左建宏｜南华大学｜学者主页

2026

Lactylation enzymes in cancer: Mechanisms and novel therapeutic approaches (Review)

Gui-Yang Tang, Hanrong Zuo, Rou Long, Chao-Hui Zhang, Yu-Fan Lv, Xinyu Luo, Jieya Qiu, Jianhong Zuo

Oncology Letters

2025

Antibody-drug conjugates in cancer therapy: applications and future advances

Rou Long, Hanrong Zuo, Guiyang Tang, Chaohui Zhang, Xinru Yue, Jinsai Yang, Xinyu Luo, Yuqi Deng, Jie-Ya Qiu, Jiale Li, Jianhong Zuo

Frontiers in Immunology

DOI

2024

Gamma delta T cells in cancer therapy: from tumor recognition to novel treatments

Xinyu Luo, Yufan Lv, Jinsai Yang, Rou Long, Jie-Ya Qiu, Yuqi Deng, Guiyang Tang, Chaohui Zhang, Jiale Li, Jianhong Zuo

Frontiers in Medicine

DOI

2024

Deep Learning-Based Multimodal Integrated Risk Stratification Prediction Model for Non-Small Cell Lung Cancer

Jinsai Yang, Jianhong Zuo

DOI

2024

Prospects and challenges of CAR-T cell therapy combined with ICIs

Yu-Fan Lv, Xinyu Luo, Zhuo-Yi Xie, Jieya Qiu, Jinsai Yang, Yuqi Deng, Rou Long, Gui-Yang Tang, Chao-Hui Zhang, Jianhong Zuo

Frontiers in Oncology

DOI

2023

Application value of whole exome sequencing in screening and identifying novel mutations of hypopharyngeal cancer

Jingwei Yao, Yubo Ding, Xiong Liu, Jialu Huang, Minghui Zhang, Yu Zhang, Yufan Lv, Zhuoyi Xie, Jianhong Zuo

Scientific Reports

DOI

2022

Research Progress and Direction of Novel Organelle—Migrasomes

Yu Zhang, Minghui Zhang, Zhuoyi Xie, Yubo Ding, Jialu Huang, Jingwei Yao, Yufan Lv, Jianhong Zuo

Cancers

DOI

2022

Regulating the Expression of HIF-1α or lncRNA: Potential Directions for Cancer Therapy

Minghui Zhang, Yu Zhang, Yubo Ding, Jialu Huang, Jingwei Yao, Zhuoyi Xie, Yufan Lv, Jianhong Zuo

Cells

DOI

2022

The potential, analysis and prospect of ctDNA sequencing in hepatocellular carcinoma

Yubo Ding, Jingwei Yao, Meiling Wen, Xiong Liu, Jialu Huang, Minghui Zhang, Yu Zhang, Yufan Lv, Zhuoyi Xie, Jianhong Zuo

PeerJ

DOI

2021

miR-455-5p在恶性肿瘤中作用机制的研究进展

曾蒙颖，雷鸣，易碧云，左建宏

《中国现代医药杂志》

2021

The effect of surgery plus intensity-modulated radiotherapy on treatment in laryngeal cancer: A clinical retrospective study

Kun Deng, Jingwei Yao, Shuqing Zeng, Meiling Wen, Jialu Huang, Tao Zhu, Shanyan Liu, Jianhong Zuo

Journal of Cancer Research and Clinical Oncology

DOI

2021

Abnormal alternative splicing promotes tumor resistance in targeted therapy and immunotherapy

Kun Deng, Jingwei Yao, Jialu Huang, Yubo Ding, Jianhong Zuo

Translational Oncology

DOI

2020

卵巢癌的靶向治疗

潘美红，胡云，左建宏

《医学理论与实践》

DOI

2020

Progress in the Understanding of the Mechanism of Tamoxifen Resistance in Breast Cancer

Jingwei Yao, Kun Deng, Jialu Huang, Ruimin Zeng, Jianhong Zuo

Frontiers in Pharmacology

DOI

2020

Down-regulation of PCK2 inhibits the invasion and metastasis of laryngeal carcinoma cells.

Yun Hu, Kun Deng, Meihong Pan, Shanyan Liu, Wenda Li, Jialu Huang, Jinwei Yao, Jianhong Zuo

