百晓学者学者目录

辛贵忠

副教授、副研究员、博士生导师、教授、研究员，中国药科大学

精选作品

期刊论文

2026

Integrated targeted metabolomics and complementary [α-15N] glutamine tracing reveal glutamine metabolic remodeling associated with RA-ILD

Li Jiang, Luna Shen, Shuting Fang, Fangyuan Sun, Gui-Zhong Xin, Lifang Liu, Jiayi Zheng

Analytica Chimica Acta

DOI

2026

A Metabolism‐Oriented Strategy for Systematic Analysis of the Pharmacological Material Basis of Classic Traditional Chinese Medicine Formulas: Taking Wuao Sanzi Decoction as an Example

Jin‐Jin Liao, Yang-Dan Liu, Lan‐Ying Gao, Gui-Zhong Xin, Yuan Cao, Zi‐Qi Shi

Journal of Separation Science

DOI

2026

Taste and odor metabolomics of Schisandra chinensis flesh and seeds: integration of sensory evaluation, electronic tongue, LC-QTOF-MS/MS, VirtualTaste, and HS-GC-IMS

Tian-Qi Zhang, Lichao Wang, Fang-Tong Liu, Gui-Zhong Xin, Hong-Juan Hou, Jinxiu Liang, Hui Zhang, Tianmin Wang, Deqiang Dou, Xiaowei Zhang, Da-Chuan Zhang, Cheng Qian, Long-Jiao Cong, Ting-Guo Kang, Gui-Rong Chen, Yue-Hua Chen, Hui‐Peng Song

Frontiers in Nutrition

DOI

2026

Unveiling the improvement mechanisms of moist-heat and hot-air treatments on the flavor of Panax quinquefolius

Hong-Juan Hou, Wenhan Pei, Rui‐Bo Sun, Chao Wang, Fang-Tong Liu, Tian-Qi Zhang, Gui-Zhong Xin, Cheng Qian, Mu Zhang, Xin‐Ru Zhang, Zixuan Ding, Hui Zhang, Tian-Min Wang, Ting-Guo Kang, Wang Hai-bo, Yue-Hua Chen, Hui-Peng Song

npj Science of Food

DOI

2026

Precise Synthesis of Highly Branched Angelica dahurica Polysaccharides up to 66 Units Reveals a Minimal Motif for Wound Repair

Jialin Wang, Yang Ruan, Na Zhao, Sixu Lu, Rui Ge, Jing Ling, Chandler K. Wells, Wenbin Shen, Gui-Zhong Xin, Chaofeng Zhang, Lian‐Wen Qi, Xin‐Shan Ye, X Y Qin

Angewandte Chemie

DOI

2026

Integrated transcriptomics, metabolomics, network toxicology and phenotype-based validation unveil the ferroptosis-induced toxicity mechanism of methyl eugenol in zebrafish (Danio rerio)

Xinru Zhang, Yue-Hua Chen, Gui-Zhong Xin, Cheng Qian, Mu Zhang, Xiao-Wei Zhang, Zixuan Ding, Fang-Tong Liu, Hui Zhang, Rui-Bo Sun, Tian-Qi Zhang, Hong-Juan Hou, Ting-Guo Kang, Hui-Peng Song

Journal of Hazardous Materials Advances

DOI

2026

A Biologically Informed Machine Learning Pipeline Uncovers Metabolic Features of Intestinal Barrier Dysfunction

K. Liu, Ze-Yuan Liang, Tong Li, Lian-Zhi Cui, Jia‐Yi Wang, Zi‐Qi Shi, Gui-Zhong Xin

Analytical Chemistry

DOI

2026

Artificial intelligence algorithms drive the deciphering of traditional Chinese medicine by analyzing the chemicalome, targetome, and bioactivome

Huipeng Song, Zeyuan Liang, Xinru Zhang, Fengyao Yang, Mingyue Zheng, Gui-Zhong Xin

Targetome

DOI

2025

“101计划”背景下中药分析学核心课程与教材建设

郑佳逸，辛贵忠，杨杰，戚进，刘丽芳

《高校医学教学研究(电子版)》

2025

蒽醌类泻剂肠道安全性研究进展

郑凯帆，冷泓旭，徐凯旋，蔡文璐，张颖，赵朋飞，谭圣杰，辛贵忠

《中国药物警戒》

DOI

2025

Mass spectral database-based methodologies for the annotation and discovery of natural products

