百晓学者学者目录

唐卓

博士生导师、教授、研究员，西华大学

精选作品

期刊论文

2026

RNA-based ATTEC: an RNA-guided autophagy-lysosome platform for targeted protein degradation.

Yunqiu Zhang, Wanting Yang, Yan Xu, Ding-Qiang Fu, Xiao-Kang Nie, Feng Du, Juan Dong, Fei Wang, Xin Cui, Zhuo Tang

Bioorganic & Medicinal Chemistry

DOI

2026

ICR-LAMP: A one-pot isothermal assay enabled by transient spatial separation and dynamic ICR for high-specificity SNP genotyping.

Juan Dong, Jin-Yi Shi, Jun Zhao, Xin Chen, Guo-Qiang Zhan, Feng Du, Xin Cui, Wei Wang, Sheng Ding, Zhuo Tang

Biosensors & bioelectronics

DOI

2026

Universal contamination-free nucleic acid biosensing enabled by guide-independent Argonaute amplicon elimination.

Jin-Yi Shi, Sheng Ding, Feng Du, Juan Dong, Si-Fan Wang, Kai-Yuan Ren, Jing Li, Hai-Yang Li, Cheng-Ze Wu, Song Zhao, Xi-Jun Yang, Fei Wang, Wei Wang, Rong Chen, Xin Cui, Zhuo Tang

Biosensors & bioelectronics

DOI

2026

tRNA-Fused Strategy for Enhancing RNA Aptamer Sensor Stability

Jiawei Zou, Juan Dong, Zhuo Tang, Wei Wang, Feng Du

Chemosensors

DOI

2025

Ultrasensitive RNase H activity detection using the transcription-based hybrid probe and CRISPR/cas12a signal amplifier

Sheng Ding, Yinghua Wei, Minglong Yang, Jin-Yi Shi, Kai-Yuan Ren, Xinli Li, Zhuo Tang

Frontiers in Pharmacology

DOI

2025

One-Pot Detection of Biomarker Apurinic/Apyrimidinic Endonuclease 1 Based on the Modified-crRNA Regulated Trans-Cleavage Activity of CRISPR/Cas12a.

Sheng Ding, Hai-Yang Li, Jing Li, Dianxiang Lu, Jin Yang, Zhuo Tang

ACS Synthetic Biology

DOI

2025

Detection of lead contamination using DNAzyme and split activator-triggered CRISPR/Cas12a.

Kai-Yuan Ren, Sheng Ding, Jin-Yi Shi, Juan Dong, Feng Du, Zhuo Tang

Talanta: The International Journal of Pure and Applied Analytical Chemistry

DOI

2025

Enhancing RNA editing efficiency and specificity with engineered ADAR2 guide RNAs

Xilei Ai, Sheng Ding, Shana Zhou, Feng Du, Shuai Liu, Xin Cui, Juan Dong, Xin Huang, Zhuo Tang

Molecular Therapy: Nucleic Acids

DOI

2025

Integrating commercial personal glucose meter with peroxidase-mimic DNAzyme to develop a versatile point-of-care biosensing platform.

Sheng Ding, Juan Dong, Jin-Yi Shi, Kai-Yuan Ren, Xin Cui, Zheng Shi, Na Li, Yijia Xiang, Feng Du, Zhuo Tang

Biosensors & bioelectronics

DOI

2025

Aptazyme-directed A-to-I RNA editing.

Xilei Ai, Zhuo Tang

Methods in Enzymology

DOI

2024

Leveraging CRISPR/Cas12 signal amplifier to sensitive detection of apurinic/apyrimidinic endonuclease 1 and high-throughput inhibitor screening.

Sheng Ding, Yi Yuan, Juan Dong, Feng Du, Xin Cui, Zheng Shi, Zhuo Tang

Analytica Chimica Acta

DOI

2024

Ultrafast DNA detection based on turn-back loop primer-accelerated LAMP (TLAMP).

Jin-Yi Shi, Sheng Ding, Chen Li, Gang-Yi Chen, Feng Du, Si-Fan Wang, Ai-Qin Yue, Kai-Yuan Ren, Zhi-rong Yang, Pei Xu, Juan Dong, Jin-Zhong Zhao, Zhuo Tang

Analytica Chimica Acta

DOI

2024

Antitumor Effect of Anti‐c‐Myc Aptamer‐Based PROTAC for Degradation of the c‐Myc Protein

Yuchun Wang, Gang Yang, Xin-Yu Zhang, Ruoling Bai, Deyu Yuan, Denghui Gao, Qianyu He, Yi Yuan, Xing-He Zhang, Jun-Chuang Kou, Li-hua Zheng, Yanxin Huang, Zhuo Tang, Yong-Li Bao, Xu Song, Yong-Yun Zhao

Advancement of science

DOI

2023

Live-Cell Imaging of Endogenous RNA with a Genetically Encoded Fluorogenic Allosteric Aptamer.

