孙昊昱｜复旦大学｜学者主页

2026

Identify key environmental factors and neglected genetic SNPs associated with obsessive-compulsive disorder by two-sample multivariate Mendelian randomization analysis

Yongheng Wang, Weiye Qian, Haoyu Sun, Juan Zhao, Mingdao Mu, Zhiyuan Yang

Journal Of Affective Disorders，Vol. 3920

2026

Spiky Nanoparticle‐Gel Composite for Efficient Intravesical Botulinum Toxin A Delivery and Treatment of Overactive Bladder

Yongheng Zhou, Qing-Gang Liu, Lin-na Wang, Haoyu Sun, Yixi Liu, Tian-Yu Xiang, Mei-Lin Zhu, Xin Liu, Tao Liu, Huiling Cong, Li-Min Liao

Advanced Healthcare Materials

DOI

2026

ASB2 inhibits lipid accumulation to promote ILC1 homeostatic fitness and anti-tumor immunity in the mouse liver

Boqun Bao, Xianwei Wang, Yawen Chen, Xiaodong Zheng, Yongyan Chen, Haoyu Sun, Guoliang Cui, Rui Sun, Zhigang Tian, Hui Chin Peng

Nature Communications

DOI

2026

The inhibitory receptor CD200R educates ILC1s for optimal cytotoxicity

Yawen Chen, Zhengfeng Zhang, Xianwei Wang, Xiaodong Zheng, Yongyan Chen, Rui Sun, Haoyu Sun, Zhigang Tian, Hui Chin Peng

Proceedings of the National Academy of Sciences

DOI

2026

Histone lactylation-driven intratumoral IGFBP2+ NK cells promote tumor immune evasion

Xuben Wang, Zhuanghao Hou, Qikai Sun, Quanwei Cui, Guirong Shi, Xianghui Du, Ji Liu, Zhigang Nian, Yeben Qian, Guangming Huang, Rongbin Zhou, Zhigang Tian, Haoyu Sun, Haiming Wei, Hongdi Ma, Xiaohu Zheng

Cell Reports

DOI

2026

TIGIT-targeted IL-12 fusion protein engages NK and CD8+ T cells for potent tumor immunotherapy

唐卯星，Yingying Huang，Jiacheng Bi，Dandan Meng，Xiaodong Zheng，Xiaodong Zheng，Hui Peng，Rui Sun，Hongdi Ma，Zhigang Tian，Haoyu Sun，Xiaohu Zheng，Xiaohu Zheng

Cell Reports Medicine

DOI

2026

Cancer stem cells orchestrate immune evasion through extracellular vesicle-mediated non-canonical signaling pathways

Guangjian Fan, Juan Jin, Jie Wang, Jingxuan Xu, Weiyu Ge, Suling Liu, Lei Tang, Wumaier Reziya, Xiaoyi Yang, Junjian Li, Lai Guan Ng, Lijun Di, Yuanting Zheng, Fei Lan, Shizhuo Chen, Yan Zhang, Xin Wang, Dong Gao, Xindong Liu, Haoyu Sun, Yinbing Liu, Ting Li, Yiqun Cao, Zhonghua Tao, Wenting Liu, Hongxia Wang

Cancer Cell

DOI

2025

Intermittent social isolation enhances social investigation but impairs social memory in adult male mice

Shuyan Geng, Zixu Zhang, Xing Liu, Haoyu Sun, Tianxiang Xu, Chuanyao Sun, Shengru Hu, An Liu, Zhiyuan Yang, Wei Xie, Mingdao Mu

Physiology & Behavior，Vol. 291

DOI

2025

Effects of different pulse widths on acute tibial nerve stimulation for overactive bladder in cats

Dong-Sheng Shang, Haoyu Sun, Han Deng, Gongyue Liu, Li-Min Liao, Xing Li

European Journal of Medical Research

DOI

2025

Safety and efficacy of intravesical instillation of botulinum toxin-A in the treatment of interstitial cystitis/bladder pain syndrome and overactive bladder: a systematic review and meta-analysis

Yongheng Zhou, Zitian He, Tian-Yu Xiang, Xiao-Yan Cao, Huiling Cong, Qing-Gang Liu, Haoyu Sun, Limin Liao

Frontiers in Pharmacology

DOI

2025

Investigation into the Acute Effects of Various Waveforms on Tibial Nerve Stimulation for Treating Overactive Bladder in Cats.

