成子强｜山东农业大学｜学者主页

精选作品

期刊论文

2026

Comparative analysis of viral biological characteristics and pathogenicity of representative prevalent avian reovirus strains from genotypes I to V

Fanrun Meng, Ruiqi Li, Dabin Zhang, Haoze Zhou, Chaonan Zhou, Nan Wang, Yang Wang, Fuqiang Guo, Longying Ding, Feng Lang, Liangyu Yang, Ziqiang Cheng

Virulence

DOI

2026

Recombinant human adenovirus type 5-vectored vaccine expressing avian reovirus σC protein protects against prevalent genotype I avian reovirus in chickens

Xiyao Cui, Zhenrui Song, Defang Zhou, Liangyu Yang, Hongbo Chen, Hui Zhang, Ziqiang Cheng

Poultry Science

DOI

2026

The Janus face of host LncRNA in viral infections: Defender or collaborator?

Longying Ding, Guohua Pei, Ziqiang Cheng

Communications Biology

DOI

2026

Isolation and identification of a highly oncogenic subgroup J avian leukosis virus strain from Chinese black chickens

Shiwei Sun, Xinyue Zhang, Qingjie Liu, Ruixue Xin, Defang Zhou, Longying Ding, Yike Xing, Hongbo Chen, Shuhai He, Ziqiang Cheng

Poultry Science

DOI

2026

A recombinant adenoviral vector vaccine expressing the ORF2 capsid protein confers robust protection against chicken astrovirus infection

Fanrun Meng, Ruiqi Li, Longying Ding, Zhuoyuan Wang, Xiaoyang Liu, Y. C. Song, Feng Lang, Liangyu Yang, Ziqiang Cheng

Veterinary Research

DOI

2025

基于RPA-CRISPR/Cas13a-LFD的鸭星状病毒2型快速可视化检测方法的建立

何书海，陶梦筱，王露遥，周德方，周静，成子强，黄立

《中国兽医学报》

DOI

2025

Establishment of a Rapid and Efficient Method for the Detection of Avian Reovirus Based on RT-RAA-CRISPR/Cas12a Technology

Qi Zheng, Zhiyuan Lu, Huahua Chen, Muzi Li, Haoyi Zhang, Ziqiang Cheng, Jianzhu Liu

Animals

DOI

2025

PERK-eIF2α activation by avian reticuloendotheliosis virus: a dual strategy to suppress apoptosis and aggravate immunosuppression for enhanced replication

Yitong Wang, Yike Xing, Ziqiang Cheng, Wanqing Xu, Chengui Li, Guihua Wang

Poultry Science

DOI

2025

A recombinant human adenovirus type 5 vectored vaccine co-expression of VP1 and VP2 of chicken anemia virus elicits robust protective immune responses

Ruiqi Li, Fanrun Meng, Haoze Zhou, Fuqiang Guo, Tianxing Yan, Hongbo Chen, Feng Lang, Ziqiang Cheng

Poultry Science

DOI

2025

Development of a colloidal gold-based immunochromatographic strip assay for rapid detection of Gyrovirus homsa 1 (GyH1)

Qi Yang, Ziqiang Cheng, Tianxing Yan, Guihua Wang

Journal of Virological Methods

DOI

2025

Avian leukosis virus subgroup J evades innate immunity by activating miR-155 to dually target TRAF3 and STAT1

Xinyue Zhang, Defang Zhou, Jing Zhou, Xiaoyang Liu, Longying Ding, Tianxing Yan, Mengyuan Shi, Shuhai He, Ziqiang Cheng

PLoS Pathogens

DOI

2025

Plus-strand RNA viruses hijack Musashi homolog 1 to shield viral RNA from cytoplasmic ribonuclease degradation

Defang Zhou, Menglu Xu, Qingjie Liu, Ruixue Xin, Gege Cui, Longying Ding, Xiaoyang Liu, Xinyue Zhang, Tianxing Yan, Jing Zhou, Shuhai He, Liangyu Yang, Bin Xiang, Ziqiang Cheng

Journal of Virology

DOI

2025

Chicken anemia virus inhibits hematopoiesis and development of chicken embryo

Tianxing Yan, Yu‐Chen Song, Dabin Zhang, Zhuoyuan Wang, Ruiqi Li, Xinyue Zhang, Bin Xiang, Liangyu Yang, Feng Lang, Dianfeng Chu, Ziqiang Cheng

Poultry Science

DOI

2024

DCLK1 mediated cooperative acceleration of EMT by avian leukosis virus subgroup J and Marek’s disease virus via the Wnt/β-catenin pathway promotes tumor metastasis

Jing Zhou, Defang Zhou, Qian Zhang, Xinyue Zhang, Xiaoyang Liu, Longying Ding, Jing Wen, Xiaoyu Xu, Ziqiang Cheng

Journal of Virology

DOI

2024

Gyrovirus: current status and challenge

Tianxing Yan, Zhuoyuan Wang, Ruiqi Li, Dabin Zhang, Yu‐Chen Song, Ziqiang Cheng

Frontiers in Microbiology

DOI

2024

Specific and Sensitive Visual Proviral DNA Detection of Major Pathogenic Avian Leukosis Virus Subgroups Using CRISPR-Associated Nuclease Cas13a

Qingqing Xu, Yaoyao Zhang, Yashar Sadigh, Na Tang, Jia-qian Chai, Ziqiang Cheng, Yulong Gao, Aijian Qin, Zhiqiang Shen, Yongxiu Yao, Venugopal Nair

Viruses

DOI

2023

禽白血病髓细胞样瘤细胞的鉴别与误诊分析

何书海，张晒，邢一科，成子强

《中国兽医学报》

2023

Research Note: Genetic characterization and pathogenicity of an epidemic variant strain of avian reovirus

Zhenrui Song, Xiaoqing Bi, Fanrun Meng, Qi Qi Yang, Xiangyu Cheng, Defang Zhou, Xinyue Zhang, Longying Ding, Feng Lang, Bing Deng, Kang Wang, Ziqiang Cheng

Poultry Science

DOI

2023

Molecular characteristics and pathogenicity of a novel chicken astrovirus variant