Yan Peng, Linjuan Shu, Xiong-Fei Deng, Xin Huang, Xian-Ming Mo, Feng Du, Zhuo Tang

Analytical Chemistry

DOI

2023

The aptamer-based RNA-PROTAC.

Yan Xu, Yi Yuan, Ding-Qiang Fu, Yi Fu, Shanggen Zhou, Wan-Ting Yang, Xu-Yang Wang, Guang-Xun Li, Juan Dong, Feng Du, Xin Huang, Qiwei Wang, Zhuo Tang

Bioorganic & Medicinal Chemistry

DOI

2023

Trans-acting aptazyme for conditional gene knockdown in eukaryotic cells

Shana Zhou, Meiyi Chen, Yi Yuan, Yan Xu, Qinlin Pu, Xilei Ai, Shuai Liu, Feng Du, Xin Huang, Juan Dong, Xin Cui, Zhuo Tang

Molecular Therapy: Nucleic Acids

DOI

2023

Leveraging Small Molecule-Induced Aptazyme Cleavage for Directed A-to-I RNA Editing.

Xilei Ai, Shana Zhou, Meiyi Chen, Feng Du, Yi Yuan, Xin Cui, Juan Dong, Xin Huang, Zhuo Tang

ACS Synthetic Biology

DOI

2022

A heterobifunctional molecule recruits cereblon to an RNA scaffold and activates its PROTAC function

Yan Xu, Ding-Qiang Fu, Yi Yuan, Yan Peng, Juan Dong, Feng Du, Xin Huang, Guang-Xun Li, Xiaohua Chen, Qiwei Wang, Zhuo Tang

Cell Reports Physical Science

DOI

2022

Detection of Cancer Marker Flap Endonuclease 1 Using One-Pot Transcription-Powered Clustered Regularly Interspaced Short Palindromic Repeat/Cas12a Signal Expansion.

Sheng Ding, Yinghua Wei, Gang-Yi Chen, Feng Du, Xin Cui, Xin Huang, Yi Yuan, Juan Dong, Zhuo Tang

Analytical Chemistry

DOI

2022

All-in-one multiplex isothermal reaction combining miniaturized device enables rapid screening of infected samples

Sheng Ding, Yinghua Wei, Juan Dong, Feng Du, Xin Cui, Zhuo Tang

Sensors and Actuators B: Chemical

DOI

2022

Real-time fluorescence and colorimetric identification of bulbus fritillariae using recombinase assisted loop-mediated isothermal DNA amplification (RALA)

Yinghua Wei, Sheng Ding, Gang-Yi Chen, Juan Dong, Feng Du, Xin Huang, Xin Cui, Rong Chen, Zhuo Tang

Frontiers in Plant Science

DOI

2022

Pt(IV) Prodrug as a Potential Antitumor Agent with APE1 Inhibitory Activity.

Yi Yuan, Ding-Qiang Fu, Yan Xu, Xu-Yang Wang, Xiong-Fei Deng, Shan Zhou, Feng Du, Xin Cui, Yun Deng, Zhuo Tang

Journal of Medicinal Chemistry

DOI

2022

Organelle-targeted imaging based on fluorogen-activating RNA aptamers in living cells.

Yan Peng, Xilei Ai, Yi Yuan, Juan Dong, Xin Cui, Feng Du, Xin Huang, Zhuo Tang

Analytica Chimica Acta

DOI

2021

Combining protein and RNA quantification to evaluate promoter activity by using dual-color fluorescent reporting systems

Yan Peng, Xin Huang, Tian-Fang Huang, Feng Du, Xin Cui, Zhuo Tang

Bioscience Reports

DOI

2021

Sequence-specific and multiplex detection of COVID-19 virus (SARS-CoV-2) using proofreading enzyme-mediated probe cleavage coupled with isothermal amplification

Sheng Ding, Gang-Yi Chen, Yinghua Wei, Juan Dong, Feng Du, Xin Cui, Xin Huang, Zhuo Tang

Biosensors & bioelectronics

DOI

2019

Intracellular selection of trans-cleaving hammerhead ribozymes

Xin Huang, Yong-Yun Zhao, Qinlin Pu, Getong Liu, Yan Peng, Fei Wang, Gang-Yi Chen, Meiling Sun, Feng Du, Juan Dong, Xin Cui, Zhuo Tang, Xian-Ming Mo

Nucleic Acids Research

DOI

2019

One-step colorimetric genotyping of single nucleotide polymorphism using probe-enhanced loop-mediated isothermal amplification (PE-LAMP)

Sheng Ding, Rong Chen, Gang-Yi Chen, Mei Li, Jiayu Wang, Jiawei Zou, Feng Du, Juan Dong, Xin Cui, Xin Huang, Yun Deng, Zhuo Tang

Theranostics

DOI

2019

Recombinase assisted loop-mediated isothermal DNA amplification.

