熊晶

2026

脂毒性驱动代谢相关脂肪性肝病/代谢功能障碍相关脂肪性肝炎进展的机制及相关新药研究进展

《药学进展》

DOI

2026

溶质载体家族肝脏细胞表达特征及其在药物性肝损伤中的分子机制与靶向策略

《中国药科大学学报》

2026

SLC13A2-transported citrate remodels transcriptional regulation through protein acetylation to suppress tumor growth

Science Advances

DOI

2026

Technology-enabled insights into SLC transporters in MAFLD: redefining the multi-hit pathogenesis and therapeutic landscape

Acta Pharmacologica Sinica

DOI

2025

Case Report: Clinical features and management of anti-mGluR1 encephalitis: case illustration and review of the literature

Frontiers In Integrative Neuroscience，Vol. 19

DOI

2025

癌基因驱动的肝癌代谢重编程及潜在用药策略

《药学进展》

DOI

2024

辅助性评价在形成性评价中的应用策略——以药学本科教育为例

《药学研究》

2023

Endothelial Brg1 fine-tunes Notch signaling during zebrafish heart regeneration

npj Regenerative Medicine

DOI

2022

Phosphorylation-Induced Ubiquitination and Degradation of PXR through CDK2-TRIM21 Axis

Cells

DOI

2022

Single-cell analysis reveals an Angpt4-initiated EPDC-EC-CM cellular coordination cascade during heart regeneration

Protein & Cell

DOI

2022

A small-molecule cocktail promotes mammalian cardiomyocyte proliferation and heart regeneration.

Cell Stem Cell

DOI

2022

Dusp6 deficiency attenuates neutrophil-mediated cardiac damage in the acute inflammatory phase of myocardial infarction

Nature Communications

DOI

2021

Corrigendum: Inhibition of TGF-β/Smad3 Signaling Disrupts Cardiomyocyte Cell Cycle Progression and Epithelial–Mesenchymal Transition-Like Response During Ventricle Regeneration

Frontiers in Cell and Developmental Biology

DOI

2021

Molecular regulation of myocardial proliferation and regeneration

Cell Regeneration

DOI

2021

Diverse biological and engineering strategies towards organ regeneration

Cell Regeneration

DOI

2021

BMP and Notch Signaling Pathways differentially regulate Cardiomyocyte Proliferation during Ventricle Regeneration

International Journal on Biological Sciences

DOI

2021

Inhibition of TGF-β/Smad3 Signaling Disrupts Cardiomyocyte Cell Cycle Progression and Epithelial–Mesenchymal Transition-Like Response During Ventricle Regeneration

Frontiers in Cell and Developmental Biology

DOI

2020

Evolutionary insights into heart regeneration

Cell Regeneration

DOI

2020

Critical role of zebrafish dnajb5 in myocardial proliferation and regeneration.

Journal of genetics and genomics = Yi chuan xue bao

DOI

2020

p53 isoform Δ113p53 promotes zebrafish heart regeneration by maintaining redox homeostasis

Cell Death and Disease

DOI

2020

Light-sheet fluorescence imaging charts the gastrula origin of vascular endothelial cells in early zebrafish embryos

bioRxiv

DOI

2019

Insulin transcriptionally down-regulates carboxylesterases through pregnane X receptor in an Akt-dependent manner.

Toxicology

DOI

2019

In vivo imaging of β-cell function reveals glucose-mediated heterogeneity of β-cell functional development

eLife

DOI

2019

Systematic genome editing of the genes on zebrafish Chromosome 1 by CRISPR/Cas9

Genome Research

DOI

2019

Nanoparticle-mediated delivery of siRNA into zebrafish heart: a cell-level investigation on the biodistribution and gene silencing effects.

Nanoscale

DOI

2018

17&bgr;‐estradiol suppresses carboxylesterases by activating c‐Jun/AP‐1 pathway in primary human and mouse hepatocytes

European Journal of Pharmacology

DOI

2018

Fluoxetine induces lipid metabolism abnormalities by acting on the liver in patients and mice with depression

Acta Pharmacologica Sinica

DOI

2018

Nanoparticle-mediated siRNA Gene-silencing in Adult Zebrafish Heart.

