何春江｜华中农业大学｜学者主页

2026

Overview of circular RNA databases and other resources.

Xian-feng Li, Chunjiang He

Nature reviews. Molecular cell biology

DOI

2025

Single-cell sequencing reveals the expansion and diversity of T cell subsets in the bone marrow microenvironment of chronic myeloid leukemia

Chenjian Zhuo, Xin Dong, Xueya Zhao, Weiru Wu, Hao Zhou, Jing Feng, Lingbo Liu, Mingqian Feng, Chunjiang He, Yu Hou

Genes & Diseases

DOI

2025

circAFF2 promotes the development of AML by binding to PML mRNA

Yao Lei, Xinyang Zhang, Xiaoqing Li, Jin Xu, Siqi Yang, Fengyue Li, Wenbo Chen, Yuxin Shan, Linli Ren, Chenjian Zhuo, Sisi Liang, Lu Chen, Weinan Yin, Hudan Liu, Lingbo Liu, Mingqian Feng, Ke Chen, Shuliang Chen, Chunjiang He

Oncogene

DOI

2024

A global view of altered ligand-receptor interactions in bone marrow aging based on single-cell sequencing

Wenbo Chen, Xin Chen, Lei Yao, Jing Feng, Fengyue Li, Yuxin Shan, Linli Ren, Chenjian Zhuo, Mingqian Feng, Shan Zhong, Chunjiang He

Computational and Structural Biotechnology Journal

DOI

2023

Large-scale benchmarking of circRNA detection tools reveals large differences in sensitivity but not in precision

Marieke Vromman, J. Anckaert, S. Bortoluzzi, Alessia Buratin, Chia-Ying Chen, Qin-Jie Chu, Trees-Juen Chuang, Roozbeh Dehghannasiri, C. Dieterich, Xin Dong, P. Flicek, E. Gaffo, Wanjun Gu, Chunjiang He, Steve Hoffmann, Osagie G. Izuogu, M. Jackson, Tobias Jakobi, E. Lai, J. Nuytens, J. Salzman, M. Santibanez-Koref, P. Stadler, O. Thas, E. V. Eynde, Kimberly Verniers, Guoxia Wen, J. Westholm, Li Yang, C. Ye, N. Yigit, Guoliang Yuan, Jin-Yang Zhang, Fangqing Zhao, J. Vandesompele, P. Volders

bioRxiv

DOI

2023

Genome-wide characterization of alternative splicing in blood cells of COVID-19 and respiratory infections of relevance

Rui Huang, Wenbo Chen, XueYa Zhao, Yue-Fei Ma, Qiong Zhou, Junsen Chen, Muyi Zhang, Dingran Zhao, Yu Hou, Chunjiang He, Ying Wu

Virologica Sinica

DOI

2022

circRIP: an accurate tool for identifying circRNA-RBP interactions

Xin Dong, Ke Chen, Wenbo Chen, Jun Wang, Liuping Chang, Jin Deng, Lei Wei, Leng Han, Chunhua Huang, Chunjiang He

Briefings Bioinform.

DOI

2021

CSCD2: an integrated interactional database of cancer-specific circular RNAs

Jing Feng, Wenbo Chen, Xin Dong, Jun Wang, Xiangfei Mei, J. Deng, S. Yang, Chenjian Zhuo, Xiaoyu Huang, Lin Shao, Rongyu Zhang, Jing Guo, Ronghui Ma, Juan Liu, Feng Li, Ying Wu, Leng Han, Chunjiang He

Nucleic Acids Res.

DOI

2021

ADEIP: an integrated platform of age-dependent expression and immune profiles across human tissues

Xuan Liu, Wenbo Chen, Yu Fang, S. Yang, Liuping Chang, Xingyu Chen, Hai-dan Ye, Xin-Yu Tang, Shan Zhong, Wen Zhang, Zhiqiang Dong, Leng Han, Chunjiang He

Briefings Bioinform.

