张艳秋｜中国药科大学｜学者主页

2026

当归补血汤通过调节PPARγ信号通路改善代谢障碍相关脂肪性肝病

郑姝，黄定娴，张艳秋，田鑫，李明，张浩

《药学学报》

2025

Nodosin alleviates cholestatic liver injury by activation of SIRT1/FXR signaling pathway and inhibition of hepatic inflammation

Mingzhu Han, Yang Cheng, Wenli Wang, Shengtao Ye, Lingyi Kong, Yanqiu Zhang, Hao Zhang

Biochemical Pharmacology

DOI

2025

Targeting USP18 overcomes acquired resistance in hepatocellular carcinoma by regulating NCOA4 deISGylation and ferroptosis

Shengtao Ye, Junxin Chen, Ying Yi Zheng, Mengmeng He, Yanqiu Zhang, Cheng Yang, Yingrong Leng, Enyi Wu, Lingyi Kong, Hao Zhang

Cell Death and Disease

DOI

2024

LIX1L aggravates MASH-HCC progression by reprogramming of hepatic metabolism and microenvironment via CD36

Yingrong Leng, Yanqiu Zhang, Cheng Wei Yang, Shengtao Ye, Ying Yi Zheng, Mengmeng He, Enyi Wu, Lingyi Kong, Hao Zhang

Pharmacological Research

DOI

2024

The Flavonoid Glycoside from Abrus cantoniensis Hance Alleviates Alcoholic Liver Injury by Inhibiting Ferroptosis in an AMPK-Dependent Manner

Yanqiu Zhang, Ruirui Dong, Huiling Zhou, Jingyi Wang, Jianfei Shi, Shengtao Ye, Yang Cheng, Yingrong Leng, Wenjun Xu, Lingyi Kong, Hao Zhang

Journal of Agricultural and Food Chemistry

DOI

2024

Lefamulin Overcomes Acquired Drug Resistance via Regulating Mitochondrial Homeostasis by Targeting ILF3 in Hepatocellular Carcinoma

Ying Zheng, Shengtao Ye, Shiyu Huang, Yang Cheng, Yanqiu Zhang, Yingrong Leng, Mengmeng He, Enyi Wu, Junxin Chen, Lingyi Kong, Hao Zhang

Advanced Science

DOI

2023

大萼金丝桃素B抑制mTORC1信号通路改善非酒精性脂肪肝炎的作用和机制研究

张艳秋，何蒙蒙，李学炎，徐文军，张浩

《药学学报》

DOI

2023

天麻素对儿童多发性抽动症模型大鼠5-羟色胺系统的影响及相关机制

董博，孔敏，宋莹，姜宁，李慧，张艳秋，张峰

《山东医药》

2022

RNA helicase DEAD‐box protein 5 alleviates nonalcoholic steatohepatitis progression via tethering TSC complex and suppressing mTORC1 signaling

Yanqiu Zhang, Shengtao Ye, Wei-Jia Lu, Jiawen Zhong, Yingrong Leng, Ting Yang, Jun Luo, Wen‐Jun Xu, Hao Zhang, Ling‐Yi Kong

Hepatology

DOI

2022

Chlospicenes A and B, cyclopropane cracked lindenane sesquiterpenoid dimers with anti-nonalcoholic steatohepatitis activity from Chloranthus henryi

Jixin Li, Zhirong Cui, Yongyi Li, Chunhua Han, Yanqiu Zhang, Pengfei Tang, Letian Cui, Hao Zhang, Jun Luo, Lingyi Kong

Chinese Chemical Letters

DOI

2021

Ghrelin受体拮抗剂对糖尿病大鼠肝功能的调节及血管功能的保护作用

王晓军，张艳秋，翟铁

《中国现代应用药学》

2021

Hyperbenzones A and B, two 1,2-seco and rearranged polycyclic polyprenylated acylphloroglucinols from Hypericum beanii

Wei-Jia Lu, Yanqiu Zhang, Yawei Li, Shengtao Ye, Jun Luo, Lingyi Kong, Wen‐Jun Xu