Journal of Visualized Experiments

DOI

2018

Author response: In vivo imaging of β-cell function reveals glucose-mediated heterogeneity of β-cell functional development

DOI

2018

Epigenetic Regulation of Organ Regeneration in Zebrafish

Journal of Cardiovascular Development and Disease

DOI

2017

Suppression of carboxylesterases by imatinib mediated by the down‐regulation of pregnane X receptor

British Journal of Pharmacology

DOI

2017

Downregulation of DEC1 contributes to the neurotoxicity induced by MPP+ by suppressing PI3K/Akt/GSK3β pathway

CNS Neuroscience & Therapeutics

DOI

2017

Involvement of pregnane X receptor in the suppression of carboxylesterases by metformin in vivo and in vitro, mediated by the activation of AMPK and JNK signaling pathway

European Journal of Pharmaceutical Sciences

DOI

2017

A novel inducible mutagenesis screen enables to isolate and clone both embryonic and adult zebrafish mutants

Scientific Reports

DOI

2017

In vivo Imaging β-cell Function Reveals Two Waves of β-cell Maturation

bioRxiv

DOI

2017

Toxicity of chlordane at early developmental stage of zebrafish

bioRxiv

DOI

2016

Serum high-sensitivity C-reactive protein: A delicate sentinel elevated in drug-free acutely agitated patients with schizophrenia

Psychiatry Research，Vol. 246

DOI

2016

Aspafilioside B induces G2/M cell cycle arrest and apoptosis by up‐regulating H‐Ras and N‐Ras via ERK and p38 MAPK signaling pathways in human hepatoma HepG2 cells

Molecular Carcinogenesis

DOI

2016

Fluoxetine reduces CES1, CES2, and CYP3A4 expression through decreasing PXR and increasing DEC1 in HepG2 cells

Xenobiotica; the fate of foreign compounds in biological systems

DOI

2016

The anti-metastatic effect of 8-MOP on hepatocellular carcinoma is potentiated by the down-regulation of bHLH transcription factor DEC1.

Pharmacological Research

DOI

2016

Chromatin-remodelling factor Brg1 regulates myocardial proliferation and regeneration in zebrafish

Nature Communications

DOI

2016

Erratum to: Questions about NgAgo

Protein & Cell

DOI

2016

Spliceosomal protein eftud2 mutation leads to p53-dependent apoptosis in zebrafish neural progenitors

Nucleic Acids Research

DOI

2016

Questions about NgAgo

Protein & Cell

DOI

2016

A Neutralized Noncharged Polyethylenimine-Based System for Efficient Delivery of siRNA into Heart without Toxicity.

ACS Applied Materials and Interfaces

DOI

2016

Nanoparticle-based nonviral delivery of siRNA in zebrafish heart: gene silencing efficiency and siRNA biodistribution

DOI

2015

Stimulation of nitric oxide production contributes to the antiplatelet and antithrombotic effect of new peptide pENW (pGlu-Asn-Trp).

Thrombosis Research

DOI

2015

Decreased carboxylesterases expression and hydrolytic activity in type 2 diabetic mice through Akt/mTOR/HIF-1α/Stra13 pathway

Xenobiotica; the fate of foreign compounds in biological systems

DOI

2015

Composition for activating cardiac regeneration and application of composition

2015

Mecp2 regulates neural cell differentiation by suppressing the Id1 to Her2 axis in zebrafish

Journal of Cell Science

DOI

2015

Antimalarial drug artemisinin depletes erythrocytes by activating apoptotic pathways in zebrafish.

Experimental Hematology

DOI

2015

JCS suppl info

2015

PEG-PLA nanoparticles facilitate siRNA knockdown in adult zebrafish heart.

Developmental Biology

DOI

2015

Talin1 is required for cardiac Z‐disk stabilization and endothelial integrity in zebrafish

The FASEB Journal

DOI

2015

Remodeling of Mitochondrial Flashes in Muscular Development and Dystrophy in Zebrafish

PLoS ONE

DOI

2014

Hydrogen peroxide primes heart regeneration with a derepression mechanism

Cell Research

DOI

2014

Heritable/conditional genome editing in C. elegans using a CRISPR-Cas9 feeding system

Cell Research

DOI

2014

Fluoxetine suppresses AMP-activated protein kinase signaling pathway to promote hepatic lipid accumulation in primary mouse hepatocytes.

International Journal of Biochemistry and Cell Biology

DOI

2014

Glucose dominates the regulation of carboxylesterases induced by lipopolysaccharide or interleukin-6 in primary mouse hepatocytes.

