陶余勇｜中国科学技术大学｜学者主页

期刊论文

2026

Cryo‐ EM Structures of the Human 5‐ HT 2B R Bound to Three Distinct Ligands Reveal Molecular Determinants of Subtype Selectivity

Guangyu Yang, Yixuan Zhong, Haizhan Jiao, Yuyong Tao, Qiong Guo

The FASEB Journal

DOI

2025

Structure-guided engineering of snake toxins for selective modulation of adrenergic and muscarinic receptors

Yixuan Zhong, Huihui Tao, Yu Zhang, Binbin He, Haizhan Jiao, Dandan Wang, Maikun Teng, Hongli Hu, Qiong Guo, Yuyong Tao

Nature Communications

DOI

2025

Molecular mechanism of antagonist recognition and regulation of the α1A-adrenoceptor

Sisi Liu, Haizhan Jiao, Yuyong Tao, Dandan Wang, Qiong Guo

Journal of Biological Chemistry

DOI

2025

Inhibition Molecular Mechanism of α 2 Adrenergic Receptor Activation by Antagonist

Yiming Li, Haizhan Jiao, Hongli Hu, Yuyong Tao, Qiong Guo

The FASEB Journal

DOI

2024

Structural insights into physiological activation and antagonism of melanin-concentrating hormone receptor MCHR1

Xiaofang Ye, Guibing Liu, Xiu Li, Binbin He, Yuyong Tao, Jia-Sheng Guan, Yu-Guang Mu, Haiping Liu, Weimin Gong

bioRxiv

DOI

2023

A method for structure determination of GPCRs in various states

Qiong Guo, Binbin He, Yixuan Zhong, Hai-Zhan Jiao, Yinhang Ren, Qinggong Wang, Qiang-Qiang Ge, Yongxiang Gao, Xiangyu Liu, Yang Du, Hong-Li Hu, Yuyong Tao

Nature Chemical Biology

DOI

2023

Structural and dynamic insights into supra-physiological activation and allosteric modulation of a muscarinic acetylcholine receptor

Jun Xu, Qinggong Wang, Harald Hübner, Yunfei Hu, Xiao-Gang Niu, Hao-Qing Wang, S. Maeda, A. Inoue, Yuyong Tao, Peter Gmeiner, Yang Du, Chang-Wen Jin, B. Kobilka

Nature Communications

DOI

2023

Identification and functional validation of FZD8-specific antibodies.

Na Li, Qiangqiang Ge, Qiong Guo, Yuyong Tao

International Journal of Biological Macromolecules

DOI

2023

Engineering a modular double-transmembrane synthetic receptor system for customizing cellular programs

Jingru Zhou, Qiangqiang Ge, Dandan Wang, Qiong Guo, Yuyong Tao

Cell Reports

DOI

2022

An epitope-directed selection strategy facilitating the identification of Frizzled receptor selective antibodies.

Qiang-Qiang Ge, M. Teng, Xu Li, Qiong Guo, Yuyong Tao

Structure

DOI

2022

Structural basis of the ligand binding and signaling mechanism of melatonin receptors

Qinggong Wang, Qiuyuan Lu, Qiong Guo, M. Teng, Q. Gong, Xu Li, Yang Du, Zheng Liu, Yuyong Tao

Nature Communications

DOI

2022

A potent synthetic nanobody with broad-spectrum activity neutralizes SARS-CoV-2 virus and the Omicron variant BA.1 through a unique binding mode

Dongping Zhao, Liqin Liu, Xin-Lin Liu, Jin-Lei Zhang, Yuqing Yin, Linli Luan, Dingwen Jiang, Xiong Yang, Lei Li, Hua-long Xiong, Dongming Xing, Q. Zheng, N. Xia, Yuyong Tao, Shaowei Li, Hai-Ming Huang

Journal of Nanobiotechnology

DOI

2021

A Genetically Encoded Bioluminescent System for Fast and Highly Sensitive Detection of Antibodies with a Bright Green Fluorescent Protein.

Mengying Deng, Jing Yuan, Haibin Yang, Xuli Wu, Xiaoyuan Wei, Yang Du, Garry Wong, Yuyong Tao, Gang Liu, Zong-Wen Jin, Jun Chu

ACS Nano

DOI

2020

Interface switch mediates signal transmission in a two-component system

Mingxing Wang, Qiong Guo, Kongfu Zhu, Bo Fang, Yi-Fan Yang, M. Teng, Xu Li, Yuyong Tao

Proceedings of the National Academy of Sciences of the United States of America

DOI

2019

Tailored tetravalent antibodies potently and specifically activate Wnt/Frizzled pathways in cells, organoids and mice

