宗冰冰｜武汉轻工大学｜学者主页

2026

IL-17 signaling pathway in monocytes drives the persistent inflammatory cytokine storm caused by Glaesserella parasuis infection in pigs.

Peiyi Wang, Aihua Wu, Jianing Niu, Wei Liu, Shulin Fu, Yan-Yan Zhang, Bing-Bing Zong, Yinsheng Qiu

Veterinary Microbiology

DOI

2025

黄芩苷通过抗炎机制降低猪源肠外致病性大肠杆菌感染损伤

刘微，任明星，王培懿，肖涌，吴爱华，张焱焱，付书林，邱银生，宗冰冰

《微生物学报》

DOI

2025

The Regulatory Role of EvfG Through Coordinated Control of Flagellar Biosynthesis and Energy Metabolism in Porcine Extraintestinal Pathogenic Escherichia coli (ExPEC)

Bing-Bing Zong, Peiyi Wang, Wei Liu, Aihua Wu, Yong Xiao, Shulin Fu, Yinsheng Qiu, Yanyan Zhang, Wen-Tong Liu

Biology

DOI

2025

Comparative study of the effects of baicalin and probenecid on microRNA expression profiles in porcine aortic vascular endothelial cells infected by Glaesserella parasuis

Ling Guo, Ya-Qiong Yang, Lin-Rong Yang, Peiyan Sun, Jing He, Shulin Fu, Chun Ye, Bing-Bing Zong, Yinsheng Qiu

BMC Veterinary Research

DOI

2024

PD-1/PD-L1 axis induced host immunosuppression via PI3K/Akt/mTOR signalling pathway in piglets infected by Glaesserella Parasuis

Jingyang Li, Siyu Liu, Qiaoli Dong, Yunjian Fu, Ya-Min Sun, Ronghui Luo, Xinyue Tian, Ling Guo, Wei Liu, Yinsheng Qiu, Qi-Rong Lu, Chun Ye, Bing-Bing Zong, Shulin Fu

BMC Veterinary Research

DOI

2024

Baicalin and probenecid protect against Glaesserella parasuis challenge in a piglet model

Shulin Fu, Siyu Liu, Jingyang Li, Qiaoli Dong, Yunjian Fu, Ronghui Luo, Ya-Min Sun, Xinyue Tian, Wei Liu, Bing-Bing Zong, Chun Ye, Qi-Rong Lu, Yinsheng Qiu, Ling Guo

Veterinary Research

DOI

2024

LAMTOR1/mTORC1 promotes CD276 to induce immunosuppression via PI3K/Akt/MMP signaling pathway in Clostridium perfringens–induced necrotic enteritis of laying hens

Qiaoli Dong, Ya-Min Sun, Jingyang Li, Xinyue Tian, Siyu Liu, Yunjian Fu, Ronghui Luo, Ling Guo, Bing-Bing Zong, Qi-Rong Lu, Chun Ye, Shulin Fu, Yinsheng Qiu

Poultry Science

DOI

2024

EvfG is a multi-function protein located in the Type VI secretion system for ExPEC.

Wen-Jia Lu, Hao Lu, X. Huo, Chen-Chen Wang, Zhao-Ran Zhang, Bing-Bing Zong, Gao-Yan Wang, W. Dong, Xiao-Dan Li, Yuying Li, Huan-Chun Chen, Chen Tan

Microbiology Research

DOI

2024

Baicalin Weakens the Virulence of Porcine Extraintestinal Pathogenic Escherichia coli by Inhibiting the LuxS/AI-2 Quorum-Sensing System

Bing-Bing Zong, Yong Xiao, Peiyi Wang, Wei Liu, Mingxing Ren, Chang Li, Shulin Fu, Yanyan Zhang, Yinsheng Qiu

Biomolecules

DOI

2023

黄芩苷对猪源肠外致病性大肠杆菌的体内保护作用

任明星，肖涌，付书林，宗冰冰，邱银生

《湖北农业科学》

2023

Baicalin Attenuated PANX-1/P2X7 Axis, P2Y6, and NLRP3/Caspase-1 Signaling Pathways in Peritonitis Induced by Glaesserella parasuis

Shulin Fu, Xinyue Tian, Jingyang Li, Yuzhen Yuan, Xiaoyi Li, Mingxing Ren, Ling Guo, Chun Ye, Bing-Bing Zong, Yu Liu, Qirong Lu, Yinsheng Qiu

Microbiology Research

DOI

2023

Transcriptome and metabolome profiling to elucidate the mechanism underlying the poor growth of Streptococcus suis serotype 2 after orphan response regulator CovR deletion

Bing-Bing Zong, Yong Xiao, Rui Li, Huanhuan Li, Peiyi Wang, Xiaopei Yang, Yanyan Zhang