DOI

2021

Circular RNA circYPEL2: A Novel Biomarker in Cervical Cancer

Xin-Yang Zhang, S. Yang, Wenbo Chen, Xin Dong, Rongyu Zhang, Hai-dan Ye, Xiangfei Mei, Huan Liu, Yu Fang, Chunjiang He

Genes

DOI

2021

Silencing of circIgf1r plays a protective role in neuronal injury via regulating astrocyte polarization during epilepsy

Lin Shao, Guang-Tong Jiang, Xing-Liang Yang, Meng-liu Zeng, Jing-Jing Cheng, Shuo Kong, Xin Dong, Tao-Xiang Chen, Song Han, Jun Yin, Wan-Hong Liu, Xiao-Hua He, Chunjiang He, Bi-Wen Peng

The FASEB Journal

DOI

2021

YTHDF1 promotes mRNA degradation via YTHDF1‐AGO2 interaction and phase separation

Jiong Li, Ke Chen, Xin Dong, Yating Xu, Qi Sun, Hong-Hong Wang, Zhen Chen, Cong Liu, Rong Liu, Zhe Yang, Xiangfei Mei, Rongyu Zhang, Liuping Chang, Zongwen Tian, Jianjun Chen, Kaiwei Liang, Chunjiang He, Mengcheng Luo

Cell Proliferation

DOI

2020

CircRNA inhibits DNA damage repair by interacting with host gene

Xiaolong Xu, Jingwei Zhang, Yihao Tian, Yang Gao, Xin Dong, Wenbo Chen, Xiaoning Yuan, Weinan Yin, Jinjing Xu, Ke Chen, Chunjiang He, Lei Wei

Molecular Cancer

DOI

2019

Genome-wide identification of cancer-specific alternative splicing in circRNA

Jing Feng, Ke Chen, Xin Dong, Xiaolong Xu, Yuxuan Jin, Xin-Yang Zhang, Wenbo Chen, Yujing Han, Lin Shao, Yang Gao, Chunjiang He

Molecular Cancer

DOI

2019

The RNA N6-methyladenosine modification landscape of human fetal tissues

Shan Xiao, Shuo Cao, Qitao Huang, Linjian Xia, Mingqiang Deng, Mengtian Yang, Gui-Zhen Jia, Xiaona Liu, Junfang Shi, Weishi Wang, Yuan Li, Sun Liu, Haoran Zhu, Kai-Fen Tan, Qizhi Luo, M. Zhong, Chunjiang He, Lai-Xin Xia

Nature Cell Biology

DOI

2019

CircView: a visualization and exploration tool for circular RNAs

Jing Feng, Yu Xiang, S. Xia, Huan-Huan Liu, Jun Wang, F. M. Ozguc, Lijun Lei, Ruoshan Kong, L. Diao, Chunjiang He, Leng Han

Briefings in Bioinformatics

DOI

2019

CVm6A: A Visualization and Exploration Database for m6As in Cell Lines

Yujing Han, Jing Feng, Lin-Jian Xia, Xin Dong, Xin-Yang Zhang, Shihan Zhang, Yuqi Miao, Qi-Di Xu, Shan Xiao, Z. Zuo, Laixin Xia, Chunjiang He

Cells

DOI

2017

LincRNAs: Systemic Computational Identification and Functional Exploration

Hanyang Hu, Kitchener D. Wilson, Shan Zhong, Chunjiang He

DOI

2017

CSCD: a database for cancer-specific circular RNAs

S. Xia, Jing Feng, Ke Chen, Yanbing Ma, Jing Gong, F. Cai, Yuxuan Jin, Yang Gao, Linjian Xia, Hong Chang, Lei Wei, Leng Han, Chunjiang He

Nucleic Acids Res.

DOI

2017

Targeted Inhibition of STAT/TET1 Axis As a Potent Therapeutic Strategy for Acute Myeloid Leukemia

Xi Jiang, Chao Hu, K. Ferchen, Ji Nie, Xiaolong Cui, Chih-Hong Chen, Liting Cheng, Z. Zuo, W. Seibel, Chunjiang He, Yixuan Tang, J. Skibbe, M. Wunderlich, W. Reinhold, Lei Dong, Chao Shen, S. Arnovitz, Bryan Ulrich, Jiuwei Lu, Hengyou Weng, R. Su, Huilin Huang, Yun-Gui Wang, Chen-Ying Li, Xi Qin, J. Mulloy, Yi Zheng, Jiajie Diao, Jie Jin, Chong Li, Paul Liu, Chuan He, Yuan Chen, Jianjun Chen

DOI

2016

Comprehensive characterization of tissue-specific circular RNAs in the human and mouse genomes

S. Xia, Jing Feng, Lijun Lei, Jun Hu, Linjian Xia, Jun Wang, Yu Xiang, Lingjun Liu, Shan Zhong, Leng Han, Chunjiang He

Briefings Bioinform.