Fengyao Yang, Zeyuan Liang, Haoran Zhao, Jia‐Yi Zheng, Lifang Liu, Hui‐Peng Song, Gui-Zhong Xin

Chinese Journal of Natural Medicines

DOI

2025

Discrimination of easily confused tea leaves with similar appearance (Gougu tea vs. Gonglao tea) via an integrated method of electronic tongue, HPLC-QTOF-MS-VirtualTaste, electronic nose, electrochemical fingerprinting and machine learning

Rui-Bo Sun, Yuehua Chen, Xinru Zhang, Fangtong Liu, Wen-Yu Wang, Jia‐Nuo Zhang, Yifan Wang, Hui Zhang, Ming Yong Xie, Gui-Zhong Xin, Hui‐Peng Song

Journal of Food Composition and Analysis

DOI

2025

A Comprehensive Analysis of Volatile and Nonvolatile Components in Berberis fortunei and Its Inhibition Against HT29 Colorectal Cancer Cells Through GC‐IMS, LC‐QTOF‐MS, and Docking‐Based Network Analysis

Fang‐Tong Liu, Yue‐Hua Chen, Wen‐Yu Wang, Jia‐Nuo Zhang, Rui‐Bo Sun, Xinru Zhang, Yu Han, Zixuan Ding, Hui Zhang, Haibo Yin, Gui-Zhong Xin, Deqiang Dou, Hui‐Peng Song

Phytochemical Analysis

DOI

2025

ROASMI: accelerating small molecule identification by repurposing retention data

Fang-Yuan Sun, Yinghao Yin, Huijun Liu, Lu-Na Shen, Xiu-Lin Kang, Gui-Zhong Xin, Lifang Liu, Jia‐Yi Zheng

Journal of Cheminformatics

DOI

2024

血根碱在癌症治疗中的抗肿瘤机制研究进展

冉遥，冷泓旭，郑凯帆，辛贵忠，濮社班

《中南药学》

2024

Fluorinated chitosan mediated transepithelial delivery of sanguinarine-loaded platinum (IV) prodrug for intravesical instillation therapy of muscle-invasive bladder cancer

Xinzi Hu, Guangzhi Li, Chenfan Kong, Lisha Liu, Dashi Deng, Gui-Zhong Xin, Jian Pan, Song Wu, Qifang Lei

Journal of Controlled Release

DOI

2024

Integrating metabolomics and network pharmacology to investigate Da-Chai-Hu Decoction prevents kidney injury in diabetic mice

Xue Wang, Zhu-Jun Zhong, Pengfei Chen, Chao‐Fan Deng, Xiaomei Chen, Gui-Zhong Xin, Dan Tang

Journal of Ethnopharmacology

DOI

2024

Mass Spectrometry Probe Combined with Machine Learning to Capture the Relationship between Metabolites and Mitochondrial Complex Activity at the Whole-Cell Level

Jia‐Yi Zheng, Xiaoyuan Ji, Anqi Zhao, Fang-Yuan Sun, Lifang Liu, Gui-Zhong Xin

Analytical Chemistry

DOI

2024

Comprehensive exploration of a traditional Chinese medicinal plant of Magnolia officinalis based on high-coverage mass spectrometry and multidimensional chemical-biological analysis

Wen-Yu Wang, Ya‐Mei Song, Jia‐Nuo Zhang, Ming‐Yue Zhao, Wenhan Pei, Hui Zhang, Haibo Yin, Zhili Xu, Gui-Zhong Xin, Ming Yong Xie, Ting-Guo Kang, Yue‐Hua Chen, Hui‐Peng Song

Journal of Chromatography B

DOI

2024

Integration of High-Resolution LC-Q-TOF Mass Spectrometry and Multidimensional Chemical−Biological Analysis to Detect Nanomolar-Level Acetylcholinesterase Inhibitors from Different Parts of Zanthoxylum nitidum

Jia‐Nuo Zhang, Zhi-Dong Pei, Wen-Yu Wang, Ming‐Yue Zhao, Wenhan Pei, Hui Zhang, Haibo Yin, Tian‐Min Wang, Gui-Zhong Xin, Ming Yong Xie, Tingguo Kang, Yuehua Chen, Hui‐Peng Song

