孙云霞｜武汉大学｜学者主页

2025

益生菌/黑磷纳米片复合材料在肠炎治疗中的应用

姚炜钦，孙云霞，陈巍海，张先正

《高分子学报》

2025

Engineered bacteria with inserted CAR cell membranes for enhanced tumor targeting and biotherapy

Si-Min Zeng, Ke-Wei Chen, Ting Shuang Pan, Yunxia Sun, Jun Feng, Xian‐Zheng Zhang

Nano Today

DOI

2025

Layer‐by‐Layer Deposition of Antigen Peptides on Bifidobacterium for Subintestinal Lymphatic System‐Guided Personalized Tumor Immunotherapy

Zhu Chen, You‐Teng Qin, Qianru Li, Jin‐Lian He, Xin‐Chen Deng, Yun Zhang, Hao‐Dong Yang, Jun Feng, Yunxia Sun, Xian‐Zheng Zhang

Advanced Materials

DOI

2023

Self‐Assembled Copper‐Based Nanoparticles for Glutathione Activated and Enzymatic Cascade‐Enhanced Ferroptosis and Immunotherapy in Cancer Treatment

Wenfang Song, Jin‐Yue Zeng, Ping Ji, Ziyi Han, Yunxia Sun, Xian‐Zheng Zhang

Small

DOI

2023

Ultrasound Activatable Microbombs via Co‐Loading CaO2/Perfluorohexane for Cascade Catalytic Biofilm Disruption and Caries Prevention

Jingmei Guo, Miao‐Deng Liu, Wenlong Lei, Yue Xu, Kaifeng Li, Jian Ling Yu, Yunxia Sun, Cui Huang, Xian‐Zheng Zhang

Advanced Functional Materials

DOI

2023

Colon-targeted bacterial hydrogel for tumor vascular normalization and improved chemotherapy

Wen Li, Jin‐Xuan Fan, Jiyan Qiao, Qi‐Wen Chen, Yunxia Sun, Xian‐Zheng Zhang

Journal of Controlled Release

DOI

2022

Functional Modification of Bacteria during Plasmolysis and Deplasmolysis for Tumor Diagnosis and Treatment

Si-Min Zeng, Diwei Zheng, Ruilin Li, Ze‐Nan Zhuang, Yu Zhang, Yunxia Sun, Xian‐Zheng Zhang

ACS Materials Letters

DOI

2022

A heterogenic membrane-based biomimetic hybrid nanoplatform for combining radiotherapy and immunotherapy against breast cancer

Pei Pan, Xue Dong, Ying Chen, Jing‐Jie Ye, Yunxia Sun, Xian‐Zheng Zhang

Biomaterials

DOI

2022

Vascular disrupting agent-induced amplification of tumor targeting and prodrug activation boosts anti-tumor efficacy

Sheng Hong, Qian‐Xiao Huang, Ping Ji, Xuan Pang, Yunxia Sun, Si‐Xue Cheng, Xian‐Zheng Zhang, Xuesi Chen

Science China Chemistry

DOI

2022

Double Bacteria Synergistic Catalytic Reduction System for Heavy Metal Detoxification Treatment

Yu Zhang, Ting Pan, Chu‐Xin Li, Diwei Zheng, Yunxia Sun, Xian‐Zheng Zhang

Nano Letters

DOI

2022

Research progress in AIE-based crystalline porous materials for biomedical applications

Jin‐Yue Zeng, Xiaoshuang Wang, Yunxia Sun, Xian‐Zheng Zhang

Biomaterials

DOI

2022

Progress of engineered bacteria for tumor therapy

Jin‐Xuan Fan, Mei‐Ting Niu, You‐Teng Qin, Yunxia Sun, Xian‐Zheng Zhang

Advanced Drug Delivery Reviews

DOI

2021

Transformable Spinose Nanodrums with Self‐Supplied H2O2 for Photothermal and Cascade Catalytic Therapy of Tumor

Miao‐Deng Liu, Deng‐Ke Guo, Run‐Yao Zeng, Wenhui Guo, Xinglan Ding, Chu‐Xin Li, Ying Chen, Yunxia Sun, Xian‐Zheng Zhang

