李文曦｜重庆医科大学｜学者主页

2024

A Robust ROS Generation and Ferroptotic Lipid Modulation Nanosystem for Mutual Reinforcement of Ferroptosis and Cancer Immunotherapy

Chao Jiang, Wenxi Li, Jie Yan, Xin-Ying Yu, Yu-Zhao Feng, Bei Li, Yuan Liu, Yu-Lun Dai

Advanced Healthcare Materials

DOI

2024

Cuproptotic nanoinducer-driven proteotoxic stress potentiates cancer immunotherapy by activating the mtDNA-cGAS-STING signaling.

Xin-Ying Yu, Bei Li, Jie Yan, Wenxi Li, Hao Tian, Guohao Wang, Songtao Zhou, Yu-Lun Dai

Biomaterials

DOI

2024

Magnesium–Phenolic Nanoeditor Refining Gliomatous T Cells for Metalloimmunotherapy

Wenxi Li, Hao Tian, Zi-Liang Yan, Xin-Ying Yu, Bei Li, Yu-Lun Dai

ACS Nano

DOI

2024

Dual‐Epigenetically Relieving the MYC‐Correlated Immunosuppression via an Advanced Nano‐Radiosensitizer Potentiates Cancer Immuno‐Radiotherapy

Guohao Wang, Jie Yan, Hao Tian, Bei Li, Xin-Ying Yu, Yu-Zhao Feng, Wenxi Li, Songtao Zhou, Yu-Lun Dai

Advances in Materials

DOI

2024

Metal-Phenolic Nanomaterial with Organelle-Level Precision Primes Antitumor Immunity via mtDNA-dependent cGAS-STING Activation.

Hao Tian, Wenxi Li, Guohao Wang, Ye Tian, Jie Yan, Xin-Ying Yu, Zi-Liang Yan, Yu-Zhao Feng, Yunlu Dai

Angewandte Chemie

DOI

2023

Metal-Phenolic Nanomedicines Regulate T-Cell Antitumor Function for Sono-Metabolic Cancer Therapy.

Jie Yan, Wenxi Li, Hao Tian, Bei Li, Xin-Ying Yu, Guohao Wang, Wei Sang, Yun-Lu Dai

ACS Nano

DOI

2023

PhotoPyro‐Induced cGAS‐STING Pathway Activation Enhanced Anti‐Melanoma Immunotherapy via a Manganese‐Coordinated Nanomedicine

Yu-Zhao Feng, Guohao Wang, Wenxi Li, Jie Yan, Xin-Ying Yu, Hao Tian, Bei Li, Yu-Lun Dai

Advanced Healthcare Materials

DOI

2023

Fueling sentinel node via reshaping cytotoxic T lymphocytes with a flex-patch for post-operative immuno-adjuvant therapy

Bei Li, Guohao Wang, Kai Miao, Aiping Zhang, Liangyu Sun, Xiang Yu, J. Lei, Lisi Xie, Jie Yan, Wenxi Li, Chuxia Deng, Yun-Lu Dai

Nature Communications

DOI

2023

Self‐Degradable Nanogels Reshape Immunosuppressive Tumor Microenvironment via Drug Repurposing Strategy to Reactivate Cytotoxic CD8+ T Cells

Hao Tian, Wenxi Li, Guohao Wang, Ye Tian, Jie Yan, Songtao Zhou, Xin-Ying Yu, Bei Li, Yun-Lu Dai

Advancement of science

DOI

2023

A Metal–Phenolic Nanocoordinator Launches Radiotherapeutic Cancer Pyroptosis Through an Epigenetic Mechanism

Guohao Wang, Bei Li, Hao Tian, Lisi Xie, Jie Yan, Wei Sang, Jie Li, Zhan Zhang, Wenxi Li, Yun-Lu Dai

Advanced Functional Materials

DOI

2022

A Metal-Phenolic Nanosensitizer Performs Hydrogen Sulfide-Reprogrammed Oxygen Metabolism for Cancer Radiotherapy Intensification and Immunogenicity.