Frontiers in Veterinary Science

DOI

2023

Metagenomic Sequencing Analysis of the Effects of Acetylcysteine on the Pig Gut Microbiome

Shulin Fu, Xinyue Tian, Jingyang Li, Yuzhen Yuan, Jing He, Chun Peng, Ling Guo, Chun Ye, Yu Liu, Bing-Bing Zong, Yinsheng Qiu

Microbiology Research

DOI

2023

Baicalin inhibited PANX-1/P2Y6 signaling pathway activation in porcine aortic vascular endothelial cells infected by Glaesserella parasuis

Shulin Fu, Xinyue Tian, Chun Peng, Dan Zhang, Linglu Zhou, Yuzhen Yuan, Jing He, Ling Guo, Yinsheng Qiu, Chun Ye, Yu Liu, Bing-Bing Zong

Heliyon

DOI

2023

Orphan response regulator CovR plays positive regulative functions in the survivability and pathogenicity of Streptococcus suis serotype 2 isolated from a pig

Yanyan Zhang, Rui Li, Qian Li, Yong-Wei Zhu, Xiaopei Yang, Di Zhao, Bing-Bing Zong

BMC Veterinary Research

DOI

2023

Baicalin Weakens the Porcine ExPEC-Induced Inflammatory Response in 3D4/21 Cells by Inhibiting the Expression of NF-κB/MAPK Signaling Pathways and Reducing NLRP3 Inflammasome Activation

Bing-Bing Zong, Yong Xiao, Mingxing Ren, Peiyi Wang, Shulin Fu, Yinsheng Qiu

Microorganisms

DOI

2022

Detection of Colistin Sulfate on Piglet Gastrointestinal Tract Microbiome Alterations

Shulin Fu, Yuzhen Yuan, Xinyue Tian, Linglu Zhou, Ling Guo, Dan Zhang, Jing He, Chun Peng, Yinsheng Qiu, Chun Ye, Yu Liu, Bing-Bing Zong

Veterinary Sciences

DOI

2022

Characteristics of Mycoplasma hyopneumoniae Strain ES-2 Isolated From Chinese Native Black Pig Lungs

Bing-Bing Zong, Yong-Wei Zhu, Man-Li Liu, Xiangru Wang, Huan-Chun Chen, Yanyan Zhang, Chen Tan

Frontiers in Veterinary Science

DOI

2021

“课程思政”融入动物传染病教学的路径初探

宗冰冰，张焱焱，邱银生

《大学》

2020

RcsB-dependent Regulation of Type VI Secretion System in Porcine Extra-intestinal Pathogenic Escherichia coli.

Lin-Lin Hu, Fei-Fei Yu, Man-Li Liu, J. Chen, Bing-Bing Zong, Yanyan Zhang, Tumei Chen, Chen-Chen Wang, Tong-Chao Zhang, Junli Zhang, Yong-Wei Zhu, Xiangru Wang, Huan-Chun Chen, Chen Tan

Gene

DOI

2019

Effect of O antigen ligase gene mutation on oxidative stress resistance and pathogenicity of NMEC strain RS218.

Yucheng Zheng, Huan Wang, Li-Ming Huang, Tong-Chao Zhang, Bing-Bing Zong, Xuanxiu Ren, Yong-Wei Zhu, Fangyu Song, Xiangru Wang, Huan-Chun Chen, Chen Tan

Microbial Pathogenesis

DOI

2019

Characterization of multiple type-VI secretion system (T6SS) VgrG proteins in the pathogenicity and antibacterial activity of porcine extra-intestinal pathogenic Escherichia coli

Bing-Bing Zong, Yanyan Zhang, Xiangru Wang, Man-Li Liu, Tong-Chao Zhang, Yong-Wei Zhu, Yucheng Zheng, Lin-Lin Hu, Pei Li, Huan-Chun Chen, Chen Tan

Virulence

DOI

2018

Fisetin Lowers Streptococcus suis serotype 2 Pathogenicity in Mice by Inhibiting the Hemolytic Activity of Suilysin

Yanyan Zhang, Bing-Bing Zong, Xiangru Wang, Yong-Wei Zhu, Lin-Lin Hu, Pei Li, Anding Zhang, Huan-Chun Chen, Man-Li Liu, Chen Tan

Frontiers in Microbiology

DOI

2017

Comparative Proteomics Analysis of Human Macrophages Infected with Virulent Mycobacterium bovis

Pei Li, Rui Wang, W. Dong, Lin-Lin Hu, Bing-Bing Zong, Yanyan Zhang, Xiangru Wang, A. Guo, Anding Zhang, Yao-Zu Xiang, Huan-Chun Chen, Chen Tan

Frontiers in Cellular and Infection Microbiology

DOI

2016

Effect of kpsM on the virulence of porcine extraintestinal pathogenic Escherichia coli.