Dong-Sheng Shang, Haoyu Sun, Han Deng, Chen Li, Zi-Yu Wang, Linquan Jin, Yun Guo, Xing Li

American Journal of Physiology. Regulatory Integrative and Comparative Physiology

DOI

2025

Effects of pelvic floor electrical stimulation with an implantable device at different frequencies on stress urinary incontinence in rats

Bohong Long, Chen Li, Han Deng, Haoyu Sun, Li-Min Liao, Xing Li

European Journal of Medical Research

DOI

2025

Resting-state functional magnetic resonance imaging reveals the effects of intravesical electrical stimulation on brain activity and functional connectivity in rats with detrusor underactivity.

Han Deng, Li-Min Liao, Xing Li, Yixi Liu, Zitian He, Haoyu Sun

Brain Research Bulletin

DOI

2025

Changes in Brain Activity and Functional Connectivity During Spinal Nerve Stimulation in a Rat Model of Overactive Bladder

Haoyu Sun, Yongheng Zhou, Qing-Gang Liu, Xing Li, Li-Min Liao

International Neurourology Journal

DOI

2025

Research on complications and bladder management of the chronic phase spinal cord injury in China

Haoyu Sun, Han Deng, Yixi Liu, Zitian He, Gongyue Liu, Zhong Chen, Xian-De Huang, Gang Chen, Yan Li, Hai Huang, Jin Tang, L. Pang, Tao Liu, Deyi Luo, Mengyang Zhang, Hui Chen, Li-Min Liao, Xing Li

Scientific Reports

DOI

2025

Implantable electrical stimulation device enhances pelvic floor tissue repair and reduces collagen over-degradation in rats with stress urinary incontinence

Chen Li, Bohong Long, Han Deng, Haoyu Sun, Li-Min Liao, Xing Li

Scientific Reports

DOI

2025

Escitalopram can reverse co-occurring depression and overactive bladder induced by corticosterone in rats.

Gongyue Liu, Zhong-Han Zhou, Xin Liu, Haoyu Sun, Zitian He, Han Deng, Dong-Sheng Shang, Junjie Ji, Li-Min Liao

European Journal of Pharmacology

DOI

2025

αTIGIT-IL2 achieves tumor regression by promoting tumor-infiltrating regulatory T cell fragility in mouse models

Tian-Ci Wang, Yupu Xu, Zhengfeng Zhang, Yaqi Wu, Long Chen, Xiaodong Zheng, Xiaodong Zheng, Hui Peng, Qiang Zou, Rui Sun, Hongdi Ma, Haoyu Sun, Zhigang Tian, Xiaohu Zheng, Xiaohu Zheng

Nature Communications

DOI

2025

Innate lymphoid cells originate from fetal liver–derived tissue-resident progenitors

Xianwei Wang, Jiarui Li, Lucas Rebuffet, Ming Liang Cheng, Boqun Bao, Ya‐Wen Chen, Xiaodong Zheng, Yongyan Chen, Haoyu Sun, Rui Sun, Éric Vivier, Hui Chin Peng, Zhigang Tian

Science Immunology

DOI

2025

CD200R blockade enhances anti-tumor immunity by unleashing NK and CD8+ T cells in tumor

Zhengfeng Zhang, Yu Zhang, Ya–Wen Chen, Guoshuai Cao, Xiaodong Zheng, Rui Sun, Hui Peng, Zhigang Tian, Haoyu Sun

Acta Pharmacologica Sinica

DOI

2025

Cancer stem cells-derived exosomal TSPAN8 enhances non-stem cancer cells stemness and promotes malignant progression in PDAC

Xiaoyi Yang, Rujiao Liu, Juan Jin, Jingxuan Xv, Jiahao Wu, Yijie Jin, Yaya Zhang, Shan Chen, Bin Sun, Moubin Lin, Wumaier Reziya, Junjian Li, Haoyu Sun, Hongxia Wang, Bo Yu, Guangjian Fan, Wenting Liu

