郭增才｜清华大学｜学者主页

期刊论文

2026

Large-Field Mesoscopic Spinning-Disk Confocal Microscopy Enhances Quantitative Fidelity for In Vivo Cerebrovascular and Calcium Sensing

Bingchen Che, Sheng Gao, Yuyou Huang, Jieyu Zhang, Jie Liu, Zengcai V. Guo, Yan He, Hao Xie

Analytical Chemistry

DOI

2025

Intravital observation of neuronal and immune cell dynamics in the developing mammalian brain

Zhen Long, Yongzhen Yu, Chenyi He, Linhe Xu, Yiming Yan, Zhuoru Li, Zengcai V. Guo, Da Mi

Cell

DOI

2025

A sensitive soma-localized red fluorescent calcium indicator for in vivo imaging of neuronal populations at single-cell resolution

Shihao Zhou, Qiyu Zhu, Minho Eom, Shilin Fang, Oksana M. Subach, Ran Chen, Jonnathan Singh Alvarado, Praneel S. Sunkavalli, Yuanping Dong, Yangdong Wang, Jiewen Hu, Hanbin Zhang, Zhiyuan Wang, Xiaoting Sun, Tao Yang, Yu Mu, Young‐Gyu Yoon, Zengcai V. Guo, Fedor V. Subach, Kiryl D. Piatkevich

PLoS Biology

DOI

2024

Long-term mesoscale imaging of 3D intercellular dynamics across a mammalian organ

Yuanlong Zhang, Mingrui Wang, Qiyu Zhu, Yuduo Guo, Bo Liu, Jiamin Li, Xiao Yao, Chui Kong, Yi Zhang, Yuchao Huang, Hai Qi, Jiamin Wu, Zengcai V. Guo, Qionghai Dai

Cell

DOI

2024

A miniaturized mesoscope for the large-scale single-neuron-resolved imaging of neuronal activity in freely behaving mice

Yuanlong Zhang, Lekang Yuan, Qiyu Zhu, Jiamin Wu, Tobias Nöbauer, Rujin Zhang, Guihua Xiao, M W Wang, Hao Xie, Zengcai V. Guo, Qionghai Dai, Alipasha Vaziri

Nature Biomedical Engineering

DOI

2024

Cross-hemispheric communication: Insights on lateralized brain functions

Sebastian Ocklenburg, Zengcai V. Guo

Neuron

DOI

2022

Chronic Ca2+ imaging of cortical neurons with long-term expression of GCaMP-X

Jinli Geng, Yingjun Tang, Zhen Yu, Yunming Gao, Wenxiang Li, Yitong Lu, Bo Wang, Huiming Zhou, Ping Li, Nan Liu, Ping Wang, Yubo Fan, Yaxiong Yang, Zengcai V. Guo, Xiaodong Liu

eLife

DOI

2022

Lateralization of short-term memory in the frontal cortex.

Xin-Xin Yin, Yu Wang, Jiejue Li, Zengcai V. Guo

Cell Reports

DOI

2022

Author response: Chronic Ca2+ imaging of cortical neurons with long-term expression of GCaMP-X

Jinli Geng, Yingjun Tang, Zhen Yu, Yunming Gao, Wenxiang Li, Yitong Lu, Bo Wang, Huiming Zhou, Ping Li, Nan Liu, Ping Wang, Yubo Fan, Yaxiong Yang, Zengcai V. Guo, Xiaodong Liu

DOI

2021

Opposing regulation of short-term memory by basal ganglia direct and indirect pathways that are coactive during behavior

Yingjun Tang, Hongjiang Yang, Xia Chen, Zhouzhou Zhang, Xiao Yao, Xin-Xin Yin, Zengcai V. Guo

bioRxiv

DOI

2021

A cortico-basal ganglia-thalamo-cortical channel underlying short-term memory.