Xiaoqing Bi, Zhenrui Song, Fanrun Meng, Shiwei Sun, Xusheng Du, Mengzan Yang, Defang Zhou, Xiangyu Cheng, Longying Ding, Hengyang Shi, Feng Lang, Huaibiao Luan, Bing Deng, Liangyu Yang, Ziqiang Cheng

Veterinary Research

DOI

2023

miR-155 facilitates the synergistic replication between avian leukosis virus subgroup J and reticuloendotheliosis virus by targeting a dual pathway

Jingwen Xue, Defang Zhou, Jing Zhou, Xusheng Du, Xinyue Zhang, Xiaoyang Liu, Longying Ding, Ziqiang Cheng

Journal of Virology

DOI

2023

Development of a DAS–ELISA for Gyrovirus Homsa1 Prevalence Survey in Chickens and Wild Birds in China

Shicheng Zhang, Jianhao Yang, Defang Zhou, Tianxing Yan, Gen Li, Xiaojing Hao, Qi Qi Yang, Xiangyu Cheng, Hengyang Shi, Qing Liu, Yubao Li, Ziqiang Cheng

Veterinary Sciences

DOI

2023

The Synergy of Chicken Anemia Virus and Gyrovirus Homsa 1 in Chickens

Mengzan Yang, Qi Qi Yang, Xiaoqing Bi, Hengyang Shi, Jianhao Yang, Xiangyu Cheng, Tianxing Yan, Honghai Zhang, Ziqiang Cheng

Viruses

DOI

2023

Molecular characteristics and pathogenicity of a Tibet-origin mutant avian leukosis virus subgroup J isolated from Tibetan chickens in China

Xiangyu Cheng, Jianhao Yang, Xiaoqing Bi, Qi Yang, Defang Zhou, Shicheng Zhang, Longying Ding, Kang Wang, Shuhan Hua, Ziqiang Cheng

Infection Genetics and Evolution

DOI

2023

Molecular evolution analysis of three species gyroviruses in China from 2018 to 2019

Tianxing Yan, Manda Zhao, Yufeng Sun, Shicheng Zhang, Xianwen Zhang, Qing Liu, Yubao Li, Ziqiang Cheng

Virus Research

DOI

2023

Serum amyloid A regulates TLR2/4-mediated IFN-β signaling pathway against Marek's disease virus

Jianhao Yang, Kunmei Yang, Kang Wang, Defang Zhou, Jing Zhou, Xusheng Du, Shenglong Liu, Ziqiang Cheng

Virus Research

DOI

2022

两株不同J亚群禽白血病毒株诱发组织增生病变和细胞因子表达的比较

刘俊宏，赵月，李宏梅，王莹，王沫宇，成子强，邱建华，侯秋玲，郭慧君

《畜牧兽医学报》

2022

网状内皮组织增生病病毒、鸡贫血病毒、大肠杆菌混合感染诱导肉鸡腺胃炎

杜建才，王桂花，杨洁，张贤文，魏宝国，孙玉凤，成子强

《中国兽医杂志》

2022

Immunochromatographic test (ICT) for the detection of antibody against ALV-J

Guihua Wang, Yanming Wang, Ziqiang Cheng

The Thai Journal of Veterinary Medicine

DOI

2022

TRIM25 Participates in the Fibrous Tissue Hyperplasia Induced by ALV-J Infection in Chickens by Targeting 14-3-3σ Protein

Moyu Wang, Junhong Liu, Yue Zhao, Hongmei Li, Jinrun Zhou, Ziqiang Cheng, Jianhua Qiu, Ying Wang, Huijun Guo

Research in Veterinary Science

DOI

2022

Musashi-1 and miR-147 Precursor Interaction Mediates Synergistic Oncogenicity Induced by Co-Infection of Two Avian Retroviruses

Defang Zhou, Longying Ding, Menglu Xu, Xiaoyao Liu, Jingwen Xue, Xinyue Zhang, Xusheng Du, Jing Zhou, Xiyao Cui, Ziqiang Cheng

Cells

DOI

2022

RIOK3-Mediated Akt phosphorylation facilitates synergistic replication of Marek’s disease and reticuloendotheliosis viruses

Xusheng Du, Defang Zhou, Jing Zhou, Jingwen Xue, Ziqiang Cheng

Virulence

DOI

2022

Long read sequencing revealed proventricular virome of broiler chicken with transmission viral proventriculitis

Tianxing Yan, Gen Li, Defang Zhou, Liping Hu, Xiaojing Hao, Ruiqi Li, Guihua Wang, Ziqiang Cheng

BMC Veterinary Research

DOI

2022

Serological investigation of Gyrovirus homsa1 infections in chickens in China

Shicheng Zhang, Shiyu Yuan, Tianxing Yan, Gen Li, Xiaojing Hao, Defang Zhou, Ruiqi Li, Yubao Li, Ziqiang Cheng

BMC Veterinary Research

DOI

2022

TMT-based proteomic analysis reveals integrins involved in the synergistic infection of reticuloendotheliosis virus and avian leukosis virus subgroup J

Xiyao Cui, Xinyue Zhang, Jingwen Xue, Yongxiu Yao, Defang Zhou, Ziqiang Cheng

BMC Veterinary Research

DOI

2022

Marek's Disease Virus and Reticuloendotheliosis Virus Coinfection Enhances Viral Replication and Alters Cellular Protein Profiles

Xusheng Du, Defang Zhou, Jing Zhou, Jingwen Xue, Ziqiang Cheng

Frontiers in Veterinary Science

DOI

2022

Interaction of p10/p27 with macrophage migration inhibitory factor promotes avian leukosis virus subgroup J infection

Kunmei Yang, Jianhao Yang, Defang Zhou, Mingjun Zhu, Xusheng Du, Jing Zhou, Shenglong Liu, Ziqiang Cheng

Veterinary Microbiology

DOI

2022

Marek’s disease virus serine/threonine kinase Us3 facilitates viral replication by targeting IRF7 to block IFN-β production

