范西莹｜陕西师范大学｜学者主页

2025

Nanobodies in Immunoanalysis: From Molecular Engineering to Advanced Detection Strategies for Foodborne Natural Toxins.

Xiying Fan, Yibo Gong, Wenshuai Liu, Kong-Peng Lam, Shengli Xu, Song Xue, Nian Rui

Chemistry

DOI

2024

Novel Polystyrene-Binding Nanobody for Enhancing Immunoassays: Insights into Affinity, Immobilization, and Application Potential.

Yang Deng, Jinyan Liu, Yaoping Lu, Xiying Fan, Yuansheng Yang, Yaozheng Xu, Xiao-Song Qin, Nian Rui, Wenshuai Liu

Analytical Chemistry

DOI

2024

A comprehensive review of engineered exosomes from the preparation strategy to therapeutic applications.

Xiying Fan, Yiwen Zhang, Wenshuai Liu, Mingzheng Shao, Yibo Gong, Ting-Ya Wang, Song Xue, Nian Rui

Biomaterials Science

DOI

2024

Streamlined on-column refolding and purification of nanobodies from inclusion bodies expressed as fusion proteins.

Yiwen Zhang, Yang Guo, Liang Song, Wenshuai Liu, Nian Rui, Xiying Fan

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

DOI

2023

气候要素影响下老年人死亡风险表现及适应水平差异分析

范西莹，李晶晶

《人口研究》，Vol. 47, No. 5

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2023

Optimized silk fibroin nanoparticle functionalization with anti-CEA nanobody enhancing active targeting of colorectal cancer cells

Xiying Fan, Xin-Ying Peng, Ting-Ting Wang, Yi Gu, Guochuan Sun, Qinghui Shou, Hai-Peng Song, Nian Rui, Wenshuai Liu

Biomedical Materials

DOI

2022

A novel silk fibroin protein–based fusion system for enhancing the expression of nanobodies in Escherichia coli

Jianli Yu, Yang Guo, Yi Gu, Xiying Fan, Fei Li, Hai-Peng Song, Nian Rui, Wenshuai Liu

Applied Microbiology and Biotechnology

DOI

2022

Targeting and neutralizing human epididymis protein 4 by novel nanobodies to suppress ovarian cancer cells and attenuate cisplatin resistance.

Jianli Yu, Yang Guo, Yi Gu, Fei Li, Hai-Peng Song, Nian Rui, Xiying Fan, Wenshuai Liu

International Journal of Biological Macromolecules

DOI

2020

Development and characterization of a photo-cross-linked functionalized type-I collagen (Oreochromis niloticus) and polyethylene glycol diacrylate hydrogel.

Zixian Bao, Minghong Gao, Xiying Fan, Yuting Cui, Junqing Yang, Xin-Ying Peng, M. Xian, Yue Sun, Nian Rui

International Journal of Biological Macromolecules

DOI

2020

Development of tilapia collagen and chitosan composite hydrogels for nanobody delivery.

Xiying Fan, Yunlong Liang, Yuting Cui, Fei Li, Yue Sun, Junqing Yang, Hai-Peng Song, Zixian Bao, Nian Rui

Colloids and Surfaces B: Biointerfaces

DOI

2019

Reduction of chromatin heteroaggregates by acid precipitation of mammalian cell culture and ramification in protein A chromatography for recombinant immunoglobulin G purification

Wenshuai Liu, Dongyan Zhou, Yue Sun, Jianli Yu, Quan Chen, Zixian Bao, Xiying Fan, Yunlong Liang, Xin-Ying Peng, M. Xian, Nian Rui

Biochemical engineering journal

DOI

2019

Integrated purification of a nanobody using ammonium sulfate precipitation and Capto MMC

Xiying Fan, Yunlong Liang, Fei Li, Jianli Yu, Hai-Peng Song, Dongxiao Feng, M. Xian, Wenshuai Liu, Nian Rui

Journal of Chemical Technology & Biotechnology

DOI

2019

Advance chromatin extraction improves the performance of electropositive mixed-mode chromatography as a capture step and enables its integration with void-exclusion anion exchange chromatography as a two-column-step purification platform for monoclonal antibody production

Wenshuai Liu, Yue Sun, Jianli Yu, Quan Chen, Zixian Bao, Xiying Fan, Yunlong Liang, Xin-Ying Peng, M. Xian, Nian Rui

Biochemical engineering journal

DOI

2019

Non-affinity purification of a nanobody by void-exclusion anion exchange chromatography and multimodal weak cation exchange chromatography

Xiying Fan, Yu-Hang Zhou, Jianli Yu, Fei Li, Quan Chen, Hai-Peng Song, Dongxiao Feng, Wenshuai Liu, Nian Rui, M. Xian