Chinese Chemical Letters

DOI

2021

LIX1-like protein drives hepatic stellate cell activation to promote liver fibrosis by regulation of chemokine mRNA stability

Xiaoyun Zhu, Yanqiu Zhang, Yucheng Zhao, Dejuan Xiang, Jie Zou, OURANIA M. ANDRISANI, Hao Zhang, Ling‐Yi Kong

Signal Transduction and Targeted Therapy

DOI

2021

Physalin B attenuates liver fibrosis via suppressing LAP2α–HDAC1‐mediated deacetylation of the transcription factor GLI1 and hepatic stellate cell activation

Xiaoyun Zhu, Shengtao Ye, Dongke Yu, Yanqiu Zhang, Jie Li, Meihui Zhang, Yingrong Leng, Ting Yang, Jian‐Guang Luo, Xinlin Chen, Hao Zhang, Ling‐Yi Kong

British Journal of Pharmacology

DOI

2021

Diverse Polycyclic Polyprenylated Acylphloroglucinol Congeners with Anti-Nonalcoholic Steatohepatitis Activity from Hypericum forrestii

Wei-Jia Lu, Wen‐Jun Xu, Meihui Zhang, Yanqiu Zhang, Yiran Li, Hao Zhang, Jun Luo, Lingyi Kong

Journal of Natural Products

DOI

2021

Limb expression 1-like (LIX1L) protein promotes cholestatic liver injury by regulating bile acid metabolism

Jie Li, Xiaoyun Zhu, Meihui Zhang, Yanqiu Zhang, Shengtao Ye, Yingrong Leng, Ting Yang, Ling‐Yi Kong, Hao Zhang

Journal of Hepatology

DOI

2021

Tribbles homolog 2 promotes hepatic fibrosis and hepatocarcinogenesis through phosphatase 1A‐Mediated stabilization of yes‐associated protein

Dejuan Xiang, Xiaoyun Zhu, Yanqiu Zhang, Jie Zou, Jie Li, Ling‐Yi Kong, Hao Zhang

Liver International

DOI

2020

荔枝核多糖的水提醇沉工艺优化及其对α-葡萄糖苷酶的抑制活性研究

张艳秋，郑炜，刘凯青，曲文笛，冯晨曦，徐多多

《中国药房》

2020

Physalin B ameliorates nonalcoholic steatohepatitis by stimulating autophagy and NRF2 activation mediated improvement in oxidative stress

Meihui Zhang, Jie Li, Xiaoyun Zhu, Yanqiu Zhang, Sheng-tao Ye, Yingrong Leng, Ting Yang, Hao Zhang, Ling‐Yi Kong

Free Radical Biology and Medicine

DOI

2020

Hyperforones A–C, benzoyl-migrated [5.3.1]-type polycyclic polyprenylated acylphloroglucinols from Hypericum forrestii

Wei-Jia Lu, Wen‐Jun Xu, Yanqiu Zhang, Yiran Li, Xin Zhou, Qi‐Ji Li, Hao Zhang, Jun Luo, Lingyi Kong

Organic Chemistry Frontiers

DOI

2019

猴头菌多糖对溃疡性结肠炎模型大鼠肠道短链脂肪酸含量的影响

杨永刚，王丹丹，张艳秋，王明星

《中国药房》

2019

不同产地知母药材的含量测定及指纹图谱研究

陈素娟，张艳秋，聂静，杨芊芊，高歌，张旗，韩晶晶，蔡程科，李强

《西北药学杂志》

2019

基于Blackboard平台的麻醉药理学题库构建与应用研究

姜祖波，张艳秋，隽兆东，张蕊，梁映霞

《中国高等医学教育》

2019

Hyperberins A and B, Type B Polycyclic Polyprenylated Acylphloroglucinols with Bicyclo[5.3.1]hendecane Core from Hypericum beanii

Wen‐Jun Xu, Peng-Fei Tang, Wei-Jia Lu, Yanqiu Zhang, Xiaobing Wang, Hao Zhang, Jun Luo, Lingyi Kong