Life Science

DOI

2014

Haploinsufficiency of Def Activates p53-Dependent TGFβ Signalling and Causes Scar Formation after Partial Hepatectomy

PLoS ONE

DOI

2014

Protein tyrosine phosphatase PTPN9 regulates erythroid cell development through STAT3 dephosphorylation in zebrafish

Journal of Cell Science

DOI

2014

PTPN 9 in erythroid development 2

2013

灵仙新苷对高脂血症大鼠早期动脉粥样硬化的干预作用

《中国新药杂志》

2013

有的放矢,因材施教——医学留学生药理学教学新模式的探索与实践

《南京医科大学学报(社会科学版)》

2013

Genome editing with RNA-guided Cas9 nuclease in Zebrafish embryos

Cell Research

DOI

2013

Heritable gene-targeting with gRNA/Cas9 in rats

Cell Research

DOI

2013

Curcumin Protects against 1-Methyl-4-phenylpyridinium Ion- and Lipopolysaccharide-Induced Cytotoxicities in the Mouse Mesencephalic Astrocyte via Inhibiting the Cytochrome P450 2E1

Evidence-Based Complementary and Alternative Medicine

DOI

2013

Genetic interaction between pku300 and fbn2b controls endocardial cell proliferation and valve development in zebrafish

Journal of Cell Science

DOI

2013

Recent advances in heart regeneration.

Birth Defects Research Part C Embryo Today Reviews

DOI

2012

Fluoxetine Induces Hepatic Lipid Accumulation Via Both Promotion of the SREBP1c‐Related Lipogenesis and Reduction of Lipolysis in Primary Mouse Hepatocytes

CNS Neuroscience & Therapeutics

DOI

2012

Down regulation of differentiated embryonic chondrocytes 1 (DEC1) is involved in 8-methoxypsoralen-induced apoptosis in HepG2 cells.

Toxicology

DOI

2012

DEC1 binding to the proximal promoter of CYP3A4 ascribes to the downregulation of CYP3A4 expression by IL-6 in primary human hepatocytes

Biochemical Pharmacology

DOI

2012

New peptide pENW (pGlu-Asn-Trp) inhibits platelet activation by attenuating Akt phosphorylation.

European Journal of Pharmaceutical Sciences

DOI

2012

[Vascular endothelial cell development and underlying mechanisms].

Yi chuan = Hereditas

2012

Overlapping cardiac programs in heart development and regeneration.

Journal of genetics and genomics = Yi chuan xue bao

DOI

2011

[Recent progress in heart regeneration].

Yi chuan = Hereditas

DOI

2011

Rad GTPase inhibits cardiac fibrosis through connective tissue growth factor.

Cardiovascular Research

DOI

2011

Platelet-Derived Growth Factor Induces Rad Expression through Egr-1 in Vascular Smooth Muscle Cells

PLoS ONE

DOI

2010

整合素受体与血小板活化及其药物研究进展

《中国新药杂志》

2008

Molecular and developmental biology of the hemangioblast

Developmental Dynamics

DOI

2008

An Acyltransferase Controls the Generation of Hematopoietic and Endothelial Lineages in Zebrafish

Circulation Research

DOI

2007

Mouse lysocardiolipin acyltransferase controls the development of hematopoietic and endothelial lineages during in vitro embryonic stem-cell differentiation.

Blood

DOI

2007

BMPER is a conserved regulator of hematopoietic and vascular development in zebrafish.

Journal of Molecular and Cellular Cardiology

DOI

2007

Abstract 430: An Acyltransferase Controls The Generation Of Hematopoietic And Endothelial Lineages In Zebrafish And Mouse ES Cells

2006

The transcription factor ZBP-89 controls generation of the hematopoietic lineage in zebrafish and mouse embryonic stem cells

Development

DOI

2005

Dosage-dependent requirement for mouse Vezf1 in vascular system development.

Developmental Biology

DOI

2003

肿瘤化疗过程中3种止吐药物应用的成本—效果分析

《华西药学杂志》

1999

Vezf1: A Zn finger transcription factor restricted to endothelial cells and their precursors.

Developmental Biology

DOI

1999

Use of developmental marker genes to define temporal and spatial patterns of differentiation during embryoid body formation.

The Journal of experimental zoology

DOI

1999

Retroviral promoter-trap insertion into a novel mammalian septin gene expressed during mouse neuronal development.

Mechanisms of Development

DOI

1998

Large‐scale screening for developmental genes in embryonic stem cells and embryoid bodies using retroviral entrapment vectors

Developmental Dynamics

DOI