Journal of Agricultural and Food Chemistry

DOI

2024

Targeted Quantification of Glutathione/Arginine Redox Metabolism Based on a Novel Paired Mass Spectrometry Probe Approach for the Functional Assessment of Redox Status

Zhu-Jun Zhong, Jing Ling, Zhong‐Ping Yao, Lifang Liu, Jia‐Yi Zheng, Gui-Zhong Xin

Analytical Chemistry

DOI

2024

Enzyme-Driven LC–HRMS Approach for Specific Recognition of 12α-Hydroxy Bile Acids

Anqi Zhao, Jia‐Yi Zheng, Chen Chen, Lifang Liu, Gui-Zhong Xin

Analytical Chemistry

DOI

2024

FNICM: A New Methodology To Identify Core Metabolites Based on Significantly Perturbed Metabolic Subnetworks

Qi Li, Yinghao Yin, Zi-Wei Liu, Lifang Liu, Gui-Zhong Xin

Analytical Chemistry

DOI

2024

Development of target-based cell membrane affinity ultrafiltration technology for a simplified approach to discovering potential bioactive compounds in natural products

Xuan Chen, Jian‐Liang Zhou, Jinhao Yu, Ningbo Chen, Wenda Chen, Huaqiu Lu, Gui-Zhong Xin, Yuanyuan Lin

Analytical and Bioanalytical Chemistry

DOI

2024

Directly capturing native fatty acid synthase from cancer cells by affinity-based probe for precise inhibitor discovery

Lin Yuanyuan, Huaqiu Lu, Jinhao Yu, Xuan Chen, Ningbo Chen, Huamin Zhang, Lu Ye, Yimin Chen, Weiyang Tang, Gui-Zhong Xin, Jian‐Liang Zhou

Chemical Engineering Journal

DOI

2023

Pseudotargeted metabolomics-based random forest model for tracking plant species from herbal products

Wen-Lu Cai, Can Fang, Lifang Liu, Fang-Yuan Sun, Gui-Zhong Xin, Jia‐Yi Zheng

Phytomedicine

DOI

2022

天然多糖改善溃疡性结肠炎的作用机制研究进展

孙亚哲，王鑫楠，辛贵忠，刘丽芳

《中医药学报》

2022

进展性导向下的中药分析学教材建设与教学应用

辛贵忠，杨杰，郑佳逸，刘丽芳

《药学教育》

2022

An in-house database-driven untargeted identification strategy for deep profiling of chemicalome in Chinese medicinal formula

Kexin Liu, Ning Li, Yinghao Yin, Zhu-Jun Zhong, Ping Li, Lifang Liu, Gui-Zhong Xin

Journal of Chromatography A

DOI

2022

Least absolute shrinkage and selection operator-based prediction of collision cross section values for ion mobility mass spectrometric analysis of lipids

Jian-Ying Wang, Yinghao Yin, Jia‐Yi Zheng, Lifang Liu, Zhong‐Ping Yao, Gui-Zhong Xin

The Analyst

DOI

2021

Targeting tryptophan metabolism reveals Clematichinenoside AR alleviates triptolide-induced hepatotoxicity

Xin-Nan Wang, Wenrui Xia, Jianqun Liu, Fang-Yuan Sun, Zhu-Jun Zhong, Lifang Liu, Gui-Zhong Xin

Journal of Pharmaceutical and Biomedical Analysis

DOI

2021

Design, Synthesis, and Biological Evaluation of Icaritin Derivatives as Novel Putative DEPTOR Inhibitors for Multiple Myeloma Treatment

Yi Hou, Wenbin Kuang, Wenjian Min, Ziwen Liu, Fang Zhang, Kai Yuan, Xiao Wang, Chengliang Sun, Hao Cheng, Liping Wang, Yibei Xiao, She-Ban Pu, Gui-Zhong Xin, Peng Yang

Journal of Medicinal Chemistry

DOI

2021

miR122-controlled all-in-one nanoplatform for in situ theranostic of drug-induced liver injury by visualization imaging guided on-demand drug release

Lingchang Meng, Qiaolei Wang, Lai Wang, Zhen Zhou Zhao, Gui-Zhong Xin, Zu‐Guo Zheng, Ping Zhou, Ping Li, Yan Jiang, Hui‐Jun Li

Materials Today Bio

DOI

2021

Jujube polysaccharides mitigated anemia in rats with chronic kidney disease: Regulation of short chain fatty acids release and erythropoietin production

