高千千｜重庆医科大学｜学者主页

2026

An SPP1-SOCS1 pathway constrains interferon responses in tumor-associated macrophages and shapes an immunosuppressive tumor microenvironment

Liangzhan sun, Xiaojing Chu, Tingting Kong, Xirui Chen, Jianing Ru, Qianqian Gao, Wei Zhou, Xiliang Wang, Sijin Cheng, L L Zhu, Zemin Zhang

Immunity

DOI

2022

Knockdown of TMEM132A restrains the malignant phenotype of gastric cancer cells via inhibiting Wnt signaling

Qianqian Gao, Yu-Fang Chen, Ling-Ping Yue, Ziyan Li, Meihua Wang

Nucleosides, Nucleotides & Nucleic Acids

DOI

2022

High-efficiency of genetic modification using CRISPR/Cpf1 system for engineered CAR-T cell therapy.

Renpeng Ding, Cheng-chi Chao, Qianqian Gao

Methods in Cell Biology

DOI

2021

Single-cell transcriptome analysis of the heterogeneous effects of differential expression of tumor PD-L1 on responding TCR-T cells

Renpeng Ding, Shang Liu, Shanshan Wang, Huanyi Chen, Fei Wang, Qumiao Xu, Linnan Zhu, Xuan Dong, Ying Gu, Xiu-Qing Zhang, Cheng-chi Chao, Qianqian Gao

Theranostics

DOI

2021

Quadruple‐editing of the MAPK and PI3K pathways effectively blocks the progression of KRAS‐mutated colorectal cancer cells

Zaozao Wang, B. Kang, Qianqian Gao, Lei Huang, Yingcong Fan, Jianhong Yu, Jiabo Di, B. Jiang, Feng Gao, Dan Wang, Haixi Sun, Ying Gu, Jian Li, Xiang-Qian Su

Cancer Science

DOI

2021

Case Report: Transformation From Cold to Hot Tumor in a Case of NSCLC Neoadjuvant Immunochemotherapy Pseudoprogression

W. Jia, Hui Zhu, Qianqian Gao, Jian Sun, F. Tan, Qun Liu, Hong-Bo Guo, Jin-Ming Yu

Frontiers in Immunology

DOI

2021

CAR-T Cell Therapy: Challenges and Optimization.

Mei Luo, Hong-Chang Zhang, Linnan Zhu, Qumiao Xu, Qianqian Gao

Critical Reviews in Immunology

DOI

2021

The Targeting Effect of Cetuximab Combined with PD-L1 Blockade against EGFR-Expressing Tumors in a Tailored CD16-CAR T-Cell Reporter System

Yi-Jian Li, Qianqian Gao, Huan Liu, Shufen Lin, Huanyi Chen, Renpeng Ding, Ying Gu, Cheng-chi Chao, Xuan Dong

Cancer Investigation

DOI

2021

Gene Knock-in Strategy for Engineered T-cell Therapy

Qianqian Gao, Renpeng Ding, Cheng-chi Chao

DOI

2020

Abstract 2204: Enhancing anti-tumor efficacy of MART-1-specific TCR-T cells by CRISPR-Cas9-based PD-1 disruption

Qianqian Gao, Renpeng Ding, Huanyi Chen, Qumiao Xu, Linnan Zhu, Xuan Dong, Ying Gu, Cheng-chi Chao

Immunology

DOI

2020

Single-cell Approach to Generate Functional TCR-Ts: A Potential Accelerator of TCR-T Cell Therapy for Infectious Diseases

Qumiao Xu, Ziyi Li, Fei Wang, Zhen-Kun Zhuang, Yanling Liang, Qianqian Gao, Xuan Dong, Linnan Zhu

Journal of cellular immunology

DOI

2020

Regulation of specific cell clusters in TCR-T cells responding to differential expression of tumor PD-L1

Renpeng Ding, Shang Liu, Huanyi Chen, B. Kang, R. Drmanac, Ying Gu, Xuan Dong, Qianqian Gao

bioRxiv

DOI

2020

Neuropilin-1, A Rising Star in Cancer Immunotherapy

Qianqian Gao, Qumiao Xu

DOI

2020

A single-cell approach to engineer CD8+ T cells targeting cytomegalovirus

Fei Wang, Qumiao Xu, Zhen-Kun Zhuang, Ziyi Li, Qianqian Gao, Ya-Ling Huang, Yong-Lun Luo, Xiu-Qing Zhang, Linnan Zhu, Cheng-chi Chao

Cellular & Molecular Immunology

DOI

2020

Exosomal lncRNA UCA1 from cancer‐associated fibroblasts enhances chemoresistance in vulvar squamous cell carcinoma cells

