百晓学者学者目录

李川川

助理教授、博士生导师、教授，复旦大学

精选作品

期刊论文

2026

KRAS靶向药研究进展

李明聪，周岳嵩，乔泰，白卿霖，李川川

《中国科学:生命科学》

2026

Butyrate Enhances Anti-PD-1 Antitumor Efficacy in Lung Cancer via Modulating STAT1/IDO1-Mediated Tryptophan-Kynurenine Pathway

Chuanchuan Li, Xi-Xi Li, Bo Ma, F. Yuan, Shou-Zhong Wang, Weixian Liu

Discover medicine

DOI

2025

Human annexin A5 promotes glioma progression by targeting the MAPK/CD44 pathway

Wei-xian Liu, Tao Xiong, Hu Sun, Ming Wang, Jungao Zhu, Chuanchuan Li

Frontiers in Oncology

DOI

2023

Chemical remodeling of a cellular chaperone to target the active state of mutant KRAS

C. Schulze, Kyle J. Seamon, Yu-Lei Zhao, Y. C. Yang, J. Cregg, Dongsung Kim, A. Tomlinson, T. Choy, Zhican Wang, Ben Sang, Y. Pourfarjam, J. Lucas, Antonio Cuevas-Navarro, Carlos Ayala-Santos, Alberto Vides, Chuanchuan Li, A. Marquez, Mengqi Zhong, Vidyasiri Vemulapalli, C. Weller, Andrea Gould, D. Whalen, Anthony Salvador, Anthony N. Milin, Mae Saldajeno-Concar, Nuntana Dinglasan, Anqi Chen, James W. Evans, J. Knox, E. Koltun, Mallika Singh, R. Nichols, D. Wildes, A. Gill, Jacqueline A. M. Smith, P. Lito

Science

DOI

2023

Pan-KRAS inhibitor disables oncogenic signalling and tumour growth

Dongsung Kim, Lorenz Herdeis, D. Rudolph, Yu-Lei Zhao, Jark Böttcher, Alberto Vides, Carlos Ayala-Santos, Y. Pourfarjam, Antonio Cuevas-Navarro, Jenny Y. Xue, A. Mantoulidis, Joachim Bröker, Tobias Wunberg, Otmar Schaaf, Johannes Popow, B. Wolkerstorfer, K. Kropatsch, Rui-Rui Qu, E. de Stanchina, Ben Sang, Chuanchuan Li, D. McConnell, N. Kraut, P. Lito

Nature

DOI

2022

MiRNA-144-5p down-modulates CDCA3 to regulate proliferation and apoptosis of lung adenocarcinoma cells.

Jing Luo, Lilong Xia, Lei Zhang, Kaixiang Zhao, Chuanchuan Li

Mutation research

DOI

2021

Diverse alterations associated with resistance to KRAS(G12C) inhibition

Yu-Lei Zhao, Y. Murciano-Goroff, Jenny Y. Xue, A. Ang, J. Lucas, T. Mai, Arnaud Da Cruz Paula, Anne Y. Saiki, Deanna Mohn, P. Achanta, Anne Sisk, K. Arora, R. S. Roy, Dongsung Kim, Chuanchuan Li, L. Lim, Mark Li, Amber Bahr, Brian Loomis, E. de Stanchina, J. Reis-Filho, B. Weigelt, M. Berger, Gregory Riely, K. Arbour, J. Lipford, Bob T. Li, P. Lito

Nature

DOI

2021

The G-protein signaling regulator RGS3 enhances the GTPase activity of KRAS

Chuanchuan Li, Alberto Vides, Dongsung Kim, Jenny Y. Xue, Yu-Lei Zhao, P. Lito

Science

DOI

2020

Rapid non-uniform adaptation to conformation-specific KRASG12C inhibition

Jenny Y. Xue, Yu-Lei Zhao, J. Aronowitz, T. Mai, Alberto Vides, Besnik Qeriqi, Dongsung Kim, Chuanchuan Li, E. de Stanchina, L. Mazutis, D. Risso, P. Lito

Nature

DOI

2020

Abstract 622: Rapid non-uniform adaptation to conformation-specific KRAS G12Cinhibition

Jenny Y. Xue, Yu-Lei Zhao, J. Aronowitz, T. Mai, Alberto Vides, Besnik Qeriqi, Dongsung Kim, Chuanchuan Li, E. de Stanchina, L. Mazutis, D. Risso, P. Lito

Experimental and Molecular Therapeutics

DOI

2019

Abstract LB-A04: Rapid non-uniform adaptation to conformation-specific KRAS G12C inhibition

Jenny Y. Xue, Yu-Lei Zhao, J. Aronowitz, T. Mai, Alberto Vides, Besnik Qeriqi, Dongsung Kim, Chuanchuan Li, E. de Stanchina, L. Mazutis, D. Risso, P. Lito

Cellular Responses to Therapy

DOI

2017

microRNA-664 enhances proliferation, migration and invasion of lung cancer cells.

Xinhai Zhu, Sheng Ju, F. Yuan, Guo-Ping Chen, Yue Shu, Chuanchuan Li, Yanhui Xu, Jing Luo, Lilong Xia

Experimental and Therapeutic Medicine

DOI

研究方向

肿瘤靶向药和临床转化

此主页由公开资料整理，尚未经学者本人认领。