Xusheng Du, Defang Zhou, Jing Zhou, Jingwen Xue, Guihua Wang, Ziqiang Cheng

Veterinary Microbiology

DOI

2021

蛋鸡J亚型禽白血病病毒与大肠杆菌共感染的诊断

张世成，严天行，袁世玉，成子强

《山东畜牧兽医》

2021

Comparative analysis of the exosomal contents of DF-1 cells infected by ALV-J

Jie Yang, Pingping Zhuang, Ziqiang Cheng, Guihua Wang

Veterinární Medicína

DOI

2021

High-frequency and activation of CD4+CD25+ T cells maintain persistent immunotolerance induced by congenital ALV-J infection

Shuhai He, Gaoying Zheng, Defang Zhou, Li Ping Huang, Jianguo Dong, Ziqiang Cheng

Veterinary Research

DOI

2021

The CCCH-Type Zinc Finger Antiviral Protein Relieves Immunosuppression of T Cells Induced by Avian Leukosis Virus Subgroup J via the NLP–PKC-δ–NFAT Pathway

Mingjun Zhu, Jing Zhou, Defang Zhou, Kunmei Yang, Bin Li, Ziqiang Cheng

Journal of Virology

DOI

2021

Kinetic analysis of pathogenicity and tissue tropism of gyrovirus 3 in experimentally infected chickens

Gen Li, Defang Zhou, Manda Zhao, Qing Liu, Xiaojing Hao, Tianxing Yan, Shiyu Yuan, Shicheng Zhang, Ziqiang Cheng

Veterinary Research

DOI

2021

Cross-species pathogenicity of gyrovirus 3 in experimentally infected chickens and mice

Shiyu Yuan, Tianxing Yan, Libo Huang, Xiaojing Hao, Manda Zhao, Shicheng Zhang, Defang Zhou, Ziqiang Cheng

Veterinary Microbiology

DOI

2020

Regulatory effects of chicken TRIM25 on the replication of ALV-A and the MDA5-mediated type I interferon response

Jinrun Zhou, Junhong Liu, Hongmei Li, Yue Zhao, Ziqiang Cheng, Yan-meng Hou, Huijun Guo

Veterinary Research

DOI

2020

Dynamic changes of TRIM62 distribution in REV infected chickens

Jie Yang, Ling Li, Xiaoman Wang, Ziqiang Cheng, Guihua Wang

The Thai Journal of Veterinary Medicine

DOI

2020

Novel Cyclovirus Identified in Broiler Chickens With Transmissible Viral Proventriculitis in China

Tianxing Yan, Gen Li, Defang Zhou, Xiaoxia Yang, Liping Hu, Ziqiang Cheng

Frontiers in Veterinary Science

DOI

2020

The Distribution and Localization of Collagen Triple Helix Repeat Containing-1 in Naturally and Experimentally Avian Leukosis Virus Subgroup J-Infected Chickens

Yu Pang, Defang Zhou, Jing Zhou, Jingwen Xue, Yiya Wang, Ziqiang Cheng

Frontiers in Veterinary Science

DOI

2020

A novel recombinase polymerase amplification assay for rapid detection of epidemic fowl adenovirus

Ji Zhang, Jie Liu, Da An, Yunhao Fan, Ziqiang Cheng, Yi Tang, Youxiang Diao

Poultry Science

DOI

2020

Avian leukosis virus subgroup J induces B cell anergy mediated by Lyn inhibited BCR signal transduction

Shuhai He, Gaoying Zheng, Xiaoxia Yang, Jianguo Dong, Defang Zhou, Venugopal Nair, Yongxiu Yao, Ziqiang Cheng

Veterinary Microbiology

DOI

2020

Infection of subgroup J avian leukosis induces erythroblasts and lymphoblasts in Chinese local breed chickens

Jie Yang, Ziqiang Cheng, Chengui Li, Guihua Wang

The Thai Journal of Veterinary Medicine

DOI

2020

TRIM62 From Chicken as a Negative Regulator of Reticuloendotheliosis Virus Replication

Ling Li, Dongyan Xu Niu, Jie Yang, Jianmin Bi, Lingjuan Zhang, Ziqiang Cheng, Guihua Wang

Frontiers in Veterinary Science

DOI

2020

Attenuation of a recombinant Marek's disease virus lacking the meq oncogene and evaluation on its immune efficacy against Marek's disease virus

Peng Sun, Ning Cui, Linqing Liu, Shuai Su, Ziqiang Cheng, Ruiai Chen, Yanpeng Li, Zhizhong Cui

Poultry Science

DOI

2020

CCCH-type zinc finger antiviral protein mediates antiviral immune response by activating T cells

Mingjun Zhu, Jing Zhou, Yanfei Liang, Venugopal Nair, Yongxiu Yao, Ziqiang Cheng

Journal of Leukocyte Biology

DOI

2020

Avian leukosis virus subgroup J and reticuloendotheliosis virus coinfection induced TRIM62 regulation of the actin cytoskeleton

Ling Li, Pingping Zhuang, Ziqiang Cheng, Jie Yang, Jianmin Bi, Guihua Wang

Journal of Veterinary Science

DOI

2019

圆圈病毒3型与鸡传染性贫血病毒共感染性腺胃炎的诊断

刁治君，袁世玉，郝小静，冯永胜，张玉利，成子强

《中国家禽》

2019

禽网状内皮组织增生症病毒SNV株人工感染诱导细胞异常增殖研究

何书海，张贤文，郑高颖，邱青瑞，成子强

《中国家禽》

DOI

2019

Interplay between CTHRC1 and the SU protein of avian leukosis virus subgroup J (ALV-J) facilitates viral replication

Yu Pang, Defang Zhou, Jingwen Xue, Jing Zhou, Ya Zhang, Gaoying Zheng, Shiyu Yuan, Yongxiu Yao, Ziqiang Cheng

Virus Research

DOI

2019

Increased Horizontal Transmission of Recombinant Marek’s Disease Virus Due to Reticuloendotheliosis Virus Long Terminal Repeat Is the Major Competitive Advantage of the Virus Being a Prevalent Strain

Shuai Su, Ning Cui, Yanpeng Li, Meng Yu, Ting Zhang, Ziqiang Cheng, Jia-qian Chai, Zhizhong Cui, Ruiai Chen

Frontiers in Microbiology

DOI

2019

TRIM62-mediated restriction of avian leukosis virus subgroup J replication is dependent on the SPRY domain

