陈笛｜重庆医科大学｜学者主页

2026

重复经颅磁刺激联合丁苯酞治疗帕金森病患者的效果观察

邢检，顾亮亮，丁彦博，陈笛，乔鑫，李娟，周国平

《临床医学工程》

2026

复方苁蓉益智胶囊联合银杏叶提取物对VCIND患者认知功能和血清BDNF、MMP-9水平影响的研究

王岩，张玉凤，陈笛，邢检，李翀，顾亮亮

《中国民族医药杂志》

DOI

2026

MCA急性脑梗死患者药物溶栓治疗的预后影响因素分析

张玉凤，顾亮亮，陈笛，王岩，乔鑫，李娟，柴长彪

《临床荟萃》

2026

免疫球蛋白联合甲泼尼龙治疗自身免疫性脑炎的效果观察

李翀，陈笛，孔一帆，邢娟，温昌明，顾亮亮

《淮海医药》

DOI

2025

高压氧联合醒脑静注射液及艾地苯醌片治疗血管性痴呆的疗效及对患者脑血流状态、氧化应激反应的影响

张玉凤，顾亮亮，王岩，陈笛，邢检，李翀

《深圳中西医结合杂志》

DOI

2025

Behavioral Abnormalities, Cognitive Impairments, Synaptic Deficits, and Gene Replacement Therapy in a CRISPR Engineered Rat Model of 5p15.2 Deletion Associated With Cri du Chat Syndrome

Jingjing Shen, Yan Wang, Yan Wang, Yang Liu, Junying Lan, Shuang Long, Yingbo Li, Di Chen, Peng Yu, Jing Zhao, Yongjun Wang, Yongjun Wang, Shali Wang, Feng Yang

Advanced Science

DOI

2024

橘皮素调控PI3K/Akt信号通路介导的自噬对脑缺血/再灌注损伤大鼠神经细胞焦亡的影响

孙军，温昌明，张丽阳，高军，张在行，陈笛，时彩丽，兰端云，张保朝

《中国药学杂志》

2024

早期康复护理对NMOSD患者症状评分、生活活动能力的影响

孔一帆，顾亮亮，丁彦博，陈笛，李娟，邢检，李翀，张玉凤

《齐鲁护理杂志》

2024

日常饮食中添加摄食甜菜碱对APP/PS1转基因小鼠的影响

张丽阳，孙军，陈笛，张在行

《中成药》

2023

Melatonin ameliorates sleep-wake disturbances and autism-like behaviors in the Ctnnd2 knock out mouse model of autism spectrum disorders

Man Xu, Luyi Wang, Yan Wang, Jing Deng, Xiaoya Wang, Feifei Wang, Sen Pan, Yu Zhao, Ailing Liao, Xiaoqing Wang, Di Chen, Jingjing Shen, Feng Yang, Yingbo Li, Shali Wang

Genes Brain And Behavior，Vol. 22, No. 40

DOI

2023

Associations of DNA Methylation With Behavioral Problems, Gray Matter Volumes, and Negative Life Events Across Adolescence: Evidence From the Longitudinal IMAGEN Study

Yan Sun, Tianye Jia, Edward D. Barker, Di Chen, Zuo Zhang, Jiayuan Xu, Suhua Chang, Guangdong Zhou, Yun Liu, Nicole Tay, Qiang Luo, Xiao Chang, Tobias Banaschewski, Arun L. W. Bokde, Herta Flor, Antoine Grigis, Hugh Garavan, Andreas Heinz, Jean-Luc Martinot, Marie-Laure Paillere Martinot, Eric Artiges, Frauke Nees, Dimitri Papadopoulos Orfanos, Tomas Paus, Luise Poustka, Sarah Hohmann, Sabina Millenet, Juliane H. Froehner, Michael N. Smolka, Henrik Walter, Robert Whelan, Lin Lu, Jie Shi, Gunter Schumann, Sylvane Desrivieres

Biological Psychiatry，Vol. 93, No. 4

DOI

2023

miR-124通过抑制TLR4/NF-κB/CCL2对脑梗死大鼠神经元凋亡的影响

陈笛，温昌明，李祥欣，孙军，高军，张在行，张东焕，张保朝

《中国老年学杂志》

2023

支架取栓术联合替罗非班及丁苯酞治疗急性脑梗死的效果

孙军，张丽阳，陈笛，温昌明，时彩丽，兰端云

《郑州大学学报(医学版)》

2023

老年腔隙性脑梗死合并高血压患者认知功能障碍影响因素分析及25-羟基维生素D的预测价值

陈笛，顾亮亮，孙军，高军，张东焕，温昌明，张保朝

《临床心身疾病杂志》

2022

Brain Signatures During Reward Anticipation Predict Persistent Attention-Deficit/Hyperactivity Disorder Symptoms