Shiying Huang, Xue Song Jiang, Qiugu Chen, Zhaoliu Hu, Fochang Wang, Yuan Zhao, Gui-Zhong Xin, Jianping Chen

Journal of Functional Foods

DOI

2021

Measurement of Intracellular Nitric Oxide with a Quantitative Mass Spectrometry Probe Approach

Zhu-Jun Zhong, Zhong‐Ping Yao, Zi‐Qi Shi, Yang-Dan Liu, Lifang Liu, Gui-Zhong Xin

Analytical Chemistry

DOI

2021

Classification-based strategies to simplify complex traditional Chinese medicine (TCM) researches through liquid chromatography-mass spectrometry in the last decade (2011–2020): Theory, technical route and difficulty

Yuehua Chen, Jing-Hua Bi, Ming Xie, Hui Zhang, Zi‐Qi Shi, Hua Guo, Haibo Yin, Jia‐Nuo Zhang, Gui-Zhong Xin, Hui‐Peng Song

Journal of Chromatography A

DOI

2021

Lipidomics characterization of the mechanism of Cynomorium songaricum polysaccharide on treating type 2 diabetes

Zi‐Qi Shi, Lu-Yi Wang, Jia‐Yi Zheng, Gui-Zhong Xin, Lin Chen

Journal of Chromatography B

DOI

2021

Mesoporous silica-mediated controllable electrochemiluminescence quenching for immunosensor with simplicity, sensitivity and tunable detection range

Yi Xiao, Suhua Chen, Simeng Zhang, Guofang Wang, Haomin Yi, Gui-Zhong Xin, Xiaoping Yang

Talanta

DOI

2021

Effects of soy isoflavone supplementation on patients with diabetic nephropathy: a systematic review and meta-analysis of randomized controlled trials

Xue Wang, Qing-Feng Liang, Xia Zeng, Guang-Xiao Huang, Gui-Zhong Xin, Youhua Xu, Shumei Wang, Dan Tang

Food & Function

DOI

2020

抗宫炎方化学成分的UPLC-QTOF MS全面表征

程贤，王鑫楠，辛贵忠，刘丽芳

《沈阳药科大学学报》

DOI

2020

基于UPLC-QTOF/MS技术鉴定雷公藤多苷片中的化学成分

章欣怡，辛贵忠，刘建群，刘丽芳

《中医药学报》

DOI

2020

Fluorous-paired derivatization approach towards highly sensitive and accurate determination of long chain unsaturated fatty acids by liquid chromatography-tandem mass spectrometry

Jia‐Yi Zheng, Yingying Jin, Zi‐Qi Shi, Jian‐Liang Zhou, Lifang Liu, Gui-Zhong Xin

Analytica Chimica Acta

DOI

2020

Multi-omics profiling highlights lipid metabolism alterations in pigs fed low-dose antibiotics

Yue Hu, Yihe Zhang, Cong Liu, Rui Qin, Desheng Gong, Ru Wang, Du Zhang, Lianqiang Che, Daiwen Chen, Gui-Zhong Xin, Fei Gao, Qi Hu

BMC Genetics

DOI

2020

Orthogonal label and label-free dual pretreatment for targeted profiling of neurotransmitters in enteric nervous system

Xin-Nan Wang, Jianqun Liu, Zi‐Qi Shi, Fang-Yuan Sun, Lifang Liu, Gui-Zhong Xin

Analytica Chimica Acta

DOI

2020

Comparative analysis and natural evolution of squalene epoxidase in three Fritillaria species

Xu Lu, Lin-Ning Zhang, Jinfa Du, Xiaoyan Zheng, Hui‐Jun Li, Ping Li, Gui-Zhong Xin, Yan Jiang

Plant Molecular Biology

DOI

2020

Diagnostic fragmentation‐assisted mass spectral networking coupled with in silico dereplication for deep annotation of steroidal alkaloids in medicinal Fritillariae Bulbus

Feng‐Jie Liu, Yan Jiang, Ping Li, Yang‐Dan Liu, Gui-Zhong Xin, Zhong‐Ping Yao, Hui‐Jun Li

Journal of Mass Spectrometry

DOI

2020

Discovery and validation of peptide biomarkers for discrimination of Dendrobium species by label-free proteomics and chemometrics

Can Fang, Gui-Zhong Xin, Shuling Wang, Mengmeng Wei, Pu Wu, Xue-Man Dong, Gao-Qian Song, Tian Xie, Jian‐Liang Zhou