Gang-Yi Chen, Rong Chen, Sheng Ding, Mei Li, Jiayu Wang, Jiawei Zou, Feng Du, Juan Dong, Xin Cui, Xin Huang, Yun Deng, Zhuo Tang

In Analysis

DOI

2019

Polymerase Chain Reaction using “V” Shape Thermal Cycling Program

Rong Chen, Xu-Lou Lu, Mei Li, Gang-Yi Chen, Yun Deng, Feng Du, Juan Dong, Xin Huang, Xin Cui, Zhuo Tang

Theranostics

DOI

2019

Colorimetric Detection of Horse Meat Based on Loop-Mediated Isothermal Amplification (LAMP)

Jiayu Wang, Yu-Ping Wan, Gang-Yi Chen, Heng-Xing Liang, Sheng Ding, Ke Shang, Mei Li, Juan Dong, Feng Du, Xin Cui, Zhuo Tang

Food Analytical Methods

DOI

2018

Colorimetric PCR-Based microRNA Detection Method Based on Small Organic Dye and Single Enzyme.

Juan Dong, Gang-Yi Chen, Wei Wang, Xin Huang, Huipan Peng, Qinlin Pu, Feng Du, Xin Cui, Yun Deng, Zhuo Tang

Analytical Chemistry

DOI

2018

DNAzyme based visual detection of DNA methylation.

Mei Li, Lei Zhang, Gang-Yi Chen, Jing Zhou, Yi Yuan, Jiawei Zou, Ming-ming Yuan, Rong Chen, Feng Du, Xin Cui, Xin Huang, Juan Dong, Zhuo Tang

Chemical Communications

DOI

2018

Evolution of microbial biosensor based on functional RNA through fluorescence-activated cell sorting

Na Li, Xin Huang, Jiawei Zou, Gang-Yi Chen, Getong Liu, Mei Li, Juan Dong, Feng Du, Xin Cui, Zhuo Tang

DOI

2017

A Novel Colorimetric PCR-Based Biosensor for Detection and Quantification of Hepatitis B Virus.

Li Yang, Mei Li, Feng Du, Gang-Yi Chen, A. Yasmeen, Zhuo Tang

Methods in molecular biology

DOI

2017

Weigh Biomaterials by Quantifying Species-specific DNA with Real-time PCR

Rong Chen, Jiayu Wang, Yi Yuan, Yun Deng, Xianrong Lai, Feng Du, Juan Dong, Xin Huang, Xin Cui, Zhuo Tang

Scientific Reports

DOI

2017

Selective tumor cell death induced by irradiated riboflavin through recognizing DNA G–T mismatch

Yi Yuan, Yong-Yun Zhao, Lian-Qi Chen, Jia-Si Wu, Gang-Yi Chen, Sheng Li, Jiawei Zou, Rong Chen, Jian Wang, F. Jiang, Zhuo Tang

Nucleic Acids Research

DOI

2017

Re-characterization of hammerhead ribozymes as molecular tools for intermolecular RNA cleavage.

Getong Liu, Xin Huang, Qinlin Pu, Yong-Yun Zhao, Feng Du, Juan Dong, Xin Cui, Zhuo Tang

Organic and biomolecular chemistry

DOI

2016

Sequence-Specific Biosensing of DNA Target through Relay PCR with Small-Molecule Fluorophore.

A. Yasmeen, Feng Du, Yong-Yun Zhao, Juan Dong, Haodong Chen, Xin Huang, Xin Cui, Zhuo Tang

ACS Chemical Biology

DOI

2016

[Quantitative Analysis of Pinellia ternata in Banxia Decoction by PCR].

Chenglin Wu, Rong Chen, Wei Wang, Shao-rong Qin, Jia-Wen Yu, Zhuo Tang, Yun Deng

Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials

2016

A general solution for opening double-stranded DNA for isothermal amplification

Gang-Yi Chen, Juan Dong, Yi Yuan, Na Li, Xin Huang, Xin Cui, Zhuo Tang

Scientific Reports

DOI

2016

Methods of isothermally unlocking double-stranded DNA and preparing single stranded DNA

Zhuo Tang, Gang-Yi Chen

2016

Characterization of deoxyribozymes with site-specific oxidative cleavage activity against DNA obtained by in vitro selection.