Yuyong Tao, Monika Miś, Levi L. Blazer, M. Ustav, Z. Steinhart, Rony Chidiac, Elli Kubarakos, Siobhan O'Brien, Xiaomei Wang, N. Jarvik, N. Patel, Jarrett J. Adams, J. Moffat, S. Angers, S. Sidhu

eLife

DOI

2019

Author response: Tailored tetravalent antibodies potently and specifically activate Wnt/Frizzled pathways in cells, organoids and mice

Yuyong Tao, Monika Miś, Levi L. Blazer, M. Ustav, Z. Steinhart, Rony Chidiac, Elli Kubarakos, Siobhan O'Brien, Xiaomei Wang, N. Jarvik, N. Patel, Jarrett J. Adams, J. Moffat, S. Angers, S. Sidhu

DOI

2015

Structure of a eukaryotic SWEET transporter in a homo-trimeric complex

Yuyong Tao, Lily S. Cheung, Shuo Li, J. Eom, Li-Qing Chen, Yan Xu, K. Perry, W. Frommer, Liang Feng

Nature

DOI

2014

Structures of SemiSWEET transporters in two distinct conformations

Yan Xu, Yuyong Tao, Lily S. Cheung, C. Fan, Li-Qing Chen, Sophia Y. Xu, K. Perry, W. Frommer, Liang Feng

Nature

DOI

2013

Structural insights into the role of the Chl4-Iml3 complex in kinetochore assembly.

Qiong Guo, Yuyong Tao, Hejun Liu, M. Teng, Xu Li

Acta Crystallographica Section D: Biological Crystallography

DOI

2012

The structure of the FANCM-MHF complex reveals physical features for functional assembly

Yuyong Tao, Chang-Jiang Jin, Xu Li, Shali Qi, Ling-Luo Chu, L. Niu, Xue-Biao Yao, M. Teng

Nature Communications

DOI

2012

Structural Analysis of Shu Proteins Reveals a DNA Binding Role Essential for Resisting Damage*

Yuyong Tao, Xu Li, Yiwei Liu, J. Ruan, Shali Qi, L. Niu, M. Teng

Journal of Biological Chemistry

DOI

2012

Structural insights into decreased enzymatic activity induced by an insert sequence in mannonate dehydratase from Gram negative bacterium.

X. Qiu, Yuyong Tao, Yuwei Zhu, Ye Yuan, Yujie Zhang, Hejun Liu, Yongxiang Gao, M. Teng, L. Niu

Journal of Structural Biology

DOI

会议论文

2010

Crystal structure and function studies of yeast vesicular transport related proteins

Pengfei Fang, Jing Wang, Yuyong Tao

《中国生物化学与分子生物学会第十届会员代表大会暨全国学术会议摘要集》

陶余勇

精选作品

期刊论文

Cryo‐ EM Structures of the Human 5‐ HT 2B R Bound to Three Distinct Ligands Reveal Molecular Determinants of Subtype Selectivity

Structure-guided engineering of snake toxins for selective modulation of adrenergic and muscarinic receptors

Molecular mechanism of antagonist recognition and regulation of the α1A-adrenoceptor

Inhibition Molecular Mechanism of α 2 Adrenergic Receptor Activation by Antagonist

Structural insights into physiological activation and antagonism of melanin-concentrating hormone receptor MCHR1

A method for structure determination of GPCRs in various states

Structural and dynamic insights into supra-physiological activation and allosteric modulation of a muscarinic acetylcholine receptor

Identification and functional validation of FZD8-specific antibodies.

Engineering a modular double-transmembrane synthetic receptor system for customizing cellular programs

An epitope-directed selection strategy facilitating the identification of Frizzled receptor selective antibodies.

Structural basis of the ligand binding and signaling mechanism of melatonin receptors

A potent synthetic nanobody with broad-spectrum activity neutralizes SARS-CoV-2 virus and the Omicron variant BA.1 through a unique binding mode

A Genetically Encoded Bioluminescent System for Fast and Highly Sensitive Detection of Antibodies with a Bright Green Fluorescent Protein.

Interface switch mediates signal transmission in a two-component system

Tailored tetravalent antibodies potently and specifically activate Wnt/Frizzled pathways in cells, organoids and mice

Author response: Tailored tetravalent antibodies potently and specifically activate Wnt/Frizzled pathways in cells, organoids and mice

Structure of a eukaryotic SWEET transporter in a homo-trimeric complex

Structures of SemiSWEET transporters in two distinct conformations

Structural insights into the role of the Chl4-Iml3 complex in kinetochore assembly.

The structure of the FANCM-MHF complex reveals physical features for functional assembly

Structural Analysis of Shu Proteins Reveals a DNA Binding Role Essential for Resisting Damage*

Structural insights into decreased enzymatic activity induced by an insert sequence in mannonate dehydratase from Gram negative bacterium.

会议论文

Crystal structure and function studies of yeast vesicular transport related proteins

研究方向