DOI

2016

Induced Pluripotent Stem Cell – Derived Cardiomyocytes Elucidate Single-Cell Phenotype of Brugada Syndrome

Ping Liang, Karim Sallam, Haodi Wu, Ying-Xin Li, Ilanit Itzhaki, Priyanka Garg, Ying Zhang, Vittavat Vermglinchan, Feng Lan, Mingxia Gu, Tingyu Gong, Y. Zhuge, Chunjiang He, Antje D. Ebert, V. Sanchez-Freire, Jared M. Churko, Shi-Jun Hu, Arun Sharma, C. Lam, M. Scheinman, D. Bers, Joseph C. Wu

2016

Systematic Characterization of Long Non-Coding RNAs Reveals the Contrasting Coordination of Cis- and Trans- Molecular Regulation in Human Fetal and Adult Heart

Chunjiang He, Hanyang Hu, Kitchener D. Wilson, Haodi Wu, Jing Feng, S. Xia, Jared M. Churko, K. Qu, Howard Y. Chang, Joseph C. Wu

Circulation: Cardiovascular Genetics

DOI

2015

Pravastatin reverses obesity-induced dysfunction of induced pluripotent stem cell-derived endothelial cells via a nitric oxide-dependent mechanism.

Mingxia Gu, N. Mordwinkin, N. Kooreman, Jaecheol Lee, Haodi Wu, Shi-Jun Hu, Jared M. Churko, Sebastian Diecke, P. Burridge, Chunjiang He, Frances E Barron, S. Ong, J. Gold, Joseph C. Wu

European Heart Journal

DOI

2013

Identification of a 24-gene prognostic signature that improves the European LeukemiaNet risk classification of acute myeloid leukemia: an international collaborative study.

Ze-Juan Li, T. Herold, Chunjiang He, P. Valk, Ping Chen, V. Jurinovic, U. Mansmann, M. Radmacher, K. Maharry, Miao Sun, Xinan H Yang, Hao Huang, Xi Jiang, M. Sauerland, T. Büchner, W. Hiddemann, A. Elkahloun, Mary Beth Neilly, Yan-Ming Zhang, R. Larson, M. L. Le Beau, M. Caligiuri, K. Döhner, L. Bullinger, Paul Liu, R. Delwel, G. Marcucci, B. Lowenberg, C. Bloomfield, J. Rowley, S. Bohlander, Jianjun Chen

Journal of Clinical Oncology

DOI

2013

TET1 plays an essential oncogenic role in MLL-rearranged leukemia

Hao Huang, Xi Jiang, Ze-Juan Li, Yuan-Yuan Li, Chun-Xiao Song, Chunjiang He, Miao Sun, Ping Chen, S. Gurbuxani, Jiapeng Wang, Gia-ming Hong, A. Elkahloun, S. Arnovitz, Jinhua Wang, Keith E. Szulwach, Li Lin, Craig Street, M. Wunderlich, M. Dawlaty, Mary Beth Neilly, R. Jaenisch, Feng-Chun Yang, J. Mulloy, P. Jin, Paul Liu, J. Rowley, Ming-Jiang Xu, Chuan He, Jianjun Chen

Proceedings of the National Academy of Sciences of the United States of America

DOI

2013

PBX3 is an important cofactor of HOXA9 in leukemogenesis.