Separation and Purification Technology

DOI

2019

A seamless and nonprotein A‐based monoclonal antibody purification platform using void‐exclusion anion exchange chromatography and electropositive multimodal chromatography enhanced by advance chromatin extraction

Wenshuai Liu, Quan Chen, Xiying Fan, Yunlong Liang, Yue Sun, Jianli Yu, Zixian Bao, Xin-Ying Peng, M. Xian, Nian Rui

Journal of Chemical Technology & Biotechnology

DOI

2019

Chromatin-directed clarification in cell culture fluid enables non-protein affinity antibody purification by tangential flow filtration integrated with high-capacity cation exchange chromatography

Wenshuai Liu, Xiying Fan, Xingang Wang, K. Rai, Jianhua Su, M. Xian, Nian Rui

Biochemical engineering journal

DOI

2019

Salt-enhanced permeabilization for monoclonal antibody precipitation and purification in a tubular reactor with a depth filtration membrane with advanced chromatin extraction

Wenshuai Liu, Xiying Fan, Xingang Wang, Zixian Bao, Yue Sun, K. Rai, A. Shaliutina‐Kolešová, Jianhua Su, M. Xian, Nian Rui

Biochemical engineering journal

DOI

2017

中国老人选择机构养老的质性研究

王琪，詹合英，范西莹

《人口与社会》

2013

社会资本进入我国养老服务业的结构性差异分析——以民办养老机构为例

范西莹

《西安财经大学学报》

2013

政策性支持对于我国民办养老机构发展的推助作用分析

范西莹

《甘肃理论学刊》

2009

血亲价值观及中国老年人对非正式支持资源的选择研究

姚远，范西莹

《中州学刊》，No. 2

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2009

从尊老养老文化内涵的变化看我国调整制定老龄政策基本原则的必要性

姚已远，范西莹

《人口与发展》，No. 2

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2009

从我国弱势群体的弱势特征看社会政策支助体系的设计框架——基于北京市老年残疾人视角的分析

姚远，范西莹

《南方人口》

2008

陕西省城乡居民生活质量分析

白琳，张琳，邵敏，范西莹

《西安邮电大学学报》

范西莹

精选作品

期刊论文

Nanobodies in Immunoanalysis: From Molecular Engineering to Advanced Detection Strategies for Foodborne Natural Toxins.

Novel Polystyrene-Binding Nanobody for Enhancing Immunoassays: Insights into Affinity, Immobilization, and Application Potential.

A comprehensive review of engineered exosomes from the preparation strategy to therapeutic applications.

Streamlined on-column refolding and purification of nanobodies from inclusion bodies expressed as fusion proteins.

气候要素影响下老年人死亡风险表现及适应水平差异分析

Optimized silk fibroin nanoparticle functionalization with anti-CEA nanobody enhancing active targeting of colorectal cancer cells

A novel silk fibroin protein–based fusion system for enhancing the expression of nanobodies in Escherichia coli

Targeting and neutralizing human epididymis protein 4 by novel nanobodies to suppress ovarian cancer cells and attenuate cisplatin resistance.

Development and characterization of a photo-cross-linked functionalized type-I collagen (Oreochromis niloticus) and polyethylene glycol diacrylate hydrogel.

Development of tilapia collagen and chitosan composite hydrogels for nanobody delivery.

Reduction of chromatin heteroaggregates by acid precipitation of mammalian cell culture and ramification in protein A chromatography for recombinant immunoglobulin G purification

Integrated purification of a nanobody using ammonium sulfate precipitation and Capto MMC

Advance chromatin extraction improves the performance of electropositive mixed-mode chromatography as a capture step and enables its integration with void-exclusion anion exchange chromatography as a two-column-step purification platform for monoclonal antibody production

Non-affinity purification of a nanobody by void-exclusion anion exchange chromatography and multimodal weak cation exchange chromatography

A seamless and nonprotein A‐based monoclonal antibody purification platform using void‐exclusion anion exchange chromatography and electropositive multimodal chromatography enhanced by advance chromatin extraction

Chromatin-directed clarification in cell culture fluid enables non-protein affinity antibody purification by tangential flow filtration integrated with high-capacity cation exchange chromatography

Salt-enhanced permeabilization for monoclonal antibody precipitation and purification in a tubular reactor with a depth filtration membrane with advanced chromatin extraction

中国老人选择机构养老的质性研究

社会资本进入我国养老服务业的结构性差异分析——以民办养老机构为例

政策性支持对于我国民办养老机构发展的推助作用分析

血亲价值观及中国老年人对非正式支持资源的选择研究

从尊老养老文化内涵的变化看我国调整制定老龄政策基本原则的必要性

从我国弱势群体的弱势特征看社会政策支助体系的设计框架——基于北京市老年残疾人视角的分析

陕西省城乡居民生活质量分析

会议论文

北京市民办养老服务机构发展状况及特征分析

研究方向