支秀玲｜复旦大学｜学者主页

2026

Hypoxia Upregulation of BACH1 Aggravates Pulmonary Hypertension Through TGFBR2/SMAD Pathways.

Yannan Hou, Qinhan Li, Tong-You Wade Wei, Xiao-Ke Lin, Jieyu Guo, Ping Yuan, Hui Shen, Ya Gao, Qi Pan, Chen Xu, V. Biasin, Yongbo Li, Yunquan He, Jian Wu, Liliang Li, Jiayu Jin, Xiangxiang Wei, Jiayi Lin, Si-Yu Ma, Nan Jiang, Jinghua Ma, Xiuling Zhi, Qingjun Jiang, Le-Feng Qu, Qianqian Liang, Lindi Jiang, E. Osto, J. Shyy, Xin-Hong Wang, Dan Meng

Circulation

精选作品

期刊论文

Hypoxia Upregulation of BACH1 Aggravates Pulmonary Hypertension Through TGFBR2/SMAD Pathways.

LTBP4 deficiency inhibits NLRP3 inflammasome activation in cardiomyocytes and attenuates heart failure in male mice

MEOX1 Coordinates Autocrine‐Paracrine Programs via SPHK1/S1P to Promote Lymph Node Metastasis in Ovarian Cancer

Endothelial MRG15 Is a Mechanosensitive Suppressor of Atherosclerosis

PCSK5 promotes angiogenesis and cardiac repair after myocardial infarction

Neoadjuvant chemotherapy-induced immune remodeling in ovarian cancer: implications for TIL dynamics and combination immunotherapy

The Multifaceted Roles of BACH1 in Disease: Implications for Biological Functions and Therapeutic Applications

BACH1 recruits STAT3 to enhance leukemia inhibitory factor receptor activity and augments the self-renewal capacity of mouse embryonic stem cells

A BACH1 Inhibitor Ameliorates Myocardial Infarction and Limb Ischemia in Mice.

Long non-coding RNA STMN1P2 promotes breast cancer doxorubicin resistance by inhibiting pyroptosis through the hnRNPU-EZH2-TARF6-MALT1-caspase-1 pathway

Betaine-homocysteine methyltransferase protects against acetaminophen-induced acute liver failure via BACH1-SCD1-oleic acid axis

Unraveling the molecular mechanisms of lymph node metastasis in ovarian cancer: focus on MEOX1

Structural and functional insights into the epigenetic regulator MRG15

BACH1 controls hepatic insulin signaling and glucose homeostasis in mice

BACH1 regulates the differentiation of vascular smooth muscle cells from human embryonic stem cells via CARM1-mediated methylation of H3R17.

Cardiac-specific BACH1 ablation attenuates pathological cardiac hypertrophy by inhibiting the Ang II type 1 receptor expression and the Ca2+/CaMKII pathway.

Tumor cell SPTBN1 inhibits M2 polarization of macrophages by suppressing CXCL1 expression

BACH1 deficiency prevents neointima formation and maintains the differentiated phenotype of vascular smooth muscle cells by regulating chromatin accessibility

The Expression and Role Analysis of Methylation-Regulated Differentially Expressed Gene UBE2C in Pan-Cancer, Especially for HGSOC

Deletion of BACH1 Attenuates Atherosclerosis by Reducing Endothelial Inflammation

Anti-cancer Drug Anlotinib Promotes Autophagy and Apoptosis in Breast Cancer.

The PDGF Family Is Associated with Activated Tumor Stroma and Poor Prognosis in Ovarian Cancer

tRNA-derived fragment tRF Lys-CTT-010 promotes triple-negative breast cancer progression by regulating glucose metabolism via G6PC.

SPTBN1 inhibits growth and epithelial-mesenchymal transition in breast cancer by downregulating miR-21.

Single-Cell Analysis Identify Transcription Factor BACH1 as a Master Regulator Gene in Vascular Cells During Aging

Long noncoding RNA ENST00000508435 promotes migration of breast cancer via FXR 1

BACH1 recruits NANOG and histone H3 lysine 4 methyltransferase MLL/SET1 complexes to regulate enhancer–promoter activity and maintains pluripotency

Loss of SPTBN1 Suppresses Autophagy Via SETD7-mediated YAP Methylation in Hepatocellular Carcinoma Initiation and Development

SPTBN1 inhibits inflammatory responses and hepatocarcinogenesis via the stabilization of SOCS1 and downregulation of p65 in hepatocellular carcinoma

Single‐cell RNA analysis on ACE2 expression provides insights into SARS‐CoV‐2 potential entry into the bloodstream and heart injury

Drp1-dependent mitochondrial fission in cardiovascular disease

OTT_A_250066 5443..5453

CDK9 inhibitor CDKI-73 is synergetic lethal with PARP inhibitor olaparib in BRCA1 wide-type ovarian cancer.

