许琳｜青岛大学｜学者主页

2025

piR-16404 drives ferroptotic liver injury via CASTOR1/mTORC1/GPX4 dysregulation in HepG2 cells and mice: a novel toxicity mechanism of N, N-dimethylformamide

Wanli Ma, Xiaoyu Huo, Ruoxi Li, Jingjing Xing, Lin Xu, Dianke Yu

Archives of Toxicology

2023

An entropy weight method to integrate big omics and mechanistically evaluate DILI

Yuan Jin, Yingqing Shou, Qinkai Lei, Chenlong Du, Lin Xu, Ningning Chen, Wanli Ma, Xiaoxiao Zhu, Shuya Zhou, Yuxin Zheng, Dianke Yu

Hepatology

DOI

2023

Diesel exhaust particles exposure induces liver dysfunction: Exploring predictive potential of human circulating microRNAs signature relevant to liver injury risk

Lin Xu, Yanting Li, Wanli Ma, Xueying Sun, Rongrong Fan, Yuan Jin, Ningning Chen, Xiaoxiao Zhu, Huan Guo, Kunming Zhao, Jiao Luo, Chuanhai Li, Yuxin Zheng, Dianke Yu

Journal of Hazardous Materials

DOI

2022

N, N-dimethylformamide exposure induced liver abnormal mitophagy by targeting miR-92a-1-5p-BNIP3L pathway in vivo and vitro

Lin Xu, Wanli Ma, Yuan Jin, Xueying Sun, Ningning Chen, Xiaoxiao Zhu, Jiao Luo, Chuanhai Li, Kunming Zhao, Yuxin Zheng, Dianke Yu

The Science of The Total Environment

DOI

2021

二甲基甲酰胺致肝损伤的关键毒性通路及表观遗传学分子机制研究

许琳

《青岛大学》

2021

PIWI-interacting RNA-23210 protects against acetaminophen-induced liver injury by targeting HNF1A and HNF4A

Lin Xu, Wendi Chen, Jing Chen, Yuan Jin, Wanli Ma, Guangshuai Qi, Xueying Sun, Jiao Luo, Chuanhai Li, Kunming Zhao, Yuxin Zheng, Dianke Yu

Biochemical Pharmacology

DOI

2021

A novel epigenetic mechanism unravels hsa-miR-148a-3p-mediated CYP2B6 downregulation in alcoholic hepatitis disease

Jiao Luo, Mengyue Xie, Yufei Hou, Wanli Ma, Yuan Jin, Jing Chen, Chuanhai Li, Kunming Zhao, Ningning Chen, Lin Xu, Yanan Ji, Qianqian Zhang, Yuxin Zheng, Dianke Yu

Biochemical Pharmacology

DOI

2021

A novel mechanism underlying alcohol dehydrogenase expression: hsa-miR-148a-3p promotes ADH4 expression via an AGO1-dependent manner in control and ethanol-exposed hepatic cells

Jiao Luo, Yufei Hou, Wanli Ma, Mengyue Xie, Yuan Jin, Lin Xu, Chuanhai Li, Ying Wang, Jing Chen, Wendi Chen, Yuxin Zheng, Dianke Yu

Biochemical Pharmacology

DOI

2021

miR-15a-3p Protects Against Isoniazid-Induced Liver Injury via Suppressing N-Acetyltransferase 2 Expression

Xinmei Li, Heng Zhang, Lin Xu, Yuan Jin, Jiao Luo, Chuanhai Li, Kunming Zhao, Yuxin Zheng, Dianke Yu, Yanjie Zhao

Frontiers in Molecular Biosciences

DOI

2020

Integration of proteomics, lipidomics, and metabolomics reveals novel metabolic mechanisms underlying N, N-dimethylformamide induced hepatotoxicity

Lin Xu, Qianwen Zhao, Jiao Luo, Wanli Ma, Yuan Jin, Chuanhai Li, Yufei Hou, Meiyao Feng, Ying Wang, Jing Chen, Jinquan Zhao, Yuxin Zheng, Dianke Yu

Ecotoxicology and Environmental Safety

DOI

2020

Coordinated Regulation of UGT2B15 Expression by Long Noncoding RNA LINC00574 and hsa-miR-129-5p in HepaRG Cells

Dianke Yu, Jing Chen, Si Chen, Lin Xu, Leihong Wu, Dongying Li, Jiao Luo, Yuan Jin, Yanjie Zhao, Bridgett Knox, William H. Tolleson, Xubing Wang, Lei Guo, Weida Tong, Baitang Ning

Drug Metabolism and Disposition

DOI

2015

CYP3A5 Functions as a Tumor Suppressor in Hepatocellular Carcinoma by Regulating mTORC2/Akt Signaling.

F. Jiang, Lei Chen, Ying-Chen Yang, Xian-Ming Wang, Ruo-Yu Wang, Liang Li, W. Wen, Yan-Ling Chang, Cai-Yang Chen, Jing Tang, Gaomiyang Liu, Wen-Tao Huang, Lin Xu, Hong-Yang Wang

Cancer Research

DOI

许琳

精选作品

期刊论文

piR-16404 drives ferroptotic liver injury via CASTOR1/mTORC1/GPX4 dysregulation in HepG2 cells and mice: a novel toxicity mechanism of N, N-dimethylformamide

An entropy weight method to integrate big omics and mechanistically evaluate DILI

Diesel exhaust particles exposure induces liver dysfunction: Exploring predictive potential of human circulating microRNAs signature relevant to liver injury risk

N, N-dimethylformamide exposure induced liver abnormal mitophagy by targeting miR-92a-1-5p-BNIP3L pathway in vivo and vitro

二甲基甲酰胺致肝损伤的关键毒性通路及表观遗传学分子机制研究

PIWI-interacting RNA-23210 protects against acetaminophen-induced liver injury by targeting HNF1A and HNF4A

A novel epigenetic mechanism unravels hsa-miR-148a-3p-mediated CYP2B6 downregulation in alcoholic hepatitis disease

A novel mechanism underlying alcohol dehydrogenase expression: hsa-miR-148a-3p promotes ADH4 expression via an AGO1-dependent manner in control and ethanol-exposed hepatic cells

miR-15a-3p Protects Against Isoniazid-Induced Liver Injury via Suppressing N-Acetyltransferase 2 Expression

Integration of proteomics, lipidomics, and metabolomics reveals novel metabolic mechanisms underlying N, N-dimethylformamide induced hepatotoxicity

Coordinated Regulation of UGT2B15 Expression by Long Noncoding RNA LINC00574 and hsa-miR-129-5p in HepaRG Cells

CYP3A5 Functions as a Tumor Suppressor in Hepatocellular Carcinoma by Regulating mTORC2/Akt Signaling.

研究方向