Ling Li, Weiguo Feng, Ziqiang Cheng, Jie Yang, Jianmin Bi, Xiaoman Wang, Guihua Wang

Poultry Science

DOI

2019

Clonal anergy of CD117+chB6+ B cell progenitors induced by avian leukosis virus subgroup J is associated with immunological tolerance

Shuhai He, Gaoying Zheng, Defang Zhou, Gen Lin Li, Mingjun Zhu, Xusheng Du, Jing Zhou, Ziqiang Cheng

Retrovirology

DOI

2019

Identification and characterization of chicken circovirus from commercial broiler chickens in China

Gen Li, Shiyu Yuan, Tianxing Yan, Hu Shan, Ziqiang Cheng

Transboundary and Emerging Diseases

DOI

2018

miRNA-155在ALV-J与REV共感染中对肌动蛋白细胞骨架通路的影响

李玲，庄萍萍，王小满，周德方，薛静雯，成子强，王桂花

《中国细胞生物学学报》

2018

CCCH-type zinc finger antiviral protein is specifically overexpressed in spleen in response to subgroup J avian leukosis virus infection in chicken

Mingjun Zhu, Jing Zhou, Xiaoqian Ma, Gen Lin Li, Shuhai He, Hao Tang, Yongxiu Yao, Ziqiang Cheng

Research in Veterinary Science

DOI

2018

Outbreak of myelocytomatosis caused by mutational avian leukosis virus subgroup J in China, 2018

Defang Zhou, Jingwen Xue, Ya Zhang, Guihua Wang, Yongsheng Feng, Liping Hu, Yingli Shang, Ziqiang Cheng

Transboundary and Emerging Diseases

DOI

2018

An electrochemical immunosensor based on an etched zeolitic imidazolate framework for detection of avian leukosis virus subgroup J

Chao Liu, Jing Dong, Shixue Ning, Juying Hou, Geoffrey I. N. Waterhouse, Ziqiang Cheng, Shiyun Ai

Microchimica Acta

DOI

2018

Reticuloendotheliosis virus and avian leukosis virus subgroup J synergistically increase the accumulation of exosomal miRNAs

Defang Zhou, Jingwen Xue, Shuhai He, Xusheng Du, Jing Zhou, Chengui Li, Libo Huang, Venugopal Nair, Yongxiu Yao, Ziqiang Cheng

Retrovirology

DOI

2018

Emergence of gyrovirus 3 in commercial broiler chickens with transmissible viral proventriculitis

Gen Li, Shiyu Yuan, HE Meng-lian, Manda Zhao, Xiaojing Hao, Minxun Song, Lingjuan Zhang, Changming Qiao, Libo Huang, Lı Zhang, Chengui Li, Guihua Wang, Ziqiang Cheng

Transboundary and Emerging Diseases

DOI

2018

Preparation and Application of a Monoclonal Antibody Against Chicken TRIM62

Xiaoman Wang, Yongzhen Zhao, Ling Li, Ziqiang Cheng, Guihua Wang

Monoclonal Antibodies in Immunodiagnosis and Immunotherapy

DOI

2018

Synergistic Viral Replication of Marek’s Disease Virus and Avian Leukosis Virus Subgroup J is Responsible for the Enhanced Pathogenicity in the Superinfection of Chickens

Jing Zhou, Guo-Liang Zhao, Xiaoman Wang, Xusheng Du, Shuai Su, Chen-Gui Li, Venugopal Nair, Yongxiu Yao, Ziqiang Cheng

Viruses

DOI

2018

A polyclonal antibody against extracellular loops 1 of chNHE1 blocks avian leukosis virus subgroup J infection

Wei Meng, Defang Zhou, Chengui Li, Guihua Wang, Libo Huang, Ziqiang Cheng

Research in Veterinary Science

DOI

2017

REV感染DF-1细胞分泌外体的生物信息学分析

王小满，庄萍萍，孙霞，杜旭升，王晓宇，成子强，王桂花

《中国细胞生物学学报》

2017

Exosomes carring gag/env of ALV-J possess negative effect on immunocytes

Guihua Wang, Zhenzhen Wang, Pingping Zhuang, Xiaomin Zhao, Ziqiang Cheng

Microbial Pathogenesis

DOI

2017

Degradation of Polysaccharides from Grateloupia filicina and Their Antiviral Activity to Avian Leucosis Virus Subgroup J

Yuhao Sun, Xiaolin Chen, Ziqiang Cheng, Song Liu, Huahua Yu, Xueqin Wang, Pengcheng Li

Marine Drugs

DOI

2017

A novel multi-variant epitope ensemble vaccine against avian leukosis virus subgroup J

Xiaoyu Wang, Defang Zhou, Guihua Wang, Libo Huang, Qiankun Zheng, Chengui Li, Ziqiang Cheng

Vaccine

DOI

2017

Electrochemical immunosensor with nanocellulose-Au composite assisted multiple signal amplification for detection of avian leukosis virus subgroup J

Chao Liu, Jing Dong, Geoffrey I. N. Waterhouse, Ziqiang Cheng, Shiyun Ai

Biosensors and Bioelectronics

DOI

2017

Inhibition of avian tumor virus replication by CCCH-type zinc finger antiviral protein

Mingjun Zhu, Xiaoqian Ma, Xiyao Cui, Jing Zhou, Chengui Li, Libo Huang, Yingli Shang, Ziqiang Cheng

Oncotarget

DOI

2017

Growth retardation induced by avian leukosis virus subgroup J associated with down-regulated Wnt/β-catenin pathway

Weiguo Feng, Defang Zhou, Wei Meng, Gen Lin Li, Pingping Zhuang, Zhifang Pan, Guihua Wang, Ziqiang Cheng

Microbial Pathogenesis

DOI

2016

禽白血病病毒J亚群跨种传播研究

申艳玮，何孟莲，张吉，赵满达，王桂花，成子强

《病毒学报》

2016

网状内皮增生症病毒感染改变外泌体蛋白质组成和免疫调节功能

庄萍萍，王小满，孟薇，李根，成子强，王桂花

《中国细胞生物学学报》

2016

gp85 protein vaccine adjuvanted with silica nanoparticles against ALV-J in chickens