Journal of Pharmaceutical and Biomedical Analysis

DOI

2020

A sensitive upconverting nanoprobe based on signal amplification technology for real-time in situ monitoring of drug-induced liver injury

Lingchang Meng, Xian Zheng, Zu‐Guo Zheng, Zhen Zhou Zhao, Lai Wang, Ping Zhou, Gui-Zhong Xin, Ping Li, Hui‐Jun Li

Nanoscale

DOI

2020

Evaluation of Anti‐Inflammatory Components of Guizhi Fuling Capsule, an Ancient Chinese Herbal Formula, in Human Umbilical Vein Endothelial Cells

Yuzhong Zheng, Gui-Zhong Xin, Guowei Gong, Tina Ting-Xia Dong, Ping Li, Karl Wah Keung Tsim

Evidence-based Complementary and Alternative Medicine

DOI

2019

中草药调控肠道微生态组成与代谢的研究进展

王鑫楠，王维维，辛贵忠，刘丽芳

《中医药学报》

2019

A novel liquid-liquid-solid microextraction strategy for bio-sample preparation by in situ self-assembly of zeolitic imidazolate framework 8 on hollow fiber membrane

Yang-Dan Liu, Gui-Zhong Xin, Wei Li, Feng‐Jie Liu, Zhong‐Ping Yao, Xin Di

Analytica Chimica Acta

DOI

2019

Untargeted metabolomics coupled with chemometric analysis reveals species-specific steroidal alkaloids for the authentication of medicinal Fritillariae Bulbus and relevant products

Feng‐Jie Liu, Yan Jiang, Ping Li, Yang-Dan Liu, Zhong‐Ping Yao, Gui-Zhong Xin, Hui‐Jun Li

Journal of Chromatography A

DOI

2019

Inter-correlated gut microbiota and SCFAs changes upon antibiotics exposure links with rapid body-mass gain in weaned piglet model

Lianqiang Che, Qi Hu, Ru Wang, Du Zhang, Cong Liu, Yihe Zhang, Gui-Zhong Xin, Zhengfeng Fang, Lin Yan, Shengyu Xu, Bin Feng, Daiwen Chen, De Wu, Fei Gao

The Journal of Nutritional Biochemistry

DOI

2019

Saponins from Clematis mandshurica Rupr. regulates gut microbiota and its metabolites during alleviation of collagen-induced arthritis in rats

Lin‐Xiu Guo, Huai‐You Wang, Xue-Duan Liu, Jia‐Yi Zheng, Qi Tang, Xin-Nan Wang, Jianqun Liu, Huaqun Yin, Bo Miao, Yili Liang, Lifang Liu, Gui-Zhong Xin

Pharmacological Research

DOI

2019

In silico production of relative correction factor for the quantitative analysis of multi‐components by single marker method

Yinghao Yin, Jia‐Yi Zheng, Xin-Nan Wang, Sheng‐Ying Qian, Xu‐Yi Liu, Lifang Liu, Gui-Zhong Xin

Phytochemical Analysis

DOI

2019

Ammonium fluoride-induced stabilization for anion attachment mass spectrometry: Facilitating the pseudotargeted profiling of bile acids submetabolome

Xian Su Cheng, Jian‐Liang Zhou, Zi‐Qi Shi, Yinghao Yin, Jianqun Liu, Han-Xiang Chen, Ping Li, Lifang Liu, Gui-Zhong Xin

Analytica Chimica Acta

DOI

2019

Chemical markers’ knockout coupled with UHPLC-HRMS-based metabolomics reveals anti-cancer integration effects of the curcuminoids of turmeric (Curcuma longa L.) on lung cancer cell line

Jian‐Liang Zhou, Jia‐Yi Zheng, Xia-Qian Cheng, Gui-Zhong Xin, Shuling Wang, Tian Xie

Journal of Pharmaceutical and Biomedical Analysis

DOI

2019

A readily 16O-/18O-isotopically-paired chiral derivatization approach for the quantification of 2-HG metabolic panel by liquid chromatography-Tandem mass spectrometry

Jia‐Yi Zheng, Xue Song Jiang, Jian‐Liang Zhou, Zi‐Qi Shi, Lifang Liu, Gui-Zhong Xin