Organic Letters

DOI

2018

熟地黄饮片标准汤剂的质量标准研究

陈素娟，聂静，张旗，张艳秋，杨芊芊，高歌，雷海民，蔡程科，李强

《现代药物与临床》

2018

DEAD Box Protein 5 Inhibits Liver Tumorigenesis by Stimulating Autophagy via Interaction with p62/SQSTM1

Hao Zhang, Yanqiu Zhang, Xiaoyun Zhu, Chen Chen, Chao Zhang, Yuan‐Zheng Xia, Yucheng Zhao, OURANIA M. ANDRISANI, Ling‐Yi Kong

Hepatology

DOI

2018

A double-negative feedback loop between DEAD-box protein DDX21 and Snail regulates epithelial-mesenchymal transition and metastasis in breast cancer

Hao Zhang, Yanqiu Zhang, Chen Chen, Xiaoyun Zhu, Chao Zhang, Yuan‐Zheng Xia, Yucheng Zhao, OURANIA M. ANDRISANI, Ling‐Yi Kong

Cancer Letters

DOI

2018

Cipadessains A–K, eleven limonoids from the fruits of Cipadessa cinerascens

Dongmei Sun, Faliang An, Shanshan Wei, Yanqiu Zhang, Xiaobing Wang, Jun Luo, Ling‐Yi Kong

RSC Advances

DOI

2016

非线性化学指纹图谱技术对药用植物不同部位质量的评价

罗时旋，李守君，滕杨，张艳秋，李莉，武静茹

《黑龙江医药科学》

2015

蒙药“孟根乌苏-18”染毒对银屑病小鼠细胞因子的影响

史勇，李冬梅，张艳秋，肖井雷，王戬萌

《毒理学杂志》

2011

七种中草药电化学指纹图谱研究

张艳秋，陈伟秋，罗时旋，武静茹，郑伟超，李莉，李守君

《佳木斯大学学报(自然科学版)》

2011

中药制剂皲裂霜的毒理和药理学研究

张艳秋，何心

《首都食品与医药》

2010

中药大黄电化学指纹图谱研究

张秀莉，佟德成，李守君，黄金宝，张艳秋

《黑龙江医药科学》

2009

多柔比星白蛋白微球的生物性质及其在大鼠体内的分布

张艳秋，潘志，徐多多，高阳，姜瑞芝，陈映红，高其品

《中国药房》

2008

商品肉豆蔻药材的指纹图谱研究

袁子民，贾天柱，张艳秋，祖凤英

《中国中医药信息杂志》

2004

贯黄感冒颗粒(无糖型)质量标准研究

张艳秋，梁其冰

《中国现代应用药学》

2003

固本回元口服液质量标准的研究

张艳秋，梁其冰

《中药新药与临床药理》

2002

水杨酸磷酸酯的药理学研究

高锐，张艳秋

《黑龙江医药》

1998

盐酸甜菜碱在大鼠体内药物代谢动力学及分布

王桂芳，李伟，陈颖莉，张艳秋，曲淑岩

《中国药理学与毒理学杂志》

1997

高效液相色谱法测定双黄连粉针中绿原酸和咖啡酸的含量

何心，石春伟，芦松萍，张艳秋，郡修德，井关键，宫崎胜已

《药物分析杂志》

1990

醋柳愈酯临床药代动力学及相对生物利用度研究

李伟，曲淑岩，陈颖莉，张艳秋，宋宗明

《中国临床药理学杂志》

1990

高山红景天的微量元素和氨基酸含量分析

张艳秋，王兆华，牛志多，王淑琴

《中草药》

精选作品

期刊论文

当归补血汤通过调节PPARγ信号通路改善代谢障碍相关脂肪性肝病

Nodosin alleviates cholestatic liver injury by activation of SIRT1/FXR signaling pathway and inhibition of hepatic inflammation

Targeting USP18 overcomes acquired resistance in hepatocellular carcinoma by regulating NCOA4 deISGylation and ferroptosis

LIX1L aggravates MASH-HCC progression by reprogramming of hepatic metabolism and microenvironment via CD36

The Flavonoid Glycoside from Abrus cantoniensis Hance Alleviates Alcoholic Liver Injury by Inhibiting Ferroptosis in an AMPK-Dependent Manner