Ze-Juan Li, Zhiyu Zhang, Yuan-Yuan Li, S. Arnovitz, Ping Chen, Hao Huang, Xi Jiang, Gia-ming Hong, Rejani B. Kunjamma, Hao-Min Ren, Chunjiang He, Chong-Zhi Wang, A. Elkahloun, P. Valk, K. Döhner, Mary Beth Neilly, L. Bullinger, R. Delwel, B. Lowenberg, Paul Liu, Richard Morgan, J. Rowley, Chun-Su Yuan, Jianjun Chen

Blood

DOI

2013

MLL-Rearranged Acute Myeloid Leukemias Drive Expression Of Mir-9, a Critical Oncogene In Leukemogenesis

Ping Chen, Ze-Juan Li, Yuan-Yuan Li, A. Wiley, Chunjiang He, Rejani B. Kunjamma, Hao Huang, Xi Jiang, S. Arnovitz, Mary Beth Neilly, J. Rowley, Jianjun Chen

DOI

2013

The Role of SIRT6 Protein in Aging and Reprogramming of Human Induced Pluripotent Stem Cells*

Amit Sharma, Sebastian Diecke, Wendy Y. Zhang, Feng Lan, Chunjiang He, N. Mordwinkin, Katrin F. Chua, Joseph C. Wu

Journal of Biological Chemistry

DOI

2013

Abstract 16710: Induced Pluripotent Stem Cell-Derived Endothelial Cells From Diet-Induced Obesity Mice Exhibit Decreased Vascular Function in a Murine Model of Hindlimb Ischemia

N. Mordwinkin, Mingxia Gu, N. Kooreman, Shi-Jun Hu, Jared M. Churko, Sebastian Diecke, P. Burridge, Chunjiang He, Jaechol Lee, J. Gold, Joseph C. Wu

2012

MLL-Associated Leukemias Drive Expression of MiR-9, Required for Tumorigenesis

C. Price, Ping Chen, Ze-Juan Li, Yuan-Yuan Li, A. Wiley, Chunjiang He, Rejani B. Kunjamma, Hao Huang, Xi Jiang, S. Arnovitz, Mary Beth Neilly, J. Rowley, Jianjun Chen

DOI

2012

Up-regulation of a HOXA-PBX3 homeobox-gene signature following down-regulation of miR-181 is associated with adverse prognosis in patients with cytogenetically abnormal AML.

Ze-Juan Li, Hao Huang, Yuan-Yuan Li, Xi Jiang, Ping Chen, S. Arnovitz, M. Radmacher, K. Maharry, A. Elkahloun, Xinan H Yang, Chunjiang He, Miao He, Zhiyu Zhang, K. Döhner, Mary Beth Neilly, C. Price, Y. Lussier, Yan-Ming Zhang, R. Larson, M. L. Le Beau, M. Caligiuri, L. Bullinger, P. Valk, R. Delwel, B. Lowenberg, Paul Liu, G. Marcucci, C. Bloomfield, J. Rowley, Jianjun Chen

Blood

DOI

2012

Blockade of miR-150 maturation by MLL-fusion/MYC/LIN-28 is required for MLL-associated leukemia

Xi Jiang, Hao Huang, Ze-Juan Li, Yuan-Yuan Li, Xiao Wang, S. Gurbuxani, Ping Chen, Chunjiang He, De-Wen You, Shuo-Dan Zhang, Jinhua Wang, S. Arnovitz, A. Elkahloun, C. Price, Gia-ming Hong, Hao-Min Ren, Rejani B. Kunjamma, Mary Beth Neilly, J. Matthews, Meng-Yi Xu, R. Larson, M. L. Le Beau, R. Slany, Paul Liu, Jun Lu, Ji-Wang Zhang, Chuan He, Jianjun Chen

Cancer Cell

DOI

2012

The HOXA/PBX3 Pathway Is an Attractive Therapeutic Target in MLL-Rearranged Acute Leukemia

Ze-Juan Li, Zhiyu Zhang, Yuan-Yuan Li, S. Arnovitz, Ping Chen, Hao Huang, Xi Jiang, Gia-ming Hong, Chunjiang He, Chong-Zhi Wang, A. Elkahloun, P. Valk, K. Döhner, Mary Beth Neilly, L. Bullinger, R. Delwel, B. Lowenberg, P. Liu, Richard Morgan, J. Rowley, Chun-Su Yuan, Jianjun Chen

DOI

2012

Abstract 2309: Down-regulation of miR-181b contributes to the poor prognosis of adverse cytogenetically abnormal acute myeloid leukemia by targeting PBX3

