生秀梅｜江苏大学｜学者主页

2026

噬菌体基因工程技术与应用研究进展

焦耀萱，李敏，屈昕雅，刘恬伶，生秀梅，周晓祥

《生物技术进展》

DOI

2024

Vi capsular polysaccharide of Salmonella enterica serovar Typhi disturbs autophagy to increase intracellular survival in macrophages.

Ying Zhang, Zhong-Yi Xie, Fan-Fan Yang, Lina Zhan, Zuowei Zhang, Xiumei Sheng, Lingchao Xia

Microbial Pathogenesis

DOI

2022

Acacetin antagonized lipotoxicity in pancreatic β-cells via ameliorating oxidative stress and endoplasmic reticulum stress

Ning Wang, Qing Gao, Jie Shi, Chen Yulan, Weimeng Ji, Xiumei Sheng, Rui Zhang

Molecular Biology Reports

DOI

2021

不同条件下伤寒沙门菌Vi荚膜多糖的表达调控研究

尹芬芬，谢中艺，杨帆帆，生秀梅，黄新祥，张盈

《微生物与感染》

2021

伤寒沙门菌激活TRAIL信号通路促进巨噬细胞凋亡

尹芬芬，杨帆帆，谢中艺，王雨柔，黄新祥，生秀梅，张盈

《华中师范大学学报(自然科学版)》

DOI

2020

Regulation of Autophagy by Glycolysis in Cancer

Ying Chu, Yi Chang, Wei Lü, Xiumei Sheng, Shengjun Wang, Huaxi Xu, Jie Ma

Cancer Management and Research

DOI

2020

WD Repeat Domain 77 Protein Regulates Translation of E2F1 and E2F3 mRNA

Mahmood Anber Altayyar, Xiumei Sheng, Zhengxin Wang

Molecular and Cellular Biology

DOI

2019

胶质瘤致病相关蛋白1对肺癌A549细胞生长及分化的影响

生秀梅，黄新祥，王正新

《郑州大学学报(医学版)》

DOI

2019

医院耐碳青霉烯肠杆菌产NDM-1型碳青霉烯酶情况分析

张慧，生秀梅，舒扬，向敏，阴晴

《广东医学》

DOI

2019

LncRNAs: The Regulator of Glucose and Lipid Metabolism in Tumor Cells

Wei Lü, Fenghua Cao, Sheng-Jun Wang, Xiumei Sheng, Jie Ma

Frontiers in Oncology

DOI

2019

QsvR integrates into quorum sensing circuit to control Vibrio parahaemolyticus virulence

Yiquan Zhang, Linghui Hu, Yue Qiu, George Osei‐Adjei, Hao Tang, Ying Zhang, Rui Zhang, Xiumei Sheng, Shungao Xu, Wenhui Yang, Huiying Yang, Zhe Yin, Ruifu Yang, Xinxiang Huang, Dongsheng Zhou

Environmental Microbiology

DOI

2018

伤寒沙门菌非编码RNA AsrC表达特性及功能初步研究

张盈，张晓磊，詹莉芳，张琪，生秀梅，黄新祥

《华中师范大学学报(自然科学版)》

2018

Autoregulation of ToxR and Its Regulatory Actions on Major Virulence Gene Loci in Vibrio parahaemolyticus

Yiquan Zhang, Lingfei Hu, George Osei‐Adjei, Ying Zhang, Wenhui Yang, Zhe Yin, Renyun Lu, Xiumei Sheng, Ruifu Yang, Xinxiang Huang, Dongsheng Zhou

Frontiers in Cellular and Infection Microbiology

DOI

2017

多黏菌素B刺激下伤寒沙门菌mig-14基因的表达特性

陈龙，杨璐璐，李敏，殷灵莉，徐顺高，黄新祥，生秀梅

《江苏大学学报(医学版)》

2016

pGL3-4×PRE-E4-luc报告基因质粒的构建及在p44信号通路中的应用鉴定

生秀梅，WANG Zhengxin

《华中师范大学学报(自然科学版)》

2016

伤寒沙门菌小RNA T64的功能

徐慧，袁一航，陆仁飞，刘娟利，张盈，生秀梅，徐顺高，黄新祥

《江苏大学学报(医学版)》

2016

glipr1基因的原核表达及多克隆抗体制备

生秀梅，陈龙，王正新

《安徽医科大学学报》

2016

ErbB3/Her3基因重组慢病毒的构建及应用

生秀梅，王正新

《郑州大学学报(医学版)》

2016

BTG2基因重组慢病毒载体的构建及其在肺癌A549细胞中的表达与功能

生秀梅，王正新

《福建医科大学学报》

2016

Protein arginine methyltransferase 5 regulates multiple signaling pathways to promote lung cancer cell proliferation

