李鸿珠｜厦门大学｜学者主页

期刊论文

2026

Hydrogen sulfide promotes S-sulfhydration of TrxR1 and attenuates diabetic vascular remodeling

Ziyi Wei, Ren Wu, Jiawen Ruan, Jiahe Yang, Xinxin Fu, Yashi Li, Lijie Jiao, 相里飞, Dan Yu, Guoliang Yan, Lili Zhang, Hongzhu Li

Cell Death Discovery

DOI

2025

Hydrogen sulfide alleviates vascular smooth muscle cell senescence by inhibiting endoplasmic reticulum stress.

Lijie Jiao, Qiuyi Yan, Jiahe Yang, Ren Wu, Ziyi Wei, Jia-Ling Ruan, Guoliang Yan, Xu Chen, Hongzhu Li

Cellular Signalling

DOI

2024

外源性硫化氢对肾小球系膜细胞缺氧/复氧损伤的影响及其机制

林真亭，田华，李鸿珠

《中国药理学通报》

2024

Hydrogen sulfide inhibits skeletal muscle ageing by up‐regulating autophagy through promoting deubiquitination of adenosine 5’‐monophosphate (AMP)‐activated protein kinase α1 via ubiquitin specific peptidase 5

Jiahe Yang, Jun Gao, Y. E, Lijie Jiao, Ren Wu, Qiuyi Yan, Ziyi Wei, Guoliang Yan, Jingjing Liang, Hongzhu Li

Journal of Cachexia, Sarcopenia and Muscle

DOI

2023

硫化氢抗衰老作用的分子机制

武韧，李鸿珠

《中国生物化学与分子生物学报》

2023

Exogenous H2S alleviates senescence of glomerular mesangial cells through up-regulating mitophagy by activation of AMPK-ULK1-PINK1-parkin pathway in mice

E Ya‐Qi, Yan Lin, Guoliang Yan, Jiahe Yang, Lijie Jiao, Ren Wu, Qiuyi Yan, Yinuo Chen, Yong-Xiang Chen, Xinwu Yan, Hongzhu Li

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

DOI

2022

Deficiency of cystathionine gamma-lyase promotes aortic elastolysis and medial degeneration in aged mice

Jiechun Zhu, Yuehong Wang, Alexis Rivett, Hongzhu Li, Lingyun Wu, Rui Wang, Rui Wang

Journal of Molecular and Cellular Cardiology

DOI

2022

DR1-CSE/H 2 S pathway upregulates autophagy and inhibits H9C2 cells damage induced by high glucose

Hongzhu Li, Yaxin Wei, Yuxin Xi, Lijie Jiao, Xin Wen, Ren Wu, Guiquan Chang, Fengqi Sun, Jinghui Hao

Acta cardiologica. Supplementum

DOI

2022

Dopamine 1 receptors inhibit apoptosis via activating CSE/H2S pathway in high glucose‐induced vascular endothelial cells

Hongzhu Li, Hongzhu Li, Ren Wu, Yuxin Xi, Hongxia Li, Hongxia Li, Guiquan Chang, Fengqi Sun, Can Wei, Lijie Jiao, Xin Wen, Gensheng Zhang, Zaid Altaany, Jinghui Hao

Cell Biology International

DOI

2022

Exogenous hydrogen sulfide inhibits the senescence of cardiomyocytes through modulating mitophagy in rats

Jinghui Hao, Yuxin Xi, Lijie Jiao, Xin Wen, Ren Wu, Guiquan Chang, Fengqi Sun, Can Wei, Hongzhu Li

Cellular Signalling

DOI

2022

SKF38393 prevents high glucose (HG)-induced endothelial dysfunction by inhibiting the effects of HG on cystathionine γ-lyase/hydrogen sulfide activity and via a RhoA/ROCK1 pathway

Guiquan Chang, Shuzhi Bai, Fengqi Sun, Ren Wu, Can Wei, Xin Wen, Yuxin Xi, Jinghui Hao, Zaid Altaany, Hongzhu Li

Frontiers in Bioscience-Landmark

DOI

2022

DR1 Activation Inhibits the Proliferation of Vascular Smooth Muscle Cells through Increasing Endogenous H 2 S in Diabetes

Yuxin Xi, Xin Wen, Yuanzhou Zhang, Lijie Jiao, Shuzhi Bai, Sa Shi, Guiquan Chang, Ren Wu, Fengqi Sun, Jinghui Hao, Hongzhu Li

Aging and Disease

DOI

2021

硫化氢通过抑制氧化应激减轻糖尿病心肌病病变

矫立杰，魏亚新，李鸿珠

《基础医学与临床》

2021

硫化氢对糖尿病心肌病的保护作用

武韧，常贵全，孙凤起，李鸿珠

《心血管病学进展》

DOI

2021

The DR1‑CSE/H2S system inhibits renal fibrosis by downregulating the ERK1/2 signaling pathway in diabetic mice