Analytica Chimica Acta

DOI

2019

Development and validation of a systematic platform for broad-scale profiling of microbial metabolites

Xin-Nan Wang, Yinghao Yin, Xian Su Cheng, Lin Chen, Menglu Chen, Jia‐Yi Zheng, Yingying Jin, Jianqun Liu, Lifang Liu, Gui-Zhong Xin

Talanta

DOI

2019

Integrating chemical similarity and bioequivalence: A pilot study on quality consistency evaluation of dispensing granule and traditional decoction of Scutellariae Radix by a totality-of-the-evidence approach

Dan Liang, Yinghao Yin, Lan-Yun Miao, Xian Zheng, Wen Yuan Gao, Xiangdong Chen, Mei Wei, Shengjun Chen, Song Li, Gui-Zhong Xin, Ping Li, Hui‐Jun Li

Journal of Pharmaceutical and Biomedical Analysis

DOI

2018

天然药物分析实验课程双语教学模式的实践

杨杰，辛贵忠，许翔鸿，刘丽芳

《教育教学论坛》

2018

威灵仙中的三萜皂苷类成分及其抗关节炎作用机制的研究进展

郑佳逸，辛贵忠，刘丽芳

《中国野生植物资源》

2018

A chemical derivatization based UHPLC-LTQ-Orbitrap mass spectrometry method for accurate quantification of short-chain fatty acids in bronchoalveolar lavage fluid of asthma mice

Yingying Jin, Zi‐Qi Shi, Wen-Qi Chang, Lin‐Xiu Guo, Jian‐Liang Zhou, Jianqun Liu, Lifang Liu, Gui-Zhong Xin

Journal of Pharmaceutical and Biomedical Analysis

DOI

2017

Explore the effects of Huang-Lian-Jie-Du-Tang on Alzheimer’s disease by UPLC-QTOF/MS-based plasma metabolomics study

Li-Min Sun, Baojie Zhu, Hui-Ting Cao, Xinyi Zhang, Qichun Zhang, Gui-Zhong Xin, Linmei Pan, Lifang Liu, Hua-Xu Zhu

Journal of Pharmaceutical and Biomedical Analysis

DOI

2017

Development and validation of a LC/MS-based method for the measurement of intracellular superoxide anion

Zeyuan Wang, Yi Li, Wen-Qi Chang, Jia‐Yi Zheng, Ping Li, Lifang Liu, Gui-Zhong Xin

Analytica Chimica Acta

DOI

2017

Comparison of three officinal species of Callicarpa based on a biochemome profiling strategy with UHPLC-IT-MS and chemometrics analysis

Menglu Chen, Wen-Qi Chang, Jian‐Liang Zhou, Yinghao Yin, Wenrui Xia, Jianqun Liu, Lifang Liu, Gui-Zhong Xin

Journal of Pharmaceutical and Biomedical Analysis

DOI

2017

Rapid identification of herbal compounds derived metabolites using zebrafish larvae as the biotransformation system

Chen Wang, Yinghao Yin, Yingjie Wei, Zi‐Qi Shi, Jianqun Liu, Lifang Liu, Gui-Zhong Xin

Journal of Chromatography A

DOI

2017

A strategy to identify and quantify closely related adulterant herbal materials by mass spectrometry-based partial least squares regression

Li Wang, Lifang Liu, Jianying Wang, Zi‐Qi Shi, Wen-Qi Chang, Menglu Chen, Yinghao Yin, Yan Jiang, Hui‐Jun Li, Ping Li, Zhong‐Ping Yao, Gui-Zhong Xin

Analytica Chimica Acta

DOI

2016

基于色谱质谱联用的尿液代谢组学归一化方法

王丹丹，李萍，刘丽芳，辛贵忠

《中国新药杂志》

2016

Dose-response characteristics of Clematis triterpenoid saponins and clematichinenoside AR in rheumatoid arthritis rats by liquid chromatography/mass spectrometry-based serum and urine metabolomics

Rui Li, Lin‐Xiu Guo, Yi Li, Wen-Qi Chang, Jianqun Liu, Lifang Liu, Gui-Zhong Xin

Journal of Pharmaceutical and Biomedical Analysis

DOI

2016

Succinate/NLRP3 Inflammasome Induces Synovial Fibroblast Activation: Therapeutical Effects of Clematichinenoside AR on Arthritis