Ze-Juan Li, Hao Huang, Yuan-Yuan Li, Xi Jiang, Ping Chen, S. Arnovitz, Chunjiang He, Zhi-Yu Zhang, Mary Beth Neilly, C. Price, Yan-Ming Zhang, R. Larson, M. L. Le Beau, J. Rowley, Jianjun Chen

DOI

2011

MLL-Rearrangements Result in Upregulation of Mir-9 and Subsequent Inhibition of the Tumor Suppressor TGFBI

C. Price, Ping Chen, Ze-Juan Li, Yuan-Yuan Li, A. Wiley, Chunjiang He, Hao Huang, Xi Jiang, S. Arnovitz, Mary Beth Neilly, J. Rowley, Jianjun Chen

DOI

2011

Activation of a Mir-181-Targeting HOXA-PBX3 Homeobox Gene Signature Is Associated with Adverse Prognosis of Cytogenetically Abnormal Acute Myeloid Leukemia

Ze-Juan Li, Hao Huang, Yuan-Yuan Li, Xi Jiang, Ping Chen, S. Arnovitz, M. Radmacher, K. Maharry, A. Elkahloun, Xinan H Yang, Chunjiang He, C. Price, K. Döhner, Zhiyu Zhang, Chen Shen, Mary Beth Neilly, Y. Lussier, Yan-Ming Zhang, R. Larson, Michelle M. Le Beau, M. Caligiuri, L. Bullinger, P. Valk, R. Delwel, B. Lowenberg, Paul Liu, G. Marcucci, C. Bloomfield, J. Rowley, Jianjun Chen

DOI

2011

Repression of Mir-495, a Microrna Associated with Favorable Outcome of Acute Myeloid Leukemia Patients, Is Required for the MLL -Associated Leukemogenesis,

Xi Jiang, Hao Huang, Ze-Juan Li, Yuan-Yuan Li, Ping Chen, Chunjiang He, S. Arnovitz, Mary Beth Neilly, J. Rowley, Jianjun Chen

DOI

2010

Aberrant overexpression and function of the miR-17-92 cluster in MLL-rearranged acute leukemia

Shuangli Mi, Ze-Juan Li, Ping Chen, Chunjiang He, Dong-Lin Cao, A. Elkahloun, Jun Lu, L. A. Pelloso, M. Wunderlich, Hao Huang, R. Luo, Miao Sun, Miao He, Mary Beth Neilly, N. Zeleznik-Le, M. Thirman, J. Mulloy, Paul Liu, J. Rowley, Jianjun Chen

Proceedings of the National Academy of Sciences of the United States of America

DOI

2010

MicroRNAs expression signatures are associated with lineage and survival in acute leukemias

Yun-Gui Wang, Ze-Juan Li, Chunjiang He, Dongmei Wang, Xiang-Qui Yuan, Jianjun Chen, Jie Jin

Blood Cells, Molecules & Diseases

DOI

2009

A Global View of Cancer-Specific Transcript Variants by Subtractive Transcriptome-Wide Analysis

Chunjiang He, Fang Zhou, Z. Zuo, Han-Hua Cheng, Rongjia Zhou

PLoS ONE

DOI

2007

Genome-wide detection of testis- and testicular cancer-specific alternative splicing.

Chunjiang He, Z. Zuo, Heng-Ling Chen, Liao Zhang, Fang Zhou, Han-Hua Cheng, Rongjia Zhou

Carcinogenesis

DOI

2007

GATA family of transcription factors of vertebrates: phylogenetics and chromosomal synteny

Chunjiang He, Han-Hua Cheng, Rongjia Zhou

Journal of Biosciences

DOI

精选作品

期刊论文

Overview of circular RNA databases and other resources.