Hongzhu Li, Fengqi Sun, Shuzhi Bai, Guiquan Chang, Ren Wu, Yaxin Wei, Xin Wen, Yuxin Xi, Jinghui Hao, Zaid Altaany

International Journal of Molecular Medicine

DOI

2020

硫化氢在细胞自噬中的作用及机制

魏亚新，矫立杰，李鸿珠

《医学研究杂志》

2020

外源性H2S对糖尿病小鼠肝纤维化的作用及其机制

席雨鑫，温馨，矫立杰，魏亚新，常贵全，武韧，孙凤起，郝静辉，李鸿珠

《中国应用生理学杂志》

2020

硫化氢在糖尿病血管内皮细胞功能障碍中的作用及机制

常贵全，武韧，李鸿珠

《中国生物化学与分子生物学报》

DOI

2019

硫化氢对衰老缺血心肌细胞保护作用的研究进展

张源洲，席雨鑫，温馨，李鸿珠

《基础医学与临床》

2018

外源性H2S恢复缺氧后适应对衰老H9C2细胞的保护作用及机制

孙伟铭，张源洲，温馨，席雨鑫，袁迪，王跃虹，魏璨，徐长庆，李鸿珠

《中国应用生理学杂志》

2016

外源性H2S恢复老龄大鼠心肌缺血后适应对I/R损伤的缓解作用

李丽娜，孙伟铭，高君，王跃虹，魏璨，徐长庆，李鸿珠

《基础医学与临床》

2015

CSE/H2S通路缺失影响小鼠肝脏胆固醇和脂肪酸代谢（英文）

Sarathi Mani, Hongzhu Li, Guangdong Yang, Lingyun Wu, Rui Wang

Science Bulletin

会议论文

2017

外源性硫化氢(H2S)恢复缺血后适应对老龄大鼠心肌保护作用的机制研究

李鸿珠

《第十一届海峡两岸心血管科学研讨会、2017年全国心脑血管药理学术会议、中国卒中学会第一次新药研讨会论文集》

DOI

李鸿珠

精选作品

期刊论文

Hydrogen sulfide promotes S-sulfhydration of TrxR1 and attenuates diabetic vascular remodeling

Hydrogen sulfide alleviates vascular smooth muscle cell senescence by inhibiting endoplasmic reticulum stress.

外源性硫化氢对肾小球系膜细胞缺氧/复氧损伤的影响及其机制

Hydrogen sulfide inhibits skeletal muscle ageing by up‐regulating autophagy through promoting deubiquitination of adenosine 5’‐monophosphate (AMP)‐activated protein kinase α1 via ubiquitin specific peptidase 5

硫化氢抗衰老作用的分子机制

Exogenous H2S alleviates senescence of glomerular mesangial cells through up-regulating mitophagy by activation of AMPK-ULK1-PINK1-parkin pathway in mice

Deficiency of cystathionine gamma-lyase promotes aortic elastolysis and medial degeneration in aged mice

DR1-CSE/H 2 S pathway upregulates autophagy and inhibits H9C2 cells damage induced by high glucose

Dopamine 1 receptors inhibit apoptosis via activating CSE/H2S pathway in high glucose‐induced vascular endothelial cells

Exogenous hydrogen sulfide inhibits the senescence of cardiomyocytes through modulating mitophagy in rats

SKF38393 prevents high glucose (HG)-induced endothelial dysfunction by inhibiting the effects of HG on cystathionine γ-lyase/hydrogen sulfide activity and via a RhoA/ROCK1 pathway

DR1 Activation Inhibits the Proliferation of Vascular Smooth Muscle Cells through Increasing Endogenous H 2 S in Diabetes

硫化氢通过抑制氧化应激减轻糖尿病心肌病病变

硫化氢对糖尿病心肌病的保护作用

The DR1‑CSE/H2S system inhibits renal fibrosis by downregulating the ERK1/2 signaling pathway in diabetic mice

硫化氢在细胞自噬中的作用及机制

外源性H2S对糖尿病小鼠肝纤维化的作用及其机制

硫化氢在糖尿病血管内皮细胞功能障碍中的作用及机制

硫化氢对衰老缺血心肌细胞保护作用的研究进展

外源性H2S恢复缺氧后适应对衰老H9C2细胞的保护作用及机制

外源性H2S恢复老龄大鼠心肌缺血后适应对I/R损伤的缓解作用

CSE/H2S通路缺失影响小鼠肝脏胆固醇和脂肪酸代谢（英文）

会议论文

外源性硫化氢(H2S)恢复缺血后适应对老龄大鼠心肌保护作用的机制研究

研究方向