PubMed

2019

酸敏感离子通道1在肿瘤中的研究进展

胡云，潘美红，左建宏

《中南医学科学杂志》

DOI

2018

IGRT同步化疗治疗局部晚期食管鳞癌多种方案疗效对比

朱小茜，艾小红，廖明初，左建宏

《湖南师范大学学报(医学版)》

2018

舌癌多种治疗方式的临床疗效比较

孙小雅，严汉兴，贺莎，艾小红，左建宏

《中南医学科学杂志》

2018

循环Micro RNA-4516的表达分析对肝癌的诊断与预后评估研究

严汉兴，贺莎，文美玲，陈荣如，孙小雅，胡云，熊强强，张楚红，李赛，吕秀，胡甜，左建宏

《湖南师范大学学报(医学版)》

2018

MicroRNA-4270在肝癌血浆和组织中的检测结果及分析

贺莎，严汉兴，阳学风，陈荣如，胡云，文美玲，左建宏

《中南医学科学杂志》

2017

MicroRNA在肺癌早期诊断及预后中的应用探讨

李赛，左建宏

《世界最新医学信息文摘》

2017

循环microRNA-122a和microRNA-6086在肝癌诊断及预后中的作用

张楚红，胡甜，阳学风，李赛，吕秀，贺莎，严汉兴，谭贻兮，陈荣如，文美玲，李金成，左建宏

《湖南师范大学学报(医学版)》

2017

循环microRNA-1268在肺癌血浆中检测分析及临床意义

李赛，阳学风，胡甜，张楚红，吕秀，贺莎，严汉兴，谭贻兮，陈荣如，文美玲，李金成，左建宏

《湖南师范大学学报(医学版)》

2017

循环miR-4731-3p在肺癌患者血浆中的表达及临床意义

吕秀，雷明盛，贾凤玲，李赛，张楚红，胡甜，贺莎，严汉兴，胡云，陈荣如，谭贻兮，文美玲，左建宏

《中南医学科学杂志》

2017

循环microRNA-4281对肝癌的诊断与预后评估研究

胡甜，李金成，阳学风，张楚红，李赛，吕秀，贺莎，严汉兴，谭贻兮，陈荣如，文美玲，左建宏

《中南医学科学杂志》

2017

The potential value of microRNA-4463 in the prognosis evaluation in hepatocellular carcinoma

Hu Tian, Jincheng Li, Zhang Chuhong, Xiu Lv, Sai Li, Sha He, Hanxing Yan, Yixi Tan, Mingsheng Lei, Meiling Wen, Jianhong Zuo

Genes & Diseases

DOI

2016

肿瘤微环境中Treg细胞和Th17细胞对鼻咽癌进展和预后的影响

蔡曼波，曾益新，邵建永，左建宏

《湖南师范大学学报(医学版)》

2016

IGRT联合DP同步化疗治疗局部晚期食管癌的临床疗效评价

左建宏，严汉兴，杨立，蔡曼波

《湖南师范大学学报(医学版)》

2016

高表达Bcl-2下调喉癌细胞黏附能力的分子机制探讨

左建宏，雷明胜，李金成，文美玲，李赛，吕秀，王雷，谢金龙

《临床与病理杂志》

2016

肿瘤微环境中不同部位CD68+巨噬细胞对鼻咽癌进展和预后的影响

蔡曼波，邵建永，曾益新，左建宏

《中南医学科学杂志》

2016

The role of hypoxia-inducible factors in tumor angiogenesis and cell metabolism

Xiu Lv, Jincheng Li, Zhang Chuhong, Hu Tian, Sai Li, Sha He, Hanxing Yan, Yixi Tan, Mingsheng Lei, Meiling Wen, Jianhong Zuo

Genes & Diseases

DOI

2016

Bcl-2 overexpression contributes to laryngeal carcinoma cell survival by forming a complex with Hsp90β

Sai Li, Jincheng Li, Hu Tian, Zhang Chuhong, Xiu Lv, Sha He, Hanxing Yan, Yixi Tan, Meiling Wen, Mingsheng Lei, Jianhong Zuo

Oncology Reports

DOI

2016

Hypoxia promotes the invasion and metastasis of laryngeal cancer cells via EMT

Jianhong Zuo, Juan Wen, Mingsheng Lei, Meiling Wen, Sai Li, Xiu Lv, Zhaoyang Luo, Gebo Wen

Medical Oncology

DOI

2015

WITHDRAWN: PLGA-Der p1 Vaccine Inhibited Tumor Growth in a Murine Model of Lung Cancer

Jianhong Zuo, Meiling Wen, Mingsheng Lei, Xiaojun Xiao, Zhigang Liu

Archives of Medical Research

DOI

2015

MiR‐210 Links Hypoxia With Cell Proliferation Regulation in Human Laryngocarcinoma Cancer