Small Methods

DOI

2021

Plasma membrane targeted photodynamic O2 economizer for hypoxic tumor therapy

Guiling Fan, Fu‐An Deng, Xiang Zhou, Lingshan Liu, Jiaqi Huang, Dawei Zhang, Yunxia Sun, Ali Chen, Hong Bo Cheng, Shiying Li

Biomaterials

DOI

2021

Platinum-Doped Prussian Blue Nanozymes for Multiwavelength Bioimaging Guided Photothermal Therapy of Tumor and Anti-Inflammation

Zi-Hao Li, Ying Chen, Yunxia Sun, Xian‐Zheng Zhang

ACS Nano

DOI

2020

Yolk‐Shell Structured Nanoflowers Induced Intracellular Oxidative/Thermal Stress Damage for Cancer Treatment

Miao‐Deng Liu, Deng‐Ke Guo, Run‐Yao Zeng, Jing‐Jie Ye, Shibo Wang, Chu‐Xin Li, Yunxia Sun, Si‐Xue Cheng, Xian‐Zheng Zhang

Advanced Functional Materials

DOI

2020

Recent Advances of Cell Membrane‐Coated Nanomaterials for Biomedical Applications

Wenlong Liu, Mei‐Zhen Zou, Si‐Yong Qin, Yin‐Jia Cheng, Yihan Ma, Yunxia Sun, Xian‐Zheng Zhang

Advanced Functional Materials

DOI

2020

mHealth: A smartphone-controlled, wearable platform for tumour treatment

Runqing Li, Diwei Zheng, Ziyi Han, Tian‐Qiu Xie, Chi Zhang, Jia‐Xin An, Rui Yun Xu, Yunxia Sun, Xian‐Zheng Zhang

Materials Today

DOI

2020

Nitric Oxide Release Device for Remote‐Controlled Cancer Therapy by Wireless Charging

Bin Li, Ping Ji, Si‐Yuan Peng, Pei Pan, Diwei Zheng, Chu‐Xin Li, Yunxia Sun, Xian‐Zheng Zhang

Advanced Materials

DOI

2019

Role of Cholesterol Conjugation in the Antibacterial Photodynamic Therapy of Branched Polyethylenimine-Containing Nanoagents.

Yunxia Sun, Ya-Xuan Zhu, Xiaodong Zhang, Hao-Ran Jia, Yang Xia, Fu-Gen Wu

Langmuir

DOI

2015

ATRP法制备聚(甲基丙烯酸氨乙酯-co-甲基丙烯酸N,N-二乙基氨乙基酯)基因载体

孙云霞，林斌磊，王庆蓉，张先正，卓仁禧

《高分子学报》

2014

A redox-responsive drug delivery system based on RGD containing peptide-capped mesoporous silica nanoparticles

Ze‐Yong Li, Jingjing Hu, Qi Xu, Si Chen, Hui-Zhen Jia, Yunxia Sun, Ren‐Xi Zhuo, Xian‐Zheng Zhang

Journal of Materials Chemistry B

DOI

2012

A linear-dendritic cationic vector for efficient DNA grasp and delivery

Bin Yang, Yunxia Sun, Wen‐Jie Yi, Juan Yang, Chen-wei Liu, Han Lei Cheng, Jun Xiang Feng, Xian‐Zheng Zhang, Ren‐Xi Zhuo

Acta Biomaterialia

DOI

2011

Poly(β-amino amine) cross-linked PEIs as highly efficient gene vectors

Jizhe Deng, Yunxia Sun, Huiyuan Wang, Cao Li, Fuwei Huang, Si‐Xue Cheng, Ren‐Xi Zhuo, Xian‐Zheng Zhang

Acta Biomaterialia

DOI

2010

PEGylated PEI-based biodegradable polymers as non-viral gene vectors

Fuwei Huang, Hui-Yuan Wang, Cao Li, Hua-fen Wang, Yunxia Sun, Jun Feng, Xian‐Zheng Zhang, Ren‐Xi Zhuo

Acta Biomaterialia

DOI

2009

Poly(methyl methacrylate)-graft-oligoamines as low cytotoxic and efficient nonviral gene vectors

Yongqiang Wang, Yunxia Sun, Xinlin Hong, Xian‐Zheng Zhang, Gaoyong Zhang

Molecular BioSystems

DOI

2009

A Potential Targeting Gene Vector Based on Biotinylated Polyethyleneimine/Avidin Bioconjugates