Yi Li, Jia‐Yi Zheng, Jianqun Liu, Jie Yang, Yang Liu, Chen Wang, Xiaonan Ma, Baolin Liu, Gui-Zhong Xin, Lifang Liu

Frontiers in Immunology

DOI

2016

An in vitro approach for lipolysis measurement using high-resolution mass spectrometry and partial least squares based analysis

Wen-Qi Chang, Jian‐Liang Zhou, Yi Li, Zi‐Qi Shi, Li Wang, Jie Yang, Ping Li, Lifang Liu, Gui-Zhong Xin

Analytica Chimica Acta

DOI

2016

Rapid authentication of Gastrodiae rhizoma by direct ionization mass spectrometry

H.Y. Wong, Bin Hu, Pui‐Kin So, Chi-On Chan, Daniel Kam‐Wah Mok, Gui-Zhong Xin, Ping Li, Zhong‐Ping Yao

Analytica Chimica Acta

DOI

2016

Specific targeted quantification combined with non-targeted metabolite profiling for quality evaluation of Gastrodia elata tubers from different geographical origins and cultivars

Xiaodong Ma, Ya-Xi Fan, Cancan Jin, Fei Wang, Gui-Zhong Xin, Ping Li, Hui‐Jun Li

Journal of Chromatography A

DOI

2016

Inhibition of Mitochondrial Fission and NOX2 Expression Prevent NLRP3 Inflammasome Activation in the Endothelium: The Role of Corosolic Acid Action in the Amelioration of Endothelial Dysfunction

Yi Li, Zhihui Zhou, Meihong Chen, Jie Yang, Jing Leng, Guosheng Cao, Gui-Zhong Xin, Lifang Liu, Junping Kou, Baolin Liu, Ping Li, Xiaodong Wen

Antioxidants and Redox Signaling

DOI

2015

UPLC-Triple TOF-MS方法鉴定野漆树苷在大鼠体内的代谢物

刘敬，王清，辛贵忠，刘丽芳，刘建群

《中国野生植物资源》

2015

基于LC/QTOF-MS/MS法鉴定兰考泡桐花化学成分

王清，刘敬，陈晓兰，张建，刘丽芳，辛贵忠

《中医药学报》

2015

Structural characterization and discrimination of Chinese medicinal materials with multiple botanical origins based on metabolite profiling and chemometrics analysis: Clematidis Radix et Rhizoma as a case study

Lin‐Xiu Guo, Rui Li, Ke Liu, Jie Yang, Hui‐Jun Li, Song‐Lin Li, Jianqun Liu, Lifang Liu, Gui-Zhong Xin

Journal of Chromatography A

DOI

2015

Global detection and semi‐quantification of Fritillaria alkaloids in Fritillariae Ussuriensis Bulbus by a non‐targeted multiple reaction monitoring approach

Li Wang, Zhong‐Ping Yao, Ping Li, Sibao Chen, Pui‐Kin So, Zi‐Qi Shi, Bin Hu, Lifang Liu, Gui-Zhong Xin

Journal of Separation Science

DOI

2015

A direct ionization mass spectrometry-based approach for differentiation of medicinal Ephedra species

Gui-Zhong Xin, Bin Hu, Zi‐Qi Shi, Jia‐Yi Zheng, Li Wang, Wen-Qi Chang, Ping Li, Zhong‐Ping Yao, Lifang Liu

Journal of Pharmaceutical and Biomedical Analysis

DOI

2015

Thin layer chromatography coupled with electrospray ionization mass spectrometry for direct analysis of raw samples

Bin Hu, Gui-Zhong Xin, Pui‐Kin So, Zhong‐Ping Yao

Journal of Chromatography A

DOI

2014

Camptothecin and its Analogs Reduce Amyloid-β Production and Amyloid-β42-Induced IL-1β Production

Ju Wang, Zi‐Qi Shi, Mu Zhang, Gui-Zhong Xin, Tao Pang, Ping Hong Zhou, Jun Chen, Lian‐Wen Qi, Hua Qiang Yang, Xiaojun Xu, Ping Li

Journal of Alzheimer s Disease

DOI

2014

Identification of effective combinatorial markers for quality standardization of herbal medicines

Zi‐Qi Shi, De-Fang Song, Ruo-Qian Li, Hua Qiang Yang, Lian‐Wen Qi, Gui-Zhong Xin, Ding-Qian Wang, Hui‐Peng Song, Jun Chen, Haiping Hao, Ping Li