Jianhong Zuo, Meiling Wen, Mingsheng Lei, Xiang Peng, Xuefeng Yang, Zhigang Liu

Journal of Cellular Biochemistry

DOI

2014

吉西他宾联合奥沙利铂方案介入化学治疗局部复发鼻咽癌的临床观察

文美玲，吕秀，左建宏

《中国现代医学杂志》

2014

Bcl-2蛋白在喉鳞癌中的表达分析

袁恩健，左建宏，张志伟，文娟，罗招阳

《中国农村卫生》

2014

Bcl-2与Ki-67蛋白在喉鳞癌中的表达检测及临床相关性分析

谢金龙，罗招阳，袁恩健，陈永春，左建宏

《中南医学科学杂志》

2014

低氧相关microRNA-210在实体肿瘤研究中的进展

文娟，罗招阳，左建宏

《中南医学科学杂志》

2014

波形蛋白与肿瘤关系的研究进展

范小英，左建宏，罗招阳，郭东铭，文容

《现代生物医学进展》

2012

Bcl-2高表达诱导头颈部鳞癌细胞部分EMT、促进其侵袭和转移机制研究

左建宏

《中南大学》

2011

细胞基质Ⅰ型胶原通过调控β-catenin促进头颈鳞癌细胞转移和增殖

左建宏，李新辉，李茂玉，万恂恂，曾谷清，贺秋艳，李建璜，肖志强

《生物化学与生物物理进展》

2011

EGFR激活对头颈部鳞癌细胞SCC10A抗失巢凋亡的影响

左建宏，吕冬，李金成

《中南医学科学杂志》

2010

肿瘤微环境体外模拟在鼻咽癌研究中的初步应用

吕冬，左建宏，李金成

《临床与病理杂志》

精选作品

期刊论文

Lactylation enzymes in cancer: Mechanisms and novel therapeutic approaches (Review)

Antibody-drug conjugates in cancer therapy: applications and future advances

Gamma delta T cells in cancer therapy: from tumor recognition to novel treatments

Deep Learning-Based Multimodal Integrated Risk Stratification Prediction Model for Non-Small Cell Lung Cancer

Prospects and challenges of CAR-T cell therapy combined with ICIs

Application value of whole exome sequencing in screening and identifying novel mutations of hypopharyngeal cancer

Research Progress and Direction of Novel Organelle—Migrasomes

Regulating the Expression of HIF-1α or lncRNA: Potential Directions for Cancer Therapy

The potential, analysis and prospect of ctDNA sequencing in hepatocellular carcinoma

miR-455-5p在恶性肿瘤中作用机制的研究进展

The effect of surgery plus intensity-modulated radiotherapy on treatment in laryngeal cancer: A clinical retrospective study

Abnormal alternative splicing promotes tumor resistance in targeted therapy and immunotherapy

卵巢癌的靶向治疗

Progress in the Understanding of the Mechanism of Tamoxifen Resistance in Breast Cancer

Down-regulation of PCK2 inhibits the invasion and metastasis of laryngeal carcinoma cells.

酸敏感离子通道1在肿瘤中的研究进展

IGRT同步化疗治疗局部晚期食管鳞癌多种方案疗效对比

舌癌多种治疗方式的临床疗效比较

循环Micro RNA-4516的表达分析对肝癌的诊断与预后评估研究

MicroRNA-4270在肝癌血浆和组织中的检测结果及分析

MicroRNA在肺癌早期诊断及预后中的应用探讨

循环microRNA-122a和microRNA-6086在肝癌诊断及预后中的作用

循环microRNA-1268在肺癌血浆中检测分析及临床意义

循环miR-4731-3p在肺癌患者血浆中的表达及临床意义

循环microRNA-4281对肝癌的诊断与预后评估研究

The potential value of microRNA-4463 in the prognosis evaluation in hepatocellular carcinoma

肿瘤微环境中Treg细胞和Th17细胞对鼻咽癌进展和预后的影响

IGRT联合DP同步化疗治疗局部晚期食管癌的临床疗效评价

高表达Bcl-2下调喉癌细胞黏附能力的分子机制探讨

肿瘤微环境中不同部位CD68+巨噬细胞对鼻咽癌进展和预后的影响

The role of hypoxia-inducible factors in tumor angiogenesis and cell metabolism

Bcl-2 overexpression contributes to laryngeal carcinoma cell survival by forming a complex with Hsp90β

Hypoxia promotes the invasion and metastasis of laryngeal cancer cells via EMT

WITHDRAWN: PLGA-Der p1 Vaccine Inhibited Tumor Growth in a Murine Model of Lung Cancer

MiR‐210 Links Hypoxia With Cell Proliferation Regulation in Human Laryngocarcinoma Cancer

吉西他宾联合奥沙利铂方案介入化学治疗局部复发鼻咽癌的临床观察

Bcl-2蛋白在喉鳞癌中的表达分析

Bcl-2与Ki-67蛋白在喉鳞癌中的表达检测及临床相关性分析

低氧相关microRNA-210在实体肿瘤研究中的进展

波形蛋白与肿瘤关系的研究进展

Bcl-2高表达诱导头颈部鳞癌细胞部分EMT、促进其侵袭和转移机制研究

细胞基质Ⅰ型胶原通过调控β-catenin促进头颈鳞癌细胞转移和增殖

EGFR激活对头颈部鳞癌细胞SCC10A抗失巢凋亡的影响

肿瘤微环境体外模拟在鼻咽癌研究中的初步应用

研究方向