Xiumei Sheng, Zhengxin Wang

BMC Cancer

DOI

2016

GLI pathogenesis-related 1 functions as a tumor-suppressor in lung cancer

Xiumei Sheng, Nathan J. Bowen, Zhengxin Wang

Molecular Cancer

DOI

2015

伤寒沙门菌外膜孔道蛋白ompC、ompF缺陷株的制备及其耐药性

汪伟伟，夏歆，王静瑜，张桂红，陈龙，黄新祥，生秀梅

《江苏大学学报(医学版)》

2015

5′-UTR of malS Increases the Invasive Capacity of Salmonella Enterica Serovar Typhi by Influencing the Expression of Bax

Mingyu Gong, Shungao Xu, Yue Jin, Ying Zhang, Isaac Dadzie, Xiaolei Zhang, Zhexin Wang, Yunxia Zhu, Bin Ni, Xiumei Sheng, Xinxiang Huang

Future Microbiology

DOI

2014

伤寒沙门菌Mig-14蛋白部分密码子优化后的表达及多克隆抗体制备

张红，生秀梅，徐顺高，黄新祥，许化溪

《华中师范大学学报(自然科学版)》

2014

Identification and characterization of a cis antisense RNA of the parC gene encoding DNA topoisomerase IV of Salmonella enterica serovar Typhi

Isaac Dadzie, Bin Ni, Mingyu Gong, Ying Zhang, Haifang Zhang, Xiumei Sheng, Shungao Xu, Xinxiang Huang

Research in Microbiology

DOI

2014

Design of a comprehensive biochemistry and molecular biology experiment: Phase variation caused by recombinational regulation of bacterial gene expression

Xiumei Sheng, Shungao Xu, Renyun Lu, Isaac Dadzie, Xueyi Zhang, Haifang Zhang, Hui‐Fang Wang, Zheng Qiao, Xinxiang Huang

Biochemistry and Molecular Biology Education

DOI

2013

伤寒沙门菌高渗诱导基因osmY的克隆表达与多克隆抗体的制备

翁晓琴，张红，詹莉芳，张晓磊，生秀梅，徐顺高，黄新祥

《江苏大学学报(医学版)》

2013

Identification and Characterization of a Cis-Encoded Antisense RNA Associated with the Replication Process of Salmonella enterica Serovar Typhi

Isaac Dadzie, Shungao Xu, Bin Ni, Xiaolei Zhang, Haifang Zhang, Xiumei Sheng, Huaxi Xu, Xinxiang Huang

PLoS ONE

DOI

2012

伤寒沙门菌核糖核酸酶G对胞内非编码RNA T3956水平的影响

王菲，孟彦辰，詹莉芳，张晓磊，张海方，生秀梅，徐顺高，黄新祥

《江苏大学学报(医学版)》

2012

OsmY缺失对伤寒沙门菌在高渗应激早期基因表达的影响

孟彦辰，王菲，杜鸿，翁晓琴，张海方，生秀梅，徐顺高，黄新祥

《江苏大学学报(医学版)》

2012

伤寒沙门菌virK和mig-14基因在拮抗多黏菌素B杀伤作用中的差异

夏秋风，生秀梅，徐顺高，黄新祥

《江苏大学学报(医学版)》

2012

H:z66抗体应激后伤寒沙门菌fliG基因缺陷株与野生株基因表达的差异

张晓磊，生秀梅，张海方，徐顺高，黄新祥

《江苏大学学报(医学版)》

2011

OmpR May Regulate the Putative YehU/YehT Two-Component System in Salmonella enterica serovar Typhi Under Hypotonic Growth Condition

