DOI

2017

免疫性血小板减少症患者外周血调节性T细胞数量减少且血清sLAIR水平升高

刘洋，刘伟伟

《细胞与分子免疫学杂志》

2017

Protective function of interleukin 27 in colitis-associated cancer via suppression of inflammatory cytokines in intestinal epithelial cells

Bijun Cui, Shen Lu, Li-Hua Lai, Yiwei Xie, Jia He, Yue Xue, P. Xiao, Ting Pan, Luoquan Chen, Yang Liu, Xue-Tao Cao, Qing-Qing Wang

Oncoimmunology

DOI

2017

E3 ligase FBXW7 is critical for RIG-I stabilization during antiviral responses

Yinjing Song, Li-Hua Lai, Zhen-Lu Chong, Jia He, Yuanyuan Zhang, Yue Xue, Yiwei Xie, Song-Chang Chen, P. Dong, Luoquan Chen, Zhi-Min Chen, Feng Dai, Xiao-Peng Wan, P. Xiao, Xue-Tao Cao, Yang Liu, Qing-Qing Wang

Nature Communications

DOI

2016

Characteristics and Significance of the Pre-metastatic Niche.

Yang Liu, Xue-Tao Cao

Cancer Cell

DOI

2016

Interleukin 33 in tumor microenvironment is crucial for the accumulation and function of myeloid-derived suppressor cells

Peng-Yu Xiao, Xiao-Peng Wan, Bijun Cui, Yang Liu, Chen-Yang Qiu, Jia-Bing Rong, Mingzhu Zheng, Yinjing Song, Luoquan Chen, Jia He, Qinchun Tan, Xiaojian Wang, X. Shao, Yu-Hua Liu, Xue-Tao Cao, Qing-Qing Wang

Oncoimmunology

DOI

2016

MicroRNA-223 Promotes Type I Interferon Production in Antiviral Innate Immunity by Targeting Forkhead Box Protein O3 (FOXO3)*

Luoquan Chen, Yinjing Song, Li He, Xiao-Peng Wan, Li-Hua Lai, Feng Dai, Yang Liu, Qing-Qing Wang

Journal of Biological Chemistry

DOI

2015

Intratumoral dendritic cells in the anti-tumor immune response

Yang Liu, Xue-Tao Cao

Cellular & Molecular Immunology

DOI

2015

Organotropic metastasis: role of tumor exosomes

Yang Liu, Xue-Tao Cao

Cell Research

DOI

2015

Immunosuppressive cells in tumor immune escape and metastasis

Yang Liu, Xue-Tao Cao

Journal of molecular medicine

DOI

2015

HMGB1 promotes HCC progression partly by downregulating p21 via ERK/c-Myc pathway and upregulating MMP-2

Yan-Min Chen, Cheng-zhao Lin, Yang Liu, Yan Jiang

Tumor Biology

DOI

2014

The origin and function of tumor-associated macrophages

Yang Liu, Xue-Tao Cao

Cellular & Molecular Immunology

DOI

2013

MicroRNA-92a Negatively Regulates Toll-like Receptor (TLR)-triggered Inflammatory Response in Macrophages by Targeting MKK4 Kinase*

Li-Hua Lai, Yinjing Song, Yang Liu, Qing-Yun Chen, Quan-Xiang Han, Wei-Lin Chen, Ting Pan, Yuanyuan Zhang, Xue-Tao Cao, Qing-Qing Wang

Journal of Biological Chemistry

DOI

2012

IFN-γ producing T cells contribute to the increase of myeloid derived suppressor cells in tumor-bearing mice after cyclophosphamide treatment.

Qing-Ming Guo, Zhangchun Lv, Q. Fu, Chaoyi Jiang, Yang Liu, Li-Hua Lai, Qing-Yun Chen, Jian-gen Shen, Qing-Qing Wang

International Immunopharmacology

DOI

2012

Piperine suppresses tumor growth and metastasis in vitro and in vivo in a 4T1 murine breast cancer model

Li-Hua Lai, Q. Fu, Yang Liu, Kai Jiang, Qing-Ming Guo, Qing-Yun Chen, B. Yan, Qingqing Wang, Jian-gen Shen

Acta Pharmacologica Sinica

DOI

2012

MicroRNA-494 Is Required for the Accumulation and Functions of Tumor-Expanded Myeloid-Derived Suppressor Cells via Targeting of PTEN

Yang Liu, Li-Hua Lai, Qing-Yun Chen, Yinjing Song, Sheng Xu, Feng Ma, Xiao-Jian Wang, Jian-Li Wang, Hai Yu, Xue-Tao Cao, Qing-Qing Wang

Journal of Immunology

DOI

2012

Cyclosporine A inhibits breast cancer cell growth by downregulating the expression of pyruvate kinase subtype M2.