Yu Wang, Xin-Xin Yin, Zhouzhou Zhang, Jiejue Li, Wen-Yu Zhao, Zengcai V. Guo

Neuron

DOI

2021

Multi-Scale Light-Sheet Fluorescence Microscopy for Fast Whole Brain Imaging

Zhouzhou Zhang, Xiao Yao, Xin-Xin Yin, Zhang-Can Ding, Tianyi Huang, Yan Huo, Runan Ji, Hanchuan Peng, Zengcai V. Guo

Frontiers in Neuroanatomy

DOI

2021

Sparse imaging and reconstruction tomography for high-speed high-resolution whole-brain imaging

Han Chen, Tianyi Huang, Yuexin Yang, Xiao Yao, Yan Huo, Yu Wang, Wenyu Zhao, Runan Ji, Hongjiang Yang, Zengcai V. Guo

Cell Reports Methods

DOI

2020

Mapping Functional Connectivity from the Dorsal Cortex to the Thalamus

Yan Huo, Han Chen, Zengcai V. Guo

Neuron

DOI

2019

Spatiotemporal constraints on optogenetic inactivation in cortical circuits

Nuo Li, Su-Su Chen, Zengcai V. Guo, Han Chen, Yan Huo, Hidehiko K. Inagaki, Guang Chen, Courtney Davis, D. Hansel, Cai-Ying Guo, K. Svoboda

eLife

DOI

2019

Author response: Spatiotemporal constraints on optogenetic inactivation in cortical circuits

Nuo Li, Susu Chen, Zengcai V. Guo, Han Chen, Yan Huo, H. Inagaki, Guang Chen, Courtney Davis, David Hansel, Caiying Guo, Karel Svoboda

DOI

2017

Maintenance of persistent activity in a frontal thalamocortical loop

Zengcai V. Guo, Hidehiko K. Inagaki, Kayvon Daie, S. Druckmann, C. Gerfen, K. Svoboda

Nature

DOI

2016

Data related to: A thalamocortical loop underlies selective persistent activity in frontal cortex Zengcai V. Guo, Hidehiko K. Inagaki, Kayvon Daie, Shaul Druckmann, Charles R. Gerfen & Karel Svoboda Nature. 2017.

Zengcai V. Guo, Hidehiko K. Inagaki, Kayvon Daie, S. Druckmann, C. Gerfen, K. Svoboda

DOI

2016

Flow of Information Underlying a Tactile Decision in Mice

Nuo Li, Zengcai V. Guo, Tsai-Wen Chen, K. Svoboda

DOI

2015

A motor cortex circuit for motor planning and movement

Nuo Li, Tsai-Wen Chen, Zengcai V. Guo, C. Gerfen, K. Svoboda

Nature

DOI

2014

Correction: Procedures for Behavioral Experiments in Head-Fixed Mice

Zengcai V. Guo, S. Hires, Nuo Li, D. H. O'Connor, T. Komiyama

PLoS ONE

DOI

2014

Procedures for Behavioral Experiments in Head-Fixed Mice

Zengcai V. Guo, S. Hires, Nuo Li, D. H. O'Connor, T. Komiyama, E. Ophir, D. Huber, C. Bonardi, Karin Morandell, D. Gutnisky, S. Peron, Ning-Long Xu, James Cox, K. Svoboda

PLoS ONE

DOI

2014

Flow of cortical activity underlying a tactile decision in mice.

Zengcai V. Guo, Nuo Li, D. Huber, E. Ophir, D. Gutnisky, Jonathan T. Ting, G. Feng, K. Svoboda

Neuron

DOI

2013

Neural coding during active somatosensation revealed using illusory touch

D. H. O'Connor, S. Hires, Zengcai V. Guo, Nuo Li, Jia-Ning Yu, Qian-Quan Sun, D. Huber, K. Svoboda

Nature Neuroscience

DOI

NeuroResource Mapping Functional Conne ctivity from the Dorsal Cortex to the Thalamus Highlights

Yan Huo, Han Chen, Zengcai V. Guo

预印本

2026

CORAL: A Benchmark for Structure-aware and Brain-wide Neuron Reconstruction in Light Microscopy