Bing-Bing Zong, Wugang Liu, Yanyan Zhang, Xiangru Wang, Huan-Chun Chen, Chen Tan

FEMS Microbiology Letters

DOI

2016

Effect of the glycosyltransferases on the capsular polysaccharide synthesis of Streptococcus suis serotype 2.

Yanyan Zhang, D. Ding, Man-Li Liu, Xiaopei Yang, Bing-Bing Zong, Xiangru Wang, Huan-Chun Chen, Wei-Cheng Bei, Chen Tan

Microbiology Research

DOI

2016

Roles of Hcp family proteins in the pathogenesis of the porcine extraintestinal pathogenic Escherichia coli type VI secretion system

Ying Peng, Xiangru Wang, Jin Shou, Bing-Bing Zong, Yanyan Zhang, Jia Tan, Jing Chen, Lin-Lin Hu, Yong-Wei Zhu, Huan-Chun Chen, Chen Tan

Scientific Reports

DOI

宗冰冰

精选作品

期刊论文

IL-17 signaling pathway in monocytes drives the persistent inflammatory cytokine storm caused by Glaesserella parasuis infection in pigs.

黄芩苷通过抗炎机制降低猪源肠外致病性大肠杆菌感染损伤

The Regulatory Role of EvfG Through Coordinated Control of Flagellar Biosynthesis and Energy Metabolism in Porcine Extraintestinal Pathogenic Escherichia coli (ExPEC)

Comparative study of the effects of baicalin and probenecid on microRNA expression profiles in porcine aortic vascular endothelial cells infected by Glaesserella parasuis

PD-1/PD-L1 axis induced host immunosuppression via PI3K/Akt/mTOR signalling pathway in piglets infected by Glaesserella Parasuis

Baicalin and probenecid protect against Glaesserella parasuis challenge in a piglet model

LAMTOR1/mTORC1 promotes CD276 to induce immunosuppression via PI3K/Akt/MMP signaling pathway in Clostridium perfringens–induced necrotic enteritis of laying hens

EvfG is a multi-function protein located in the Type VI secretion system for ExPEC.

Baicalin Weakens the Virulence of Porcine Extraintestinal Pathogenic Escherichia coli by Inhibiting the LuxS/AI-2 Quorum-Sensing System

黄芩苷对猪源肠外致病性大肠杆菌的体内保护作用

Baicalin Attenuated PANX-1/P2X7 Axis, P2Y6, and NLRP3/Caspase-1 Signaling Pathways in Peritonitis Induced by Glaesserella parasuis

Transcriptome and metabolome profiling to elucidate the mechanism underlying the poor growth of Streptococcus suis serotype 2 after orphan response regulator CovR deletion

Metagenomic Sequencing Analysis of the Effects of Acetylcysteine on the Pig Gut Microbiome

Baicalin inhibited PANX-1/P2Y6 signaling pathway activation in porcine aortic vascular endothelial cells infected by Glaesserella parasuis

Orphan response regulator CovR plays positive regulative functions in the survivability and pathogenicity of Streptococcus suis serotype 2 isolated from a pig

Baicalin Weakens the Porcine ExPEC-Induced Inflammatory Response in 3D4/21 Cells by Inhibiting the Expression of NF-κB/MAPK Signaling Pathways and Reducing NLRP3 Inflammasome Activation

Detection of Colistin Sulfate on Piglet Gastrointestinal Tract Microbiome Alterations

Characteristics of Mycoplasma hyopneumoniae Strain ES-2 Isolated From Chinese Native Black Pig Lungs

“课程思政”融入动物传染病教学的路径初探

RcsB-dependent Regulation of Type VI Secretion System in Porcine Extra-intestinal Pathogenic Escherichia coli.

Effect of O antigen ligase gene mutation on oxidative stress resistance and pathogenicity of NMEC strain RS218.

Characterization of multiple type-VI secretion system (T6SS) VgrG proteins in the pathogenicity and antibacterial activity of porcine extra-intestinal pathogenic Escherichia coli

Fisetin Lowers Streptococcus suis serotype 2 Pathogenicity in Mice by Inhibiting the Hemolytic Activity of Suilysin

Comparative Proteomics Analysis of Human Macrophages Infected with Virulent Mycobacterium bovis

Effect of kpsM on the virulence of porcine extraintestinal pathogenic Escherichia coli.

Effect of the glycosyltransferases on the capsular polysaccharide synthesis of Streptococcus suis serotype 2.

Roles of Hcp family proteins in the pathogenesis of the porcine extraintestinal pathogenic Escherichia coli type VI secretion system

会议论文

黄芩苷对猪源肠外致病性大肠杆菌感染猪肺泡巨噬细胞炎性信号通路的影响

黄芩苷对猪源肠外致病性大肠杆菌感染细胞的保护作用

黄芩苷对副猪嗜血杆菌感染仔猪后腹膜和心包膜中CD分子表达的影响

研究方向