Oncogene

DOI

2025

Transcriptome Landscape of Cancer‐Associated Fibroblasts in Human PDAC

Mengyu Tao, Wenting Liu, Jianhua Chen, Rujiao Liu, Jianling Zou, Bo Yu, Chenchen Wang, Mingzhu Huang, Qingjian Chen, Zhe Zhang, Zhiyu Chen, Haoyu Sun, Cheng Zhou, Shuguang Tan, Yuxuan Zheng, Hongxia Wang

Advanced Science

DOI

2024

HHLA2分子研究进展

王远博，孙昊昱

《中国免疫学杂志》

2024

以提升研究生科研素质和能力为目标的专业技术课程教学尝试

孙汭，郑晓东，孙昊昱，田志刚

《中国免疫学杂志》

2024

CD96分子研究进展

周棋杭，孙昊昱

《中国免疫学杂志》

2024

Blockade of CD300A enhances the ability of human NK cells to lyse hematologic malignancies

Shuangcheng Li, Tianci Wang, Xinghui Xiao, Xiaodong Zheng, Haoyu Sun, Rui Sun, Hongdi Ma, Zhigang Tian, Xiaohu Zheng

Cancer Biology & Medicine

2024

A potential therapeutic strategy using a miniature, implantable, wireless nerve stimulation device for treating stress urinary incontinence in rats

Bohong Long, Chen Li, Han Deng, Haoyu Sun, Li-Min Liao, Xing Li

International Urology and Nephrology

DOI

2024

CD49a Targeting Enhances NK Cell Function and Antitumor Immunity

Yu Zhang, Yangyang Li, Z. H. Zhang, Xiaodong Zheng, Hui Chin Peng, Zhigang Tian, Rui Sun, Haoyu Sun

Cancer Immunology Research

DOI

2024

CD94 deficiency or blockade unleashes the anti-tumor immunity in mice and humanized murine models

Jiarui Li, Xianwei Wang, Guoshuai Cao, Yuwei Wu, Ming Cheng, Yawen Chen, Haoyu Sun, Rui Sun, Hui Peng, Zhigang Tian

Cancer Letters

DOI

2024

Author Correction: Targeting myeloid-derived suppressor cells promotes antiparasitic T-cell immunity and enhances the efficacy of PD-1 blockade

Chuanshan Zhang, Hui Wang, Tuerganaili Aji, Liang Li, Yinshi Li, Abidan Ainiwaer, Zibigu Rousu, Jing Li, Maolin Wang, Bingqing Deng, Adilai duolikun, Xuejiao Kang, Xuran Zheng, Qian Yu, Yingmei Shao, Wenbao Zhang, Dominique Angèle Vuitton, Zhigang Tian, Haoyu Sun, Hao Wen

Nature Communications

DOI

2024

Targeting myeloid-derived suppressor cells promotes antiparasitic T-cell immunity and enhances the efficacy of PD-1 blockade

Nature Communications

DOI

2024

The E3 Ubiquitin Ligase FBXO38 Maintains the Antitumor Function of Natural Killer Cells by Sustaining IL15R Signaling

Yongjing Shi, Xiaodong Zheng, Hui Chin Peng, Chenqi Xu, Rui Sun, Zhigang Tian, Haoyu Sun, Xianwei Wang

Cancer Immunology Research

DOI

2023

生命科学本科生免疫生物学课程教学体系构建与探索

孙汭，郑晓东，陈永艳，孙昊昱，魏海明，田志刚

《中国免疫学杂志》

2022

Panoramic comparison between NK cells in healthy and cancerous liver through single-cell RNA sequencing

Huan Liu, Ronghua Zhao, Rongrong Qin, Haoyu Sun, Qiang Huang, Lianxin Liu, Zhigang Tian, Bj?rn Nashan, Cheng Sun, Rui Sun

Cancer Biology & Medicine

2021

培养学生综合能力的“免疫生物学实验课”的探索与尝试

孙汭，郑晓东，陈永艳，孙昊昱，魏海明，田志刚

《中国免疫学杂志》

精选作品

期刊论文

Identify key environmental factors and neglected genetic SNPs associated with obsessive-compulsive disorder by two-sample multivariate Mendelian randomization analysis

Spiky Nanoparticle‐Gel Composite for Efficient Intravesical Botulinum Toxin A Delivery and Treatment of Overactive Bladder

ASB2 inhibits lipid accumulation to promote ILC1 homeostatic fitness and anti-tumor immunity in the mouse liver