Kai Jiang, Baoming He, Li-Hua Lai, Qing-Yun Chen, Yang Liu, Qing-Ming Guo, Qing-Qing Wang

International Journal of Molecular Medicine

DOI

2012

Inducible MicroRNA-223 Down-Regulation Promotes TLR-Triggered IL-6 and IL-1β Production in Macrophages by Targeting STAT3

Qing-Yun Chen, Hui Wang, Yang Liu, Yinjing Song, Li-Hua Lai, Quan-Xiang Han, Xue-Tao Cao, Qing-Qing Wang

PLoS ONE

DOI

2011

MicroRNA‐98 negatively regulates IL‐10 production and endotoxin tolerance in macrophages after LPS stimulation

Yang Liu, Qing-Yun Chen, Yinjing Song, Li-Hua Lai, Jian-Li Wang, Hai Yu, Xue-Tao Cao, Qing-Qing Wang

FEBS Letters

DOI

2010

Adenovirus-mediated LIGHT gene modification in murine B-cell lymphoma elicits a potent antitumor effect

Gui-Li Hu, Yang Liu, Hong Li, Dekuang Zhao, Liuqing Yang, Jian-gen Shen, Xue-Jun Hong, Xue-Tao Cao, Qing-Qing Wang

Cellular & Molecular Immunology

DOI

2009

EBAG9 inducing hyporesponsiveness of T cells promotes tumor growth and metastasis in 4T1 murine mammary carcinoma

Xue-Jun Hong, Yang Liu, Gui-Li Hu, Dekuang Zhao, Jian-gen Shen, F. Shen, Xue-Tao Cao, Qing-Qing Wang

Cancer Science

DOI

精选作品

期刊论文

病毒膜融合蛋白构象转变机制与稳定策略

融合靶向递送与免疫调控的卒中仿生纳米治疗策略（英文）

碱基编辑技术及其在斑马鱼中的开发应用

IL-17信号通路调控机制及其在炎症性疾病中的干预策略研究

BMP9通过Wnt/β-catenin和VEGFa信号诱导前脂肪细胞成骨分化

实现精准癌症免疫疗法的工程化脂质体纳米平台:推进生物医学创新（英文）

蛋白质翻译重编程在肿瘤中的研究进展

HAX1的生物学特性及其与临床疾病关系

脑靶向寡核苷酸药物策略用于衰老相关脑部疾病治疗

碱基编辑器在基因治疗中的潜在安全性风险及解决方案研究进展

m6A demethylase ALKBH5 is required for antibacterial innate defense by intrinsic motivation of neutrophil migration

RNA 2’-O-Methyltransferase Fibrillarin Facilitates Virus Entry Into Macrophages Through Inhibiting Type I Interferon Response

IL‐27 signaling negatively regulates FcɛRI‐mediated mast cell activation and allergic response

Correction to: Adenovirus-mediated LIGHT gene modification in murine B-cell lymphoma elicits a potent antitumor effect

Author Correction: Inducible degradation of lncRNA Sros1 promotes IFN-γ-mediated activation of innate immune responses by stabilizing Stat1 mRNA

Methylation of WWOX gene promotes proliferation of osteosarcoma cells.

Inducible degradation of lncRNA Sros1 promotes IFN-γ-mediated activation of innate immune responses by stabilizing Stat1 mRNA

MicroRNA-33/33* inhibit the activation of MAVS through AMPK in antiviral innate immunity

Fbxw7 increases CCL2/7 in CX3CR1hi macrophages to promote intestinal inflammation.

N6-methyladenosine RNA modification–mediated cellular metabolism rewiring inhibits viral replication

聚肌胞苷酸及地塞米松诱导的胸腺萎缩及胸腺RLR信号通路表达的比较研究

干扰素刺激基因及临床意义研究进展

E3 ligase FBXW7 aggravates TMPD-induced systemic lupus erythematosus by promoting cell apoptosis

免疫性血小板减少症患者外周血调节性T细胞数量减少且血清sLAIR水平升高

Protective function of interleukin 27 in colitis-associated cancer via suppression of inflammatory cytokines in intestinal epithelial cells

E3 ligase FBXW7 is critical for RIG-I stabilization during antiviral responses

Characteristics and Significance of the Pre-metastatic Niche.

Interleukin 33 in tumor microenvironment is crucial for the accumulation and function of myeloid-derived suppressor cells

MicroRNA-223 Promotes Type I Interferon Production in Antiviral Innate Immunity by Targeting Forkhead Box Protein O3 (FOXO3)*

Intratumoral dendritic cells in the anti-tumor immune response

Organotropic metastasis: role of tumor exosomes

Immunosuppressive cells in tumor immune escape and metastasis

HMGB1 promotes HCC progression partly by downregulating p21 via ERK/c-Myc pathway and upregulating MMP-2

The origin and function of tumor-associated macrophages

MicroRNA-92a Negatively Regulates Toll-like Receptor (TLR)-triggered Inflammatory Response in Macrophages by Targeting MKK4 Kinase*

IFN-γ producing T cells contribute to the increase of myeloid derived suppressor cells in tumor-bearing mice after cyclophosphamide treatment.

Piperine suppresses tumor growth and metastasis in vitro and in vivo in a 4T1 murine breast cancer model

MicroRNA-494 Is Required for the Accumulation and Functions of Tumor-Expanded Myeloid-Derived Suppressor Cells via Targeting of PTEN

Cyclosporine A inhibits breast cancer cell growth by downregulating the expression of pyruvate kinase subtype M2.

Inducible MicroRNA-223 Down-Regulation Promotes TLR-Triggered IL-6 and IL-1β Production in Macrophages by Targeting STAT3

MicroRNA‐98 negatively regulates IL‐10 production and endotoxin tolerance in macrophages after LPS stimulation

Adenovirus-mediated LIGHT gene modification in murine B-cell lymphoma elicits a potent antitumor effect

EBAG9 inducing hyporesponsiveness of T cells promotes tumor growth and metastasis in 4T1 murine mammary carcinoma

会议论文

干细胞转录因子SOX2在非小细胞肺癌肿瘤干细胞中直接调控IgG表达