Lefamulin Overcomes Acquired Drug Resistance via Regulating Mitochondrial Homeostasis by Targeting ILF3 in Hepatocellular Carcinoma

大萼金丝桃素B抑制mTORC1信号通路改善非酒精性脂肪肝炎的作用和机制研究

天麻素对儿童多发性抽动症模型大鼠5-羟色胺系统的影响及相关机制

RNA helicase DEAD‐box protein 5 alleviates nonalcoholic steatohepatitis progression via tethering TSC complex and suppressing mTORC1 signaling

Chlospicenes A and B, cyclopropane cracked lindenane sesquiterpenoid dimers with anti-nonalcoholic steatohepatitis activity from Chloranthus henryi

Ghrelin受体拮抗剂对糖尿病大鼠肝功能的调节及血管功能的保护作用

Hyperbenzones A and B, two 1,2-seco and rearranged polycyclic polyprenylated acylphloroglucinols from Hypericum beanii

LIX1-like protein drives hepatic stellate cell activation to promote liver fibrosis by regulation of chemokine mRNA stability

Physalin B attenuates liver fibrosis via suppressing LAP2α–HDAC1‐mediated deacetylation of the transcription factor GLI1 and hepatic stellate cell activation

Diverse Polycyclic Polyprenylated Acylphloroglucinol Congeners with Anti-Nonalcoholic Steatohepatitis Activity from Hypericum forrestii

Limb expression 1-like (LIX1L) protein promotes cholestatic liver injury by regulating bile acid metabolism

Tribbles homolog 2 promotes hepatic fibrosis and hepatocarcinogenesis through phosphatase 1A‐Mediated stabilization of yes‐associated protein

荔枝核多糖的水提醇沉工艺优化及其对α-葡萄糖苷酶的抑制活性研究

Physalin B ameliorates nonalcoholic steatohepatitis by stimulating autophagy and NRF2 activation mediated improvement in oxidative stress

Hyperforones A–C, benzoyl-migrated [5.3.1]-type polycyclic polyprenylated acylphloroglucinols from Hypericum forrestii

猴头菌多糖对溃疡性结肠炎模型大鼠肠道短链脂肪酸含量的影响

不同产地知母药材的含量测定及指纹图谱研究

基于Blackboard平台的麻醉药理学题库构建与应用研究

Hyperberins A and B, Type B Polycyclic Polyprenylated Acylphloroglucinols with Bicyclo[5.3.1]hendecane Core from Hypericum beanii

熟地黄饮片标准汤剂的质量标准研究

DEAD Box Protein 5 Inhibits Liver Tumorigenesis by Stimulating Autophagy via Interaction with p62/SQSTM1

A double-negative feedback loop between DEAD-box protein DDX21 and Snail regulates epithelial-mesenchymal transition and metastasis in breast cancer

Cipadessains A–K, eleven limonoids from the fruits of Cipadessa cinerascens

非线性化学指纹图谱技术对药用植物不同部位质量的评价

蒙药“孟根乌苏-18”染毒对银屑病小鼠细胞因子的影响

七种中草药电化学指纹图谱研究

中药制剂皲裂霜的毒理和药理学研究

中药大黄电化学指纹图谱研究

多柔比星白蛋白微球的生物性质及其在大鼠体内的分布

商品肉豆蔻药材的指纹图谱研究

贯黄感冒颗粒(无糖型)质量标准研究

固本回元口服液质量标准的研究

水杨酸磷酸酯的药理学研究

盐酸甜菜碱在大鼠体内药物代谢动力学及分布

高效液相色谱法测定双黄连粉针中绿原酸和咖啡酸的含量

醋柳愈酯临床药代动力学及相对生物利用度研究

高山红景天的微量元素和氨基酸含量分析

会议论文

多壁碳纳米管经气管滴注染毒大鼠血清的代谢组学研究

纳米二氧化钛对RAW264.7细胞的miRNAs调控及机制研究

纳米二氧化钛对大鼠免疫毒性效应

胡椒与市售胡椒粉FTIR指纹图谱对比分析

关于中药指纹图谱的研究概述

胡椒与市售胡椒粉HPLC指纹图谱分析

木麻黄质量标准的初步研究