Qianqian Gao, Xiaohui Fang, Yu-Fang Chen, Ziyan Li, Meihua Wang

The journal of obstetrics and gynaecology research

DOI

2020

Single-Cell Sequencing of Peripheral Mononuclear Cells Reveals Distinct Immune Response Landscapes of COVID-19 and Influenza Patients

Linnan Zhu, Peng-Hui Yang, Yingze Zhao, Zhen-Kun Zhuang, Zhifeng Wang, Rui Song, Jie Zhang, Chuan-Yu Liu, Qianqian Gao, Qumiao Xu, Xiaoyu Wei, Haixi Sun, Beiwei Ye, Ya-Nan Wu, Ning Zhang, Guanglin Lei, Ling-Xiang Yu, Jin Yan, G. Diao, Fan-Ping Meng, Chang-Qing Bai, P. Mao, Ye-Ya Yu, Mingyue Wang, Yue Yuan, Q. Deng, Ziyi Li, Yunting Huang, G. Hu, Yang Liu, Xiao-Qian Wang, Ziqian Xu, Peipei Liu, Y. Bi, Yi Shi, Shao-Geng Zhang, Zhi-Hai Chen, Jian Wang, Xun Xu, Gui-Zhen Wu, Fu-Sheng Wang, G. Gao, Long-Qi Liu, William J. Liu

Immunity

DOI

2020

The Pathogenesis and Prevention of Port-Site Metastasis in Gynecologic Oncology

Qianqian Gao, Ling Guo, Bo Wang

Cancer Management and Research

DOI

2020

Overlap time is an independent risk factor of radiation pneumonitis for patients treated with simultaneous EGFR-TKI and thoracic radiotherapy

W. Jia, Qianqian Gao, Min Wang, Ji Li, W. Jing, Jin-Ming Yu, Hui Zhu

Radiation Oncology

DOI

2020

The expression of PDCD1 and CD274 in T cells and macrophages correlated positively with COVID-19 severity

Qianqian Gao, Shang Liu, Renpeng Ding, Huanyi Chen, Xuan Dong, Jiarui Xie, Yi-Jian Li, Lei Chen, Huan Liu, Feng Mu

bioRxiv

DOI

2020

Selective targeting of the oncogenic KRAS G12S mutant allele by CRISPR/Cas9 induces efficient tumor regression

Qianqian Gao, Wen-Jie Ouyang, B. Kang, Xu Han, Ying Xiong, Renpeng Ding, Yi-Jian Li, Fei Wang, Lei Huang, Lei Chen, Dan Wang, Xuan Dong, Zhao Zhang, Yan-Shan Li, Baichen Ze, Yong Hou, Huan-Ming Yang, Yuan-Yuan Ma, Ying Gu, Cheng-chi Chao

Theranostics

DOI

2019

The potential mechanism, recognition and clinical significance of tumor pseudoprogression after immunotherapy

W. Jia, Qianqian Gao, A. Han, Hui Zhu, Jin-Ming Yu

Cancer Biology and Medicine

DOI

2019

PAK4, a target of miR-9-5p, promotes cell proliferation and inhibits apoptosis in colorectal cancer

Meihua Wang, Qianqian Gao, Yu-Fang Chen, Ziyan Li, Ling-Ping Yue, Yun-Jian Cao

Cellular & Molecular Biology Letters

DOI

2019

Long noncoding RNA THAP9-AS1 is induced by Helicobacter pylori and promotes cell growth and migration of gastric cancer

W. Jia, Jiaqi Zhang, Fang Ma, Shengjie Hao, Xia Li, Rui-Ting Guo, Qianqian Gao, Yundong Sun, J. Jia, Wenjuan Li

OncoTargets and Therapy

DOI

2019

Therapeutic potential of CRISPR/Cas9 gene editing in engineered T‐cell therapy

Qianqian Gao, Xuan Dong, Qumiao Xu, Linnan Zhu, Fei Wang, Yong Hou, Cheng-chi Chao

Cancer Medicine

DOI

2018

Peritumoral implantation of hydrogel-containing nanoparticles and losartan for enhanced nanoparticle penetration and antitumor effect

Hai-Jun Shen, Qianqian Gao, Qiumian Ye, Shi Yang, Yuqianxun Wu, Qin Huang, Xiaona Wang, Zhenhua Sun

International Journal of Nanomedicine

DOI

2015

Significant association between IL-32 gene polymorphisms and susceptibility to endometrial cancer in Chinese Han women

Xiu-Zhang Yu, Bin Zhou, Zhu Zhang, Qianqian Gao, Yan-Yun Wang, Yaping Song, Yan Pu, Yue Chen, Ruiqi Duan, Lin Zhang, M. Xi

Tumor Biology

DOI

2014

Association of an insertion/deletion polymorphism in IL1A 3'-UTR with risk for cervical carcinoma in Chinese Han Women.