Jia Cheng, Shiyong Wen, Shenghua Wang, Hao Pan, Ziqiang Cheng, Yongxia Liu, Peng Zhao, Jianzhu Liu

Vaccine

DOI

2016

Avian leukosis virus subgroup J induces its receptor--chNHE1 up-regulation

Weiguo Feng, Wei Meng, Liming Cai, Xiyao Cui, Zhifang Pan, Guihua Wang, Ziqiang Cheng

Virology Journal

DOI

2016

Identification of a variant antigenic neutralizing epitope in hypervariable region 1 of avian leukosis virus subgroup J

Minbo Hou, Defang Zhou, Gen Li, Huijun Guo, Jianzhu Liu, Guihua Wang, Qiankun Zheng, Ziqiang Cheng

Vaccine

DOI

2015

Antibody responses induced by recombinant ALV-A gp85 protein vaccine combining with CpG-ODN adjuvant in breeder hens and the protection for their offspring against early infection

Dandan Zhang, Hongmei Li, Zhongsheng Zhang, Shuhong Sun, Ziqiang Cheng, Jianzhu Liu, Peng Zhao, Ren QingYa, Huijun Guo

Antiviral Research

DOI

2015

Synergistic inhibition of avian leukosis virus subgroup J replication by miRNA-embedded siRNA interference of double-target

Rongrong Wei, Xiaoqian Ma, Guihua Wang, Huijun Guo, Jianzhu Liu, Lingxiao Fan, Ziqiang Cheng

Virology Journal

DOI

2014

混养乌鸡和麻鸡J亚群禽白血病病毒感染及变异分析

魏戎蓉，蔡黎明，申艳玮，王言明，成子强

《畜牧兽医学报》

2014

Chicken biliary exosomes enhance CD4+T proliferation and inhibit ALV-J replication in liver

Yue Wang, Guihua Wang, Zhenzhen Wang, Huang‐Ge Zhang, Li Zhang, Ziqiang Cheng

Biochemistry and Cell Biology

DOI

2014

Liposomes containing recombinant gp85 protein vaccine against ALV-J in chickens

Limei Zhang, Dongjie Cai, Xiaona Zhao, Ziqiang Cheng, Huijun Guo, Chunhua Qi, Jianzhu Liu, Ruixue Xu, Peng Zhao, Zhizhong Cui

Vaccine

DOI

2013

禽白血病病毒J亚群自然感染蛋鸡病毒负载、受体表达及致瘤谱关系

蔡黎明，王真真，王言明，申艳玮，魏戎蓉，成子强

《病毒学报》

2013

ALV-Jgp85重组蛋白与免疫佐剂联合接种雏鸡诱导免疫保护的研究

窦文文，李宏梅，成子强，刘建柱，刘海港，井维芳，崔治中，郭慧君

《中国预防兽医学报》

2013

Maternal antibody induced by recombinant gp85 protein vaccine adjuvanted with CpG-ODN protects against ALV-J early infection in chickens

Wenwen Dou, Hongmei Li, Ziqiang Cheng, Peng Zhao, Jianzhu Liu, Zhizhong Cui, Haigang Liu, Weifang Jing, Huijun Guo

Vaccine

DOI

2013

Genetic mutations of avian leukosis virus subgroup J strains extended their host range

Yanwei Shen, Liming Cai, Yanming Wang, Rongrong Wei, Menglian He, Shanhui Wang, Guihua Wang, Ziqiang Cheng

Journal of General Virology

DOI

2013

Identification of two novel multiple recombinant avian leukosis viruses in two different lines of layer chicken

Liming Cai, Yanwei Shen, Guihua Wang, Huijun Guo, Jianzhu Liu, Ziqiang Cheng

Journal of General Virology

DOI

2013

Polyclonal Antibody Against Conserved Peptide in Transmembrane Protein of Avian Leukosis Virus Subgroup J

Guihua Wang, Xiaowei Wang, Qingqing Xu, Ziqiang Cheng

Monoclonal Antibodies in Immunodiagnosis and Immunotherapy

DOI

2013

Avian leukosis virus subgroup J associated with the outbreak of erythroblastosis in chickens in China

Guihua Wang, Yanping Jiang, Linin Yu, Yue Wang, Xiaomin Zhao, Ziqiang Cheng

Virology Journal

DOI

2013

β-cyclodextrin-ferrocene host–guest complex multifunctional labeling triple amplification strategy for electrochemical immunoassay of subgroup J of avian leukosis viruses

Kun Shang, Xindong Wang, Bing Sun, Ziqiang Cheng, Shiyun Ai

Biosensors and Bioelectronics

DOI

2012

J亚群禽白血病病毒跨膜蛋白gp37基因克隆与表达

王晓伟，刘青，徐晴晴，蔡黎明，王真真，王桂花，成子强

《病毒学报》

2012

禽白血病病毒J亚群自然感染商品蛋鸡致瘤性新特征

于琳琳，姜艳萍，王玥，陈洪博，王峰，王晓伟，王桂花，成子强

《畜牧兽医学报》

2012

ALV-J诱发鸡成红细胞白血病的临床病例分析

姜艳萍，王玥，于琳琳，蔡黎明，王真真，徐晴晴，王桂花，成子强

《畜牧兽医学报》

2012

Electrochemical immunoassay for subgroup J of avian leukosis viruses using a glassy carbon electrode modified with a film of poly (3-thiophene boronic acid), gold nanoparticles, graphene and immobilized antibody

Zhenzhen Wang, Kun Shang, Jing Dong, Ziqiang Cheng, Shiyun Ai

Microchimica Acta

DOI

2012

New pathogenetic characters of reticuloendotheliosis virus isolated from Chinese partridge in specific-pathogen-free chickens

Guihua Wang, Yue Wang, Linlin Yu, Yanping Jiang, Jianzhu Liu, Ziqiang Cheng

Microbial Pathogenesis

DOI

2012

New Features of Tumors Induced by Avian Leukosis Virus Subgroup J in Layer Flock

Ziqiang Cheng

Xumu shouyi xuebao

2012

Multifunctional Fe3O4 core/Ni–Al layered double hydroxides shell nanospheres as labels for ultrasensitive electrochemical immunoassay of subgroup J of avian leukosis virus