Jie Li, Lisi Xie, Wei Sang, Wenxi Li, Guohao Wang, Jie Yan, Zhan Zhang, Hao Tian, Qu-Li Fan, Yun-Lu Dai

Angewandte Chemie

DOI

2022

A Triple‐Kill Strategy for Tumor Eradication Reinforced by Metal‐Phenolic Network Nanopumps

Wei Sang, Zhan Zhang, Guohao Wang, Lisi Xie, Jie Li, Wenxi Li, Hao Tian, Yun-Lu Dai

Advanced Functional Materials

DOI

2022

A platinum@polymer-catechol nanobraker enables radio-immunotherapy for crippling melanoma tumorigenesis, angiogenesis, and radioresistance

Wenxi Li, Jie Yan, Hao Tian, Bei Li, Guohao Wang, Wei Sang, Zhan Zhang, Xuanjun Zhang, Yun-Lu Dai

Bioactive Materials

DOI

2022

A Two‐Step Flexible Ultrasound Strategy to Enhance Tumor Radiotherapy via Metal–Phenolic Network Nanoplatform

Ye Tian, Wei Sang, Hao Tian, Lisi Xie, Guohao Wang, Zhan Zhang, Wenxi Li, Yun-Lu Dai

DOI

2022

Manganese-phenolic nanoadjuvant combines sonodynamic therapy with cGAS-STING activation for enhanced cancer immunotherapy

Hao Tian, Guohao Wang, Wei Sang, Lisi Xie, Zhan Zhang, Wenxi Li, Jie Yan, Ye Tian, Jie Li, Bei Li, Yun-Lu Dai

Nano Today

DOI

2022

Phototheranostic Metal-Phenolic Networks with Antiexosomal PD-L1 Enhanced Ferroptosis for Synergistic Immunotherapy.

Lisi Xie, Jie Li, Guohao Wang, Wei Sang, Mengze Xu, Wenxi Li, Jie Yan, Bei Li, Zhan Zhang, Qi Zhao, Zhen Yuan, Qu-Li Fan, Yun-Lu Dai

Journal of the American Chemical Society

DOI

2021

Engineering Radiosensitizer‐Based Metal‐Phenolic Networks Potentiate STING Pathway Activation for Advanced Radiotherapy

Jie Yan, Guohao Wang, Lisi Xie, Hao Tian, Jie Li, Bei Li, Wei Sang, Wenxi Li, Zhan Zhang, Yun-Lu Dai

Advances in Materials

DOI

2021

A “three musketeers” tactic for inclining interferon-γ as a comrade-in-arm to reinforce the synergistic-tumoricidal therapy

Wenxi Li, Lisi Xie, Yi Ju, Zhan Zhang, Bei Li, Jie Li, Wei Sang, Guohao Wang, Hao Tian, Yun-Lu Dai

Nano Reseach

DOI

2021

A metal-polyphenolic nanosystem with NIR-II fluorescence-guided combined photothermal therapy and radiotherapy.

Jie Li, Wenxi Li, Lisi Xie, Wei Sang, Guohao Wang, Zhan Zhang, Bei Li, Hao Tian, Jie Yan, Ye Tian, Zhen-Hua Li, Qu-Li Fan, Lin Yu, Yun-Lu Dai

Chemical Communications

DOI

2021

Engineering a Hydrogen‐Sulfide‐Based Nanomodulator to Normalize Hyperactive Photothermal Immunogenicity for Combination Cancer Therapy

Jie Li, Lisi Xie, Bei Li, Chao Yin, Guohao Wang, Wei Sang, Wenxi Li, Hao Tian, Zhan Zhang, Xuanjun Zhang, Qu-Li Fan, Yun-Lu Dai

Advances in Materials

DOI

2021

A nanounit strategy reverses immune suppression of exosomal PD-L1 and is associated with enhanced ferroptosis

Guohao Wang, Lisi Xie, Bei Li, Wei Sang, Jie Yan, Jie Li, Hao Tian, Wenxi Li, Zhan Zhang, Ye Tian, Yun-Lu Dai

Nature Communications

DOI

2020

Phenolic immunogenic cell death nanoinducer for sensitizing tumor to PD-1 checkpoint blockade immunotherapy.

