侯永强｜厦门大学｜学者主页

2026

Small interfering RNA-mediated silencing of mutant NPM1 suppresses acute myeloid leukemia via reversing KAT7 and p300-mediated histone acetylation

Yongqiang Hou, Yunzhi Xing, Chun-Jie Chen, Dongxue Su, Zhi'en Zhou, Yi Ye, Zhangjian Lai, Zhixian Peng, Hongxia Cai, Min Sun, Yue Liu, Bingying Yang, Hai-Tao Huang, Zhe Li, Jin-Huan Li, Jun-Hong Li, Huan Gao, Jia-Xi Li, Hao Zhao, Yi-Ran Shi, Qing-Hua Chen, Jun Long, Jiong Hu, Dawang Zhou, Lan-Fen Chen

Leukemia

DOI

2025

Pharmacological targeting of large tumor suppressor kinases (LATS) 1 and 2 augments tissue repair and regeneration

Chen Xiao, Zhenhua Wu, Liuqi Liao, Chao Shi, Huan Gao, Ting Zhang, Qing-Hua Chen, Yongqiang Hou, Cai-Hong Yun, Dongxue Su, Dawang Zhou, Xian-Ming Deng, Lan-Fen Chen

British Journal of Pharmacology

DOI

2024

Osr2 functions as a biomechanical checkpoint to aggravate CD8+ T cell exhaustion in tumor.

Jinjia Zhang, Jun-Hong Li, Yongqiang Hou, Yao Lin, Hao Zhao, Yi-Ran Shi, Kai-Yun Chen, Nian Cheng, Jiayu Tang, Lei Pan, Yunzhi Xing, Huan Gao, Bingying Yang, Zeng-Fang Song, Yao Cheng, Yue Liu, Min Sun, Yue-Yue Linghu, Jia-Xi Li, Hai-Tao Huang, Zhangjian Lai, Zhi'en Zhou, Zi-Feng Li, Xiu-Feng Sun, Qing-Hua Chen, Dongxue Su, WenGang Li, Zhi-Hai Peng, Pingguo Liu, Wei Chen, Hong-Ling Huang, Yi-Xin Chen, Bailong Xiao, Li-Lin Ye, Lan-Fen Chen, Da-Wang Zhou

Cell

DOI

2023

SPTAN1/NUMB axis senses cell density to restrain cell growth and oncogenesis through Hippo signaling

Dongxue Su, Yuxi Li, Weiji Zhang, Huan Gao, Yao Cheng, Yongqiang Hou, Jun-Hong Li, Yi Ye, Zhangjian Lai, Zhe Li, Hai-Tao Huang, Jia-Xi Li, Jin-Huan Li, Meng-Yu Cheng, Nian Cheng, N. Wu, Zhi'en Zhou, Yunzhi Xing, Yu Zhao, He-He Liu, Jiayu Tang, Qing-Hua Chen, Li-Xin Hong, WenGang Li, Zhi-Hai Peng, Bin Zhao, Randy L. Johnson, Pingguo Liu, Wan-Jin Hong, Lanfen Chen, Da-Wang Zhou

Journal of Clinical Investigation

DOI

2021

Bimodal regulation of the PRC2 complex by USP7 underlies tumorigenesis

Dongxue Su, Wenjuan Wang, Yongqiang Hou, Liyong Wang, Xianfu Yi, Cheng Cao, Yue-Jia Wang, Huan Gao, Yue Wang, Chao-Xu Yang, Bei-bei Liu, Xing Chen, Xiaodi Wu, Jiajing Wu, Dong Yan, Shuqi Wei, Lulu Han, Shu-Meng Liu, Qian Wang, Lei Shi, Shan Lin

Nucleic Acids Research

DOI

2019

MicroRNA-455-3p mediates GATA3 tumor suppression in mammary epithelial cells by inhibiting TGF-β signaling

Yi Zeng, Tianyan Gao, Wei Huang, Yang Yang, R. Qiu, Yongqiang Hou, Wen-Qiang Yu, S. Leng, Da-qin Feng, Wei Liu, Xu Teng, Hefen Yu, Yan Wang

Journal of Biological Chemistry

DOI

2019

Regulation of EZH2 by SMYD2-Mediated Lysine Methylation Is Implicated in Tumorigenesis.