SPTBN1 suppresses the progression of epithelial ovarian cancer via SOCS3-mediated blockade of the JAK/STAT3 signaling pathway

lncRNA APOC1P1-3 promoting anoikis-resistance of breast cancer cells

Bach1-induced suppression of angiogenesis is dependent on the BTB domain

SPTBN1 and cancer, which links?

PSAT1 Regulated Oxidation-Reduction Balance Affects the Growth and Prognosis of Epithelial Ovarian Cancer

Protein palmitoylation and its pathophysiological relevance

Anlotinib Inhibits the Growth of Breast Cancer Cells by Promoting Autophagy and Apoptosis via the Akt/GSK-3α Signalling Pathway

CDK9 inhibitor CDKI-73 is synergetic lethal with PARP inhibitor olaparib in BRCA1 wide-type ovarian cancer.

不同专业学生关于分子生物学实验课授课模式倾向性的调查与思考

Epigenetic regulation in diabetic vascular complications.

BTB and CNC homology 1 (Bach1) promotes human ovarian cancer cell metastasis by HMGA2-mediated epithelial-mesenchymal transition.

Depletion of UBE2C reduces ovarian cancer malignancy and reverses cisplatin resistance via downregulating CDK1.

Bach1 regulates self-renewal and impedes mesendodermal differentiation of human embryonic stem cells

Long Non-Coding RNA ENST00000508435 Promotes Breast Cancer Chemoresistance Through Pyroptosis Inhibition

Tryptase promotes breast cancer angiogenesis through PAR-2 mediated endothelial progenitor cell activation

Extracellular 5′‐nucleotidase (CD73) promotes human breast cancer cells growth through AKT/GSK‐3β/β‐catenin/cyclinD1 signaling pathway

Ecto‐5′‐nucleotidase (CD73) is a potential target of hepatocellular carcinoma

Ecto-5′-nucleotidase (CD73) attenuates inflammation after spinal cord injury by promoting macrophages/microglia M2 polarization in mice

PAR2 promotes M1 macrophage polarization and inflammation via FOXO1 pathway

Resveratrol inhibits Extranodal NK/T cell lymphoma through activation of DNA damage response pathway

Steroidogenic Acute Regulatory Protein (StAR) Overexpression Reduces Inflammation and Insulin Resistance in Obese Mice

Steroidogenic acute regulatory protein (StAR) overexpression attenuates HFD-induced hepatic steatosis and insulin resistance.

Trehalose Inhibits A53T Mutant α-Synuclein Overexpression and Neurotoxicity in Transduced PC12 Cells

Upregulation of hydroxysteroid sulfotransferase 2B1b promotes hepatic oval cell proliferation by modulating oxysterol-induced LXR activation in a mouse model of liver injury

A preliminary study of the role of extracellular -5′- nucleotidase in breast cancer stem cells and epithelial-mesenchymal transition

一体化基础医学实验教学体系的构筑与拓展

胆固醇线粒体转运蛋白(StAR)对脂肪酸引起的肝细胞脂质沉积及胰岛素抵抗的作用及其机制

以创新理念培养免疫学实验研究生助教的探索

基础医学实验教学技术人员队伍的能力整合与提升

Activation of protease‑activated receptor‑2 is associated with increased expression of inflammatory factors in the adipose tissues of obese mice.

CD73 regulates vascular smooth muscle cell functions and facilitates atherosclerotic plaque formation

对基础医学专业分子生物学教学的思考与建议

βII‐Spectrin (SPTBN1) suppresses progression of hepatocellular carcinoma and Wnt signaling by regulation of Wnt inhibitor kallistatin

八年制临床医学分子生物学实验教学的思考与建议

Tryptase Promotes Atherosclerotic Plaque Haemorrhage in ApoE-/- Mice

Ecto-5′-nucleotidase (CD73) promotes tumor angiogenesis

Trehalose inhibits wild-type α-synuclein fibrillation and overexpression and protects against the protein neurotoxicity in transduced PC12 cells

Hydroxysteroid Sulfotransferase SULT2B1b Promotes Hepatocellular Carcinoma Cells Proliferation In Vitro and In Vivo

Overexpression of steroidogenic acute regulatory protein in rat aortic endothelial cells attenuates palmitic acid-induced inflammation and reduction in nitric oxide bioavailability

Potential prognostic biomarker CD73 regulates epidermal growth factor receptor expression in human breast cancer

Inhibitory effect of curcumin on the Al(III)-induced Aβ₄₂ aggregation and neurotoxicity in vitro.

Effect of estrogen sulfation by SULT1E1 and PAPSS on the development of estrogen‐dependent cancers

肥大细胞类胰蛋白酶促进动脉粥样硬化斑块内出血

肥大细胞类胰蛋白酶在动脉粥样硬化发生中的作用机制

RNAi‐mediated CD73 suppression induces apoptosis and cell‐cycle arrest in human breast cancer cells