Yan Pu, Zhu Zhang, Bin Zhou, Peng Chen, Kui Zhang, Yaping Song, Qianqian Gao, Ka-Na Wang, Yi Quan, M. Xi, Lin Zhang

Human Immunology

DOI

2014

A polymorphism at miRNA-122-binding site in the IL-1α 3′UTR is associated with risk of epithelial ovarian cancer

Zhu Zhang, Bin Zhou, Qianqian Gao, Yuke Wu, Kui Zhang, Yan Pu, Yaping Song, Lin Zhang, M. Xi

Familial Cancer

DOI

2013

Prognostic value of IL-27 polymorphisms and the susceptibility to epithelial ovarian cancer in a Chinese population

Zhu Zhang, Bin Zhou, Yuke Wu, Qianqian Gao, Kui Zhang, Yaping Song, Lin Zhang, M. Xi

Immunogenetics

DOI

2012

Association between IL17 Polymorphisms and Risk of Cervical Cancer in Chinese Women

Yi Quan, Bin Zhou, Yan-Yun Wang, Ruiqi Duan, Ka-Na Wang, Qianqian Gao, Shao-Qing Shi, Yaping Song, Lin Zhang, M. Xi

Clinical and Developmental Immunology

DOI

高千千

精选作品

期刊论文

An SPP1-SOCS1 pathway constrains interferon responses in tumor-associated macrophages and shapes an immunosuppressive tumor microenvironment

Knockdown of TMEM132A restrains the malignant phenotype of gastric cancer cells via inhibiting Wnt signaling

High-efficiency of genetic modification using CRISPR/Cpf1 system for engineered CAR-T cell therapy.

Single-cell transcriptome analysis of the heterogeneous effects of differential expression of tumor PD-L1 on responding TCR-T cells

Quadruple‐editing of the MAPK and PI3K pathways effectively blocks the progression of KRAS‐mutated colorectal cancer cells

Case Report: Transformation From Cold to Hot Tumor in a Case of NSCLC Neoadjuvant Immunochemotherapy Pseudoprogression

CAR-T Cell Therapy: Challenges and Optimization.

The Targeting Effect of Cetuximab Combined with PD-L1 Blockade against EGFR-Expressing Tumors in a Tailored CD16-CAR T-Cell Reporter System

Gene Knock-in Strategy for Engineered T-cell Therapy

Abstract 2204: Enhancing anti-tumor efficacy of MART-1-specific TCR-T cells by CRISPR-Cas9-based PD-1 disruption

Single-cell Approach to Generate Functional TCR-Ts: A Potential Accelerator of TCR-T Cell Therapy for Infectious Diseases

Regulation of specific cell clusters in TCR-T cells responding to differential expression of tumor PD-L1

Neuropilin-1, A Rising Star in Cancer Immunotherapy

A single-cell approach to engineer CD8+ T cells targeting cytomegalovirus

Exosomal lncRNA UCA1 from cancer‐associated fibroblasts enhances chemoresistance in vulvar squamous cell carcinoma cells

Single-Cell Sequencing of Peripheral Mononuclear Cells Reveals Distinct Immune Response Landscapes of COVID-19 and Influenza Patients

The Pathogenesis and Prevention of Port-Site Metastasis in Gynecologic Oncology

Overlap time is an independent risk factor of radiation pneumonitis for patients treated with simultaneous EGFR-TKI and thoracic radiotherapy

The expression of PDCD1 and CD274 in T cells and macrophages correlated positively with COVID-19 severity

Selective targeting of the oncogenic KRAS G12S mutant allele by CRISPR/Cas9 induces efficient tumor regression

The potential mechanism, recognition and clinical significance of tumor pseudoprogression after immunotherapy

PAK4, a target of miR-9-5p, promotes cell proliferation and inhibits apoptosis in colorectal cancer

Long noncoding RNA THAP9-AS1 is induced by Helicobacter pylori and promotes cell growth and migration of gastric cancer

Therapeutic potential of CRISPR/Cas9 gene editing in engineered T‐cell therapy

Peritumoral implantation of hydrogel-containing nanoparticles and losartan for enhanced nanoparticle penetration and antitumor effect

Significant association between IL-32 gene polymorphisms and susceptibility to endometrial cancer in Chinese Han women

Association of an insertion/deletion polymorphism in IL1A 3'-UTR with risk for cervical carcinoma in Chinese Han Women.

A polymorphism at miRNA-122-binding site in the IL-1α 3′UTR is associated with risk of epithelial ovarian cancer

Prognostic value of IL-27 polymorphisms and the susceptibility to epithelial ovarian cancer in a Chinese population

Association between IL17 Polymorphisms and Risk of Cervical Cancer in Chinese Women

研究方向