Xuan Zeng, Yunxia Sun, Xian‐Zheng Zhang, Si‐Xue Cheng, Ren‐Xi Zhuo

Pharmaceutical Research

DOI

2009

Properties and Bioapplications of Blended Cellulose and Corn Protein Films

Quanling Yang, Ang Lu, Haisong Qi, Yunxia Sun, Xian‐Zheng Zhang, Lina Zhang

Macromolecular Bioscience

DOI

2009

N -Succinyl-chitosan grafted with low molecular weight polyethylenimine as a serum-resistant gene vector

Bo Lu, Yunxia Sun, Yunqiu Li, Xian‐Zheng Zhang, Ren‐Xi Zhuo

Molecular BioSystems

DOI

2009

Biotinylated disulfide containing PEI/avidin bioconjugate shows specific enhanced transfection efficiency in HepG2 cells

Xuan Zeng, Yunxia Sun, Xian‐Zheng Zhang, Ren‐Xi Zhuo

Organic & Biomolecular Chemistry

DOI

2008

Protamine sulfate/poly(l-aspartic acid) polyionic complexes self-assembled via electrostatic attractions for combined delivery of drug and gene

Han Lei Cheng, Yongyong Li, Xuan Zeng, Yunxia Sun, Xian‐Zheng Zhang, Ren‐Xi Zhuo

Biomaterials

DOI

2008

Supramolecular Structure and Properties of High Strength Regenerated Cellulose Films

Shilin Liu, Lina Zhang, Yunxia Sun, Yi Hong Lin, Xian‐Zheng Zhang, Yoshiharu Nishiyama

Macromolecular Bioscience

DOI

2008

The influence of RGD addition on the gene transfer characteristics of disulfide-containing polyethyleneimine/DNA complexes

Yunxia Sun, Xuan Zeng, Qingfei Meng, Xian‐Zheng Zhang, Si‐Xue Cheng, Ren‐Xi Zhuo

Biomaterials

DOI

2008

Homogeneous Quaternization of Cellulose in NaOH/Urea Aqueous Solutions as Gene Carriers

Yongbo Song, Yunxia Sun, Xian‐Zheng Zhang, Jinping Zhou, Lina Zhang

Biomacromolecules

DOI

2008

Novel Thermoresponsive Nonviral Gene Vector: P(NIPAAm-co-NDAPM)-b-PEI with Adjustable Gene Transfection Efficiency

Han Lei Cheng, Jingling Zhu, Yunxia Sun, Si‐Xue Cheng, Xian‐Zheng Zhang, Ren‐Xi Zhuo

Bioconjugate Chemistry

DOI

2008

Thermosensitive P(NIPAAm-co-PAAc-co-HEMA) nanogels conjugated with transferrin for tumor cell targeting delivery

Changyun Quan, Yunxia Sun, Han Lei Cheng, Si‐Xue Cheng, Xian‐Zheng Zhang, Ren‐Xi Zhuo

Nanotechnology

DOI

2008

Synthesis of (Dex-HMDI)-g-PEIs as effective and low cytotoxic nonviral gene vectors

Yunxia Sun, Xiao Wang, Si‐Xue Cheng, Xian‐Zheng Zhang, Ren‐Xi Zhuo

Journal of Controlled Release

DOI

2008

Biodegradable and pH-Sensitive Hydrogels for Cell Encapsulation and Controlled Drug Release

Dequn Wu, Yunxia Sun, Xiaoding Xu, Si‐Xue Cheng, Xian‐Zheng Zhang, Ren‐Xi Zhuo

Biomacromolecules

DOI

2007

A low‐toxic and efficient gene vector: Carboxymethyl dextran‐graft‐polyethylenimine

Yunxia Sun, Xian‐Zheng Zhang, Han Lei Cheng, Si‐Xue Cheng, Ren‐Xi Zhuo

Journal of Biomedical Materials Research Part A

DOI

精选作品

期刊论文

益生菌/黑磷纳米片复合材料在肠炎治疗中的应用

Engineered bacteria with inserted CAR cell membranes for enhanced tumor targeting and biotherapy

