孙志恒｜河南师范大学｜学者主页

2026

Trained Immunity Attenuates Bleomycin-Induced Pulmonary Fibrosis by Promoting AMPK-Mediated Autophagy in Alveolar Macrophages

Xinru Wang, Xinya Guo, Huiwen Meng, Zhiheng Sun

Biology

DOI

2026

Sepsis: Heterogeneity, Immunopathology, and Advances in Therapeutic Strategies

Junxing Qu, Peizhi Li, Zhiheng Sun

The FASEB Journal

DOI

2026

Esketamine attenuated sepsis-induced organ injury in mice via the TGF-β-Smad3 signaling pathway.

Haolan, Yunjie Wang, Yu-Yuan Gao, Yitong Liu, Boxuan Deng, Peizhi Li, Jian-Lin Guo, Zhiheng Sun

Cytokine

DOI

2025

Trained immunity attenuated acute lung injury by activating alveolar macrophages via AKT2-PDK1 axis-mediated metabolic reprogramming

Zhiheng Sun, Huiwen Meng, Xinru Wang, Xinya Guo, Wanyu He, Yanlin Zhou, Ze Wang, Z. Li, Xingbin Li, Yuan Wang

Journal of Translational Medicine

DOI

2024

雌激素在疾病性别差异中的作用及机制研究进展

曲俊星，李培志，孙志恒

《生命科学研究》

2024

Lactate activates ER stress to promote alveolar epithelial cells apoptosis in pulmonary fibrosis

Zhiheng Sun, Wanyu He, Huiwen Meng, Zhihua Ji, Junxing Qu, Guoying Yu

Respiratory Research

DOI

2024

Endoplasmic reticulum stress in acute lung injury and pulmonary fibrosis

Zhiheng Sun, Wanyu He, Huiwen Meng, Peizhi Li, Junxing Qu

The FASEB Journal

DOI

2024

Lactate facilitated mitochondrial fission-derived ROS to promote pulmonary fibrosis via ERK/DRP-1 signaling

Zhiheng Sun, Zhihua Ji, Huiwen Meng, Wanyu He, Bin Li, Xiaoyue Pan, Yanlin Zhou, Guoying Yu

Journal of Translational Medicine

DOI

2024

Lactate accumulation induced by Akt2‐PDK1 signaling promotes pulmonary fibrosis

Zhiheng Sun, Zhihua Ji, Wanyu He, Ruoyu Duan, Junxing Qu, Guoying Yu

The FASEB Journal

DOI

2023

乳酸及单羧酸转运蛋白MCT4在组织纤维化和肿瘤中的作用及应用

余国营，姬志华，温洪智，孙志恒

《河南师范大学学报(自然科学版)》

2022

Correction to: Ferumoxytol Attenuates the Function of MDSCs to Ameliorate LPS-Induced Immunosuppression in Sepsis

Yaxian Xue, Yujun Xu, Xing-Han Liu, Zhiheng Sun, Yuchen Pan, Xia Lu, Hua-Ping Liang, Huan Dou, Y. Hou

Nanoscale Research Letters

DOI

2021

17β-Estradiol promotes LC3B-associated phagocytosis in trained immunity of female mice against sepsis

Zhiheng Sun, Junxing Qu, Xiaoyu Xia, Yuchen Pan, Xing-Han Liu, Hua-Ping Liang, Huan Dou, Ya-Yi Hou

International Journal on Biological Sciences

DOI

2021

C. tropicalis promotes chemotherapy resistance in colon cancer through increasing lactate production to regulate the mismatch repair system

Junxing Qu, Zhiheng Sun, C. Peng, Dao-Qian Li, Wenyue Yan, Zhen Xu, Ya-Yi Hou, S. Shen, Ping Chen, Tingting Wang

International Journal on Biological Sciences

DOI

2020

17β-Estradiol Promotes Trained Immunity in Females Against Sepsis via Regulating Nucleus Translocation of RelB

Zhiheng Sun, Yuchen Pan, Junxing Qu, Yujun Xu, Huan Dou, Ya-Yi Hou

Frontiers in Immunology

DOI

2020

Effects of magnetic fields on immune system, tissue repair and fibrosis

Yi Li, Zhiheng Sun, You-Wei Du, Ya-Yi Hou

DOI

2020

Ganoderma lucidum fruiting body extracts inhibit colorectal cancer by inducing apoptosis, autophagy, and G0/G1 phase cell cycle arrest in vitro and in vivo.

Xing-Han Liu, Yujun Xu, Yi Li, Yuchen Pan, Zhiheng Sun, Shuli Zhao, Ya-Yi Hou

American journal of translational research

2019

Ferumoxytol Attenuates the Function of MDSCs to Ameliorate LPS-Induced Immunosuppression in Sepsis

Yaxian Xue, Yujun Xu, Xing-Han Liu, Zhiheng Sun, Yuchen Pan, Xia Lu, Hua-Ping Liang, Huan Dou, Ya-Yi Hou

Nanoscale Research Letters

DOI

2019

SPIONs enhances IL-10-producing macrophages to relieve sepsis via Cav1-Notch1/HES1-mediated autophagy

Yujun Xu, Yi Li, Xing-Han Liu, Yuchen Pan, Zhiheng Sun, Yaxian Xue, Tingting Wang, Huan Dou, Ya-Yi Hou

International Journal of Nanomedicine

DOI

孙志恒

精选作品

期刊论文

Trained Immunity Attenuates Bleomycin-Induced Pulmonary Fibrosis by Promoting AMPK-Mediated Autophagy in Alveolar Macrophages

Sepsis: Heterogeneity, Immunopathology, and Advances in Therapeutic Strategies

Esketamine attenuated sepsis-induced organ injury in mice via the TGF-β-Smad3 signaling pathway.

Trained immunity attenuated acute lung injury by activating alveolar macrophages via AKT2-PDK1 axis-mediated metabolic reprogramming

雌激素在疾病性别差异中的作用及机制研究进展

Lactate activates ER stress to promote alveolar epithelial cells apoptosis in pulmonary fibrosis

Endoplasmic reticulum stress in acute lung injury and pulmonary fibrosis

Lactate facilitated mitochondrial fission-derived ROS to promote pulmonary fibrosis via ERK/DRP-1 signaling

Lactate accumulation induced by Akt2‐PDK1 signaling promotes pulmonary fibrosis

乳酸及单羧酸转运蛋白MCT4在组织纤维化和肿瘤中的作用及应用

Correction to: Ferumoxytol Attenuates the Function of MDSCs to Ameliorate LPS-Induced Immunosuppression in Sepsis

17β-Estradiol promotes LC3B-associated phagocytosis in trained immunity of female mice against sepsis

C. tropicalis promotes chemotherapy resistance in colon cancer through increasing lactate production to regulate the mismatch repair system

17β-Estradiol Promotes Trained Immunity in Females Against Sepsis via Regulating Nucleus Translocation of RelB

Effects of magnetic fields on immune system, tissue repair and fibrosis

Ganoderma lucidum fruiting body extracts inhibit colorectal cancer by inducing apoptosis, autophagy, and G0/G1 phase cell cycle arrest in vitro and in vivo.

Ferumoxytol Attenuates the Function of MDSCs to Ameliorate LPS-Induced Immunosuppression in Sepsis

SPIONs enhances IL-10-producing macrophages to relieve sepsis via Cav1-Notch1/HES1-mediated autophagy

研究方向