Haifang Zhang, Hong Du, Xiaolan Ji, Bin Ni, Linxiang Mao, Shungao Xu, Xiumei Sheng, Huaxi Xu, Xinxiang Huang

Current Microbiology

DOI

2011

Molecular Characterization of a Functional Type VI Secretion System in Salmonella enterica serovar Typhi

Min Wang, Zhe Luo, Hong Du, Shungao Xu, Bin Ni, Haifang Zhang, Xiumei Sheng, Huaxi Xu, Xinxiang Huang

Current Microbiology

DOI

2010

伤寒沙门菌调节因子UhpA的功能研究

李君辉，罗哲，谢新民，李安平，杜鸿，生秀梅，黄新祥

《江苏大学学报(医学版)》

2010

细菌小RNA的研究

生秀梅，徐顺高，张海方，黄新祥，许化溪

《生命的化学》

2010

OmpR与PhoP高渗应激下交叉调节伤寒沙门菌基因表达

生秀梅，徐顺高，张海方，许化溪，黄新祥

《华中师范大学学报(自然科学版)》

2010

抗H:z66抗体诱导z66+伤寒沙门菌鞭毛相变换特点的探讨

张海方，黄新祥，张晓磊，倪斌，生秀梅，徐顺高，许化溪

《苏州大学学报(医学版)》

2010

RpoE may Promote Flagellar Gene Expression in Salmonella enterica Serovar Typhi Under Hyperosmotic Stress

Hong Du, Xiumei Sheng, Haifang Zhang, Xin Zou, Bin Ni, Shungao Xu, Xue‐Ming Zhu, Huaxi Xu, Xinxiang Huang

Current Microbiology

DOI

2010

Expression of fljB: z66 on a linear plasmid of Salmonella enterica serovar typhi is dependent on FliA and FlhDC and regulated by OmpR

Shungao Xu, Xin Zou, Xiumei Sheng, Haifang Zhang, Lingxiang Mao, Hong Du, Huaxi Xu, Xinxiang Huang

Brazilian Journal of Microbiology

DOI

2010

Expression of tviA is transiently repressed by Hfq in Salmonella enterica serovar Typhi at hyperosmotic stress

Xinmin Xie, Anping Li, Hong Du, Xiumei Sheng, Haifang Zhang, Shungao Xu, Xinxiang Huang

Microbial Pathogenesis

DOI

2009

伤寒沙门菌基因组DNA芯片的制备与基因表达谱分析应用

生秀梅，黄新祥，茅凌翔，朱超望，徐顺高，张海方，许化溪，刘秀梅

《生物化学与生物物理进展》

2009

伤寒沙门菌基因组DNA芯片基因表达谱分析技术的建立与优化

生秀梅，黄新祥，徐顺高，张海方，许化溪

《江苏大学学报(医学版)》

2009

伤寒沙门菌鞭毛素基因fljB:z66的克隆表达及其多克隆抗体的制备

张海方，高宇琳，黄新祥，生秀梅，徐顺高，许化溪

《江苏大学学报(医学版)》

2009

PmrA对伤寒沙门菌高渗应激后期基因表达调节初探

高宇琳，张海方，邹昕，杜鸿，夏秋风，生秀梅，徐顺高，黄新祥

《江苏大学学报(医学版)》

2009

Global transcriptional response ofSalmonella enterica serovar Typhi to anti-z66 antiserum

Haifang Zhang, Xiumei Sheng, Shungao Xu, Yulin Gao, Hong Du, Junrong Li, Huaxi Xu, Xinxiang Huang

FEMS Microbiology Letters

DOI

精选作品

期刊论文

噬菌体基因工程技术与应用研究进展

Vi capsular polysaccharide of Salmonella enterica serovar Typhi disturbs autophagy to increase intracellular survival in macrophages.