Kun Shang, Jianying Zhu, Xiaomeng Meng, Ziqiang Cheng, Shiyun Ai

Biosensors and Bioelectronics

DOI

2011

蛋种鸡ALV-J与REV共感染病变新特点

王玥，姜艳萍，于琳琳，王峰，陈洪博，王晓伟，成子强

《畜牧兽医学报》

2011

山东省肉种鸡群三种家禽肿瘤性疾病流行病学调查

张利，张洪海，刘青，刘功振，邱波，刘建柱，郭慧君，成子强

《中国预防兽医学报》

2011

诱发血管瘤型J亚群禽白血病病毒gp85基因的克隆与表达

邱波，刘功振，王晓伟，王峰，陈洪博，成子强

《病毒学报》

2011

禽白血病病毒J亚群诱导蛋鸡群多种肿瘤

陈洪博，于琳琳，姜艳萍，王玥，王峰，王晓伟，王桂花，成子强

《畜牧兽医学报》

2011

The critical time of avian leukosis virus subgroup J-mediated immunosuppression during early stage infection in specific pathogen-free chickens

Feng Wang, Xiaowei Wang, Hongbo Chen, Jianzhu Liu, Ziqiang Cheng

Journal of Veterinary Science

DOI

2011

Epidemic investigation of avian tumor diseases in Shandong area

Ziqiang Cheng

Zhongguo yufang shouyi xuebao

2010

禽白血病病毒J亚群(ALV-J)免疫抑制特性研究

张利，刘青，王晓伟，王峰，陈洪博，成子强

《畜牧兽医学报》

2010

实时荧光定量RT-PCR检测禽白血病病毒J亚群

王峰，刘青，王晓伟，陈洪博，于琳琳，王玥，姜艳萍，成子强

《中国兽医学报》

2010

Influence of REV and ALV-J Co-Infection on Immunologic Function of T Lymphocytes and Histopathology in Broiler Chickens

Huijun Guo, Hongmei Li, Ziqiang Cheng, Jianzhu Liu, Zhizhong Cui

Agricultural Sciences in China

DOI

2010

Tumors Associated with Avian Leukosis Virus Subgroup J in Layer Hens during 2007 to 2009 in China

Ziqiang Cheng, Jianzhu Liu, Zhizhong Cui, Li Zhang

Journal of Veterinary Medical Science

DOI

2009

Mixed Infection of ALV-J and MDV in a Flock of Shandong Free Range Chickens

Ziqiang Cheng

Xumu shouyi xuebao

2008

MDV引起肉鸡动脉粥样硬化机理的研究

杨晓霞，成子强，张红霞，魏国华，王建军

《山东农业大学学报(自然科学版)》

2008

REV感染肉种鸡后动态病理学观察与抗原分布及检测

朱国，刁秀国，成子强，王桂花，孟祥凯，高婷婷

《中国兽医学报》

2008

The Role of Avian leukosis virus Thansmembrane Protein in Membrane Fusion and Immunosuppression

Ziqiang Cheng

Progress in Veterinary Medicine

2007

Occurrence of Reticuloendotheliosis in Chinese Partridge

Ziqiang Cheng, Youfei Shi, Li Zhan, Zhu Guo, Diao Xiuguo, Zhizhong Cui

Journal of Veterinary Medical Science

DOI

2005

肉仔鸡肝细胞癌病理学初报

成子强，张玲娟，张利，刁秀国，王桂花，朱国，崔治中

《中国家禽》

2005

[Emerging of avian leukosis virus subgroup J in a flock of Chinese local breed].

Ziqiang Cheng, Li Zhang, Sidang Liu, Ling‐juan Zhang, Zhizhong Cui

PubMed

2002

禽骨髓细胞瘤病自然病例的病理学研究

赵振华，成子强，顾玉芳，郝永清，杨玉莹，王海燕，高娃，张二芹

《中国兽医科学》

DOI

2002

应用ELISA方法调查鸡骨髓细胞瘤病

成子强，赵心力，郝永清，郭金贵，高娃，顾玉芳，杨玉莹，张二芹，赵振华

《中国家禽》

会议论文

2025

鸡贫血病毒诱导雏鸡再生障碍性贫血机制

严天行，王卓媛，李睿琪，陈守洁，周静，周德方，成子强

《中国畜牧兽医学会兽医病理学分会第二十八次学术研讨会、中国病理生理学会动物病理生理学专业委员会第二十七次学术研讨会、中国实验动物学会实验病理学专业委员会第七次学术研讨会、中国兽医协会兽医病理师分会第六次学术研讨会论文集》

DOI

2019

圆圈病毒3型对鸡和小鼠致病性研究

袁世玉，李根，严天行，郑高颖，薛靖雯，成子强

《中国畜牧兽医学会兽医病理学分会第二十五次学术交流会、中国病理生理学会动物病理学专业委员会第二十四次学术研讨会、中国实验动物学会实验病理学专业委员会第四次学术研讨会、中国兽医病理学家第四次研讨会论文集》

2019

鸡CCCH型锌指抗病毒蛋白通过激活T细胞参与抗病毒免疫

朱明君，周静，梁燕飞，成子强

2019

MDV和REV体外共感染状态下宿主细胞的蛋白组学分析

杜旭升，周静，周德方，成子强

2019

圆圈病毒3型与鸡传染性贫血病毒共感染性腺胃炎病例报告

刁治君，袁世玉，成子强

《中国畜牧兽医学会兽医病理学分会第二十五次学术交流会、中国病理生理学会动物病理学专业委员会第二十四次学术研讨会、中国实验动物学会实验病理学专业委员会第四次学术研讨会、中国兽医病理学家第四次研讨会》