Zekang Yang, Jiamin Li, Zhenghua Li, Jiaqi Fan, Zengcai Guo, Xiaolin Hu

arXiv preprint

2026

Cortex-wide single-cell activity mapping in freely moving mice

郭长亮 Guo Changliang，Mian Xie，邱国华，Jian Lu，Yuzhen Liu，Liying Qu，黄园园 Huang Yuanyuan，Zhenran Guo，Jingren Lin，Jingren Lin，Baoyi Zhang，Xuefei Zhang，Junjie Zhao，Xiang Liu，Haochen Long，Jing Ma，Bo Zhou，Xianxin Ye，Pingping Zhao，Jingjie Cao，Zhengan Lin，Zhimiao Zhang，Weijie Deng，Jian Wang，Wei Wu，Junwen Wang，Xiaohong Peng，Shiqun Zhao，Shuai Na，Haoyu Li，Wenhao Liu，Qiang Fu，Zengcai V. Guo，Weisong Zhao，Liangyi Chen

bioRxiv (Cold Spring Harbor Laboratory)

DOI

2026

Posterior parietal cortex guides sensorimotor associative learning by linking sensation to distal action

Qiyu Zhu, Yu Wang, Yuchao Huang, Jieyu Zhang, Xinyi Yang, Angcheng Li, Sixuan Li, Zengcai V. Guo

bioRxiv (Cold Spring Harbor Laboratory)

DOI

2025

Pixel Embedding Method for Tubular Neurite Segmentation

Huayu Fu, Jiamin Li, Haozhi Qu, Xiaolin Hu, Zengcai Guo

arXiv preprint

2025

Task-similarity dependent reconfiguration of compositional modules and geometry in frontal cortex

Xia Chen, Xiao Yao, Xinxin Yin, Zengcai V. Guo

bioRxiv (Cold Spring Harbor Laboratory)

DOI

郭增才

精选作品

期刊论文

Large-Field Mesoscopic Spinning-Disk Confocal Microscopy Enhances Quantitative Fidelity for In Vivo Cerebrovascular and Calcium Sensing

Intravital observation of neuronal and immune cell dynamics in the developing mammalian brain

A sensitive soma-localized red fluorescent calcium indicator for in vivo imaging of neuronal populations at single-cell resolution

Long-term mesoscale imaging of 3D intercellular dynamics across a mammalian organ

A miniaturized mesoscope for the large-scale single-neuron-resolved imaging of neuronal activity in freely behaving mice

Cross-hemispheric communication: Insights on lateralized brain functions

Chronic Ca2+ imaging of cortical neurons with long-term expression of GCaMP-X

Lateralization of short-term memory in the frontal cortex.

Author response: Chronic Ca2+ imaging of cortical neurons with long-term expression of GCaMP-X

Opposing regulation of short-term memory by basal ganglia direct and indirect pathways that are coactive during behavior

A cortico-basal ganglia-thalamo-cortical channel underlying short-term memory.

Multi-Scale Light-Sheet Fluorescence Microscopy for Fast Whole Brain Imaging

Sparse imaging and reconstruction tomography for high-speed high-resolution whole-brain imaging

Mapping Functional Connectivity from the Dorsal Cortex to the Thalamus

Spatiotemporal constraints on optogenetic inactivation in cortical circuits

Author response: Spatiotemporal constraints on optogenetic inactivation in cortical circuits

Maintenance of persistent activity in a frontal thalamocortical loop

Data related to: A thalamocortical loop underlies selective persistent activity in frontal cortex Zengcai V. Guo, Hidehiko K. Inagaki, Kayvon Daie, Shaul Druckmann, Charles R. Gerfen & Karel Svoboda Nature. 2017.

Flow of Information Underlying a Tactile Decision in Mice

A motor cortex circuit for motor planning and movement

Correction: Procedures for Behavioral Experiments in Head-Fixed Mice

Procedures for Behavioral Experiments in Head-Fixed Mice

Flow of cortical activity underlying a tactile decision in mice.

Neural coding during active somatosensation revealed using illusory touch

NeuroResource Mapping Functional Conne ctivity from the Dorsal Cortex to the Thalamus Highlights

预印本

CORAL: A Benchmark for Structure-aware and Brain-wide Neuron Reconstruction in Light Microscopy

Cortex-wide single-cell activity mapping in freely moving mice

Posterior parietal cortex guides sensorimotor associative learning by linking sensation to distal action

Pixel Embedding Method for Tubular Neurite Segmentation

Task-similarity dependent reconfiguration of compositional modules and geometry in frontal cortex

研究方向