Di Chen, Tianye Jia, Wei Cheng, Miao Cao, Tobias Banaschewski, Gareth J. Barker, Arun L. W. Bokde, Uli Bromberg, Christian Buchel, Sylvane Desrivieres, Herta Flor, Antoine Grigis, Hugh Garavan, Penny A. Gowland, Andreas Heinz, Bernd Ittermann, Jean-Luc Martinot, Marie-Laure Paillere Martinot, Frauke Nees, Dimitri Papadopoulos Orfanos, Tomas Paus, Luise Poustka, Juliane H. Frohner, Michael N. Smolka, Henrik Walter, Robert Whelan, T. W. Robbins, Barbara J. Sahakian, Gunter Schumann, Jianfeng Feng

Journal Of The American Academy Of Child And Adolescent Psychiatry，Vol. 61, No. 8

DOI

2022

Progranulin improves neural development via the PI3K/Akt/GSK-3β pathway in the cerebellum of a VPA-induced rat model of ASD

Lili Wang, Jianhui Chen, Yuling Hu, Ailing Liao, Wenxia Zheng, Xiaoqing Wang, Junying Lan, Jingjing Shen, Shali Wang, Feng Yang, Yan Wang, Yingbo Li, Di Chen

Translational Psychiatry，Vol. 12, No. 10

DOI

2021

Neural Biomarkers Distinguish Severe From Mild Autism Spectrum Disorder Among High-Functioning Individuals

Di Chen, Tianye Jia, Yuning Zhang, Miao Cao, Eva Loth, Chun-Yi Zac Lo, Wei Cheng, Zhaowen Liu, Weikang Gong, Barbara Jacquelyn Sahakian, Jianfeng Feng

Frontiers In Human Neuroscience，Vol. 15

DOI

2021

Abnormal spatiotemporal expression pattern of progranulin and neurodevelopment impairment in VPA-induced ASD rat model

Junying Lan, Yuling Hu, Xiaoqing Wang, Wenxia Zheng, Ailing Liao, Shali Wang, Yingbo Li, Yan Wang, Feng Yang, Di Chen

Neuropharmacology

DOI

2020

藁本内酯对大鼠蛛网膜下腔出血后迟发性血管痉挛的影响

汪小青，竹梅，李英博，陈笛

《神经解剖学杂志》

DOI

2019

δ-联蛋白通过AKT信号通路调控OGD/R后的炎症反应

杜剑秋，李英博，陈笛，王莎莉

《中国生物化学与分子生物学报》

DOI

2019

[Improvement of a mouse model of valproic acid-induced autism].

Wenxia Zheng, Yuling Hu, Di Chen, Yingbo Li, Shali Wang

PubMed

DOI

2019

Male-Specific Conditioned Pain Hypersensitivity in Mice and Humans.

L. J. Martin, E. Acland, Chulmin Cho, W. Gandhi, Di Chen, Elizabeth Corley, Basil Kadoura, T. Levy, Sara Mirali, Sarasa Tohyama, Sana Khan, L. Macintyre, E. Carlson, P. Schweinhardt, J. Mogil

Current Biology

DOI

2018

4-苯基丁酸钠通过抑制内质网应激减轻皮层神经元氧糖剥夺/再灌注损伤

谭婷，王岩，涂柳，陈笛

《中国生物化学与分子生物学报》

2018

Protective Effects of Notoginsenoside R1 via Regulation of the PI3K-Akt-mTOR/JNK Pathway in Neonatal Cerebral Hypoxic–Ischemic Brain Injury

Liu Tu, Yan Wang, Di Chen, Ping Xiang, Jingjing Shen, Yingbo Li, Shali Wang

Neurochemical Research

DOI

2018

A Developmental Study of Abnormal Behaviors and Altered GABAergic Signaling in the VPA-Treated Rat Model of Autism

Qian-Ling Hou, Yan Wang, Yingbo Li, Di Chen, Feng Yang, Shali Wang

Frontiers in Behavioral Neuroscience

DOI

2016

Protective effects of transient receptor potential canonical channels on oxygen–glucose deprivation-induced cell injury in neurons and PC12 cells

Yan Wang, Yingbo Li, Di Chen, Liu Tu, Qianlin Hou, Shali Wang

Neuroreport

DOI

2015

大鼠蛛网膜下腔出血致脑血管痉挛模型的建立

李英博，竹梅，陈笛，王莎莉

《重庆医科大学学报》

2015

(345) Male-specific conditioned pain hypersensitivity in mice and humans

Loren J. Martin, E. Acland, Di Chen, Basil Kadoura, S. Mirali, E. Corley, Sarasa Tohyama, W. Gandhi, P. Schweinhardt, J. Mogil

DOI

2015

Different immune cells mediate mechanical pain hypersensitivity in male and female mice

R. Sorge, Josiane C. S. Mapplebeck, S. Rosen, S. Beggs, Sarah R Taves, Jessica K. Alexander, Loren J. Martin, J. Austin, S. Sotocinal, Di Chen, Mu Yang, Xiang Q. Shi, Hao Huang, Nicolas J. Pillon, P. J. Bilan, Yu-Shan Tu, A. Klip, R. Ji, Ji Zhang, M. Salter, J. Mogil