2019

CD4 + CD25 + Treg细胞介导ALV-J诱导免疫耐受的研究

郑高颖，何书海，袁世玉，薛婧雯，成子强

2019

祖B细胞克隆无能与J亚群禽白血病病毒诱导的免疫耐受相关

何书海，郑高颖，周德方，李根，朱明君，成子强

2019

MiR-155介导ALV-J与REV协同复制机制初步研究

薛婧雯，周德方，郑高颖，袁世玉，张心悦，成子强

2019

J亚群禽白血病病毒感染激活双肾上腺素样激酶-1促进DF-1细胞的增殖

周静，周德方，杜旭升，成子强

2019

广西玉林三家鸡场马立克氏病的发生与诊断

张贤文，周德方，成子强

2019

TRIM62抑制禽网赚内皮组织症病毒复制的研究

王桂花，李玲，杨杰，成子强

2018

J亚群禽白血病病毒及其囊膜表面蛋白gp85对禽网状内皮组织增殖病毒复制的影响

张贤文，周德方，成子强

《中国畜牧兽医学会兽医病理学分会第二十四次学术研讨会、中国病理生理学会动物病理生理学专业委员会第二十三次学术研讨会、中国实验动物学会实验病理学专业委员会第三次学术研讨会、中国兽医病理学家第三次学术研讨会》

2018

一种新型环状病毒GyV3病毒的VP1 90-463 和VP1 90-463 -linker-VP2亚单位疫苗的制备

贾梅玉，李根，袁世玉，成子强

2018

J亚群禽白血病病毒与马立克氏病毒协同致病研究

周静，赵国梁，成子强

2018

ALV-J流行株引起的典型髓细胞瘤的病理诊断

庞宇，薛婧雯，郑高颖，张亚，袁世玉，成子强

2018

CD117 + chB6 + B细胞祖细分化障碍是ALV-J先天感染诱导免疫耐受的关键原因

何书海，郑高颖，周德方，李根，朱明君，周静，成子强

《中国畜牧兽医学会兽医病理学分会第二十四次学术研讨会、中国病理生理学会动物病理生理学专业委员会第二十三次学术研讨会、中国实验动物学会实验病理学专业委员会第三次学术研讨会、中国兽医病理学家第三次学术研讨会论文集》

2018

鸡传染性腺胃炎相关病原Gyrovirus 3的分离与鉴定

袁世玉，李根，张亚，成子强

2018

miRNA-155在禽反转录病毒感染中对细胞骨架通路调节作用

李玲，王小满，成子强，王桂花

2017

ALV-J和REV协同感染的exosome途径机制

王桂花，庄萍萍，王小满，成子强

《中国兽医病理学2017年学术研讨会暨兽医病理学分会第九次全国会员代表大会》

2017

鸡TRIM62蛋白组织分布及其抑制ALV-J复制的初步研究

王小满，云骜，周静，李玲，王桂花，成子强

《中国兽医病理学2017年学术研讨会暨兽医病理学分会第九次全国会员代表大会》

2017

鸡CCCH型锌指抗病毒蛋白(chZAP)介导的天然抗病毒免疫

朱明君，马晓倩，周静，黄丽波，李臣贵，王桂花，成子强

《中国兽医病理学2017年学术研讨会暨兽医病理学分会第九次全国会员代表大会》

2016

商品肉鸡中J亚群禽白血病病毒与科氏葡萄球菌、肠炎沙门氏菌的混合感染

李根，韩林臻，杜旭升，成子强

《中国畜牧兽医学会兽医病理学分会、中国病理生理学会动物病理生理专业委员会、中国实验动物学会实验病理学专业委员会2016年学术研讨会》

2016

禽白血病病毒J亚群与鸡败血支原体混合感染的临床病理学观察

周德方，崔熙尧，成子强

《中国畜牧兽医学会2016年学术年会、中国畜牧兽医学会禽病学分会第十八次学术研讨会论文集》

DOI

2015

chNHE1受体Loop1域抗体阻断ALV-J病毒的研究

孟薇，庄萍萍，李根，冯卫国，成子强

《中国畜牧兽医学会兽医病理学分会第二十一次学术研讨会暨中国病理生理学会动物病理生理专业委员会第二十次学术研讨会论文集》

2015

ALV-J劫持exosome途径与exosome携带信息相关性

庄萍萍，成子强，王桂花

《中国畜牧兽医学会兽医病理学分会第二十一次学术研讨会暨中国病理生理学会动物病理生理专业委员会第二十次学术研讨会》

2014

设计和构建嵌合多表位基因作为表位疫苗抵抗ALV-J的感染

徐晴晴，马兴江，王方昆，李宏梅，成子强，赵孝民

《中国畜牧兽医学会2014年学术年会》

2012

ALV-J自然诱发蛋种鸡成红细胞白血病及淋巴瘤

王真真，蔡黎明，徐晴晴，成子强

《2012年中国畜牧兽医学会兽医病理学分会暨中国病理生理学会动物病理生理专业委员会学术研讨会》

2012

禽白血病病毒J亚群与曲霉菌自然感染蛋鸡的致病性观察

蔡黎明，成子强

《2012年中国畜牧兽医学会兽医病理学分会暨中国病理生理学会动物病理生理专业委员会学术研讨会》

2012

外源体在禽白血病病毒诱导免疫抑制中的作用

王真真，蔡黎明，徐晴晴，王桂花，成子强

《2012年中国畜牧兽医学会兽医病理学分会暨中国病理生理学会动物病理生理专业委员会学术研讨会论文集》

2012

临床分离网状内皮增生症病毒的新致病特点研究

王桂花，王玥，于琳琳，姜艳萍，成子强

《2012年中国畜牧兽医学会兽医病理学分会暨中国病理生理学会动物病理生理专业委员会学术研讨会》

2010

实时荧光定量逆转录PCR检测禽白血病病毒J亚群(ALV-J)