Ming-Qi Wang, Juan Dong, Hua-Fan Zhang, Zhuo Tang

Organic and biomolecular chemistry

DOI

2015

Nicking enzyme-based isothermal strand displacement amplification

Shi-Qiong Deng, Juan Dong, Gang-Yi Chen, DU Feng, Jiawei Zou, Zhuo Tang

Chinese Journal of Applied and Environmental Biology

DOI

2015

Selection of Intracellularly Functional RNA Mimics of Green Fluorescent Protein Using Fluorescence-Activated Cell Sorting

Jiawei Zou, Xin Huang, Lei Wu, Gang-Yi Chen, Juan Dong, Xin Cui, Zhuo Tang

Journal of Molecular Evolution

DOI

2015

Sequence-specific RNA Photocleavage by Single-stranded DNA in Presence of Riboflavin

Yong-Yun Zhao, Gang-Yi Chen, Yi Yuan, Na Li, Juan Dong, Xin Huang, Xin Cui, Zhuo Tang

Scientific Reports

DOI

2014

A novel colorimetric PCR-based biosensor for detection and quantification of hepatitis B virus.

Li Yang, Feng Du, Gang-Yi Chen, A. Yasmeen, Zhuo Tang

Analytica Chimica Acta

DOI

2014

Signal amplification of glucosamine-6-phosphate based on ribozyme glmS.

Yong-Yun Zhao, Haodong Chen, Feng Du, A. Yasmeen, Juan Dong, Xin Cui, Zhuo Tang

Biosensors & bioelectronics

DOI

2014

In vitro selection of DNA-cleaving deoxyribozyme with site-specific thymidine excision activity

Ming-Qi Wang, Hua-Fan Zhang, Wei Zhang, Yong-Yun Zhao, A. Yasmeen, Li Zhou, Xiaoqi Yu, Zhuo Tang

Nucleic Acids Research

DOI

2014

Template-directed Chemical Ligation to Obtain 3′-3′ and 5′-5′ Phosphodiester DNA Linkages

Haodong Chen, Feng Du, Gang-Yi Chen, Frank Streckenbach, A. Yasmeen, Yun Zhao, Zhuo Tang

Scientific Reports

DOI

2013

RNA pathogen detection with one-step reverse transcription PCR and strand-displacement based signal amplification.

Feng Du, Frank Streckenbach, Haodong Chen, Xin Huang, Zhuo Tang, A. Marx

In Analysis

DOI

2013

Cleavage-based signal amplification of RNA

Yong-Yun Zhao, Li Zhou, Zhuo Tang

Nature Communications

DOI

2013

DNAzyme based gap-LCR detection of single-nucleotide polymorphism.

Li Zhou, Feng Du, Yong-Yun Zhao, Afshan Yameen, Haodong Chen, Zhuo Tang

Biosensors & bioelectronics

DOI

2013

In Vitro Selection of DNA-cleaving DNAzyme: In Vitro Selection of DNA-cleaving DNAzyme

Hua-Fan Zhang, Ming-Qi Wang, Haodong Chen, Juan Dong, Feng Du, Li Zhou, Zhuo Tang

DOI

2013

DNA display for drug discovery

Haodong Chen, Gang-Yi Chen, Feng Du, Qingquan Fu, Yun Zhao, Zhuo Tang

DOI

2012

DNA based identification of medicinal materials in Chinese patent medicines

Rong Chen, Juan Dong, Xin Cui, Wei Wang, A. Yasmeen, Yun Deng, Xiaomao Zeng, Zhuo Tang

Scientific Reports

DOI

2012

Amplified detection of nucleic acid by G-quadruplex based hybridization chain reaction.

Juan Dong, Xin Cui, Yun-Liang Deng, Zhuo Tang

Biosensors & bioelectronics

DOI

2011

Colorimetric Detection of PCR Product with DNAzymes Induced by 5′‐Nuclease Activity of DNA Polymerases

Feng Du, Zhuo Tang

ChemBioChem

DOI

2011

Site-selective DNA hydrolysis induced by a metal-free peptide nucleic acid-cyclen conjugate.

Ming-Qi Wang, Jun-Liang Liu, Jing-Yi Wang, Da-Wei Zhang, Ji Zhang, Frank Streckenbach, Zhuo Tang, Hong-hui Lin, Yan Liu, Yufen Zhao, Xiao-Qi Yu

Chemical Communications

DOI

会议论文

2016

两例生物启发的有机合成方法学（英文）

Zhuo Tang, Guangxun Li

《中国化学会第30届学术年会摘要集-第九分会：有机化学》

2005

手性脯氨酰胺催化氯代丙酮与醛的不对称直接Aldol反应

何龙，唐卓，寸琳峰，宓爱巧，蒋耀忠，龚流柱

《中国化学会第四届有机化学学术会议论文集（上册）》

2005

脯氨酰胺类有机小分子催化的醛与羟基丙酮之间的直接Aldol反应

陈小华，唐卓，寸琳锋，宓爱巧，蒋耀忠，龚流柱

《中国化学会第四届有机化学学术会议论文集（上册）》

研究方向

药物化学基因检测基因编辑

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