Yi Zeng, R. Qiu, Yang Yang, Tianyan Gao, Yu Zheng, Wei Huang, Jie Gao, Kaiming Zhang, Ruiqiong Liu, Shuang Wang, Yongqiang Hou, Wen-Qiang Yu, S. Leng, Da-qin Feng, Wei Liu, Xi Zhang, Yan Wang

Cell Reports

DOI

2019

GATA3 recruits UTX for gene transcriptional activation to suppress metastasis of breast cancer

Wen-Qiang Yu, Wei Huang, Yang Yang, R. Qiu, Yi Zeng, Yongqiang Hou, Gancheng Sun, Hang Shi, S. Leng, Da-qin Feng, Yang Chen, Shuang Wang, Xu Teng, Hefen Yu, Yan Wang

Cell Death and Disease

DOI

2018

LSD1 coordinates with the SIN3A/HDAC complex and maintains sensitivity to chemotherapy in breast cancer

Yang Yang, Wei Huang, R. Qiu, Ruiqiong Liu, Yi Zeng, Jie Gao, Yu Zheng, Yongqiang Hou, Shuang Wang, Wen-Qiang Yu, S. Leng, Da-qin Feng, Yan Wang

Journal of Molecular Cell Biology

DOI

2018

BRMS1 coordinates with LSD1 and suppresses breast cancer cell metastasis.

R. Qiu, Hang Shi, Shuang Wang, S. Leng, Ruiqiong Liu, Yu Zheng, Wei Huang, Yi Zeng, Jie Gao, Kaiming Zhang, Yongqiang Hou, Da-qin Feng, Yang Yang

American Journal of Cancer Research

2018

The Homeotic Protein SIX3 Suppresses Carcinogenesis and Metastasis through Recruiting the LSD1/NuRD(MTA3) Complex

Yu Zheng, Yi Zeng, R. Qiu, Ruiqiong Liu, Wei Huang, Yongqiang Hou, Shuang Wang, S. Leng, Da-qin Feng, Yang Yang, Yan Wang

Theranostics

DOI

2018

PHD finger protein 1 (PHF1) is a novel reader for histone H4R3 symmetric dimethylation and coordinates with PRMT5–WDR77/CRL4B complex to promote tumorigenesis

Ruiqiong Liu, Jie Gao, Yang Yang, R. Qiu, Yu Zheng, Wei Huang, Yi Zeng, Yongqiang Hou, Shuang Wang, S. Leng, Da-qin Feng, Wen-Qiang Yu, Gancheng Sun, Hang Shi, Xu Teng, Yan Wang

Nucleic Acids Research

DOI

2016

FOXK2 Elicits Massive Transcription Repression and Suppresses the Hypoxic Response and Breast Cancer Carcinogenesis.

Shan Lin, Xing Zhou, Xin-Hua Liu, Yue Wang, Dongxue Su, Yongqiang Hou, Na Yu, Chao-Xu Yang, Bei-bei Liu, Jie Gao, Y. Duan, Jianguo Yang, Wanjin Li, Jing Liang, Luyang Sun, Ke-Xin Chen, Cheng-Hao Xuan, Lei Shi, Yan Wang, Y. Shang

Cancer Cell

DOI

侯永强

精选作品

期刊论文

Small interfering RNA-mediated silencing of mutant NPM1 suppresses acute myeloid leukemia via reversing KAT7 and p300-mediated histone acetylation

Pharmacological targeting of large tumor suppressor kinases (LATS) 1 and 2 augments tissue repair and regeneration

Osr2 functions as a biomechanical checkpoint to aggravate CD8+ T cell exhaustion in tumor.

SPTAN1/NUMB axis senses cell density to restrain cell growth and oncogenesis through Hippo signaling

Bimodal regulation of the PRC2 complex by USP7 underlies tumorigenesis

MicroRNA-455-3p mediates GATA3 tumor suppression in mammary epithelial cells by inhibiting TGF-β signaling

Regulation of EZH2 by SMYD2-Mediated Lysine Methylation Is Implicated in Tumorigenesis.

GATA3 recruits UTX for gene transcriptional activation to suppress metastasis of breast cancer

LSD1 coordinates with the SIN3A/HDAC complex and maintains sensitivity to chemotherapy in breast cancer

BRMS1 coordinates with LSD1 and suppresses breast cancer cell metastasis.

The Homeotic Protein SIX3 Suppresses Carcinogenesis and Metastasis through Recruiting the LSD1/NuRD(MTA3) Complex

PHD finger protein 1 (PHF1) is a novel reader for histone H4R3 symmetric dimethylation and coordinates with PRMT5–WDR77/CRL4B complex to promote tumorigenesis

FOXK2 Elicits Massive Transcription Repression and Suppresses the Hypoxic Response and Breast Cancer Carcinogenesis.

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