王峰，刘青，王晓伟，陈洪博，于琳琳，王玥，姜艳萍，成子强

《中国畜牧兽医学会2010年学术年会——第二届中国兽医临床大会》

2010

感染J亚群禽白血病病毒的蛋鸡群中检测出B亚群禽白血病病毒

刘功振，张洪海，刘青，邱波，王峰，王晓伟，陈洪博，成子强

《中国畜牧兽医学会2010年学术年会——第二届中国兽医临床大会》

2010

J亚群白血病病理学观察及抗原定位

成子强，赵振华，张利，张二芹，高娃

《中国畜牧兽医学会禽病学分会鸡淋巴白血病防控技术研讨会》

2010

J亚群白血病的病理学观察及PCR诊断

成子强，赵振华，张利，高娃，张二芹

《中国畜牧兽医学会禽病学分会鸡淋巴白血病防控技术研讨会》

2010

蛋鸡中发现J亚群白血病与网状内皮增生症自然混合感染

成子强，张玲娟，刘杰，刘思当，赵振华，张利，崔治中

《中国畜牧兽医学会禽病学分会鸡淋巴白血病防控技术研讨会》

2010

REV与ALV-J共感染对肉鸡T淋巴细胞免疫功能与组织病理学的影响

李宏梅，成子强，刘建柱，刘法孝，郭慧君，崔治中

《中国畜牧兽医学会禽病学分会鸡淋巴白血病防控技术研讨会》

2010

地方柴鸡中J亚群禽白血病与马立克氏病的混合感染

张洪海，刘青，邱波，刘功振，成子强

《中国畜牧兽医学会禽病学分会鸡淋巴白血病防控技术研讨会》

2010

鸡感染J亚群禽白血病病毒的免疫抑制机理

商营利，刘思当，丁宝君，肖一红，成子强，孙先明，褚艳丽

《中国畜牧兽医学会禽病学分会鸡淋巴白血病防控技术研讨会》

2010

禽白血病病毒J亚群(ALV-J)基因表达与抗原定位的研究

成子强，刘思当，张利，赵振华

《中国畜牧兽医学会禽病学分会鸡淋巴白血病防控技术研讨会》

2010

禽白血病病毒J亚群(ALV-J)的攻毒试验

成子强，赵振华，张利，高娃

《中国畜牧兽医学会禽病学分会鸡淋巴白血病防控技术研讨会》

2010

禽白血病病毒跨膜蛋白在膜融合及免疫抑制中的作用

刘青，成子强

《中国畜牧兽医学会禽病学分会鸡淋巴白血病防控技术研讨会》

2010

禽骨髓细胞瘤病自然病例的病理学研究

赵振华，成子强，顾玉芳，郝永清，杨玉莹，王海燕，高娃，张二芹

《中国畜牧兽医学会禽病学分会鸡淋巴白血病防控技术研讨会》

2010

商品蛋鸡成髓细胞瘤、血管瘤型J亚群白血病病理学初报

成子强，刘思当，孟祥凯，张洪海，刁秀国，刘青，崔治中

《中国畜牧兽医学会禽病学分会鸡淋巴白血病防控技术研讨会》

2010

中国麻鸡中发现禽J亚群白血病

成子强，张利，刘思当，张玲娟，崔治中

《中国畜牧兽医学会禽病学分会鸡淋巴白血病防控技术研讨会》

2010

蛋种鸡中ALV-J、REV感染及相关疫苗的检测

邱波，张洪海，刘青，刘功振，王峰，陈洪博，王晓伟，成子强

《中国畜牧兽医学会2010年学术年会——第二届中国兽医临床大会论文集(上册)》

2010

J亚群白血病的病理学观察及基因分析

成子强，哈斯阿古拉，张利，赵振华

《中国畜牧兽医学会禽病学分会鸡淋巴白血病防控技术研讨会论文集》

2010

禽白血病病毒J亚群(ALV-J)的血清学调查及PCR诊断

成子强，赵振华，郝永清，赵心力，哈斯阿古拉

《中国畜牧兽医学会禽病学分会鸡淋巴白血病防控技术研讨会论文集》

2010

商品蛋鸡成髓细胞瘤、血管瘤型J亚群白血病病毒特性的研究

孟祥凯，刘青，王海伦，张洪海，邱波，刘功振，成子强

《中国畜牧兽医学会禽病学分会鸡淋巴白血病防控技术研讨会论文集》

2010

应用组织芯片免疫组化法检测ALV-J

张玲娟，刘杰，成子强，王桂花，刁秀国，朱国

《中国畜牧兽医学会禽病学分会鸡淋巴白血病防控技术研讨会论文集》

2009

山东省家禽肿瘤性疾病流行病学调查

成子强，张洪海

《山东畜牧兽医学会禽病学专业委员会成立大会暨第一届禽病学术研讨会》

2009

蛋鸡中出现ALV-J和ALV-B混合感染

刘功振，成子强，张洪海，刘青，邱波，王峰，王晓伟，陈洪博

《中国畜牧兽医学会兽医病理学分会第十六次学术研讨会、中国病理生理学会动物病理生理专业委员会第十五次学术研讨会》

2007

肉种鸡MDV和REV共感染动态病理学与抗原定位的研究

刁秀国，朱国，成子强，王桂花，孟祥凯，高婷婷，崔治中

《第15届世界禽病大会、中国畜牧兽医学会2007年学术年会》

2005

禽白血病病毒J亚群(ALV-J)免疫抑制特性的初步研究

张玲娟，刘杰，成子强，刁秀国，王桂花，朱国

《中国畜牧兽医学会兽医病理学分会第十三次学术讨论会和中国病理生理学会动物病理生理专业委员会第十二次学术讨论会论文集》

预印本

2020

Lyn inhibited BCR signal pathway mediates B-cell anergy induced by avian leukosis virus subgroup J

Shuhai He, Gaoying Zheng, Xiaoxia Yang, Jianguo Dong, Defang Zhou, Venugopal Nair, Yongxiu Yao, Ziqiang Cheng

DOI

2018

ALV-J and REV synergistically activate a new oncogene of KIAA1199 via NF-κB and EGFR signaling regulated by miR-147

Defang Zhou, Jingwen Xue, Pingping Zhuang, Xiyao Cui, Shuhai He, Shuai Su, Guihua Wang, Li Zhang, Chengui Li, Libo Huang, Yingli Shang, Yongxiu Yao, Venugopal Nair, Huang‐Ge Zhang, Ziqiang Cheng

bioRxiv (Cold Spring Harbor Laboratory)

DOI

数据集

2020

Significantly different expressed proteins were quantified by processing MS/MS spectra.

Ziqiang Cheng

Zenodo (CERN European Organization for Nuclear Research)

DOI

研究方向

家禽种源性疾病发病机制与防控禽病毒免疫逃逸及致瘤机制重组/表位疫苗与抗病毒生物药垂直传播疾病净化

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