周焕焕｜武汉轻工大学｜学者主页

2026

Genome-wide CRISPR screening identifies RAB8B as a candidate target for improving disease resistance against Glaesserella parasuis in pigs

Huanhuan Zhou, Xuexue Chen, Shuilian Li, Jiayi Zeng, Hailong Liu, Xinqi Zeng, Ke Xu, Xiangwei Deng, Xiaoyu Zhang, Shengsong Xie, Hongbo Chen

BMC Veterinary Research

DOI

2026

Transcriptomic Profiling Reveals Candidate lncRNA-S100-GPCR Co-Expression Networks in Lungs of Piglets Infected with Glaesserella parasuis

Jiayi Zeng, Xinqi Zeng, Xiangwei Deng, Shijia Duan, Ke Xu, Huanhuan Zhou, Hongbo Chen

Animals

DOI

2026

Integration of bulk RNA-seq and scRNA-seq reveals cell subsets and gene signatures associated with Glaesserella parasuis infection

Ke Xu, Zixin Wang, Ying Zhu, Z.H. Liu, Min Xiang, Huanhuan Zhou, Ao Zhou, Liu Q, Liangyu Shi, Xiangwei Deng, Xinqi Zeng, Lei Cheng, Hongbo Chen

BMC Genomics

DOI

2026

TEAD4 Promotes Myogenic Differentiation of Porcine Skeletal Muscle Satellite Cells

Huanhuan Zhou, Jiayi Zeng, Xiaoyu Zhang, Xinqi Zeng, Ke Xu, Hongbo Chen

Animals

DOI

2026

ST6GALNAC5 promotes Glaesserella parasuis infection by enhancing bacterial adhesion and amplifying host inflammatory responses

Huanhuan Zhou, Xuexue Chen, Jiayi Zeng, Shijia Duan, Hailong Liu, Xinqi Zeng, Xiaoyu Zhang, Ke Xu, Shengsong Xie, Hongbo Chen

Veterinary Microbiology

DOI

2025

基于80K SNP芯片的梅花星猪群体遗传结构解析及全基因组连续纯合片段特征研究

刘莎，杨彩春，张晓雨，陈琼，刘雄，陈洪波，周焕焕，史良玉

《畜牧兽医学报》

2025

Genome-wide adaptive selection and functional annotation of regulatory variation in the Yangxin pig

Sha Liu, Qiong Chen, Huanhuan Zhou, Caichun Yang, Liangyu Shi, Hongbo Chen

BMC Genomics

DOI

2025

A novel function of RHOA as a host-dependent factor in Glaesserella parasuis infection of LLC-PK1 cells

Huanhuan Zhou, Xuexue Chen, Xinqi Zeng, Shengsong Xie, Xiaoyu Zhang, Jiayi Zeng, Ke Xu, Bo Yu, Hailong Liu, Hongbo Chen

Veterinary Research

DOI

2024

呕吐毒素体外刺激3D4/21猪肺泡巨噬细胞对炎性因子和m6A甲基化相关基因表达的影响

丰伟丽，薛智慧，赵庆博，周焕焕，周傲，刘玉兰，张晶

《中国畜牧杂志》

2024

Transcriptome Analysis Reveals Novel Inflammatory Signalings to Glaesserella parasuis Infection

Jingwen Lei, Xuexue Chen, Huanhuan Zhou, Zekai Zhang, Zhong Xu, Ke Xu, Hongbo Chen

Genes

DOI

2024

Transcriptome Analysis of miRNA and mRNA in Porcine Skeletal Muscle following Glaesserella parasuis Challenge

Huanhuan Zhou, Xuexue Chen, Xiangwei Deng, Xiaoyu Zhang, Xinqi Zeng, Ke Xu, Hongbo Chen

Genes

DOI

2023

基于转录组测序探究地塞米松在前体脂肪细胞成脂分化过程中的作用机制

杨涛，周佳伟，张宇，徐忠，吴俊静，乔木，冯越，李梓芃，彭先文，周焕焕，陈洪波，徐珂，梅书棋

《中国畜牧杂志》

2023

PLIN2调控宁乡猪原代肾成纤维细胞ω-3 PUFA组成的研究

李志敏，方钱海，王锐，陈洪波，周焕焕，张立苹

《中国畜牧杂志》

2023

Integrated Analysis of Long Non-Coding RNA Expression Profiles in Glaesserella parasuis-Induced Meningitis: New Insight into Pathogenesis

Peiyan Sun, Yaqiong Yang, Hongxin Chen, Shulin Fu, Yulan Liu, Yinsheng Qiu, Hongbo Chen, Jing Zhang, Huanhuan Zhou, Liangyu Shi, Hongyan Ren, Zhe Chao, Ling Guo