Nature Neuroscience

DOI

2014

蛛网膜下腔出血后血管平滑肌细胞凋亡的microRNA芯片检测及分析

李英博，赵香琴，姜英虹，陈笛，王莎莉

《重庆医科大学学报》

2011

藁苯内酯对大鼠蛛网膜下腔出血的神经保护作用及其机制的研究

陈笛

《重庆医科大学》

2003

人参总皂甙诱导人骨髓基质细胞表达GM-CSF的实验研究

陈笛，王莎莉，王亚平，王璐，姜蓉

《重庆医科大学学报》

2003

人参总皂甙对人GM-CSF和GM-CSFR表达的调控

王莎莉，陈笛，王亚平，刘永刚，姜蓉

《生理学报》

2003

成人骨髓间充质干细胞分化为神经元样细胞的体外研究

李云玲，陈笛，王璐，江和碧，卓本慧，梁熙，李廷玉

《陆军军医大学学报》

陈笛

精选作品

期刊论文

重复经颅磁刺激联合丁苯酞治疗帕金森病患者的效果观察

复方苁蓉益智胶囊联合银杏叶提取物对VCIND患者认知功能和血清BDNF、MMP-9水平影响的研究

MCA急性脑梗死患者药物溶栓治疗的预后影响因素分析

免疫球蛋白联合甲泼尼龙治疗自身免疫性脑炎的效果观察

高压氧联合醒脑静注射液及艾地苯醌片治疗血管性痴呆的疗效及对患者脑血流状态、氧化应激反应的影响

Behavioral Abnormalities, Cognitive Impairments, Synaptic Deficits, and Gene Replacement Therapy in a CRISPR Engineered Rat Model of 5p15.2 Deletion Associated With Cri du Chat Syndrome

橘皮素调控PI3K/Akt信号通路介导的自噬对脑缺血/再灌注损伤大鼠神经细胞焦亡的影响

早期康复护理对NMOSD患者症状评分、生活活动能力的影响

日常饮食中添加摄食甜菜碱对APP/PS1转基因小鼠的影响

Melatonin ameliorates sleep-wake disturbances and autism-like behaviors in the Ctnnd2 knock out mouse model of autism spectrum disorders

Associations of DNA Methylation With Behavioral Problems, Gray Matter Volumes, and Negative Life Events Across Adolescence: Evidence From the Longitudinal IMAGEN Study

miR-124通过抑制TLR4/NF-κB/CCL2对脑梗死大鼠神经元凋亡的影响

支架取栓术联合替罗非班及丁苯酞治疗急性脑梗死的效果

老年腔隙性脑梗死合并高血压患者认知功能障碍影响因素分析及25-羟基维生素D的预测价值

Brain Signatures During Reward Anticipation Predict Persistent Attention-Deficit/Hyperactivity Disorder Symptoms

Progranulin improves neural development via the PI3K/Akt/GSK-3β pathway in the cerebellum of a VPA-induced rat model of ASD

Neural Biomarkers Distinguish Severe From Mild Autism Spectrum Disorder Among High-Functioning Individuals

Abnormal spatiotemporal expression pattern of progranulin and neurodevelopment impairment in VPA-induced ASD rat model

藁本内酯对大鼠蛛网膜下腔出血后迟发性血管痉挛的影响

δ-联蛋白通过AKT信号通路调控OGD/R后的炎症反应

[Improvement of a mouse model of valproic acid-induced autism].

Male-Specific Conditioned Pain Hypersensitivity in Mice and Humans.

4-苯基丁酸钠通过抑制内质网应激减轻皮层神经元氧糖剥夺/再灌注损伤

Protective Effects of Notoginsenoside R1 via Regulation of the PI3K-Akt-mTOR/JNK Pathway in Neonatal Cerebral Hypoxic–Ischemic Brain Injury

A Developmental Study of Abnormal Behaviors and Altered GABAergic Signaling in the VPA-Treated Rat Model of Autism

Protective effects of transient receptor potential canonical channels on oxygen–glucose deprivation-induced cell injury in neurons and PC12 cells

大鼠蛛网膜下腔出血致脑血管痉挛模型的建立

(345) Male-specific conditioned pain hypersensitivity in mice and humans

Different immune cells mediate mechanical pain hypersensitivity in male and female mice

蛛网膜下腔出血后血管平滑肌细胞凋亡的microRNA芯片检测及分析

藁苯内酯对大鼠蛛网膜下腔出血的神经保护作用及其机制的研究

人参总皂甙诱导人骨髓基质细胞表达GM-CSF的实验研究

人参总皂甙对人GM-CSF和GM-CSFR表达的调控

成人骨髓间充质干细胞分化为神经元样细胞的体外研究

研究方向