Acacetin antagonized lipotoxicity in pancreatic β-cells via ameliorating oxidative stress and endoplasmic reticulum stress

不同条件下伤寒沙门菌Vi荚膜多糖的表达调控研究

伤寒沙门菌激活TRAIL信号通路促进巨噬细胞凋亡

Regulation of Autophagy by Glycolysis in Cancer

WD Repeat Domain 77 Protein Regulates Translation of E2F1 and E2F3 mRNA

胶质瘤致病相关蛋白1对肺癌A549细胞生长及分化的影响

医院耐碳青霉烯肠杆菌产NDM-1型碳青霉烯酶情况分析

LncRNAs: The Regulator of Glucose and Lipid Metabolism in Tumor Cells

QsvR integrates into quorum sensing circuit to control Vibrio parahaemolyticus virulence

伤寒沙门菌非编码RNA AsrC表达特性及功能初步研究

Autoregulation of ToxR and Its Regulatory Actions on Major Virulence Gene Loci in Vibrio parahaemolyticus

多黏菌素B刺激下伤寒沙门菌mig-14基因的表达特性

pGL3-4×PRE-E4-luc报告基因质粒的构建及在p44信号通路中的应用鉴定

伤寒沙门菌小RNA T64的功能

glipr1基因的原核表达及多克隆抗体制备

ErbB3/Her3基因重组慢病毒的构建及应用

BTG2基因重组慢病毒载体的构建及其在肺癌A549细胞中的表达与功能

Protein arginine methyltransferase 5 regulates multiple signaling pathways to promote lung cancer cell proliferation

GLI pathogenesis-related 1 functions as a tumor-suppressor in lung cancer

伤寒沙门菌外膜孔道蛋白ompC、ompF缺陷株的制备及其耐药性

5′-UTR of malS Increases the Invasive Capacity of Salmonella Enterica Serovar Typhi by Influencing the Expression of Bax

伤寒沙门菌Mig-14蛋白部分密码子优化后的表达及多克隆抗体制备

Identification and characterization of a cis antisense RNA of the parC gene encoding DNA topoisomerase IV of Salmonella enterica serovar Typhi

Design of a comprehensive biochemistry and molecular biology experiment: Phase variation caused by recombinational regulation of bacterial gene expression

伤寒沙门菌高渗诱导基因osmY的克隆表达与多克隆抗体的制备

Identification and Characterization of a Cis-Encoded Antisense RNA Associated with the Replication Process of Salmonella enterica Serovar Typhi

伤寒沙门菌核糖核酸酶G对胞内非编码RNA T3956水平的影响

OsmY缺失对伤寒沙门菌在高渗应激早期基因表达的影响

伤寒沙门菌virK和mig-14基因在拮抗多黏菌素B杀伤作用中的差异

H:z66抗体应激后伤寒沙门菌fliG基因缺陷株与野生株基因表达的差异

OmpR May Regulate the Putative YehU/YehT Two-Component System in Salmonella enterica serovar Typhi Under Hypotonic Growth Condition

Molecular Characterization of a Functional Type VI Secretion System in Salmonella enterica serovar Typhi

伤寒沙门菌调节因子UhpA的功能研究

细菌小RNA的研究

OmpR与PhoP高渗应激下交叉调节伤寒沙门菌基因表达

抗H:z66抗体诱导z66+伤寒沙门菌鞭毛相变换特点的探讨

RpoE may Promote Flagellar Gene Expression in Salmonella enterica Serovar Typhi Under Hyperosmotic Stress

Expression of fljB: z66 on a linear plasmid of Salmonella enterica serovar typhi is dependent on FliA and FlhDC and regulated by OmpR

Expression of tviA is transiently repressed by Hfq in Salmonella enterica serovar Typhi at hyperosmotic stress

伤寒沙门菌基因组DNA芯片的制备与基因表达谱分析应用

伤寒沙门菌基因组DNA芯片基因表达谱分析技术的建立与优化

伤寒沙门菌鞭毛素基因fljB:z66的克隆表达及其多克隆抗体的制备

PmrA对伤寒沙门菌高渗应激后期基因表达调节初探

Global transcriptional response ofSalmonella enterica serovar Typhi to anti-z66 antiserum

会议论文

RpoE与伤寒沙门菌高渗应激下的基因表达调节

伤寒沙门菌mig-14基因作为调节因子的功能研究

伤寒沙门菌鞭毛相变换前后线性质粒结构差异分析

伤寒沙门菌调节因子OmpR的原核表达与功能研究

伤寒沙门菌鞭毛介导的基因表达调节作用

T-bet、GATA3及相关因子的表达与胃癌及转移的相关性研究

不同渗透压环境下伤寒沙门菌z66鞭毛抗原基因的表达调控