Lisi Xie, Guohao Wang, Wei Sang, Jie Li, Zhan Zhang, Wenxi Li, Jie Yan, Qi Zhao, Yun-Lu Dai

Biomaterials

DOI

2020

Polyphenol-based Nanomedicine Evokes Immune Activation for Combination Cancer Treatment.

Zhan Zhang, Wei Sang, Lisi Xie, Wenxi Li, Bei Li, Jie Li, Hao Tian, Zhen Yuan, Qi Zhao, Yun-Lu Dai

Angewandte Chemie

DOI

李文曦

精选作品

期刊论文

A Robust ROS Generation and Ferroptotic Lipid Modulation Nanosystem for Mutual Reinforcement of Ferroptosis and Cancer Immunotherapy

Cuproptotic nanoinducer-driven proteotoxic stress potentiates cancer immunotherapy by activating the mtDNA-cGAS-STING signaling.

Magnesium–Phenolic Nanoeditor Refining Gliomatous T Cells for Metalloimmunotherapy

Dual‐Epigenetically Relieving the MYC‐Correlated Immunosuppression via an Advanced Nano‐Radiosensitizer Potentiates Cancer Immuno‐Radiotherapy

Metal-Phenolic Nanomaterial with Organelle-Level Precision Primes Antitumor Immunity via mtDNA-dependent cGAS-STING Activation.

Metal-Phenolic Nanomedicines Regulate T-Cell Antitumor Function for Sono-Metabolic Cancer Therapy.

PhotoPyro‐Induced cGAS‐STING Pathway Activation Enhanced Anti‐Melanoma Immunotherapy via a Manganese‐Coordinated Nanomedicine

Fueling sentinel node via reshaping cytotoxic T lymphocytes with a flex-patch for post-operative immuno-adjuvant therapy

Self‐Degradable Nanogels Reshape Immunosuppressive Tumor Microenvironment via Drug Repurposing Strategy to Reactivate Cytotoxic CD8+ T Cells

A Metal–Phenolic Nanocoordinator Launches Radiotherapeutic Cancer Pyroptosis Through an Epigenetic Mechanism

A Metal-Phenolic Nanosensitizer Performs Hydrogen Sulfide-Reprogrammed Oxygen Metabolism for Cancer Radiotherapy Intensification and Immunogenicity.

A Triple‐Kill Strategy for Tumor Eradication Reinforced by Metal‐Phenolic Network Nanopumps

A platinum@polymer-catechol nanobraker enables radio-immunotherapy for crippling melanoma tumorigenesis, angiogenesis, and radioresistance

A Two‐Step Flexible Ultrasound Strategy to Enhance Tumor Radiotherapy via Metal–Phenolic Network Nanoplatform

Manganese-phenolic nanoadjuvant combines sonodynamic therapy with cGAS-STING activation for enhanced cancer immunotherapy

Phototheranostic Metal-Phenolic Networks with Antiexosomal PD-L1 Enhanced Ferroptosis for Synergistic Immunotherapy.

Engineering Radiosensitizer‐Based Metal‐Phenolic Networks Potentiate STING Pathway Activation for Advanced Radiotherapy

A “three musketeers” tactic for inclining interferon-γ as a comrade-in-arm to reinforce the synergistic-tumoricidal therapy

A metal-polyphenolic nanosystem with NIR-II fluorescence-guided combined photothermal therapy and radiotherapy.

Engineering a Hydrogen‐Sulfide‐Based Nanomodulator to Normalize Hyperactive Photothermal Immunogenicity for Combination Cancer Therapy

A nanounit strategy reverses immune suppression of exosomal PD-L1 and is associated with enhanced ferroptosis

Phenolic immunogenic cell death nanoinducer for sensitizing tumor to PD-1 checkpoint blockade immunotherapy.

Polyphenol-based Nanomedicine Evokes Immune Activation for Combination Cancer Treatment.

研究方向