吴家雪｜重庆医科大学｜学者主页

2026

p300/CBP-Driven Acetylation Stabilizes PARP7 to Reinforce Negative Feedback on Type I Interferon Signaling

Dan Li, Yao Liu, Ying Wang, Wei-Jie Liu, Shi-Hui Zhu, Ying Zhang, Lu-Yi Wang, Xiaoqin Zhou, Wen Ding, Sanyong Zhu, Yong-Jun Dang, Jiaxue Wu

bioRxiv

DOI

2026

Beauvericin promotes autophagy and mitophagy by activating NIPSNAP2.

Xue Zhao, Ruihan Zhang, Yihan Ma, T. Yu, Jiao Li, An-di Liu, Jun-Chi Hu, Jiaxue Wu, Ling Zhang, Ming-Liang Ye, Bin Wu, Yong-Jun Dang

Bioorganic chemistry (Print)

DOI

2026

Single-cell-based identification of drug synergy with immunotherapy via tumor microenvironment remodeling

Ziruoyu Wang, Jun-Chi Hu, Kailu Liu, Jie Xu, Jiao Li, Yi-Hang Liu, Qinfeng Ma, Yuehan Dong, Yunmei Zhu, Kai Zhang, De-Xin Wang, Xiaobo Wang, Shuai Wang, Jianbo Pan, Shuai Jiang, Jiaxue Wu, Wei Jiang, Ling Zhang, Yong-Jun Dang

Journal for ImmunoTherapy of Cancer

DOI

2023

PARP15在肺腺癌中的表达及其对肺腺癌细胞生长、凋亡的影响

周晓敏，刘唯洁，吴家雪

《中国细胞生物学学报》

2022

PARP9促进肺腺癌细胞的迁移和侵袭

郑芬，周晓敏，吴家雪

《复旦学报(医学版)》

2020

Poly(ADP-ribosyl)ation mediates early phase histone eviction at DNA lesions

Guang Yang, Yibin Chen, Jiaxue Wu, Shih-Hsun Chen, Xiu-Hua Liu, Anup K. Singh, Xiaochun Yu

Nucleic Acids Research

DOI

2019

PARP1调节肝癌细胞的生长和迁移

游莉芳，魏莉，吴家雪

《复旦学报(自然科学版)》

DOI

2018

多聚ADP-核糖结合蛋白的鉴定

沈莉芳，张弛，吴家雪

《复旦学报(自然科学版)》

2013

RNF168 forms a functional complex with RAD6 during the DNA damage response

Chao Liu, De-Gui Wang, Jiaxue Wu, Jennifer A Keller, Teng Ma, Xiaochun Yu

Journal of Cell Science

DOI

2012

CHFR is important for the first wave of ubiquitination at DNA damage sites

Chao Liu, Jiaxue Wu, S. Paudyal, Zhong-Sheng You, Xiaochun Yu

Nucleic Acids Research

DOI

2012

RAP80 Protein Is Important for Genomic Stability and Is Required for Stabilizing BRCA1-A Complex at DNA Damage Sites in Vivo*

Jiaxue Wu, Chao Liu, Jun-Jie Chen, Xiaochun Yu

Journal of Biological Chemistry

DOI

2011

Chfr and RNF8 synergistically regulate ATM activation

Jiaxue Wu, Yibin Chen, Lin-Yu Lu, Yi-Pin Wu, M. Paulsen, M. Ljungman, D. Ferguson, Xiaochun Yu

Nature Structural &Molecular Biology

DOI

2010

RBX1 (RING Box Protein 1) E3 Ubiquitin Ligase Is Required for Genomic Integrity by Modulating DNA Replication Licensing Proteins*

L. Jia, J. Bickel, Jiaxue Wu, M. Morgan, Hua Li, Jie Yang, Xiaochun Yu, Raymond C. Chan, Yi Sun

Journal of Biological Chemistry

DOI

2010

RNF8-dependent histone modifications regulate nucleosome removal during spermatogenesis

Lin-Yu Lu, Jiaxue Wu, L. Ye, G. Gavrilina, T. Saunders, Xiaochun Yu

Developmental Cell

DOI

2009

PTIP Regulates 53BP1 and SMC1 at the DNA Damage Sites*

Jiaxue Wu, Marc J. Prindle, G. Dressler, Xiaochun Yu

Journal of Biological Chemistry

DOI

2009

Integrator3, a Partner of Single-stranded DNA-binding Protein 1, Participates in the DNA Damage Response*

Feng Zhang, Jiaxue Wu, Xiaochun Yu

Journal of Biological Chemistry

DOI

2009

PALB2 Links BRCA1 and BRCA2 in the DNA-Damage Response

Feng Zhang, Jianglin Ma, Jiaxue Wu, L. Ye, Hong Cai, Bing Xia, Xiaochun Yu

Current Biology

DOI

2008

Histone Ubiquitination Associates with BRCA1-Dependent DNA Damage Response

Jiaxue Wu, M. Huen, Lin-Yu Lu, L. Ye, Y. Dou, M. Ljungman, Jun-Jie Chen, Xiaochun Yu

Molecular and Cellular Biology

DOI

2007

CCDC98 targets BRCA1 to DNA damage sites

Zixing Liu, Jiaxue Wu, Xiaochun Yu

Nature Structural &Molecular Biology

DOI

吴家雪

精选作品

期刊论文

p300/CBP-Driven Acetylation Stabilizes PARP7 to Reinforce Negative Feedback on Type I Interferon Signaling

Beauvericin promotes autophagy and mitophagy by activating NIPSNAP2.

Single-cell-based identification of drug synergy with immunotherapy via tumor microenvironment remodeling

PARP15在肺腺癌中的表达及其对肺腺癌细胞生长、凋亡的影响

PARP9促进肺腺癌细胞的迁移和侵袭

Poly(ADP-ribosyl)ation mediates early phase histone eviction at DNA lesions

PARP1调节肝癌细胞的生长和迁移

多聚ADP-核糖结合蛋白的鉴定

RNF168 forms a functional complex with RAD6 during the DNA damage response

CHFR is important for the first wave of ubiquitination at DNA damage sites

RAP80 Protein Is Important for Genomic Stability and Is Required for Stabilizing BRCA1-A Complex at DNA Damage Sites in Vivo*

Chfr and RNF8 synergistically regulate ATM activation

RBX1 (RING Box Protein 1) E3 Ubiquitin Ligase Is Required for Genomic Integrity by Modulating DNA Replication Licensing Proteins*

RNF8-dependent histone modifications regulate nucleosome removal during spermatogenesis

PTIP Regulates 53BP1 and SMC1 at the DNA Damage Sites*

Integrator3, a Partner of Single-stranded DNA-binding Protein 1, Participates in the DNA Damage Response*

PALB2 Links BRCA1 and BRCA2 in the DNA-Damage Response

Histone Ubiquitination Associates with BRCA1-Dependent DNA Damage Response

CCDC98 targets BRCA1 to DNA damage sites

研究方向