Single-cell sequencing reveals the expansion and diversity of T cell subsets in the bone marrow microenvironment of chronic myeloid leukemia

circAFF2 promotes the development of AML by binding to PML mRNA

A global view of altered ligand-receptor interactions in bone marrow aging based on single-cell sequencing

Large-scale benchmarking of circRNA detection tools reveals large differences in sensitivity but not in precision

Genome-wide characterization of alternative splicing in blood cells of COVID-19 and respiratory infections of relevance

circRIP: an accurate tool for identifying circRNA-RBP interactions

CSCD2: an integrated interactional database of cancer-specific circular RNAs

ADEIP: an integrated platform of age-dependent expression and immune profiles across human tissues

Circular RNA circYPEL2: A Novel Biomarker in Cervical Cancer

Silencing of circIgf1r plays a protective role in neuronal injury via regulating astrocyte polarization during epilepsy

YTHDF1 promotes mRNA degradation via YTHDF1‐AGO2 interaction and phase separation

CircRNA inhibits DNA damage repair by interacting with host gene

Genome-wide identification of cancer-specific alternative splicing in circRNA

The RNA N6-methyladenosine modification landscape of human fetal tissues

CircView: a visualization and exploration tool for circular RNAs

CVm6A: A Visualization and Exploration Database for m6As in Cell Lines

LincRNAs: Systemic Computational Identification and Functional Exploration

CSCD: a database for cancer-specific circular RNAs

Targeted Inhibition of STAT/TET1 Axis As a Potent Therapeutic Strategy for Acute Myeloid Leukemia

Comprehensive characterization of tissue-specific circular RNAs in the human and mouse genomes

Induced Pluripotent Stem Cell – Derived Cardiomyocytes Elucidate Single-Cell Phenotype of Brugada Syndrome

Systematic Characterization of Long Non-Coding RNAs Reveals the Contrasting Coordination of Cis- and Trans- Molecular Regulation in Human Fetal and Adult Heart

Pravastatin reverses obesity-induced dysfunction of induced pluripotent stem cell-derived endothelial cells via a nitric oxide-dependent mechanism.

Identification of a 24-gene prognostic signature that improves the European LeukemiaNet risk classification of acute myeloid leukemia: an international collaborative study.

TET1 plays an essential oncogenic role in MLL-rearranged leukemia

PBX3 is an important cofactor of HOXA9 in leukemogenesis.

MLL-Rearranged Acute Myeloid Leukemias Drive Expression Of Mir-9, a Critical Oncogene In Leukemogenesis

The Role of SIRT6 Protein in Aging and Reprogramming of Human Induced Pluripotent Stem Cells*

Abstract 16710: Induced Pluripotent Stem Cell-Derived Endothelial Cells From Diet-Induced Obesity Mice Exhibit Decreased Vascular Function in a Murine Model of Hindlimb Ischemia

MLL-Associated Leukemias Drive Expression of MiR-9, Required for Tumorigenesis

Up-regulation of a HOXA-PBX3 homeobox-gene signature following down-regulation of miR-181 is associated with adverse prognosis in patients with cytogenetically abnormal AML.

Blockade of miR-150 maturation by MLL-fusion/MYC/LIN-28 is required for MLL-associated leukemia

The HOXA/PBX3 Pathway Is an Attractive Therapeutic Target in MLL-Rearranged Acute Leukemia

Abstract 2309: Down-regulation of miR-181b contributes to the poor prognosis of adverse cytogenetically abnormal acute myeloid leukemia by targeting PBX3

MLL-Rearrangements Result in Upregulation of Mir-9 and Subsequent Inhibition of the Tumor Suppressor TGFBI

Activation of a Mir-181-Targeting HOXA-PBX3 Homeobox Gene Signature Is Associated with Adverse Prognosis of Cytogenetically Abnormal Acute Myeloid Leukemia

Repression of Mir-495, a Microrna Associated with Favorable Outcome of Acute Myeloid Leukemia Patients, Is Required for the MLL -Associated Leukemogenesis,

Aberrant overexpression and function of the miR-17-92 cluster in MLL-rearranged acute leukemia

MicroRNAs expression signatures are associated with lineage and survival in acute leukemias

A Global View of Cancer-Specific Transcript Variants by Subtractive Transcriptome-Wide Analysis

Genome-wide detection of testis- and testicular cancer-specific alternative splicing.

GATA family of transcription factors of vertebrates: phylogenetics and chromosomal synteny

会议论文

人类及小鼠testes特异选择性剪接数据库的构建

利用EST分析人类及小鼠的睾丸特异的选择性剪接

研究方向