Layer‐by‐Layer Deposition of Antigen Peptides on Bifidobacterium for Subintestinal Lymphatic System‐Guided Personalized Tumor Immunotherapy

Self‐Assembled Copper‐Based Nanoparticles for Glutathione Activated and Enzymatic Cascade‐Enhanced Ferroptosis and Immunotherapy in Cancer Treatment

Ultrasound Activatable Microbombs via Co‐Loading CaO2/Perfluorohexane for Cascade Catalytic Biofilm Disruption and Caries Prevention

Colon-targeted bacterial hydrogel for tumor vascular normalization and improved chemotherapy

Functional Modification of Bacteria during Plasmolysis and Deplasmolysis for Tumor Diagnosis and Treatment

A heterogenic membrane-based biomimetic hybrid nanoplatform for combining radiotherapy and immunotherapy against breast cancer

Vascular disrupting agent-induced amplification of tumor targeting and prodrug activation boosts anti-tumor efficacy

Double Bacteria Synergistic Catalytic Reduction System for Heavy Metal Detoxification Treatment

Research progress in AIE-based crystalline porous materials for biomedical applications

Progress of engineered bacteria for tumor therapy

Transformable Spinose Nanodrums with Self‐Supplied H2O2 for Photothermal and Cascade Catalytic Therapy of Tumor

Plasma membrane targeted photodynamic O2 economizer for hypoxic tumor therapy

Platinum-Doped Prussian Blue Nanozymes for Multiwavelength Bioimaging Guided Photothermal Therapy of Tumor and Anti-Inflammation

Yolk‐Shell Structured Nanoflowers Induced Intracellular Oxidative/Thermal Stress Damage for Cancer Treatment

Recent Advances of Cell Membrane‐Coated Nanomaterials for Biomedical Applications

mHealth: A smartphone-controlled, wearable platform for tumour treatment

Nitric Oxide Release Device for Remote‐Controlled Cancer Therapy by Wireless Charging

Role of Cholesterol Conjugation in the Antibacterial Photodynamic Therapy of Branched Polyethylenimine-Containing Nanoagents.

ATRP法制备聚(甲基丙烯酸氨乙酯-co-甲基丙烯酸N,N-二乙基氨乙基酯)基因载体

A redox-responsive drug delivery system based on RGD containing peptide-capped mesoporous silica nanoparticles

A linear-dendritic cationic vector for efficient DNA grasp and delivery

Poly(β-amino amine) cross-linked PEIs as highly efficient gene vectors

PEGylated PEI-based biodegradable polymers as non-viral gene vectors

Poly(methyl methacrylate)-graft-oligoamines as low cytotoxic and efficient nonviral gene vectors

A Potential Targeting Gene Vector Based on Biotinylated Polyethyleneimine/Avidin Bioconjugates

Properties and Bioapplications of Blended Cellulose and Corn Protein Films

N -Succinyl-chitosan grafted with low molecular weight polyethylenimine as a serum-resistant gene vector

Biotinylated disulfide containing PEI/avidin bioconjugate shows specific enhanced transfection efficiency in HepG2 cells

Protamine sulfate/poly(l-aspartic acid) polyionic complexes self-assembled via electrostatic attractions for combined delivery of drug and gene

Supramolecular Structure and Properties of High Strength Regenerated Cellulose Films

The influence of RGD addition on the gene transfer characteristics of disulfide-containing polyethyleneimine/DNA complexes

Homogeneous Quaternization of Cellulose in NaOH/Urea Aqueous Solutions as Gene Carriers

Novel Thermoresponsive Nonviral Gene Vector: P(NIPAAm-co-NDAPM)-b-PEI with Adjustable Gene Transfection Efficiency

Thermosensitive P(NIPAAm-co-PAAc-co-HEMA) nanogels conjugated with transferrin for tumor cell targeting delivery

Synthesis of (Dex-HMDI)-g-PEIs as effective and low cytotoxic nonviral gene vectors

Biodegradable and pH-Sensitive Hydrogels for Cell Encapsulation and Controlled Drug Release

A low‐toxic and efficient gene vector: Carboxymethyl dextran‐graft‐polyethylenimine

会议论文

新型高效低毒基因载体的研究

基因治疗产品安全性评价的特殊性

研究方向