The inhibitory receptor CD200R educates ILC1s for optimal cytotoxicity

Histone lactylation-driven intratumoral IGFBP2+ NK cells promote tumor immune evasion

TIGIT-targeted IL-12 fusion protein engages NK and CD8+ T cells for potent tumor immunotherapy

Cancer stem cells orchestrate immune evasion through extracellular vesicle-mediated non-canonical signaling pathways

Intermittent social isolation enhances social investigation but impairs social memory in adult male mice

Effects of different pulse widths on acute tibial nerve stimulation for overactive bladder in cats

Safety and efficacy of intravesical instillation of botulinum toxin-A in the treatment of interstitial cystitis/bladder pain syndrome and overactive bladder: a systematic review and meta-analysis

Investigation into the Acute Effects of Various Waveforms on Tibial Nerve Stimulation for Treating Overactive Bladder in Cats.

Effects of pelvic floor electrical stimulation with an implantable device at different frequencies on stress urinary incontinence in rats

Resting-state functional magnetic resonance imaging reveals the effects of intravesical electrical stimulation on brain activity and functional connectivity in rats with detrusor underactivity.

Changes in Brain Activity and Functional Connectivity During Spinal Nerve Stimulation in a Rat Model of Overactive Bladder

Research on complications and bladder management of the chronic phase spinal cord injury in China

Implantable electrical stimulation device enhances pelvic floor tissue repair and reduces collagen over-degradation in rats with stress urinary incontinence

Escitalopram can reverse co-occurring depression and overactive bladder induced by corticosterone in rats.

αTIGIT-IL2 achieves tumor regression by promoting tumor-infiltrating regulatory T cell fragility in mouse models

Innate lymphoid cells originate from fetal liver–derived tissue-resident progenitors

CD200R blockade enhances anti-tumor immunity by unleashing NK and CD8+ T cells in tumor

Cancer stem cells-derived exosomal TSPAN8 enhances non-stem cancer cells stemness and promotes malignant progression in PDAC

Transcriptome Landscape of Cancer‐Associated Fibroblasts in Human PDAC

HHLA2分子研究进展

以提升研究生科研素质和能力为目标的专业技术课程教学尝试

CD96分子研究进展

Blockade of CD300A enhances the ability of human NK cells to lyse hematologic malignancies

A potential therapeutic strategy using a miniature, implantable, wireless nerve stimulation device for treating stress urinary incontinence in rats

CD49a Targeting Enhances NK Cell Function and Antitumor Immunity

CD94 deficiency or blockade unleashes the anti-tumor immunity in mice and humanized murine models

Author Correction: Targeting myeloid-derived suppressor cells promotes antiparasitic T-cell immunity and enhances the efficacy of PD-1 blockade

Targeting myeloid-derived suppressor cells promotes antiparasitic T-cell immunity and enhances the efficacy of PD-1 blockade

The E3 Ubiquitin Ligase FBXO38 Maintains the Antitumor Function of Natural Killer Cells by Sustaining IL15R Signaling

生命科学本科生免疫生物学课程教学体系构建与探索

Panoramic comparison between NK cells in healthy and cancerous liver through single-cell RNA sequencing

培养学生综合能力的“免疫生物学实验课”的探索与尝试

会议论文

Involvement of TIGIT in NK Cell Exhaustion and Immune Escape in Patients and Mouse Model with Liver E.multilocularis Infection

Blockade of checkpoint receptor PVRIG unleashes anti-tumor immunity of NK cells in murine and human solid tumors

Trispecific killer engager 161519 enhances natural killer cell function and provides anti-tumor activity against CD19-positive cancers

Reduced CD160 expression contributes to impaired NK cell function and poor clinical outcomes in patients with HCC

Reduced CD160 expression contributes to NK cell functional impairment and poor clinical outcomes in patients with HCC

CD200R-induced immune cell exhaustion and immune escape in hepatocellular carcinoma

Regulation of NK cells by hepatoma cell line HepG2.2.15 compared with parental HepG2 demonstrates a possible underlying mechanism of HBV infection

Regulation of human NK cells by hepatocellular carcinoma

The predictive value of Immunoscore in patients with hepatocellular carcinoma

The immune score as a new possible predictive tool and classification for hepatocellular carcinoma