Microbiology Research

DOI

2023

Correction: Deng et al. Assessment of the Macrophage Scavenger Receptor CD163 in Mediating Glaesserella parasuis Infection of Host Cells. Vet. Sci. 2023, 10, 235

Xiangwei Deng, Shuilian Li, Ying Jie Zhu, Bo Yu, Jing Zhang, Qianhai Fang, Zhimin Li, Hongbo Chen, Huanhuan Zhou

Veterinary Sciences

DOI

2023

Assessment of the Macrophage Scavenger Receptor CD163 in Mediating Glaesserella parasuis Infection of Host Cells

Xiangwei Deng, Shuilian Li, Ying Jie Zhu, Bo Yu, Jing Zhang, Qianhai Fang, Zhimin Li, Hongbo Chen, Huanhuan Zhou

Veterinary Sciences

DOI

2022

副猪嗜血杆菌体外刺激3D4/21猪肺泡巨噬细胞对炎性因子和m6A相关基因表达的影响

薛智慧，郭鑫，李水莲，周焕焕，陈洪波，任红艳，张晶

《黑龙江畜牧兽医》

2022

副猪嗜血杆菌感染禁食初乳CD仔猪模型及感染相关表型组构建

刘正芳，朱颖，张烁，刘青，张晶，周焕焕，周傲，史良玉，陈洪波

《中国畜牧杂志》

2021

猪CD163瞬时转染CHO-K1超表达细胞模型的构建及鉴定

王柳，张泽锴，周焕焕，周傲，张晶，陈洪波

《武汉轻工大学学报》

2020

MicroRNA调控元件鉴定及调控成肌细胞分化的功能研究

周焕焕

《华中农业大学》

2019

猪骨骼肌发育过程中免疫相关基因的表达分析

胡明阳，周焕焕，齐晓龙，许月园，赵书红，赵云霞，李新云

《中国畜牧杂志》

DOI

周焕焕

精选作品

期刊论文

Genome-wide CRISPR screening identifies RAB8B as a candidate target for improving disease resistance against Glaesserella parasuis in pigs

Transcriptomic Profiling Reveals Candidate lncRNA-S100-GPCR Co-Expression Networks in Lungs of Piglets Infected with Glaesserella parasuis

Integration of bulk RNA-seq and scRNA-seq reveals cell subsets and gene signatures associated with Glaesserella parasuis infection

TEAD4 Promotes Myogenic Differentiation of Porcine Skeletal Muscle Satellite Cells

ST6GALNAC5 promotes Glaesserella parasuis infection by enhancing bacterial adhesion and amplifying host inflammatory responses

基于80K SNP芯片的梅花星猪群体遗传结构解析及全基因组连续纯合片段特征研究

Genome-wide adaptive selection and functional annotation of regulatory variation in the Yangxin pig

A novel function of RHOA as a host-dependent factor in Glaesserella parasuis infection of LLC-PK1 cells

呕吐毒素体外刺激3D4/21猪肺泡巨噬细胞对炎性因子和m6A甲基化相关基因表达的影响

Transcriptome Analysis Reveals Novel Inflammatory Signalings to Glaesserella parasuis Infection

Transcriptome Analysis of miRNA and mRNA in Porcine Skeletal Muscle following Glaesserella parasuis Challenge

基于转录组测序探究地塞米松在前体脂肪细胞成脂分化过程中的作用机制

PLIN2调控宁乡猪原代肾成纤维细胞ω-3 PUFA组成的研究

Integrated Analysis of Long Non-Coding RNA Expression Profiles in Glaesserella parasuis-Induced Meningitis: New Insight into Pathogenesis

Correction: Deng et al. Assessment of the Macrophage Scavenger Receptor CD163 in Mediating Glaesserella parasuis Infection of Host Cells. Vet. Sci. 2023, 10, 235

Assessment of the Macrophage Scavenger Receptor CD163 in Mediating Glaesserella parasuis Infection of Host Cells

副猪嗜血杆菌体外刺激3D4/21猪肺泡巨噬细胞对炎性因子和m6A相关基因表达的影响

副猪嗜血杆菌感染禁食初乳CD仔猪模型及感染相关表型组构建

猪CD163瞬时转染CHO-K1超表达细胞模型的构建及鉴定

MicroRNA调控元件鉴定及调控成肌细胞分化的功能研究

猪骨骼肌发育过程中免疫相关基因的表达分析

会议论文

基于全基因组关联分析鉴定阳新猪肋骨数相关结构变异

猪RAB8B通过TLR5/NF-κB信号介导副猪嗜血杆菌感染宿主细胞的分子机制

猪肺泡巨噬细胞响应副猪嗜血杆菌感染的关键亚群鉴定及分子机制

研究方向