Journal of Chromatography A

DOI

2013

石蒜科生物碱的药理作用研究进展

宋德芳，石子琪，辛贵忠，李若倩，陈君，李萍

《中国新药杂志》

2012

微透析及其联用技术在中药研究中的应用

曹柳，辛贵忠，闻晓东，李萍

《中国新药杂志》

2012

Triptolide Inhibits Amyloid-β Production and Protects Neural Cells by Inhibiting CXCR2 Activity

Ju Wang, Zi‐Qi Shi, Xiaojun Xu, Gui-Zhong Xin, Jun Chen, Lian‐Wen Qi, Ping Li

Journal of Alzheimer s Disease

DOI

2012

Direct pharmacokinetic analysis of puqietinone by in vivo microdialysis sampling and turbulent-flow chromatography coupled with liquid chromatography–mass spectrometry

Gui-Zhong Xin, Liu Cao, Zi‐Qi Shi, Hui‐Jun Li, Xiaodong Wen, Jun Chen, Lian‐Wen Qi, Ping Li

Journal of Chromatography B

DOI

2011

基于质谱检测的相关色谱技术在阿尔茨海默病诊断中的应用

王鼎乾，辛贵忠，石子琪，陈君，李萍

《色谱》

2011

In vivo microdialysis with LC–MS for analysis of spinosin and its interaction with cyclosporin A in rat brain, blood and bile

Ronghua Ma, Jie Yang, Lian‐Wen Qi, Gui-Zhong Xin, Chong‐Zhi Wang, Chun‐Su Yuan, Xiaodong Wen, Ping Li

Journal of Pharmaceutical and Biomedical Analysis

DOI

2011

Strategies for Integral Metabolism Profile of Multiple Compounds in Herbal Medicines: Pharmacokinetics, Metabolites Characterization and Metabolic Interactions

Gui-Zhong Xin, Lian‐Wen Qi, Zi‐Qi Shi, Ping Li, Haiping Hao, Guangji Wang, Jing Shang

Current Drug Metabolism

DOI

2011

Fishing and Knockout (FAK) Strategy for Quality Control of Traditional Chinese Medicines (TCMs)

P Li, Qi Li, Gui-Zhong Xin

Planta Medica

DOI

2010

HPLC-ELSD测定太白贝母和瓦布贝母中贝母辛的含量

刘晶，王曙，辛贵忠，李会军，李萍

《中国药学杂志》

2010

Characterization and identification of steroidal alkaloids in Fritillaria species using liquid chromatography coupled with electrospray ionization quadrupole time-of-flight tandem mass spectrometry

Jian‐Liang Zhou, Gui-Zhong Xin, Zi‐Qi Shi, Mei‐Ting Ren, Lian‐Wen Qi, Hui‐Jun Li, Ping Li

Journal of Chromatography A

DOI

2010

Turbulent-flow chromatography coupled on-line to fast high-performance liquid chromatography and mass spectrometry for simultaneous determination of verticine, verticinone and isoverticine in rat plasma

Gui-Zhong Xin, Jian‐Liang Zhou, Lian‐Wen Qi, Changyin Li, Peng Liu, Hui‐Jun Li, Xiaodong Wen, Ping Li

Journal of Chromatography B

DOI

2009

忍冬藤质量标准研究

辛贵忠，钱正明，周建良，李会军，李萍

《中国药学杂志》

2008

Simultaneous Determination of Nine Bioactive Constituents of Caulis Lonicerae Japonicae by High-Performance Liquid Chromatography Coupled with Mass Spectrometry

Hui‐Jun Li, Zhengming Qian, Ping Li, Mei‐Ting Ren, Jun Chen, Gui-Zhong Xin

Natural Product Communications

DOI

会议论文

2018

Lasso-based Prediction of Collision Cross Section Values for Lipids

Jianying Wang, Yinghao Yin, Guizhong Xin, Zhongping Yao

《2018年中国质谱学术大会（CMSC 2018）论文集》

DOI

预印本

2026

Eucommia ulmoides leaf alleviates osteoarthritis by modulating the gut FXR-joint GLP-1R axis: A function-guided multi-omics integrated study

Kai-Xuan Xu, Shi Sun, Hong-Xu Leng, Kai-Fan Zheng, Gui-Zhong Xin, Ziqi Shi

SSRN Electronic Journal

DOI

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